@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs2022: (2015-12-12 )
MFDFFKKKVVKVCLVIFGIVLVSLLSLGFFYFSKGQVLSRFVAARSRTSGQAFDNIKEYMVWSDTGESITNDEANYANFEPLSKSEARKLGQEIKEGNKNDSMYLKRVGSRLGIFPDYRIANKPMSLTLKTNVPKLDVLLNQKKVATSNSDHFSVTVERLPRTHYTASLEGTSDGKEIKLKKDYDGKNQTIDLSVAFKSFTVTSNLMDGNLYFGDNRIAKLKDGSYSVENYPVTDGSKAYIKKVFNDGEITSHKQKLISIADNQTIKLDVDGLLNEKEAGQKLITAFNQLILYVSTGQDPQTLGTVFEKGAENDFYKGLKESIKAKFVTDNRKASHFTIPNIVLNKMTQVGKESYQVNFAADYDFNYDKSTDPDKKTYGHIIQNLTGNFIMKKSGNSYLISNDGKKDITVAKETNKVKADPVSIFPENLVGSWKGEVEDGTVTMTFDKDGKVTQKKVYKDSKSKESNHSAKVTKLEDKGNGLYLYQYESGTDTTTFVTGGIGGLKVKYAYGIKIEGNKIIPVIWQTSSDGEFDYHKPLLSKPLTKQ
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------.........10........20-----..-------.......30..-.-...---..40........50........60........70.....-...80........90....---....100.......110.......120-........130..---.....140..-.....150-......--..160.......170.......180.......190....----...--------200.......210-..-----.....220-.----...------------------...230....-...-240.-....--..250-.-...--..--------------...260.......270.....----..280..--...-------..290...-.-.--..300.----......-310....--..-.320.......330.......340.--......350.......-360.......370....---...380.......390...-------------....400.......410.....--..420.......430.......440....-....-450.......460..-....--.470.-.---.....480--------........490........500.--.--.....510.......520.......530.......540....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------M
F
D
F
F
K
K
K
V
V
K
V
C
L
V
I
F
G
I
V
------
L
V
-------
S
L
L
S
L
G
F
F
YFS-
K
-
G
Q
V
---
L
S
R
F
V
A
A
RSRTSG
Q
A
F
D
N
I
K
E
Y
M
V
WSDTGESITNDEANY-ANFEPL
S
K
S
E
A
R
K
L
G
Q
E
I
K
---EGNKN
D
S
M
Y
L
K
R
V
G
S
RLGIFPDYRIA--NK
P
M
S
L
T
L
KTNVP---
K
L
D
V
L
LNQKK-VATSNSD--
H
F
S
V
T
V
--
E
RLPRT
H
Y
T
A
SLEGTSDG
K
E
I
K
L
KKDYDGKN
Q
T
I
D
L
S
V
A
----
F
K
S
--------
F
T
V
T
SNLMDG
N
L
Y
-FG-----DN
R
I
A
KLK-D----GSY------------------SV
E
N
Y
PVTDG-
S
K
A
-
Y
I
K
K
-
V
FND--GEI---
T
-
S
H
K
--
Q
K
--------------
L
I
S
IADN
Q
T
I
K
L
DVDGLL
N
E
K
----
E
A
G
Q
K
L
I
--
T
A
F
-------
N
Q
L
I
L
Y
V
S-T-G--QD
P
Q
T
L
----
G
T
V
F
EK-GAE
N
D
F
Y
--
K
G
-
L
K
E
S
I
K
A
K
F
VTDNRKASHFT
I
P
N
I
V
--
L
N
K
M
T
Q
VGKE
S
Y
Q
V
N
F
-
A
A
D
Y
DFNYDKSTDPD
K
K
---
T
Y
G
H
I
I
Q
NLTG
N
F
I
M
KKSG-------------N
S
Y
L
ISNDGKK
D
I
T
V
AKETNKV--KADPVSI
F
P
E
N
L
V
GSWKGEVED
G
T
-
V
T
M
T
-FDKD-GK
V
T
Q
K
K
V
YKDSKSK-ESNH--SA
K
V
T
-
K
---
L
EDKGN
G
---------
L
Y
L
Y
Q
YESG-TD
T
T
T
F
V
TGGIG
G
--
L
--
K
V
K
Y
A
Y
G
I
K
I
EG
N
K
I
I
P
V
I
W
QTSSDGEFDYHK
P
L
LSKPLTKQ
28
Fugue
71.71
18%
-7
* C5 *
4D0L
2
PI4KB_HUMAN
A:
[10-566]
-------------------------------------------------------------------------------S
W
L
L
R
L
F
E
S
K
L
F
D
I
S
M
A
I
S
Y
L
Y
N
SKE
P
G
V
Q
-------
A
Y
I
G
N
R
L
F
C
F
R
-
N
-
E
D
V
D
F
Y
L
P
Q
L
L
N
M
Y
I
H
M
D
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D
A
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K
P
Y
I
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--
H
R
C
R
Q
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I
N
F
S
L
Q
C
-
A
L
L
L
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A
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S
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G
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K
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L
I
L
SRL
A
P
E
R
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F
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S
L
M
A
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K
R
L
A
T
L
P
T
------
K
E
Q
K
T
Q
R
L
I
S
E
L
S
---
L
L
N
H
K
L
P
A
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V
W
L
P
T
A
G
F
D
--
H
H
V
V
R
V
-----
P
H
T
Q
A
-------------
V
V
L
N
S
K
D
K
A
P
Y
L
I
Y
V
E
V
L
E
C
EN
F
D
T
--------
T
S
V
P
A
R
I
P
E
N
P
S
A
-
V
A
LKEP
W
Q
E
K
V
R
R
I
R
-
E
----
G
S
P
YG----------------
H
L
P
N
W
R
L
L
-----
S
-
V
I
V
K
-
C
G
D
D
L
R
Q
E
L
---
L
-
A
F
Q
V
L
K
Q
--------------
L
Q
S
I
W
E
Q
E
R
V
P
L
W
I
K
P
------------
Y
K
I
L
V
I
S
A
D
-------
S
G
M
I
E
P
V
V
-
N
-
A
--
V
S
I
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Q
V
----
K
K
Q
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Q
L
-
S
L
L
D
Y
F
L
--
Q
E
-
H
G
S
Y
T
T
E
A
F
L
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A
Q
R
N
F
V
Q
S
C
A
G
Y
C
L
--
V
C
Y
L
L
Q
V
-
K
D
R
H
N
G
N
I
-
L
L
D
A
E
-----------------
G
H
I
I
H
-
I
D
F
G
F
I
L
S
S
S
S
-------------
A
F
K
L
---------------
T
T
E
--
F
V
D
V
M
G
G
L
D
G
D
M
F
N
Y
Y
K
M
L
M
L
Q
G
L
-
I
A
A
R
--------------------
K
-
H
M
D
K
--
V
V
Q
I
V
-
E
---
I
M
Q
Q
G
S
Q
---------
L
P
C
F
H
G
S
S
-----------
T
I
R
N
--
L
--
K
E
R
F
H
M
S
M
T
---
E
E
Q
L
Q
L
L
V
E
Q
M
V
D
G
S
M
R
S
------------
32
Fugue
68.19
17%
20
- C1 -
4NL4
3
?
H:
[18-747]
SVAHVALPVPLPRTFDYLLPEGMAVKAGCRVRVPFGKQERIGIVAAVSERSELPLDELKPVAEALDDEPVFSTTVWRLLMW
A
A
E
Y
Y
H
H
P
I
G
D
V
L
F
H
A
L
P
V
M
------
L
R
QGKPA--
S
A
T
P
L
W
Y
W
F
A
T
-
E
Q
G
Q
V
---
V
D
L
N
G
L
K
R
S
R
K
Q
Q
Q
A
L
A
A
L
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I
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Q
V
G
E
L
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F
N
E
A
A
L
-
Q
A
L
R
G
K
G
L
A
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L
A
C
E
A
T
D
W
R
---
S
A
Y
S
V
A
G
E
R
L
R
L
N
T
E
Q
A
T
A
V
G
A
I
H
S
A
--
A
D
R
F
S
A
W
L
L
A
G
I
T
GSG
K
T
E
V
Y
L
S
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L
E
-
N
V
L
A
Q
G
R
--
Q
A
L
V
M
V
--
P
E
I
G
L
T
P
Q
T
I
A
R
F
R
Q
R
F
N
A
P
V
E
V
L
--
H
S
G
L
N
D
S
E
R
L
S
A
W
----
L
K
A
KNGEAAIV
I
G
T
R
S
S
L
F
T
P
F
K
D
-
L
G
-----
V
I
V
I
D
E
E
H
-
D
----
S
S
Y
KQQEGWRYHARDLAVWRA
H
S
E
Q
I
P
I
I
L
G
-
S
A
T
-
P
A
L
E
-
T
L
H
N
--
V
R
Q
---
G
-
K
Y
R
--
Q
L
--------------
T
L
S
K
P
A
Q
Q
H
V
-
L
D
L
K
G
Q
P
L
Q
A
----
G
L
S
P
A
L
I
--
S
R
M
RQHLQAD
N
Q
V
I
L
F
L
N
R
R
-
G
--
F
A
P
A
L
L
CHDC
G
W
I
A
E
C
-
P
R
C
D
S
Y
Y
TL
H
Q
-
A
Q
H
H
L
R
C
H
H
C
D
S
Q
R
P
I
P
R
-
Q
C
P
S
C
G
--
S
T
H
L
V
P
V
G
I
G
T
E
Q
L
E
Q
-
A
L
A
P
L
F
P
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V
P
I
S
R
I
D
R
H
LAA
V
H
R
G
G
A
R
I
L
I
G
T
Q
M
L
A
K
G
H
HFPDVTLVSLLDV
D
G
A
L
F
S
A
D
F
R
S
A
E
R
F
A
Q
L
Y
T
Q
V
SG
R
A
G
R
A
G
K
Q
G
E
V
I
L
Q
T
H
H
P
E
-
H
P
L
L
-
Q
T
L
L
-
Y
K
G
Y
-
D
A
F
A
E
Q
A
L
A
E
R
Q
T
M
Q
-
L
P
P
W
--
T
S
H
V
L
I
R
---
A
E
D
H
N
N
Q
QAPLFLQQL
R
N
L
L
Q
A
S
P
L
-
A
D
E
K
L
W
V
L
G
P
V
P
A
--
L
RW
Q
I
L
L
Q
H
P
S
R
V
R
L
Q
H
I
V
S
G
T
L
A
L
I
N
T
L
P
E
A
W
V
L
D
V
--
D
P
I
E
G
-
23
Fugue
61.36
22%
20
- C2 -
4R7F
7
?
A:
[2-398]
---------------------------------------------------------------------------------
Q
V
K
F
F
T
D
V
N
S
K
Q
I
K
T
L
Q
V
K
V
------
A
G
-------
E
L
I
S
E
P
Y
I
A
L
G
G
E
-
E
Q
I
---
E
I
N
F
D
G
L
G
S
G
Y
T
R
Y
A
Y
N
V
V
H
C
N
A
D
W
T
Q
S
Q
L
S
----
P
I
E
Y
M
N
G
F
Q
----------
G
T
T
I
D
---
D
-------
F
A
N
S
I
G
T
T
T
Q
-
Y
S
N
Y
R
L
L
L
P
N
D
D
V
Q
F
K
V
S
G
N
Y
A
----
I
Q
V
Y
N
E
D
T
P
-
D
Q
I
I
F
T
A
--
C
F
S
V
V
E
-----
P
V
V
N
I
S
A
S
V
S
G
N
T
D
-------
I
D
T
N
Q
S
H
Q
Q
V
S
F
N
I
N
----
N
K
N
--------
F
P
I
T
Y
P
Q
T
D
L
K
I
F
V
Y
Q
-----
D
N
R
---------------------------------------
R
D
N
-
A
V
T
-
D
L
Q
P
M
S
I
L
E
--
N
Q
I
---
S
Y
T
Y
N
--
R
N
--------------
L
I
F
P
A
G
N
E
---------------------------------------------------------------
Y
R
R
M
E
F
L
S
N
K
Y
--
N
G
M
H
V
E
N
I
S
F
H
---------------------------
N
P
Y
Y
N
V
E
L
M
T
---
D
Y
R
R
D
K
G
T
Y
Q
Y
D
----------
Q
D
Q
D
G
R
F
F
I
R
C
S
D
-------------
C
-----
N
D
P
D
T
E
A
D
Y
Y
I
V
H
F
T
L
--
A
C
D
P
L
P
---------------
D
G
S
-
V
Y
L
N
-
G
E
L
F
-
N
N
V
L
------
D
E
K
S
K
M
G
Y
N
F
E-
T
K
Q
Y
E
-
K
---
A
V
L
L
K
Q
G
---------
S
Y
N
Y
Q
Y
L
F
V
P
T
G
S
S
V
G
Q
T
G
P
I
E
G
NY
Y
--
Q
T
Q
N
E
Y
S
I
Y
V
Y
Y
R
P
M
---------
G
A
R
Y
D
---
R
L
I
G
V
T
T
V
R
N
30
Fugue
43.12
18%
-88
- C5 -
3T7Z
3
Y694_METJA
A:
[1-119]
-----------------------------------------------------------------------------------------
M
I
Y
V
T
F
T
P
Y
G
A
F
------
G
V
K
DNKEVS
G
L
E
D
I
E
Y
K
K
L
F
-
N
-
E
E
E
---
I
P
D
I
M
F
K
L
K
T
Q
P
N
K
I
A
D
E
L
K
E
E
W
-----
G
D
E
I
K
L
E
T
L
S
----------
T
E
P
F
N
I
G
E
F
L
R
---
N
-------
N
L
F
K
V
G
K
E
L
G
Y
F
N
N
Y
D
E
F
--
R
K
K
M
H
Y
W
S
T
E
L
T
K
---
K
V
I
K
S
Y
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
41.74
14%
18
- C3 -
3CMG
-
?
A:
[591-653]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
T
--------
F
M
A
F
T
T
A
P
E
A
E
L
F
-
V
N
-----
G
V
S
C
G
K
Q
K
A
D
TY--
S
T
V
------------------
V
W
K
N
V
K
L
T
S
G
E
N
I
I
-
R
V
T
T
-
P
--
G
--
K
K
P
---
L
-
T
D
E
--
V
T
--------------
V
E
Y
K
E
D
R
H
H
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
40.47
15%
31
- C3 -
3FN9
-
?
A:
[599-664]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
A
V
T
V
Y
S
N
I
G
---
T
P
K
V
Y
L
N
G
Q
E
-
L
S
G
I
R
N
G
YT
D
V
H
Y
V
F
D
N
V
S
L
A
D
G
K
N
I
L
K
A
V
V
S
T
K
G
K
E
Y
T
D
E
I
E
W
N
Y
S
G
E
K
N
R
E
I
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
38.78
30%
-3
- C4 -
4O4F
3
?
A:
[143-216]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
E
Y
I
K
L
-
F
F
N
D
G
K
K
Y
R
K
E
L
V
P
Y
F
I
S
Q
L
D
K
M
I
E
V
M
K
K
R
E
Y
K
M
F
-
S
S
S
V
L
F
V
Y
D
S
T
T
T
L
E
D
K
---
K
Y
N
C
K
M
I
D
F
A
H
N
W
I
L
S
E
E
E
-------------
C
T
V
E
D
G
F
L
F
G
L
N
N
L
K
S
I
L
E
D
I
E
--
N
E
F
K
S
L
---------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
38.28
26%
35
- C3 -
4NN5
-
IL7RA_MOUSE
B:
[20-130]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-
D
----
H
S
F
------------------
W
C
H
S
Q
L
E
V
D
G
-
S
Q
H
-
L
L
T
C
-
A
F
N
D
--
S
D
I
---
N
-
T
A
N
--
L
E
F
Q
I
C
G
ALLRVK
C
L
T
L
N
K
L
Q
D
I
Y
F
I
K
T
S
E
F
L
L
I
G
S
S
N
I
C
V
K
L
G
Q
K
N
L
--
T
C
K
-------
N
M
A
I
N
T
I
V
-
K
-
A
--
E
A
P
S
D
L
----
K
V
V
Y
R
K
-
E
A
-
N
D
F
L
--
V
T
-
F
N
A
P
H
L
K
K
K
Y
L
K
K
V
K
H
D
V
A
Y
R
P
A
R
G
--
E
S
N
W
T
H
V
S
L
F
H
T
R
T
T
I
-
P
Q
R
K
L
R
P
K
A
M
Y
E
I
K
V
R
S
---
I
P
H
N
D
Y
F
K
G
F
W
S
E
W
S
P
S
S
T
-------------
F
E
T
P
E
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
37.69
30%
-1
- C4 -
4O4B
-
?
B:
[145-218]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
E
Y
I
K
L
-
F
F
N
D
G
K
K
Y
R
K
E
L
V
P
Y
F
I
S
Q
L
D
K
M
I
E
V
M
K
K
R
E
Y
K
M
F
-
S
S
S
V
L
F
V
Y
D
S
T
T
T
L
E
D
K
---
K
Y
N
C
K
M
I
D
F
A
H
N
W
I
L
S
E
E
E
-------------
C
T
V
E
D
G
F
L
F
G
L
N
N
L
K
S
I
L
E
D
I
E
--
N
E
F
K
S
L
---------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
37.53
16%
42
* C6 *
3J7W
-
CAPSA_BPT7
A:
[2-344]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
M
T
G
G
Q
Q
M
G
T
N
Q
G
K
G
V
V
A
A
G
D
K
L
A
L
F
----
L
K
V
--------
F
G
G
E
V
L
T
A
F
A
R
T
S
-
V
T
-----
T
S
R
H
M
V
R
S
-
I
----
S
S
G
------------------
K
S
A
Q
F
P
V
L
G
R
-
T
Q
A
A
Y
L
A
P
-
G
E
N
L
--
D
D
K
R
K
D
I
-
K
H
T
--
E
K
--------------
V
I
T
I
D
G
L
L
T
A
D
V
L
I
Y
D
I
E
D
A
M
----
N
H
Y
D
V
R
S
--
E
Y
T
-------
S
Q
L
G
E
S
L
A
-
M
-
A
--
A
D
G
A
V
L
----
A
E
I
A
G
L
-
C
N
V
E
S
K
Y
--
N
E
-
N
I
E
G
L
G
T
A
T
V
I
E
T
T
Q
N
K
A
A
L
T
D
Q
V
A
--
L
G
K
E
I
I
A
A
L
T
K
A
R
A
A
L
-
T
K
N
Y
V
P
A
A
D
R
V
F
Y
C
D
P
D
---
S
Y
S
A
I
L
A
A
L
-----
M
P
N
A
A
-------------
N
Y
A
A
L
I
D
P
E
K
G
S
I
R
N
V
M
G
F
E
V
V
--
E
V
------
P
H
L
T
A
G
G
A
G
T
A
R
E
G
T
T
G
Q
K
H
V
-
F
P
A
N
-
K
G
E
G
N
V
K
V
A
K
D
N
V
I
G
-
L
F
M
H
RS
A
V
G
T
V
-
K
---
L
R
D
L
A
L
E
---------
R
A
R
R
A
N
F
Q
A
-
D
Q
I
I
A
K
Y
A
M
G
H
G
G
--
L
--
R
P
E
A
A
G
A
V
V
F
K
V
------------------------------
3
PsiBlast_PDB
37.29
30%
-0
- C4 -
4O4E
2
?
A:
[143-216]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
E
Y
I
K
L
-
F
F
N
D
G
K
K
Y
R
K
E
L
V
P
Y
F
I
S
Q
L
D
K
M
I
E
V
M
K
K
R
E
Y
K
M
F
-
S
S
S
V
L
F
V
Y
D
S
T
T
T
L
E
D
K
---
K
Y
N
C
K
M
I
D
F
A
H
N
W
I
L
S
E
E
E
-------------
C
T
V
E
D
G
F
L
F
G
L
N
N
L
K
S
I
L
E
D
I
E
--
N
E
F
K
S
L
---------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
37.10
30%
0
- C4 -
4O4D
5
?
A:
[143-216]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
E
Y
I
K
L
-
F
F
N
D
G
K
K
Y
R
K
E
L
V
P
Y
F
I
S
Q
L
D
K
M
I
E
V
M
K
K
R
E
Y
K
M
F
-
S
S
S
V
L
F
V
Y
D
S
T
T
T
L
E
D
K
---
K
Y
N
C
K
M
I
D
F
A
H
N
W
I
L
S
E
E
E
-------------
C
T
V
E
D
G
F
L
F
G
L
N
N
L
K
S
I
L
E
D
I
E
--
N
E
F
K
S
L
---------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
36.89
30%
3
- C4 -
4O4C
-
?
A:
[150-223]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
E
Y
I
K
L
-
F
F
N
D
G
K
K
Y
R
K
E
L
V
P
Y
F
I
S
Q
L
D
K
M
I
E
V
M
K
K
R
E
Y
K
M
F
-
S
S
S
V
L
F
V
Y
D
S
T
T
T
L
E
D
K
---
K
Y
N
C
K
M
I
D
F
A
H
N
W
I
L
S
E
E
E
-------------
C
T
V
E
D
G
F
L
F
G
L
N
N
L
K
S
I
L
E
D
I
E
--
N
E
F
K
S
L
---------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
36.51
26%
18
- C3 -
4NN7
-
IL7RA_MOUSE
B:
[22-130]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
S
F
------------------
W
C
H
S
Q
L
E
V
D
G
-
S
Q
H
-
L
L
T
C
-
A
F
N
D
--
S
D
I
---
N
-
T
A
N
--
L
E
F
Q
I
C
G
ALLRVK
C
L
T
L
N
K
L
Q
D
I
Y
F
I
K
T
S
E
F
L
L
I
G
S
S
N
I
C
V
K
L
G
Q
K
N
L
--
T
C
K
-------
N
M
A
I
N
T
I
V
-
K
-
A
--
E
A
P
S
D
L
----
K
V
V
Y
R
K
-
E
A
-
N
D
F
L
--
V
T
-
F
N
A
P
H
L
K
K
K
Y
L
K
K
V
K
H
D
V
A
Y
R
P
A
R
G
--
E
S
N
W
T
H
V
S
L
F
H
T
R
T
T
I
-
P
Q
R
K
L
R
P
K
A
M
Y
E
I
K
V
R
S
---
I
P
H
N
D
Y
F
K
G
F
W
S
E
W
S
P
S
S
T
-------------
F
E
T
P
E
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
35.42
26%
34
- C3 -
4NN6
-
IL7RA_MOUSE
B:
[21-130]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
----
H
S
F
------------------
W
C
H
S
Q
L
E
V
D
G
-
S
Q
H
-
L
L
T
C
-
A
F
N
-----
I
---
N
-
T
A
N
--
L
E
F
Q
I
C
G
ALLRVK
C
L
T
L
N
K
L
Q
D
I
Y
F
I
K
T
S
E
F
L
L
I
G
S
S
N
I
C
V
K
L
G
Q
K
N
L
--
T
C
K
-------
N
M
A
I
N
T
I
V
-
K
-
A
--
E
A
P
S
D
L
----
K
V
V
Y
R
K
-
E
A
-
N
D
F
L
--
V
T
-
F
N
A
P
H
L
K
K
K
Y
L
K
K
V
K
H
D
V
A
Y
R
P
A
R
G
--
E
S
N
W
T
H
V
S
L
F
H
T
R
T
T
I
-
P
Q
R
K
L
R
P
K
A
M
Y
E
I
K
V
R
S
---
I
P
H
N
D
Y
F
K
G
F
W
S
E
W
S
P
S
S
T
-------------
F
E
T
P
E
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
33.41
21%
16
- C3 -
3FN9
-
?
A:
[599-641]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
A
--------
V
T
V
Y
S
N
I
G
T
P
K
V
Y
-
L
N
-----
G
Q
E
L
S
G
I
R
-
N
G
YTD
V
H
Y
------------------
V
F
D
N
V
S
L
A
D
G
-
K
N
I
-
L
K
A
V
-
V
S
T
K
--
G
K
E
---
Y
-
T
D
E
--
I
E
--------------
W
N
Y
S
G
E
K
N
R
E
I
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
29.30
25%
32
- C3 -
4AYJ
2
?
A:
[29-146]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
-
D
----
Q
S
F
------------------
I
I
E
Y
Y
V
F
T
D
S
-
P
K
L
-
Y
D
E
E
---
N
N
--
K
H
I
---
H
-
R
I
K
--
Q
K
--------------
N
L
G
W
P
D
N
T
L
K
R
F
H
I
F
L
R
I
K
E
Q
L
---
E
R
E
T
D
Y
L
--
F
F
F
-------
N
A
N
L
L
F
T
S
-
P
I
G
--
K
--
E
I
L
----
P
P
S
D
S
N
-
G
L
L
G
T
M
H
--
P
G
-
F
Y
N
K
P
N
S
E
F
T
Y
E
R
R
D
A
S
T
A
Y
I
P
E
G
E
--
G
R
Y
Y
Y
A
G
G
L
S
G
G
C
T
K
A
-
Y
L
K
L
C
T
T
I
C
S
W
V
D
R
D
A
T
---
N
H
I
I
P
I
W
H
D
E
S
L
I
N
K
Y
F
L
D
-------------
N
P
P
A
I
T
L
S
P
A
Y
L
Y
P
E
G
W
L
L
P
F
E
--
P
I
I
L
I
R
D
K
-------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
27.33
17%
56
- C6 -
2LZ0
-
?
A:
[1-100]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-
S
H
E
-
G
E
P
V
-
V
G
M
D
--
K
S
L
---
F
-
A
G
N
--
T
V
--------------
I
R
E
I
T
V
Q
P
N
I
G
L
L
Y
D
G
M
F
S
G
C
----
T
A
L
E
K
L
I
--
L
T
G
-------
E
D
P
S
A
Y
S
A
-
G
-
D
GL
R
D
G
A
D
F
----
L
I
C
V
P
E
-
E
A
L
D
R
Y
R
--
R
D
-
Y
F
W
Q
T
Y
A
A
W
I
Q
P
M
E
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
27.11
18%
109
- C3 -
2UYW
2
?
A:
[4-37]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
C
N
L
Q
G
Q
W
R
N
K
L
-
G
S
N
-
L
I
I
E
S
V
S
Q
N
-
G
E
F
T
G
T
Y
F
T
S
V
S
L
T
N
-
S
T
I
R
--
I
S
P
L
T
-
G
---
Y
Q
K
L
T
E
K
---------
P
T
F
G
F
T
V
H
W
-
A
F
S
D
S
I
T
V
W
T
G
Q
C
--
F
--
L
N
E
K
G
E
E
I
L
H
T
M
W
L
L
R
S
S
Q
E
K
E
Q
D
N
W
T
G
T
R
V
G
A
N
T
F
T
R
L
---
12
HHSearch
26.88
14%
75
- C3 -
3GE2
4
?
A:
[43-109]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
A
Q
P
T
D
I
D
G
T
Y
T
G
Q
D
D
G
D
R
-
I
T
L
V
-
V
T
G
T
T
G
T
W
T
E
L
E
S
D
--
G
D
Q
K
---
V
K
--
Q
V
T
F
D
-
S
ANQ
R
M
I
I
G
D
D
---------
V
K
I
Y
T
V
N
G
N
-
Q
I
V
V
D
D
M
D
R
D
P
S
D
--
Q
--
I
V
L
T
K
-------------------------------------