@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0264: (2016-03-13 )
MKRNKTALRILVTLAVVLAITFWVGMSSKEVQAAVIEHPTPINEIFTDPVLTDNVKTLLGKADVTDEVTQTDLDSVTHLSAKSAGITTIEGLQYLTNLSELELIDNQVTDLNPLTNLTKITELRLSGNPLKDVSALAGLKNLKTMDLIYTDITDVTPLAGLSNLQVLNLDINQITDITPLAGLSNLQFLSFGSTQVSDLTPLANLSKLTTLNAMNSKVSDVSPLTGLSNLTEVYLEENQISDVSPLAKLPNLSIVTLTNQTITNQPVFYQNKPIVPNVVTGLSGELIAPDTISDNGTYTSPNLTWDLNSFINSVSYTFNQSVTFKNTTAPFSGTVTQPLTEVYAVVFDVDGEQTSAMVGVNELINEPTAPAKEGYIFDGWYDAKTDGNKWDFGIDKMPASDITLYAKFTENEEPNASSPINVEPNDNNSDNAEPNASSSNNVQENGTNEGINNLNSSGEDKVNIKLPITGDKLNVLPIFVGAVLIGIGLVLFRKKRQTK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.----------------------......120.......130.......140.......150.......160.......170.......180..----------------------.....190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340---.......350......----.360.......370.......380.......390--.......400.......410.......420.......430.......440.......450.......460.......470.......480......----.490.......--------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKR
N
K
T
A
L
R
I
L
V
T
L
A
V
V
L
A
I
T
F
W
VGMSSK
E
V
Q
A
A
VIEHPT
P
I
N
E
IFTDPVLTD
N
V
K
T
L
LGKADVTD
E
V
T
Q
T
D
L
D
S
V
T
H
LSAKSAGI
T
T
I
E
G
L
Q
Y
L
T
N
L
S
E
L
E
L
IDNQVTDLNP----------------------LTNL
T
K
I
T
E
L
R
LSGNP
L
K
D
V
S
A
L
AGLKNL
K
T
M
D
L
I
Y
TDITDVTPLAGLSN
L
Q
V
L
N
L
DINQITDITPLAGLS----------------------N
L
Q
F
L
SFGSTQVSDLTPLA
N
L
S
K
L
T
T
L
N
AMNSKVSDVSPLT
G
L
S
N
L
T
E
V
Y
L
EENQISDV
S
P
L
AKLPN
L
S
I
V
T
LTNQTITNQP
V
F
YQNKPIV
P
N
V
V
TGLSGELIAPDTISDNGTYTSP
N
L
T
W
D
L
N
S
F
I
N
S
V
S
Y
T
FNQ
S
V
T
FKNTTAPFSGTVT
Q
P
L
T
E
V
---
Y
A
V
V
F
DVDGE
Q
T
S
A
M
V
----
G
V
N
E
L
INEPTAPAKE
G
Y
I
F
D
G
W
YDAKTDGNKWDF--GIDKMPAS
D
I
T
L
Y
A
K
FTENEEPNASSP
I
N
VEPNDNNSDNAEPNASSSNNVQENGTNEGINNLNSSGE
D
K
V
N
I
K
L
PITGDK
L
N
V
L
P
I
F
V
G
A
V
L
I
G
I
G
----
L
V
L
F
R
KKRQTK--------------------------------------------------------------------------
67
HHSearch
83.67
73%
-121
- C5 -
1H6U
-
?
A:
[38-343]
-----------------------------------
I
T
Q
P
T
A
I
N
V
I
F
P
D
P
A
L
A
N
A
I
K
I
A
A
G
K
S
N
V
T
D
T
V
T
Q
A
D
L
D
G
I
T
T
L
S
A
F
G
T
G
V
T
T
I
E
G
V
Q
Y
L
N
N
L
I
G
L
E
L
K
D
N
Q
I
T
D
L
A
P
----------------------
L
K
N
L
T
K
I
T
E
L
E
L
S
G
N
P
L
K
N
V
S
A
I
A
G
L
Q
S
I
K
T
L
D
L
T
S
T
Q
I
T
D
V
T
P
L
A
G
L
S
N
L
Q
V
L
Y
L
D
L
N
Q
I
T
N
I
S
P
L
A
G
L
T
----------------------
N
L
Q
Y
L
S
I
G
N
A
Q
V
S
D
L
T
P
L
A
N
L
S
K
L
T
T
L
K
A
D
D
N
K
I
S
D
I
S
P
L
A
S
L
P
N
L
I
E
V
H
L
K
N
N
Q
I
S
D
V
S
P
L
A
N
T
S
N
L
F
I
V
T
L
T
N
Q
T
I
T
N
Q
P
V
F
Y
N
N
N
L
V
V
P
N
V
V
K
G
P
S
G
A
P
I
A
P
A
T
I
S
D
N
G
T
Y
A
S
P
N
L
T
W
N
L
T
S
F
I
N
N
V
S
Y
T
F
N
Q
S
V
T
F
K
N
T
T
V
P
F
S
G
T
V
T
Q
P
L
T
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
83.63
73%
-121
- C5 -
1H6U
-
?
A:
[38-343]
-----------------------------------
I
T
Q
P
T
A
I
N
V
I
F
P
D
P
A
L
A
N
A
I
K
I
A
A
G
K
S
N
V
T
D
T
V
T
Q
A
D
L
D
G
I
T
T
L
S
A
F
G
T
G
V
T
T
I
E
G
V
Q
Y
L
N
N
L
I
G
L
E
L
K
D
N
Q
I
T
D
L
A
P
----------------------
L
K
N
L
T
K
I
T
E
L
E
L
S
G
N
P
L
K
N
V
S
A
I
A
G
L
Q
S
I
K
T
L
D
L
T
S
T
Q
I
T
D
V
T
P
L
A
G
L
S
N
L
Q
V
L
Y
L
D
L
N
Q
I
T
N
I
S
P
L
A
G
L
T
----------------------
N
L
Q
Y
L
S
I
G
N
A
Q
V
S
D
L
T
P
L
A
N
L
S
K
L
T
T
L
K
A
D
D
N
K
I
S
D
I
S
P
L
A
S
L
P
N
L
I
E
V
H
L
K
N
N
Q
I
S
D
V
S
P
L
A
N
T
S
N
L
F
I
V
T
L
T
N
Q
T
I
T
N
Q
P
V
F
Y
N
N
N
L
V
V
P
N
V
V
K
G
P
S
G
A
P
I
A
P
A
T
I
S
D
N
G
T
Y
A
S
P
N
L
T
W
N
L
T
S
F
I
N
N
V
S
Y
T
F
N
Q
S
V
T
F
K
N
T
T
V
P
F
S
G
T
V
T
Q
P
L
T
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
88
Fugue
73.98
32%
-75
- C5 -
1M9S
8
INLB_LISMO
A:
[3-596]
---------------------------------
E
T
I
T
V
S
T
P
I
K
Q
I
F
P
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
----------------------
L
T
N
L
K
N
L
G
W
L
F
L
D
E
N
K
I
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
----------------------
K
L
D
T
L
S
L
E
----------------------
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
E
T
T
EKT
V
N
L
T
R
Y
V
K
Y
I
R
G
N
A
G
I
Y
KLP
R
E
D
N
S
L
K
Q
G
T
L
A
S
H
R
C
K
A
L
T
V
D
R
E
A
R
N
G
G
K
L
W
Y
R
L
K
N
I
G
W
T
K
A
E
N
L
S
L
D
R
Y
D
K
M
E
Y
D
K
G
V
T
A
Y
A
R
V
R
N
A
S
G
N
S
V
W
T
K
P
Y
N
T
A
G
A
--------
K
H
V
N
K
L
S
V
Y
Q
G
K
N
M
R
I
L
R
E
A
K
T
P
I
T
T
W
Y
Q
F
S
I
G
G
K
V
I
G
W
V
DTRA
L
N
T
F
Y
K
Q
S
M
E
K
P
T
R
L
T
R
Y
V
S
ANKAGESYYKVPVADNPVKRGTLAKYKN
Q
K
L
I
V
D
C
Q
A
T
I
EG
Q
L
W
Y
R
I
R
T
SS
T
F
I
G
W
T
K
AANLRAQ
22
PsiBlast_CBE
72.10
41%
-116
- C5 -
4AW4
9
INLB_LISMO
B:
[9-310]
--------------------------------------
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
L
T
S
L
N
L
S
N
N
Q
I
T
D
I
S
P
----------------------
I
Q
Y
L
P
N
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
----------------------
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
71.94
41%
-114
- C5 -
4AW4
6
INLB_LISMO
C:
[9-310]
--------------------------------------
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
L
T
S
L
N
L
S
N
N
Q
I
T
D
I
S
P
----------------------
I
Q
Y
L
P
N
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
----------------------
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69
HHSearch
71.16
43%
-118
- C5 -
1O6V
1
INLA_LISMO
A:
[174-465]
----------------------------------------------------------------------
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
LGILTNLDELSLNGNQLKDIGT
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
E
D
I
S
P
I
S
N
L
K
----------------------
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
70.57
41%
-115
- C5 -
4AW4
14
INLB_LISMO
A:
[9-310]
--------------------------------------
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
L
T
S
L
N
L
S
N
N
Q
I
T
D
I
S
P
----------------------
I
Q
Y
L
P
N
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
----------------------
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
------
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
69.93
38%
-113
- C5 -
2WQW
5
INLB_LISMO
A:
[6-286]
--------------------------------------
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
--------------------------------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
----------------------
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
C
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
C
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
A
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
69.68
38%
-114
- C5 -
2WQW
7
INLB_LISMO
B:
[6-286]
--------------------------------------
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
--------------------------------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
----------------------
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
C
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
C
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
A
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
68.64
38%
-115
- C5 -
2WQU
7
INLB_LISMO
A:
[9-288]
--------------------------------------
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
--------------------------------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
----------------------
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
68.63
38%
-113
- C5 -
2WQU
5
INLB_LISMO
E:
[9-288]
--------------------------------------
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
--------------------------------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
----------------------
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
68.10
42%
-110
- C5 -
1O6V
1
INLA_LISMO
A:
[167-464]
---------------------------------------------------------------
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
----------------------
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
ALT
N
L
E
LNENQLEDISPISNLK
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
67.96
69%
-128
- C5 -
4FHO
1
?
A:
[6-231]
--------------------------------
A
E
S
I
A
Q
P
T
P
I
N
V
I
F
P
D
P
A
L
A
N
A
V
K
T
A
T
G
K
S
N
V
T
D
A
V
T
Q
A
D
L
D
G
I
A
T
L
S
A
F
N
T
G
V
T
T
I
E
G
I
Q
Y
L
N
N
L
I
G
L
E
L
K
D
N
Q
I
T
D
L
T
P
----------------------
L
K
N
L
T
K
I
T
E
L
E
L
S
G
N
P
L
K
N
V
S
A
I
A
G
L
Q
S
I
K
T
L
D
L
T
S
T
Q
I
T
D
V
T
P
L
A
G
L
S
N
L
Q
V
L
Y
L
D
L
N
Q
I
T
N
I
S
P
L
A
G
L
T
----------------------
N
L
Q
Y
L
S
I
G
N
N
Q
V
N
D
L
T
P
L
A
N
L
S
K
L
T
T
L
R
A
D
D
N
K
I
S
D
I
S
P
L
A
S
L
P
N
L
I
E
V
H
L
K
D
N
Q
I
S
D
V
S
P
L
A
N
L
S
N
L
F
I
V
T
L
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
67.93
42%
-111
- C5 -
2OMV
1
INLA_LISMO
A:
[162-459]
---------------------------------------------------------------
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
----------------------
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
ALT
N
L
E
LNENQLEDISPISNLK
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
S
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
67.85
42%
-110
- C5 -
2OMT
2
INLA_LISMO
A:
[163-460]
---------------------------------------------------------------
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
----------------------
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
ALT
N
L
E
LNENQLEDISPISNLK
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
67.61
42%
-110
- C5 -
2OMY
4
INLA_LISMO
A:
[162-459]
---------------------------------------------------------------
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
----------------------
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
ALT
N
L
E
LNENQLEDISPISNLK
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
67.45
42%
-113
- C5 -
1O6V
1
INLA_LISMO
B:
[167-464]
---------------------------------------------------------------
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
----------------------
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
ALT
N
L
E
LNENQLEDISPISNLK
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
87
Fugue
67.42
41%
-103
- C5 -
1H6T
-
INLB_LISMO
A:
[31-321]
----------------------------
G
P
L
G
S
E
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
----------------------
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
----------------------
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
----------------------
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
67.36
38%
-115
- C5 -
2WQU
6
INLB_LISMO
F:
[9-288]
--------------------------------------
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
--------------------------------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
----------------------
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
67.35
42%
-109
- C5 -
2OMW
3
INLA_LISMO
A:
[162-459]
---------------------------------------------------------------
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
----------------------
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
ALT
N
L
E
LNENQLEDISPISNLK
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
S
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------