@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu11510: (2016-06-18 )
MEHDYLISLLVIVGIDLILGGDNAVVIAMASRHLPDKQRQQAIILGTFIAVAMRIGLTSAAVYLLNIPFLQCAGGIFLLYLGYQLLIEKKDTKHIKSSTSLWRAIRTIVLADLFMSLDNVIAVAGASHGEFSLVVIGLCVSVPVIIWGSKLIHIALEKIPLLIYAGSGLLAYTGGEMIVRDKKLSLFMAQHGTVETLLPILTVAFVILASIYYQQVEK
Atome Classification :
(20 SA)
-----------------------------.........10....--------------....20........30........40-.-------.......----50........----60........-70....-----------------------------....80-..---------......-.90.-.......100.......-----------110----.....---..120....-------------------...130..------------------------------------.-....-140.....---..150.......160------------------.........170-.-......180.......190......-----.---200.......210......---------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------ME
H
D
Y
L
I
S
L
L
V
I
VGI--------------
D
L
I
LGGD
N
A
V
V
I
A
MASRHLP
D
K
Q
R
Q
Q
-
A
-------
I
I
L
G
T
F
I
----
A
V
A
M
R
IG
L
T
S
----
A
A
V
Y
L
L
NI
P
F
-
L
QCA
G
G
-----------------------------
I
F
L
L
Y
--
L
G
---------
Y
Q
L
L
IE-KKD
T
-
K
H
I
K
S
S
T
S
L
W
R
A
I
R
T
I
V
-----------
L
A
D
----
L
F
M
S
L
---
D
N
V
I
A
V
AGA-------------------SHG
E
F
S
L
V
------------------------------------
V
-
I
G
L
C
-VSV
P
V
I
I
W---G
S
K
L
I
H
I
A
L
E
KI
P
--------------------
L
L
I
Y
AGS
G
L
L
A
Y-T-GG
E
M
I
V
RDK
K
L
S
L
F
MAQHG
T
V
E
T
L
L
-----
P
---
I
L
T
V
A
F
V
I
L
A
S
I
Y
Y
Q
Q
VEK---------------
26
Fugue
61.55
22%
-174
- C4 -
4R6Y
2
PHNS_SALTY
A:
[1-317]
---------------------------------
S
M
E
S
V
V
T
V
Y
S
I
--------------
D
G
L
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D
G
D
N
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Y
Q
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Q
F
D
A
F
T
K
A
T
G
I
T
V
-
R
-------
Y
V
E
G
G
G
G
----
V
V
V
E
R
L
A
K
E
R
TNPQ
A
D
V
L
V
T
A
P
P
F
-
I
Q
R
A
A
A
E
KLL
A
N
F
N
T
DTASAIPDANNL
Y
S
P
L
V
K
N
Y
L
S
F
I
Y
--
N
S
KLLKTAPAS
W
Q
D
L
L
D
-
G
K
F
K
-
N
K
L
Q
Y
S
T
P
G
Q
A
A
D
G
T
A
V
-----------
M
L
Q
----
A
F
H
S
F
GS
K
D
A
G
F
A
Y
L
G
K
L
Q
A
N
NVGPSAST
G
K
L
T
A
L
V
N
K
G
E
I
Y
V
A
N
G
D
L
Q
M
N
L
A
Q
MERNPN
V
K
I
F
W
P
A
N
DKG
E
R
S
A
L
A
I
P
Y
V
-
I
G
L
V
-
Q
G
A
P
Q
S
E
N
---
G
K
K
L
I
N
F
L
L
S
K
E
A
--------------------
Q
T
R
V
S
E
L
S
W
G
M
P
-
V
-
R
S
D
V
T
P
S
D
E
H
Y
K
A
A
T
A
A
L
E
G
V
Q
S
W
Q
-----
P
N
W
D
D
V
A
V
S
L
S
A
D
I
S
R
W
H
K
V
T
E
S
---------------
20
Fugue
59.00
24%
-205
- C6 -
4PE6
1
?
A:
[18-339]
K
P
F
I
A
L
S
N
GFIGN
G
W
R
Q
T
M
I
A
K
F
E
E
A
A
K
Q
A
Q
A
D
G
L
I
G
K
Y
K
V
V
N
A
P
G
NNS
A
T
E
Q
V
A
Q
I
K
S
L
L
L
Q
K
P
D
A
L
L
I
N
P
A
S
P
T
A
L
Q
P
V
I
Q
Q
-
A
C
D
A
G
V
K
V
V
V
F
D
S
A
I
DAPC
A
Y
I
L
Q
N
S
F
V
D
----
W
A
T
Y
A
A
K
-
P
V
-
L
E
S
I
G
G
K
G
N
--------------------------
V
I
V
V
R
G
V
V
G
---------
S
Q
P
E
A
E
M
Y
E
T
T
-
K
K
I
L
A
E
Y
P
Q
V
K
T
V
A
T
V
T
GMCD
G
A
T
A
Q
K
A
V
L
G
----
V
L
P
S
V
---
S
T
V
D
A
V
I
G
C
-------------------
G
D
G
Y
G
V
A
Q
------------------------------------
A
-
F
A
T
A
G
K
P
I
P
A
V
T
F
E
TN
G
R
A
L
S
Y
W
K
D
N
K
I
D
NG
S
V
A
V
M
S
D
PA
Q
S
V
A
A
L
W
A
A
L
D
L
L
E
G
R
D
L
P
K
Q
M
T
-
F
P
I
V
L
I
E
E
K
D
R
D
T
W
A
S
V
------
L
K
-----
P
---
D
E
Y
A
A
W
P
W
T
R
E
L
F
R
Q
Q
V
E
A
I
K
T
GGEPVQPPIPST
29
Fugue
45.63
20%
-136
- C6 -
4UN1
1
?
B:
[21-179]
-----------------------------
M
S
H
Q
F
----------------------------
S
P
E
E
Q
A
V
L
R
I
V
Q
A
N
L
P
D
S
---------------
L
T
P
Y
A
----
D
L
A
E
Q
A
G
M
T
E
----
A
Q
V
L
E
L
-
L
G
R
-
L
K
A
S
G
A
-----------------------------
I
------
R
R
---------
F
G
A
S
I
K
-
H
Q
K
T
-
G
W
T
H
N
A
M
V
A
W
K
V
T
------------------------
P
D
Q
---
V
D
D
C
G
R
K
A
A
-------------------
E
H
S
H
I
S
H
V
------------------------------------
Y
-
Y
R
--------------
P
S
S
A
P
D
W
P
Y
E
-
M
Y
--------------------
T
M
I
H
G
R
S
----
E
-
A
-
E
C
L
G
V
V
E
D
V
K
R
T
T
S
L
K
E
H
A
I
L
R
S
L
K
-----
E
---
L
K
K
T
S
M
T
-----
Y
F
T
-------------------
24
Fugue
42.05
12%
-144
* C6 *
2W69
6
PA_I75A3
A:
[7-203]
-----------------------------
A
M
E
D
F
V
R
Q
C
F
--------------------------
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
L
-
K
-------
I
E
T
N
K
F
A
----
A
I
C
T
H
L
E
V
C
F
----
M
Y
S
---
D
F
H
F
-
I
N
E
Q
G
E
-----------------------------
S
I
V
V
E
--
L
D
---------
D
P
N
A
L
K
-
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
-----------
N
T
T
----
G
A
E
K
P
---
K
F
L
P
D
L
Y
D
---------------------
Y
K
E
N
R
F
I
------------------------------------
E
-
I
G
V
T
-
R
R
E
V
H
I
Y
Y
---
L
E
K
A
N
K
I
K
S
T
H
I
H
--------------------
I
F
S
F
T
G
E
E
M
A
---
T
-
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
-----
A
---
N
R
G
L
W
D
S
F
R
Q
S
------
E
R
---------------
22
Fugue
36.89
15%
-168
* C8 *
4GS4
1
ATAT_HUMAN
A:
[7-199]
-------------------------------
F
P
F
D
V
D
A
L
F
-----------------------
P
E
R
I
T
V
L
D
Q
H
L
R
P
P
V
D
L
Q
Q
Q
I
M
T
-------
I
I
D
E
L
G
K
----
A
S
A
K
A
Q
N
L
S
A
----
P
---
I
T
S
A
S
R
M
Q
S
N
R
H
V
-----------------------------
V
Y
I
L
K
--
D
S
AI-------
I
G
F
I
K
V
-
G
Y
K
K
-
L
F
V
L
D
D
R
E
A
H
N
E
V
E
P
L
C
-----------
I
L
D
----
F
Y
I
-------
H
E
S
V
Q
R
H
-------------------
G
H
G
R
E
L
F
Q
------------------------------------
Y
M
L
Q
K
---------
E
---
R
V
E
P
H
Q
L
A
I
D
R
P
-------------------------------------------
S
Q
K
L
L
K
F
L
N
K
H
Y
N
L
E
T
T
V
-----
P
---
Q
V
N
-
N
F
V
I
F
E
G
-
F
F
A
H
Q
H
R
---------------
15
HHSearch
29.34
25%
-285
- C7 -
2D7C
-
RFIP3_HUMAN
C:
[27-38]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
V
A
I
M
E
T
N
P
--------------------
S
I
---------------------------------------------------------------------------------
25
Fugue
29.33
12%
-144
- C3 -
1KKE
-
SIGM1_REOVD
A:
[250-455]
------------------------------------------
E
Q
--------------
S
Y
V
A
S
A
V
T
P
L
R
L
N
S
S
T
K
V
L
D
M
L
I
D
S
S
-
T
-------
L
E
I
N
S
S
G
----
Q
L
T
V
R
S
T
S
P
N
---------
L
R
Y
P
I
-
A
D
V
S
G
G
-----------------------------
I
G
M
S
P
--
N
Y
---------
R
F
R
Q
S
M
-
W
I
G
I
-
V
S
Y
S
G
S
G
L
N
W
R
V
Q
V
N
S
D
-----------
I
F
I
V
DD
Y
I
H
I
C
L
---
P
A
F
D
G
F
S
I
A
-------------------
D
G
G
D
L
S
L
N
------------------------------------
F
-
V
T
G
L
-
L
P
P
----
L
---
L
T
G
D
T
E
P
A
F
H
N
D
V
--------------------
V
T
Y
G
A
Q
T
V
A
I
G
L
-
S
S
G
G
A
P
Q
Y
M
S
K
N
L
W
V
E
Q
W
Q
D
G
V
L
R
L
R
V
E
G
GGS
I
---
T
H
S
N
S
K
W
P
A
M
T
V
S
Y
P
R
S
F
T
---------------
13
HHSearch
29.15
30%
-790
- C1 -
1O8R
-
A:
[6-15]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
N
----
F
S
F
S
L
---
E
S
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
27.81
24%
-83
- C8 -
2HIN
2
?
A:
[1-66]
------------------------------------------------------------------------------
M
K
P
E
E
L
-
V
-------
R
H
F
G
D
V
E
----
K
A
A
V
G
V
G
V
T
P
----
G
A
V
Y
Q
W
L
Q
A
------
G
E
-----------------------------
I
---
P
--
P
L
---------
R
Q
S
D
I
E
-
V
R
T
A
-
Y
K
L
K
S
D
F
T
S
Q
R
M
G
K
E
G
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
25.12
25%
-104
- C7 -
4XP5
2
DAT_DROME
A:
[348-398]
-------------------------------------
M
L
A
T
L
G
L
--------------
D
S
S
F
G
G
S
E
A
I
I
T
A
L
-
S
D
E
F
P
K
I
K
R
N
R
-
E
-------
L
F
V
A
G
L
F
----
S
L
Y
F
V
V
G
L
A
S
----
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
25.08
25%
-133
- C7 -
4M48
2
DAT_DROME
A:
[351-401]
-------------------------------------
M
L
A
T
L
G
L
--------------
D
S
S
F
G
G
S
E
A
I
I
T
A
L
-
S
D
E
F
P
K
I
K
R
N
R
-
E
-------
L
F
V
A
G
L
F
----
S
L
Y
F
V
V
G
L
A
S
----
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
24.88
25%
-128
- C7 -
4XNU
2
DAT_DROME
A:
[346-396]
-------------------------------------
M
L
A
T
L
G
L
--------------
D
S
S
F
G
G
S
E
A
I
I
T
A
L
-
S
D
E
F
P
K
I
K
R
N
R
-
E
-------
L
F
V
A
G
L
F
----
S
L
Y
F
V
V
G
L
A
S
----
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
24.85
25%
-130
- C7 -
4XP6
2
DAT_DROME
A:
[348-398]
-------------------------------------
M
L
A
T
L
G
L
--------------
D
S
S
F
G
G
S
E
A
I
I
T
A
L
-
S
D
E
F
P
K
I
K
R
N
R
-
E
-------
L
F
V
A
G
L
F
----
S
L
Y
F
V
V
G
L
A
S
----
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
24.29
33%
101
- C7 -
2KE4
-
A:
[336-347]
--------------------------------------------------------------------------
S
H
L
P
P
E
Q
Q
R
K
-
R
-------
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
24.26
25%
-120
- C7 -
4XNX
2
DAT_DROME
A:
[348-398]
-------------------------------------
M
L
A
T
L
G
L
--------------
D
S
S
F
G
G
S
E
A
I
I
T
A
L
-
S
D
E
F
P
K
I
K
R
N
R
-
E
-------
L
F
V
A
G
L
F
----
S
L
Y
F
V
V
G
L
A
S
----
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
24.22
25%
-117
- C7 -
4XPA
2
DAT_DROME
A:
[353-403]
-------------------------------------
M
L
A
T
L
G
L
--------------
D
S
S
F
G
G
S
E
A
I
I
T
A
L
-
S
D
E
F
P
K
I
K
R
N
R
-
E
-------
L
F
V
A
G
L
F
----
S
L
Y
F
V
V
G
L
A
S
----
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
24.20
25%
-122
- C7 -
4XP4
2
DAT_DROME
A:
[353-403]
-------------------------------------
M
L
A
T
L
G
L
--------------
D
S
S
F
G
G
S
E
A
I
I
T
A
L
-
S
D
E
F
P
K
I
K
R
N
R
-
E
-------
L
F
V
A
G
L
F
----
S
L
Y
F
V
V
G
L
A
S
----
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
23.86
25%
-132
- C7 -
4XP1
2
DAT_DROME
A:
[348-398]
-------------------------------------
M
L
A
T
L
G
L
--------------
D
S
S
F
G
G
S
E
A
I
I
T
A
L
-
S
D
E
F
P
K
I
K
R
N
R
-
E
-------
L
F
V
A
G
L
F
----
S
L
Y
F
V
V
G
L
A
S
----
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
23.73
25%
-129
- C7 -
4XP9
2
DAT_DROME
C:
[348-398]
-------------------------------------
M
L
A
T
L
G
L
--------------
D
S
S
F
G
G
S
E
A
I
I
T
A
L
-
S
D
E
F
P
K
I
K
R
N
R
-
E
-------
L
F
V
A
G
L
F
----
S
L
Y
F
V
V
G
L
A
S
----
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
22.49
27%
-606
- C2 -
2K5C
-
?
A:
[23-33]
------------------------------------------
L
I
--------------
E
E
M
L
I
I
E
N
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------