@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : KPCZ_HUMAN: (2013-07-22 )
MPSRTGPKMEGSGGRVRLKAHYGGDIFITSVDAATTFEELCEEVRDMCRLHQQHPLTLKWVDSEGDPCTVSSQMELEEAFRLARQCRDEGLIIHVFPSTPEQPGLPCPGEDKSIYRRGARRWRKLYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTCRKHMDSVMPSQEPPVDDKNEDADLPSEETDGIAYISSSRKHDSIKDDSEDLKPVIDGMDGIKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNFDTQFTSEPVQLTPDDEDAIKRIDQSEFEGFEYINPLLLSTEESV
Atome Classification :
(60 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190-----------------.........200...---------------....----.210-----------------------------------....---..----------------...220-------.......230.......240.......250.......260.......270---.---...--....280.......290.......300.......310.......320.......330.......340..--.....350.......360......-.370.......380.......390.......400.....-.-.410-.......420..-----...-----..430.......440.......450..--.....460.......470.--......--480-.........490.......500..-----.....510.......520.......530.......540......-.550.-.......560.....----..570-.......580.......590
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MPSRTGPKMEGSGGRVRLKAHYGGDIFITSVDAATTFEELCEEVRDMCRLHQQHPLTLKWVDSEGDPCTVSSQMELEEAFRLARQCRDEGLIIHVFPSTPEQPGLPCPGEDKSIYRRGARRWRKLYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTCRKHMDSVMPS-------------------QEPPVDDKNE-DADL---------------PSEE----TD-------------------------------------GIAY---IS----------------SSRKHD-------SIKDDSEDLKPVIDGMDGIKISQGLGLQDFDLIRVIGRGSYAKVLLVR-L---K---KND--QIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQR--QRKLPEEHARFYAAEICIALNFLH-ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDT-T-STFC-GTPNYIAPEILR-----GEE-----YGFSVDWWALGVLMFEMMAGRSPFDII--TDNPDMNTEDYLFQVILEK--PIRIPR--F---LSVKASHVLKGFLNKDPKERLGCR-----PQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF-DT-QF-TSEPVQLTPDDEDAI----KRIDQ-SEFEGFEYINPLLLSTEESV
87
HHSearch
89.39
83%
-127
- C2 -
4DC2
1
KPCI_MOUSE
A:
[49-387]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
L
Q
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F
D
L
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I
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R
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Y
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-
L
---
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---
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--
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A
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-
E
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I
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GS------
N
T
E
D
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E
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--
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--
S
---
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A
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E
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-----
P
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-
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S
-
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D
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----
R
K
I
D
Q
-
S
E
F
E
G
F
E
Y
I
N
P
---------
4
PsiBlast_PDB
89.11
84%
-127
- C2 -
3A8W
1
KPCI_HUMAN
A:
[6-345]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
L
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-
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---
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---
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----
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A
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L
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-
E
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-----
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A
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-----------
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--
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---
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A
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-----
P
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-
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-
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----
R
K
I
D
Q
-
S
E
F
E
G
F
E
Y
I
N
P
L
--------
2
PsiBlast_PDB
86.16
84%
-122
- C2 -
3ZH8
4
KPCI_HUMAN
A:
[2-343]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
L
Q
D
F
D
L
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-
L
---
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---
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A
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-
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-----
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Y
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M
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A
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--------
N
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E
D
Y
L
F
Q
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I
L
E
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--
Q
I
R
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R
--
S
---
L
S
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A
A
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F
L
N
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-----
P
Q
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E
------------------
Q
L
T
P
D
D
D
D
I
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----
R
K
I
D
Q
-
S
E
F
E
G
F
E
Y
I
N
P
L
L
M
------
86
HHSearch
85.02
44%
-107
- C2 -
3PFQ
1
KPCB_RAT
A:
[102-670]
---------------------------------------------------------------------------------------------------------------------------------
K
H
K
F
K
I
H
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Y
S
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C
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A
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RE
V
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I
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V
V
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D
A
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L
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P
M
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P
N
G
-
L
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Y
V
K
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L
I
PDPKSES
K
Q
K
T
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T
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K
S
S
L
NPEWN
E
T
F
R
F
QLKESDKD
R
R
L
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V
E
I
W
D
W
D
LTSR
N
D
F
M
G
S
L
S
---
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G
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F
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V
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V
P
P
-------------------------
L
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A
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A
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P
-
E
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----
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S
E
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E
G
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F
V
N
S
E
F
L
K
P
----
18
PsiBlast_PDB
74.91
45%
-119
- C2 -
3E88
1
AKT2_HUMAN
A:
[4-330]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
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---
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--
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A
-
K
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---------------
Q
R
T
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F
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Q
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Y
------------
95
HHSearch
74.60
47%
-123
- C2 -
1O6L
1
AKT2_HUMAN
A:
[1-336]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
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--
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A
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L
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-
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-
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E
-----
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-----
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G
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M
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I
L
M
E
--
E
I
R
F
P
R
--
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
R
L
G
G
G
-----
P
S
-
D
A
K
E
V
M
E
H
R
F
F
L
S
I
N
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
-
D
D
-
E
F
-
T
A
Q
S
I
T
-----------------
Q
-
E
M
F
E
D
F
D
Y
I
A
D
---------
19
PsiBlast_PDB
74.36
45%
-118
- C2 -
3D0E
1
AKT2_HUMAN
A:
[4-330]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
-
E
---
K
---
A
T
G
--
R
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
-
Q
N
T
R
H
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
-
S
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
S
D
G
A
T
-
M
-
K
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
------
Y
N
Q
D
---
H
E
R
L
F
E
L
I
L
M
E
--
E
I
R
F
P
R
--
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
R
L
G
G
G
-----
P
S
D
A
-
K
E
V
M
E
H
R
F
F
L
S
I
N
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
-
D
D
-
E
F
-
T
A
Q
S
I
T
I
T
P
P
D
------------
Q
R
T
H
F
P
Q
F
D
Y
------------
90
HHSearch
74.15
44%
-122
- C2 -
4GV1
5
AKT1_HUMAN
A:
[3-337]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
V
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
-
E
---
K
---
A
T
G
--
R
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
K
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
N
S
-
R
H
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
K
D
G
A
T
-
M
-
K
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
---------
Y
N
Q
D
H
E
K
L
F
E
L
I
L
M
E
--
E
I
R
F
P
R
--
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
L
G
G
G
-----
S
E
-
D
A
K
E
I
M
Q
H
R
F
F
A
G
I
V
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
-
D
E
-
E
F
-
T
A
Q
M
I
T
I
T
P
-----
S
MECV
D
S
E
R
R
-
P
H
F
P
Q
F
D
Y
S
A
S
---------
11
PsiBlast_PDB
73.92
46%
-114
- C2 -
2JDR
1
AKT2_HUMAN
A:
[9-339]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
-
E
---
K
---
A
T
G
--
R
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
-
Q
N
T
R
H
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
-
S
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
S
D
G
A
T
-
M
-
K
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
------
Y
N
Q
D
---
H
E
R
L
F
E
L
I
L
M
E
--
E
I
R
F
P
R
--
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
R
L
G
G
G
-----
P
S
D
A
-
K
E
V
M
E
H
R
F
F
L
S
I
N
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
-
D
D
-
E
F
-
T
A
Q
S
I
T
-----------------
Q
-
E
M
F
E
D
F
D
Y
I
-----------
14
PsiBlast_PDB
73.64
46%
-118
- C2 -
2XH5
1
AKT2_HUMAN
A:
[9-339]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
-
E
---
K
---
A
T
G
--
R
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
-
Q
N
T
R
H
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
-
S
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
S
D
G
A
T
-
M
-
K
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
------
Y
N
Q
D
---
H
E
R
L
F
E
L
I
L
M
E
--
E
I
R
F
P
R
--
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
R
L
G
G
G
-----
P
S
D
A
-
K
E
V
M
E
H
R
F
F
L
S
I
N
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
-
D
D
-
E
F
-
T
A
Q
S
I
T
-----------------
Q
-
E
M
F
E
D
F
D
Y
I
-----------
10
PsiBlast_PDB
73.47
46%
-119
- C2 -
2JDO
2
AKT2_HUMAN
A:
[9-339]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
-
E
---
K
---
A
T
G
--
R
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
-
Q
N
T
R
H
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
-
S
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
S
D
G
A
T
-
M
-
K
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
------
Y
N
Q
D
---
H
E
R
L
F
E
L
I
L
M
E
--
E
I
R
F
P
R
--
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
R
L
G
G
G
-----
P
S
D
A
-
K
E
V
M
E
H
R
F
F
L
S
I
N
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
-
D
D
-
E
F
-
T
A
Q
S
I
T
--------------------
M
F
E
D
F
D
Y
I
-----------
16
PsiBlast_PDB
72.60
45%
-116
- C2 -
1O6K
1
AKT2_HUMAN
A:
[4-330]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
-
E
---
K
---
A
T
G
--
R
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
-
Q
N
T
R
H
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
-
S
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
S
D
G
A
T
-
M
-
K
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
------
Y
N
Q
D
---
H
E
R
L
F
E
L
I
L
M
E
--
E
I
R
F
P
R
--
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
R
L
G
G
G
-----
P
S
D
A
-
K
E
V
M
E
H
R
F
F
L
S
I
N
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
-
D
D
-
E
F
-
T
A
Q
S
I
T
-----------------
Q
R
T
H
F
P
Q
F
D
Y
------------
17
PsiBlast_PDB
72.34
45%
-120
- C2 -
3E87
1
AKT2_HUMAN
A:
[4-330]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
-
E
---
K
---
A
T
G
--
R
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
-
Q
N
T
R
H
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
-
S
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
S
D
G
A
T
-
M
-
K
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
------
Y
N
Q
D
---
H
E
R
L
F
E
L
I
L
M
E
--
E
I
R
F
P
R
--
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
R
L
G
G
G
-----
P
S
D
A
-
K
E
V
M
E
H
R
F
F
L
S
I
N
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
-
D
D
-
E
F
-
T
A
Q
S
I
T
I
T
P
P
-------------
Q
R
T
H
F
P
Q
F
D
Y
------------
13
PsiBlast_PDB
71.86
46%
-117
- C2 -
2X39
1
AKT2_HUMAN
A:
[9-339]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
-
E
---
K
---
A
T
G
--
R
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
-
Q
N
T
R
H
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
-
S
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
S
D
G
A
T
-
M
-
K
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
------
Y
N
Q
D
---
H
E
R
L
F
E
L
I
L
M
E
--
E
I
R
F
P
R
--
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
R
L
G
G
G
-----
P
S
D
A
-
K
E
V
M
E
H
R
F
F
L
S
I
N
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
-
D
D
-
E
F
-
T
A
Q
S
I
T
-----------------
Q
-
E
M
F
E
D
F
D
Y
I
-----------
12
PsiBlast_PDB
69.90
46%
-115
- C2 -
2UW9
1
AKT2_HUMAN
A:
[9-339]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
D
F
D
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
R
-
E
---
K
---
A
T
G
--
R
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
K
D
E
V
A
H
T
V
T
E
S
R
V
L
-
Q
N
T
R
H
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
-
S
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
S
D
G
A
T
-
M
-
K
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
------
Y
N
Q
D
---
H
E
R
L
F
E
L
I
L
M
E
--
E
I
R
F
P
R
--
T
---
L
S
P
E
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
R
L
G
G
G
-----
P
S
D
A
-
K
E
V
M
E
H
R
F
F
L
S
I
N
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
-
D
D
-
E
F
-
T
A
Q
S
I
T
-----------------
Q
-
E
M
F
E
D
F
D
Y
I
-----------
89
HHSearch
69.37
51%
-116
- C2 -
3TXO
1
KPCL_HUMAN
A:
[23-349]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
F
E
F
I
R
V
L
G
K
G
S
F
G
K
V
M
L
A
R
-
V
---
K
---
E
T
G
--
D
L
Y
A
V
K
V
L
K
K
D
V
I
L
Q
D
D
D
V
E
C
T
M
T
E
K
R
I
L
S
L
A
R
N
H
P
F
L
T
Q
L
F
C
C
F
Q
T
P
D
R
L
F
F
V
M
E
F
V
N
G
G
D
L
M
F
H
I
Q
K
--
S
R
R
F
D
E
A
R
A
R
F
Y
A
A
E
I
I
S
A
L
M
F
L
H
-
D
K
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
H
E
G
H
C
K
L
A
D
F
G
M
C
K
E
G
I
C
------------
G
T
P
D
Y
I
A
P
E
I
L
Q
-----
E
M
L
-----
Y
G
P
A
V
D
W
W
A
M
G
V
L
L
Y
E
M
L
C
G
H
A
P
F
---------
E
A
E
N
E
D
D
L
F
E
A
I
L
N
D
--
E
V
V
Y
P
T
--
W
---
L
H
E
D
A
T
G
I
L
K
S
F
M
T
K
N
P
T
M
R
L
G
S
L
-----
T
Q
G
G
E
H
A
I
L
R
H
P
F
F
K
E
I
D
W
A
Q
L
N
H
R
Q
I
E
P
P
F
R
P
R
I
K
S
R
E
D
V
S
N
F
-
D
P
-
D
F
-
I
K
E
E
P
V
L
T
P
I
D
E
G
H
L
----
P
M
I
N
Q
-
D
E
F
R
N
F
E
Y
V
S
P
---------
94
HHSearch
69.24
45%
-119
- C2 -
1XJD
1
A:
[16-335]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
D
F
I
L
H
K
M
L
G
K
G
S
F
G
K
V
F
L
A
E
-
F
---
K
---
K
T
N
--
Q
F
F
A
I
K
A
L
K
K
D
V
V
L
M
D
D
D
V
E
C
T
M
V
E
K
R
V
L
S
L
A
W
E
H
P
F
L
T
H
M
F
C
T
F
Q
T
K
E
N
L
F
F
V
M
E
Y
L
N
G
G
D
L
M
Y
H
I
Q
S
--
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
L
Q
F
L
H
-
S
K
G
I
V
Y
R
D
L
K
L
D
N
I
L
L
D
K
D
G
H
I
K
I
A
D
F
G
M
C
K
E
N
M
L
G
D
A
K
-
T
-
N
T
F
C
-
G
T
P
D
Y
I
A
P
E
I
L
L
-----
G
Q
K
-----
Y
N
H
S
V
D
W
W
S
F
G
V
L
L
Y
E
M
L
I
G
Q
S
P
F
---------
H
G
Q
D
E
E
E
L
F
H
S
I
R
M
D
--
N
P
F
Y
P
R
--
W
---
L
E
K
E
A
K
D
L
L
V
K
L
F
V
R
E
P
E
K
R
L
G
V
R
----------
G
D
I
R
Q
H
P
L
F
R
E
I
N
W
E
E
L
E
R
K
E
I
D
P
---------------------------------------------
Q
-
N
M
F
R
N
F
S
F
------------
24
PsiBlast_CBE
68.68
46%
-122
- C2 -
4EJN
3
AKT1_HUMAN
A:
[147-438]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
-
E
---
K
---
A
T
G
--
R
Y
Y
A
M
K
I
L
K
K
E
V
I
V
-------------
V
L
-
Q
N
S
R
H
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
K
-------
K
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
------
Y
N
Q
D
---
H
E
K
L
F
E
L
I
L
M
E
--
E
I
R
F
P
R
--
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
L
G
G
G
-----
S
E
D
A
-
K
E
I
M
Q
H
R
F
F
A
G
I
V
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
----------------------------------------------------
101
HHSearch
68.10
37%
-109
- C2 -
1RDQ
3
KAPCA_MOUSE
E:
[35-350]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
N
T
A
Q
L
D
Q
F
D
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
-
H
---
K
---
E
S
G
--
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
A
V
-
N
F
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
-
S
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
---
K
G
R
-
T
-
W
T
L
C
-
G
T
P
E
A
L
A
P
E
I
I
L
-----
S
K
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
---------
F
A
D
Q
P
I
Q
I
Y
E
K
I
V
S
G
--
K
V
R
F
P
S
--
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
N
L
------
K
N
G
V
N
D
I
K
N
H
K
W
F
A
T
T
D
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
-
D
--
D
Y
-
E
E
E
E
I
R
V
S
I
N
E
K
----------
C
G
-
K
E
F
T
E
F
--------------
25
PsiBlast_CBE
67.30
46%
-128
- C2 -
3O96
1
AKT1_HUMAN
A:
[150-432]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
E
F
E
Y
L
K
L
L
G
K
G
T
F
G
K
V
I
L
V
K
-
E
---
K
---
A
T
G
--
R
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
----------
N
R
V
L
-
Q
N
S
R
H
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
--
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
G
H
I
K
I
T
D
F
G
L
C
K
E
-----------------
P
E
Y
L
A
P
E
V
L
E
-----
D
N
D
-----
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
L
P
F
------
Y
N
Q
D
---
H
E
K
L
F
E
L
I
L
M
E
--
E
I
R
F
P
R
--
T
---
L
G
P
E
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
L
G
G
G
-----
S
E
D
A
-
K
E
I
M
Q
H
R
F
F
A
G
I
V
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
-------------------------------------------------------------
45
PsiBlast_CBE
67.03
38%
-114
- C2 -
2F7E
1
KAPCA_BOVIN
E:
[41-329]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
-
H
---
M
---
E
T
G
--
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
-
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
-
S
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
---
R
-
T
-
W
T
L
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
--
F
--
A
D
Q
P
I
Q
-----
I
Y
E
K
I
V
S
G
--
K
V
R
F
P
S
--
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
-
N
-----
L
K
N
G
V
N
D
I
K
N
H
K
W
F
A
T
T
D
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
-
D
--------------------------------------------------
99
HHSearch
65.84
41%
-127
- C2 -
3UBD
1
KS6A3_MOUSE
A:
[20-304]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
D
P
S
Q
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
-
K
ISG
S
---
D
A
R
--
Q
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
R
D
-
R
V
------
D
I
L
V
E
-
V
N
H
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
-
S
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
-----
K
K
-
A
-
Y
S
F
C
-
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
G
-----
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
---------
Q
G
K
D
R
K
E
T
M
T
M
I
L
K
A
--
K
L
G
M
P
Q
--
F
---
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
R
L
G
A
G
-----
P
-
D
G
V
E
E
I
K
R
H
S
F
F
S
T
I
D
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
---------------------------------------------------------------
41
PsiBlast_CBE
65.47
38%
-115
- C2 -
2OJF
1
KAPCA_BOVIN
E:
[41-329]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
-
H
---
M
---
E
T
G
--
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
-
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
-
S
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
---
R
-
T
-
W
T
L
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
--
F
--
A
D
Q
P
I
Q
-----
I
Y
E
K
I
V
S
G
--
K
V
R
F
P
S
--
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
-
N
-----
L
K
N
G
V
N
D
I
K
N
H
K
W
F
A
T
T
D
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
-
D
--------------------------------------------------
93
HHSearch
64.84
43%
-128
- C2 -
2R5T
1
SGK1_HUMAN
A:
[32-320]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
P
H
A
K
P
S
D
F
H
F
L
K
V
I
G
K
G
S
F
G
K
V
L
L
A
R
-
H
---
K
---
A
E
E
--
V
F
Y
A
V
K
V
L
Q
K
K
A
I
L
-------------
V
L
L
K
N
V
K
H
P
F
L
V
G
L
H
F
S
F
Q
T
A
D
K
L
Y
F
V
L
D
Y
I
N
G
G
E
L
F
Y
H
L
Q
R
--
E
R
C
F
L
E
P
R
A
R
F
Y
A
A
E
I
A
S
A
L
G
Y
L
H
-
S
L
N
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
S
Q
G
H
I
V
L
T
D
F
G
L
C
K
E
N
I
E
H
N
S
T
-
T
-
S
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
H
-----
K
Q
P
-----
Y
D
R
T
V
D
W
W
C
L
G
A
V
L
Y
E
M
L
Y
G
L
P
P
F
---------
Y
S
R
N
T
A
E
M
Y
D
N
I
L
N
K
--
P
L
Q
L
K
P
--
N
---
I
T
N
S
A
R
H
L
L
E
G
L
L
Q
K
D
R
T
K
R
L
G
A
K
-------
D
D
F
M
E
I
K
S
H
V
F
F
S
L
I
N
W
D
D
L
I
N
K
K
I
T
P
P
F
N
P
N
V
S
G
-----------------------------------------------------------
46
PsiBlast_CBE
64.74
38%
-114
- C2 -
2UZW
1
KAPCA_BOVIN
E:
[26-314]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
-
H
---
M
---
E
T
G
--
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
-
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
-
S
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
---
R
-
T
-
W
T
L
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
--
F
--
A
D
Q
P
I
Q
-----
I
Y
E
K
I
V
S
G
--
K
V
R
F
P
S
--
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
-
N
-----
L
K
D
G
V
N
D
I
K
N
H
K
W
F
A
T
T
D
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
-
D
--------------------------------------------------
49
PsiBlast_CBE
64.54
38%
-117
- C2 -
2UZT
1
KAPCA_BOVIN
A:
[26-314]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
-
H
---
M
---
E
T
G
--
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
-
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
-
S
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
---
R
-
T
-
W
T
L
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
--
F
--
A
D
Q
P
I
Q
-----
I
Y
E
K
I
V
S
G
--
K
V
R
F
P
S
--
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
-
N
-----
L
K
D
G
V
N
D
I
K
N
H
K
W
F
A
T
T
D
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
-
D
--------------------------------------------------
107
HHSearch
64.31
39%
-118
* C2 *
3A62
1
KS6B1_HUMAN
A:
[13-300]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
R
P
E
C
F
E
L
L
R
V
L
G
K
G
G
Y
G
K
V
F
Q
V
R
-
K
---
V
TGA
N
T
G
--
K
I
F
A
M
K
V
L
K
-------------
K
A
E
R
N
I
L
E
E
V
-
K
H
P
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
-
Q
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
H
Q
G
H
V
K
L
T
D
F
G
L
C
------------
H
T
F
C
-
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
A
P
P
F
---------
T
G
E
N
R
K
K
T
I
D
K
I
L
K
C
--
K
L
N
L
P
P
--
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
R
L
G
A
G
-----
P
G
-
D
A
G
E
V
Q
A
H
P
F
F
R
H
I
N
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
--------------------------------------------------------------
44
PsiBlast_CBE
64.09
38%
-113
- C2 -
2F7X
1
KAPCA_BOVIN
E:
[41-329]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
-
H
---
M
---
E
T
G
--
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
-
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
-
S
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
---
R
-
T
-
W
T
L
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
--
F
--
A
D
Q
P
I
Q
-----
I
Y
E
K
I
V
S
G
--
K
V
R
F
P
S
--
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
-
N
-----
L
K
N
G
V
N
D
I
K
N
H
K
W
F
A
T
T
D
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
-
D
--------------------------------------------------
100
HHSearch
64.04
35%
-109
- C2 -
4AW2
3
MRCKA_RAT
A:
[69-411]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
L
H
R
E
D
F
E
I
L
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
-
L
---
K
---
N
A
D
--
K
V
F
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
N
G
-
D
S
K
W
I
T
T
L
H
Y
A
F
Q
D
D
N
N
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F
-
E
D
R
L
P
E
E
M
A
R
F
Y
L
A
E
M
V
I
A
I
D
S
V
H
-
Q
L
H
Y
V
H
R
D
I
K
P
D
N
I
L
M
D
M
N
G
H
I
R
L
A
D
F
G
S
C
L
K
L
M
E
D
G
T
V
Q
S
-
S
V
A
V
-
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
GG
K
G
R
-----
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
---------
Y
A
E
S
L
V
E
T
Y
G
K
I
M
N
H
KE
R
F
Q
F
P
T
--
Q
VTD
V
S
E
N
A
K
D
L
I
R
R
L
I
C
S
R
-
E
H
R
L
G
Q
--------
N
G
I
E
D
F
K
K
H
P
F
F
S
G
I
D
W
D
N
I
--
R
N
C
E
A
P
Y
I
P
E
V
S
S
P
T
D
T
S
N
F
-
D
V
-
D
----------------------
S
G
H
H
-
L
P
F
V
G
F
T
Y
T
S
S
C
V
L
S
D
----
48
PsiBlast_CBE
64.00
38%
-111
- C2 -
2UZU
1
KAPCA_BOVIN
E:
[26-314]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
-
H
---
M
---
E
T
G
--
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
-
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
-
S
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
---
R
-
T
-
W
T
L
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
--
F
--
A
D
Q
P
I
Q
-----
I
Y
E
K
I
V
S
G
--
K
V
R
F
P
S
--
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
-
N
-----
L
K
D
G
V
N
D
I
K
N
H
K
W
F
A
T
T
D
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
-
D
--------------------------------------------------
43
PsiBlast_CBE
63.99
38%
-121
- C2 -
2F7Z
1
KAPCA_BOVIN
E:
[41-329]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
-
H
---
M
---
E
T
G
--
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
-
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
-
S
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
---
R
-
T
-
W
T
L
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
--
F
--
A
D
Q
P
I
Q
-----
I
Y
E
K
I
V
S
G
--
K
V
R
F
P
S
--
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
-
N
-----
L
K
N
G
V
N
D
I
K
N
H
K
W
F
A
T
T
D
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
-
D
--------------------------------------------------
42
PsiBlast_CBE
63.90
38%
-117
- C2 -
2OH0
1
KAPCA_BOVIN
E:
[41-329]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
-
H
---
M
---
E
T
G
--
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
-
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
-
S
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
---
R
-
T
-
W
T
L
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
--
F
--
A
D
Q
P
I
Q
-----
I
Y
E
K
I
V
S
G
--
K
V
R
F
P
S
--
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
-
N
-----
L
K
N
G
V
N
D
I
K
N
H
K
W
F
A
T
T
D
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
-
D
--------------------------------------------------
47
PsiBlast_CBE
61.63
38%
-107
- C2 -
2UZV
1
KAPCA_BOVIN
A:
[26-314]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
-
H
---
M
---
E
T
G
--
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
-
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
--
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
-
S
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
---
R
-
T
-
W
T
L
C
-
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
K
G
-----
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
--
F
--
A
D
Q
P
I
Q
-----
I
Y
E
K
I
V
S
G
--
K
V
R
F
P
S
--
H
---
F
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
-
N
-----
L
K
D
G
V
N
D
I
K
N
H
K
W
F
A
T
T
D
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
-
D
--------------------------------------------------
35
PsiBlast_CBE
60.14
38%
-119
- C2 -
2Z7R
1
KS6A1_HUMAN
A:
[30-308]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
R
K
V
---
T
---
R
P
D
SG
H
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
------------
I
L
A
D
V
N
-
H
P
F
V
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
G
L
D
H
L
H
-
S
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
---------------
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
Q
G
-----
H
S
H
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
S
L
P
F
Q
G
K
--
D
R
K
E
T
M
T
-------
L
I
L
K
A
--
K
L
G
M
P
Q
--
F
---
L
S
T
E
A
Q
S
L
L
R
A
L
F
K
R
N
P
A
N
R
L
G
S
G
-----
P
D
-
G
A
E
E
I
K
R
H
V
F
Y
S
T
I
D
W
N
K
L
Y
R
R
E
I
K
P
P
F
K
P
---------------------------------------------------------------
83
PsiBlast_CBE
60.02
31%
-93
- C2 -
2H9V
1
ROCK2_BOVIN
A:
[46-400]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
R
K
N
K
-------
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
----
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
-
H
---
K
---
A
S
Q
--
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
-
P
W
V
V
Q
L
F
C
A
F
Q
D
D
K
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
-
N
L
M
S
--
N
Y
D
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
-
S
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
T
C
M
K
M
D
E
T
G
M
V
-
H
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
-----
S
Q
G
GD
G
Y
-
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
F
E
M
L
V
G
D
T
P
F
Y
A
-------
D
S
L
V
G
T
Y
S
K
I
M
D
H
K
N
--
S
L
C
F
P
E
D
A
E
---
I
S
K
H
A
K
N
L
I
C
A
F
L
T
-
D
R
E
V
R
L
G
--------
R
N
G
V
E
E
I
K
Q
H
P
F
F
K
N
D
Q
W
N
W
D
N
I
R
E
T
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
I
-
E
-----------
I
P
K
A
F
V
----
G
--
N
Q
-
L
P
F
I
G
F
T
Y
------------
34
PsiBlast_CBE
59.45
38%
-119
- C2 -
2Z7S
1
KS6A1_HUMAN
A:
[30-308]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
R
K
V
---
T
---
R
P
D
SG
H
L
Y
A
M
K
V
L
K
------------------
I
L
A
D
V
N
-
H
P
F
V
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
G
L
D
H
L
H
-
S
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
---------------
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
Q
G
-----
H
S
H
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
S
L
P
F
Q
G
K
--
D
R
K
E
T
M
T
-------
L
I
L
K
A
--
K
L
G
M
P
Q
--
F
---
L
S
T
E
A
Q
S
L
L
R
A
L
F
K
R
N
P
A
N
R
L
G
S
G
-----
P
D
-
G
A
E
E
I
K
R
H
V
F
Y
S
T
I
D
W
N
K
L
Y
R
R
E
I
K
P
P
F
K
P
---------------------------------------------------------------
27
PsiBlast_CBE
59.26
43%
-119
- C2 -
3HDM
1
SGK1_HUMAN
A:
[39-320]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
H
F
L
K
V
I
G
K
G
S
F
G
K
V
L
L
A
R
-
H
---
K
---
A
E
E
--
V
F
Y
A
V
K
V
L
Q
K
K
A
I
L
-------------
V
L
L
K
N
V
K
H
P
F
L
V
G
L
H
F
S
F
Q
T
A
D
K
L
Y
F
V
L
D
Y
I
N
G
G
E
L
F
Y
H
L
Q
R
--
E
R
C
F
L
E
P
R
A
R
F
Y
A
A
E
I
A
S
A
L
G
Y
L
H
-
S
L
N
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
S
Q
G
H
I
V
L
T
D
F
G
L
C
K
E
N
I
E
H
N
S
T
-
T
-
S
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
H
-----
K
Q
P
-----
Y
D
R
T
V
D
W
W
C
L
G
A
V
L
Y
E
M
L
Y
G
L
P
P
F
Y
--------
S
R
N
T
A
E
-
M
Y
D
N
I
L
N
K
--
P
L
Q
L
K
P
--
N
---
I
T
N
S
A
R
H
L
L
E
G
L
L
Q
K
D
R
T
K
R
L
G
A
K
-------
D
D
F
M
E
I
K
S
H
V
F
F
S
L
I
N
W
D
D
L
I
N
K
K
I
T
P
P
F
N
P
N
V
S
G
-----------------------------------------------------------
26
PsiBlast_CBE
59.17
43%
-120
- C2 -
3HDN
1
SGK1_HUMAN
A:
[39-316]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
H
F
L
K
V
I
G
K
G
S
F
G
K
V
L
L
A
R
-
H
---
K
---
A
E
E
--
V
F
Y
A
V
K
V
L
Q
K
K
A
I
L
-------------
V
L
L
K
N
V
K
H
P
F
L
V
G
L
H
F
S
F
Q
T
A
D
K
L
Y
F
V
L
D
Y
I
N
G
G
E
L
F
Y
H
L
Q
R
--
E
R
C
F
L
E
P
R
A
R
F
Y
A
A
E
I
A
S
A
L
G
Y
L
H
-
S
L
N
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
S
Q
G
H
I
V
L
T
D
F
G
L
C
K
E
N
I
E
H
N
S
T
-
T
-
S
T
F
C
-
G
T
P
E
Y
L
A
P
E
V
L
H
-----
K
Q
P
-----
Y
D
R
T
V
D
W
W
C
L
G
A
V
L
Y
E
M
L
Y
G
L
P
P
F
Y
--------
S
R
N
T
A
E
-
M
Y
D
N
I
L
N
K
--
P
L
Q
L
K
P
--
N
---
I
T
N
S
A
R
H
L
L
E
G
L
L
Q
K
D
R
T
K
R
L
G
A
K
-------
D
D
F
M
E
I
K
S
H
V
F
F
S
L
I
N
W
D
D
L
I
N
K
K
I
T
P
P
F
N
P
---------------------------------------------------------------
22
PsiBlast_CBE
58.96
84%
-71
- C2 -
3A8W
1
KPCI_HUMAN
B:
[6-345]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
L
Q
D
F
D
L
L
R
V
I
G
R
G
S
Y
A
K
V
L
L
V
R
-
L
---
K
---
K
T
D
--
R
I
Y
A
M
K
V
V
K
K
E
L
V
N
D
D
E
D
I
D
W
V
Q
T
E
K
H
V
F
E
Q
A
S
N
H
P
F
L
V
G
L
H
S
C
F
Q
T
E
S
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
--
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
-
E
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
S
E
G
H
I
K
L
T
D
Y
G
M
C
K
E
G
---
G
D
T
-
T
-
S
-
F
C
-
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
D
-----
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
R
S
P
F
D
-----------
T
E
D
Y
L
F
Q
V
I
L
E
K
--
Q
I
R
I
P
R
--
S
---
L
S
V
K
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
R
L
G
C
H
-----
P
Q
T
G
F
A
D
I
Q
G
H
P
F
F
R
N
V
D
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
-
D
S
-
Q
F
-
T
N
E
P
V
Q
L
-
P
D
D
D
D
I
V
----
R
K
I
D
Q
-
S
E
F
E
G
F
E
Y
I
N
P
L
--------
36
PsiBlast_CBE
58.30
38%
-122
- C2 -
2Z7Q
1
KS6A1_HUMAN
A:
[30-308]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
R
K
V
---
T
---
R
P
D
SG
H
L
Y
A
M
K
V
L
-------------------
I
L
A
D
V
N
-
H
P
F
V
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
G
L
D
H
L
H
-
S
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
---------------
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
Q
G
-----
H
S
H
S
A
D
W
W
S
Y
G
V
L
M
F
E
M
L
T
G
S
L
P
F
Q
G
K
--
D
R
K
E
T
M
T
-------
L
I
L
K
A
--
K
L
G
M
P
Q
--
F
---
L
S
T
E
A
Q
S
L
L
R
A
L
F
K
R
N
P
A
N
R
L
G
S
G
-----
P
D
-
G
A
E
E
I
K
R
H
V
F
Y
S
T
I
D
W
N
K
L
Y
R
R
E
I
K
P
P
F
K
P
---------------------------------------------------------------
38
PsiBlast_CBE
57.84
40%
-121
- C2 -
4EL9
1
KS6A3_MOUSE
A:
[27-305]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
K
I
---
S
---
G
S
D
AR
Q
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
R
D
R
V
R
------
D
I
L
V
E
V
N
-
H
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
-
S
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
S
---
E
K
K
-
A
-
Y
S
F
C
-
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
G
-----
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
Q
G
K
--
D
R
K
E
T
M
T
-------
M
I
L
K
A
--
K
L
G
M
P
Q
--
F
---
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
R
L
G
A
G
-----
P
D
-
G
V
E
E
I
K
R
H
S
F
F
S
T
I
D
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
---------------------------------------------------------------
85
PsiBlast_CBE
57.28
31%
-94
- C2 -
2F2U
1
ROCK2_BOVIN
A:
[46-400]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
R
K
N
K
-------
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
----
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
-
H
---
K
---
A
S
Q
--
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
-
P
W
V
V
Q
L
F
C
A
F
Q
D
D
K
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
-
N
L
M
S
--
N
Y
D
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
-
S
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
T
C
M
K
M
D
E
T
G
M
V
-
H
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
-----
S
Q
G
GD
G
Y
-
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
F
E
M
L
V
G
D
T
P
F
Y
A
-------
D
S
L
V
G
T
Y
S
K
I
M
D
H
K
N
--
S
L
C
F
P
E
D
A
E
---
I
S
K
H
A
K
N
L
I
C
A
F
L
T
-
D
R
E
V
R
L
G
--------
R
N
G
V
E
E
I
K
Q
H
P
F
F
K
N
D
Q
W
N
W
D
N
I
R
E
T
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
I
-
E
------
V
E
T
F
P
I
P
K
A
F
V
----
G
--
N
Q
-
L
P
F
I
G
F
T
Y
------------
33
PsiBlast_CBE
56.69
39%
-119
- C2 -
3G51
1
KS6A3_MOUSE
A:
[26-304]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
K
I
---
S
---
G
S
D
AR
Q
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
R
D
----------
I
L
V
E
V
N
-
H
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
-
S
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
S
I
--------------
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
G
-----
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
Q
G
K
--
D
R
K
E
T
M
T
-------
M
I
L
K
A
--
K
L
G
M
P
Q
--
F
---
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
R
L
G
A
G
-----
P
D
-
G
V
E
E
I
K
R
H
S
F
F
S
T
I
D
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
---------------------------------------------------------------
37
PsiBlast_CBE
56.49
40%
-119
- C2 -
4GUE
1
KS6A3_MOUSE
A:
[27-305]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
L
K
V
L
G
Q
G
S
F
G
K
V
F
L
V
K
K
I
---
S
---
G
S
D
AR
Q
L
Y
A
M
K
V
L
K
K
A
T
L
K
V
R
D
R
V
---------
L
V
E
V
N
-
H
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
--
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
-
S
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
G
H
I
K
L
T
D
F
G
L
S
K
E
-----
K
K
-
A
-
Y
S
F
C
-
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
G
-----
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
L
P
F
Q
G
K
--
D
R
K
E
T
M
T
-------
M
I
L
K
A
--
K
L
G
M
P
Q
--
F
---
L
S
P
E
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
R
L
G
A
G
-----
P
D
-
G
V
E
E
I
K
R
H
S
F
F
S
T
I
D
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
---------------------------------------------------------------
30
PsiBlast_CBE
56.46
39%
-109
- C2 -
3A61
1
KS6B1_HUMAN
A:
[19-299]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
L
R
V
L
G
K
G
G
Y
G
K
V
F
Q
V
R
-
K
V
T
G
A
---
N
T
G
--
K
I
F
A
M
K
V
L
K
--------------
A
E
R
N
I
L
E
E
V
K
-
H
P
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
-
Q
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
H
Q
G
H
V
K
L
T
D
F
G
-------------------
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
A
P
P
F
-----
T
G
E
N
R
K
K
T
I
D
K
----
I
L
K
C
--
K
L
N
L
P
P
--
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
R
L
G
A
G
-----
P
G
D
A
-
G
E
V
Q
A
H
P
F
F
R
H
I
N
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
---------------------------------------------------------------
84
PsiBlast_CBE
55.92
31%
-94
- C2 -
2F2U
1
ROCK2_BOVIN
B:
[46-400]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
R
K
N
K
-------
N
I
D
N
F
L
N
R
Y
E
K
I
V
K
K
I
R
G
L
Q
M
K
A
----
E
D
Y
D
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
-
H
---
K
---
A
S
Q
--
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
-
P
W
V
V
Q
L
F
C
A
F
Q
D
D
K
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
-
N
L
M
S
--
N
Y
D
V
P
E
K
W
A
K
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
-
S
M
G
L
I
H
R
D
V
K
P
D
N
M
L
L
D
K
H
G
H
L
K
L
A
D
F
G
T
C
M
K
M
D
E
T
G
M
V
-
H
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
-----
S
Q
G
GDGY-
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
F
E
M
L
V
G
D
T
P
F
Y
A
-------
D
S
L
V
G
T
Y
S
K
I
M
D
H
K
N
--
S
L
C
F
P
E
DA
E
---
I
S
K
H
A
K
N
L
I
C
A
F
L
T
-
D
R
E
V
R
L
G
--------
R
N
G
V
E
E
I
K
Q
H
P
F
F
K
N
D
Q
W
N
W
D
N
I
R
E
T
A
A
P
V
V
P
E
L
S
S
D
I
D
S
S
N
F
D
D
I
----------
T
F
P
I
P
K
A
F
V
----
G
--
N
Q
-
L
P
F
I
G
F
T
Y
------------
32
PsiBlast_CBE
55.63
39%
-107
- C2 -
3A60
1
KS6B1_HUMAN
A:
[19-299]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
L
R
V
L
G
K
G
G
Y
G
K
V
F
Q
V
R
-
K
V
T
G
A
---
N
T
G
--
K
I
F
A
M
K
V
L
K
K
A
M
----------
K
A
E
R
N
I
L
E
E
V
K
-
H
P
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
-
Q
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
H
Q
G
H
V
K
L
T
D
F
G
L
C
K
E
----------------
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
A
P
P
F
-----
T
G
E
N
R
K
K
T
I
D
K
----
I
L
K
C
--
K
L
N
L
P
P
--
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
R
L
G
A
G
-----
P
G
D
A
-
G
E
V
Q
A
H
P
F
F
R
H
I
N
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
---------------------------------------------------------------
56
PsiBlast_CBE
54.18
34%
-93
- C2 -
3TKU
3
MRCKB_HUMAN
A:
[90-388]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
-
M
---
K
---
N
T
E
--
R
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
N
G
D
C
Q
-
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F
-
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
-
Q
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
S
C
L
K
M
N
D
D
G
T
V
-
Q
-
S
S
V
A
V
G
T
P
D
Y
I
S
P
E
I
L
Q
-----
A
M
E
D
G
M
G
K
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-------
Y
A
E
S
L
V
E
T
Y
G
K
I
M
N
H
E
E
--
R
F
Q
F
P
S
--
H
---
V
T
D
V
S
E
E
A
------
K
D
L
I
Q
R
L
I
C
S
RERRL
G
Q
N
G
I
E
D
F
K
K
H
A
F
F
E
G
L
N
W
E
N
I
R
N
L
E
A
--
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
-
D
V
-------------------------------------------------
55
PsiBlast_CBE
53.90
34%
-97
- C2 -
3QFV
2
MRCKB_HUMAN
A:
[74-372]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
F
E
I
I
K
V
I
G
R
G
A
F
G
E
V
A
V
V
K
-
M
---
K
---
N
T
E
--
R
I
Y
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
N
G
D
C
Q
-
W
I
T
A
L
H
Y
A
F
Q
D
E
N
H
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F
-
E
D
K
L
P
E
D
M
A
R
F
Y
I
G
E
M
V
L
A
I
D
S
I
H
-
Q
L
H
Y
V
H
R
D
I
K
P
D
N
V
L
L
D
V
N
G
H
I
R
L
A
D
F
G
S
C
L
K
M
N
D
D
G
T
V
-
Q
-
S
S
V
A
V
G
T
P
D
Y
I
S
P
E
I
L
Q
-----
A
M
E
DGMGK
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
-------
Y
A
E
S
L
V
E
T
Y
G
K
I
M
N
H
E
E
--
R
F
Q
F
P
S
--
H
---
V
T
D
V
S
E
E
A
------
K
D
L
I
Q
R
L
I
C
S
RERRL
G
Q
N
G
I
E
D
F
K
K
H
A
F
F
E
G
L
N
W
E
N
I
R
N
L
E
A
--
P
Y
I
P
D
V
S
S
P
S
D
T
S
N
F
-
D
V
-------------------------------------------------
79
PsiBlast_CBE
52.67
31%
-82
- C2 -
2ETK
1
ROCK1_HUMAN
A:
[20-399]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
K
S
E
V
N
S
D
C
---------------
L
L
D
G
----
L
D
-------------------------------------
A
L
V
Y
D
L
D
F
P
----------------
A
L
R
K
N
K
-------
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
----
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
-
H
---
K
---
S
T
R
--
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
-
N
L
M
S
--
N
Y
D
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
-
S
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
T
C
M
K
M
N
K
E
G
M
V
-
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
-----
S
Q
G
GDGY-
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
Y
A
-------
D
S
L
V
G
T
Y
S
K
I
M
N
H
K
N
--
S
L
T
F
P
D
DN
D
---
I
S
K
E
A
K
N
L
I
C
A
F
L
T
-
D
R
E
V
R
L
G
--------
R
N
G
V
E
E
I
K
R
H
L
F
F
K
N
D
Q
W
A
W
E
T
L
R
D
T
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
-
D
D
-
L
E
-
E
D
K
G
E
E
E
T
F
P
I
P
K
A
F
----
V
G
-
N
Q
-
L
P
F
V
G
F
T
Y
------------
75
PsiBlast_CBE
52.22
31%
-81
- C2 -
3D9V
1
ROCK1_HUMAN
A:
[20-399]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
K
S
E
V
N
S
D
C
---------------
L
L
D
G
----
L
D
-------------------------------------
A
L
V
Y
D
L
D
F
P
----------------
A
L
R
K
N
K
-------
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
----
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
-
H
---
K
---
S
T
R
--
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
-
N
L
M
S
--
N
Y
D
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
-
S
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
T
C
M
K
M
N
K
E
G
M
V
-
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
-----
S
Q
G
GDGY-
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
Y
A
-------
D
S
L
V
G
T
Y
S
K
I
M
N
H
K
N
--
S
L
T
F
P
D
DN
D
---
I
S
K
E
A
K
N
L
I
C
A
F
L
T
-
D
R
E
V
R
L
G
--------
R
N
G
V
E
E
I
K
R
H
L
F
F
K
N
D
Q
W
A
W
E
T
L
R
D
T
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
-
D
D
-
L
E
-
E
D
K
G
E
E
E
T
F
P
I
P
K
A
F
----
V
G
-
N
Q
-
L
P
F
V
G
F
T
Y
------------
31
PsiBlast_CBE
51.88
39%
-109
- C2 -
3A60
1
KS6B1_HUMAN
B:
[19-300]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
L
R
V
L
G
K
G
G
Y
G
K
V
F
Q
V
R
-
K
VTG
A
---
N
T
G
--
K
I
F
A
M
K
V
L
K
K
----------------------
K
-
H
P
F
I
V
D
L
I
Y
A
F
Q
T
G
G
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
--
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
-
Q
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
H
Q
G
H
V
K
L
T
D
F
G
L
C
K
E
S
------------
C
-
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
G
-----
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
A
P
P
F
-----
T
G
E
N
R
K
K
T
I
D
K
----
I
L
K
C
--
K
L
N
L
P
P
--
Y
---
L
T
Q
E
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
R
L
G
A
G
-----
P
G
D
A
-
G
E
V
Q
A
H
P
F
F
R
H
I
N
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
--------------------------------------------------------------
77
PsiBlast_CBE
51.41
31%
-77
- C2 -
2ETR
1
ROCK1_HUMAN
A:
[20-399]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
K
S
E
V
N
S
D
C
---------------
L
L
D
G
----
L
D
-------------------------------------
A
L
V
Y
D
L
D
F
P
----------------
A
L
R
K
N
K
-------
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
----
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
-
H
---
K
---
S
T
R
--
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
-
N
L
M
S
--
N
Y
D
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
-
S
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
T
C
M
K
M
N
K
E
G
M
V
-
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
-----
S
Q
G
GDGY-
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
Y
A
-------
D
S
L
V
G
T
Y
S
K
I
M
N
H
K
N
--
S
L
T
F
P
D
DN
D
---
I
S
K
E
A
K
N
L
I
C
A
F
L
T
-
D
R
E
V
R
L
G
--------
R
N
G
V
E
E
I
K
R
H
L
F
F
K
N
D
Q
W
A
W
E
T
L
R
D
T
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
-
D
D
-
L
E
-
E
D
K
G
E
E
E
T
F
P
I
P
K
A
F
----
V
G
-
N
Q
-
L
P
F
V
G
F
T
Y
------------
82
PsiBlast_CBE
51.03
31%
-79
- C2 -
2V55
1
ROCK1_HUMAN
A:
[20-399]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
K
S
E
V
N
S
D
C
---------------
L
L
D
G
----
L
D
-------------------------------------
A
L
V
Y
D
L
D
F
P
----------------
A
L
R
K
N
K
-------
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
----
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
-
H
---
K
---
S
T
R
--
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
-
N
L
M
S
--
N
Y
D
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
-
S
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
T
C
M
K
M
N
K
E
G
M
V
-
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
-----
S
Q
G
GD
G
Y
-
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
Y
A
-------
D
S
L
V
G
T
Y
S
K
I
M
N
H
K
N
--
S
L
T
F
P
D
DN
D
---
I
S
K
E
A
K
N
L
I
C
A
F
L
T
-
D
R
E
V
R
L
G
--------
R
N
G
V
E
E
I
K
R
H
L
F
F
K
N
D
Q
W
A
W
E
T
L
R
D
T
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
-
D
D
-
L
-------
E
E
T
F
P
I
P
K
A
F
----
V
G
-
N
Q
-
L
P
F
V
G
F
T
Y
------------
78
PsiBlast_CBE
50.49
31%
-79
- C2 -
2ETK
1
ROCK1_HUMAN
B:
[20-399]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
K
S
E
V
N
S
D
C
---------------
L
L
D
G
----
L
D
-------------------------------------
A
L
V
Y
D
L
D
F
P
----------------
A
L
R
K
N
K
-------
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
----
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
-
H
---
K
---
S
T
R
--
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
-
N
L
M
S
--
N
Y
D
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
-
S
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
T
C
M
K
M
N
K
E
G
M
V
-
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
-----
S
Q
G
GD
G
Y
-
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
Y
A
-------
D
S
L
V
G
T
Y
S
K
I
M
N
H
K
N
--
S
L
T
F
P
D
DN
D
---
I
S
K
E
A
K
N
L
I
C
A
F
L
T
-
D
R
E
V
R
L
G
--------
R
N
G
V
E
E
I
K
R
H
L
F
F
K
N
D
Q
W
A
W
E
T
L
R
D
T
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
-
D
D
-
L
E
-
E
D
K
G
E
E
E
T
F
P
I
P
K
A
F
----
V
G
-
N
Q
-
L
P
F
V
G
F
T
Y
------------
74
PsiBlast_CBE
49.69
31%
-78
- C2 -
3D9V
1
ROCK1_HUMAN
B:
[20-399]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
K
S
E
V
N
S
D
C
---------------
L
L
D
G
----
L
D
-------------------------------------
A
L
V
Y
D
L
D
F
P
----------------
A
L
R
K
N
K
-------
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
----
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
-
H
---
K
---
S
T
R
--
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
-
N
L
M
S
--
N
Y
D
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
-
S
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
T
C
M
K
M
N
K
E
G
M
V
-
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
-----
S
Q
G
GD
G
Y
-
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
Y
A
-------
D
S
L
V
G
T
Y
S
K
I
M
N
H
K
N
--
S
L
T
F
P
D
DN
D
---
I
S
K
E
A
K
N
L
I
C
A
F
L
T
-
D
R
E
V
R
L
G
--------
R
N
G
V
E
E
I
K
R
H
L
F
F
K
N
D
Q
W
A
W
E
T
L
R
D
T
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
-
D
D
-
L
E
-
E
D
K
G
E
E
E
T
F
P
I
P
K
A
F
----
V
G
-
N
Q
-
L
P
F
V
G
F
T
Y
------------
81
PsiBlast_CBE
49.39
31%
-77
- C2 -
2ESM
1
ROCK1_HUMAN
A:
[20-399]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
K
S
E
V
N
S
D
C
---------------
L
L
D
G
----
L
D
-------------------------------------
A
L
V
Y
D
L
D
F
P
----------------
A
L
R
K
N
K
-------
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
----
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
-
H
---
K
---
S
T
R
--
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
-
N
L
M
S
--
N
Y
D
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
-
S
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
T
C
M
K
M
N
K
E
G
M
V
-
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
-----
S
Q
G
GDGY-
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
Y
A
-------
D
S
L
V
G
T
Y
S
K
I
M
N
H
K
N
--
S
L
T
F
P
D
DN
D
---
I
S
K
E
A
K
N
L
I
C
A
F
L
T
-
D
R
E
V
R
L
G
--------
R
N
G
V
E
E
I
K
R
H
L
F
F
K
N
D
Q
W
A
W
E
T
L
R
D
T
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
-
D
D
-
L
E
-
E
D
K
G
E
E
E
T
F
P
I
P
K
A
F
----
V
G
-
N
Q
-
L
P
F
V
G
F
T
Y
------------
76
PsiBlast_CBE
48.93
31%
-78
- C2 -
2ETR
1
ROCK1_HUMAN
B:
[20-399]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
K
S
E
V
N
S
D
C
---------------
L
L
D
G
----
L
D
-------------------------------------
A
L
V
Y
D
L
D
F
P
----------------
A
L
R
K
N
K
-------
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
----
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
-
H
---
K
---
S
T
R
--
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
-
N
L
M
S
--
N
Y
D
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
-
S
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
T
C
M
K
M
N
K
E
G
M
V
-
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
-----
S
Q
G
GD
G
Y
-
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
Y
A
-------
D
S
L
V
G
T
Y
S
K
I
M
N
H
K
N
--
S
L
T
F
P
D
DN
D
---
I
S
K
E
A
K
N
L
I
C
A
F
L
T
-
D
R
E
V
R
L
G
--------
R
N
G
V
E
E
I
K
R
H
L
F
F
K
N
D
Q
W
A
W
E
T
L
R
D
T
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
-
D
D
-
L
E
-
E
D
K
G
E
E
E
T
F
P
I
P
K
A
F
----
V
G
-
N
Q
-
L
P
F
V
G
F
T
Y
------------
80
PsiBlast_CBE
48.37
31%
-75
- C2 -
2ESM
1
ROCK1_HUMAN
B:
[20-399]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
K
S
E
V
N
S
D
C
---------------
L
L
D
G
----
L
D
-------------------------------------
A
L
V
Y
D
L
D
F
P
----------------
A
L
R
K
N
K
-------
N
I
D
N
F
L
S
R
Y
K
D
T
I
N
K
I
R
D
L
R
M
K
A
----
E
D
Y
E
V
V
K
V
I
G
R
G
A
F
G
E
V
Q
L
V
R
-
H
---
K
---
S
T
R
--
K
V
Y
A
M
K
L
L
S
K
F
E
M
I
K
R
S
D
S
A
F
F
W
E
E
R
D
I
M
A
F
A
N
S
-
P
W
V
V
Q
L
F
Y
A
F
Q
D
D
R
Y
L
Y
M
V
M
E
Y
M
P
G
G
D
L
V
-
N
L
M
S
--
N
Y
D
V
P
E
K
W
A
R
F
Y
T
A
E
V
V
L
A
L
D
A
I
H
-
S
M
G
F
I
H
R
D
V
K
P
D
N
M
L
L
D
K
S
G
H
L
K
L
A
D
F
G
T
C
M
K
M
N
K
E
G
M
V
-
R
C
D
T
A
V
-
G
T
P
D
Y
I
S
P
E
V
L
K
-----
S
Q
G
GD
G
Y
-
Y
G
R
E
C
D
W
W
S
V
G
V
F
L
Y
E
M
L
V
G
D
T
P
F
Y
A
-------
D
S
L
V
G
T
Y
S
K
I
M
N
H
K
N
--
S
L
T
F
P
D
DN
D
---
I
S
K
E
A
K
N
L
I
C
A
F
L
T
-
D
R
E
V
R
L
G
--------
R
N
G
V
E
E
I
K
R
H
L
F
F
K
N
D
Q
W
A
W
E
T
L
R
D
T
V
A
P
V
V
P
D
L
S
S
D
I
D
T
S
N
F
-
D
D
-
L
E
-
E
D
K
G
E
E
E
T
F
P
I
P
K
A
F
----
V
G
-
N
Q
-
L
P
F
V
G
F
T
Y
------------
52
PsiBlast_CBE
29.68
35%
3
- C2 -
3NYO
1
GRK6_HUMAN
A:
[188-502]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
Q
Y
R
V
L
G
K
G
G
F
G
E
V
C
A
C
Q
-
V
---
R
---
A
T
G
--
K
M
Y
A
C
K
K
L
E
K
K
R
I
K
K
R
K
G
E
A
M
A
L
N
E
K
Q
I
L
E
K
V
N
S
R
-
F
V
V
S
L
A
Y
A
Y
E
T
K
D
A
L
C
L
V
L
T
L
M
N
G
G
D
L
K
F
H
I
Y
H
MG
Q
A
G
F
P
E
A
R
A
V
F
Y
A
A
E
I
C
C
G
L
E
D
L
H
-
R
E
R
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
D
H
G
H
I
R
I
S
D
L
G
L
A
V
H
-
V
P
E
G
Q
T
-
I
-
K
G
R
V
-
G
T
V
G
Y
M
A
P
E
V
V
K
-----
N
E
R
-----
Y
T
F
S
P
D
W
W
A
L
G
C
L
L
Y
E
M
I
A
G
Q
S
P
F
Q
--------
K
K
I
K
R
E
E
V
E
R
L
V
K
E
V
--
P
E
E
Y
S
E
--
R
---
F
S
P
Q
A
R
S
L
C
S
Q
L
L
C
K
D
P
A
E
R
L
G
C
R
-----
G
G
S
A
-
R
E
V
K
E
H
P
L
F
K
K
L
N
F
K
R
L
G
A
G
M
L
E
P
P
F
K
P
D
P
Q
A
I
Y
C
K
D
V
L
-
D
I
E
Q
F
S
T
V
K
G
V
E
L
E
P
T
D
Q
D
F
Y
----
Q
K
F
-----------------------