@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : CDK8_HUMAN: (2013-07-19 )
MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY

Atome Classification :

(102 SA) .........10........20........30........40........50...----.....----60---.........70........80.......----.90--.........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......-----------230.......--240.......250.......260.......270.......280.......290.......300..--.....310.......320.......330...--....340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460..
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGI----S----MSACREIALLRELKHPNVISLQKVFLSH----AD---RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLT-----------SEPIFHCRQE--DIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKP--DSKAFHLLQKLLTMDPIKRITSEQAMQDPYF--LEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY
2 PsiBlast_PDB 94.84100%-126 - C1 -4F6S CDK8_HUMAN A:[3-361] MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGI----S----MSACREIALLRELKHPNVISLQKVFLSH----AD---RKVWLLFDYAEHDLWHIIKFHRAS--------LPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFA-----------------VTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLT-----------SEPIFHCR---------NPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKP--DSKAFHLLQKLLTMDPIKRITSEQAMQDPYF--LEDPLPTSDVFAGCQIPYPKREFL---------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 94.20100%-122 - C1 -4F6W CDK8_HUMAN A:[3-361] MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGI----S----MSACREIALLRELKHPNVISLQKVFLSH----AD---RKVWLLFDYAEHDLWHIIKFHRASK-----VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFA------------------TFWYRAPELLLGARHYTKAIDIWAIGCIFAELLT-----------SEPIFHCRQ--------NPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKP--DSKAFHLLQKLLTMDPIKRITSEQAMQDPYF--LEDPLPTSDVFAGCQIPYPKREFL---------------------------------------------------------------------------------------------------------
8 PsiBlast_PDB 94.16100%-127 - C1 -4F7N CDK8_HUMAN A:[3-363] MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGI----S----MSACREIALLRELKHPNVISLQKVFLSH----AD---RKVWLLFDYAEHDLWHIIKFHRAS------VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGF-----------------VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLT-----------SEPIFHCRQE-------NPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKP--DSKAFHLLQKLLTMDPIKRITSEQAMQDPYF--LEDPLPTSDVFAGCQIPYPKREFLTE-------------------------------------------------------------------------------------------------------
5 PsiBlast_PDB 93.89100%-128 - C1 -4F70 CDK8_HUMAN A:[3-361] MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGI----S----MSACREIALLRELKHPNVISLQKVFLSH----AD---RKVWLLFDYAEHDLWHIIKFHRASKA------LPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADM--------------------VTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLT-----------SEPIFHCR---------NPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKP--DSKAFHLLQKLLTMDPIKRITSEQAMQDPYF--LEDPLPTSDVFAGCQIPYPKREFL---------------------------------------------------------------------------------------------------------
110 HHSearch 93.74100%-123 - C1 -4F6U CDK8_HUMAN A:[3-361] MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGI----S----MSACREIALLRELKHPNVISLQKVFLSH----AD---RKVWLLFDYAEHDLWHIIKFHRASK-----VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGF-----------------VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLT-----------SEPIFHCRQE-------NPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKP--DSKAFHLLQKLLTMDPIKRITSEQAMQDPYF--LEDPLPTSDVFAGCQIPYPKREFL---------------------------------------------------------------------------------------------------------
9 PsiBlast_PDB 93.14100%-124 - C1 -4F7S CDK8_HUMAN A:[3-361] MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGI----S----MSACREIALLRELKHPNVISLQKVFLSH----AD---RKVWLLFDYAEHDLWHIIKFHRASK------QLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKP---------TFWYRAPELLLGARHYTKAIDIWAIGCIFAELLT-----------SEPIFHCR-------TSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKP--DSKAFHLLQKLLTMDPIKRITSEQAMQDPYF--LEDPLPTSDVFAGCQIPYPKREFL---------------------------------------------------------------------------------------------------------
1 PsiBlast_PDB 91.98100%-132 - C1 -3RGF CDK8_HUMAN A:[3-355] MDYDFKVKLSSERERVEDLFEYEGCKVG-----HVYKAKRKDGKDDKDYALKQI----EGTGI----S----MSACREIALLRELKHPNVISLQKVFLSH----AD---RKVWLLFDYAEHDLWHIIKFHRASK-------LPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFAR----------------VTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLT-----------SEPIFHCRQ--------NPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKP--DSKAFHLLQKLLTMDPIKRITSEQAMQDPYF--LEDPLPTSDVFAGCQIPY---------------------------------------------------------------------------------------------------------------
6 PsiBlast_PDB 91.90100%-126 - C1 -4F7J CDK8_HUMAN A:[3-361] MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGI----S----MSACREIALLRELKHPNVISLQKVFLSH----AD---RKVWLLFDYAEHDLWHIIKFHR---------QLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGF------------------VTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLT-----------SEPIFHCRQ--------NPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKP--DSKAFHLLQKLLTMDPIKRITSEQAMQDPYF--LEDPLPTSDVFAGCQIPYPKREFL---------------------------------------------------------------------------------------------------------
7 PsiBlast_PDB 91.62100%-124 - C1 -4F7L CDK8_HUMAN A:[3-361] MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQI----EGTGI----S----MSACREIALLRELKHPNVISLQKVFLSH----AD---RKVWLLFDYAEHDLWHIIKFHRAS-------QLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMG--------------------TFWYRAPELLLGARHYTKAIDIWAIGCIFAELLT-----------SEPIFHCRQ--------NPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKP--DSKAFHLLQKLLTMDPIKRITSEQAMQDPYF--LEDPLPTSDVFAGCQIPYPKREFL---------------------------------------------------------------------------------------------------------
27 PsiBlast_CBE 62.3738%-108 - C1 -3S00 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
68 PsiBlast_CBE 62.3438%-107 - C1 -3R1S CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
65 PsiBlast_CBE 62.2138%-108 - C1 -3R6X CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
57 PsiBlast_CBE 61.8638%-107 - C1 -3R83 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
52 PsiBlast_CBE 61.3538%-106 - C1 -3R8V CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
53 PsiBlast_CBE 61.2238%-103 - C1 -3R8U CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
67 PsiBlast_CBE 61.0238%-105 - C1 -3R1Y CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
92 PsiBlast_CBE 61.0138%-103 - C1 -3QQJ CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
63 PsiBlast_CBE 60.9838%-108 - C1 -3R73 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
45 PsiBlast_CBE 60.9438%-107 - C1 -3RAI CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
19 PsiBlast_PDB 60.9138%-107 - C1 -3QQF CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
71 PsiBlast_CBE 60.8838%-107 - C1 -3QZH CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
66 PsiBlast_CBE 60.8638%-104 - C1 -3R28 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
33 PsiBlast_CBE 60.8538%-107 - C1 -3ROY CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
42 PsiBlast_CBE 60.7738%-107 - C1 -3RJC CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
54 PsiBlast_CBE 60.7338%-108 - C1 -3R8P CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
36 PsiBlast_CBE 60.7338%-107 - C1 -3RM7 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
93 PsiBlast_CBE 60.5938%-105 - C1 -3QQH CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
72 PsiBlast_CBE 60.5538%-105 - C1 -3QZG CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
97 PsiBlast_CBE 60.5438%-106 - C1 -3PJ8 CDK2_HUMAN A:[10-295] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR---ETEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGV-----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
59 PsiBlast_CBE 60.5338%-107 - C1 -3R7V CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
117 HHSearch 60.4936%-108 - C1 -3N9X ? A:[20-383] -----------KNVHVPDNYIIKH-LIGRGSYGYVYLAYDKN--TEKNVAIKKV----NRMFE----DLIDCKRILREITILNRLKSDYIIRLYDLIIPD----DLLKFDELYIVLEIADSDLKKLFKTPI---------FLTEEHIKTILYNLLLGENFIHESGIIHRDLKPANCLLNQD----CSVKVCDFGLARTI------------HVVTRWYRAPELILLQENYTKSIDIWSTGCIFAELLNMLQSHINDPTNRFPLFPGSSCFP----HEKSNRDQLNIIFNIIGTPTEDDLKNINKP-EVIKYIKLFPHR--KPINLKQKY----PSI--SDDGINLLESMLKFNPNKRITIDQALDHPYL--KDVRKKKLE---TKKIIL---------------------------------------------------------------------------------------------------------------
77 PsiBlast_CBE 60.4138%-105 - C1 -3QX2 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
100 PsiBlast_CBE 60.3638%-107 - C1 -2WPA CDK2_HUMAN C:[14-299] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDLK---KFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
70 PsiBlast_CBE 60.3538%-106 - C1 -3QZI CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
64 PsiBlast_CBE 60.3438%-109 - C1 -3R71 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
11 PsiBlast_PDB 60.1338%-103 - C1 -3PXF CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
20 PsiBlast_PDB 60.0938%-104 - C1 -3QQG CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
21 PsiBlast_CBE 59.9338%-109 - C1 -4GCJ CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
58 PsiBlast_CBE 59.9238%-106 - C1 -3R7Y CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
87 PsiBlast_CBE 59.9038%-104 - C1 -3QTQ CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
73 PsiBlast_CBE 59.9038%-106 - C1 -3QZF CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
62 PsiBlast_CBE 59.8438%-108 - C1 -3R7E CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
75 PsiBlast_CBE 59.6938%-105 - C1 -3QXO CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
14 PsiBlast_PDB 59.6238%-102 - C1 -3PXY CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
98 PsiBlast_CBE 59.6038%-108 - C1 -2WXV CDK2_HUMAN C:[14-299] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDLK---KFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
16 PsiBlast_PDB 59.5938%-105 - C1 -3PY0 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
56 PsiBlast_CBE 59.4938%-107 - C1 -3R8L CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
69 PsiBlast_CBE 59.3438%-106 - C1 -3R1Q CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
85 PsiBlast_CBE 59.2838%-108 - C1 -3QTS CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR------------P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGV-----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
40 PsiBlast_CBE 59.1538%-102 - C1 -3RK7 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
90 PsiBlast_CBE 59.1038%-106 - C1 -3QQL CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
18 PsiBlast_PDB 59.0738%-105 - C1 -3QL8 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
23 PsiBlast_CBE 58.9338%-105 - C1 -4EZ3 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
41 PsiBlast_CBE 58.9038%-106 - C1 -3RK5 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
32 PsiBlast_CBE 58.8938%-105 - C1 -3RPO CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
15 PsiBlast_PDB 58.8438%-104 - C1 -3PXZ CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
82 PsiBlast_CBE 58.5738%-102 - C1 -3QTX CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
49 PsiBlast_CBE 58.3638%-107 - C1 -3R9H CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
61 PsiBlast_CBE 58.1638%-105 - C1 -3R7I CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR------------P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGV-----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
48 PsiBlast_CBE 58.1638%-106 - C1 -3R9N CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR------------P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGV-----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
60 PsiBlast_CBE 58.1338%-107 - C1 -3R7U CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR------------P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGV-----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
39 PsiBlast_CBE 58.0038%-101 - C1 -3RK9 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
91 PsiBlast_CBE 57.8638%-102 - C1 -3QQK CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
78 PsiBlast_CBE 57.8438%-103 - C1 -3QWK CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
34 PsiBlast_CBE 57.8338%-104 - C1 -3RNI CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
31 PsiBlast_CBE 57.7638%-108 - C1 -3RPR CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR------------P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGV-----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
99 PsiBlast_CBE 57.7038%-104 - C1 -2WXV CDK2_HUMAN A:[14-299] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDLK---KFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
51 PsiBlast_CBE 57.7038%-107 - C1 -3R8Z CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVP----TH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
76 PsiBlast_CBE 57.6738%-108 - C1 -3QX4 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
88 PsiBlast_CBE 57.5338%-100 - C1 -3QRU CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIRL---TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
30 PsiBlast_CBE 57.5138%-102 - C1 -3RPV CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
26 PsiBlast_CBE 57.5038%-105 - C1 -3S0O CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIRL---TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADF--ARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
46 PsiBlast_CBE 57.3538%-106 - C1 -3RAH CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR------------P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGV-----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
50 PsiBlast_CBE 57.3338%-102 - C1 -3R9D CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
80 PsiBlast_CBE 57.2938%-101 - C1 -3QU0 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
81 PsiBlast_CBE 57.1038%-105 - C1 -3QTZ CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
79 PsiBlast_CBE 56.8138%-103 - C1 -3QWJ CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
74 PsiBlast_CBE 56.6938%-104 - C1 -3QXP CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
22 PsiBlast_CBE 56.6438% -96 - C1 -4EZ7 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
37 PsiBlast_CBE 56.5838%-102 - C1 -3RM6 CDK2_HUMAN A:[17-302] -------------------------KIGEGT-GVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
12 PsiBlast_PDB 56.4338% -99 - C1 -3PXQ CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
89 PsiBlast_CBE 56.0638%-100 - C1 -3QRT CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
24 PsiBlast_CBE 55.8138% -99 - C1 -3SQQ CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLAR------RTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
38 PsiBlast_CBE 55.7038%-103 - C1 -3RKB CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
86 PsiBlast_CBE 55.6738%-102 - C1 -3QTR CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR------------P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGV-----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
17 PsiBlast_PDB 55.4538% -96 - C1 -3PY1 CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
84 PsiBlast_CBE 55.4038%-102 - C1 -3QTU CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
29 PsiBlast_CBE 55.3538%-107 - C1 -3RPY CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR------------P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLA----------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
96 PsiBlast_CBE 55.1738%-108 - C1 -1OIT CDK2_HUMAN A:[9-294] -------------------------KIGEGTYGVVYKARNK--L-GEVVALKKI-------------------TAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLSFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARA--------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
128 HHSearch 55.1339%-112 - C1 -3NIZ ? A:[15-307] -----------YFQGLMEKYQKLE-KVGEGTYGVVYKAKDSQ---GRIVALKRI----R--GI----P----STAIREISLLKELHHPNIVSLIDVIHS------E---RCLTLVFEFMEKDLKKVLDENK----T----GLQDSQIKIYLYQLLRGVAHCHQHRILHRDLKPQNLLINSD----GALKLADFGLARAFGIPVR------HEVVTLWYRAPDVLMGSKKYSTSVDIWSIGCIFAEMIT-----------GKPLFPGVT-----------DDDQLPKIFSILGTPNPREWPQVQELPLWKQRTF----QVFEKKPWSSII----PGF--CQEGIDLLSNMLCFDPNKRISARDAMNHPYF--KDL------------------------------------------------------------------------------------------------------------------------------
55 PsiBlast_CBE 55.0238%-102 - C1 -3R8M CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFG-----------EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
94 PsiBlast_CBE 54.4338%-104 - C1 -3EZV CDK2_HUMAN A:[11-296] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR-------V----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGL-----------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
83 PsiBlast_CBE 54.4038% -97 - C1 -3QTW CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGV----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
47 PsiBlast_CBE 54.2738%-102 - C1 -3R9O CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR------------P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGV-----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
44 PsiBlast_CBE 54.2638%-107 - C1 -3RAK CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR------------P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLA----------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
43 PsiBlast_CBE 54.2338%-107 - C1 -3RAL CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR------------P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLA----------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
35 PsiBlast_CBE 53.9038%-104 - C1 -3RMF CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIRL-----------P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLA----------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
25 PsiBlast_CBE 53.6438%-105 - C1 -3S1H CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR------------P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLA----------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
95 PsiBlast_CBE 52.5238%-103 - C1 -3EZR CDK2_HUMAN A:[11-296] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR-------V----P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADF---------------------TLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
28 PsiBlast_CBE 52.3138%-104 - C1 -3RZB CDK2_HUMAN A:[17-302] -------------------------KIGEGTYGVVYKARNK--LTGEVVALKKIR------------P----STAIREISLLKELNHPNIVKLLDVI--H----TE---NKLYLVFEFLHQDL---KKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA----IKLADFGLARAFGV-----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-----------RRALFPGDSE--I---------DQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFS-----------KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP---------------------------------------------------------------------------------------------------------------------------
114 HHSearch 45.7333%-100 - C1 -3ZDU CDKL3_HUMAN A:[2-292] ----------------MEMYETLG-KVGEGSYGTVMKCKHKN--TGQIVAIKIF----Y--------N----KIAMREIKFLKQFHHENLVNLIEVFRQ------K---KKIHLVFEFIDHTVLDELQHYC----H----GLESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQS----GITKLCDFGFART-----DIY---DDEVATRWYRAPELVLKDTSYGKPVDIWALGCMIIEMAT-----------GNPYLPSSS-----------DLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLP--QV-QHPKNARKKY----PKL--NGLLADIVHACLQIDPADRISSSDLLHHEYF--TRDGF----------------------------------------------------------------------------------------------------------------------------
130 HHSearch 43.2435%-110 - C1 -2FST MK14_HUMAN X:[23-323] -----------TIWEVPERYQNLS-PVG----GSVCAAFDTK--TGLRVAVKKL----SRPFQSIIHA----KRTYRELRLLKHMKHENVIGLLDVFTPARSLEEF---NDVYLVTHLMGADLN-----Q----------KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNED----CELKILD---------------------ATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLT-----------GRTLFPGTD-----------HIDQLKLILRLVGTPGAELLKKISSESA-RNYIQSLT--QMPKMNFANVF----IGA--NPLAVDLLEKMLVLDSDKRITAAQALAHAYF--AQYHDPDD-------------------------------------------------------------------------------------------------------------------------