@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu03460: (2016-06-05 )
MELQLALDLVNIPEAIELVKEVEQYIDVVEIGTPVVINEGLRAVKEIKEAFPQLKVLADLKIMDAGGYEIMKASEAGADIITVLGATDDATIKGAVEEAKKQKKKILVDMINVKDIESRAKEIDALGVDYICVHTGYDLQAEGKNSFEELTTIKNTVKNAKTAIAGGIKLDTLPEVIQQKPDLVIVGGGITSAADKAETASKMKQLIVQG
Atome Classification :
(38 SA)
-.........10........20........30........40........50........60........70........80........90........100.......110.....-..120.......130.......140.----.-.-.-..-.150...-..-.-.160--.......170.......180.......190.......200.......210
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-M
E
L
Q
L
A
L
D
LVN
I
P
E
A
I
E
L
V
K
E
V
E
Q
Y
I
D
V
V
EIGT
P
V
V
I
N
E
G
L
R
A
V
K
E
I
K
E
A
F
P
Q
L
K
V
L
A
D
L
K
I
MDAGG
Y
E
I
M
KASEAGA
D
I
I
T
V
LGATDD
A
T
I
K
G
A
V
E
E
A
K
K
Q
K
K
K
I
L
V
D
M
I
N
V
K
D
I
E
-
S
R
A
K
E
I
D
ALGV
D
Y
I
C
V
HTGYDLQAEG----K-N-
S
-
F
E
-
E
L
T
T
I
K
N
-
T
V
-
K
-
N
A
K
T
--AIAGGIKLD
T
L
P
E
V
I
QQKP
D
L
V
I
VGGGITSA
A
D
K
A
E
T
A
S
K
M
K
Q
L
IVQG-
1
PsiBlast_PDB
87.90
44%
-123
- C1 -
3F4W
1
?
A:
[1-209]
-
M
K
L
Q
L
A
L
D
E
L
T
L
P
E
A
M
V
F
M
D
K
V
V
D
D
V
D
I
I
E
V
G
T
P
F
L
I
R
E
G
V
N
A
I
K
A
I
K
E
K
Y
P
H
K
E
V
L
A
D
A
K
I
M
D
G
G
H
F
E
S
Q
L
L
F
D
A
G
A
D
Y
V
T
V
L
G
V
T
D
V
L
T
I
Q
S
C
I
R
A
A
K
E
A
G
K
Q
V
V
V
D
M
I
C
V
D
D
L
P
-
A
R
V
R
L
L
E
E
A
G
A
D
M
L
A
V
H
T
G
T
D
Q
Q
A
A
G
----
R
-
K
-
P
-
I
D
-
D
L
I
T
M
L
K
-
V
R
-
R
-
K
A
R
I
--
A
V
A
G
G
I
S
S
Q
T
V
K
D
Y
A
L
L
G
P
D
V
V
I
V
G
S
A
I
T
H
A
A
D
P
A
G
E
A
R
K
I
S
Q
V
L
L
Q
--
21
PsiBlast_CBE
86.59
44%
-119
- C1 -
3F4W
1
?
B:
[1-209]
-
M
K
L
Q
L
A
L
D
E
L
T
L
P
E
A
M
V
F
M
D
K
V
V
D
D
V
D
I
I
E
V
G
T
P
F
L
I
R
E
G
V
N
A
I
K
A
I
K
E
K
Y
P
H
K
E
V
L
A
D
A
K
I
M
D
G
G
H
F
E
S
Q
L
L
F
D
A
G
A
D
Y
V
T
V
L
G
V
T
D
V
L
T
I
Q
S
C
I
R
A
A
K
E
A
G
K
Q
V
V
V
D
M
I
C
V
D
D
L
P
-
A
R
V
R
L
L
E
E
A
G
A
D
M
L
A
V
H
T
G
T
D
Q
Q
A
A
G
----
R
-
K
-
P
-
I
D
-
D
L
I
T
M
L
K
-
V
R
-
R
-
K
A
R
I
--
A
V
A
G
G
I
S
S
Q
T
V
K
D
Y
A
L
L
G
P
D
V
V
I
V
G
S
A
I
T
H
A
A
D
P
A
G
E
A
R
K
I
S
Q
V
L
L
Q
--
115
HHSearch
75.00
43%
-112
- C1 -
3F4W
1
?
A:
[1-209]
-
M
K
L
Q
L
A
L
D
E
L
T
L
P
E
A
M
V
F
M
D
K
V
V
D
D
V
D
I
I
E
V
G
T
P
F
L
I
R
E
G
V
N
A
I
K
A
I
K
E
K
Y
P
H
K
E
V
L
A
D
A
K
I
M
D
G
G
H
F
E
S
Q
L
L
F
D
A
G
A
D
Y
V
T
V
L
G
V
T
D
V
L
T
I
Q
S
C
I
R
A
A
K
E
A
G
K
Q
V
V
V
D
-
M
I
C
V
D
D
L
P
A
R
V
R
L
L
E
E
A
G
A
D
M
L
A
V
H
T
G
T
D
Q
Q
A
A
G
----
R
-
K
-
P
I
D
D
-
L
I
T
M
L
K
V
--
R
-
R
-
K
A
R
I
--
A
V
A
G
G
I
S
S
Q
T
V
K
D
Y
A
L
L
G
P
D
V
V
I
V
G
S
A
I
T
H
A
A
D
P
A
G
E
A
R
K
I
S
Q
V
L
L
Q
--
113
HHSearch
73.24
39%
-113
- C1 -
3AJX
3
HPS_MYCGS
A:
[1-207]
-
M
K
L
Q
V
A
I
D
L
L
S
T
E
A
A
L
E
L
A
G
K
V
A
E
Y
V
D
I
I
E
L
G
T
P
L
I
K
A
E
G
L
S
V
I
T
A
V
K
K
A
H
P
D
K
I
V
F
A
D
M
K
T
M
D
A
G
E
L
E
A
D
I
A
F
K
A
G
A
D
L
V
T
V
L
G
S
A
D
D
S
T
I
A
G
A
V
K
A
A
Q
A
H
N
K
G
V
V
V
D
L
I
G
I
E
D
K
A
-
T
R
A
Q
E
V
R
A
L
G
A
K
F
V
E
M
H
A
G
L
D
E
Q
A
K
P
----
G
-
F
-
D
-
L
N
-
G
L
L
A
A
G
E
-
K
--
A
-
R
V
P
F
--
S
V
A
G
G
V
K
V
A
T
I
P
A
V
Q
K
A
G
A
E
V
A
V
A
G
G
A
I
Y
G
A
A
D
P
A
A
A
A
K
E
L
R
A
A
I
A
---
22
PsiBlast_CBE
71.47
40%
-120
- C1 -
3AJX
3
HPS_MYCGS
D:
[1-189]
-
M
K
L
Q
V
A
I
D
L
L
S
T
E
A
A
L
E
L
A
G
K
V
A
E
Y
V
D
I
I
E
L
G
T
P
L
I
K
A
E
G
L
S
V
I
T
A
V
K
K
A
H
P
D
K
I
V
F
A
D
M
K
T
M
D
A
G
E
L
E
A
D
I
A
F
K
A
G
A
D
L
V
T
V
L
G
S
A
D
D
S
T
I
A
G
A
V
K
A
A
Q
A
H
N
K
G
V
V
V
D
L
I
G
I
E
D
K
A
-
T
R
A
Q
E
V
R
A
L
G
A
K
F
V
E
M
H
A
G
L
D
E
Q
A
------
K
-
P
-
G
-
F
--
D
L
N
G
L
L
A
-
A
G
-
E
-
K
A
R
V
PF
S
V
A
G
G
V
K
V
A
T
I
P
A
V
Q
K
A
G
A
E
V
A
V
A
G
G
A
I
---------------------
24
PsiBlast_CBE
70.07
40%
-119
- C1 -
3AJX
2
HPS_MYCGS
B:
[1-189]
-
M
K
L
Q
V
A
I
D
L
L
S
T
E
A
A
L
E
L
A
G
K
V
A
E
Y
V
D
I
I
E
L
G
T
P
L
I
K
A
E
G
L
S
V
I
T
A
V
K
K
A
H
P
D
K
I
V
F
A
D
M
K
T
M
D
A
G
E
L
E
A
D
I
A
F
K
A
G
A
D
L
V
T
V
L
G
S
A
D
D
S
T
I
A
G
A
V
K
A
A
Q
A
H
N
K
G
V
V
V
D
L
I
G
I
E
D
K
A
-
T
R
A
Q
E
V
R
A
L
G
A
K
F
V
E
M
H
A
G
L
D
E
Q
A
------
K
-
P
-
G
-
F
--
D
L
N
G
L
L
A
-
A
G
-
E
-
K
A
R
V
PF
S
V
A
G
G
V
K
V
A
T
I
P
A
V
Q
K
A
G
A
E
V
A
V
A
G
G
A
I
---------------------
23
PsiBlast_CBE
69.86
40%
-118
- C1 -
3AJX
4
HPS_MYCGS
C:
[1-189]
-
M
K
L
Q
V
A
I
D
L
L
S
T
E
A
A
L
E
L
A
G
K
V
A
E
Y
V
D
I
I
E
L
G
T
P
L
I
K
A
E
G
L
S
V
I
T
A
V
K
K
A
H
P
D
K
I
V
F
A
D
M
K
T
M
D
A
G
E
L
E
A
D
I
A
F
K
A
G
A
D
L
V
T
V
L
G
S
A
D
D
S
T
I
A
G
A
V
K
A
A
Q
A
H
N
K
G
V
V
V
D
L
I
G
I
E
D
K
A
-
T
R
A
Q
E
V
R
A
L
G
A
K
F
V
E
M
H
A
G
L
D
E
Q
A
------
K
-
P
-
G
-
F
--
D
L
N
G
L
L
A
-
A
G
-
E
-
K
A
R
V
PF
S
V
A
G
G
V
K
V
A
T
I
P
A
V
Q
K
A
G
A
E
V
A
V
A
G
G
A
I
---------------------
103
Fugue
68.54
31%
-119
- C1 -
1KV8
2
ULAD_ECOLI
A:
[3-215]
L
P
M
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
-
W
-
E
Q
A
Q
Q
W
R
D
A
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
W
G
-
E
A
-
D
I
T
A
I
K
R
-
L
S
-
D
M
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
L
W
2
PsiBlast_PDB
68.30
40%
-118
- C1 -
3AJX
3
HPS_MYCGS
A:
[1-189]
-
M
K
L
Q
V
A
I
D
L
L
S
T
E
A
A
L
E
L
A
G
K
V
A
E
Y
V
D
I
I
E
L
G
T
P
L
I
K
A
E
G
L
S
V
I
T
A
V
K
K
A
H
P
D
K
I
V
F
A
D
M
K
T
M
D
A
G
E
L
E
A
D
I
A
F
K
A
G
A
D
L
V
T
V
L
G
S
A
D
D
S
T
I
A
G
A
V
K
A
A
Q
A
H
N
K
G
V
V
V
D
L
I
G
I
E
D
K
A
-
T
R
A
Q
E
V
R
A
L
G
A
K
F
V
E
M
H
A
G
L
D
E
Q
A
------
K
-
P
-
G
-
F
--
D
L
N
G
L
L
A
-
A
G
-
E
-
K
A
R
V
P
F
S
V
A
G
G
V
K
V
A
T
I
P
A
V
Q
K
A
G
A
E
V
A
V
A
G
G
A
I
---------------------
130
HHSearch
68.00
27%
-122
- C1 -
3JR2
9
?
A:
[7-215]
-
P
M
I
Q
I
A
L
D
Q
T
N
L
T
D
A
V
A
V
A
S
N
V
A
S
Y
V
D
V
I
E
V
G
T
I
L
A
F
A
E
G
M
K
A
V
S
T
L
R
H
N
H
P
N
H
I
L
V
C
D
M
K
T
T
D
G
G
A
I
L
S
R
M
A
F
E
A
G
A
D
W
I
T
V
S
A
A
A
H
I
A
T
I
A
A
C
K
K
V
A
D
E
L
N
G
E
I
Q
I
E
I
Y
G
N
W
T
M
--
Q
D
A
K
A
W
V
D
L
G
I
T
Q
A
I
Y
H
R
S
R
D
A
E
L
A
G
----
I
G
W
-
T
-
T
D
-
D
L
D
K
M
R
Q
-
L
S
A
L
-
G
I
E
L
--
S
I
T
G
G
I
V
P
E
D
I
Y
L
F
E
G
I
K
T
K
T
F
I
A
G
R
A
L
A
G
A
E
G
Q
-
Q
T
A
A
A
L
R
E
Q
I
D
R
--
14
PsiBlast_PDB
67.30
32%
-115
- C1 -
1SO4
3
ULAD_ECOLI
A:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
A
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
114
HHSearch
66.81
30%
-125
- C1 -
1Q6O
3
ULAD_ECOLI
A:
[4-214]
-
P
M
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
-
E
L
T
G
Y
W
T
W
-
E
Q
A
Q
Q
W
R
D
A
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
VAWG
E
-
A
-
D
-
I
T
-
A
I
K
R
L
S
D
----
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
L
-
36
PsiBlast_CBE
65.80
32%
-115
- C1 -
1SO4
3
ULAD_ECOLI
B:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
A
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
4
PsiBlast_PDB
64.83
33%
-116
- C1 -
1XBX
3
ULAD_ECOLI
A:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
D
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
V
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
A
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
3
PsiBlast_PDB
64.68
33%
-112
- C1 -
1XBY
3
ULAD_ECOLI
A:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
D
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
A
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
9
PsiBlast_PDB
64.00
32%
-111
- C1 -
1Q6O
3
ULAD_ECOLI
A:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
6
PsiBlast_PDB
63.59
32%
-111
- C1 -
1KV8
2
ULAD_ECOLI
A:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
10
PsiBlast_PDB
63.45
32%
-115
- C1 -
1Q6Q
3
ULAD_ECOLI
A:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
-----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
7
PsiBlast_PDB
63.33
32%
-113
- C1 -
1KW1
3
ULAD_ECOLI
A:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
16
PsiBlast_PDB
63.31
32%
-112
- C1 -
1SO6
3
ULAD_ECOLI
A:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
Q
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
A
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
11
PsiBlast_PDB
63.28
32%
-111
- C1 -
1Q6R
3
ULAD_ECOLI
A:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
12
PsiBlast_PDB
63.27
32%
-111
- C1 -
1XBV
3
ULAD_ECOLI
A:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
31
PsiBlast_CBE
63.19
32%
-111
- C1 -
1Q6O
3
ULAD_ECOLI
B:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
13
PsiBlast_PDB
63.17
32%
-112
- C1 -
1SO5
3
ULAD_ECOLI
A:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
Q
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
38
PsiBlast_CBE
62.89
32%
-116
- C1 -
1SO6
3
ULAD_ECOLI
B:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
Q
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
A
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
8
PsiBlast_PDB
62.74
32%
-109
- C1 -
1Q6L
3
ULAD_ECOLI
A:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
29
PsiBlast_CBE
62.54
32%
-109
- C1 -
1Q6R
3
ULAD_ECOLI
B:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
15
PsiBlast_PDB
62.45
32%
-112
- C1 -
1SO3
3
ULAD_ECOLI
A:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
A
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
27
PsiBlast_CBE
62.23
33%
-114
- C1 -
1XBX
3
ULAD_ECOLI
B:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
D
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
V
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
A
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
25
PsiBlast_CBE
62.22
33%
-111
* C1 *
1XBY
3
ULAD_ECOLI
B:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
D
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
A
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
30
PsiBlast_CBE
61.91
32%
-111
- C1 -
1Q6Q
3
ULAD_ECOLI
B:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
37
PsiBlast_CBE
61.78
32%
-115
- C1 -
1SO3
3
ULAD_ECOLI
B:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
A
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
35
PsiBlast_CBE
61.65
32%
-109
- C1 -
1SO5
3
ULAD_ECOLI
B:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
Q
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
32
PsiBlast_CBE
61.37
32%
-111
- C1 -
1Q6L
3
ULAD_ECOLI
B:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
26
PsiBlast_CBE
61.27
33%
-112
- C1 -
1XBZ
2
ULAD_ECOLI
B:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
D
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
V
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
A
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
28
PsiBlast_CBE
61.11
32%
-110
- C1 -
1XBV
3
ULAD_ECOLI
B:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
5
PsiBlast_PDB
60.88
33%
-111
- C1 -
1XBZ
4
ULAD_ECOLI
A:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
D
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
V
D
A
Q
-------
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
A
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--
33
PsiBlast_CBE
60.81
32%
-110
- C1 -
1KW1
3
ULAD_ECOLI
B:
[6-213]
---
L
Q
V
A
L
D
N
Q
T
M
D
S
A
Y
E
T
T
R
L
I
A
E
E
V
D
I
I
E
V
G
T
I
L
C
V
G
E
G
V
R
A
V
R
D
L
K
A
L
Y
P
H
K
I
V
L
A
D
A
K
I
A
D
A
G
K
I
L
S
R
M
C
F
E
A
N
A
D
W
V
T
V
I
C
C
A
D
I
N
T
A
K
G
A
L
D
V
A
K
E
F
N
G
D
V
Q
I
E
L
T
G
Y
W
T
W
E
-
Q
A
Q
Q
W
R
D
A
-
G
I
G
Q
V
V
Y
H
R
S
R
D
A
Q
A
A
G
----
V
-
A
-
W
-
G
E
A
D
I
T
A
I
K
R
L
S
D
-
M
-
G
F
K
V
--
T
V
T
G
G
L
A
L
E
D
L
P
L
F
K
G
I
P
I
H
V
F
I
A
G
R
S
I
R
D
A
A
S
P
V
E
A
A
R
Q
F
K
R
S
I
A
E
--