@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu09670: (2016-06-15 )
MKVLVNGRLIGRSEASIDLEDRGYQFGDGIYEVIRVYKGVLFGLREHAERFFRSAAEIGISLPFSIEDLEWDLQKLVQENAVSEGAVYIQTTRGVAPRKHQYEAGLEPQTTAYTFTVKKPEQEQAYGVAAITDEDLRWLRCDIKSLNLLYNVMTKQRAYEAGAFEAILLRDGVVTEGTSSNVYAVINGTVRTHPANRLILNGITRMNILGLIEKNGIKLDETPVSEEELKQAEEIFISSTTAEIIPVVTLDGQSIGSGKPGPVTKQLQAAFQESIQQAASIS
Atome Classification :
(24 SA)
.........10........20........30......----..----40........50........60........70........80-----....-----....90........100-..-.-....110.......120........130.......140....-...150.......160.......-170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
V
L
VN
G
R
L
IGRSE
A
S
I
DLEDRGYQF
G
D
G
I
Y
E
V
I
R
V
Y
----
K
G
----
V
L
F
G
L
R
E
H
A
E
R
F
F
R
S
A
A
EIGISLPF
S
I
E
D
L
E
W
D
L
Q
K
L
V
Q
ENA-----VSEG-----
A
V
Y
I
Q
TTRGVAPR
K
H
Q
Y
-EA-G-LEPQT
T
A
Y
T
F
TVKKP-EQEQAY
G
V
A
A
ITDED
L
R
W
L
R
C
D
I
K
S
L
-
N
L
L
Y
N
V
M
T
K
Q
R
AYEAGA
F
E
A
I
L
L-RD
G
V
VTEGTSS
N
V
Y
A
V
I
NG
T
V
RTHPA
N
R
L
I
L
NGIT
R
M
N
I
L
G
L
I
EKNGIKLDETPV
S
E
E
E
L
K
Q
A
E
E
I
FISSTT
A
E
I
I
P
V
V
T
LDGQSIGSGKPG
P
V
T
K
Q
L
Q
A
A
F
Q
E
S
I
Q
Q
A
ASIS
12
PsiBlast_PDB
89.25
41%
-87
- C- -
4TM5
-
?
A:
[20-295]
--------
L
V
P
L
S
E
A
R
V
P
V
L
D
R
G
F
I
F
G
D
G
V
Y
E
V
V
P
I
Y
A
EGA
R
R
----
A
P
F
R
I
A
Q
H
L
A
R
L
A
R
S
L
K
K
I
G
I
A
D
P
H
D
E
A
G
W
R
A
L
V
A
R
L
V
D
A
N
A
-----
A
A
L
G
DG
Q
H
A
I
V
Y
I
Q
V
T
R
G
V
A
K
R
G
H
A
F
-
P
A
-
N
-
A
V
P
T
V
F
A
M
A
S
P
L
A
L
P
T
D
A
Q
R
A
Q
G
V
H
C
V
T
A
E
D
R
R
W
L
H
C
D
I
K
S
V
-
S
L
L
G
N
V
L
M
A
Q
H
A
A
E
H
D
A
A
E
T
I
Q
L
-
R
D
G
N
V
T
E
G
S
S
S
N
V
W
I
V
K
N
G
E
L
I
A
P
P
R
S
N
R
I
L
E
G
I
R
Y
A
L
V
E
E
L
A
E
E
C
G
I
R
F
V
A
R
E
I
N
E
A
E
L
R
A
A
D
E
I
L
L
T
S
A
T
K
E
I
L
P
V
T
R
L
D
D
L
P
V
Q
G
G
R
P
G
P
V
F
D
A
L
Y
A
A
Y
Q
R
A
--------
31
PsiBlast_CBE
88.83
41%
-93
- C8 -
4M0J
1
?
B:
[28-303]
--------
L
V
P
L
S
E
A
R
V
P
V
L
D
R
G
F
I
F
G
D
G
V
Y
E
V
V
P
I
Y
A
EGA
R
R
----
A
P
F
R
I
A
Q
H
L
A
R
L
A
R
S
L
K
K
I
G
I
A
D
P
H
D
E
A
G
W
R
A
L
V
A
R
L
V
D
A
N
A
-----
A
A
L
G
DG
Q
H
A
I
V
Y
I
Q
V
T
R
G
V
A
K
R
G
H
A
F
-
P
A
-
N
-
A
V
P
T
V
F
A
M
A
S
P
L
A
L
P
T
D
A
Q
R
A
Q
G
V
H
C
V
T
A
E
D
------
D
I
K
S
V
-
S
L
L
G
N
V
L
M
A
Q
H
A
A
E
H
D
A
A
E
T
I
Q
L
-
R
D
G
N
V
T
E
G
S
S
S
N
V
W
I
V
K
N
G
E
L
I
A
P
P
R
--------
R
Y
A
L
V
E
E
L
A
E
E
C
G
I
R
F
V
A
R
E
I
N
E
A
E
L
R
A
A
D
E
I
L
L
T
S
A
T
K
E
I
L
P
V
T
R
L
D
D
L
P
V
Q
G
G
R
P
G
P
V
F
D
A
L
Y
A
A
Y
Q
R
A
--------
11
PsiBlast_PDB
88.48
41%
-90
- C8 -
4M0J
-
?
A:
[28-303]
--------
L
V
P
L
S
E
A
R
V
P
V
L
D
R
G
F
I
F
G
D
G
V
Y
E
V
V
P
I
Y
A
EGA
R
R
----
A
P
F
R
I
A
Q
H
L
A
R
L
A
R
S
L
K
K
I
G
I
A
D
P
H
D
E
A
G
W
R
A
L
V
A
R
L
V
D
A
N
A
-----
A
A
L
G
DG
Q
H
A
I
V
Y
I
Q
V
T
R
G
V
A
K
R
G
H
A
F
-
P
A
-
N
-
A
V
P
T
V
F
A
M
A
S
P
L
A
L
P
T
D
A
Q
R
A
Q
G
V
H
C
V
T
A
E
D
-----
C
D
I
K
S
V
-
S
L
L
G
N
V
L
M
A
Q
H
A
A
E
H
D
A
A
E
T
I
Q
L
-
R
D
G
N
V
T
E
G
S
S
S
N
V
W
I
V
K
N
G
E
L
I
A
P
P
R
S
N
R
I
L
E
G
I
R
Y
A
L
V
E
E
L
A
E
E
C
G
I
R
F
V
A
R
E
I
N
E
A
E
L
R
A
A
D
E
I
L
L
T
S
A
T
K
E
I
L
P
V
T
R
L
D
D
L
P
V
Q
G
G
R
P
G
P
V
F
D
A
L
Y
A
A
Y
Q
R
A
--------
8
PsiBlast_PDB
88.44
43%
-67
- C8 -
2DAB
1
DAAA_BACYM
A:
[4-280]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
A
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
P
K
P
L
---
4
PsiBlast_PDB
88.40
44%
-76
- C8 -
4DAA
3
DAAA_BACYM
A:
[4-276]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
-------
28
PsiBlast_CBE
88.10
43%
-72
- C8 -
1A0G
1
DAAA_BACYM
B:
[4-282]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
A
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
P
K
P
L
H
I
-
7
PsiBlast_PDB
87.91
43%
-68
- C8 -
1A0G
1
DAAA_BACYM
A:
[4-280]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
A
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
P
K
P
L
---
29
PsiBlast_CBE
87.65
43%
-76
- C8 -
5DAA
1
DAAA_BACYM
B:
[4-276]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
K
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
-------
27
PsiBlast_CBE
87.55
43%
-69
- C8 -
2DAB
1
DAAA_BACYM
B:
[4-282]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
A
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
P
K
P
L
H
I
-
25
PsiBlast_CBE
87.45
44%
-72
- C8 -
3LQS
2
DAAA_BACYM
B:
[4-278]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
P
K
-----
21
PsiBlast_CBE
87.44
43%
-75
- C8 -
2DAA
2
DAAA_BACYM
B:
[4-277]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
P
------
48
HHSearch
87.32
40%
-81
- C- -
4TM5
-
?
A:
[15-300]
---
A
S
R
E
E
L
V
P
L
S
E
A
R
V
P
V
L
D
R
G
F
I
F
G
D
G
V
Y
E
V
V
P
I
Y
----
A
E
GA
R
R
A
P
F
R
I
A
Q
H
L
A
R
L
A
R
S
L
K
K
I
G
I
A
D
P
H
D
E
A
G
W
R
A
L
V
A
R
L
V
D
A
N
A
AALGD
G
Q
H
A
-----
I
V
Y
I
Q
V
T
R
G
V
A
K
-
R
G
H
A
-
F
P
A
N
-
A
V
P
T
V
F
A
M
A
S
P
L
A
L
P
T
D
A
Q
R
A
Q
G
V
H
C
V
T
A
E
D
R
R
W
L
H
C
D
I
K
S
V
-
S
L
L
G
N
V
L
M
A
Q
H
A
A
E
H
D
A
A
E
T
I
Q
L
-
R
D
G
N
V
T
E
G
S
S
S
N
V
W
I
V
K
N
G
E
L
I
A
P
P
R
S
N
R
I
L
E
G
I
R
Y
A
L
V
E
E
L
A
E
E
C
G
I
R
F
V
A
R
E
I
N
E
A
E
L
R
A
A
D
E
I
L
L
T
S
A
T
K
E
I
L
P
V
T
R
L
D
D
L
P
V
Q
G
G
R
P
G
P
V
F
D
A
L
Y
A
A
Y
Q
R
A
K
A
H
E
M
---
26
PsiBlast_CBE
87.13
43%
-75
- C8 -
1G2W
3
DAAA_BACYM
B:
[4-277]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
S
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
P
------
6
PsiBlast_PDB
86.80
43%
-75
- C8 -
1G2W
3
DAAA_BACYM
A:
[4-277]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
S
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
P
------
1
PsiBlast_PDB
86.75
43%
-74
- C8 -
1DAA
1
DAAA_BACYM
A:
[4-277]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
P
------
23
PsiBlast_CBE
86.70
44%
-73
- C8 -
4DAA
3
DAAA_BACYM
B:
[4-276]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
-------
24
PsiBlast_CBE
86.65
44%
-75
- C8 -
3DAA
2
DAAA_BACYM
B:
[4-276]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
-------
5
PsiBlast_PDB
86.53
44%
-72
- C8 -
3LQS
2
DAAA_BACYM
A:
[4-278]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
P
K
-----
22
PsiBlast_CBE
86.52
43%
-74
- C8 -
1DAA
1
DAAA_BACYM
B:
[4-277]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
P
------
2
PsiBlast_PDB
86.47
43%
-73
- C8 -
2DAA
2
DAAA_BACYM
A:
[4-277]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
P
------
9
PsiBlast_PDB
86.07
43%
-76
- C8 -
5DAA
1
DAAA_BACYM
A:
[4-276]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
K
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
-------
3
PsiBlast_PDB
86.06
44%
-72
- C8 -
3DAA
2
DAAA_BACYM
A:
[4-276]
---
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
P
E
N
-
T
-
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
-------
32
Fugue
85.49
42%
-74
- C8 -
5DAA
1
DAAA_BACYM
A:
[1-277]
G
Y
T
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
-
P
E
-
N
T
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
N-
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
R
-
N
N
T
V
T
K
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
K
I
P
------
43
HHSearch
84.42
44%
-68
* C8 *
3DAA
2
DAAA_BACYM
A:
[2-274]
-
Y
T
L
W
N
D
Q
I
V
K
D
E
E
V
K
I
D
K
E
D
R
G
Y
Q
F
G
D
G
V
Y
E
V
V
K
V
Y
----
N
G
----
E
M
F
T
V
N
E
H
I
D
R
L
Y
A
S
A
E
K
I
R
I
T
I
P
Y
T
K
D
K
F
H
Q
L
L
H
E
L
V
E
K
N
E
-----
L
N
T
G
-----
H
I
Y
F
Q
V
T
R
G
T
S
P
R
A
H
Q
F
-
P
E
-
N
T
V
K
P
V
I
I
G
Y
T
K
E
N
P
R
P
-
L
E
N
L
E
K
G
V
K
A
T
F
V
E
D
I
R
W
L
R
C
D
I
K
S
L
-
N
L
L
G
A
V
L
A
K
Q
E
A
H
E
K
G
C
Y
E
A
I
L
H
-
R
N
N
T
V
T
E
G
S
S
S
N
V
F
G
I
K
D
G
I
L
Y
T
H
P
A
N
N
M
I
L
K
G
I
T
R
D
V
V
I
A
C
A
N
E
I
N
M
P
V
K
E
I
P
F
T
T
H
E
A
L
K
M
D
E
L
F
V
T
S
T
T
S
E
I
T
P
V
I
E
I
D
G
K
L
I
R
D
G
K
V
G
E
W
T
R
K
L
Q
K
Q
F
E
T
---------