@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0139: (2016-03-12 )
MKKIYKSLTVSAIVATVSLSALPQSLAITHESQPTKQQRTVLFDRSHGQTAGAADWVSDGAFSDYADSIQKQGYDVKAIDGHSNITEASLKSSKIFVIPEANIPFKESEQAAIVNYVKQGGNVVFISDHYNADRNLNRIDSSEAMNGYRRGAYEDMSKGMNAEEKSSTAMQGVKSSDWLSTNFGVRFRYNALGDLNTSNIVSSKESFGITEGVKSVSMHAGSTLAITNPEKAKGIVYTPEQLPAKSKWSHAVDQGIYNGGGKAEGPYVAISKVGKGKAAFIGDSSLVEDSSPKYVREDNGEKKKTYDGFKEQDNGKLLNNITAWMSKDSDGKSLKASGLTLDTKTKLLDFERPERSTEPEKEPWSQPPSGYKWYDPTTFKAGSYGSEKGADPQPNTPDDHTPPNQNVKISFDIPQNVSVNEPFEVTIHLKGFEANQTLENLRVGIYKEGGRQIGQFSSKDNDYNPPGYSTLPTVKADENGNATIKINAKVLESMEGSKIRLKLGDKTLITTDFK
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.....-....10-----.......--------------------.20...-----.....30---------------.........---------40...--------------...---..50--.-----.......60......---.-..70.....--------....----80-------..---------------.--------------.------------.-...--90........100-.-------------.-------------.--.------.-----.---------------.110.......120....----...130.......140-.-----.....-------..150.....-..160...--------------.-...170....-----...180--........190-.....-..-.------200..-....---.210......-.-220....-...230-------...-..-....240.......-------------250......-.260.......270....---....280-........290.-...-....300.......310.......320.-.....-------..330-..-...-----------..340...----....350.......360..----...-------------..370-..--.....380.-...----------------------------------------...390--.......400....-----.-..410...----....420.......430.......440.......450.-.......460.......470.......480........490......---.500------------.......510..-----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
K
K
I
Y
-
K
S
L
T
V
S
-----
A
I
V
A
T
V
S
--------------------
L
S
ALP
Q
-----
S
L
A
ITH----------------ESQPTKQ
Q
R
---------
T
V
L
F
D--------------RSH---GQTA--G-----AADWVSDG-A
F
S
D
Y
A
---
D
-
S
I
Q
-KQGY
D
--------
V
K
A
I----DG-------HS---------------N--------------I------------
T
-
E
AS--LKS
S
K
I
F
V
I
PEAN-I-------------P-------------F--K------E-----S---------------
E
Q
A
A
I
V
N
Y
V
K
QGG
N
V
V
F
I----SDHYNADRNLNRID-
S
-
S
-----
E
A
M
N
G
-------
Y
RRG
A
Y
E
D
M
S
-KGM
N
A
E
E
K
--------------
S
-
S
T
A
MQGVKSS-----DWLST---NF
G
V
R
F
R
Y
N-A-LGDL
N
-
T
S
-
N
------IVSS
K
-
E
SFG---
I
T
E
G
V
K
S
V
SM-H-AG
S
T
L
A
I-TNPE---------KAK-
G
I
-
V
YTPEQLPAK
S
K
W
S
-------------
H
A
V
D
Q
GIYN-GGGKAEG
P
Y
V
A
I
-
S
KVGK---G
K
A
A
FI--GDSSLVEDSS-P-KYV-REDNGEKKKTYDGFKEQDNG
K
L
L
N
N
I
-
T
-
A
W
MSK-------DSDGK-SL-KAS-----------
G
L
T
LDTKT----KLLDFERPERSTEPEKEPW----SQP-------------PSGYK-WY--DPTTFKAGS-YGS----------------------------------------EKGADP--QPNTPDDHTPPNQ
N
-----
V
-
K
I
S
F
DIPQ----NVSVNE
P
F
E
V
T
I
H
L
KGFEAN
Q
T
L
E
N
L
R
V
G
I
Y
KEGG-RQ-IGQFSSKDNDYNPPGYSTLP
T
V
KADENG-
N
A
T
I
K
I
N
A
K
V
L
E
SMEG
S
K
---
I
R
L
K
------------LG
D
K
T
L
I
TTDFK-----
28
Fugue
74.50
19%
30
- C2 -
4C3X
9
?
A:
[23-530]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-
W
T
S
E
C
D
-----
V
L
V
V
G
S
G
--------------------
G
G
A
L
T
G
-----
A
Y
T
A
A
A
----------------
Q
G
L
T
--------------
T
I
V
L
E
--------------
K
T
D
RFG
G
T
S
A
YS
G
-----
A
S
I
W
L
P
G
T
-
Q
V
Q
E
R
A
GLP
D
-
S
T
E
-
N
A
R
T
Y
--------
L
R
A
L
LG--
D
A
-------
E
S
---------------
E
--------------
R
------------
Q
-
D
A
Y
--
V
E
T
A
P
A
V
V
A
L
L
E
Q
-
N
-------------
P
-------------
N
--
I
------
E
-----
F
---------------
E
F
R
A
F
P
D
Y
Y
K
A
E
G
-----------
R
M
D
T
G
R
S
I
N
P
L
D
L
D
-
P
-----
A
D
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G
D
-------
L
A
G
K
V
R
P
E
L
D
-
Q
D
R
T
G
Q
D
H
--------------
A
-
P
G
P
M
I
G
G
R
A
L
I
G
R
L
L
A
A
V
Q
S
---
T
G
K
A
E
L
R
T
E
S
V
-
L
T
S
L
I
-
V
E
-
D
GRVV
G
A
E
V
E
S
G
-
G
E
T
Q
---
R
I
K
A
N
R
G
V
L
M
-
A
-
A
G
G
I
E
G
N
-
A
E
M
R
---------
E
Q
A
-
G
T
--------
P
G
K
A
I
W
S
MGPFGANTG----
D
A
I
S
A
G
I
A
V
-
G
G
A
T
A
L
L
D
Q
A
W
F
-
C
P
G
V
E
QPD
G
S
A
A
F
M
VG
V
R
G
G
L
V
V
D
S
A
G
E
-
R
Y
L
-
N
E
-----------------
S
L
P
Y
D
Q
F
-
G
-
R
A
M
D
A
-------
H
D
D
N
G
-
S
A
-
V
P
S
-----------
F
M
I
F
D
S
R
E
GGGL
P
A
I
C
I
P
N
T
A
P
A
K
H
L
E
A
G
T
W
----
V
G
A
-------------
D
T
L
E
E
-
L
A
--
A
K
T
G
L
P
A
D
A
-
L
R
S
T
V
--------------------------------------
E
K
F
N
D
A
--
A
K
L
G
V
D
E
E
F
H
R
G
E
D
-----
P
-
Y
D
A
F
F
C
P
P
----
N
G
G
A
N
A
A
L
T
A
I
E
N
G
P
F
Y
A
A
R
I
V
L
S
D
L
--------
G
-
T
K
-
G
G
L
V
T
D
V
N
G
R
V
L
R
A
D
G
S
A
I
D
G
L
Y
A
A
G
N
T
-
S
A
----------
S
L
S
G
R
F
YPG
P
G
V
P
------------
L
G
T
A
M
V
F
S
Y
R
A
A
Q
D
M
A
K
33
Fugue
68.13
13%
26
* C5 *
1QNI
6
?
A:
[10-581]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHVAPG
E
L
D
E
Y
-
Y
G
F
W
S
G
-----
G
H
Q
G
E
V
R
--------------------
V
L
G
V
P
S
-----
M
R
E
L
M
R
I
P
V
FNVDSATGWGIT
N
E
S
K
E
I
L
G
G
D
QQYL
N
G
D
C
H
H
P
H
I
S
--------------
M
T
D
---
G
R
Y
D
--
G
-----
K
Y
L
F
I
N
D
K
-
A
-
N
T
R
V
---
A
-
R
I
R
-
L
D
I
M
K
--------
T
D
K
I
----
T
H
I
P
NVQAI
H
G
---------------
L
--------------
R
------------
L
-
Q
K
V
--
P
K
T
N
Y
V
F
C
N
A
E
F
V
-
I
-------------
P
-------------
Q
--
P
------
N
DGTDF
S
---------------
L
D
N
S
Y
T
M
F
T
A
I
D
A
E
T
M
D
V
----
A
W
Q
V
I
V
D
G
N
L
D
N
T
D
-
A
-
D
YTGK
Y
A
T
S
T
C
-------
Y
N
S
E
R
A
V
D
L
A
-
G
T
M
R
N
D
R
D
--------------
W
-
V
V
V
F
N
V
E
R
I
A
-----
A
A
V
K
A
---
G
N
F
K
T
I
G
D
S
-
K
-
V
P
V
V
D
-
G
R
-
G
------
E
S
E
F
T
-
R
Y
I
P
---
V
P
K
N
P
H
G
L
N
T
S
P
-
D
G
K
Y
F
I
A
-
N
G
K
L
---------
S
P
T
-
V
S
-
V
I
A
I
D
K
L
D
D
L
F
E
D
K
-------------
I
E
L
R
D
T
I
V
A
-
E
P
E
L
G
L
G
P
L
H
T
T
F
D
G
R
G
N
---
A
Y
T
T
L
F
--
I
D
S
Q
V
C
K
W
N
I
-
A
-
D
A
I
-
K
H
Y
N
G
D
R
V
N
Y
I
R
Q
K
L
D
V
Q
Y
Q
P
G
H
N
H
A
-
S
-
L
T
E
S
R
-------
D
A
D
G
K
-
W
L
-
V
V
L
S
KFSKDRFLPV
G
P
L
H
P
E
N
D
----
Q
L
I
D
I
S
G
E
E
M
K
L
V
H
D
G
P
T
Y
----
A
E
P
H
D
C
I
L
V
R
RDQ
I
K
T
K
K
I
Y
E
-
R
N
--
D
P
Y
F
A
S
C
R
A
-
Q
A
E
----------------------------------------
K
D
G
V
T
L
--
E
S
D
N
K
V
I
R
D
G
N
K
V
R
-----
V
-
Y
M
T
S
V
A
P
Q
YGMT
D
F
K
V
K
E
G
D
E
V
T
V
Y
I
T
N
L
D
M
V
---
E
D
V
T
H
G
F
C
M
V
N
H
-
G
V
-
S
M
E
I
S
--------
P
Q
Q
T
A
S
V
T
F
T
A
G
K
P
G
-
V
Y
W
Y
Y
C
N
W
F
C
------
H
A
---
L
H
M
E
------------
M
V
G
R
M
L
V
E
A
A
-------
35
Fugue
65.70
18%
25
- C5 -
4C2E
-
CTPB_BACSU
A:
[2-436]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
-----
S
E
R
D
K
A
M
--------------------
D
K
I
E
K
A
-----
Y
E
L
I
S
N
----------------
E
Y
V
E
K
V
D
R
E
---------
K
L
L
E
G
--------------
A
I
Q
---
G
M
L
S
--
T
-----
L
N
D
------
P
Y
S
V
Y
M
---
D
-
K
Q
T
-
A
K
Q
F
S
--------
D
S
L
D
----
S
S
-------
F
E
---------------
G
--------------
I
G-----------
A
-
E
V
G
--
M
E
D
G
K
I
I
I
V
-----
S
-------------
P
-------------
F
--
K
------
K
-----
S
-----------------
P
A
E
K
A
G
L
K
P
N
D
E
I
I
S
I
----
N
G
---------------------
E
S
M
A
G
-------
K
D
---
L
N
H
A
V
-
L
K
I
R
G
K
K
G
--------------
S
-
S
V
S
M
K
I
Q
R
P
G
-----
T
K
K
Q
L
---
S
F
R
I
K
R
A
E
I
-
P
-
L
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T
V
F
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A
S
-
E
------
K
K
V
Q
G
-
H
S
V
G
Y
I
A
I
S
T
F
S
E
H
T
T
E
-
D
-
F
A
K
A
L
R
E
-
L
E
K
K
---------
E
I
E
-
G
L
-
V
I
D
V
R
G
N
P
------------------------------
G
G
Y
I
Q
S
V
E
E
I
L
-
K
H
------------------
F
V
T
K
D
Q
-
P
Y
I
Q
I
-
A
E
R
N
G
D
K
K
R
Y
F
S
T
L
T
H
K
K
A
Y
P
-
V
N
V
I
-
T
-
D
K
G
S
---------
A
A
A
S
-
E
I
-
L
A
G
-----------
A
L
K
E
A
G
H
Y
----
D
V
V
G
D
T
S
F
G
K
G
T
V
Q
Q
A
V
P
M
GDG
S
N
I
K
-------------
L
T
L
Y
K
-
W
L
--
T
P
N
----
G
N
-
W
I
H
----------------------------------------
K
K
G
I
E
P
T
I
A
I
K
Q
P
D
Y
F
S
A
G
P
L
Q
-----
L
-
K
E
P
L
K
V
D
M
----
N
N
E
D
V
K
H
A
Q
V
L
L
K
G
L
S
F
D
P
G
R
-----
E
D
G
Y
F
S
K
D
M
-
K
K
-
A
V
M
A
F
Q
D
Q
N
K
L
N
K
T
G
I
-------
I
D
T
R
T
-
A
E
T
L
N
Q
Q
I
E
K
K
K
S
D
E
K
N
D
---
L
Q
L
Q
------------
T
A
L
K
S
L
F
----------
11
HHSearch
59.28
10%
-37
- C6 -
2ISS
-
PDXT_THEMA
D:
[20-103]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
---------
K
I
G
V
L
--------------
G
V
Q
---
G
D
--------------------
V
R
E
H
V
---
E
-
A
L
H
-
K
L
G
V
E
--------
T
L
I
V
----
K
L
-------
P
-----------------------------------------------
E
Q
--
L
D
M
V
D
G
L
I
L
P
G
G
E
-
S
T
------------
T
-------------
M
--
I
R
I
L
K
E
-
M
-----
D
---------------
M
D
E
K
L
V
E
R
I
N
N
G
L
P
V
F
A
T
----
C
A
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
58.49
19%
5
- C4 -
4Q2C
3
?
A:
[24-949]
G
S
P
V
G
A
A
G
W
R
VDPWIFWA
K
W
G
S
G
PDL
G
W
H
P
L
L
C
H
M
L
D
V
A
A
V
T
L
Q
M
W
R
RVLP
A
A
W
K
A
R
I
S
G
V
L
GVG
Q
E
D
A
E
R
W
L
A
F
F
A
G
G
H
DIGKAS
P
A
F
Q
L
QLRPEQG
R
E
L
V
A
R
R
L
R
D
A
G
L
P
L
F
N
A
R
A
P
H
G
T
I
S
A
N
V
L
E
T
VLADVFGLS
G
R
S
A
R
W
V
A
F
A
V
G
G
HHGFVPSYDEVRRDLDQQAVGW
G
M
W
D
A
A
R
E
V
L
L
C
R
L
A
D
A
L
GLPG
S
S
R
P
T
VES
T
P
D
A
F
M
L
A
G
L
V
S
V
A
D
W
I
G
S
NEEYFPYAAQSALQVPQLD
A
E
A
Y
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A
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R
A
M
A
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L
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T
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Y
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L
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F
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-----
L
L
E
W
L
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A
--------------------
L
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--------
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V
V
L
S
----------------
A
T
L
P
S
A
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---------
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L
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--------------
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---
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A
G
W
--
Q
-----
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---
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---
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--------
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I
----
H
-----------------------------------------------------
F
-
A
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--
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A
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R
W
V
S
-
A
-------------
P
-------------
E
--
H
------
E
-----
A
---------------
L
G
Q
L
L
A
E
A
L
S
Q
G
G
C
A
A
I
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C
NT
V
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R
A
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A
L
Y
S
A
L
R
E
V
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-
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-----
L
A
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G
MPE
L
D
L
L
H
A
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Y
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Y
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R
E
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R
E
A
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T
L
G
R
--------------
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-
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R
A
-----
I
L
V
A
T
QVI
E
Q
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L
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L
D
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D
-
L
M
V
T
D
L
A
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P
V
-
D
------
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V
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-
V
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V
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I
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-
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S
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V
Y
D
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E
H
T
L
L
R
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A
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RDRDTLQL
P
E
D
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E
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L
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E
Q
V
Y
S
-
D
G
R
V
P
Q
G
A
--------------
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R
--
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L
W
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F
K
A
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Q
-
K
V
L
-
R
E
D
S
L
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A
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Y
R
Y
--
I
K
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P
G
Y
N
S
I
W
G
I
V
-
T
-
A
S
V
E
E
-------
D
A
P
E
L
-
H
P
-
A
L
Q
-----------
A
L
T
------------------
R
L
A
E
P
S
-------------------------------
V
--
S
A
V
C
L
V
A
G
S
-
G
G
P
-------------------------------------------
C
L
P
--
D
G
T
P
V
D
L
D
T
P
P
D
A
A
M
A
E
R
L
L
-
R
R
S
V
A
I
-
T
----
D
A
R
V
L
D
P
L
L
D
V
P
V
P
K
G
W
E
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S
L
L
R
G
Y
R
P
L
V
F
D
A
S
G
-
R
A
M
V
G
R
W
---------------------------
I
V
R
I
D
P
E
----------------------------
L
G
----
I
V
V
E
S
P
-----
30
Fugue
55.44
10%
22
- C8 -
3MOI
-
?
A:
[1-387]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
-----
I
R
F
G
I
C
G
--------------------
L
G
F
A
G
S
-----
V
L
M
A
P
A
----------------
M
R
H
H
P
D
A
Q
I
---------
V
A
A
C
D
--------------
P
N
E
---
D
V
R
E
--
R
-----
F
G
K
E
Y
G
I
P
-
V
F
A
T
L
A
---
E
-
M
M
Q
-
H
V
Q
M
D
--------
A
V
Y
I
ASPH
Q
F
-------
H
C
---------------
E
--------------
H
------------
V
-
V
Q
A
--
S
E
Q
G
L
H
I
I
V
-
E
K
P
-
L
-------------
T
-------------
L
--
S
------
R
-----
D
---------------
E
A
D
R
M
I
E
A
V
E
R
A
G
V
H
L
V
V
----
G
T
S
R
S
H
D
P
V
V
R
T
L
R
-
A
-
I
-----
V
Q
E
G
----------------------------------------------------------------------------
S
-
V
G
R
V
S
-
M
L
-
N
------
C
F
N
Y
T
-
D
F
L
Y
---
R
P
R
R
P
E
E
L
D
T
-
S
-
K
G
G
G
I
I
Y
-
N
Q
------------------------------
L
P
-------------
H
Q
I
D
S
I
K
T
I
-
T
G
Q
R
I
T
A
V
R
A
M
T
-
G
R
L
D
P
---
K
R
P
T
----------
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G
N
C
-
A
-
A
M
L
-
T
L
E
D
G
A
------------
C
A
V
M
V
Y
S
G
-
Y
-
D
H
F
D
S
-------
D
E
M
H
F
-
W
L
-
A
E
G
-----------
G
R
A
K
Q
P
N
H
----
G
G
A
R
K
V
L
R
Q
L
E
G
D
E
A
E
L
R
R
----
S
R
Y
-------------
G
F
G
------------------
G
P
----------------------------------------
I
S
K
S
D
R
--
K
Q
P
H
F
G
V
M
L
V
T
C
E
H
-----
A
-
D
L
R
A
S
---------------
P
E
G
V
L
V
Y
G
D
E
G
V
R
E
V
P
A
I
T
G
R
G
P
F
S
Q
G
-
D
T
-
I
D
E
L
R
D
A
I
A
G
V
A
P
A
L
R
D
-------
A
R
W
G
-
K
D
T
L
E
V
C
L
A
V
L
E
S
S
A
T
G
R
---
Q
V
E
R
-----------------------------
27
Fugue
54.64
13%
22
* C8 *
3DTY
1
?
A:
[7-398]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
I
P
-
Q
P
I
R
W
A
M
----
V
G
G
G
S
Q
S
--------------------
Q
I
G
Y
I
H
-----
R
C
A
A
L
R
----------------
D
N
T
F
V
L
V
A
G
---------
A
F
D
I
D
--------------
P
I
R
---
G
S
A
F
--
G
-----
E
Q
L
G
V
D
S
E
R
C
Y
A
D
Y
L
---
S
M
F
E
Q
-
E
A
R
R
A
DGIQ
A
V
S
I
A
T
P
N
----
G
T
-------
H
Y
---------------
S
--------------
I
------------
T
-
K
A
A
--
L
E
A
G
L
-
H
V
V
C
E
K
P
-
L
-------------
C
-------------
F
--
T
------
V
-----
E
---------------
Q
A
E
N
L
R
E
L
S
H
K
H
N
R
I
V
G
V
----
T
Y
G
Y
A
G
H
Q
L
I
E
Q
A
R
-
E
M
I
-----
A
A
----------------------------------------------------------------------------
G
-
E
-
L
G
D
V
R
M
V
H
M
Q
------
F
A
H
G
F
-
H
S
A
G
---
P
S
Y
V
L
G
D
V
G
T
-
H
-
P
L
Y
L
S
E
V
M
L
P
D
L
---------
K
I
K
-
R
L
M
C
S
R
Q
S
F
V
A
S
R
A
P
------------------------------------------------------------
L
E
D
N
-
A
-
Y
T
L
M
E
Y
E
G
G
A
--------------------
M
G
M
V
W
S
S
A
-------
V
N
A
G
S
M
H
G
-
Q
K
I
-----------
R
V
I
G
S
R
A
S
----
L
E
W
W
D
E
R
P
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Q
L
S
F
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V
Q
G
--------------------------------
Q
P
A
Q
I
L
E
R
G
M
G
Y
L
----------------------------------------
H
P
N
A
L
I
--
D
D
R
I
G
G
G
H
--------------------------------------------
P
E
G
L
F
E
A
W
A
N
L
Y
Y
R
F
A
-
L
A
M
D
A
T
D
R
S
D
T
Q
A
L
S
A
V
R
Y
P
G
------
I
D
A
G
-
V
E
G
V
R
W
V
E
R
C
V
L
S
A
D
N
D
S
---
I
W
V
A
------------
Y
E
G
H
H
H
H
H
H
--------
19
HHSearch
54.30
18%
-32
- C6 -
3OT1
-
?
A:
[9-111]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
---------
R
I
L
V
P
--------------
V
A
H
---
G
S
E
E
---------------
M
-
E
T
V
I
I
V
---
D
-
T
L
V
-
R
A
G
F
Q
--------
V
T
M
A
----
A
V
-------
G
D
KL-------------
Q
V
Q
G
SRG
V
W
L
T
A
EQT
L
------------
E
-
A
C
S
--
A
E
A
F
D
A
L
A
L
P
G
G
V
-
G
G
A
Q
----------
A
-------------
F
A
D
S
------
T
-----
A
---------------
L
L
A
L
I
D
A
F
S
Q
Q
G
K
L
V
A
A
I
----
C
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
54.09
17%
-48
- C6 -
3L18
-
?
A:
[-1-101]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
---------
K
V
L
F
L
--------------
S
A
D
---
G
F
E
D
---------------
L
-
E
L
I
Y
P
L
---
H
-
R
I
K
-
E
E
G
H
E
--------
V
Y
V
A
----
S
F
-------
Q
R
G
K
I
T
G
KHG
Y
S
V
N
V
DL
T
--------------
F
------------
E
-
E
V
D
--
P
D
E
F
D
A
L
V
L
P
G
G
K
-
A
-------------
P
E
I
-----------
V
R
L
N
------
E
-----
K
---------------
A
V
M
I
T
R
R
M
F
E
D
D
K
P
V
A
S
I
----
C
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
52.77
15%
-43
- C6 -
3L4E
1
Y363_LISMO
A:
[26-124]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
K
---------
T
V
T
F
I
--------------
P
T
A
---
S
T
V
E
--
E
-----
V
-----
T
F
-
Y
V
E
A
G
K
---
K
-
A
L
E
-
S
L
G
L
L
--------
V
E
E
L
----
D
I
-------
A
T
---------------
E
S
L
G
-----------
E
------------
I
-
T
T
K
--
L
R
K
N
D
F
I
Y
V
T
G
G
N
-
T
F
F
L
L
Q
--------
E
-------------
L
--
K
------
R
-----
T
G--------------
A
D
K
L
I
L
E
E
I
A
A
G
K
L
Y
I
G
E
----
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
52.30
13%
-21
- C6 -
2RK3
-
PARK7_HUMAN
A:
[3-108]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
---------
R
A
L
V
I
--------------
L
A
K
---
G
A
E
E
---------------
M
-
E
T
V
I
P
V
---
D
-
V
M
R
-
R
A
G
I
K
--------
V
T
V
A
----
G
L
-------
A
G
K
D
-------------
P
--------------
V
Q
C
SRD
V
V
I
C
P
DA
S
L
E
D
A
K
K
E
G
P
Y
D
V
V
V
L
P
G
G
N
-
L
-------------
G
A
Q
N
----------
L
S
E
S
------
A
-----
A
---------------
V
K
E
I
L
K
E
Q
E
N
R
K
G
L
I
A
T
I
----
C
A
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
51.15
11%
29
- C1 -
3MUU
4
?
A:
[6-740]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FTL
T
S
P
Y
L
G
T
C
SYCHHTVPCFSPVKIEQVWDEADDN
T
I
R
I
Q
T
SAQFGYDQSGAASAN
K
Y
R
Y
M
S
LKQDHT
V
K
E
G
T
M
D
D
I
K
I
S
T
S
G
P
C
R
R
L
S
Y
K
G
--------------------
Y
F
L
L
A
K
C
P
PGD
S
V
T
V
S
I
----------------
V
S
S
N
S
A
T
S
C
---------
T
L
A
R
K
I
K
PKFVGREKYDLP
P
V
H
---
G
K
K
I
--
P
-----
C
T
V
Y
D
R
L
H
-
L
P
F
K
L
I
---
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-
S
T
C
M
V
P
V
A
H
--------
A
P
N
V
----
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H
-------
G
F
---------------
K
--------------
H
------------
I
-
S
L
Q
--
L
D
T
D
H
L
T
L
L
T
T
R
R
-
L
G------------
A
-------------
N
--
P
------
E
-----
P
---------------
T
T
E
W
I
V
G
K
T
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R
N
F
T
V
D
R
D
----
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L
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I
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G
N
H
E
P
V
R
V
-
Y
-
A
-----
Q
E
S
G
G
-------
Y
E
H
A
T
T
V
P
N
V
-
P
Q
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P
Y
K
A
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A
GY
A
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L
E
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M
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S
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V
L
P
S
T
N
Q
-----
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Y
I
T
C
---
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F
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T
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V
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S
P
-
K
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C
C
G
-
S
L
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------
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Q
P
A
A
-
H
A
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---
T
C
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Y
P
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F
M
W
G
G
A
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C
F
-
C
D
S
E
---------
N
S
Q
M
S
E
-
A
Y
V
E
L
S
A
D
C
A
S
D
H
A
-------------
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A
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A
A
M
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V
G
----
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R
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G
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---
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L
D
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Y
V
--
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T
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V
V
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L
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G
A
MKPGAFG
D
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Q
A
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-
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L
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T
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-----------
D
L
I
A
S
T
D
-------
I
R
L
L
K
P
--
S
A
K
N
V
H
V
P
Y
----
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Q
A
-------------
S
S
G
F
E
M
W
K
--
N
N
S
G
-
R
P
L
Q
-
E
T
A
----------------------------------------
P
F
G
C
K
I
--
A
V
N
P
L
R
A
V
D
C
S
Y
G
N
-----
I
-
P
I
S
I
D
I
P
N
----
A
A
F
I
R
T
S
D
A
P
L
V
S
T
V
K
C
E
V
S
E
C
T
Y
S
-----
A
D
F
G
G
M
A
T
-
L
Q
Y
V
S
D
R
E
G
Q
C
P
V
H
S
H
S
S
T
A
T
L
Q
E
S
T
V
H
V
L
E
K
G
A
V
T
V
H
F
S
T
A
S
P
Q
A
N
---
F
I
V
S
------------
L
C
G
K
K
T
T
C
N
A
E
C
-----
7
HHSearch
51.06
14%
-61
- C6 -
3RHT
3
?
A:
[6-89]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
L
Y
C
--------------
G
D
T
---
S
L
E
T
-----------------
A
A
G
Y
L
A
---
G
-
L
M
T
-
S
W
Q
W
E
--------
F
D
Y
I
----
P
S
-------
H
V
---------------
G
--------------
L
D
-----------
V
-
G
E
L
--
L
A
K
Q
D
L
V
I
L
S
D
Y
P
A
E
-------------
R
-------------
M
--
T
------
A
-----
Q
---------------
A
I
D
Q
L
V
T
M
V
K
A
G
C
G
L
V
M
L
----
G
G
W
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
50.38
9%
-45
- C6 -
1Q7R
-
PDXT_GEOSE
A:
[20-104]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
S
N
M
---------
K
I
G
V
L
--------------
G
L
Q
---
G
A
--------------------
V
R
E
H
V
---
R
-
A
I
E
-
A
C
G
A
E
--------
A
V
I
V
----
K
K
-------
S
-----------------------------------------------
E
Q
--
L
E
G
L
D
G
L
V
L
P
G
G
E
-
S
-------------
T
-------------
T
--
M
R
R
L
I
D
R
Y
-----
G
---------------
L
M
E
P
L
K
Q
F
A
A
A
G
K
P
M
F
G
T
----
C
A
G
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
50.15
23%
-59
- C6 -
3TTY
-
?
A:
[427-487]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
H
K
Y
Y
---
D
-
A
L
Y
-
K
Q
N
I
Q
--------
T
D
M
I
----
S
V
-------
E
-----------------------------------------------
E
D
--
L
S
K
Y
K
V
V
I
A
P
V
M
Y
---------------
M
-------------
V
--
K
------
P
-----
G
---------------
F
A
E
R
V
E
R
F
V
A
Q
G
G
T
F
V
T
T
----
F
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
49.11
22%
-36
- C6 -
2GK3
2
?
A:
[41-127]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
T
W
L
L
---
E
-
C
L
R
-
K
G
G
V
D
--------
I
D
Y
M
----
P
A
-------
H
T
---------------
V
Q
I
AFP---------
E
------------
S
-
I
D
E
--
L
N
R
Y
D
V
I
V
I
S
D
I
G
-
S
-------------
N
T
F
L
L
QNETFYQL
K
I
--
K
------
P
-----
N
---------------
A
L
E
S
I
K
E
Y
V
K
N
G
G
G
L
L
M
I
----
G
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
47.97
19%
-31
- C6 -
3SOZ
1
?
A:
[34-120]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
D
Y
L
L
---
S
-
C
L
R
-
Q
G
N
I
D
--------
V
D
Y
M
----
P
A
-------
H
I
V
Q
TRF----------
P
--------------
Q
------------
T
-
A
E
A
--
L
A
C
Y
D
A
I
V
I
S
D
I
G
-
S
N
T
F
L
L
QNRTFYNM
D
-------------
I
--
I
------
P
-----
D
---------------
A
L
Q
L
I
A
D
Y
V
A
E
G
G
G
L
L
M
I
----
G
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
47.57
13%
-36
- C6 -
1KA9
-
HIS5_THET8
H:
[16-85]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
A
A
---
K
-
A
L
E
-
A
A
G
F
S
--------
V
A
V
A
----
Q
D
------------------------------------------------------
P
K
A
--
H
E
E
A
D
L
L
V
L
P
G
Q
G
-
H
-------------
F
GQVMRA-------
F
--
Q
E-----
S
-----
G
---------------
F
V
E
R
V
R
R
H
L
E
R
G
L
P
F
L
G
I
----
C
V
G
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
47.08
22%
-30
- C6 -
1KWG
2
BGAL_THETH
A:
[427-484]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Y
L
F
Y
---
S
-
A
L
R
-
R
L
G
L
D
--------
V
D
V
V
----
P
P
-------
G
-----------------------------------------------
A
S
--
L
R
G
Y
A
F
A
V
V
P
S
L
P
---------------
I
-------------
V
--
R
------
E
-----
E
------------------
A
L
E
A
F
R
E
A
E
G
P
V
L
F
G
----
P
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
46.52
9%
24
- C3 -
2ZXC
7
NCASE_PSEAE
A:
[2-644]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLP
Y
R
F
G
L
G
K
A
D
ITGEAAE
V
G
M
M
GYSSLEQK
T
A
G
I
H
-
M
R
Q
W
A
R
-----
A
F
V
I
E
E
A
ASGR
R
L
V
Y
V
N
T
DLGMIF
Q
A
V
H
L
K
V
L
A
-----
R
L
K
A
K
Y
----------------
P
G
V
Y
D
E
N
N
V
---------
M
L
A
A
T
--------------
H
T
H
---
S
G
P
G
--
G
FSHYA
M
Y
N
L
S
V
L
G
-
F
Q
E
K
T
F
---
N
-
A
I
V
-
D
-
G
I
V
--------
R
S
I
E
----
R
A
-------
Q
A
---------------
R
--------------
L
------------
Q
-
P
G
R
--
L
F
Y
G
S
G
E
L
R
N
A
S
R
-
N
-------------
R
-------------
S
--
L
------
L
-----
S
H
L
KNPDIAGYEDGID
P
Q
M
S
V
L
S
F
V
D
A
N
G
E
L
A
G
A
----
I
S
W
F
P
V
H
S
T
S
M
T
N
A
-
N
-
H
-----
L
I
S
P
D
-------
N
K
G
Y
A
S
Y
H
W
E
-
H
D
V
S
R
K
S
G
--------------
F
-
V
A
A
F
A
Q
T
N
A
G
-----
N
L
S
P
N
---
L
N
L
K
P
G
S
G
P
-
F
-
D
N
E
F
D
-
N
T
-
R
------
E
I
G
L
R
-
Q
F
A
K
---
A
Y
E
I
A
G
Q
A
Q
E
-
E
-
V
L
G
E
L
D
S
-
R
F
R
F
V
--------
D
F
T
-
R
L
-
P
I
R
P
E
F
T
D
G
Q
P
R
Q
L
-------------
C
T
A
A
I
G
T
S
L
-
A
A
G
S
T
E
D
G
P
G
P
L
-
G
L
E
E
G
---
N
N
P
F
L
S
--
A
L
G
G
L
L
T
G
V
P
-
P
-
Q
E
L
-
V
Q
C
Q
A
E
K
T
I
L
A
D
T
G
N
K
K
P
Y
P
W
T
P
T
V
L
-
P
-
I
Q
M
F
R
-------
I
G
Q
L
E
-
L
L
G
A
P
A
-----------
E
F
T
V
M
A
G
V
----
R
I
R
R
A
V
Q
A
A
S
E
A
A
G
I
R
H
V
V
----
F
N
G
Y------------
A
N
A
Y
A
-
S
Y
V
T
T
R
E
E
Y
A
A
Q
E
-
Y
E
G
G
S
TLYGPW
T
Q
A
A
Y
Q
Q
L
F
V
D
M
A
V
A
L
R
E
RLPVETSAIAPDLS
C
C
Q
M
N
F
--
Q
T
G
V
V
A
D
D
P
Y
I
G
K
S
-----
F
G
D
V
L
Q
Q
P
R
E
----
S
Y
R
I
G
D
K
V
T
V
A
F
V
T
G
H
P
K
N
D
L
R
T
E
K
T
F
L
E
V
V
N
I
G
K
-
D
G
-
K
Q
T
P
V
T
V
A
T
D
N
D
---
W
D
T
Q
Y
R
W
E
R
V
G
I
S
-
A
S
K
A
T
I
S
W
S
I
P
P
G
T
E
P
G
H
---
Y
Y
I
R
H
Y
G
N
A
K
N
FWTQ
K
I
S
E
I
G
G
S
T
R
S
F
E
V
L
GT-