@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1078: (2016-03-21 )
MSFFKRLKDKFATNKENEEVKSLREEQGQDKLEDTHSEGSTQDVNDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVIVEKIVEIYHQEDDNSEAMNIEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVGVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNALSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNDEITTVENDQIVTEEKDDNHGAK
Atome Classification :
(50 SA)
.........10........20........30........40........50........60........70........80........90........100.......110-.....-...120---...---.....130.......140.....----..----150--...--.....160.......170..---------.---..-..180-.----.-..----....190.......200.....-..210.......220.......230....-...---240-..-......-250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......---380.......390.......400.......410....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
S
F
F
K
R
L
K
D
K
FATNK
E
N
E
E
V
K
S
L
R
E
E
QGQ
D
K
L
E
DTHSEGSTQ
D
V
N
D
L
A
E
N
A
E
V
K
KKPRKLSEADFDDD
G
L
I
S
I
E
D
F
E
E
I
E
A
Q
K
MG
A
K
F
K
A
G
L
E
K
S
R
Q
N
F
Q
E
Q
L
N
N
L
I
A
R
Y
-
R
-KV
D
E
D
-
F
F
E
A
L
----
E
E
M
---
L
I
TADVG
F
N
T
V
M
T
L
T
E
E
L
R
M
E
A
Q
----RR----NI---Q
D
T
--
E
D
L
R
E
V
I
V
E
K
I
V
E
I
Y
HQEDD---------N---SE-AMN-I-E----D-G
R
----
L
N
V
I
L
M
V
GVNGVGKTT
T
I
G
K
L
A
-
Y
R
Y
KMEG
K
K
V
M
L
AAGDTFRAG
A
I
D
Q
L
K
V
W
-
G
E
R---VG--
V
D
-
V
ISQSE-GSD
P
A
A
V
M
Y
D
A
I
N
AAKNKG
V
D
I
L
I
CDTAGRLQ
N
K
T
N
L
M
Q
E
L
E
K
V
K
R
V
I
N
RAVPDAPH
E
A
L
L
C
L
DATTG
Q
N
A
L
S
Q
A
R
N
F
K
E
V
TNV
T
G
I
V
L
T
KLDGTAKG
G
I
V
L
A
IRNELH
I
P
V
K
Y
VGLGEQLDDLQPFNP
E
---
S
Y
V
Y
G
L
F
A
D
M
IEQNDE
I
T
TVEND
Q
I
V
TEEKDDNHGAK
82
HHSearch
95.73
53%
-97
- C6 -
1VMA
1
?
A:
[13-305]
---------------------------------------------------------------------------------
M
G
L
F
D
F
L
K
K
G
L
Q
K
T
K
E
T
F
F
G
R
V
V
K
L
L
-
K
G
-
K
-
K
L
D
D
E
-
T
R
E
E
L
----
E
E
L
---
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
E
E
K
D
G
---------------------
D
A
L
E
S
L
K
E
I
I
L
E
I
L
N
F
D
---------------
T
K
--
L
N
-
V
-
P
----
P
-
E
P
----
P
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
-
K
M
F
V
D
E
G
K
S
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
-
G
E
R
---
V
G
--
A
T
-
V
I
S
H
S
E
-
G
A
D
P
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
---
A
F
V
E
V
L
L
S
-----------------------------
1
PsiBlast_PDB
94.46
49%
-107
- C6 -
2YHS
5
FTSY_ECOLI
A:
[197-494]
-------------------------------------------------------------------------------------
A
R
L
K
R
S
L
L
K
T
K
E
N
L
G
S
G
F
I
S
L
F
-
R
G
-
K
-
K
I
D
D
D
-
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
----
R
K
----
Q
L
---
R
D
A
--
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
---------------
E
-
P
L
N
-
V
-
E
----
G
-
K
A
----
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
-
R
Q
F
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-
G
Q
R
---
N
N
--
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
-----------------------------
7
PsiBlast_PDB
94.43
51%
-91
- C6 -
1VMA
1
?
A:
[19-306]
---------------------------------------------------------------------------------------
L
K
K
G
L
Q
K
T
K
E
T
F
F
G
R
V
V
K
L
L
-
K
G
-
K
-
K
L
D
D
E
-
T
R
E
E
L
----
E
E
L
---
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
----
E
----
E
K
----
D
G
---
D
A
L
--
E
S
L
K
E
I
I
L
E
I
L
--------
N
---------
F
---
D
T
-
K
L
N
-
V
-
P
----
P
-
E
P
----
P
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
-
K
M
F
V
D
E
G
K
S
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
-
G
E
R
---
V
G
--
A
T
-
V
I
S
H
S
E
-
G
A
D
P
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
---
A
F
V
E
V
L
L
S
E
----------------------------
23
PsiBlast_CBE
94.35
51%
-95
- C6 -
1VMA
1
?
B:
[19-306]
---------------------------------------------------------------------------------------
L
K
K
G
L
Q
K
T
K
E
T
F
F
G
R
V
V
K
L
L
-
K
G
-
K
-
K
L
D
D
E
-
T
R
E
E
L
----
E
E
L
---
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
----
E
----
E
K
----
D
G
---
D
A
L
--
E
S
L
K
E
I
I
L
E
I
L
--------
N
---------
F
---
D
T
-
K
L
N
-
V
-
P
----
P
-
E
P
----
P
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
-
K
M
F
V
D
E
G
K
S
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
-
G
E
R
---
V
G
--
A
T
-
V
I
S
H
S
E
-
G
A
D
P
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
---
A
F
V
E
V
L
L
S
E
----------------------------
4
PsiBlast_PDB
94.27
50%
-105
- C6 -
1FTS
-
FTSY_ECOLI
A:
[203-494]
-------------------------------------------------------------------------------------------
L
L
K
T
K
E
N
L
G
S
G
F
I
S
L
F
-
R
G
-
K
-
K
I
D
D
D
-
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
----
R
K
----
Q
L
---
R
D
A
--
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
---------------
E
-
P
L
N
-
V
-
E
----
G
-
K
A
----
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
-
R
Q
F
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-
G
Q
R
---
N
N
--
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
-----------------------------
2
PsiBlast_PDB
93.95
49%
-102
- C6 -
2QY9
-
FTSY_ECOLI
A:
[196-494]
------------------------------------------------------------------------------------
F
A
R
L
K
R
S
L
L
K
T
K
E
N
L
G
S
G
F
I
S
L
F
-
R
G
-
K
-
K
I
D
D
D
-
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
----
R
K
----
Q
L
---
R
D
A
--
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
---------------
E
-
P
L
N
-
V
-
E
----
G
-
K
A
----
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
-
R
Q
F
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-
G
Q
R
---
N
N
--
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
-----------------------------
8
PsiBlast_PDB
93.91
44%
-110
- C6 -
1ZU4
1
FTSY_MYCMS
A:
[13-314]
---------------------------------------------------------------------------------------------
K
S
A
F
N
F
S
K
D
I
K
K
L
S
K
K
Y
-
K
-
Q
A
D
D
E
-
F
F
E
E
L
----
E
D
V
---
L
I
Q
T
D
M
G
M
K
M
V
L
K
V
S
N
L
V
R
K
K
T
K
----
R
-----------
D
T
S
F
E
N
I
K
D
A
L
V
E
S
L
Y
Q
A
Y
T
D
N
D
W
-----------------
Y
R
-
I
-
D
FK--
E
-
N
R
----
L
N
I
F
M
L
V
G
V
N
G
T
G
K
T
T
S
L
A
K
M
A
-
N
Y
Y
A
E
L
G
Y
K
V
L
I
A
A
A
D
T
F
R
A
G
A
T
Q
Q
L
E
E
W
I
K
T
R
---
L
N
NK
V
D
-
L
V
K
A
N
K
L
N
A
D
P
A
S
V
V
F
D
A
I
K
K
A
K
E
Q
N
Y
D
L
L
L
I
D
T
A
G
R
L
Q
N
K
T
N
L
M
A
E
L
E
K
M
N
K
I
I
Q
Q
V
E
K
S
A
P
H
E
V
L
L
V
I
D
A
T
T
G
Q
N
G
V
I
Q
A
E
E
F
S
K
V
A
D
V
S
G
I
I
L
T
K
M
D
S
T
S
K
G
G
I
G
L
A
I
K
E
L
L
N
I
P
I
K
M
I
G
V
G
E
K
V
D
D
L
L
A
F
D
I
D
---
Q
Y
I
V
H
L
S
S
G
F
M
-
Q
------------------------
72
HHSearch
93.74
48%
-105
- C6 -
2YHS
5
FTSY_ECOLI
A:
[190-495]
------------------------------------------------------------------------------
P
T
K
E
G
F
F
A
R
L
K
R
S
L
L
K
T
K
E
N
L
G
S
G
F
I
S
L
F
R
-
G
-
K
-
K
I
D
D
D
-
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
----
R
K
----
Q
L
---
R
D
A
--
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
---------------
D
E
-
P
L
N
-
V
-
E
----
G
-
K
A
----
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
-
R
Q
F
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-
G
Q
R
---
N
N
--
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
R
----------------------------
5
PsiBlast_PDB
93.57
50%
-106
- C6 -
3ZN8
-
FTSY_ECOLI
D:
[3-294]
-------------------------------------------------------------------------------------------
L
L
K
T
K
E
N
L
G
S
G
F
I
S
L
F
-
R
G
-
K
-
K
I
D
D
D
-
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
----
R
K
----
Q
L
---
R
D
A
--
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
---------------
E
-
P
L
N
-
V
-
E
----
G
-
K
A
----
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
-
R
Q
F
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-
G
Q
R
---
N
N
--
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
-----------------------------
9
PsiBlast_PDB
93.30
44%
-110
- C6 -
1ZU5
-
FTSY_MYCMS
A:
[104-404]
---------------------------------------------------------------------------------------------
K
S
A
F
N
F
S
K
D
I
K
K
L
S
K
K
Y
-
K
-
Q
A
D
D
E
-
F
F
E
E
L
----
E
D
V
---
L
I
Q
T
D
M
G
M
K
M
V
L
K
V
S
N
L
V
R
K
K
T
K
----
R
-----------
D
T
S
F
E
N
I
K
D
A
L
V
E
S
L
Y
Q
A
Y
T
D
N
D
W
---------
T
---
N
K
-
K
Y
R
-
I
-
D
FK--
E
-
N
R
----
L
N
I
F
M
L
V
G
V
N
G
T
G
K
T
T
S
L
A
K
M
A
-
N
Y
Y
A
E
L
G
Y
K
V
L
I
A
A
A
D
T
F
R
A
G
A
T
Q
Q
L
E
E
W
I
K
T
R
---
L
N
NK
V
D
-
L
V
K
A
N
K
L
N
A
D
P
A
S
V
V
F
D
A
I
K
K
A
K
E
Q
N
Y
D
L
L
L
I
D
T
A
G
R
L
Q
N
K
T
N
L
M
A
E
L
E
K
M
N
K
I
I
Q
Q
V
E
K
S
A
P
H
E
V
L
L
V
I
D
A
T
T
G
Q
N
G
V
I
Q
A
E
E
F
S
K
V
A
D
V
S
G
I
I
L
T
K
M
D
S
T
S
K
G
G
I
G
L
A
I
K
E
L
L
N
I
P
I
K
M
I
G
V
G
E
K
V
D
D
L
L
A
F
D
I
D
---
Q
Y
I
V
H
L
S
S
G
F
M
--------------------------
3
PsiBlast_PDB
92.49
49%
-104
- C6 -
2XXA
3
FTSY_ECOLI
B:
[20-299]
-------------------------------------------------------------------------------------------------------
I
S
L
F
-
R
G
-
K
-
K
I
D
D
D
-
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
----
R
K
----
Q
L
---
R
D
A
--
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
---------------
E
-
P
L
N
-
V
-
E
----
G
-
K
A
----
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
-
R
Q
F
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-
G
Q
R
---
N
N
--
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
-----------------------------
21
PsiBlast_CBE
92.15
49%
-103
- C6 -
2XXA
3
FTSY_ECOLI
D:
[20-299]
-------------------------------------------------------------------------------------------------------
I
S
L
F
-
R
G
-
K
-
K
I
D
D
D
-
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
----
R
K
----
Q
L
---
R
D
A
--
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
---------------
E
-
P
L
N
-
V
-
E
----
G
-
K
A
----
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
-
R
Q
F
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-
G
Q
R
---
N
N
--
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
-----------------------------
22
PsiBlast_CBE
92.14
51%
-108
- C6 -
4C7O
5
FTSY_ECOLI
D:
[2-275]
---------------------------------------------------------------------------------------------------------------
K
-
K
I
D
D
D
-
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
----
R
K
----
Q
L
---
R
D
A
--
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
---------------
E
-
P
L
N
-
V
-
E
----
G
-
K
A
----
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
-
R
Q
F
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-
G
Q
R
---
N
N
--
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
-----------------------------
73
HHSearch
91.11
40%
-109
- C6 -
3B9Q
1
CFTSY_ARATH
A:
[1-302]
-------------------------------------------------------------------------------------
E
K
V
F
S
G
F
S
K
T
R
E
N
L
A
V
-
I
D
E
L
L
L
F
W
-
N
L
A
E
T
D
R
-
V
L
D
E
L
----
E
E
A
---
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
D
I
M
----
S
G
----
K
L
---
K
S
G
--
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
--
S
---------
K
---
T
E
--
L
Q
-
L
-
G
----
F
-
R
K
----
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
-
H
R
L
K
N
E
G
T
K
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
-
A
E
R
---
T
G
--
C
E
-
I
V
V
A
E
--
K
A
K
A
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
---
A
F
V
N
A
I
F
S
-----------------------------
6
PsiBlast_PDB
90.83
51%
-102
- C6 -
4C7O
4
FTSY_ECOLI
B:
[5-275]
-------------------------------------------------------------------------------------------------------------------
D
D
D
-
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
----
R
K
----
Q
L
---
R
D
A
--
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
---------------
E
-
P
L
N
-
V
-
E
----
G
-
K
A
----
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
-
R
Q
F
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
-
G
Q
R
---
N
N
--
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
---
D
F
I
E
A
L
F
A
-----------------------------
12
PsiBlast_PDB
89.99
40%
-108
- C6 -
3B9Q
1
CFTSY_ARATH
A:
[2-302]
--------------------------------------------------------------------------------------
K
V
F
S
G
F
S
K
T
R
E
N
L
A
-
V
I
D
E
L
L
L
F
W
-
N
-
L
A
E
T
D
R
V
L
D
E
L
----
E
E
A
---
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
D
I
M
----
S
G
----
K
L
---
K
S
G
--
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
--
S
---------
K
---
T
E
--
L
Q
-
L
-
G
----
F
-
R
K
----
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
-
H
R
L
K
N
E
G
T
K
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
-
A
E
R
---
T
G
--
C
E
I
V
V
A
E
---
K
A
K
A
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
---
A
F
V
N
A
I
F
S
-----------------------------
71
HHSearch
88.46
40%
-106
* C6 *
2OG2
2
CFTSY_ARATH
A:
[55-359]
----------------------------------------------------------------------------------
S
D
V
E
K
V
F
S
G
F
S
K
T
R
E
N
L
A
V
-
I
D
E
L
L
L
F
W
N
L
-
A
E
T
D
R
-
V
L
D
E
L
----
E
E
A
---
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
D
I
M
----
S
G
----
K
L
---
K
S
G
--
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
K
---------------
T
E
--
L
Q
-
L
-
G
----
F
-
R
K
----
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
-
H
R
L
K
N
E
G
T
K
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
-
A
E
R
---
T
G
--
C
E
-
I
V
V
A
E
G
D
K
A
K
A
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
---
A
F
V
N
A
I
F
S
-----------------------------
85
HHSearch
88.30
44%
-111
- C6 -
1ZU4
1
FTSY_MYCMS
A:
[32-314]
------------------------------------------------------------------------------------------------------------------
A
D
D
E
-
F
F
E
E
L
----
E
D
V
---
L
I
Q
T
D
M
G
M
K
M
V
L
K
V
S
N
L
V
R
K
K
T
K
----
R
D
---------
T
S
F
--
E
N
I
K
D
A
L
V
E
S
L
Y
Q
A
Y
T
D
N
D
W
--------------
Y
-
R
I
D
-
F
-
K
----
E
-
N
R
----
L
N
I
F
M
L
V
G
V
N
G
T
G
K
T
T
S
L
A
K
M
A
-
N
Y
Y
A
E
L
G
Y
K
V
L
I
A
A
A
D
T
F
R
A
G
A
T
Q
Q
L
E
E
W
-
I
K
T
RLN
N
K
--
V
D
-
L
V
K
A
N
K
L
N
A
D
P
A
S
V
V
F
D
A
I
K
K
A
K
E
Q
N
Y
D
L
L
L
I
D
T
A
G
R
L
Q
N
K
T
N
L
M
A
E
L
E
K
M
N
K
I
I
Q
Q
V
E
K
S
A
P
H
E
V
L
L
V
I
D
A
T
T
G
Q
N
G
V
I
Q
A
E
E
F
S
K
V
A
D
V
S
G
I
I
L
T
K
M
D
S
T
S
K
G
G
I
G
L
A
I
K
E
L
L
N
I
P
I
K
M
I
G
V
G
E
K
V
D
D
L
L
A
F
D
I
D
---
Q
Y
I
V
H
L
S
S
G
F
M
Q
-------------------------
11
PsiBlast_PDB
88.25
40%
-106
- C6 -
2OG2
2
CFTSY_ARATH
A:
[59-359]
--------------------------------------------------------------------------------------
K
V
F
S
G
F
S
K
T
R
E
N
L
A
-
V
I
D
E
L
L
L
F
W
-
N
-
L
A
E
T
D
R
V
L
D
E
L
----
E
E
A
---
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
D
I
M
----
S
G
----
K
L
---
K
S
G
--
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
------------
K
---
T
E
--
L
Q
-
L
-
G
----
F
-
R
K
----
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
-
H
R
L
K
N
E
G
T
K
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
-
A
E
R
---
T
G
--
C
E
I
V
V
A
E
G
D
-
K
A
K
A
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
---
A
F
V
N
A
I
F
S
-----------------------------
86
HHSearch
88.01
47%
-103
- C6 -
1RJ9
3
FTSY_THEAQ
A:
[27-303]
------------------------------------------------------------------------------------------------------------------
N
L
E
E
-
V
L
E
E
L
----
E
M
A
---
L
L
A
A
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
S
G
R
--------------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
E
R
---------
R
A
T
L
R
K
L
G
F
N
-
P
-
Q
KPKP
V
E
P
K
----
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
-
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
-
G
K
R
---
L
S
--
I
P
-
V
I
Q
G
P
E
-
G
T
D
S
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
-----------------------------
30
PsiBlast_CBE
86.86
46%
-97
- C6 -
1RJ9
3
FTSY_THEAQ
A:
[43-303]
------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
S
G
R
----
K
----------------
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
E
R
R
A
T
L
R
K
L
G
F
N
---
P
Q
-
K
P
K
-
P
-
V
----
E
-
P
K
----
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
-
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
-
G
K
R
---
L
S
--
I
P
-
V
I
Q
G
P
E
-
G
T
D
S
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
-----------------------------
17
PsiBlast_PDB
86.33
47%
-99
- C6 -
2Q9C
8
FTSY_THEAQ
A:
[43-304]
------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
S
G
R
----
K
----------------
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
E
R
R
A
T
L
R
K
L
GF
N
---
P
Q
-
K
P
K
-
P
-
V
----
E
-
P
K
----
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
-
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
-
G
K
R
---
L
S
--
I
P
-
V
I
Q
G
P
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
D
----------------------------
20
PsiBlast_PDB
85.81
47%
-107
- C6 -
2IYL
3
FTSY_THEAQ
D:
[23-284]
------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
S
G
R
----
K
----------------
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
--ATLRKLGF-
N
---
P
Q
-
K
---
P
-
V
----
E
-
P
K
----
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
-
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
------
T
Q
L
S
E
W
-
G
K
R
---
L
S
--
I
P
-
V
I
Q
G
P
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
--
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
D
----------------------------
16
PsiBlast_PDB
85.13
47%
-98
- C6 -
2Q9B
12
FTSY_THEAQ
A:
[43-303]
------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
S
G
R
----
K
----------------
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
E
R
R
A
T
L
R
K
L
GF
N
---
P
Q
-
K
P
K
-
P
-
V
----
E
-
P
K
----
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
-
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
-
G
K
R
---
L
S
--
I
P
-
V
I
Q
G
P
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
-----------------------------
27
PsiBlast_CBE
85.10
47%
-98
- C6 -
2J7P
9
FTSY_THEAQ
E:
[22-282]
------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
S
G
R
----
K
----------------
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
-----------------------
P
-
V
----
E
-
P
K
----
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
-
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
-
G
K
R
---
L
S
--
I
P
-
V
I
Q
G
P
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
-----------------------------
13
PsiBlast_PDB
84.99
47%
-102
- C6 -
1OKK
8
FTSY_THEAQ
D:
[42-302]
------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
S
G
R
----
K
----------------
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
-----------------------
P
-
V
----
E
-
P
K
----
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
-
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
-
G
K
R
---
L
S
--
I
P
-
V
I
Q
G
P
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
-----------------------------
18
PsiBlast_PDB
84.95
47%
-98
- C6 -
2J7P
7
FTSY_THEAQ
D:
[22-282]
------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
S
G
R
----
K
----------------
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
---------------------
K
-
P
-
V
----
E
-
P
K
----
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
-
R
Y
Y
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
-
G
K
R
---
L
S
--
I
P
-
V
I
Q
G
P
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
---
A
F
V
E
A
L
L
E
-----------------------------
79
HHSearch
78.30
35%
-98
- C6 -
3DM5
10
SRP54_PYRFU
A:
[26-319]
-----------------------------------------------------------------------------------------------------------------
A
L
I
K
E
-
L
V
R
D
I
----
Q
R
A
---
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
----
E
E
KPPA
G
I
---
S
K
K
--
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
---------------
A
K
-
P
I
E
-
I
------
K
-
E
K
----
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
-
R
Y
F
Q
K
R
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
-
L
D
R
---
Y
H
--
I
E
-
V
F
G
N
P
Q
-
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
Q
I
S
N
V
I
------
H
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
---
R
F
V
S
R
L
L
G
L
G
D
I
Q
------------------------
51
PsiBlast_CBE
78.28
37%
-80
- C6 -
2J7P
7
SRP54_THEAQ
B:
[8-285]
-------------------------------------------------------------------------------------------------
R
L
Q
E
A
I
G
R
L
R
G
R
G
-
R
-
I
T
E
E
D
-
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
----
G
K
----
Q
V
---
L
E
S
--
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
---------
G
---
E
A
-
R
L
P
-
V
-
L
----
K
-
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-
G
E
K
---
V
G
--
V
P
-
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
----------------------------------------
49
PsiBlast_CBE
77.79
37%
-82
- C6 -
3NG1
7
SRP54_THEAQ
B:
[8-285]
-------------------------------------------------------------------------------------------------
R
L
Q
E
A
I
G
R
L
R
G
R
G
-
R
-
I
T
E
E
D
-
L
K
A
T
L
----
R
E
I
RRA
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
----
G
K
----
Q
V
---
L
E
S
--
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
---------
G
---
E
A
-
R
L
P
-
V
-
L
----
K
-
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-
G
E
K
---
V
G
--
V
P
-
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
----------------------------------------
52
PsiBlast_CBE
77.73
37%
-78
- C6 -
2J7P
10
SRP54_THEAQ
A:
[8-285]
-------------------------------------------------------------------------------------------------
R
L
Q
E
A
I
G
R
L
R
G
R
G
-
R
-
I
T
E
E
D
-
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
----
G
K
----
Q
V
---
L
E
S
--
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
---------
G
---
E
A
-
R
L
P
-
V
-
L
----
K
-
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-
G
E
K
---
V
G
--
V
P
-
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
----------------------------------------
48
PsiBlast_CBE
77.66
37%
-79
- C6 -
1JPJ
1
SRP54_THEAQ
A:
[8-285]
-------------------------------------------------------------------------------------------------
R
L
Q
E
A
I
G
R
L
R
G
R
G
-
R
-
I
T
E
E
D
-
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
----
G
K
----
Q
V
---
L
E
S
--
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
---------
G
---
E
A
-
R
L
P
-
V
-
L
----
K
-
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-
G
E
K
---
V
G
--
V
P
-
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
----------------------------------------
57
PsiBlast_CBE
77.52
37%
-79
- C6 -
1NG1
13
SRP54_THEAQ
A:
[8-285]
-------------------------------------------------------------------------------------------------
R
L
Q
E
A
I
G
R
L
R
G
R
G
-
R
-
I
T
E
E
D
-
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
----
G
K
----
Q
V
---
L
E
S
--
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
---------
G
---
E
A
-
R
L
P
-
V
-
L
----
K
-
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-
G
E
K
---
V
G
--
V
P
-
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
----------------------------------------
34
PsiBlast_CBE
77.49
39%
-93
- C6 -
3DMD
6
?
A:
[49-324]
-------------------------------------------------------------------------------------------------------------------
E
K
D
-
V
D
K
A
L
----
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
----
G
K
----
K
V
---
R
I
G
--
T
D
K
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
---------
T
---
S
R
-
R
I
D
L
I
-
E
----
E
-
I
R
K
AEK
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
-
N
W
L
K
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
-
A
K
R
---
I
G
--
V
K
-
V
I
K
H
S
Y
-
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
---
W
F
L
E
R
I
F
G
-----------------------------
65
PsiBlast_CBE
77.45
32%
-94
- C6 -
4C7O
5
SRP54_ECOLI
C:
[9-297]
--------------------------------------------------------------------------------------------------
L
S
R
T
L
R
N
I
S
G
R
G
-
R
-
L
T
E
D
N
-
V
K
D
T
L
----
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
K
----
S
L
---
T
P
G
--
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
---------------
Q
-
T
L
N
-
L
-
A
----
A
-
Q
P
----
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
-
A
E
Q
---
V
G
--
V
D
-
F
F
P
S
D
V
-
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
S
I
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
-------------------------------
50
PsiBlast_CBE
77.38
37%
-82
- C6 -
3NG1
6
SRP54_THEAQ
A:
[8-285]
-------------------------------------------------------------------------------------------------
R
L
Q
E
A
I
G
R
L
R
G
R
G
-
R
-
I
T
E
E
D
-
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
----
G
K
----
Q
V
---
L
E
S
--
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
---------
G
---
E
A
-
R
L
P
-
V
-
L
----
K
-
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-
G
E
K
---
V
G
--
V
P
-
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
----------------------------------------
44
PsiBlast_CBE
77.35
37%
-80
- C6 -
1O87
7
SRP54_THEAQ
A:
[8-285]
-------------------------------------------------------------------------------------------------
R
L
Q
E
A
I
G
R
L
R
G
R
G
-
R
-
I
T
E
E
D
-
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
----
G
K
----
Q
V
---
L
E
S
--
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
---------
G
---
E
A
-
R
L
P
-
V
-
L
----
K
-
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-
G
E
K
---
V
G
--
V
P
-
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
----------------------------------------
36
PsiBlast_CBE
77.34
37%
-89
- C6 -
3DM5
10
SRP54_PYRFU
A:
[17-314]
----------------------------------------------------------------------------------------------------------
I
A
R
A
-
S
-
S
V
D
E
A
-
L
I
K
E
L
V
R
D
I
Q
R
A
---
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
----
Q
----
R
R
----
A
L
---
E
E
K
--
P
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
------
G
---
T
E
-
A
K
P
-
I
-
E
I---
K
-
E
K
----
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
-
R
Y
F
Q
K
R
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
-
L
D
R
---
Y
H
--
I
E
-
V
F
G
N
P
Q
-
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
Q
I
S
N
V
I
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
---
R
F
V
S
R
L
L
G
-----------------------------
46
PsiBlast_CBE
77.28
37%
-76
- C6 -
1JPN
4
SRP54_THEAQ
B:
[8-285]
-------------------------------------------------------------------------------------------------
R
L
Q
E
A
I
G
R
L
R
G
R
G
-
R
-
I
T
E
E
D
-
L
K
A
T
L
----
R
E
I
RRA
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
----
G
K
----
Q
V
---
L
E
S
--
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
---------
G
---
E
A
-
R
L
P
-
V
-
L
----
K
-
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-
G
E
K
---
V
G
--
V
P
-
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
----------------------------------------
33
PsiBlast_CBE
77.06
39%
-93
- C6 -
3DMD
4
?
B:
[49-324]
-------------------------------------------------------------------------------------------------------------------
E
K
D
-
V
D
K
A
L
----
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
----
G
K
----
K
V
---
R
I
G
--
T
D
K
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
---------
T
---
S
R
-
R
I
D
L
I
-
E
----
E
-
I
R
K
AEK
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
-
N
W
L
K
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
-
A
K
R
---
I
G
--
V
K
-
V
I
K
H
S
Y
-
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
---
W
F
L
E
R
I
F
G
-----------------------------
35
PsiBlast_CBE
77.02
37%
-88
- C6 -
3DM5
9
SRP54_PYRFU
B:
[17-315]
----------------------------------------------------------------------------------------------------------
I
A
R
A
-
S
-
S
V
D
E
A
-
L
I
K
E
L
V
R
D
I
Q
R
A
---
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
----
Q
----
R
R
----
A
L
---
E
E
K
--
P
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
------
G
---
T
E
-
A
K
P
-
I
-
E
I---
K
-
E
K
----
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
-
R
Y
F
Q
K
R
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
-
L
D
R
---
Y
H
--
I
E
-
V
F
G
N
P
Q
-
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
-
M
K
Q
I
S
N
V
I
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
---
R
F
V
S
R
L
L
G
-----------------------------
43
PsiBlast_CBE
77.01
37%
-78
- C6 -
1O87
7
SRP54_THEAQ
B:
[8-285]
-------------------------------------------------------------------------------------------------
R
L
Q
E
A
I
G
R
L
R
G
R
G
-
R
-
I
T
E
E
D
-
L
K
A
T
L
----
R
E
I
RRA
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
----
G
K
----
Q
V
---
L
E
S
--
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
---------
G
---
E
A
-
R
L
P
-
V
-
L
----
K
-
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-
G
E
K
---
V
G
--
V
P
-
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
----------------------------------------
56
PsiBlast_CBE
76.84
37%
-78
- C6 -
1OKK
16
SRP54_THEAQ
A:
[8-285]
-------------------------------------------------------------------------------------------------
R
L
Q
E
A
I
G
R
L
R
G
R
G
-
R
-
I
T
E
E
D
-
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
----
G
K
----
Q
V
---
L
E
S
--
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
---------
G
---
E
A
-
R
L
P
-
V
-
L
----
K
-
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-
G
E
K
---
V
G
--
V
P
-
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
----------------------------------------
58
PsiBlast_CBE
76.61
37%
-79
- C6 -
2NG1
4
SRP54_THEAQ
A:
[7-284]
-------------------------------------------------------------------------------------------------
R
L
Q
E
A
I
G
R
L
R
G
R
G
-
R
-
I
T
E
E
D
-
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
----
G
K
----
Q
V
---
L
E
S
--
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
---------
G
---
E
A
-
R
L
P
-
V
-
L
----
K
-
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-
G
E
K
---
V
G
--
V
P
-
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
----------------------------------------
47
PsiBlast_CBE
76.57
37%
-78
- C6 -
1JPN
4
SRP54_THEAQ
A:
[8-285]
-------------------------------------------------------------------------------------------------
R
L
Q
E
A
I
G
R
L
R
G
R
G
-
R
-
I
T
E
E
D
-
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
----
G
K
----
Q
V
---
L
E
S
--
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
---------
G
---
E
A
-
R
L
P
-
V
-
L
----
K
-
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
-
L
Y
Y
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
-
G
E
K
---
V
G
--
V
P
-
V
L
E
V
M
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
----------------------------------------
32
PsiBlast_CBE
76.52
39%
-94
- C6 -
3DMD
7
?
C:
[49-324]
-------------------------------------------------------------------------------------------------------------------
E
K
D
-
V
D
K
A
L
----
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
----
G
K
----
K
V
---
R
I
G
--
T
D
K
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
---------
T
---
S
R
-
R
I
D
L
I
-
E
----
E
-
I
R
K
AEK
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
-
N
W
L
K
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
-
A
K
R
---
I
G
--
V
K
-
V
I
K
H
S
Y
-
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
---
W
F
L
E
R
I
F
G
-----------------------------
66
PsiBlast_CBE
76.40
32%
-95
- C6 -
4C7O
4
SRP54_ECOLI
A:
[9-296]
--------------------------------------------------------------------------------------------------
L
S
R
T
L
R
N
I
S
G
R
G
-
R
-
L
T
E
D
N
-
V
K
D
T
L
----
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
HEV
N
K
----
S
L
---
T
P
G
--
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
---------------
Q
-
T
L
N
-
L
-
A
----
A
-
Q
P
----
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
-
A
E
Q
---
V
G
--
V
D
-
F
F
P
S
D
V
-
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
S
I
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
--------------------------------
31
PsiBlast_CBE
76.34
39%
-90
- C6 -
3E70
3
?
C:
[49-324]
-------------------------------------------------------------------------------------------------------------------
E
K
D
-
V
D
K
A
L
----
D
E
L
EID
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
----
G
K
----
K
V
---
R
I
G
-----
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
---------
T
---
S
R
-
R
I
D
L
I
-
E
----
E
-
I
R
KAEK
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
-
N
W
L
K
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
-
A
K
R
---
I
G
--
V
K
-
V
I
K
H
S
Y
-
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
---
W
F
L
E
R
I
F
G
-----------------------------
80
HHSearch
75.34
40%
-88
- C6 -
3E70
3
?
C:
[50-324]
-----------------------------------------------------------------------------------------------------------------
K
D
V
D
K
-
A
L
D
E
L
----
E
I
D
---
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
----
G
K
----
K
V
RIG--
G
--
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
R
---------
I
---
D
L
-
I
E
E
-
I
R
K
----
A
-
E
K
----
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
-
N
W
L
K
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
-
A
K
R
---
I
G
--
V
K
-
V
I
K
H
S
Y
-
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
------
T
K
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
---
W
F
L
E
R
I
F
G
-----------------------------
59
PsiBlast_CBE
73.89
37%
-71
- C6 -
1RJ9
3
SRP54_THEAQ
B:
[14-285]
-------------------------------------------------------------------------------------------------------
G
R
L
R
G
R
G
-
R
-
I
T
E
E
D
-
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
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R
V
R
E
E
A
L
----
G
K
----
Q
V
---
L
E
S
--
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
---------
G
---
E
A
-
R
L
P
-
V
-
L
----
K
-
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
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L
A
-
L
Y
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A
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L
L
-
G
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---
V
G
--
V
P
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V
L
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V
M
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-
G
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S
P
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S
I
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R
R
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G
R
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Q
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D
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P
L
M
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
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A
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H
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P
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G
L
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F
Y
P
E
----------------------------------------