@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1039: (2015-12-05 )
MSYIEMKHSYKRYQTGETEIVANNDISFSIERGELVVILGASGAGKSTVLNILGGMDSNSEGEVLIDGKNIANYTIRELTRYRRYDVGFVFQFYNLVPNLTALENVELASEIVPKALDAQQALENVGLGHRINHFPAQLSGGEQQRVAIARAIAKKPKLLLCDEPTGALDYQTGKQVLAILQKMAQSKETTVIIVTHNTALAPIANRVIHMHDSKISDIVINENPSDIQNIEY
Atome Classification :
(20 SA)
-.........10........20........30........40........50........60........70---------..-......80........90........100.....--.-----------.-----110-----.-----.-----.....120--.-------..---.....130.-.-......140.......150.......160.......170.......180.......190.....-.-.200.-.-......210......----.----220.......230.----------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-M
S
Y
I
E
M
K
HS
Y
K
RYQTGE
T
E
I
V
ANN
D
I
S
F
S
I
ERG
E
L
V
V
I
LGASGAG
K
S
T
V
L
N
I
LGGMDSNSEG
E
V
L
I
DGKNI---------
A
N
-
Y
T
I
R
E
L
T
R
Y
R
RYD
V
G
F
V
F
Q
F
Y
N
LVPN
L
T
A
L
E
N
V
E
--
L
-----------
A
-----
S
E
I
-----
V
-----
P
-----
K
AL
D
A
Q
Q
---
A
-------
L
E
---NVGLGH-RI-N-HFPAQLSGG
E
Q
Q
R
V
A
I
A
R
A
I
AKKP
K
L
L
L
CDEPTGAL
D
Y
Q
T
G
K
Q
V
L
A
I
L
Q
K
M
AQSKE
T
T
V
I
I
V
TH-N-T
A
L
-
A
-
P
-
I
A
N
R
V
I
H
MHDSKI
S
D
----
I
----
V
INENPSDIQNIEY----------------------------------------------------------------------------------------------------------------
121
HHSearch
95.28
42%
-104
- C1 -
3TIF
7
Y796_METJA
A:
[1-230]
---
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
D
-
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
--
L
-----------
P
-----
L
I
F
-----
K
YR
G
A
M
S
G
E
E
--
R
R
K
R
A
L
E
---
C
-------
L
K
---
M
A
E
L
E
E
R
F
A
-
N
-
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
-
D
-
I
N
V
-
A
-
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
----
E
----
E
K
L
R
--------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
93.09
44%
-105
- C1 -
1F3O
2
Y796_METJA
A:
[2-223]
----
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
D
-
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
--
L
P
L
I
F
K
YRG---
A
-----
M
S
G
-----
E
-----
E
-----
R
R
K
R
A
L
E
---
C
-------
L
K
---
M
A
E
L
E
E
-
R
F
A
N
-
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
E
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
-
D
-
I
N
V
-
A
-
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
----
E
----
E
K
L
R
G
F
------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
91.68
44%
-111
- C1 -
1L2T
4
Y796_METJA
A:
[2-223]
----
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
D
-
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
--
L
PLIFKYR
G
A
M
S
G
-----
E
E
R
-----
R
-----
K
-----
R
A
L
E
C
L
K
---
M
-------
A
E
------
L
E
E
-
R
F
A
N
-
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
-
D
-
I
N
V
-
A
-
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
----
E
----
E
K
L
R
--------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
90.89
44%
-112
- C1 -
1L2T
4
Y796_METJA
B:
[2-223]
----
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
D
-
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
--
L
PLIFKYRGAMS
G
-----
E
E
R
-----
R
-----
K
-----
R
A
L
E
C
L
K
---
M
-------
A
E
------
L
E
E
-
R
F
A
N
-
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
-
D
-
I
N
V
-
A
-
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
----
E
----
E
K
L
R
G
F
------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
90.60
43%
-110
- C1 -
3TIF
7
Y796_METJA
A:
[2-223]
----
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
D
-
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
--
L
PLIFKYR
G
A
M
S
G
-----
E
E
R
-----
R
-----
K
-----
R
A
L
E
C
L
K
---
M
-------
A
E
------
L
E
E
-
R
F
A
N
-
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
-
D
-
I
N
V
-
A
-
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
----
E
----
E
K
L
R
--------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
89.21
43%
-115
- C1 -
3TIF
7
Y796_METJA
B:
[2-223]
----
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
D
-
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
--
L
PLIFKYRGAMS
G
-----
E
E
R
-----
R
-----
K
-----
R
A
L
E
C
L
K
---
M
-------
A
E
------
L
E
E
-
R
F
A
N
-
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
-
D
-
I
N
V
-
A
-
R
-
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
----
E
----
E
K
L
R
G
F
------------------------------------------------------------------------------------------------------------------------
120
HHSearch
83.66
41%
-106
- C1 -
2PCJ
-
LOLD_AQUAE
A:
[2-222]
-
A
E
I
L
R
A
E
N
I
K
K
V
I
R
G
----
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
---------
D
Y
-
T
N
E
K
E
L
S
L
L
R
N
R
K
L
G
F
V
F
Q
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
I
--
V
-----------
P
-----
M
L
K
-----
M
-----
G
KP
K
K
E
A
K
E
R
G
E
Y
---
L
-------
L
S
---
E
L
G
L
G
D
-
K
L
-
S
-
R
K
P
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
-
E
G
G
T
S
I
V
M
V
T
H
-
E
-
R
E
L
-
A
-
E
-
L
T
H
R
T
L
E
M
K
D
G
K
V
V
G
----
E
----
I
T
R
V
--------------------------------------------------------------------------------------------------------------------------
128
Fugue
81.61
32%
-107
- C1 -
1Z47
1
?
A:
[11-355]
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
G
G
A
R
S
V
R
---
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
---------
T
D
-
L
P
P
Q
K
R
------
N
V
G
L
V
F
Q
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
S
--
F
-----------
G
-----
L
R
E
K
RVP
K
D
-----
E
-----
M
D
A
R
V
R
E
---
L
-------
L
R
---
F
M
R
L
E
S
-
Y
A
-
N
-
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
-
E
E
A
-
L
-
E
-
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
----
F
G
T
P
E
E
V
Y
E
K
P
G
T
L
F
V
A
S
F
IGE
S
N
V
W
T
R
A
V
Q
NG
R
I
E
V
AG
A
A
L
P
V
DPAVSEG
S
E
V
A
V
V
V
R
PKD
V
E
L
Q
P
A
S
EREAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R--
113
HHSearch
80.30
35%
-98
- C1 -
1OXX
21
?
K:
[1-228]
-
M
V
R
I
I
V
K
N
V
S
K
V
F
K
K
G
--
K
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
R
L
V
---------
A
S
-
N
G
K
L
I
V
-
P
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
A
--
F
-----------
P
-----
L
T
N
-----
M
-----
K
MSKEE
I
R
K
R
V
E
E
---
V
-------
A
K
---
I
L
D
I
H
H
-
V
L
-
N
-
H
F
P
R
E
L
S
G
A
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
-
D
-
P
A
D
I
F
-
A
-
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
----
V
----
G
K
P
E
D
L
Y
D
N
P
V
S
I
Q
----------------------------------------------------------------------------------------------------------------
126
Fugue
78.99
35%
-101
- C1 -
1OXS
23
?
C:
[1-352]
-
M
V
R
I
I
V
K
N
V
S
K
V
F
K
K
G
K
V
V
A
L
D
N
--
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
R
L
V
---------
A
S
-
N
G
K
L
I
V
P
P
E
D
R
-
K
I
G
M
V
F
Q
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
A
--
F
-----------
P
LTNMK
M
S
K
-----
E
-----
E
-----
I
R
K
R
V
E
E
---
V
-------
A
K
---
I
L
D
I
H
H
-
V
L
-
N
-
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
-
D
-
P
A
D
-
I
F
A
-
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
----
V
GKPE
D
L
Y
D
N
P
V
S
I
Q
V
A
S
L
IGEINELEGKVTNEGVVIGSLRFPVSVSSDRAIIGIRPEDVKLSKDVIKDDSWILVGKGKVKVIGYQGGLFRITITPLDSEEEIFTYSDHPIHSGEEVLVYVRKDKIKVFEK
106
HHSearch
78.37
33%
-109
* C1 *
3TUI
1
METN_ECOLI
C:
[23-250]
--
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
---------
T
T
-
L
S
E
S
E
L
T
K
A
-
R
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
--
L
-----------
P
-----
L
E
L
-----
D
-----
N
TPKDE
V
K
R
R
V
T
E
---
L
-------
L
S
---
L
V
G
L
G
D
-
K
H
-
D
-
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
-
E
-
M
D
V
V
K
-
R
-
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
----
Q
----
D
T
V
S
E
V
F
S
H
P
K
T
P
L
----------------------------------------------------------------------------------------------------------------
130
Fugue
78.19
32%
-101
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
--
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
---------
T
T
-
L
S
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
--
L
-----------
P
-----
L
E
L
-----
D
NTPKD
E
-----
V
K
R
R
V
T
E
---
L
-------
L
S
---
L
V
G
L
G
D
-
K
H
-
D
-
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
-
E
M
D
V
V
-
K
-
R
-
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
QDTV
S
----
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
IQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV-------------
105
HHSearch
77.24
33%
-107
- C1 -
1Z47
1
?
A:
[15-233]
----
I
E
F
V
G
V
E
K
I
Y
P
G
G
---
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
---------
T
D
-
L
P
P
------
Q
K
R
N
V
G
L
V
F
Q
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
S
--
F
-----------
G
-----
L
R
E
-----
K
-----
R
VP
K
D
E
M
D
A
R
V
R
E
---
L
-------
L
R
---
F
M
R
L
E
S
-
Y
A
-
N
-
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
-
D
-
Q
E
E
A
L
-
E
-
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
----
F
----
G
T
P
E
E
V
Y
E
K
P
G
T
L
F
----------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
76.93
39%
-116
- C1 -
4YMW
-
?
J:
[8-216]
----------
Y
K
N
F
--
G
S
L
E
V
L
K
G
--
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
---------
N
N
-
G
K
V
N
--
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
--
L
-----------
A
-----
P
V
K
-----
V
-----------
K
K
M
N
K
K
E
---
A
EELAVDL
L
A
---
K
V
G
L
L
D
-
K
K
-
D
-
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
-
A
R
E
-
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
----
E
----
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
----------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
76.69
39%
-113
- C1 -
4YMT
-
?
J:
[8-216]
----------
Y
K
N
F
--
G
S
L
E
V
L
K
G
--
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
---------
N
N
-
G
K
V
N
--
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
--
L
-----------
A
-----
P
V
K
-----
V
-----------
K
K
M
N
K
K
E
---
A
EELAVDL
L
A
---
K
V
G
L
L
D
-
K
K
-
D
-
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
-
A
R
E
-
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
----
E
----
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
----------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
76.59
39%
-114
- C1 -
4YMS
-
?
J:
[8-216]
----------
Y
K
N
F
--
G
S
L
E
V
L
K
G
--
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
---------
N
N
-
G
K
V
N
--
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
--
L
-----------
A
-----
P
V
K
-----
V
-----------
K
K
M
N
K
K
E
---
A
EELAVDL
L
A
---
K
V
G
L
L
D
-
K
K
-
D
-
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
-
A
R
E
-
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
----
E
----
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
----------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
76.49
41%
-111
- C1 -
4U02
1
?
D:
[23-218]
--------------------------
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
---------
K
D
D
R
A
L
R
E
I
R
R
----
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
--
L
-----------
A
-----
P
M
R
-----
V
RRW--
P
-----
R
E
K
A
E
K
K
---
A
-------
L
E
LLE
R
V
G
I
L
D
-
Q
A
-
R
-
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G
G
-
M
T
M
V
V
V
T
H
-
E
-
M
G
F
-
A
R
E
-
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
----
E
----
G
R
P
E
E
I
F
T
R
P
K
E
E
R
----------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
76.35
39%
-113
- C1 -
4YMU
2
?
J:
[8-216]
----------
Y
K
N
F
--
G
S
L
E
V
L
K
G
--
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
---------
N
N
-
G
K
V
N
--
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
--
L
-----------
A
-----
P
V
K
-----
V
-----------
K
K
M
N
K
K
E
---
A
EELAVDL
L
A
---
K
V
G
L
L
D
-
K
K
-
D
-
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
-
E
-
M
G
F
-
A
R
E
-
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
----
E
----
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
----------------------------------------------------------------------------------------------------------------
95
PsiBlast_CBE
76.02
33%
-104
- C1 -
3FVQ
3
FBPC_NEIG1
B:
[5-217]
----
L
H
I
G
H
L
S
K
S
F
Q
N
--
T
P
V
L
--
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
---------
F
S
-
K
N
T
N
L
P
V
R
E
R
R
--
L
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
A
YG
L
-----------
G
-----
N
G
K
-----
G
-----
R
-----
T
A
Q
E
R
Q
R
IEA
M
-------
L
E
---
L
T
G
I
S
E
-
L
A
-
G
-
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
-
D
-
R
E
E
-
A
L
Q
-
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
----
T
----
A
S
P
H
E
L
Y
R
Q
P
A
D
L
D
----------------------------------------------------------------------------------------------------------------
62
PsiBlast_CBE
76.01
35%
-119
- C1 -
1B0U
4
HISP_SALTY
A:
[13-233]
----------
H
K
R
Y
--
G
G
H
E
V
L
K
G
--
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
Q
N
I
N
L
V
R
D
KDGQ
L
K
-
V
A
D
K
N
Q
L
R
L
L
R
T
R
L
T
M
V
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
V
---
M
-----------
E
-----
A
P
I
-----
Q
-----
V
-----
L
G
L
S
K
H
D
---
A
R
E
R
A
L
K
Y
L
A
---
K
V
G
I
D
E
-
R
A
-
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
E
E
G
K
T
M
V
-
V
V
T
H
-
E
-
M
G
F
-
A
-
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
----
E
----
G
D
P
E
Q
V
F
G
N
P
Q
S
P
R
----------------------------------------------------------------------------------------------------------------