@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0716: (2015-12-04 )
MLAYTTSTHDHILKPFDVSNLESSDVIFYIDDNLETFIKPFAKDKKELVQLSKTINLLPARSHSFSKQITHTQDEKDLHIWLSPENAKSMILSISEALSNIDKENASRYNYNAIKAKKKINQEAEKIAKELNDFKNQKYIVTHDAYQYFEKYFGLNHPSVILSIEEDSYIGMKSLMKLKKVMEEENIKCIFSHSLEDSIKPKVLSNDAKMIILDPIGSNIEPGKDAYLAIINDITQNFKSCFAGYQ
Atome Classification :
(20 SA)
-----------------------------------.........10........20........30....-...-.40----..----....----.---.50.......---.60........------70.....---...80........90........100.......110.......120.......130..--....--.140.......150.......160.......170.......180.......190.......200..-----...-----.-----.------210----.....----...220--..---.......230.......240....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------M
L
A
Y
TTSTHDHILKPFDVSNLESS
D
V
I
F
Y
IDD
N
L
E
-
T
F
I
-
K
P
F
----
A
K
----
D
K
K
E
----
L
---
V
Q
L
S
K
T
I
NLL---PARSHS
F
S
K
QI------THTQDEK---
D
L
H
I
W
LSPEN
A
K
S
M
I
L
S
I
S
E
A
L
S
NIDKENASRYNY
N
A
I
K
A
K
K
K
I
N
Q
E
A
E
K
I
A
K
E
L
N
D
F--KNQ
K
--
Y
I
V
T
H
D
A
Y
Q
Y
F
E
K
Y
FGLNH
P
S
V
I
L
S
IEEDSY
I
G
M
K
S
L
M
K
L
K
K
V
M
E
EEN
I
K
C
I
F
SHSLEDSIKPKVL-----SND-----A-----
K
------
M
I
-----
I
LDPI----GSNI----EP---G
K
D
A
Y
L
A
I
I
N
D
I
T
Q
N
F
K
S
C
FAGYQ
2
PsiBlast_PDB
94.79
25%
-79
- C2 -
2XY4
5
?
A:
[26-287]
-----------------------------------
L
L
P
D
G
A
S
E
H
D
Y
S
L
R
P
S
D
V
K
R
L
Q
G
A
D
L
V
V
W
V
G
P
E
M
E
-
A
F
M
-
E
K
S
----
V
R
NIP-
D
N
K
Q
VT--
I
---
A
Q
L
A
D
V
K
P
L
L
MKG------------------
H
H
H
G
E
Y
---
N
M
H
L
W
L
S
P
E
I
A
R
A
T
A
V
A
I
H
E
K
L
V
E
L
M
P
Q
S
R
A
K
L
D
A
N
L
K
D
F
E
A
Q
L
A
A
T
D
K
Q
V
G
N
E
L
A
P
L
--
K
G
K
G
--
Y
F
V
F
H
D
A
Y
G
Y
Y
E
K
H
Y
G
L
T
-
P
L
G
H
F
T
V
N
P
E
I
Q
P
G
A
Q
R
L
H
E
I
R
T
Q
L
V
E
Q
K
A
T
C
V
F
A
---
E
P
Q
F
R
P
A
V
V
E
A
V
A
R
G
T
S
-----
V
-----
R
------
M
G
-----
T
L
D
P
L
----
G
T
N
I
----
K
L
---
G
K
T
S
Y
S
A
F
L
S
Q
L
A
N
Q
Y
A
S
C
L
K
G
D
-
1
PsiBlast_PDB
94.40
25%
-85
- C2 -
2XQV
3
?
A:
[26-287]
-----------------------------------
L
L
P
D
G
A
S
E
H
D
Y
S
L
R
P
S
D
V
K
R
L
Q
G
A
D
L
V
V
W
V
G
P
E
M
E
-
A
F
M
-
E
K
S
----
V
R
NIP-
D
N
K
Q
VT--
I
---
A
Q
L
A
D
V
K
P
L
L
MKG-------------------
H
H
G
E
Y
---
N
M
H
L
W
L
S
P
E
I
A
R
A
T
A
V
A
I
H
E
K
L
V
E
L
M
P
Q
S
R
A
K
L
D
A
N
L
K
D
F
E
A
Q
L
A
A
T
D
K
Q
V
G
N
E
L
A
P
L
--
K
G
K
G
--
Y
F
V
F
H
D
A
Y
G
Y
Y
E
K
H
Y
G
L
T
-
P
L
G
H
F
T
V
N
P
E
I
Q
P
G
A
Q
R
L
H
E
I
R
T
Q
L
V
E
Q
K
A
T
C
V
F
A
---
E
P
Q
F
R
P
A
V
V
E
A
V
A
R
G
T
S
-----
V
-----
R
------
M
G
-----
T
L
D
P
L
----
G
T
N
I
----
K
L
---
G
K
T
S
Y
S
A
F
L
S
Q
L
A
N
Q
Y
A
S
C
L
K
G
--
3
PsiBlast_PDB
93.23
25%
-81
- C2 -
4BBP
5
?
A:
[27-288]
-----------------------------------
L
L
P
D
G
A
S
E
H
D
Y
S
L
R
P
S
D
V
K
R
L
Q
G
A
D
L
V
V
W
V
G
P
E
M
E
-
A
F
M
-
E
K
S
----
V
R
NIP-
D
N
K
Q
VT--
I
---
A
Q
L
A
D
V
K
P
L
L
MK-------------------
H
H
H
G
E
Y
---
N
M
H
L
W
L
S
P
E
I
A
R
A
T
A
V
A
I
H
E
K
L
V
E
L
M
P
Q
S
R
A
K
L
D
A
N
L
K
D
F
E
A
Q
L
A
A
T
D
K
Q
V
G
N
E
L
A
P
L
--
K
G
K
G
--
Y
F
V
F
H
D
A
Y
G
Y
Y
E
K
H
Y
G
L
T
-
P
L
G
H
F
T
V
N
P
E
I
Q
P
G
A
Q
R
L
H
E
I
R
T
Q
L
V
E
Q
K
A
T
C
V
F
A
---
E
P
Q
F
R
P
A
V
V
E
A
V
A
R
G
T
S
-----
V
-----
R
------
M
G
-----
T
L
D
P
L
----
G
T
N
I
----
K
L
---
G
K
T
S
Y
S
A
F
L
S
Q
L
A
N
Q
Y
A
S
C
L
K
G
D
-
4
PsiBlast_PDB
92.71
25%
-84
- C2 -
2XH8
4
?
A:
[52-290]
-----------------------------------
L
L
P
D
G
A
S
E
H
D
Y
S
L
R
P
S
D
V
K
R
L
Q
G
A
D
L
V
V
W
V
G
P
E
M
E
-
A
F
M
-
E
K
S
----
V
R
NIP-
D
N
K
Q
--------
V
T
I
A
Q
L
A
D
V
K
---
P
L
--------
L
------
M
K
G
A
G
E
Y
---
N
M
H
L
W
L
S
P
E
I
A
R
A
T
A
V
A
I
H
E
K
L
V
E
L
M
P
Q
S
R
A
K
L
D
A
N
L
K
D
F
E
A
Q
L
A
A
T
D
K
Q
V
G
N
E
L
A
P
L
--
K
G
K
G
--
Y
F
V
F
H
D
A
Y
G
Y
Y
E
K
H
Y
G
L
T
-
P
L
G
H
F
T
V
N
P
E
I
Q
P
G
A
Q
R
L
H
E
I
R
T
Q
L
V
E
Q
K
A
T
C
V
F
A
---
E
P
Q
F
R
P
A
V
V
E
A
V
A
R
G
T
S
-----
V
-----
R
------
M
G
-----
T
L
D
P
L
----
G
T
N
I
----
K
L
---
G
K
T
S
Y
S
A
F
L
S
Q
L
A
N
Q
Y
A
S
C
L
K
G
--
5
PsiBlast_PDB
91.27
26%
-76
- C2 -
2OSV
1
ZNUA_ECOLI
A:
[26-283]
-----------------------------------
L
L
P
D
G
A
S
E
H
D
Y
S
L
R
P
S
D
V
K
R
L
Q
N
A
D
L
V
V
W
V
G
P
E
M
E
-
A
F
M
Q
K
P
V
----
S
K
LPGA
K
Q
V
T
----
I
---
A
Q
L
E
D
V
K
P
L
L
---
M
K
S
-------------------
D
F
---
N
M
H
L
W
L
S
P
E
I
A
R
A
T
A
V
A
I
H
G
K
L
V
E
L
M
P
Q
S
R
A
K
L
D
A
N
L
K
D
F
E
A
Q
L
A
S
T
E
T
Q
V
G
N
E
L
A
P
L
--
K
G
K
G
--
Y
F
V
F
H
D
A
Y
G
Y
F
E
K
Q
F
G
L
T
-
P
L
G
H
F
T
V
N
P
E
I
Q
P
G
A
Q
R
L
H
E
I
R
T
Q
L
V
E
Q
K
A
T
C
V
F
A
---
E
P
Q
F
R
P
A
V
V
-----
E
S
V
-----
A
RGTS
V
R
------
M
G
-----
T
L
D
P
L
----
G
T
N
I
----
K
L
---
G
K
T
S
Y
S
E
F
L
S
Q
L
A
N
Q
Y
A
S
C
L
K
G
--
7
PsiBlast_PDB
91.04
26%
-76
- C2 -
2PS0
2
ZNUA_ECOLI
A:
[26-283]
-----------------------------------
L
L
P
D
G
A
S
E
H
D
Y
S
L
R
P
S
D
V
K
R
L
Q
N
A
D
L
V
V
W
V
G
P
E
M
E
-
A
F
M
Q
K
P
V
----
S
K
LPGA
K
Q
V
T
----
I
---
A
Q
L
E
D
V
K
P
L
L
---
M
K
S
------------------
G
D
F
---
N
M
H
L
W
L
S
P
E
I
A
R
A
T
A
V
A
I
H
G
K
L
V
E
L
M
P
Q
S
R
A
K
L
D
A
N
L
K
D
F
E
A
Q
L
A
S
T
E
T
Q
V
G
N
E
L
A
P
L
--
K
G
K
G
--
Y
F
V
F
H
D
A
Y
G
Y
F
E
K
Q
F
G
L
T
-
P
L
G
H
F
T
V
N
P
E
I
Q
P
G
A
Q
R
L
H
E
I
R
T
Q
L
V
E
Q
K
A
T
C
V
F
A
---
E
P
Q
F
R
P
A
V
V
-----
E
S
V
-----
A
RGTS
V
R
------
M
G
-----
T
L
D
P
L
----
G
T
N
I
----
K
L
---
G
K
T
S
Y
S
E
F
L
S
Q
L
A
N
Q
Y
A
S
C
L
K
G
D
-
8
PsiBlast_PDB
89.97
26%
-74
- C2 -
2PS3
-
ZNUA_ECOLI
A:
[52-309]
-----------------------------------
L
L
P
D
G
A
S
E
H
D
Y
S
L
R
P
S
D
V
K
R
L
Q
N
A
D
L
V
V
W
V
G
P
E
M
E
-
A
F
M
Q
K
P
V
----
S
K
LPGA
K
Q
V
T
----
I
---
A
Q
L
E
D
V
K
P
L
L
---
M
K
S
-----------------
H
G
D
F
---
N
M
H
L
W
L
S
P
E
I
A
R
A
T
A
V
A
I
H
G
K
L
V
E
L
M
P
Q
S
R
A
K
L
D
A
N
L
K
D
F
E
A
Q
L
A
S
T
E
T
Q
V
G
N
E
L
A
P
L
--
K
G
K
G
--
Y
F
V
F
H
D
A
Y
G
Y
F
E
K
Q
F
G
L
T
-
P
L
G
H
F
T
V
N
P
E
I
Q
P
G
A
Q
R
L
H
E
I
R
T
Q
L
V
E
Q
K
A
T
C
V
F
A
---
E
P
Q
F
R
P
A
V
V
-----
E
S
V
-----
A
RGTS
V
R
------
M
G
-----
T
L
D
P
L
----
G
T
N
I
----
K
L
---
G
K
T
S
Y
S
E
F
L
S
Q
L
A
N
Q
Y
A
S
C
L
K
G
D
-
9
PsiBlast_PDB
89.54
26%
-77
- C2 -
2PS9
1
ZNUA_ECOLI
A:
[26-283]
-----------------------------------
L
L
P
D
G
A
S
E
H
D
Y
S
L
R
P
S
D
V
K
R
L
Q
N
A
D
L
V
V
W
V
G
P
E
M
E
-
A
F
M
Q
K
P
V
----
S
K
LPGA
K
Q
V
T
----
I
---
A
Q
L
E
D
V
K
P
L
L
---
M
K
S
I
------------------
D
F
---
N
M
H
L
W
L
S
P
E
I
A
R
A
T
A
V
A
I
H
G
K
L
V
E
L
M
P
Q
S
R
A
K
L
D
A
N
L
K
D
F
E
A
Q
L
A
S
T
E
T
Q
V
G
N
E
L
A
P
L
--
K
G
K
G
--
Y
F
V
F
H
D
A
Y
G
Y
F
E
K
Q
F
G
L
T
-
P
L
G
H
F
T
V
N
P
E
I
Q
P
G
A
Q
R
L
H
E
I
R
T
Q
L
V
E
Q
K
A
T
C
V
F
A
---
E
P
Q
F
R
P
A
V
V
-----
E
S
V
-----
A
RGTS
V
R
------
M
G
-----
T
L
D
P
L
----
G
T
N
I
----
K
L
---
G
K
T
S
Y
S
E
F
L
S
Q
L
A
N
Q
Y
A
S
C
L
K
G
--
10
PsiBlast_PDB
89.46
26%
-71
- C2 -
2OGW
1
ZNUA_ECOLI
A:
[52-308]
-----------------------------------
L
L
P
D
G
A
S
E
H
D
Y
S
L
R
P
S
D
V
K
R
L
Q
N
A
D
L
V
V
W
V
G
P
E
M
E
-
A
F
M
Q
K
P
V
----
S
K
LPGA
K
Q
V
T
----
I
---
A
Q
L
E
D
V
K
P
L
L
---
M
K
--------------------
D
F
---
N
M
H
L
W
L
S
P
E
I
A
R
A
T
A
V
A
I
H
G
K
L
V
E
L
M
P
Q
S
R
A
K
L
D
A
N
L
K
D
F
E
A
Q
L
A
S
T
E
T
Q
V
G
N
E
L
A
P
L
--
K
G
K
G
--
Y
F
V
F
H
D
A
Y
G
Y
F
E
K
Q
F
G
L
T
-
P
L
G
H
F
T
V
N
P
E
I
Q
P
G
A
Q
R
L
H
E
I
R
T
Q
L
V
E
Q
K
A
T
C
V
F
A
---
E
P
Q
F
R
P
A
V
V
-----
E
S
V
-----
A
-----
R
------
G
T
S
V
R
M
G
T
L
D
P
L
----
G
T
N
I
----
K
L
---
G
K
T
S
Y
S
E
F
L
S
Q
L
A
N
Q
Y
A
S
C
L
K
---
6
PsiBlast_PDB
89.38
26%
-73
- C2 -
2PRS
3
ZNUA_ECOLI
A:
[26-283]
-----------------------------------
L
L
P
D
G
A
S
E
H
D
Y
S
L
R
P
S
D
V
K
R
L
Q
N
A
D
L
V
V
W
V
G
P
E
M
E
-
A
F
M
Q
K
P
V
----
S
K
LPGA
K
Q
V
T
----
I
---
A
Q
L
E
D
V
K
P
L
L
---
M
K
-------------------
G
D
F
---
N
M
H
L
W
L
S
P
E
I
A
R
A
T
A
V
A
I
H
G
K
L
V
E
L
M
P
Q
S
R
A
K
L
D
A
N
L
K
D
F
E
A
Q
L
A
S
T
E
T
Q
V
G
N
E
L
A
P
L
--
K
G
K
G
--
Y
F
V
F
H
D
A
Y
G
Y
F
E
K
Q
F
G
L
T
-
P
L
G
H
F
T
V
N
P
E
I
Q
P
G
A
Q
R
L
H
E
I
R
T
Q
L
V
E
Q
K
A
T
C
V
F
A
---
E
P
Q
F
R
P
A
V
V
-----
E
S
V
-----
A
RGTS
V
R
------
M
G
-----
T
L
D
P
L
----
G
T
N
I
----
K
L
---
G
K
T
S
Y
S
E
F
L
S
Q
L
A
N
Q
Y
A
S
C
L
K
G
D
-
23
HHSearch
85.74
24%
-76
- C2 -
2PRS
3
ZNUA_ECOLI
A:
[26-283]
-----------------------------------
L
L
P
D
G
A
S
E
H
D
Y
S
L
R
P
S
D
V
K
R
L
Q
N
A
D
L
V
V
W
V
G
P
E
M
E
-
A
F
M
-
Q
K
P
----
V
S
----
K
L
P
G
A---
K
QVT
I
A
Q
L
E
D
V
K
P
L
---
L
M
K
------------------
G
D
F
---
N
M
H
L
W
L
S
P
E
I
A
R
A
T
A
V
A
I
H
G
K
L
V
E
L
M
P
Q
S
R
A
K
L
D
A
N
L
K
D
F
E
A
Q
L
A
S
T
E
T
Q
V
G
N
E
L
A
P
L
--
K
G
K
G
--
Y
F
V
F
H
D
A
Y
G
Y
F
E
K
Q
F
G
L
T
P
L
G
H
F
T
V
N
-
P
E
I
Q
P
G
A
Q
R
L
H
E
I
R
T
Q
L
V
E
Q
K
A
T
C
V
F
A
E
P
Q
F
R
P
A
V
V
E
S
V
-----
A
R
G
TS---
V
-----
R
------
M
G
-----
T
L
D
P
L
----
G
T
N
I
----
K
L
---
G
K
T
S
Y
S
E
F
L
S
Q
L
A
N
Q
Y
A
S
C
L
K
G
D
-
26
HHSearch
85.61
22%
-78
- C2 -
2O1E
1
ZNUA_BACSU
A:
[48-302]
-----------------------------------
L
I
P
S
S
V
E
P
H
D
W
E
P
T
P
K
D
I
A
N
I
Q
D
A
D
L
F
V
Y
N
S
E
Y
M
E
-
T
W
V
-
P
S
A
----
E
K
----
S
M
G
Q
G---
H
A
V
F
V
N
A
S
K
G
I
D
L
M
---
E
G
-------------------
H
A
M
---
D
P
H
V
W
L
S
P
V
L
A
Q
K
E
V
K
N
I
T
A
Q
I
V
K
Q
D
P
D
N
K
E
Y
Y
E
K
N
S
K
E
Y
I
A
K
L
Q
D
L
D
K
L
Y
R
T
T
A
K
K
A
--
E
K
K
E
--
F
I
T
Q
H
T
A
F
G
Y
L
A
K
E
Y
G
L
K
Q
V
P
I
A
G
L
S
-
P
D
Q
E
P
S
A
A
S
L
A
K
L
K
T
Y
A
K
E
H
N
V
K
V
I
Y
F
E
E
I
A
S
S
K
V
A
D
T
L
-----
A
S
E
IG---
A
-----
K
------
T
E
-----
V
L
N
T
L
----
E
G
L
S
----
K
E
E
Q
D
K
G
L
G
Y
I
D
I
M
K
Q
N
L
D
A
L
K
D
S
L
L
V
--
16
PsiBlast_PDB
84.88
23%
-75
- C2 -
2O1E
1
ZNUA_BACSU
A:
[48-293]
-----------------------------------
L
I
P
S
S
V
E
P
H
D
W
E
P
T
P
K
D
I
A
N
I
Q
D
A
D
L
F
V
Y
N
S
E
Y
M
E
-
T
W
V
-
P
S
A
----
E
K
----
S
M
G
Q
G
H
A
V
F
---
V
N
A
S
K
G
I
D
L
M
---
E
G
----------------------HAM
D
P
H
V
W
L
S
P
V
L
A
Q
K
E
V
K
N
I
T
A
Q
I
V
K
Q
D
P
D
N
K
E
Y
Y
E
K
N
S
K
E
Y
I
A
K
L
-
Q
D
L
D
K
L
Y
R
T
T
A
K
K
--
A
E
K
K
E
-
F
I
T
Q
H
T
A
F
G
Y
L
A
K
E
Y
G
L
K
Q
-
V
P
I
A
G
L
S
P
D
Q
E
P
S
A
A
S
L
A
K
L
K
T
Y
A
K
E
H
N
V
K
V
I
Y
F
E
E
I
A
S
S
K
V
A
D
T
L
-----
A
S
E
IG---
A
-----
K
------
T
E
-----
V
L
N
T
L
----
E
G
L
S
----
K
E
---
E
Q
D
K
G
L
G
Y
I
D
I
M
K
Q
N
L
D
A
L
K
D
S
L
L
20
PsiBlast_PDB
80.97
24%
-75
- C2 -
3HJT
1
?
A:
[55-261]
---------------------------------------------------
D
V
A
A
I
Y
D
A
D
L
F
V
Y
H
S
H
T
L
E
-
A
W
A
-
R
D
L
DP---
K
----
S
K
V
N
----
V
---
F
E
A
S
K
P
L
T
L
D
---
R
V
K
G
--------------------TLY
D
P
H
T
W
T
D
P
V
L
A
G
E
E
A
V
N
I
A
K
E
L
G
H
L
D
P
K
H
K
D
S
Y
T
K
K
A
K
A
F
K
K
E
A
E
Q
L
T
E
E
Y
T
Q
K
F
K
K
V
--
R
S
K
T
--
F
V
T
Q
H
T
A
F
S
Y
L
A
K
R
F
G
L
K
Q
L
G
-
I
S
G
I
S
P
E
Q
E
P
S
P
R
Q
L
K
E
I
Q
D
F
V
K
E
Y
N
V
K
T
I
F
A
---
E
D
N
V
N
P
K
I
A
H
A
I
A
K
S
T
G
-----
A
-----
K
------
V
K
-----
T
L
S
P
L
----
E
A
A
P
----
S
G
---
N
K
T
Y
L
E
N
L
R
A
N
L
E
V
L
Y
Q
Q
L
K
----
24
HHSearch
80.55
20%
-64
- C2 -
3CX3
3
?
A:
[36-283]
-----------------------------------
M
I
Q
S
S
S
G
I
H
S
F
E
P
S
A
N
D
I
A
A
I
Y
D
A
D
V
F
V
Y
H
S
H
T
L
E
-
S
W
A
-
G
S
L
----
D
P
----
N
L
K
K
SKV-
K
V--
L
E
A
S
E
G
M
T
L
E
---
R
V
P
G
-----------------
T
L
Y
---
D
P
H
T
W
L
D
P
E
K
A
G
E
E
A
Q
I
I
A
D
K
L
S
E
V
D
S
E
H
K
E
T
Y
Q
K
N
A
Q
A
F
I
K
K
A
Q
E
L
T
K
K
F
Q
P
K
F
E
K
A
--
T
Q
K
T
--
F
V
T
Q
H
T
A
F
S
Y
L
A
K
R
F
G
L
N
Q
L
G
I
A
G
I
S
-
P
E
Q
E
P
S
P
R
Q
L
T
E
I
Q
E
F
V
K
T
Y
K
V
K
T
I
F
T
E
S
N
A
S
S
K
V
A
E
T
L
-----
V
K
S
T
G
---
V
-----
G
------
L
K
-----
T
L
N
P
L
----
E
S
D
P
----
Q
----
N
D
K
T
Y
L
E
N
L
E
E
N
M
S
I
L
A
E
E
L
----
39
Fugue
80.35
21%
-58
- C2 -
1PSZ
1
MTSA_STRPN
A:
[18-303]
KKDTTSGQK
L
K
V
V
A
TN
S
I
I
A
D
I
T
K
N
I
AGDKID
L
H
S
I
V
P
I
G
Q
D
P
H
E
Y
E
P
L
P
E
D
V
K
K
T
S
E
A
D
L
I
F
Y
N
G
I
N
L
E
-
T
G
G
-
N
A
W
----
F
T
----
K
L
V
E
----
N
---
A
K
K
T
E
N
K
-
D
Y
---
F
A
V
S
D
G
V
D
---VIYLEG
Q
N
E
K
G
K
E
---
D
P
H
A
W
L
N
L
E
N
G
I
I
F
A
K
N
I
A
K
Q
L
S
A
K
D
P
N
N
K
E
F
Y
E
K
N
L
K
E
Y
T
D
K
L
D
K
L
D
K
E
S
K
D
K
F
N
K
I
--
P
A
E
K
K
L
I
V
T
S
E
G
A
F
K
Y
F
S
K
A
Y
G
V
P
S
A
Y
I
W
-
E
I
N
T
E
E
E
G
T
P
E
Q
I
K
T
L
V
E
K
L
R
Q
T
K
V
P
S
L
F
V
E
S
S
V
D
D
R
P
M
K
T
V
-----
S
Q
D
-----
T
------NIPIY
A
Q
I
-----
F
T
D
S
I
----
A
E
Q
G
----
K
E
---
G
D
S
-
Y
Y
S
M
M
K
Y
N
L
D
K
I
A
E
G
L
A
K
--
25
HHSearch
79.62
19%
-58
- C2 -
3UJP
7
?
A:
[58-301]
-----------------------------------
I
T
R
I
G
A
E
I
H
G
Y
E
P
T
P
S
D
I
V
K
A
Q
D
A
D
L
I
L
Y
N
G
M
N
L
E
-
R
W
F
-
E
Q
F
----
L
G
----
N
V
K
D
V
---
P
S
--
V
V
L
T
E
G
I
E
P
I
---
P
I
A
D
-------------
G
P
Y
T
D
K
P
---
N
P
H
A
W
M
S
P
R
N
A
L
V
Y
V
E
N
I
R
Q
A
F
V
E
L
D
P
D
N
A
K
Y
Y
N
A
N
A
A
V
Y
S
E
Q
L
K
A
I
D
R
Q
L
G
A
D
L
E
Q
V
PA
N
Q
R
F
--
L
V
S
C
E
G
A
F
S
Y
L
A
R
D
Y
G
M
E
E
I
Y
M
W
P
I
N
-
A
E
Q
Q
F
T
P
K
Q
V
Q
T
V
I
E
E
V
K
T
N
N
V
P
T
I
F
C
E
S
T
V
S
D
K
G
Q
K
Q
V
-----
A
Q
A
T
G---
A
-----
R
------
F
G
G
N
L
--
Y
V
D
S
L
----
S
T
E
E
-----
G
---
P
V
P
T
F
L
D
L
L
E
Y
D
A
R
V
I
T
N
G
L
L
A
--
27
HHSearch
78.60
18%
-77
- C2 -
1PQ4
1
?
A:
[29-289]
-----------------------------------
L
V
P
G
N
N
D
P
H
T
Y
E
P
K
P
Q
Q
L
A
A
L
S
E
A
E
A
Y
V
L
I
G
L
G
F
E
Q
P
W
L
-
E
K
L
----
K
A
----
A
N
A
N
M
---
K
L
--
I
D
S
A
Q
G
I
T
P
L
---
E
M
E
K
-----------------
M
V
A
---
D
P
H
I
W
L
S
P
T
L
V
K
R
Q
A
T
T
I
A
K
E
L
A
E
L
D
P
D
N
R
D
Q
Y
E
A
N
L
A
A
F
L
A
E
L
E
R
L
N
Q
E
L
G
Q
I
L
Q
P
L
--
P
Q
R
K
--
F
I
V
F
H
P
S
W
A
Y
F
A
R
D
Y
N
L
V
Q
I
P
I
E
--
V
-
E
G
Q
E
P
S
A
Q
E
L
K
Q
L
I
D
T
A
K
E
N
N
L
T
M
V
F
G
E
T
Q
F
S
T
K
S
S
E
A
I
-----
A
A
E
I
G---
A
-----
G
------
V
E
-----
L
L
D
P
L
----
A
--------------
A
D
W
S
S
N
L
K
A
V
A
Q
K
I
A
N
A
N
S
---
30
HHSearch
76.94
19%
-42
- C2 -
3MFQ
1
?
A:
[33-282]
-----------------------------------
L
I
P
A
G
E
D
P
H
L
Y
V
A
K
S
S
D
L
S
K
L
Q
K
A
D
L
V
L
Y
H
G
L
H
F
E
-
G
K
M
-
V
E
A
----
L
E
----
K
T
G
---------
V
A
V
S
K
N
F
N
A
K
---
D
L
N
T
M
-----
D
------
E
D
G
E
E
I
V
---
D
P
H
F
W
F
S
I
P
L
Y
K
S
A
V
A
V
A
S
E
E
L
Q
K
L
L
P
A
K
A
E
M
I
Q
K
N
T
E
K
Y
Q
A
Q
L
D
D
L
H
A
W
V
E
K
E
L
S
V
I
PK
E
S
R
Y
--
L
V
T
P
H
D
A
F
N
Y
F
A
A
S
Y
D
F
T
L
Y
A
P
Q
G
V
S
-
T
D
S
E
V
A
N
S
D
M
I
E
T
V
N
L
I
I
D
H
N
I
K
A
I
F
T
E
S
T
T
N
P
E
R
M
K
K
L
-----
Q
E
A
V
K
A
K
G
G
-----
Q
------
V
E
-----
V
V
T
G
E
GK
E
L
F
S
D
S
LAPE
G
E
---
E
G
D
T
F
I
D
M
Y
K
H
N
V
K
L
M
V
K
Y
L
K
---
11
PsiBlast_PDB
76.60
24%
-76
- C2 -
3GI1
1
?
A:
[54-260]
---------------------------------------------------
D
V
A
A
I
Y
D
A
D
L
F
V
Y
H
S
H
T
L
E
-
A
W
A
-
R
D
L
DPNL
K
K
----
S
K
V
D
----
V
---
F
E
A
S
K
P
L
T
L
D
---
R
V
K
---------------------LY-
D
P
H
T
W
T
D
P
V
L
A
G
E
E
A
V
N
I
A
K
E
L
G
R
L
D
P
K
H
K
D
S
Y
T
K
N
A
K
A
F
K
K
E
A
E
Q
L
T
E
E
Y
T
Q
K
F
K
K
V
--
R
S
K
T
--
F
V
T
Q
H
T
A
F
S
Y
L
A
K
R
F
G
L
K
Q
L
G
-
I
S
G
I
S
P
---
P
S
P
R
Q
L
K
E
I
Q
D
F
V
K
E
Y
N
V
K
T
I
F
A
---
E
D
N
V
N
P
K
I
A
H
A
I
A
K
S
T
G
-----
A
-----
K
------
V
K
-----
T
L
S
P
L
----
E
A
A
P
----
S
G
---
N
K
T
Y
L
E
N
L
R
A
N
L
E
V
L
Y
Q
Q
L
K
----