@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XZ66: (2018-01-12 )
MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQNVEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDFGRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAVLSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDGIVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWNEDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNHKIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA
Atome Classification :
(20 SA)
.........10........20........30........40........50.....-...60.........70........80........90........100.......110..-.....120.......130.......140......----.150...----.----...160....-...170.......180.....-..190.......200.......210.......220.......230.......240.......250.......260.......270.......280.....-..290...-...-.-300.......310.......320.......330......-.340.......----350....----...360.......370..----------.....---------380.......390--------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
S
K
E
M
L
N
A
L
D
A
L
E
A
EKGI
S
K
E
I
V
I
D
A
L
E
A
A
L
V
S
A
Y
K
R
HYGQAQ
N
V
E
V
E
F
DQKKG
K
I
-
H
V
Y
A
-
V
K
E
V
T
E
E
V
M
D
S
Q
L
E
V
S
LK
D
A
L
L
INPAYEIG
D
T
I
R
F
E
V
T
P
K
D
F
G
R
I
A
A
Q
T
A
K
Q
V
I
-
L
Q
R
V
R
E
A
E
R
T
I
I
Y
N
E
F
S
A
Y
E
K
D
I
M
Q
G
I
V
E
RQDK
R
----
Y
I
Y
V
NL
G
----
K
----
I
E
A
V
L
S
K
Q
DQ-M
P
N
E
FYQP
H
D
R
I
K
V
Y
V
S
R
VEN-TSKG
P
Q
V
F
V
SRS
H
P
D
L
L
R
R
L
F
E
Q
E
V
P
E
V
Y
D
G
I
V
E
I
V
S
I
A
R
EAGDR
S
K
V
A
VRSNDPNI
D
A
V
GTCVGPK
G
Q
R
V
Q
A
I
V
N
E
LKGEN
M
D
I
V
EWNED
P
A
V
F
I
ANAL-
N
P
A
Q
V
M
D
V
-
I
FD-E-TNP
K
A
C
T
V
V
VPD
Y
Q
L
S
L
A
IGKRGQN
A
R
L
A
A
K
LTN
H
K
I
D
I-KSE
S
D
M
T
E
F
Y
E
----
N
Q
E
Q
Q
K
E
----
T
E
E
L
H
D
E
A
I
VQSDLTDDE----------Y
E
T
I
A---------FNNE
T
V
EEKPEA---------------------------
27
HHSearch
84.36
40%
-97
- C7 -
-
4MTN
-
?
A:
[5-375]
-
G
N
E
V
L
R
I
V
D
S
I
H
R
D
K
S
I
D
K
E
I
V
F
E
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V
E
Q
A
I
L
S
A
A
R
K
H
F
G
E
E
E
V
I
E
V
H
I
D
R
T
S
G
Q
P
-
M
V
K
T
-
N
G
----------
R
E
I
D
--------
R
-
D
E
L
G
D
---------
I
L
G
R
I
S
A
Q
T
-
K
Q
V
M
-
I
Q
K
I
R
E
A
E
R
D
T
L
F
D
E
Y
A
Q
L
R
G
Q
I
V
S
G
T
V
T
R
N
E
G
S
----
A
I
T
V
N
I
G
----
K
----
A
E
A
I
L
P
R
S
E
M
-
I
P
G
E
S
H
R
P
N
E
R
I
R
A
V
V
L
E
V
K
K
-
M
G
P
R
V
R
V
V
L
S
R
A
H
P
D
F
V
R
R
L
L
E
L
E
I
P
E
V
N
E
R
I
I
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I
R
S
L
A
R
E
A
G
Y
R
T
K
V
A
V
S
C
A
D
S
N
I
D
P
V
G
A
C
V
G
V
R
G
A
R
I
R
N
V
G
E
E
L
G
G
E
R
I
E
V
V
R
W
N
D
S
L
Q
V
L
V
P
N
A
M
-
Q
P
S
E
V
E
D
V
-
I
L
C
-
P
-
M
-
L
G
R
V
L
V
L
V
R
D
D
Q
L
S
L
A
I
G
K
R
G
Q
N
V
R
L
A
S
K
L
V
G
W
D
I
D
V
-
M
T
R
E
E
L
D
Q
Q
L
D
Q
A
V
V
A
Y
S
Q
I
P
G
----
V
S
E
E
L
A
E
G
L
V
S
Q
G
F
L
S
F
E
D
L
S
V
IE
P
D
E
L
M
E
M
G
S
---------
L
T
Q
E
Q
A
D
V
-------------------------------
2
PsiBlast_PDB
81.38
50%
-76
- C7 -
-
1L2F
-
?
A:
[5-339]
----
L
L
E
A
L
D
Q
L
E
E
E
K
G
I
S
K
E
E
V
I
P
I
L
E
K
A
L
V
S
A
Y
R
K
N
F
G
N
S
K
N
V
E
V
V
I
D
R
N
T
G
N
I
-
K
V
Y
Q
-
L
L
E
V
V
E
E
V
E
D
P
A
T
Q
I
S
L
E
E
A
K
K
I
D
P
L
A
E
V
G
S
I
V
K
K
E
L
N
V
K
N
F
G
R
I
A
A
Q
T
A
K
Q
V
L
-
I
Q
R
I
R
E
L
E
K
E
K
Q
F
E
K
Y
S
E
L
K
G
T
V
T
T
A
E
V
I
R
V
M
G
E
----
W
A
D
I
R
I
G
----
K
----
L
E
T
R
L
P
K
K
E
W
-
I
P
G
E
E
I
K
A
G
D
L
V
K
V
Y
I
I
D
V
V
K
-
T
T
K
G
P
K
I
L
V
S
R
R
V
P
E
F
V
I
G
L
M
K
L
E
I
P
E
V
E
N
G
I
V
E
I
K
A
I
A
R
E
P
G
V
R
T
K
V
A
V
A
S
N
D
P
N
V
D
P
I
G
A
C
I
G
E
G
G
S
R
I
A
A
I
L
K
E
L
K
G
E
K
L
D
V
L
K
W
S
D
D
P
K
Q
L
I
A
N
A
L
-
A
P
A
T
V
I
E
V
E
I
L
D
-
K
-
E
N
-
K
A
A
R
V
L
V
P
P
T
Q
L
S
L
A
I
G
K
G
G
Q
N
A
R
L
A
A
K
L
T
G
W
K
I
D
I
-
K
----------------------------------------------------------------------------------------------------------
17
Fugue
81.02
49%
-77
- C7 -
-
1HH2
-
?
P:
[1-344]
M
N
I
G
L
L
E
A
L
D
Q
L
E
E
E
K
G
I
S
K
E
E
V
I
P
I
L
E
K
A
L
V
S
A
Y
R
K
N
F
G
N
S
K
N
V
E
V
V
I
D
R
N
T
G
N
I
-
K
V
Y
Q
-
L
L
E
V
V
E
E
V
E
D
P
A
T
Q
I
S
L
E
E
A
K
K
I
D
P
L
A
E
V
G
S
I
V
K
K
E
L
N
V
K
N
F
G
R
I
A
A
Q
T
A
K
Q
V
L
-
I
Q
R
I
R
E
L
E
K
E
K
Q
F
E
K
Y
S
E
L
K
G
T
V
T
T
A
E
V
I
R
V
M
G
E
----
W
A
D
I
R
I
G
----
K
----
L
E
T
R
L
P
K
K
E
W
-
I
P
G
E
E
I
K
A
G
D
L
V
K
V
Y
I
I
D
V
V
K
-
T
T
K
G
P
K
I
L
V
S
R
R
V
P
E
F
V
I
G
L
M
K
L
E
I
P
E
V
E
N
G
I
V
E
I
K
A
I
A
R
E
P
G
V
R
T
K
V
A
V
A
S
N
D
P
N
V
D
P
I
G
A
C
I
G
E
G
G
S
R
I
A
A
I
L
K
E
L
K
G
E
K
L
D
V
L
K
W
S
D
D
P
K
Q
L
I
A
N
A
L
-
A
P
A
T
V
I
E
V
-
E
I
L
-
D
-
K
E
N
K
A
A
R
V
L
V
P
P
T
Q
L
S
L
A
I
G
K
G
G
Q
N
A
R
L
A
A
K
L
T
G
W
K
I
D
I
-
K
P
I
M
N
L
-----------------------------------------------------------------------------------------------------
28
HHSearch
78.41
50%
-50
- C7 -
-
1HH2
-
?
P:
[1-341]
M
N
I
G
L
L
E
A
L
D
Q
L
E
E
E
K
G
I
S
K
E
E
V
I
P
I
L
E
K
A
L
V
S
A
Y
R
K
N
F
G
N
S
K
N
V
E
V
V
I
D
R
N
T
G
N
I
-
K
V
Y
Q
-
L
L
E
V
V
E
E
V
E
D
P
A
T
Q
I
S
L
E
E
A
K
K
I
D
P
L
A
E
V
G
S
I
V
K
K
E
L
N
V
K
N
F
G
R
I
A
A
Q
T
A
K
Q
V
L
-
I
Q
R
I
R
E
L
E
K
E
K
Q
F
E
K
Y
S
E
L
K
G
T
V
T
T
A
E
V
I
R
V
M
G
E
----
W
A
D
I
R
I
G
----
K
----
L
E
T
R
L
P
K
K
E
W
-
I
P
G
E
E
I
K
A
G
D
L
V
K
V
Y
I
I
D
V
V
K
-
T
T
K
G
P
K
I
L
V
S
R
R
V
P
E
F
V
I
G
L
M
K
L
E
I
P
E
V
E
N
G
I
V
E
I
K
A
I
A
R
E
P
G
V
R
T
K
V
A
V
A
S
N
D
P
N
V
D
P
I
G
A
C
I
G
E
G
G
S
R
I
A
A
I
L
K
E
L
K
G
E
K
L
D
V
L
K
W
S
D
D
P
K
Q
L
I
A
N
A
L
-
A
P
A
T
V
I
E
V
-
E
I
L
D
K
-
E
-
N
K
A
A
R
V
L
V
P
P
T
Q
L
S
L
A
I
G
K
G
G
Q
N
A
R
L
A
A
K
L
T
G
W
K
I
D
I
-
K
P
I
--------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
76.57
50%
-50
- C7 -
-
1HH2
-
?
P:
[1-339]
M
N
I
G
L
L
E
A
L
D
Q
L
E
E
E
K
G
I
S
K
E
E
V
I
P
I
L
E
K
A
L
V
S
A
Y
R
K
N
F
G
N
S
K
N
V
E
V
V
I
D
R
N
T
G
N
I
-
K
V
Y
Q
-
L
L
E
V
V
E
E
V
E
D
P
A
T
Q
I
S
L
E
E
A
K
K
I
D
P
L
A
E
V
G
S
I
V
K
K
E
L
N
V
K
N
F
G
R
I
A
A
Q
T
A
K
Q
V
L
-
I
Q
R
I
R
E
L
E
K
E
K
Q
F
E
K
Y
S
E
L
K
G
T
V
T
T
A
E
V
I
R
V
M
G
E
----
W
A
D
I
R
I
G
----
K
----
L
E
T
R
L
P
K
K
E
W
-
I
P
G
E
E
I
K
A
G
D
L
V
K
V
Y
I
I
D
V
V
K
-
T
T
K
G
P
K
I
L
V
S
R
R
V
P
E
F
V
I
G
L
M
K
L
E
I
P
E
V
E
N
G
I
V
E
I
K
A
I
A
R
E
P
G
V
R
T
K
V
A
V
A
S
N
D
P
N
V
D
P
I
G
A
C
I
G
E
G
G
S
R
I
A
A
I
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E
L
K
G
E
K
L
D
V
L
K
W
S
D
D
P
K
Q
L
I
A
N
A
L
-
A
P
A
T
V
I
E
V
E
I
L
D
-
K
-
E
N
-
K
A
A
R
V
L
V
P
P
T
Q
L
S
L
A
I
G
K
G
G
Q
N
A
R
L
A
A
K
L
T
G
W
K
I
D
I
-
K
----------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
72.34
39%
-14
- C7 -
-
4MTN
-
?
A:
[7-318]
---
E
V
L
R
I
V
D
S
I
H
R
D
K
S
I
D
K
E
I
V
F
E
G
V
E
Q
A
I
L
S
A
A
R
K
H
F
G
E
E
E
V
I
E
V
H
I
D
R
T
S
G
Q
P
-
M
V
K
T
N
G
R
E
I
D
R
D
--------------------
E
L
G
D
I
---------
L
G
R
I
S
A
Q
T
-
K
Q
V
M
-
I
Q
K
I
R
E
A
E
R
D
T
L
F
D
E
Y
A
Q
L
R
G
Q
I
V
S
G
T
V
T
R
N
E
G
S
----
A
I
T
V
N
I
G
----
K
----
A
E
A
I
L
P
R
S
E
M
-
I
P
G
E
S
H
R
P
N
E
R
I
R
A
V
V
L
E
V
K
K
-
M
G
P
R
V
R
V
V
L
S
R
A
H
P
D
F
V
R
R
L
L
E
L
E
I
P
E
V
N
E
R
I
I
E
I
R
S
L
A
R
E
A
G
Y
R
T
K
V
A
V
S
C
A
D
S
N
I
D
P
V
G
A
C
V
G
V
R
G
A
R
I
R
N
V
G
E
E
L
G
G
E
R
I
E
V
V
R
W
N
D
S
L
Q
V
L
V
P
N
A
M
-
Q
P
S
E
V
E
D
V
-
I
L
C
-
P
-
M
L
G
R
V
L
-
V
L
V
R
D
D
Q
L
S
L
A
I
G
K
R
G
Q
N
V
R
L
A
S
K
L
V
G
W
D
I
D
V
-
M
T
R
E
E
L
-----------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
71.01
38%
-17
- C7 -
-
5LM7
-
?
A:
[3-346]
M
N
K
E
I
L
A
V
V
E
A
V
S
N
E
K
A
L
P
R
E
K
I
F
E
A
L
E
S
A
L
A
T
A
T
K
K
K
Y
E
Q
E
I
D
V
R
V
Q
I
D
R
K
S
G
D
F
-
D
T
F
R
-
R
W
L
V
V
D
E
V
T
Q
P
T
K
E
I
T
L
E
A
A
R
Y
E
D
E
S
L
N
L
G
D
Y
V
E
D
Q
I
E
S
V
T
F
D
R
I
T
T
Q
T
A
K
Q
V
I
-
V
Q
K
V
R
E
A
E
R
A
M
V
V
D
Q
F
R
E
H
E
G
E
I
I
T
G
V
V
K
K
V
N
R
D
----
N
I
S
L
D
L
G
----
N
N---
A
E
A
V
I
L
R
E
D
M
-
L
P
R
E
N
F
R
P
G
D
R
V
R
G
V
L
Y
S
V
R
P
-
E
A
R
G
A
Q
L
F
V
T
R
S
K
P
E
M
L
I
E
L
F
R
I
E
V
P
E
I
G
E
E
V
I
E
I
K
A
A
A
R
D
P
G
S
R
A
K
I
A
V
K
T
N
D
K
R
I
D
P
V
G
A
C
V
G
M
R
G
A
R
V
Q
A
V
S
T
E
L
G
G
E
R
I
D
I
V
L
W
D
D
N
P
A
Q
F
V
I
N
A
M
-
A
P
A
D
V
A
S
I
-
V
V
D
-
E
--
D
K
H
T
M
D
I
A
V
E
A
G
N
L
A
Q
A
I
G
R
N
G
Q
N
V
R
L
A
S
Q
L
S
G
W
E
L
N
V
-
M
T
V
D
D
L
-----------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
70.50
38%
-19
- C7 -
-
5MS0
-
NUSA_ECOLI
M:
[3-346]
M
N
K
E
I
L
A
V
V
E
A
V
S
N
E
K
A
L
P
R
E
K
I
F
E
A
L
E
S
A
L
A
T
A
T
K
K
K
Y
E
Q
E
I
D
V
R
V
Q
I
D
R
K
S
G
D
F
-
D
T
F
R
-
R
W
L
V
V
D
E
V
T
Q
P
T
K
E
I
T
L
E
A
A
R
Y
E
D
E
S
L
N
L
G
D
Y
V
E
D
Q
I
E
S
V
T
F
D
R
I
T
T
Q
T
A
K
Q
V
I
-
V
Q
K
V
R
E
A
E
R
A
M
V
V
D
Q
F
R
E
H
E
G
E
I
I
T
G
V
V
K
K
V
N
R
D
----
N
I
S
L
D
L
G
----
N
N---
A
E
A
V
I
L
R
E
D
M
-
L
P
R
E
N
F
R
P
G
D
R
V
R
G
V
L
Y
S
V
R
P
-
E
A
R
G
A
Q
L
F
V
T
R
S
K
P
E
M
L
I
E
L
F
R
I
E
V
P
E
I
G
E
E
V
I
E
I
K
A
A
A
R
D
P
G
S
R
A
K
I
A
V
K
T
N
D
K
R
I
D
P
V
G
A
C
V
G
M
R
G
A
R
V
Q
A
V
S
T
E
L
G
G
E
R
I
D
I
V
L
W
D
D
N
P
A
Q
F
V
I
N
A
M
-
A
P
A
D
V
A
S
I
-
V
V
D
-
E
--
D
K
H
T
M
D
I
A
V
E
A
G
N
L
A
Q
A
I
G
R
N
G
Q
N
V
R
L
A
S
Q
L
S
G
W
E
L
N
V
-
M
T
V
D
D
L
-----------------------------------------------------------------------------------------------------
18
Fugue
68.18
38%
38
- C7 -
-
4MTN
-
?
A:
[5-406]
-
G
N
E
V
L
R
I
V
D
S
I
H
R
D
K
S
I
D
K
E
I
V
F
E
G
V
E
Q
A
I
L
S
A
A
R
K
H
F
G
E
E
E
V
I
E
V
H
I
D
R
T
S
G
Q
P
M
V
K
T
N
-
G
R
E
I
D
R
D
E
L
G
D
I
L
G
-----------------------------
R
I
S
A
Q
T
K
Q
--
V
M
I
Q
K
I
R
E
A
E
R
D
T
L
F
D
E
Y
A
Q
L
R
G
Q
I
V
S
G
T
V
T
R
N
E
G
S
----
A
I
T
V
N
I
G
----
K
----
A
E
A
I
L
P
R
-
S
E
M
I
P
G
E
S
H
R
P
N
E
R
I
R
A
V
V
L
E
V
K
K
M
G
P
R
-
V
R
V
V
L
S
R
A
H
P
D
F
V
R
R
L
L
E
L
E
I
P
E
V
N
E
R
I
I
E
I
R
S
L
A
R
E
A
G
Y
R
T
K
V
A
V
S
C
A
D
S
N
I
D
P
V
G
A
C
V
G
V
R
G
A
R
I
R
N
V
G
E
E
L
G
G
E
R
I
E
V
V
R
W
N
D
S
L
Q
V
L
V
P
N
A
-
M
Q
P
S
E
V
E
D
V
-
I
L
C
-
P
M
L
G
--
R
V
L
V
L
V
R
D
D
Q
L
S
L
A
I
G
K
R
G
Q
N
V
R
L
A
S
K
L
V
G
W
D
I
D
V
M
T
R
E
E
L
D
Q
Q
L
D
Q
----
A
V
V
A
Y
S
Q
IPGV
S
E
E
L
A
E
G
L
V
S
Q
G
F
L
S
F
E
D
----------
L
S
V
I
E
P
D
E
L
M
E
M
G
S
L
T
Q
E
Q
A
D
V
I
V
E
Y
A
E
R
E
S
E
R
I
E
K
E
Q
D
L
R
R
A
T
E
K
A
ERQSQE
6
PsiBlast_PDB
62.06
42%
10
- C7 -
-
5LM9
-
NUSA_ECOLI
A:
[5-247]
-------------------------------------------------------------------------------------------------------
F
D
R
I
T
T
Q
T
A
K
Q
V
I
-
V
Q
K
V
R
E
A
E
R
A
M
V
V
D
Q
F
R
E
H
E
G
E
I
I
T
G
V
V
K
K
V
N
R
D
----
N
I
S
L
D
L
G
----
N
N---
A
E
A
V
I
L
R
E
D
M
-
L
P
R
E
N
F
R
P
G
D
R
V
R
G
V
L
Y
S
V
R
P
-
E
A
R
G
A
Q
L
F
V
T
R
S
K
P
E
M
L
I
E
L
F
R
I
E
V
P
E
I
G
E
E
V
I
E
I
K
A
A
A
R
D
P
G
S
R
A
K
I
A
V
K
T
N
D
K
R
I
D
P
V
G
A
C
V
G
M
R
G
A
R
V
Q
A
V
S
T
E
L
G
G
E
R
I
D
I
V
L
W
D
D
N
P
A
Q
F
V
I
N
A
M
-
A
P
A
D
V
A
S
I
-
V
V
D
-
E
--
D
K
H
T
M
D
I
A
V
E
A
G
N
L
A
Q
A
I
G
R
N
G
Q
N
V
R
L
A
S
Q
L
S
G
W
E
L
N
V
-
M
T
V
D
D
L
-----------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
57.09
62%
-116
- C7 -
-
2MT4
-
NUSA_BACSU
A:
[1-123]
M
S
S
E
L
L
D
A
L
T
I
L
E
K
E
K
G
I
S
K
E
I
I
I
E
A
I
E
A
A
L
I
S
A
Y
K
R
N
F
N
Q
A
Q
N
V
R
V
D
L
N
R
E
T
G
S
I
-
R
V
F
A
-
R
K
D
V
V
D
E
V
Y
D
Q
R
L
E
I
S
I
E
E
A
Q
G
I
H
P
E
Y
M
V
G
D
V
V
E
I
E
V
T
P
K
D
F
G
R
I
A
A
Q
T
A
K
Q
V
V
-
T
Q
R
V
R
E
A
E
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
56.86
48%
39
- C7 -
-
2ASB
1
NUSA_MYCTU
A:
[4-229]
-------------------------------------------------------------------------------------------------------------------------------------
S
T
R
E
G
E
I
V
A
G
V
I
Q
R
D
S
R
A
N
A
R
G
L
V
V
V
R
I
G
T
E
T
K
A
----
S
E
G
V
I
P
A
A
E
Q
-
V
P
G
E
S
Y
E
H
G
N
R
L
R
C
Y
V
V
G
V
T
R
-
G
A
R
E
P
L
I
T
L
S
R
T
H
P
N
L
V
R
K
L
F
S
L
E
V
P
E
I
A
D
G
S
V
E
I
V
A
V
A
R
E
A
G
H
R
S
K
I
A
V
R
S
N
V
A
G
L
N
A
K
G
A
C
I
G
P
M
G
Q
R
V
R
N
V
M
S
E
L
S
G
E
K
I
D
I
I
D
Y
D
D
D
P
A
R
F
V
A
N
A
L
-
S
P
A
K
V
V
S
V
-
S
V
I
D
Q
-
T
-
A
R
A
A
R
V
V
V
P
D
F
Q
L
S
L
A
I
G
K
E
G
Q
N
A
R
L
A
A
R
L
T
G
W
R
I
D
I
-
R
G
D
A
P
P
P
P
P
G
-------------------------------------------------------------------------------------------------
30
HHSearch
56.01
62%
-116
- C7 -
-
2MT4
-
NUSA_BACSU
A:
[1-124]
M
S
S
E
L
L
D
A
L
T
I
L
E
K
E
K
G
I
S
K
E
I
I
I
E
A
I
E
A
A
L
I
S
A
Y
K
R
N
F
N
Q
A
Q
N
V
R
V
D
L
N
R
E
T
G
S
I
-
R
V
F
A
-
R
K
D
V
V
D
E
V
Y
D
Q
R
L
E
I
S
I
E
E
A
Q
G
I
H
P
E
Y
M
V
G
D
V
V
E
I
E
V
T
P
K
D
F
G
R
I
A
A
Q
T
A
K
Q
V
V
-
T
Q
R
V
R
E
A
E
R
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_CBE
54.87
47%
54
- C7 -
-
2ATW
1
NUSA_MYCTU
C:
[1-223]
----------------------------------------------------------------------------------------------------------------------------------
G
E
F
S
T
R
E
G
E
I
V
A
G
V
I
Q
R
D
S
R
A
NARG
L
V
V
V
R
I
G
----
T
ETKA
S
E
G
V
I
P
A
A
E
Q
-
V
P
G
E
S
Y
E
H
G
N
R
L
R
C
Y
V
V
G
V
T
R
-
G
A
R
E
P
L
I
T
L
S
R
T
H
P
N
L
V
R
K
L
F
S
L
E
V
P
E
I
A
D
G
S
V
E
I
V
A
V
A
R
E
A
G
H
R
S
K
I
A
V
R
S
N
V
A
G
L
N
A
K
G
A
C
I
G
P
M
G
Q
R
V
R
N
V
M
S
E
L
S
G
E
K
I
D
I
I
D
Y
D
D
D
P
A
R
F
V
A
N
A
L
-
S
P
A
K
V
V
S
V
-
S
V
I
-
D
-
Q
T
A
R
A
A
R
V
V
V
P
D
F
Q
L
S
L
A
I
G
K
E
G
Q
N
A
R
L
A
A
R
L
T
G
W
R
I
D
I
-
R
G
D
A
-------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
53.61
47%
57
- C7 -
-
2ASB
1
NUSA_MYCTU
A:
[4-223]
-------------------------------------------------------------------------------------------------------------------------------------
S
T
R
E
G
E
I
V
A
G
V
I
Q
R
D
S
R
A
N
A
R
G
L
V
V
V
R
I
G
----
T
E
T
K
A
S
E
G
V
I
P
A
A
E
Q
-
V
P
G
E
S
Y
E
H
G
N
R
L
R
C
Y
V
V
G
V
T
R
-
G
A
R
E
P
L
I
T
L
S
R
T
H
P
N
L
V
R
K
L
F
S
L
E
V
P
E
I
A
D
G
S
V
E
I
V
A
V
A
R
E
A
G
H
R
S
K
I
A
V
R
S
N
V
A
G
L
N
A
K
G
A
C
I
G
P
M
G
Q
R
V
R
N
V
M
S
E
L
S
G
E
K
I
D
I
I
D
Y
D
D
D
P
A
R
F
V
A
N
A
L
-
S
P
A
K
V
V
S
V
-
S
V
I
-
D
-
Q
T
A
R
A
A
R
V
V
V
P
D
F
Q
L
S
L
A
I
G
K
E
G
Q
N
A
R
L
A
A
R
L
T
G
W
R
I
D
I
-
R
G
D
A
-------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
52.66
47%
51
- C7 -
-
2ATW
1
NUSA_MYCTU
A:
[3-223]
------------------------------------------------------------------------------------------------------------------------------------
F
S
T
R
E
G
E
I
V
A
G
V
I
Q
R
D
S
R
A
N
A
R
G
L
V
V
V
R
I
G
----
T
ET
K
A
S
E
G
V
I
P
A
A
E
Q
-
V
P
G
E
S
Y
E
H
G
N
R
L
R
C
Y
V
V
G
V
T
R
-
G
A
R
E
P
L
I
T
L
S
R
T
H
P
N
L
V
R
K
L
F
S
L
E
V
P
E
I
A
D
G
S
V
E
I
V
A
V
A
R
E
A
G
H
R
S
K
I
A
V
R
S
N
V
A
G
L
N
A
K
G
A
C
I
G
P
M
G
Q
R
V
R
N
V
M
S
E
L
S
G
E
K
I
D
I
I
D
Y
D
D
D
P
A
R
F
V
A
N
A
L
-
S
P
A
K
V
V
S
V
-
S
V
I
-
D
-
Q
T
A
R
A
A
R
V
V
V
P
D
F
Q
L
S
L
A
I
G
K
E
G
Q
N
A
R
L
A
A
R
L
T
G
W
R
I
D
I
-
R
G
D
A
-------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
46.16
37%
-62
- C7 -
-
2KWP
-
NUSA_ECOLI
A:
[1-126]
M
N
K
E
I
L
A
V
V
E
A
V
S
N
E
K
A
L
P
R
E
K
I
F
E
A
L
E
S
A
L
A
T
A
T
K
K
K
Y
E
Q
E
I
D
V
R
V
Q
I
D
R
K
S
G
D
F
-
D
T
F
R
-
R
W
L
V
V
D
E
V
T
Q
P
T
K
E
I
T
L
E
A
A
R
Y
E
D
E
S
L
N
L
G
D
Y
V
E
D
Q
I
E
S
V
T
F
D
R
I
T
T
Q
T
A
K
Q
V
I
-
V
Q
K
V
R
E
A
E
R
A
M
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
40.55
20%
-125
- C7 -
-
2CY1
-
?
A:
[7-137]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
L
E
E
L
R
Y
I
S
-
V
F
-----
H
S
I
T
G
V
T
A
Y
R
C
I
V
D
E
E
N
N
R
L
I
F
L
V
S
E
G
E
-----
A
G
R
A
I
G
R
G
G
R
L
I
K
L
L
R
E
A
L
-
G
K
N
I
E
V
V
E
Y
S
S
D
L
E
R
I
V
K
N
L
F
-
P
G
V
K
I
E
S
I
-
N
V
R
-
E
R
N
G
V
K
Q
V
V
I
K
V
S
E
D
D
K
G
A
A
I
G
K
G
G
K
N
V
K
R
A
R
L
V
L
S
K
L
F
G
-------------------------------------------------------------------------------------------------------------
23
Fugue
40.35
37%
-117
* C6 *
-
1F93
-
HNF1A_MOUSE
F:
[5-31]
-
L
S
Q
L
Q
T
E
L
L
A
A
L
L
E
S
G
L
S
K
E
A
L
I
Q
A
L
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
39.71
20%
-106
- C7 -
-
2CXC
-
?
A:
[7-137]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
L
E
E
L
R
Y
I
S
-
V
F
-----
H
S
I
T
G
V
T
A
Y
R
C
I
V
D
E
E
N
N
R
L
I
F
L
V
S
E
G
E
-----
A
G
R
A
I
G
R
G
G
R
L
I
K
L
L
R
E
A
L
-
G
K
N
I
E
V
V
E
Y
S
S
D
L
E
R
I
V
K
N
L
F
-
P
G
V
K
I
E
S
I
-
N
V
R
-
E
R
N
G
V
K
Q
V
V
I
K
V
S
E
D
D
K
G
A
A
I
G
K
G
G
K
N
V
K
R
A
R
L
V
L
S
K
L
F
G
-------------------------------------------------------------------------------------------------------------