@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0365: (2016-03-14 )
MLNADLKQQLKQLLELMEGNVEFVASLGSDEKSKELKELLTEISDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKNLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMSTGEEHLLNLDGIFVQIGLLPNTSWLKDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
Atome Classification :
(22 SA)
.........10........20........30........40........50..--.---...--.-.60........70........80........90........100.......110.......120.......130.......140.......150.......160..--.......170.......180.......190..---..---.---..200.......210.......220.......230....-.------.--.-.240.......250...-.-.-..260.......270.....-..280....--..-.---290---.---.-.....---------.300.......310.......320....----...330.......--340.......350.......360.......370.......380.-.-..-...-390.......400.......-410-.---.......420.......430.......440.......-----450---.........460.-......470.......480-........490.......500.....---
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
ML
N
A
D
L
K
Q
Q
L
K
Q
L
L
E
L
MEG
N
V
E
F
V
A
SLGS
D
E
K
S
K
E
L
K
E
L
L
T
E
I
SDMSPRLSL
S
--
E
---
K
S
L--K-RTPSFSVNRPGEET
G
V
T
F
AGIPLG
H
E
F
N
S
L
V
L
A
I
L
Q
VSGRAP
K
E
K
Q
S
I
I
D
Q
I
K
NLEG
S
F
H
F
E
T
F
I
S
L
T
C
Q
K
C
P
D
V
V
Q
A
L
N
L
M
S
VINPNI
T
H
S
M
ID
G
A
VFREE--SE--
N
I
M
A
V
P
A
V
F
LN
G
E
EFGNG
R
M
T
I
Q
D
I
L
S
KLGST---A
D
---
A
---
S
EFENKEP
Y
D
V
L
I
VGGGPASG
S
A
A
I
Y
T
A
RKG
L
R
-T
G
I
V
A
-
D
------R--I-GGQVNDTAGIE
N
F
I
T
V
K
-E-T-TG
S
E
F
S
S
N
L
A
A
H
I
D
Q
YDI
D
A
-MTGIRATDI--EK-T---D
E
----
A
---
I
-
K
V
T
LE---------N
G
A
V
L
ES
K
T
V
I
I
ATGA
G
W
R
KLNIP
G
E
E
Q
----
L
I
N
KGVAFCPHCD--GPLFENK
D
V
A
V
IGGGNS
G
V
E
A
A
I
D
L
A
G
I
V
N
H
V
T
L
F
E
F
A
S
E
LKA
D
-
N
-
V
L
-
Q
D
R
-
L
R
S
L
SNV
D
I
KTNAK
T
T
E
V
VG-E-D-H---VT
G
I
R
YEDMSTG
E
E
H
L
L
NL
D
G
I
F
V
Q
I
GLLP
N
T
S
W
L
K
D
-----
A
-----
V
ELNERG
E
I
V
I
DR-NNNTNV
P
G
I
F
AAGDVTDQ--KN
K
Q
I
I
I
S
MGAGA
N
A
A
L
N
A
F
D
Y
I
IRN---
102
HHSearch
94.78
54%
-94
- C3 -
1HYU
4
AHPF_SALTY
A:
[1-517]
M
L
D
T
N
M
K
T
Q
L
R
A
Y
L
E
K
L
T
K
P
V
E
L
I
A
T
L
D
D
S
A
K
S
A
E
I
K
E
L
L
A
E
I
A
E
L
S
D
K
V
T
F
K
--
E
D
NT
L
P
V
----
R
K
P
S
F
L
I
T
N
P
G
S
Q
Q
G
P
R
F
A
G
S
P
L
G
H
E
F
T
S
L
V
L
A
L
L
W
T
G
G
H
P
S
K
E
A
Q
S
L
L
E
Q
I
R
D
I
D
G
D
F
E
F
E
T
Y
Y
S
L
S
C
H
N
C
P
D
V
V
Q
A
L
N
L
M
A
V
L
N
P
R
I
K
H
T
A
I
D
G
G
T
F
Q
N
E
I
T
E
R
--
N
V
M
G
V
P
A
V
F
V
N
G
K
E
F
G
Q
G
R
M
T
L
T
E
I
V
A
K
V
D
T
G
---
A
E
---
K
R
A
A
E
A
L
N
K
R
D
A
Y
D
V
L
I
V
G
S
G
P
A
G
A
A
A
A
V
Y
S
A
R
K
G
I
R
-
T
G
L
M
G
-
E
------
R
--
F
-
G
G
Q
V
L
D
T
V
D
I
E
N
Y
I
S
V
P
-
K
-
T
-
E
G
Q
K
L
A
G
A
L
K
A
H
V
S
D
Y
D
V
D
V
-
I
D
S
Q
S
A
S
K
L
--
V
P
-
A
ATE
G
G
----
L
---
H
-
Q
I
E
T
A
---------
S
G
A
V
L
K
A
R
S
I
I
I
A
T
G
A
K
W
R
N
M
N
V
P
G
E
D
Q
----
Y
R
T
K
G
V
T
Y
C
P
H
C
D
--
G
P
L
F
K
G
K
R
V
A
V
I
G
G
G
N
S
G
V
E
A
A
I
D
L
A
G
I
V
E
H
V
T
L
L
E
F
A
P
E
M
K
A
D
-
Q
-
V
L
-
Q
D
K
-
V
R
S
L
K
N
V
D
I
I
L
N
A
Q
T
T
E
V
K
G
-
D
-
G
S
K
---
V
V
G
L
E
Y
R
D
R
V
S
G
D
I
H
S
V
A
L
A
G
I
F
V
Q
I
G
L
L
P
N
T
H
W
L
E
G
-----
A
-----
L
E
R
N
R
M
G
E
I
I
I
D
A
-
K
C
E
T
S
V
K
G
V
F
A
A
G
D
C
T
T
V
--
P
Y
K
Q
I
I
I
A
T
G
E
G
A
K
A
S
L
S
A
F
D
Y
L
I
R
----
3
PsiBlast_PDB
94.22
53%
-92
- C3 -
1HYU
4
AHPF_SALTY
A:
[1-518]
M
L
D
T
N
M
K
T
Q
L
R
A
Y
L
E
K
L
T
K
P
V
E
L
I
A
T
L
D
D
S
A
K
S
A
E
I
K
E
L
L
A
E
I
A
E
L
S
D
K
V
T
F
K
--
E
---
D
N
T
LP
V
-
R
K
P
S
F
L
I
T
N
P
G
S
Q
Q
G
P
R
F
A
G
S
P
L
G
H
E
F
T
S
L
V
L
A
L
L
W
T
G
G
H
P
S
K
E
A
Q
S
L
L
E
Q
I
R
D
I
D
G
D
F
E
F
E
T
Y
Y
S
L
S
C
H
N
C
P
D
V
V
Q
A
L
N
L
M
A
V
L
N
P
R
I
K
H
T
A
I
D
G
G
T
F
Q
N
E
I
T
E
R
--
N
V
M
G
V
P
A
V
F
V
N
G
K
E
F
G
Q
G
R
M
T
L
T
E
I
V
A
K
V
D
T
G
---
A
E
K
R
A
A
---
E
A
L
N
K
R
D
A
Y
D
V
L
I
V
G
S
G
P
A
G
A
A
A
A
V
Y
S
A
R
K
G
I
R
-
T
G
L
M
G
-
E
------
R
--
F
-
G
G
Q
V
L
D
T
V
D
I
E
N
Y
I
S
V
P
-
K
-
T
-
E
G
Q
K
L
A
G
A
L
K
A
H
V
S
D
Y
D
V
D
V
-
I
D
S
Q
S
A
S
K
L
V
P
A
A
-
T
---
E
G
----
G
---
L
H
Q
I
E
T
A
---------
S
G
A
V
L
K
A
R
S
I
I
I
A
T
G
A
K
W
R
N
M
N
V
P
G
E
D
Q
----
Y
R
T
K
G
V
T
Y
C
P
H
C
D
--
G
P
L
F
K
G
K
R
V
A
V
I
G
G
G
N
S
G
V
E
A
A
I
D
L
A
G
I
V
E
H
V
T
L
L
E
F
A
P
E
M
K
A
D
-
Q
-
V
L
-
Q
D
K
-
V
R
S
L
K
N
V
D
I
I
L
N
A
Q
T
T
E
V
K
G
-
D
G
S
-
K
---
V
V
G
L
E
Y
R
D
R
V
S
G
D
I
H
S
V
A
L
A
G
I
F
V
Q
I
G
L
L
P
N
T
H
W
L
E
G
-----
A
-----
L
E
R
N
R
M
G
E
I
I
I
D
A
-
K
C
E
T
S
V
K
G
V
F
A
A
G
D
C
T
T
V
--
P
Y
K
Q
I
I
I
A
T
G
E
G
A
K
A
S
L
S
A
F
D
Y
L
I
R
T
---
92
Fugue
94.06
53%
-94
- C3 -
1HYU
4
AHPF_SALTY
A:
[1-521]
M
L
D
T
N
M
K
T
Q
L
R
A
Y
L
E
K
L
T
K
P
V
E
L
I
A
T
L
D
D
S
A
K
S
A
E
I
K
E
L
L
A
E
I
A
E
L
S
D
K
V
T
F
K
E
D
N
---
T
L
P
--
V
-
R
K
P
S
F
L
I
T
N
P
G
S
Q
Q
G
P
R
F
A
G
S
P
L
G
H
E
F
T
S
L
V
L
A
L
L
W
T
G
G
H
P
S
K
E
A
Q
S
L
L
E
Q
I
R
D
I
D
G
D
F
E
F
E
T
Y
Y
S
L
S
C
H
N
C
P
D
V
V
Q
A
L
N
L
M
A
V
L
N
P
R
I
K
H
T
A
I
D
G
G
T
F
Q
N
E
--
I
T
E
R
N
V
M
G
V
P
A
V
F
V
N
G
K
E
F
G
Q
G
R
M
T
L
T
E
I
V
A
K
V
D
T
G
AEK
R
A
---
A
---
E
A
L
N
K
R
D
A
Y
D
V
L
I
V
G
S
G
P
A
G
A
A
A
A
V
Y
S
A
R
K
G
I
R
-
T
G
L
M
G
-
E
------
R
--
F
-
G
G
Q
V
L
D
T
V
D
I
E
N
Y
I
S
V
P
-
K
-
T
-
E
G
Q
K
L
A
G
A
L
K
A
H
V
S
D
Y
D
V
D
V
-
I
D
S
Q
S
A
S
K
L
--
V
P
-
A
---
A
T
----
E
G
G
L
H
-
Q
I
E
T
A
---------
S
G
A
V
L
K
A
R
S
I
I
I
A
T
G
A
K
W
R
N
M
N
V
P
G
E
D
Q
----
Y
R
T
K
G
V
T
Y
C
P
H
C
D
--
G
P
L
F
K
G
K
R
V
A
V
I
G
G
G
N
S
G
V
E
A
A
I
D
L
A
G
I
V
E
H
V
T
L
L
E
F
A
P
E
M
K
A
D
-
Q
-
V
L
-
Q
D
K
-
V
R
S
L
K
N
V
D
I
I
L
N
A
Q
T
T
E
V
K
G
D
G
-
S
-
K
---
V
V
G
L
E
Y
R
D
R
V
S
G
D
I
H
S
V
A
L
A
G
I
F
V
Q
I
G
L
L
P
N
T
H
W
L
E
G
-----
A
-----
L
E
R
N
R
M
G
E
I
I
I
D
A
-
K
C
E
T
S
V
K
G
V
F
A
A
G
D
C
T
T
V
--
P
Y
K
Q
I
I
I
A
T
G
E
G
A
K
A
S
L
S
A
F
D
Y
L
I
R
T
KIA
2
PsiBlast_PDB
93.21
54%
-100
- C3 -
4YKG
20
?
A:
[1-517]
M
L
D
T
N
M
K
T
Q
L
K
A
Y
L
E
K
L
T
K
P
V
E
L
I
A
T
L
D
D
S
A
K
S
A
E
I
K
E
L
L
A
E
I
A
E
L
S
D
K
V
T
F
K
--
E
D
--
N
S
L
--
P
V
R
K
P
S
F
L
I
T
N
P
G
S
N
Q
G
P
R
F
A
G
S
P
L
G
H
E
F
T
S
L
V
L
A
L
L
W
T
G
G
H
P
S
K
E
A
Q
S
L
L
E
Q
I
R
H
I
D
G
D
F
E
F
E
T
Y
Y
S
L
S
C
H
N
C
P
D
V
V
Q
A
L
N
L
M
S
V
L
N
P
R
I
K
H
T
A
I
D
G
G
T
F
Q
N
E
I
T
D
R
--
N
V
M
G
V
P
A
V
F
V
N
G
K
E
F
G
Q
G
R
M
T
L
T
E
I
V
A
K
I
D
T
G
---
A
E
KR
A
A
---
E
E
L
N
K
R
D
A
Y
D
V
L
I
V
G
S
G
P
A
G
A
A
A
A
I
Y
S
A
R
K
G
I
R
-
T
G
L
M
G
-
E
------
R
--
F
-
G
G
Q
I
L
D
T
V
D
I
E
N
Y
I
S
V
P
-
K
-
T
-
E
G
Q
K
L
A
G
A
L
K
V
H
V
D
E
Y
D
V
D
V
-
I
------
D
S
--
Q
S
-
A
---
S
K
----
L
---
I
-
P
A
A
V
E
G
G
L
H
Q
I
E
T
A
S
G
A
V
L
K
A
R
S
I
I
V
A
T
G
A
K
W
R
N
M
N
V
P
G
E
D
Q
----
Y
R
T
K
G
V
T
Y
-
P
H
C
D
--
G
P
L
F
K
G
K
R
V
A
V
I
G
G
G
N
S
G
V
E
A
A
I
D
L
A
G
I
V
E
H
V
T
L
L
E
F
A
P
E
M
K
A
D
-
Q
-
V
L
-
Q
D
K
-
L
R
S
L
K
N
V
D
I
I
L
N
A
Q
T
T
E
V
K
G
-
D
G
S
-
K
---
V
V
G
L
E
Y
R
D
R
V
S
G
D
I
H
N
I
E
L
A
G
I
F
V
Q
I
G
L
L
P
N
T
N
W
L
E
G
-----
A
-----
V
E
R
N
R
M
G
E
I
I
I
D
A
-
K
C
E
T
N
V
K
G
V
F
A
A
G
D
C
T
T
V
--
P
Y
K
Q
I
I
I
A
T
G
E
G
A
K
A
S
L
S
A
F
D
Y
L
I
R
----
1
PsiBlast_PDB
92.75
54%
-99
- C3 -
4YKF
19
?
A:
[1-517]
M
L
D
T
N
M
K
T
Q
L
K
A
Y
L
E
K
L
T
K
P
V
E
L
I
A
T
L
D
D
S
A
K
S
A
E
I
K
E
L
L
A
E
I
A
E
L
S
D
K
V
T
F
K
--
E
D
--
N
S
L
--
P
V
R
K
P
S
F
L
I
T
N
P
G
S
N
Q
G
P
R
F
A
G
S
P
L
G
H
E
F
T
S
L
V
L
A
L
L
W
T
G
G
H
P
S
K
E
A
Q
S
L
L
E
Q
I
R
H
I
D
G
D
F
E
F
E
T
Y
Y
S
L
S
C
H
N
C
P
D
V
V
Q
A
L
N
L
M
S
V
L
N
P
R
I
K
H
T
A
I
D
G
G
T
F
Q
N
E
I
T
D
R
--
N
V
M
G
V
P
A
V
F
V
N
G
K
E
F
G
Q
G
R
M
T
L
T
E
I
V
A
K
I
D
T
G
---
A
E
KRA
A
---
E
E
L
N
K
R
D
A
Y
D
V
L
I
V
G
S
G
P
A
G
A
A
A
A
I
Y
S
A
R
K
G
I
R
-
T
G
L
M
G
-
E
------
R
--
F
-
G
G
Q
I
L
D
T
V
D
I
E
N
Y
I
S
V
P
-
K
-
T
-
E
G
Q
K
L
A
G
A
L
K
V
H
V
D
E
Y
D
V
D
V
-
I
------
D
S
--
Q
S
-
A
---
S
K
----
L
---
I
-
P
A
A
V
E
G
G
L
H
Q
I
E
T
A
S
G
A
V
L
K
A
R
S
I
I
V
A
T
G
A
K
W
R
N
M
N
V
P
G
E
D
Q
----
Y
R
T
K
G
V
T
Y
C
P
H
C
D
--
G
P
L
F
K
G
K
R
V
A
V
I
G
G
G
N
S
G
V
E
A
A
I
D
L
A
G
I
V
E
H
V
T
L
L
E
F
A
P
E
M
K
A
D
-
Q
-
V
L
-
Q
D
K
-
L
R
S
L
K
N
V
D
I
I
L
N
A
Q
T
T
E
V
K
G
-
D
G
S
-
K
---
V
V
G
L
E
Y
R
D
R
V
S
G
D
I
H
N
I
E
L
A
G
I
F
V
Q
I
G
L
L
P
N
T
N
W
L
E
G
-----
A
-----
V
E
R
N
R
M
G
E
I
I
I
D
A
-
K
C
E
T
N
V
K
G
V
F
A
A
G
D
C
T
T
V
--
P
Y
K
Q
I
I
I
A
T
G
E
G
A
K
A
S
L
S
A
F
D
Y
L
I
R
----
104
HHSearch
72.74
59%
-99
- C3 -
1FL2
5
AHPF_ECOLI
A:
[1-306]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Y
D
V
L
I
V
G
S
G
P
A
G
A
A
A
A
I
Y
S
A
R
K
G
I
R
-
T
G
L
M
G
-
E
------
R
--
F
-
G
G
Q
I
L
D
T
V
D
I
E
N
Y
I
S
V
P
-
K
-
T
-
E
G
Q
K
L
A
G
A
L
K
V
H
V
D
E
Y
D
V
D
V
-
I
D
S
Q
S
A
S
K
L
--
I
P
-
A
AVE
G
G
----
L
---
H
-
Q
I
E
T
A
---------
S
G
A
V
L
K
A
R
S
I
I
V
A
T
G
A
K
W
R
N
M
N
V
P
G
E
D
Q
----
Y
R
T
K
G
V
T
Y
C
P
H
C
D
--
G
P
L
F
K
G
K
R
V
A
V
I
G
G
G
N
S
G
V
E
A
A
I
D
L
A
G
I
V
E
H
V
T
L
L
E
F
A
P
E
M
K
A
D
-
Q
-
V
L
-
Q
D
K
-
L
R
S
L
K
N
V
D
I
I
L
N
A
Q
T
T
E
V
K
G
-
D
-
G
S
K
---
V
V
G
L
E
Y
R
D
R
V
S
G
D
I
H
N
I
E
L
A
G
I
F
V
Q
I
G
L
L
P
N
T
N
W
L
E
G
-----
A
-----
V
E
R
N
R
M
G
E
I
I
I
D
A
-
K
C
E
T
N
V
K
G
V
F
A
A
G
D
C
T
T
V
--
P
Y
K
Q
I
I
I
A
T
G
E
G
A
K
A
S
L
S
A
F
D
Y
L
I
R
----
4
PsiBlast_PDB
69.89
57%
-90
- C3 -
1FL2
5
AHPF_ECOLI
A:
[2-307]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
D
V
L
I
V
G
S
G
P
A
G
A
A
A
A
I
Y
S
A
R
K
G
I
R
-
T
G
L
M
G
-
E
------
R
--
F
-
G
G
Q
I
L
D
T
V
D
I
E
N
Y
I
S
V
P
-
K
-
T
-
E
G
Q
K
L
A
G
A
L
K
V
H
V
D
E
Y
D
V
D
V
-
I
------
D
S
--
Q
S
-
A
---
S
K
----
L
---
I
-
P
A
A
V
E
G
G
L
H
Q
I
E
T
A
S
G
A
V
L
K
A
R
S
I
I
V
A
T
G
A
K
W
R
N
M
N
V
P
G
E
D
Q
----
Y
R
T
K
G
V
T
Y
C
P
H
C
D
--
G
P
L
F
K
G
K
R
V
A
V
I
G
G
G
N
S
G
V
E
A
A
I
D
L
A
G
I
V
E
H
V
T
L
L
E
F
A
P
E
M
K
A
D
-
Q
-
V
L
-
Q
D
K
-
L
R
S
L
K
N
V
D
I
I
L
N
A
Q
T
T
E
V
K
G
-
D
G
S
-
K
---
V
V
G
L
E
Y
R
D
R
V
S
G
D
I
H
N
I
E
L
A
G
I
F
V
Q
I
G
L
L
P
N
T
N
W
L
E
G
-----
A
-----
V
E
R
N
R
M
G
E
I
I
I
D
A
-
K
C
E
T
N
V
K
G
V
F
A
A
G
D
C
T
T
V
--
P
Y
K
Q
I
I
I
A
T
G
E
G
A
K
A
S
L
S
A
F
D
Y
L
I
R
T
---
106
HHSearch
63.55
33%
-95
- C3 -
2Q0L
2
TRXB_HELPY
A:
[1-311]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
D
C
A
I
I
G
G
G
P
A
G
L
S
A
G
L
Y
A
T
R
G
G
V
K
N
A
V
L
F
E
K
G
------
M
--
P
-
G
G
Q
I
T
G
S
S
E
I
E
N
Y
P
G
V
K
-
E
V
V
-
S
G
L
D
F
M
Q
P
W
Q
E
Q
C
F
R
F
G
L
K
H
-
E
M
-
T
A
V
Q
R
V
--
S
K
-
K
---
D
S
----
H
---
F
-
V
I
L
A
E
---------
D
G
K
T
F
E
A
K
S
V
I
I
A
T
G
G
S
P
K
R
T
G
I
K
G
E
S
E
----
Y
W
G
K
G
V
S
T
C
A
T
C
D
--
G
F
F
Y
K
N
K
E
V
A
V
L
G
G
G
D
T
A
V
E
E
A
I
Y
L
A
N
I
C
K
K
V
Y
L
I
H
R
R
D
G
F
R
C
A
-
P
I
T
L
-
E
H
A
-
K
N
N
-
D
K
I
E
F
L
T
P
Y
V
V
E
E
I
K
G
-
D
-
A
S
G
---
V
S
S
L
S
I
K
N
T
A
T
N
E
K
R
E
L
V
V
P
G
F
F
I
F
V
G
Y
D
V
N
N
A
V
L
K
Q
E----
D
NSML-
C
K
C
D
E
Y
G
S
I
V
V
D
F
-
S
M
K
T
N
V
Q
G
L
F
A
A
G
D
I
R
I
F
--
A
P
K
Q
V
V
C
A
A
S
D
G
A
T
A
A
L
S
V
I
S
Y
L
E
H
H
---
109
HHSearch
63.53
33%
-93
- C3 -
3R9U
2
?
A:
[2-313]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
M
L
D
V
A
I
I
G
G
G
P
A
G
L
S
A
G
L
Y
A
T
R
G
G
L
K
N
V
V
M
F
E
K
G
------
M
--
P
-
G
G
Q
I
T
S
S
S
E
I
E
N
Y
P
G
V
A
-
Q
V
M
-
D
G
I
S
F
M
A
P
W
S
E
Q
C
M
R
F
G
L
K
H
-
E
M
-
V
G
V
E
Q
I
--
L
K
N
S
---
D
G
----
S
---
F
-
T
I
K
L
E
---------
G
G
K
T
E
L
A
K
A
V
I
V
C
T
G
S
A
P
K
K
A
G
F
K
G
E
D
E
----
F
F
G
K
G
V
S
T
C
A
T
C
D
--
G
F
F
Y
K
N
K
E
V
A
V
L
G
G
G
D
T
A
L
E
E
A
L
Y
L
A
N
I
C
S
K
I
Y
L
I
H
R
R
D
E
F
R
A
A
P
S
-
T
V
-
E
K
V
-
K
K
N
-
E
K
I
E
L
I
T
S
A
S
V
D
E
V
Y
G
-
D
-
K
M
G
---
V
A
G
V
K
V
K
-
L
K
D
G
S
I
R
D
L
N
V
P
G
I
F
T
F
V
G
L
N
V
R
N
E
I
L
K
Q
DDSKF
L
-----
C
N
M
E
E
G
G
Q
V
S
V
D
L
-
K
M
Q
T
S
V
A
G
L
F
A
A
G
D
L
R
K
D
--
A
P
K
Q
V
I
C
A
A
G
D
G
A
V
A
A
L
S
A
M
A
Y
I
E
S
----
113
HHSearch
63.26
39%
-84
- C3 -
3CTY
2
?
A:
[14-316]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
D
F
D
V
V
I
V
G
A
G
A
A
G
F
S
A
A
V
Y
A
A
R
S
G
F
S
-
V
A
I
L
D
K
A
------
V
--
A
-
G
G
L
T
A
E
A
P
L
V
E
N
Y
L
G
F
K
-
S
-
I
-
V
G
S
E
L
A
K
L
F
A
D
H
A
A
N
-
Y
A
K
I
-
R
E
G
V
E
V
R
S
I
--
K
K
-
T
---
Q
G
----
G
---
F
-
D
I
E
T
N
----------
D
D
T
Y
H
A
K
Y
V
I
I
T
T
G
T
T
H
K
H
L
G
V
K
G
E
S
E
----
Y
F
G
K
G
T
S
Y
C
S
T
C
D
--
G
Y
L
F
K
G
K
R
V
V
T
I
G
G
G
N
S
G
A
I
A
A
I
S
M
S
E
Y
V
K
N
V
T
I
I
E
Y
M
P
K
Y
M
C
E
-
N
-
A
Y
-
V
Q
E
-
I
K
K
-
R
N
I
P
Y
I
M
N
A
Q
V
T
E
I
V
G
-
D
-
G
K
K
---
V
T
G
V
K
Y
K
D
R
T
T
G
E
E
K
L
I
E
T
D
G
V
F
I
Y
V
G
L
I
P
Q
T
S
F
L
K
D
S----
G
-----
V
K
L
D
E
R
G
Y
I
V
V
D
S
-
R
Q
R
T
S
V
P
G
V
Y
A
A
G
D
V
T
S
G
--
N
F
A
Q
I
A
S
A
V
G
D
G
C
K
A
A
L
S
L
Y
S
D
S
I
-----
14
PsiBlast_PDB
63.21
32%
-97
- C3 -
2Q0K
3
TRXB_HELPY
A:
[3-308]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
C
A
I
I
G
G
G
P
A
G
L
S
A
G
L
Y
A
T
R
G
G
V
K
-
N
A
V
L
F
-
E
------
K
G
M
P
-
G
G
Q
I
T
G
S
S
E
I
E
N
Y
P
G
V
K
-
E
-
V
V
S
G
L
D
F
M
Q
P
W
Q
E
Q
C
F
R
F
G
L
K
H
E
M
T
A
V
Q
--
R
V
--
S
K
-
K
---
D
S
----
H
---
F
-
V
I
L
A
E
---------
D
G
K
T
F
E
A
K
S
V
I
I
A
T
G
G
S
P
K
R
T
G
I
K
G
E
S
E
----
Y
W
G
K
G
V
S
T
C
A
T
C
D
--
G
F
F
Y
K
N
K
E
V
A
V
L
G
G
G
D
T
A
V
E
E
A
I
Y
L
A
N
I
C
K
K
V
Y
L
I
H
R
R
D
G
F
R
C
A
-
P
-
I
T
-
L
E
H
-
A
K
N
N
D
K
I
E
F
L
T
P
Y
V
V
E
E
I
K
G
-
D
A
S
-
G
---
V
S
S
L
S
I
K
N
T
A
T
N
E
K
R
E
L
V
V
P
G
F
F
I
F
V
G
Y
D
V
N
N
A
V
L
K
Q
-----
E
DNSML
C
K
C
D
E
Y
G
S
I
V
V
D
F
-
S
M
K
T
N
V
Q
G
L
F
A
A
G
D
I
R
I
F
--
A
P
K
Q
V
V
C
A
A
S
D
G
A
T
A
A
L
S
V
I
S
Y
L
------
21
PsiBlast_CBE
62.99
39%
-86
- C3 -
3CTY
2
?
B:
[13-312]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
R
D
F
D
V
V
I
V
G
A
G
A
A
G
F
S
A
A
V
Y
A
A
R
S
G
F
S
-
V
A
I
L
D
-
K
------
A
--
V
A
G
G
L
T
A
E
A
P
L
V
E
N
Y
L
G
F
K
-
S
-
I
-
V
G
S
E
L
A
K
L
F
A
D
H
A
A
N
Y
-
A
K
I
-
R
E
G
V
E
V
R
S
I
--
K
K
-
T
---
Q
G
----
G
---
F
-
D
I
E
T
----------
N
D
D
T
Y
H
A
K
Y
V
I
I
T
T
G
T
T
H
K
H
L
G
V
K
G
E
S
E
----
Y
F
G
K
G
T
S
Y
C
S
T
C
D
--
G
Y
L
F
K
G
K
R
V
V
T
I
G
G
G
N
S
G
A
I
A
A
I
S
M
S
E
Y
V
K
N
V
T
I
I
E
Y
M
P
K
Y
M
C
E
-
N
-
A
Y
-
V
Q
E
-
I
K
K
-
R
N
I
P
Y
I
M
N
A
Q
V
T
E
I
V
G
-
D
G
K
-
K
---
V
T
G
V
K
Y
K
D
R
T
T
G
E
E
K
L
I
E
T
D
G
V
F
I
Y
V
G
L
I
P
Q
T
S
F
L
K
D
-----
S
G----
V
K
L
D
E
R
G
Y
I
V
V
D
S
-
R
Q
R
T
S
V
P
G
V
Y
A
A
G
D
V
T
S
G
--
N
F
A
Q
I
A
S
A
V
G
D
G
C
K
A
A
L
S
L
Y
---------
7
PsiBlast_PDB
62.75
39%
-86
- C3 -
3CTY
2
?
A:
[14-312]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
D
F
D
V
V
I
V
G
A
G
A
A
G
F
S
A
A
V
Y
A
A
R
S
G
F
S
-
V
A
I
L
D
-
K
------
A
--
V
A
G
G
L
T
A
E
A
P
L
V
E
N
Y
L
G
F
K
-
S
-
I
-
V
G
S
E
L
A
K
L
F
A
D
H
A
A
N
Y
-
A
K
I
-
R
E
G
V
E
V
R
S
I
--
K
K
-
T
---
Q
G
----
G
---
F
-
D
I
E
T
----------
N
D
D
T
Y
H
A
K
Y
V
I
I
T
T
G
T
T
H
K
H
L
G
V
K
G
E
S
E
----
Y
F
G
K
G
T
S
Y
C
S
T
C
D
--
G
Y
L
F
K
G
K
R
V
V
T
I
G
G
G
N
S
G
A
I
A
A
I
S
M
S
E
Y
V
K
N
V
T
I
I
E
Y
M
P
K
Y
M
C
E
-
N
-
A
Y
-
V
Q
E
-
I
K
K
-
R
N
I
P
Y
I
M
N
A
Q
V
T
E
I
V
G
-
D
G
K
-
K
---
V
T
G
V
K
Y
K
D
R
T
T
G
E
E
K
L
I
E
T
D
G
V
F
I
Y
V
G
L
I
P
Q
T
S
F
L
K
D
-----
S
G----
V
K
L
D
E
R
G
Y
I
V
V
D
S
-
R
Q
R
T
S
V
P
G
V
Y
A
A
G
D
V
T
S
G
--
N
F
A
Q
I
A
S
A
V
G
D
G
C
K
A
A
L
S
L
Y
---------
103
HHSearch
62.70
32%
-85
* C3 *
3F8D
3
?
A:
[10-318]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
P
G
E
K
F
D
V
I
I
V
G
L
G
P
A
A
Y
G
A
A
L
Y
S
A
R
Y
M
L
K
-
T
L
V
I
G
-
E
------
T
--
P
-
G
G
Q
L
T
E
A
G
I
V
D
D
Y
L
G
L
I
-
E
-
I
-
Q
A
S
D
M
I
K
V
F
N
K
H
I
E
K
Y
E
V
P
V
-
L
L
D
-
I
V
E
K
I
--
E
N
-
R
---------
E
---
F
-
V
V
K
T
K
---------
R
K
G
E
F
K
A
D
S
V
I
L
G
I
G
V
K
R
R
K
L
G
V
P
G
E
Q
E
----
F
A
G
R
G
I
S
Y
C
S
V
A
D
--
A
P
L
F
K
N
R
V
V
A
V
I
G
G
G
D
S
A
L
E
G
A
E
I
L
S
S
Y
S
T
K
V
Y
L
I
H
R
R
D
T
F
K
A
Q
-
P
I
Y
V
-
E
T
V
-
K
K
K
-
P
N
V
E
F
V
L
N
S
V
V
K
E
I
K
G
-
D
-
K
-
V
---
V
K
Q
V
V
V
E
N
L
K
T
G
E
I
K
E
L
N
V
N
G
V
F
I
E
I
G
F
D
P
P
T
D
F
A
K
S
N
----
G
-----
I
E
T
D
T
N
G
Y
I
K
V
D
E
-
W
M
R
T
S
V
P
G
V
F
A
A
G
D
C
T
S
A
WL
G
F
R
Q
V
I
T
A
V
A
Q
G
A
V
A
A
T
S
A
Y
R
Y
V
T
E
----
15
PsiBlast_PDB
62.64
32%
-94
- C3 -
2Q0L
2
TRXB_HELPY
A:
[3-308]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
C
A
I
I
G
G
G
P
A
G
L
S
A
G
L
Y
A
T
R
G
G
V
K
-
N
A
V
L
F
-
E
------
K
GM
P
-
G
G
Q
I
T
G
S
S
E
I
E
N
Y
P
G
V
K
-
E
-
V
V
S
G
L
D
F
M
Q
P
W
Q
E
Q
C
F
R
F
G
L
K
H
E
M
T
A
V
Q
--
R
V
--
S
K
-
K
---
D
S
----
H
---
F
-
V
I
L
A
E
---------
D
G
K
T
F
E
A
K
S
V
I
I
A
T
G
G
S
P
K
R
T
G
I
K
G
E
S
E
----
Y
W
G
K
G
V
S
T
C
A
T
C
D
--
G
F
F
Y
K
N
K
E
V
A
V
L
G
G
G
D
T
A
V
E
E
A
I
Y
L
A
N
I
C
K
K
V
Y
L
I
H
R
R
D
G
F
R
C
A
-
P
-
I
T
-
L
E
H
-
A
K
N
N
D
K
I
E
F
L
T
P
Y
V
V
E
E
I
K
G
-
D
A
S
-
G
---
V
S
S
L
S
I
K
N
T
A
T
N
E
K
R
E
L
V
V
P
G
F
F
I
F
V
G
Y
D
V
N
N
A
V
L
K
Q
-----
E
DNSML
C
K
C
D
E
Y
G
S
I
V
V
D
F
-
S
M
K
T
N
V
Q
G
L
F
A
A
G
D
I
R
I
F
--
A
P
K
Q
V
V
C
A
A
S
D
G
A
T
A
A
L
S
V
I
S
Y
L
------
35
PsiBlast_CBE
62.53
32%
-98
- C3 -
2Q0L
2
TRXB_HELPY
B:
[3-308]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
C
A
I
I
G
G
G
P
A
G
L
S
A
G
L
Y
A
T
R
G
G
V
K
-
N
A
V
L
F
-
E
------
K
GM
P
-
G
G
Q
I
T
G
S
S
E
I
E
N
Y
P
G
V
K
-
E
-
V
V
S
G
L
D
F
M
Q
P
W
Q
E
Q
C
F
R
F
G
L
K
H
E
M
T
A
V
Q
--
R
V
--
S
K
-
K
---
D
S
----
H
---
F
-
V
I
L
A
E
---------
D
G
K
T
F
E
A
K
S
V
I
I
A
T
G
G
S
P
K
R
T
G
I
K
G
E
S
E
----
Y
W
G
K
G
V
S
T
C
A
T
C
D
--
G
F
F
Y
K
N
K
E
V
A
V
L
G
G
G
D
T
A
V
E
E
A
I
Y
L
A
N
I
C
K
K
V
Y
L
I
H
R
R
D
G
F
R
C
A
-
P
-
I
T
-
L
E
H
-
A
K
N
N
D
K
I
E
F
L
T
P
Y
V
V
E
E
I
K
G
-
D
A
S
-
G
---
V
S
S
L
S
I
K
N
T
A
T
N
E
K
R
E
L
V
V
P
G
F
F
I
F
V
G
Y
D
V
N
N
A
V
L
K
Q
-----
E
DNSML
C
K
C
D
E
Y
G
S
I
V
V
D
F
-
S
M
K
T
N
V
Q
G
L
F
A
A
G
D
I
R
I
F
--
A
P
K
Q
V
V
C
A
A
S
D
G
A
T
A
A
L
S
V
I
S
Y
L
------
16
PsiBlast_PDB
62.17
32%
-93
- C3 -
3ISH
2
TRXB_HELPY
A:
[3-308]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
C
A
I
I
G
G
G
P
A
G
L
S
A
G
L
Y
A
T
R
G
G
V
K
-
N
A
V
L
F
-
E
------
K
GM
P
-
G
G
Q
I
T
G
S
S
E
I
E
N
Y
P
G
V
K
-
E
-
V
V
S
G
L
D
F
M
Q
P
W
Q
E
Q
C
F
R
F
G
L
K
H
E
M
T
A
V
Q
--
R
V
--
S
K
-
K
---
D
S
----
H
---
F
-
V
I
L
A
E
---------
D
G
K
T
F
E
A
K
S
V
I
I
A
T
G
G
S
P
K
R
T
G
I
K
G
E
S
E
----
Y
W
G
K
G
V
S
T
C
A
T
C
D
--
G
F
F
Y
K
N
K
E
V
A
V
L
G
G
G
D
T
A
V
E
E
A
I
Y
L
A
N
I
C
K
K
V
Y
L
I
H
R
R
D
G
F
R
C
A
-
P
-
I
T
-
L
E
H
-
A
K
N
N
D
K
I
E
F
L
T
P
Y
V
V
E
E
I
K
G
-
D
A
S
-
G
---
V
S
S
L
S
I
K
N
T
A
T
N
E
K
R
E
L
V
V
P
G
F
F
I
F
V
G
Y
D
V
N
N
A
V
L
K
Q
-----
E
DNSML
C
K
C
D
E
Y
G
S
I
V
V
D
F
-
S
M
K
T
N
V
Q
G
L
F
A
A
G
D
I
R
I
F
--
A
P
K
Q
V
V
C
A
A
S
D
G
A
T
A
A
L
S
V
I
S
Y
L
------
34
PsiBlast_CBE
61.83
32%
-93
- C3 -
3ISH
2
TRXB_HELPY
B:
[3-308]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
C
A
I
I
G
G
G
P
A
G
L
S
A
G
L
Y
A
T
R
G
G
V
K
-
N
A
V
L
F
-
E
------
K
GM
P
-
G
G
Q
I
T
G
S
S
E
I
E
N
Y
P
G
V
K
-
E
-
V
V
S
G
L
D
F
M
Q
P
W
Q
E
Q
C
F
R
F
G
L
K
H
E
M
T
A
V
Q
--
R
V
--
S
K
-
K
---
D
S
----
H
---
F
-
V
I
L
A
E
---------
D
G
K
T
F
E
A
K
S
V
I
I
A
T
G
G
S
P
K
R
T
G
I
K
G
E
S
E
----
Y
W
G
K
G
V
S
T
C
A
T
C
D
--
G
F
F
Y
K
N
K
E
V
A
V
L
G
G
G
D
T
A
V
E
E
A
I
Y
L
A
N
I
C
K
K
V
Y
L
I
H
R
R
D
G
F
R
C
A
-
P
-
I
T
-
L
E
H
-
A
K
N
N
D
K
I
E
F
L
T
P
Y
V
V
E
E
I
K
G
-
D
A
S
-
G
---
V
S
S
L
S
I
K
N
T
A
T
N
E
K
R
E
L
V
V
P
G
F
F
I
F
V
G
Y
D
V
N
N
A
V
L
K
Q
-----
E
DNSML
C
K
C
D
E
Y
G
S
I
V
V
D
F
-
S
M
K
T
N
V
Q
G
L
F
A
A
G
D
I
R
I
F
--
A
P
K
Q
V
V
C
A
A
S
D
G
A
T
A
A
L
S
V
I
S
Y
L
------
114
HHSearch
61.76
32%
-83
- C3 -
1VDC
2
TRXB1_ARATH
A:
[4-323]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
T
H
N
T
R
L
C
I
V
G
S
G
P
A
A
H
T
A
A
I
Y
A
A
R
A
E
L
K
-
P
L
L
F
E
-
G
WMANDI
A
--
P
-
G
G
Q
L
T
T
T
T
D
V
E
N
F
P
G
F
P
-
E
G
I
-
L
G
V
E
L
T
D
K
F
R
K
Q
S
E
R
F
G
T
T
I
-
F
T
-
E
T
V
T
K
V
--
D
F
-
S
---
S
K
----
P
---
F
-
K
L
F
T
----------
D
S
K
A
I
L
A
D
A
V
I
L
A
I
G
A
V
A
K
R
L
S
F
V
G
S
G
E
VLGG
F
W
N
R
G
I
S
A
C
A
V
C
D
GA
A
P
I
F
R
N
K
P
L
A
V
I
G
G
G
D
S
A
M
E
E
A
N
F
L
T
K
Y
G
S
K
V
Y
I
I
H
R
R
D
A
F
R
A
S
-
K
-
I
M
Q
Q
R
A
-
L
S
N
-
P
K
I
D
V
I
W
N
S
S
V
V
E
A
Y
G
-
D
-
G
-
E
RDV
L
G
G
L
K
V
K
N
V
V
T
G
D
V
S
D
L
K
V
S
G
L
F
F
A
I
G
H
E
P
A
T
K
F
L
D
G
-----
G
-----
V
E
L
D
S
D
G
Y
V
V
T
K
P
G
T
T
Q
T
S
V
P
G
V
F
A
A
G
D
V
Q
D
K
--
K
Y
R
Q
A
I
T
A
A
G
T
G
C
M
A
A
L
D
A
E
H
Y
L
Q
-----
36
PsiBlast_CBE
61.73
32%
-95
- C3 -
2Q0K
3
TRXB_HELPY
B:
[3-308]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
C
A
I
I
G
G
G
P
A
G
L
S
A
G
L
Y
A
T
R
G
G
V
K
-
N
A
V
L
F
-
E
------
K
GM
P
-
G
G
Q
I
T
G
S
S
E
I
E
N
Y
P
G
V
K
-
E
-
V
V
S
G
L
D
F
M
Q
P
W
Q
E
Q
C
F
R
F
G
L
K
H
E
M
T
A
V
Q
--
R
V
--
S
K
-
K
---
D
S
----
H
---
F
-
V
I
L
A
E
---------
D
G
K
T
F
E
A
K
S
V
I
I
A
T
G
G
S
P
K
R
T
G
I
K
G
E
S
E
----
Y
W
G
K
G
V
S
T
C
A
T
C
D
--
G
F
F
Y
K
N
K
E
V
A
V
L
G
G
G
D
T
A
V
E
E
A
I
Y
L
A
N
I
C
K
K
V
Y
L
I
H
R
R
D
G
F
R
C
A
-
P
-
I
T
-
L
E
H
-
A
K
N
N
D
K
I
E
F
L
T
P
Y
V
V
E
E
I
K
G
-
D
A
S
-
G
---
V
S
S
L
S
I
K
N
T
A
T
N
E
K
R
E
L
V
V
P
G
F
F
I
F
V
G
Y
D
V
N
N
A
V
L
K
Q
-----
E
DNSML
C
K
C
D
E
Y
G
S
I
V
V
D
F
-
S
M
K
T
N
V
Q
G
L
F
A
A
G
D
I
R
I
F
--
A
P
K
Q
V
V
C
A
A
S
D
G
A
T
A
A
L
S
V
I
S
Y
L
------
111
HHSearch
61.13
34%
-86
- C3 -
2Q7V
2
?
A:
[5-313]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
H
D
Y
D
V
V
I
I
G
G
G
P
A
G
L
T
A
A
I
Y
T
G
R
A
Q
L
S
-
T
L
I
L
E
K
G
------
M
--
P
-
G
G
Q
I
A
W
S
E
E
V
E
N
F
P
G
F
P
-
E
P
I
-
A
G
M
E
L
A
Q
R
M
H
Q
Q
A
E
K
F
G
A
K
V
-
E
M
-
D
E
V
Q
G
V
--
Q
H
-
D
---
A
T
SHPY
P
---
F
-
T
V
R
G
Y
----------
N
G
E
Y
R
A
K
A
V
I
L
A
T
G
A
D
P
R
K
L
G
I
P
G
E
D
N
----
F
W
G
K
G
V
S
T
C
A
T
C
D
--
G
F
F
Y
K
G
K
K
V
V
V
I
G
G
G
D
A
A
V
E
E
G
M
F
L
T
K
F
A
D
E
V
T
V
I
H
R
R
D
T
L
R
A
N
-
K
V
A
Q
-
A
R
A
-
F
A
N
-
P
K
M
K
F
I
W
D
T
A
V
E
E
I
Q
G
-
A
-
D
-
S
---
V
S
G
V
K
L
R
N
L
K
T
G
E
V
S
E
L
A
T
D
G
V
F
I
F
I
G
H
V
P
N
T
A
F
V
K
D
-----
T
-----
V
S
L
R
D
D
G
Y
V
D
V
R
D
-
E
I
Y
T
N
I
P
M
L
F
A
A
G
D
V
S
D
Y
--
I
Y
R
Q
L
A
T
S
V
G
A
G
T
R
A
A
M
M
T
E
R
Q
L
A
A
----
112
HHSearch
60.53
31%
-79
- C3 -
2A87
5
TRXB_MYCTU
A:
[10-317]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
H
H
P
V
R
D
V
I
V
I
G
S
G
P
A
G
Y
T
A
A
L
Y
A
A
R
A
Q
L
A
-
P
L
V
F
E
G
T
------
S
--
F
-
G
G
A
L
M
T
T
T
D
V
E
N
Y
P
G
F
R
N
G
-
I
-
T
G
P
E
L
M
D
E
M
R
E
Q
A
L
R
F
G
A
D
L
-
R
M
E
-
D
V
E
S
V
--
S
L
-
H
---
G
P
----
L
---
K
-
S
V
V
T
A
---------
D
G
Q
T
H
R
A
R
A
V
I
L
A
M
G
A
A
A
R
Y
L
Q
V
P
G
E
Q
E
----
L
L
G
R
G
V
S
S
C
A
T
C
D
--
G
F
F
F
R
D
Q
D
I
A
V
I
G
G
G
D
S
A
M
E
E
A
T
F
L
T
R
F
A
R
S
V
T
L
V
H
R
R
D
E
F
R
A
S
-
K
-
I
M
-
L
D
R
A
R
N
N
-
D
K
I
R
F
L
T
N
H
T
V
V
A
V
D
G
-
D
-
T
-
T
---
V
T
G
L
R
V
R
D
T
N
T
G
A
E
T
T
L
P
V
T
G
V
F
V
A
I
G
H
E
P
R
S
G
L
V
R
E
-----
A
-----
I
D
V
D
P
D
G
Y
V
L
V
Q
G
R
T
T
S
T
S
L
P
G
V
F
A
A
G
D
L
V
D
R
--
T
Y
R
Q
A
V
T
A
A
G
S
G
C
A
A
A
I
D
A
E
R
W
L
A
E
----