@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2847: (2016-04-08 )
MTKDIMDAVFIKEMAKTTSNLYRLGWDERNGGNITYLLDEKEVAEYLDVKQIIRTIPMDFDGKKLAGKYFLVTGSGKYFKNVEEAPAVNLGVIQVSEDGKAVHLLWGYTDGGLPTSELPAHFMSHIARLSVDPENRVVMHCHATHLLAMTFTHELTERAFTRTLWQMCTECLVVFPEGVGIIPWLVPGTNEIGEATSEKMKENRLIVWPHHGIYGAGQSMDETFGLIETAEKAAEVYTIVMSQGGIKQAITDEQLKALGERFGVEAKAGYLNN
Atome Classification :
(23 SA)
.........10........20........30........40.......-.50........60........70........80........90........100.......110.......120.......-130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
T
K
D
I
M
D
A
V
F
I
K
E
M
A
K
T
T
S
N
L
Y
RLGWDERNGG
N
I
T
Y
L
L
D
E
K
E
V
A
E
Y
L
D
-
V
K
Q
I
I
R
TIPMDFDG
K
K
LA
G
K
Y
F
L
V
TGS
G
K
Y
F
K
NVEEAPAV
N
L
G
V
I
Q
VSEDG
K
A
V
H
L
L
W
GYTDGGL
P
T
S
E
L
P
A
H
F
M
S
H
I
A
R
L-SVDPEN
R
V
V
M
H
CHA
T
H
L
L
A
M
T
F
T
H
E
L
T
E
R
A
F
T
R
T
L
W
Q
M
C
T
E
C
L
V
VFPEGV
G
I
I
P
W
LVPG
T
N
E
I
G
E
A
T
S
E
K
M
KEN
R
L
I
V
WPHHGIYGAGQ
S
M
D
E
T
F
G
L
I
E
T
A
E
K
A
A
E
V
Y
T
I
V
MSQGGIKQAI
T
D
E
Q
L
K
A
L
G
E
RFGVEAKAGYLNN
49
PsiBlast_CBE
98.49
51%
-109
- C4 -
2V9G
4
RHAD_ECOLI
C:
[2-272]
--
Q
N
I
T
Y
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
W
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
50
PsiBlast_CBE
98.22
51%
-112
- C4 -
2V9G
4
RHAD_ECOLI
B:
[2-272]
--
Q
N
I
T
Y
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
W
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
48
PsiBlast_CBE
98.14
51%
-107
- C4 -
2V9G
4
RHAD_ECOLI
D:
[2-272]
--
Q
N
I
T
Y
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
W
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
40
PsiBlast_CBE
98.12
51%
-112
- C4 -
2V9N
7
RHAD_ECOLI
D:
[2-272]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
F
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
42
PsiBlast_CBE
97.90
51%
-111
- C4 -
2V9N
9
RHAD_ECOLI
B:
[2-272]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
F
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
3
PsiBlast_PDB
97.89
51%
-115
- C4 -
2UYU
2
RHAD_ECOLI
A:
[2-272]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
F
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
41
PsiBlast_CBE
97.73
51%
-111
- C4 -
2V9N
10
RHAD_ECOLI
C:
[2-272]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
F
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
51
PsiBlast_CBE
97.68
50%
-111
- C4 -
2V9E
8
RHAD_ECOLI
B:
[2-273]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
W
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
S
-
43
PsiBlast_CBE
97.68
51%
-115
- C4 -
2UYU
3
RHAD_ECOLI
E:
[2-272]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
F
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
54
PsiBlast_CBE
97.62
50%
-111
- C4 -
2V9M
6
RHAD_ECOLI
B:
[2-272]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
M
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
F
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
2
PsiBlast_PDB
97.54
51%
-109
- C4 -
1OJR
8
RHAD_ECOLI
A:
[2-272]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
4
PsiBlast_PDB
97.51
51%
-112
- C4 -
2V9N
7
RHAD_ECOLI
A:
[2-272]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
F
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
7
PsiBlast_PDB
97.41
51%
-109
- C4 -
2V9G
2
RHAD_ECOLI
A:
[2-272]
--
Q
N
I
T
Y
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
W
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
46
PsiBlast_CBE
97.37
51%
-110
- C4 -
2UYV
4
RHAD_ECOLI
C:
[2-272]
--
Q
N
I
T
Y
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
45
PsiBlast_CBE
97.19
51%
-111
- C4 -
2UYV
4
RHAD_ECOLI
D:
[2-272]
--
Q
N
I
T
Y
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
21
PsiBlast_CBE
97.08
51%
-112
- C4 -
1GT7
47
RHAD_ECOLI
T:
[2-272]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
E
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
1
PsiBlast_PDB
97.05
51%
-110
- C4 -
1GT7
-
RHAD_ECOLI
A:
[2-272]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
E
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
6
PsiBlast_PDB
97.02
51%
-111
- C4 -
2UYV
3
RHAD_ECOLI
A:
[2-272]
--
Q
N
I
T
Y
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
44
PsiBlast_CBE
97.01
51%
-113
- C4 -
2V29
8
RHAD_ECOLI
B:
[2-272]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
W
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
E
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
8
PsiBlast_PDB
97.01
50%
-110
- C4 -
2V9E
8
RHAD_ECOLI
A:
[2-273]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
W
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
S
-
11
PsiBlast_PDB
96.86
50%
-109
- C4 -
2V2A
3
RHAD_ECOLI
A:
[2-272]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
G
Q
T
I
S
A
A
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
5
PsiBlast_PDB
96.80
51%
-112
- C4 -
2V29
8
RHAD_ECOLI
A:
[2-272]
--
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
W
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
E
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--
47
PsiBlast_CBE
96.17
51%
-110
- C4 -
2UYV
3
RHAD_ECOLI
B:
[2-272]
--
Q
N
I
T
Y
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
--