@TOME V2.3
(Nov 2016)

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3D Common Core:

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Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : AKT1_HUMAN: (2013-07-18 )
MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA

Atome Classification :

(100 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......-160.......---170-.---.-.----......180.......190.......200..--..-....210.......220.......230.......240.----.......250.......260.......270.......280.-......290.......300...-..--..310.......320-----..---.....330.......340...-....350.---.----.......360..--.....-370--........380.......390..-..-...400.......410---.......420.......430----........440.......450.......460......---.470.......480
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPH---FPQFSYSASGTA
115 HHSearch 91.5699%-109 - C1 -4EJN AKT1_HUMAN A:[4-438] ---VAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERP-------APLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADG----------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIV-------------V-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIK------K--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYF---------------------------------------------
3 PsiBlast_PDB 82.1199%-104 - C1 -3OCB AKT1_HUMAN A:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDEEFTAQM-------------------RPH---FPQFDYSASS--
10 PsiBlast_PDB 81.6799%-105 - C1 -4GV1 AKT1_HUMAN A:[4-337] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDEEFTAQMITITP-----SMECVDSERRPH---FPQFDYSAS---
6 PsiBlast_PDB 81.6699%-104 - C1 -3QKL AKT1_HUMAN A:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDEEFTAQMIT-----------------RPH---FPQFDYSASS--
11 PsiBlast_PDB 81.1099%-105 - C1 -3CQW AKT1_HUMAN A:[6-340] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDEEFTAQMI----------------ERRPH---FPQFDYSASS--
13 PsiBlast_PDB 80.9399%-102 - C1 -3MVH AKT1_HUMAN A:[7-338] ------------------------------------------------------------------------------------------------------------------------------------------------VTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDEEFTAQ--------------------RPH---FPQFDYSA----
12 PsiBlast_PDB 80.4299%-102 - C1 -3MV5 AKT1_HUMAN A:[6-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDEEFTAQMI------------------RPH---FPQFDYSAS---
4 PsiBlast_PDB 78.9599%-102 - C1 -3OW4 AKT1_HUMAN A:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDEEFTAQMIT-----------------RPH---FPQFDYSASS--
7 PsiBlast_PDB 78.8099%-104 - C1 -3QKM AKT1_HUMAN A:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDEEFTAQMITITP-----SMECVDSERRPH---FPQFDYSASS--
17 PsiBlast_PDB 78.5885%-107 - C1 -3E88 AKT2_HUMAN A:[1-333] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-LQ--NT-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E----RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHERLFELILME--EIRFP-RT---LSPEAKSLLAGLLKKDPKQRLGG-GP-SDAKEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDDEFTAQSITIT--------------QRTH---FPQFDYSAS---
9 PsiBlast_PDB 78.5699%-103 - C1 -4EKL AKT1_HUMAN A:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDEEFTAQMITITP-----SMECVDSERRPH---FPQFDYSASS--
5 PsiBlast_PDB 78.2899%-102 - C1 -3QKK AKT1_HUMAN A:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDEEFTAQMITI--------MECVDSERRPH---FPQFDYSASS--
8 PsiBlast_PDB 78.2499%-101 - C1 -4EKK AKT1_HUMAN A:[5-338] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDEEFTAQMI---------------SERRPH---FPQFDYSAS---
118 HHSearch 77.9985%-106 - C1 -1O6L AKT2_HUMAN A:[1-336] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-LQ--NT-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E----RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHERLFELILME--EIRFP-RT---LSPEAKSLLAGLLKKDPKQRLGG-GP-SDAKEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDDEFTAQSIT-----------------QEM---FEDFDYIAD---
16 PsiBlast_PDB 77.8785%-107 - C1 -3E87 AKT2_HUMAN A:[1-333] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-LQ--NT-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E----RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHERLFELILME--EIRFP-RT---LSPEAKSLLAGLLKKDPKQRLGG-GP-SDAKEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDDEFTAQSITITPP------------QRTH---FPQFDYSAS---
15 PsiBlast_PDB 77.6085%-107 - C1 -1O6K AKT2_HUMAN A:[1-333] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-LQ--NT-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E----RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHERLFELILME--EIRFP-RT---LSPEAKSLLAGLLKKDPKQRLGG-GP-SDAKEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDDEFTAQSIT----------------QRTH---FPQFDYSAS---
18 PsiBlast_PDB 76.6985%-107 - C1 -3E8D AKT2_HUMAN A:[1-333] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-LQ--NT-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E----RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHERLFELILME--EIRFP-RT---LSPEAKSLLAGLLKKDPKQRLGG-GP-SDAKEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDDEFTAQSIT-------------------H---FPQFDYSAS---
19 PsiBlast_PDB 74.9685%-107 - C1 -3D0E AKT2_HUMAN A:[1-333] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-LQ--NT-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E----RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDGAT-MK--TFCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHERLFELILME--EIRFP-RT---LSPEAKSLLAGLLKKDPKQRLGG-GP-SDAKEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDDEFTAQSITITPPD-----------QRTH---FPQFDYSAS---
129 HHSearch 62.2739% -89 - C1 -4AW2 MRCKA_RAT A:[70-408] -----------------------------------------------------------------------------------------------------------------------------------------------RLHREDFEILKVIGRG-AFGEVAVVKL---K---N---A-D----KVFAMKILNKWEMLKRAETACFREERDV-LV--NG-DSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFE----DRLPEEMARFYLAEMVIAIDSVHQ-LHYVHRDIKPDNILMD-MNGHIRLADFGSCLKLMEDGTVQSS--VAVGTPDYISPEILQAMEGGKG---RYGPECDWWSLGVCMYEMLYG-ETPFY--A---E----SLVETYGKIMNHKERFQFP-TQVTDVSENAKDLIRRLICSRE-HRLG---Q-NGIEDFKKHPFFSGID---WDNI--RNCEAPYIPEVSS-----PTDTSNFDVD---------------------SGHHLP---FVGFTYTSSCV-
132 HHSearch 59.3942% -87 - C1 -1RDQ KAPCA_MOUSE E:[34-341] --------------------------------------------------------------------------------------------------------------------------------------------SQNTAQLDQFDRIKTLGTG-SFGRVMLVKH---K---E---S-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQ--AV-NFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRR-I----GRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLID-QQGYIQVTDFGFAKRV---KGR-TW--TLCGTPEALAPEIIL-----SK---GYNKAVDWWALGVLIYEMAAG-YPPFF--A---D----QPIQIYEKIVSG--KVRFP-SH---FSSDLKDLLRNLLQVDLTKRFGN-LK-NGVNDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFD-DYEEEEIRVSINE------------------------------
120 HHSearch 58.6446% -91 - C1 -4DC2 KPCI_MOUSE A:[49-387] ------------------------------------------------------------------------------------------------------------------------------------------------LGLQDFDLLRVIGRG-SYAKVLLVRL---K---K---T-D----RIYAMRVVKKELVN----IDWVQTEKHV-FE--QASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQR-Q----RKLPEEHARFYSAEISLALNYLHE-RGIIYRDLKLDNVLLD-SEGHIKLTDYGMCKEGLRPGDT-TS--TFCGTPNYIAPEILR-----GE---DYGFSVDWWALGVLMFEMMAG-RSPFD--IVGSN----TEDYLFQVILEK--QIRIP-RS---LSVKAASVLKSFLNKDPKERLGC-HPQTGFADIQGHPFFRNVD---WDMMEQKQVVPPFKPNISG-----EFGLDNFDSQFTNEPVQLTPDDDDI----VRKIDQSE---FEGFEYINP---
124 HHSearch 58.4346%-102 - C1 -1XJD A:[16-335] --------------------------------------------------------------------------------------------------------------------------------------------------IEDFILHKMLGKG-SFGKVFLAEF---K---K---T-N----QFFAIKALKKDVVLMDDDVECTMVEKRV-LS--LAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQS-C----HKFDLSRATFYAAEIILGLQFLHS-KGIVYRDLKLDNILLD-KDGHIKIADFGMCKENMLGDAK-TN--TFCGTPDYIAPEILL-----GQ---KYNHSVDWWSFGVLLYEMLIG-QSPFH--G---Q----DEEELFHSIRMD--NPFYP-RW---LEKEAKDLLVKLFVREPEKRLGV-R-----GDIRQHPLFREIN---WEELERKEIDP-----------------------------------------------QNM---FRNFSF------
121 HHSearch 56.9349%-107 - C1 -2R5T SGK1_HUMAN A:[31-320] --------------------------------------------------------------------------------------------------------------------------------------------SNPHAKPSDFHFLKVIGKG-SFGKVLLARH---K---A---E-E----VFYAVKVLQKKAIL-------------VLLK--NV-KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR-E----RCFLEPRARFYAAEIASALGYLHS-LNIVYRDLKPENILLD-SQGHIVLTDFGLCKENIEHNST-TS--TFCGTPEYLAPEVLH-----KQ---PYDRTVDWWCLGAVLYEMLYG-LPPFY--S---R----NTAEMYDNILNK--PLQLK-PN---ITNSARHLLEGLLQKDRTKRLGA-K--DDFMEIKSHVFFSLIN---WDDLINKKITPPFNPNVSG---------------------------------------------------------
67 PsiBlast_CBE 55.8444% -89 - C1 -2OJF KAPCA_BOVIN E:[41-330] --------------------------------------------------------------------------------------------------------------------------------------------------LDQFERIKTLGTG-SFGRVMLVKH---M---E---T-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQ--AV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-I----GRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLID-QQGYIQVTDFGFAKR--VKGRT-W---TLCGTPEYLAPEIIL-----SK---GYNKAVDWWALGVLIYEMAAG-YPPFF--A---D----QPIQIYEKIVSG--KVRFP-SH---FSSDLKDLLRNLLQVDLTKRFGN-LK-NGVNDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFDD-------------------------------------------
71 PsiBlast_CBE 55.2944% -89 - C1 -2F7E KAPCA_BOVIN E:[41-330] --------------------------------------------------------------------------------------------------------------------------------------------------LDQFERIKTLGTG-SFGRVMLVKH---M---E---T-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQ--AV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-I----GRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLID-QQGYIQVTDFGFAKR--VKGRT-W---TLCGTPEYLAPEIIL-----SK---GYNKAVDWWALGVLIYEMAAG-YPPFF--A---D----QPIQIYEKIVSG--KVRFP-SH---FSSDLKDLLRNLLQVDLTKRFGN-LK-NGVNDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFDD-------------------------------------------
66 PsiBlast_CBE 54.4644% -91 - C1 -2UZT KAPCA_BOVIN A:[26-315] --------------------------------------------------------------------------------------------------------------------------------------------------LDQFERIKTLGTG-SFGRVMLVKH---M---E---T-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQ--AV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-I----GRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLID-QQGYIQVTDFGFAKR--VKGRT-W---TLCGTPEYLAPEIIL-----SK---GYNKAVDWWALGVLIYEMAAG-YPPFF--A---D----QPIQIYEKIVSG--KVRFP-SH---FSSDLKDLLRNLLQVDLTKRFGN-LK-DGVNDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFDD-------------------------------------------
68 PsiBlast_CBE 54.4244% -89 - C1 -2OH0 KAPCA_BOVIN E:[41-330] --------------------------------------------------------------------------------------------------------------------------------------------------LDQFERIKTLGTG-SFGRVMLVKH---M---E---T-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQ--AV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-I----GRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLID-QQGYIQVTDFGFAKR--VKGRT-W---TLCGTPEYLAPEIIL-----SK---GYNKAVDWWALGVLIYEMAAG-YPPFF--A---D----QPIQIYEKIVSG--KVRFP-SH---FSSDLKDLLRNLLQVDLTKRFGN-LK-NGVNDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFDD-------------------------------------------
70 PsiBlast_CBE 53.9244% -86 - C1 -2F7X KAPCA_BOVIN E:[41-330] --------------------------------------------------------------------------------------------------------------------------------------------------LDQFERIKTLGTG-SFGRVMLVKH---M---E---T-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQ--AV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-I----GRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLID-QQGYIQVTDFGFAKR--VKGRT-W---TLCGTPEYLAPEIIL-----SK---GYNKAVDWWALGVLIYEMAAG-YPPFF--A---D----QPIQIYEKIVSG--KVRFP-SH---FSSDLKDLLRNLLQVDLTKRFGN-LK-NGVNDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFDD-------------------------------------------
69 PsiBlast_CBE 53.2344% -95 - C1 -2F7Z KAPCA_BOVIN E:[41-330] --------------------------------------------------------------------------------------------------------------------------------------------------LDQFERIKTLGTG-SFGRVMLVKH---M---E---T-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQ--AV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-I----GRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLID-QQGYIQVTDFGFAKR--VKGRT-W---TLCGTPEYLAPEIIL-----SK---GYNKAVDWWALGVLIYEMAAG-YPPFF--A---D----QPIQIYEKIVSG--KVRFP-SH---FSSDLKDLLRNLLQVDLTKRFGN-LK-NGVNDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFDD-------------------------------------------
40 PsiBlast_CBE 52.9844%-101 - C1 -2Z7S KS6A1_HUMAN A:[25-308] ------------------------------------------------------------------------------------------------------------------------------------------ADPSH------FELLKVLGQG-SFGKVFLVRK---V---TRPDS-G----HLYAMKVLK------------------I-LA--DV-NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK-E----VMFTEEDVKFYLAELALGLDHLHS-LGIIYRDLKPENILLD-EEGHIKLTDFGLSKE---------------GTVEYMAPEVVN-----RQ---GHSHSADWWSYGVLMFEMLTG-SLPFQ--G---K----DRKETMTLILKA--KLGMP-QF---LSTEAQSLLRALFKRNPANRLGS-GP-DGAEEIKRHVFYSTID---WNKLYRREIKPPFKP-------------------------------------------------------------
131 HHSearch 52.9634% -88 - C1 -3C4Z RK_BOVIN A:[180-510] ----------------------------------------------------------------------------------------------------------------------------------------------QPMGEDWFLDFRVLGRG-GFGEVFACQM---K---A---T-G----KLYACKKLNKKRLKKRKGYQGAMVEKKI-LA--KV-HSRFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYN-VDEDNPGFQEPRAIFYTAQIVSGLEHLHQ-RNIIYRDLKPENVLLD-DDGNVRISDLGLAVELKAGQTK-TK--GYAGTPGFMAPELLL-----GE---EYDFSVDYFALGVTLYEMIAA-RGPFR--A---RGEKVENKELKQRVLEQ--AVTYP-DK---FSPASKDFCEALLQKDPEKRLGF-RD-GSCDGLRTHPLFRDIS---WRQLEAGMLTPPFVPDSRTVYAKN----GAFS------GVAF------------EKADTEF---FQEFASGT----
63 PsiBlast_CBE 52.6744% -88 - C1 -2UZW KAPCA_BOVIN E:[26-315] --------------------------------------------------------------------------------------------------------------------------------------------------LDQFERIKTLGTG-SFGRVMLVKH---M---E---T-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQ--AV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-I----GRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLID-QQGYIQVTDFGFAKR--VKGRT-W---TLCGTPEYLAPEIIL-----SK---GYNKAVDWWALGVLIYEMAAG-YPPFF--A---D----QPIQIYEKIVSG--KVRFP-SH---FSSDLKDLLRNLLQVDLTKRFGN-LK-DGVNDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFDD-------------------------------------------
31 PsiBlast_CBE 52.3449%-105 - C1 -3HDM SGK1_HUMAN A:[38-320] ---------------------------------------------------------------------------------------------------------------------------------------------------SDFHFLKVIGKG-SFGKVLLARH---K---A---E-E----VFYAVKVLQKKAIL------------VL-LK--NV-KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR-E----RCFLEPRARFYAAEIASALGYLHS-LNIVYRDLKPENILLD-SQGHIVLTDFGLCKENIEHNST-TS--TFCGTPEYLAPEVLH-----KQ---PYDRTVDWWCLGAVLYEMLYG-LPPFY--S---R----NTAEMYDNILNK--PLQLK-PN---ITNSARHLLEGLLQKDRTKRL-G-AK-DDFMEIKSHVFFSLIN---WDDLINKKITPPFNPNVSG---------------------------------------------------------
65 PsiBlast_CBE 52.2044% -87 - C1 -2UZU KAPCA_BOVIN E:[26-315] --------------------------------------------------------------------------------------------------------------------------------------------------LDQFERIKTLGTG-SFGRVMLVKH---M---E---T-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQ--AV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-I----GRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLID-QQGYIQVTDFGFAKR--VKGRT-W---TLCGTPEYLAPEIIL-----SK---GYNKAVDWWALGVLIYEMAAG-YPPFF--A---D----QPIQIYEKIVSG--KVRFP-SH---FSSDLKDLLRNLLQVDLTKRFGN-LK-DGVNDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFDD-------------------------------------------
122 HHSearch 52.0246% -89 - C1 -3TXO KPCL_HUMAN A:[23-349] ---------------------------------------------------------------------------------------------------------------------------------------------------DNFEFIRVLGKG-SFGKVMLARV---K---E---T-G----DLYAVKVLKKDVILQDDDVECTMTEKRI-LS--LARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQK-S----RRFDEARARFYAAEIISALMFLHD-KGIIYRDLKLDNVLLD-HEGHCKLADFGMCKEGIC------------GTPDYIAPEILQ-----EM---LYGPAVDWWAMGVLLYEMLCG-HAPFE--A---E----NEDDLFEAILND--EVVYP-TW---LHEDATGILKSFMTKNPTMRLGSLTQ-GGEHAILRHPFFKEID---WAQLNHRQIEPPFRPRIKS-----REDVSNFDPDFIKEEPVLTPIDEGHLP----MINQDE---FRNFEYVSP---
135 HHSearch 51.7547% -99 * C1 *3A62 KS6B1_HUMAN A:[13-300] -----------------------------------------------------------------------------------------------------------------------------------------------KIRPECFELLRVLGKG-GYGKVFQVRK---VTGAN---T-G----KIFAMKVLK-------------KAERNI-LE--EV-KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER-E----GIFMEDTACFYLAEISMALGHLHQ-KGIIYRDLKPENIMLN-HQGHVKLTDFGLC-----------H--TFCGTIEYMAPEILM-----RS---GHNRAVDWWSLGALMYDMLTG-APPFT--G---E----NRKKTIDKILKC--KLNLP-PY---LTQEARDLLKKLLKRNAASRLGA-GP-GDAGEVQAHPFFRHIN---WEELLARKVEPPFKPL------------------------------------------------------------
41 PsiBlast_CBE 51.6344% -98 - C1 -2Z7R KS6A1_HUMAN A:[25-308] ------------------------------------------------------------------------------------------------------------------------------------------ADPSH------FELLKVLGQG-SFGKVFLVRK---V---TRPDS-G----HLYAMKVLKKATLKV------------I-LA--DV-NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK-E----VMFTEEDVKFYLAELALGLDHLHS-LGIIYRDLKPENILLD-EEGHIKLTDFGLSKE---------------GTVEYMAPEVVN-----RQ---GHSHSADWWSYGVLMFEMLTG-SLPFQ--G---K----DRKETMTLILKA--KLGMP-QF---LSTEAQSLLRALFKRNPANRLGS-GP-DGAEEIKRHVFYSTID---WNKLYRREIKPPFKP-------------------------------------------------------------
42 PsiBlast_CBE 51.5244%-100 - C1 -2Z7Q KS6A1_HUMAN A:[25-308] ------------------------------------------------------------------------------------------------------------------------------------------ADPSH------FELLKVLGQG-SFGKVFLVRK---V---TRPDS-G----HLYAMKVL-------------------I-LA--DV-NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK-E----VMFTEEDVKFYLAELALGLDHLHS-LGIIYRDLKPENILLD-EEGHIKLTDFGLSKE---------------GTVEYMAPEVVN-----RQ---GHSHSADWWSYGVLMFEMLTG-SLPFQ--G---K----DRKETMTLILKA--KLGMP-QF---LSTEAQSLLRALFKRNPANRLGS-GP-DGAEEIKRHVFYSTID---WNKLYRREIKPPFKP-------------------------------------------------------------
30 PsiBlast_CBE 50.6749%-107 - C1 -3HDN SGK1_HUMAN A:[38-316] ---------------------------------------------------------------------------------------------------------------------------------------------------SDFHFLKVIGKG-SFGKVLLARH---K---A---E-E----VFYAVKVLQKKAIL------------VL-LK--NV-KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR-E----RCFLEPRARFYAAEIASALGYLHS-LNIVYRDLKPENILLD-SQGHIVLTDFGLCKENIEHNST-TS--TFCGTPEYLAPEVLH-----KQ---PYDRTVDWWCLGAVLYEMLYG-LPPFY--S---R----NTAEMYDNILNK--PLQLK-PN---ITNSARHLLEGLLQKDRTKRL-G-AK-DDFMEIKSHVFFSLIN---WDDLINKKITPPFNP-------------------------------------------------------------
64 PsiBlast_CBE 50.5944% -86 - C1 -2UZV KAPCA_BOVIN A:[26-315] --------------------------------------------------------------------------------------------------------------------------------------------------LDQFERIKTLGTG-SFGRVMLVKH---M---E---T-G----NHYAMKILDKQKVVKLKQIEHTLNEKRI-LQ--AV-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR-I----GRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLID-QQGYIQVTDFGFAKR--VKGRT-W---TLCGTPEYLAPEIIL-----SK---GYNKAVDWWALGVLIYEMAAG-YPPFF--A---D----QPIQIYEKIVSG--KVRFP-SH---FSSDLKDLLRNLLQVDLTKRFGN-LK-DGVNDIKNHKWFATTD---WIAIYQRKVEAPFIPKFKG-----PGDTSNFDD-------------------------------------------
22 PsiBlast_CBE 49.7599% -59 - C1 -3OW4 AKT1_HUMAN B:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGAT-MK---FCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDEEFTAQMIT-----------------RPH---FPQFDYSASS--
85 PsiBlast_CBE 49.5845%-102 - C1 -4GUE KS6A3_MOUSE A:[25-305] ---------------------------------------------------------------------------------------------------------------------------------------------------SQFELLKVLGQG-SFGKVFLVK----K---I---S-GSDARQLYAMKVLKKATLKVRDRV----------LV--EV-NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK-E----VMFTEEDVKFYLAELALALDHLHS-LGIIYRDLKPENILLD-EEGHIKLTDFGLSKE-----KK-AY--SFCGTVEYMAPEVVN-----RR---GHTQSADWWSFGVLMFEMLTG-TLPFQ--G---K----DRKETMTMILKA--KLGMP-QF---LSPEAQSLLRMLFKRNPANRLGA-GP-DGVEEIKRHSFFSTID---WNKLYRREIHPPFKP-------------------------------------------------------------
39 PsiBlast_CBE 49.2546% -99 - C1 -3G51 KS6A3_MOUSE A:[24-304] ---------------------------------------------------------------------------------------------------------------------------------------------------SQFELLKVLGQG-SFGKVFLVK----K---I---S-GSDARQLYAMKVLKKATLKVRD----------I-LV--EV-NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK-E----VMFTEEDVKFYLAELALALDHLHS-LGIIYRDLKPENILLD-EEGHIKLTDFGLSKESI--------------TVEYMAPEVVN-----RR---GHTQSADWWSFGVLMFEMLTG-TLPFQ--G---K----DRKETMTMILKA--KLGMP-QF---LSPEAQSLLRMLFKRNPANRLGA-GP-DGVEEIKRHSFFSTID---WNKLYRREIHPPFKP-------------------------------------------------------------
21 PsiBlast_CBE 48.5599% -61 - C1 -4EKK AKT1_HUMAN B:[5-338] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---K---A---T-G----RYYAMKILKKEVIVAKDEVAHTLTENRV-LQ--NS-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E----RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDGHIKITDFGLCKEGIKDGAT-MK---FCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHEKLFELILME--EIRFP-RT---LGPEAKSLLSGLLKKDPKQRLGG-GS-EDAKEIMQHRFFAGIV---WQHVYEKKLSPPFKPQVTS-----ETDTRYFDEEFTAQMI---------------SERRPH---FPQFDYSAS---
29 PsiBlast_CBE 48.2583% -61 - C1 -2JDO AKT2_HUMAN A:[6-340] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---K---A---T-G----RYYAMKILRKEVIIAKDEVAHTVTESRV-LQ--NT-RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E----RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDGHIKITDFGLCKEGISDGAT-MK---FCGTPEYLAPEVLE-----DN---DYGRAVDWWGLGVVMYEMMCG-RLPFY--N---Q----DHERLFELILME--EIRFP-RT---LSPEAKSLLAGLLKKDPKQRLGG-GP-SDAKEVMEHRFFLSIN---WQDVVQKKLLPPFKPQVTS-----EVDTRYFDDEFTAQSIT--------------------M--FEDFDYIA----
86 PsiBlast_CBE 47.9445%-100 - C1 -4EL9 KS6A3_MOUSE A:[25-305] ---------------------------------------------------------------------------------------------------------------------------------------------------SQFELLKVLGQG-SFGKVFLVK----K---I---S-GSDARQLYAMKVLKKATLKVRDRV-R-----DI-LV--EV-NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK-E----VMFTEEDVKFYLAELALALDHLHS-LGIIYRDLKPENILLD-EEGHIKLTDFGLSKES---EKK-AY--SFCGTVEYMAPEVVN-----RR---GHTQSADWWSFGVLMFEMLTG-TLPFQ--G---K----DRKETMTMILKA--KLGMP-QF---LSPEAQSLLRMLFKRNPANRLGA-GP-DGVEEIKRHSFFSTID---WNKLYRREIHPPFKP-------------------------------------------------------------
84 PsiBlast_CBE 47.8745%-101 - C1 -3UBD KS6A3_MOUSE A:[24-304] ---------------------------------------------------------------------------------------------------------------------------------------------------SQFELLKVLGQG-SFGKVFLVK----K---I---S-GSDARQLYAMKVLKKATLKVRDRV-------DI-LV--EV-NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK-E----VMFTEEDVKFYLAELALALDHLHS-LGIIYRDLKPENILLD-EEGHIKLTDFGLSKE-----KK-AY--SFCGTVEYMAPEVVN-----RR---GHTQSADWWSFGVLMFEMLTG-TLPFQ--G---K----DRKETMTMILKA--KLGMP-QF---LSPEAQSLLRMLFKRNPANRLGA-GP-DGVEEIKRHSFFSTID---WNKLYRREIHPPFKP-------------------------------------------------------------