@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA2072: (2016-03-31 )
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTTKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSKHIDQLIQTLNINHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG
Atome Classification :
(45 SA)
------....-.....--10---.------..------...-...20........30.........40........50........60--.........70------........80..--......90........--------100------.---------.--------.--------...------..----.110----......-..120-------..----......130.......140.......150.......160.......170.......180.......190.......200----------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------
M
L
K
I
-
N
V
K
Y
Q
--L----K------N
T
------
L
I
R
-
I
N
IDDTEP
K
I
Y
A
V
R-GPSGI
G
K
T
T
V
L
N
M
I
A
G
L
R
K
AD
E
A
I
I
E
VN
G
Q
---
L
L
TDTTKN
V
N
V
------
K
I
Q
Q
R
R
I
G
Y
L
F
Q
--
D
Y
QLFPN
M
T
V
Y
K
N
I
T
F
--------M--------A---------E--------
P
--------
S
K
H
------
I
D
----
Q
L
-
I
----
Q
T
L
N
I
N
-
H
L
M
K
--------QY----PMTLSGG
E
A
Q
R
V
A
L
A
R
ALSTKP
D
L
I
L
LDEPFSSLDDTTKD
E
S
I
T
L
V
K
R
I
F
N
EWQ
I
P
I
I
F
V
THSNY
E
A
E
Q
M
A
H
E
I
I
TIG-----------------------------------------------------------------------------------------------------------------------------------------
102
Fugue
90.26
33%
-128
- C1 -
1Z47
1
?
A:
[11-355]
GSMT
I
E
F
V
G
V
-
E
K
I
Y
P
--
G
----
G
------
A
R
------
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
-
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
---
R
V
T
D
------
L
------
P
P
Q
K
R
N
V
G
L
V
F
Q
--
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
S
F
--------
G
--------
L
---------
R
E
K
RVP
K
D
E
M
--------
D
A
R
------
V
R
----
E
L
-
L
----
R
F
M
R
L
E
-
S
Y
A
N
--------
R
F
----
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
EGNVE
Q
F
G
T
P
E
E
V
Y
EKPGT
L
F
V
A
S
F
IGE
S
N
V
W
T
R
A
V
Q
NG
R
I
E
V
AG
A
A
L
P
V
DPAVSEG
S
E
V
A
V
V
V
R
PKD
V
E
L
Q
P
A
S
EREAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R--
110
HHSearch
87.63
34%
-123
- C1 -
1Z47
1
?
A:
[15-220]
-------
I
E
F
V
G
V
E
K
I
--
Y
----
P
GGA---
R
S
------
V
R
G
-
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
-
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
---
R
V
T
D
L
------------
P
P
Q
K
R
N
V
G
L
V
F
Q
--
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
S
F
--------
G
--------
L
---------
R
--------
E
K
RVP
K
D
E
M
D
A
R
------
V
R
----
E
L
-
L
----
R
F
M
R
L
E
-
S
Y
A
N
--------
R
F
----
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
-----------------------------------------------------------------------------------------------------------------------------------------
114
HHSearch
86.70
36%
-115
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[5-218]
-------
L
H
I
G
H
L
S
K
S
--
F
QN--
T
------
P
V
------
L
N
D
-
I
S
L
S
L
D
P
G
E
I
L
F
I
I
-
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
---
T
I
F
S
K
--
N
T
N
L
------
P
V
R
E
R
R
L
G
Y
L
V
Q
--
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
--------
G
--------
L
---------
G
--------
N
GKGRT
A
Q
E
R
Q
R
------
I
E
----
A
M
-
L
----
E
L
T
G
I
S
-
E
L
A
G
--------
R
Y
----
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
-----------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
86.58
37%
-113
- C1 -
2ONK
2
WTPC_ARCFU
F:
[2-200]
------
F
L
K
V
-
R
A
E
K
R
--
L
----
G
------
N
--------
F
R
-
L
N
V
D
F
E
M
G
R
D
Y
C
V
L
L
G
P
T
G
A
G
K
S
V
F
L
E
L
I
A
G
I
V
K
P
D
R
G
E
V
R
L
N
G
A
---
D
I
T
P
L
P
P
------------
E
R
R
G
I
G
F
V
P
Q
--
D
Y
A
L
F
P
H
L
S
V
Y
R
N
I
A
Y
GLRNVE--
R
--------
V
---------
E
--------
R
--------
D
R
R
------
V
R
----
E
M
-
A
----
E
K
L
G
I
A
-
H
L
L
D
--------
R
K
----
P
A
R
L
S
G
G
E
R
Q
R
V
A
L
A
R
A
L
V
I
Q
P
R
L
L
L
L
D
E
P
L
S
A
V
D
L
K
T
K
G
V
L
M
E
E
L
R
F
V
Q
R
E
F
D
V
P
I
L
H
V
T
H
D
L
I
E
A
A
M
L
A
D
E
V
A
V
M
------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
86.44
37%
-113
- C1 -
2ONK
2
WTPC_ARCFU
G:
[2-200]
------
F
L
K
V
-
R
A
E
K
R
--
L
----
G
------
N
--------
F
R
-
L
N
V
D
F
E
M
G
R
D
Y
C
V
L
L
G
P
T
G
A
G
K
S
V
F
L
E
L
I
A
G
I
V
K
P
D
R
G
E
V
R
L
N
G
A
---
D
I
T
P
L
P
P
------------
E
R
R
G
I
G
F
V
P
Q
--
D
Y
A
L
F
P
H
L
S
V
Y
R
N
I
A
Y
GLRNVE--
R
--------
V
---------
E
--------
R
--------
D
R
R
------
V
R
----
E
M
-
A
----
E
K
L
G
I
A
-
H
L
L
D
--------
R
K
----
P
A
R
L
S
G
G
E
R
Q
R
V
A
L
A
R
A
L
V
I
Q
P
R
L
L
L
L
D
E
P
L
S
A
V
D
L
K
T
K
G
V
L
M
E
E
L
R
F
V
Q
R
E
F
D
V
P
I
L
H
V
T
H
D
L
I
E
A
A
M
L
A
D
E
V
A
V
M
------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
86.23
37%
-110
- C1 -
2ONK
2
WTPC_ARCFU
A:
[2-200]
------
F
L
K
V
-
R
A
E
K
R
--
L
----
G
------
N
--------
F
R
-
L
N
V
D
F
E
M
G
R
D
Y
C
V
L
L
G
P
T
G
A
G
K
S
V
F
L
E
L
I
A
G
I
V
K
P
D
R
G
E
V
R
L
N
G
A
---
D
I
T
P
L
P
P
------------
E
R
R
G
I
G
F
V
P
Q
--
D
Y
A
L
F
P
H
L
S
V
Y
R
N
I
A
Y
GLRNVE--
R
--------
V
---------
E
--------
R
--------
D
R
R
------
V
R
----
E
M
-
A
----
E
K
L
G
I
A
-
H
L
L
D
--------
R
K
----
P
A
R
L
S
G
G
E
R
Q
R
V
A
L
A
R
A
L
V
I
Q
P
R
L
L
L
L
D
E
P
L
S
A
V
D
L
K
T
K
G
V
L
M
E
E
L
R
F
V
Q
R
E
F
D
V
P
I
L
H
V
T
H
D
L
I
E
A
A
M
L
A
D
E
V
A
V
M
------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
86.03
37%
-114
- C1 -
2ONK
2
WTPC_ARCFU
B:
[2-200]
------
F
L
K
V
-
R
A
E
K
R
--
L
----
G
------
N
--------
F
R
-
L
N
V
D
F
E
M
G
R
D
Y
C
V
L
L
G
P
T
G
A
G
K
S
V
F
L
E
L
I
A
G
I
V
K
P
D
R
G
E
V
R
L
N
G
A
---
D
I
T
P
L
P
P
------------
E
R
R
G
I
G
F
V
P
Q
--
D
Y
A
L
F
P
H
L
S
V
Y
R
N
I
A
Y
GLRNVE--
R
--------
V
---------
E
--------
R
--------
D
R
R
------
V
R
----
E
M
-
A
----
E
K
L
G
I
A
-
H
L
L
D
--------
R
K
----
P
A
R
L
S
G
G
E
R
Q
R
V
A
L
A
R
A
L
V
I
Q
P
R
L
L
L
L
D
E
P
L
S
A
V
D
L
K
T
K
G
V
L
M
E
E
L
R
F
V
Q
R
E
F
D
V
P
I
L
H
V
T
H
D
L
I
E
A
A
M
L
A
D
E
V
A
V
M
------------------------------------------------------------------------------------------------------------------------------------------
112
HHSearch
84.81
39%
-116
- C1 -
2IT1
-
?
A:
[4-208]
-------
I
K
L
E
N
I
V
K
K
--
F
----
G
NF----
T
A
------
L
N
N
-
I
N
L
K
I
K
D
G
E
F
M
A
L
L
-
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
E
K
---
D
V
T
E
L
------------
P
P
K
D
R
N
V
G
L
V
F
Q
--
N
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
F
--------
P
--------
L
---------
E
--------
L
R
KAP
R
E
E
I
D
K
K
------
V
R
----
E
V
-
A
----
K
M
L
H
I
D
-
K
L
L
N
--------
R
Y
----
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
-----------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
84.16
39%
-119
- C1 -
2IT1
1
?
B:
[22-207]
------------------------------------------
I
N
L
K
I
K
D
G
E
F
M
A
L
L
-
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
------
T
S
G
K
---
I
Y
F
D
E
K
D
V
T
E
L
------
P
P
K
D
R
N
V
G
L
V
F
Q
--
N
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
F
--------
P
--------
L
---------
E
L
R
KA----
P
--------
R
E
E
------
I
D
K
K
V
R
E
V
-
A
----
K
M
L
H
I
D
-
K
L
L
N
--------
R
Y
----
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
------------------------------------------------------------------------------------------------------------------------------------------
117
HHSearch
82.26
36%
-119
- C1 -
2YYZ
3
?
A:
[4-208]
-------
I
R
V
V
N
L
K
K
Y
--
F
GK--
V
------
K
A
------
V
D
G
-
V
S
F
E
V
K
D
G
E
F
V
A
L
L
-
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
Y
K
P
T
S
G
E
I
Y
F
D
D
V
---
L
V
N
D
I
------------
P
P
K
Y
R
E
V
G
M
V
F
Q
--
N
Y
A
L
Y
P
H
M
T
V
F
E
N
I
A
F
--------
P
--------
L
---------
R
--------
A
RRISKD
E
V
E
K
R
------
V
V
----
E
I
-
A
----
R
K
L
L
I
D
-
N
L
L
D
--------
R
K
----
P
T
Q
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
Q
Q
E
L
G
I
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
N
-----------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
81.66
35%
-130
- C1 -
1Z47
1
?
A:
[40-219]
------------------------------------------------
E
G
E
M
V
G
L
L
-
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
---
R
V
T
D
------
L
------
P
P
Q
K
R
N
V
G
L
V
F
Q
--
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
S
F
--------
G
--------
L
---------
R
E
K
RV----
P
--------
K
D
E
------
M
D
A
R
V
R
E
L
-
L
----
R
F
M
R
L
E
-
S
Y
A
N
--------
R
F
----
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
81.57
35%
-131
- C1 -
1Z47
1
?
B:
[40-219]
------------------------------------------------
E
G
E
M
V
G
L
L
-
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
---
R
V
T
D
------
L
------
P
P
Q
K
R
N
V
G
L
V
F
Q
--
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
S
F
--------
G
--------
L
---------
R
EKRV----
P
--------
K
D
E
------
M
D
A
R
V
R
E
L
-
L
----
R
F
M
R
L
E
-
S
Y
A
N
--------
R
F
----
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
------------------------------------------------------------------------------------------------------------------------------------------
118
HHSearch
81.41
33%
-120
- C1 -
3RLF
3
MALK_ECOLI
A:
[4-208]
-------
V
Q
L
Q
N
V
T
K
A
--
W
----
G
EV----
V
V
------
S
K
D
-
I
N
L
D
I
H
E
G
E
F
V
V
F
V
-
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
K
---
R
M
N
D
T
------------
P
P
A
E
R
G
V
G
M
V
F
Q
--
S
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
F
--------
G
--------
L
---------
K
--------
L
A
GAK
K
E
V
I
N
Q
R
------
V
N
----
Q
V
-
A
----
E
V
L
Q
L
A
-
H
L
L
D
--------
R
K
----
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
-----------------------------------------------------------------------------------------------------------------------------------------
113
HHSearch
81.32
35%
-119
- C1 -
1V43
-
?
A:
[13-223]
-------
V
K
L
E
N
L
T
K
R
--
F
----
G
NF----
T
A
------
V
N
K
-
L
N
L
T
I
K
D
G
E
F
L
V
L
L
-
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
Y
F
G
D
R
---
D
V
T
Y
L
------------
P
P
K
D
R
N
I
S
M
V
F
Q
--------
H
M
T
V
Y
E
N
I
A
F
--------
P
--------
L
-------------------KKFP
K
D
E
I
D
K
R
------
V
R
----
W
A
-
A
----
E
L
L
Q
I
E
-
E
L
L
N
--------
R
Y
----
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
L
K
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
-----------------------------------------------------------------------------------------------------------------------------------------
103
Fugue
81.20
33%
-110
- C1 -
1OXS
23
?
C:
[1-352]
-MVRII
V
K
N
V
-
S
K
V
F
K
KG
K
----
V
------
V
A
------
L
D
N
-
V
N
I
N
I
E
N
G
E
R
F
G
I
L
-
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
R
---
L
V
A
S
N
G
K
L
-
I
V
------
P
P
E
D
R
K
I
G
M
V
F
Q
--
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
A
F
--------
P
LTNMKMSK
E
---------
E
--------
I
--------
R
K
R
------
V
E
----
E
V
-
A
----
K
I
L
D
I
H
-
H
V
L
N
--------
H
F
----
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
KGKLVQVGKPEDLYDNPVSIQVASLIGEINELEGKVTNEGVVIGSLRFPVSVSSDRAIIGIRPEDVKLSKDVIKDDSWILVGKGKVKVIGYQGGLFRITITPLDSEEEIFTYSDHPIHSGEEVLVYVRKDKIKVFEK
53
PsiBlast_CBE
80.86
37%
-118
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[23-217]
---------------------------------------
I
S
-
L
S
L
D
P
G
E
--
I
L
F
I
I
-
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
-----
T
I
F
S
K
N
T
N
L
------
P
V
R
E
R
R
L
G
Y
L
V
Q
--
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
GLGNGKGR
T
--------
A
---------
Q
--------
E
--------
R
Q
R
------
I
E
----
A
M
-
L
----
E
L
T
G
I
S
-
E
L
A
G
--------
R
Y
----
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
------------------------------------------------------------------------------------------------------------------------------------------
116
HHSearch
80.31
34%
-115
- C1 -
1OXX
20
?
K:
[4-215]
-------
I
I
V
K
N
V
S
K
V
--
F
KKGK
V
------
V
A
------
L
D
N
-
V
N
I
N
I
E
N
G
E
R
F
G
I
L
-
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
R
---
L
V
A
S
N
G
K
-
L
I
V
------
P
P
E
D
R
K
I
G
M
V
F
Q
--
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
A
F
--------
P
--------
L
---------
T
--------
N
MKMSKEEI
R
K
R
------
V
E
----
E
V
-
A
----
K
I
L
D
I
H
-
H
V
L
N
--------
H
F
----
P
R
E
L
S
G
A
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
-----------------------------------------------------------------------------------------------------------------------------------------
111
HHSearch
80.09
35%
-118
- C1 -
3D31
-
?
A:
[1-202]
------
M
I
E
I
E
S
L
S
R
K
--
W
----
K
N-----
F
S
------
L
D
N
-
L
S
L
K
V
E
S
G
E
Y
F
V
I
L
-
G
P
T
G
A
G
K
T
L
F
L
E
L
I
A
G
F
H
V
P
D
S
G
R
I
L
L
D
G
K
---
D
V
T
D
L
------------
S
P
E
K
H
D
I
A
F
V
Y
Q
--
N
Y
S
L
F
P
H
M
N
V
K
K
N
L
E
F
--------
G
--------
M
---------
R
--------
M
K
KIKD---
P
K
R
------
V
L
----
D
T
-
A
----
R
D
L
K
I
E
-
H
L
L
D
--------
R
N
----
P
L
T
L
S
G
G
E
Q
Q
R
V
A
L
A
R
A
L
V
T
N
P
K
I
L
L
L
D
E
P
L
S
A
L
D
P
R
T
Q
E
N
A
R
E
M
L
S
V
L
H
K
K
N
K
L
T
V
L
H
I
T
H
D
Q
T
E
A
R
I
M
A
D
R
I
A
V
V
M
-----------------------------------------------------------------------------------------------------------------------------------------
52
PsiBlast_CBE
79.89
37%
-113
- C1 -
3FVQ
3
FBPC_NEIG1
B:
[23-212]
---------------------------------------
I
S
-
L
S
L
D
P
G
E
--
I
L
F
I
I
-
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
-----
T
I
F
S
K
N
T
N
L
------
P
V
R
E
R
R
L
G
Y
L
V
Q
--
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
Y
GLGNGKGR
T
--------
A
---------
Q
--------
E
--------
R
Q
R
------
I
E
----
A
M
-
L
----
E
L
T
G
I
S
-
E
L
A
G
--------
R
Y
----
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
------------------------------------------------------------------------------------------------------------------------------------------
115
HHSearch
78.57
30%
-119
- C1 -
3TUI
1
METN_ECOLI
C:
[24-238]
------
M
I
K
L
S
N
I
T
K
V
--
F
----
H
QGTRTI
Q
A
------
L
N
N
-
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
-
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
---
E
L
T
T
L
S
E
-
S
E
L
------
T
K
A
R
R
Q
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
--------
P
--------
L
---------
E
--------
L
DNTPKDEV
K
R
R
------
V
T
----
E
L
-
L
----
S
L
V
G
L
G
-
D
K
H
D
--------
S
Y
----
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
-----------------------------------------------------------------------------------------------------------------------------------------
92
PsiBlast_CBE
73.38
31%
-118
- C1 -
4MKI
4
ECFA2_CALS4
A:
[30-221]
---------------------------------------
I
N
-
F
S
I
D
D
E
E
--
F
V
G
I
I
-
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
G
I
---
D
I
T
D
--
K
K
V
S
L
------
K
D
I
R
K
Q
V
G
L
V
F
Q
YP
E
Y
Q
L
F
E
E
-
T
V
F
K
D
I
A
F
--------
G
--------
P
S
N
L
GLS
E
E
-
E
--------
V
--------
K
E
R
------
V
Y
----
E
A
-
M
----
E
I
V
G
I
S
K
E
L
A
D
--------
K
S
----
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
K
E
I
H
D
K
Y
K
M
I
T
I
L
V
S
H
N
M
E
D
I
A
R
I
A
D
K
I
I
V
M
------------------------------------------------------------------------------------------------------------------------------------------
91
PsiBlast_CBE
73.00
31%
-117
- C1 -
4MKI
4
ECFA2_CALS4
B:
[30-221]
---------------------------------------
I
N
-
F
S
I
D
D
E
E
--
F
V
G
I
I
-
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
G
I
---
D
I
T
D
--
K
K
V
S
L
------
K
D
I
R
K
Q
V
G
L
V
F
Q
YP
E
Y
Q
L
F
E
E
-
T
V
F
K
D
I
A
F
--------
G
--------
P
S
N
L
GLS
E
E
-
E
--------
V
--------
K
E
R
------
V
Y
----
E
A
-
M
----
E
I
V
G
I
S
K
E
L
A
D
--------
K
S
----
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
K
E
I
H
D
K
Y
K
M
I
T
I
L
V
S
H
N
M
E
D
I
A
R
I
A
D
K
I
I
V
M
------------------------------------------------------------------------------------------------------------------------------------------
68
PsiBlast_CBE
69.13
33%
-107
- C1 -
3C41
3
?
K:
[7-209]
--------------
H
Q
--
L
----
K
------
K
S
FGSLEV
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
-
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-----
I
N
L
K
A
K
D
T
N
L
------
N
K
V
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
--------
A
--------
P
---------
M
KVRKW---
P
--------
R
E
K
------
A
E
AKAM
E
L
-
L
----
D
K
V
G
L
K
-
D
K
A
H
--------
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
--------------------------------------------------------------------------------------------------------------------------------------------
77
PsiBlast_CBE
68.75
31%
-108
- C1 -
3TIF
7
Y796_METJA
A:
[19-204]
--------------
Y
A
--
L
----
K
------
N
-----------
V
N
L
N
I
K
E
G
E
F
V
S
I
M
-
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
---
K
T
N
D
L
D
D
D
E
L
T
------
K
I
R
R
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
PLIFKYR
G
A
--------
M
---------
S
--------
G
--------
E
E
R
------
R
K
----
R
A
-
L
----
E
C
L
K
M
A
-
E
L
E
E
--------
R
F
ANHK
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
---------------------------------------------------------------------------------------------------------------------------------------------------------
76
PsiBlast_CBE
68.12
31%
-103
- C1 -
3TIF
6
Y796_METJA
B:
[19-204]
--------------
Y
A
--
L
----
K
------
N
-----------
V
N
L
N
I
K
E
G
E
F
V
S
I
M
-
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
---
K
T
N
D
L
D
D
D
E
L
T
------
K
I
R
R
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
PLIFKYRG
A
--------
M
---------
S
--------
G
--------
E
E
R
------
R
K
----
R
A
-
L
----
E
C
L
K
M
A
-
E
L
E
E
--------
R
F
ANHK
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
---------------------------------------------------------------------------------------------------------------------------------------------------------
67
PsiBlast_CBE
68.05
32%
-99
- C1 -
2OLJ
4
?
A:
[22-230]
-------
L
Q
M
-
I
D
V
H
Q
--
L
----
K
------
K
S
FGSLEV
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
-
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-----
I
N
L
K
A
K
D
T
N
L
------
N
K
V
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
--------
A
--------
P
---------
M
KVRKW---
P
--------
R
E
K
------
A
E
A
K
A
M
E
L
-
L
----
D
K
V
G
L
K
-
D
K
A
H
--------
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
--------------------------------------------------------------------------------------------------------------------------------------------
62
PsiBlast_CBE
67.86
32%
-96
- C1 -
2OLK
1
?
D:
[22-230]
-------
L
Q
M
-
I
D
V
H
Q
--
L
----
K
------
K
S
FGSLEV
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
-
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-----
I
N
L
K
A
K
D
T
N
L
------
N
K
V
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
--------
A
--------
P
---------
M
KVRKW---
P
--------
R
E
K
------
A
E
AKAM
E
L
-
L
----
D
K
V
G
L
K
-
D
K
A
H
--------
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
--------------------------------------------------------------------------------------------------------------------------------------------
73
PsiBlast_CBE
67.68
31%
-111
- C1 -
4YMU
2
?
A:
[17-207]
------------------
L
----
K
------
G
V
------
T
L
K
-
V
N
----
K
G
E
V
V
V
I
I
-
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
---
K
I
N
N
G
K
V
N
I
N
-------
K
V
R
Q
K
-
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
--------
A
--------
P
---------
V
--------
K
--------
V
K
K
------
M
N
----
K
K
E
A
----
E
E
L
A
V
D
-
L
L
A
K
V
GLLDKKD
Q
Y
----
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
--------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
67.57
35%
-120
- C1 -
1VCI
1
?
A:
[30-219]
----------------------------------------
K
-
L
N
L
T
I
K
D
G
E
F
L
V
L
L
-
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
Y
F
G
D
R
---
D
V
T
------
Y
L
------
P
P
K
D
R
N
I
S
M
V
F
Q
--------
H
M
T
V
Y
E
N
I
A
F
--------
P
--------
L
----------KKF-----
P
--------
K
D
E
------
I
D
----
K
R
-
V
R
W
A
A
E
L
L
Q
I
E
-
E
L
L
N
--------
R
Y
----
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
L
K
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
---------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
67.52
36%
-114
- C1 -
2D62
6
?
A:
[39-213]
---------------------------------------------------------
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
R
G
Q
I
Y
I
E
D
N
---
L
V
A
D
P
E
K
G
V
F
V
------
P
P
K
E
R
D
V
A
M
V
F
Q
--
S
Y
A
L
Y
P
H
M
T
V
Y
D
N
I
A
F
--------
P
--------
L
---------
K
L
R
KV----
P
--------
K
Q
E
------
I
D
----
K
R
-
V
R
E
V
A
E
M
L
G
L
T
-
E
L
L
N
--------
R
K
----
P
R
E
L
S
G
G
Q
R
Q
R
V
A
L
G
R
A
I
I
R
R
P
K
V
F
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
K
M
R
A
E
L
K
K
L
Q
R
Q
L
G
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
---------------------------------------------------------------------------------------------------------------------------------------------
63
PsiBlast_CBE
67.26
32%
-94
* C1 *
2OLK
1
?
C:
[22-230]
-------
L
Q
M
-
I
D
V
H
Q
--
L
----
K
------
K
S
FGSLEV
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
-
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-----
I
N
L
K
A
K
D
T
N
L
------
N
K
V
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
--------
A
--------
P
---------
M
KVRKW---
P
--------
R
E
K
------
A
E
AKAM
E
L
-
L
----
D
K
V
G
L
K
-
D
K
A
H
--------
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
--------------------------------------------------------------------------------------------------------------------------------------------
64
PsiBlast_CBE
67.03
32%
-94
- C1 -
2OLK
2
?
B:
[22-230]
-------
L
Q
M
-
I
D
V
H
Q
--
L
----
K
------
K
S
FGSLEV
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
-
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-----
I
N
L
K
A
K
D
T
N
L
------
N
K
V
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
--------
A
--------
P
---------
M
KVRKW---
P
--------
R
E
K
------
A
E
AKAM
E
L
-
L
----
D
K
V
G
L
K
-
D
K
A
H
--------
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
--------------------------------------------------------------------------------------------------------------------------------------------
71
PsiBlast_CBE
66.98
31%
-103
- C1 -
4YMV
1
?
A:
[17-207]
------------------
L
----
K
------
G
V
------
T
L
K
-
V
N
----
K
G
E
V
V
V
I
I
-
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
---
K
I
N
N
G
K
V
N
I
N
-------
K
V
R
Q
K
-
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
--------
A
--------
P
---------
V
--------
K
--------
V
K
K
------
M
N
----
K
K
E
A
----
E
E
L
A
V
D
-
L
L
A
K
V
GLLDKKD
Q
Y
----
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
--------------------------------------------------------------------------------------------------------------------------------------------
69
PsiBlast_CBE
66.61
33%
-104
- C1 -
3C41
3
?
J:
[7-209]
--------------
H
Q
--
L
----
K
------
K
S
FGSLEV
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
-
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-----
I
N
L
K
A
K
D
T
N
L
------
N
K
V
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
--------
A
--------
P
---------
M
KVRKW---
P
--------
R
E
K
------
A
E
AKAM
E
L
-
L
----
D
K
V
G
L
K
-
D
K
A
H
--------
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
--------------------------------------------------------------------------------------------------------------------------------------------
66
PsiBlast_CBE
66.51
32%
-93
- C1 -
2OLJ
3
?
B:
[22-230]
-------
L
Q
M
-
I
D
V
H
Q
--
L
----
K
------
K
S
FGSLEV
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
-
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-----
I
N
L
K
A
K
D
T
N
L
------
N
K
V
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
--------
A
--------
P
---------
M
KVRKW---
P
--------
R
E
K
------
A
E
AKAM
E
L
-
L
----
D
K
V
G
L
K
-
D
K
A
H
--------
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
--------------------------------------------------------------------------------------------------------------------------------------------
57
PsiBlast_CBE
66.50
32%
-98
- C1 -
2Q0H
4
?
A:
[23-230]
--------
Q
M
-
I
D
V
H
Q
--
L
----
K
------
K
S
FGSLEV
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
-
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-----
I
N
L
K
A
K
D
T
N
L
------
N
K
V
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
--------
A
--------
P
---------
M
K
V
RKW---
P
--------
R
E
K
------
A
E
A
K
A
M
E
L
-
L
----
D
K
V
G
L
K
-
D
K
A
H
--------
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
--------------------------------------------------------------------------------------------------------------------------------------------
72
PsiBlast_CBE
66.08
31%
-107
- C1 -
4YMU
2
?
J:
[17-207]
------------------
L
----
K
------
G
V
------
T
L
K
-
V
N
----
K
G
E
V
V
V
I
I
-
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
---
K
I
N
N
G
K
V
N
I
N
-------
K
V
R
Q
K
-
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
--------
A
--------
P
---------
V
--------
K
--------
V
K
K
------
M
N
----
K
K
E
A
----
E
E
L
A
V
D
-
L
L
A
K
VGLLDKKD
Q
Y
----
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
--------------------------------------------------------------------------------------------------------------------------------------------
75
PsiBlast_CBE
65.97
31%
-105
- C1 -
1L2T
4
Y796_METJA
A:
[19-204]
--------------
Y
A
--
L
----
K
------
N
-----------
V
N
L
N
I
K
E
G
E
F
V
S
I
M
-
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
---
K
T
N
D
L
D
D
D
E
L
T
------
K
I
R
R
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
PLIFKYR
G
A
--------
M
---------
S
--------
G
--------
E
E
R
------
R
K
----
R
A
-
L
----
E
C
L
K
M
A
-
E
L
E
E
--------
R
F
ANHK
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
---------------------------------------------------------------------------------------------------------------------------------------------------------
65
PsiBlast_CBE
65.72
32%
-94
- C1 -
2OLK
1
?
A:
[22-230]
-------
L
Q
M
-
I
D
V
H
Q
--
L
----
K
------
K
S
FGSLEV
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
-
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-----
I
N
L
K
A
K
D
T
N
L
------
N
K
V
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
--------
A
--------
P
---------
M
KVRKW---
P
--------
R
E
K
------
A
E
A
K
A
M
E
L
-
L
----
D
K
V
G
L
K
-
D
K
A
H
--------
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
--------------------------------------------------------------------------------------------------------------------------------------------
74
PsiBlast_CBE
65.65
31%
-101
- C1 -
1L2T
4
Y796_METJA
B:
[19-204]
--------------
Y
A
--
L
----
K
------
N
-----------
V
N
L
N
I
K
E
G
E
F
V
S
I
M
-
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
---
K
T
N
D
L
D
D
D
E
L
T
------
K
I
R
R
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
PLIFKYRG
A
--------
M
---------
S
--------
G
--------
E
E
R
------
R
K
----
R
A
-
L
----
E
C
L
K
M
A
-
E
L
E
E
--------
R
F
ANHK
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
---------------------------------------------------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
65.43
32%
-97
- C1 -
3C4J
4
?
B:
[22-230]
-------
L
Q
M
-
I
D
V
H
Q
--
L
----
K
------
K
S
FGSLEV
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
-
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-----
I
N
L
K
A
K
D
T
N
L
------
N
K
V
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
--------
A
--------
P
---------
M
KVRKW---
P
--------
R
E
K
------
A
E
AKAM
E
L
-
L
----
D
K
V
G
L
K
-
D
K
A
H
--------
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
--------------------------------------------------------------------------------------------------------------------------------------------
70
PsiBlast_CBE
65.20
31%
-105
- C1 -
4YMV
1
?
J:
[17-207]
------------------
L
----
K
------
G
V
------
T
L
K
-
V
N
----
K
G
E
V
V
V
I
I
-
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
---
K
I
N
N
G
K
V
N
I
N
-------
K
V
R
Q
K
-
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
--------
A
--------
P
---------
V
--------
K
--------
V
K
K
------
M
N
----
K
K
E
A
----
E
E
L
A
V
D
-
L
L
A
K
VGLLDKKD
Q
Y
----
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
--------------------------------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
64.92
32%
-90
- C1 -
3C4J
3
?
A:
[22-230]
-------
L
Q
M
-
I
D
V
H
Q
--
L
----
K
------
K
S
FGSLEV
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
-
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
-----
I
N
L
K
A
K
D
T
N
L
------
N
K
V
R
E
E
V
G
M
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
--------
A
--------
P
---------
M
K
V
RKW---
P
--------
R
E
K
------
A
E
A
K
A
M
E
L
-
L
----
D
K
V
G
L
K
-
D
K
A
H
--------
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
G
-
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
--------------------------------------------------------------------------------------------------------------------------------------------
97
PsiBlast_CBE
54.29
31%
-102
- C1 -
1B0U
4
HISP_SALTY
A:
[45-224]
---------------------------------------------------------------
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
Q
NI
N
L
V
R
D
K
D
G
Q
L
K
V
AD
K
N
Q
L
R
L
L
R
T
R
L
T
M
V
F
Q
--
H
F
N
L
W
S
H
M
T
V
L
E
N
V
----------
M
--------
E
---------
A
--------
P
IQVLGL--
S
K
H
D
A
R
E
R
A
L
K
----
Y
L
-
A
----
K
V
G
I
D
E
-
R
A
Q
G
--------
K
Y
----
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
E
E
G
K
T
-
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
--------------------------------------------------------------------------------------------------------------------------------------------
90
PsiBlast_CBE
54.15
32%
-95
- C1 -
4U00
3
?
A:
[37-209]
---------------------------------------------------------
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
---
S
V
K
D
D
R
A
L
R
E
I
------
R
---
R
E
V
G
M
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
--------
A
--------
P
M
R
V
RRWP
R
E
K
--------
A
--------
E
K
K
------
A
L
----
E
L
-
L
----
E
R
V
G
I
L
-
D
Q
A
R
--------
K
Y
----
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
-
V
M
R
D
L
A
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
--------------------------------------------------------------------------------------------------------------------------------------------