@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu23780: (2016-07-07 )
MKHIAGKRIWITGASGGLGERIAYLCAAEGAHVLLSARREDRLIEIKRKITEEWSGQCEIFPLDVGRLEDIARVRDQIGSIDVLINNAGFGIFETVLDSTLDDMKAMFDVNVFGLIACTKAVLPQMLEQKKGHIINIASQAGKIATPKSSLYSATKHAVLGYSNALRMELSGTGIYVTTVNPGPIQTDFFSIADKGGDYAKNVGRWMLDPDDVAAQITAAIFTKKREINLPRLMNAGTKLYQLFPALVEKLAGRALMKK
Atome Classification :
(31 SA)
.........10........20..--......30.........40........50..---..-...-..60--.........70---.----....----....80........90--..-.......100.......110.......120...--....-130.........140.......--150.......160.......170.........180.....-..-190.-----...----.----.---------.200...--..--..210.......220.......230.......240.......250.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKHIAG
K
R
I
W
I
TGASGG
L
G
E
R
I
A
--
Y
LCAAEG-
A
H
V
L
LSARRE
D
R
L
I
E
I
K
R
K
I
-
T
E
---
E
W-SGQ-
C
E
I
---
F
PL
D
V
G
R
L
E
D
----
I
----
A
R
V
R
----
D
QIG
S
I
D
V
L
I
NNA
G
F
---
G
I
-
F
E
T
V
L
D
S
T
L
D
D
M
K
A
M
F
DV
N
V
F
G
L
I
A
C
T
K
A
V
L
P
Q
--
M
L
E
Q-K--KG
H
I
I
N
IASQAGKIATP
K
S
--
S
L
Y
S
A
T
K
H
A
V
LGYS
N
A
L
R
M
E
L--SG
T
G
I
Y
V
T
TVNPGPIQ
T
-
D
F
-
F
S
I
A-----DKG----G----
D
---------
Y
A
K
N
VGR--WM--L
D
P
D
D
V
A
A
Q
I
T
A
A
I
F
TKKREIN
L
P
R
L
M
N
A
G
T
K
L
Y
Q
L
F
P
A
L
V
E
K
LA
G
R
A
LMKK
1
PsiBlast_PDB
76.06
35%
14
- C1 -
3RKU
1
YM71_YEAST
A:
[29-267]
-
E
R
L
A
K
K
T
V
L
I
T
G
A
S
A
G
I
G
K
A
T
A
L
E
Y
L
E
A
S
N
G
D
M
K
L
I
L
A
A
R
R
L
E
K
L
E
E
L
K
K
T
I
-
D
Q
---
E
F
P
N
A
K
-
V
H
V
---
A
Q
L
D
I
T
Q
A
E
K
----
I
K
P
F
I
E
N
L
P
----
Q
E
F
K
D
I
D
I
L
V
N
N
A
G
K
---
A
L
G
S
D
R
V
G
Q
I
A
T
E
D
I
Q
D
V
F
D
T
N
V
T
A
L
I
N
I
T
Q
A
V
L
P
I
--
F
Q
A
K
-
N
--
S
G
D
I
V
N
L
G
S
I
A
G
R
D
A
Y
P
T
G
--
S
I
Y
C
A
S
K
F
A
V
G
A
F
T
D
S
L
R
K
E
L
--
I
N
T
K
I
R
V
I
L
I
A
P
G
L
V
E
T
-
E
F
-
S
L
V
R
-----
Y
R
G
----
N
E
---
E
---------
Q
A
K
N
V
Y
K
DT
T
P
--
L
M
A
D
D
V
A
D
L
I
V
Y
A
T
S
R
K
Q
N
T
V
-------------------------------
124
HHSearch
75.40
29%
-84
- C1 -
3AI3
3
?
A:
[3-244]
-
M
G
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
--
E
G
F
A
K
E
G
-
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
---
K
F
-
G
V
R
-
V
L
E
---
V
A
V
D
V
A
T
P
E
G
----
V
----
D
A
V
V
E
S
V
R
S
S
F
G
G
A
D
I
L
V
N
N
A
G
T
---
G
S
-
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
L
V
M
A
A
V
R
L
A
R
G
L
V
P
G
--
M
R
A
R
-
G
--
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
--
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
-
P
D
-
W
I
K
T
-----
A
K
E
L
T
K
D
N
GG--
D
W
K
G
Y
L
Q
S
V
A
D
E
H
A
P
I
K
--
R
F
--
A
S
P
E
E
L
A
N
F
F
V
F
L
C
S
E
R
-----------------------------------
36
PsiBlast_CBE
74.77
33%
-96
- C1 -
3AI2
1
?
H:
[5-210]
---
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
--
E
G
F
A
K
E
G
-
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
---
K
F
-
G
V
R
-
V
L
E
---
V
A
V
D
V
A
T
P
E
G
VDAV
V
----
E
S
V
R
----
S
S
F
G
G
A
D
I
L
V
N
N
A
G
T
---
G
S
-
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
--
M
R
A
R
-
G
--
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
--
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
-
I
K
T
A
KELTK
D
N
G
----
G
----
D
---------
W
----------------------------------------------------------------
23
PsiBlast_CBE
74.72
35%
14
- C1 -
3RKU
1
YM71_YEAST
B:
[29-267]
-
E
R
L
A
K
K
T
V
L
I
T
G
A
S
A
G
I
G
K
A
T
A
LE
Y
L
E
A
S
N
G
D
M
K
L
I
L
A
A
R
R
L
E
K
L
E
E
L
K
K
T
I
-
D
Q
---
E
F
P
N
A
K
-
V
H
V
---
A
Q
L
D
I
T
Q
A
E
K
----
I
KPFI
E
N
L
P
----
Q
E
F
K
D
I
D
I
L
V
N
N
A
G
K
---
A
L
G
S
D
R
V
G
Q
I
A
T
E
D
I
Q
D
V
F
D
T
N
V
T
A
L
I
N
I
T
Q
A
V
L
P
I
--
F
Q
A
K
-
N
--
S
G
D
I
V
N
L
G
S
I
A
G
R
D
A
Y
P
T
G
--
S
I
Y
C
A
S
K
F
A
V
G
A
F
T
D
S
L
R
K
E
L
--
I
N
T
K
I
R
V
I
L
I
A
P
G
L
V
E
T
-
E
F
-
S
L
V
R
-----
Y
R
G
----
N
E---
E
---------
Q
A
K
N
V
Y
K
DT
T
P
--
L
M
A
D
D
V
A
D
L
I
V
Y
A
T
S
R
K
Q
N
T
V
-------------------------------
21
PsiBlast_CBE
74.28
35%
14
- C1 -
3RKU
1
YM71_YEAST
D:
[29-267]
-
E
R
L
A
K
K
T
V
L
I
T
G
A
S
A
G
I
G
K
A
T
A
LE
Y
L
E
A
S
N
G
D
M
K
L
I
L
A
A
R
R
L
E
K
L
E
E
L
K
K
T
I
-
D
Q
---
E
F
P
N
A
K
-
V
H
V
---
A
Q
L
D
I
T
Q
A
E
K
----
I
KPFI
E
N
L
P
----
Q
E
F
K
D
I
D
I
L
V
N
N
A
G
K
---
A
L
G
S
D
R
V
G
Q
I
A
T
E
D
I
Q
D
V
F
D
T
N
V
T
A
L
I
N
I
T
Q
A
V
L
P
I
--
F
Q
A
K
-
N
--
S
G
D
I
V
N
L
G
S
I
A
G
R
D
A
Y
P
T
G
--
S
I
Y
C
A
S
K
F
A
V
G
A
F
T
D
S
L
R
K
E
L
--
I
N
T
K
I
R
V
I
L
I
A
P
G
L
V
E
T
-
E
F
-
S
L
V
R
-----
Y
R
G
----
N
E---
E
---------
Q
A
K
N
V
Y
K
DT
T
P
--
L
M
A
D
D
V
A
D
L
I
V
Y
A
T
S
R
K
Q
N
T
V
-------------------------------
22
PsiBlast_CBE
73.82
35%
12
- C1 -
3RKU
1
YM71_YEAST
C:
[29-267]
-
E
R
L
A
K
K
T
V
L
I
T
G
A
S
A
G
I
G
K
A
T
A
LE
Y
L
E
A
S
N
G
D
M
K
L
I
L
A
A
R
R
L
E
K
L
E
E
L
K
K
T
I
-
D
Q
---
E
F
P
N
A
K
-
V
H
V
---
A
Q
L
D
I
T
Q
A
E
K
----
I
KPFI
E
N
L
P
----
Q
E
F
K
D
I
D
I
L
V
N
N
A
G
K
---
A
L
G
S
D
R
V
G
Q
I
A
T
E
D
I
Q
D
V
F
D
T
N
V
T
A
L
I
N
I
T
Q
A
V
L
P
I
--
F
Q
A
K
-
N
--
S
G
D
I
V
N
L
G
S
I
A
G
R
D
A
Y
P
T
G
--
S
I
Y
C
A
S
K
F
A
V
G
A
F
T
D
S
L
R
K
E
L
--
I
N
T
K
I
R
V
I
L
I
A
P
G
L
V
E
T
-
E
F
-
S
L
V
R
-----
Y
R
G
----
N
E---
E
---------
Q
A
K
N
V
Y
K
DT
T
P
--
L
M
A
D
D
V
A
D
L
I
V
Y
A
T
S
R
K
Q
N
T
V
-------------------------------
11
PsiBlast_PDB
73.63
33%
-96
- C1 -
3AI2
1
?
A:
[5-210]
---
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
--
E
G
F
A
K
E
G
-
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
---
K
F
-
G
V
R
-
V
L
E
---
V
A
V
D
V
A
T
P
E
G
V
D
A
V
V
----
E
S
V
R
----
S
S
F
G
G
A
D
I
L
V
N
N
A
G
T
---
G
S
-
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
--
M
R
A
R
-
G
--
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
--
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
-
I
K
T
A
K
E
L
T
K
D
N
G
----
G
----
D
---------
W
----------------------------------------------------------------
44
PsiBlast_CBE
73.21
33%
-92
- C1 -
3AI3
3
?
E:
[5-210]
---
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
--
E
G
F
A
K
E
G
-
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
---
K
F
-
G
V
R
-
V
L
E
---
V
A
V
D
V
A
T
P
E
G
VDAV
V
----
E
S
V
R
----
S
S
F
G
G
A
D
I
L
V
N
N
A
G
T
---
G
S
-
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
L
V
M
A
A
V
R
L
A
R
G
L
V
P
G
--
M
R
A
R
-
G
--
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
--
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
-
I
K
T
A
KELTK
D
N
G
----
G
----
D
---------
W
----------------------------------------------------------------
14
PsiBlast_PDB
73.03
33%
-96
- C1 -
3AI3
3
?
A:
[5-210]
---
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
--
E
G
F
A
K
E
G
-
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
---
K
F
-
G
V
R
-
V
L
E
---
V
A
V
D
V
A
T
P
E
G
V
D
A
V
V
----
E
S
V
R
----
S
S
F
G
G
A
D
I
L
V
N
N
A
G
T
---
G
S
-
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
L
V
M
A
A
V
R
L
A
R
G
L
V
P
G
--
M
R
A
R
-
G
--
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
--
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
-
I
K
T
A
K
E
L
T
K
D
N
G
----
G
----
D
---------
W
----------------------------------------------------------------
37
PsiBlast_CBE
72.99
33%
-95
- C1 -
3AI2
1
?
G:
[5-210]
---
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
--
E
G
F
A
K
E
G
-
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
---
K
F
-
G
V
R
-
V
L
E
---
V
A
V
D
V
A
T
P
E
G
VDAV
V
----
E
S
V
R
----
S
S
F
G
G
A
D
I
L
V
N
N
A
G
T
---
G
S
-
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
--
M
R
A
R
-
G
--
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
--
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
-
I
K
T
A
KELTK
D
N
G
----
G
----
D
---------
W
----------------------------------------------------------------
42
PsiBlast_CBE
72.60
33%
-94
- C1 -
3AI2
1
?
B:
[5-210]
---
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
--
E
G
F
A
K
E
G
-
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
---
K
F
-
G
V
R
-
V
L
E
---
V
A
V
D
V
A
T
P
E
G
VDAV
V
----
E
S
V
R
----
S
S
F
G
G
A
D
I
L
V
N
N
A
G
T
---
G
S
-
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
--
M
R
A
R
-
G
--
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
--
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
-
I
K
T
A
KELTK
D
N
G
----
G
----
D
---------
W
----------------------------------------------------------------
41
PsiBlast_CBE
72.51
33%
-96
- C1 -
3AI2
1
?
C:
[5-210]
---
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
--
E
G
F
A
K
E
G
-
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
---
K
F
-
G
V
R
-
V
L
E
---
V
A
V
D
V
A
T
P
E
G
VDAV
V
----
E
S
V
R
----
S
S
F
G
G
A
D
I
L
V
N
N
A
G
T
---
G
S
-
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
--
M
R
A
R
-
G
--
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
--
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
-
I
K
T
A
KELTK
D
N
G
----
G
----
D
---------
W
----------------------------------------------------------------
45
PsiBlast_CBE
72.15
33%
-94
- C1 -
3AI3
2
?
C:
[5-210]
---
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
--
E
G
F
A
K
E
G
-
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
---
K
F
-
G
V
R
-
V
L
E
---
V
A
V
D
V
A
T
P
E
G
VDAV
V
----
E
S
V
R
----
S
S
F
G
G
A
D
I
L
V
N
N
A
G
T
---
G
S
-
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
L
V
M
A
A
V
R
L
A
R
G
L
V
P
G
--
M
R
A
R
-
G
--
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
--
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
-
I
K
T
A
KELTK
D
N
G
----
G
----
D
---------
W
----------------------------------------------------------------
38
PsiBlast_CBE
71.84
33%
-96
- C1 -
3AI2
1
?
F:
[5-210]
---
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
--
E
G
F
A
K
E
G
-
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
---
K
F
-
G
V
R
-
V
L
E
---
V
A
V
D
V
A
T
P
E
G
VDAV
V
----
E
S
V
R
----
S
S
F
G
G
A
D
I
L
V
N
N
A
G
T
---
G
S
-
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
--
M
R
A
R
-
G
--
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
--
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
-
I
K
T
A
KELTK
D
N
G
----
G
----
D
---------
W
----------------------------------------------------------------
39
PsiBlast_CBE
71.76
33%
-94
- C1 -
3AI2
1
?
E:
[5-210]
---
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
--
E
G
F
A
K
E
G
-
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
---
K
F
-
G
V
R
-
V
L
E
---
V
A
V
D
V
A
T
P
E
G
VDAV
V
----
E
S
V
R
----
S
S
F
G
G
A
D
I
L
V
N
N
A
G
T
---
G
S
-
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
--
M
R
A
R
-
G
--
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
--
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
-
I
K
T
A
KELTK
D
N
G
----
G
----
D
---------
W
----------------------------------------------------------------
40
PsiBlast_CBE
71.73
33%
-97
- C1 -
3AI2
1
?
D:
[5-210]
---
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
--
E
G
F
A
K
E
G
-
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
---
K
F
-
G
V
R
-
V
L
E
---
V
A
V
D
V
A
T
P
E
G
VDAV
V
----
E
S
V
R
----
S
S
F
G
G
A
D
I
L
V
N
N
A
G
T
---
G
S
-
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
H
V
M
A
A
V
R
L
A
R
G
L
V
P
G
--
M
R
A
R
-
G
--
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
--
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
-
I
K
T
A
KELTK
D
N
G
----
G
----
D
---------
W
----------------------------------------------------------------
118
HHSearch
71.03
26%
-71
- C1 -
1CYD
2
CBR2_MOUSE
A:
[3-227]
-
L
N
F
S
G
L
R
A
L
V
T
G
A
G
K
G
I
G
R
D
T
V
--
K
A
L
H
A
S
G
-
A
K
V
V
A
V
T
R
T
N
S
D
L
V
S
L
A
K
E
C
----------
P
G
-
I
E
P
---
V
C
V
D
L
G
D
W
D
A
----
T
----
E
K
A
L
----
G
G
I
G
P
V
D
L
L
V
N
N
A
A
L
---
V
I
-
M
Q
P
F
L
E
V
T
K
E
A
F
D
R
S
F
S
V
N
L
R
S
V
F
Q
V
S
Q
M
V
A
R
D
--
M
I
N
R
G
V
--
P
G
S
I
V
N
V
S
S
M
V
A
H
V
T
F
P
N
L
--
I
T
Y
S
S
T
K
G
A
M
T
M
L
T
K
A
M
A
M
E
L
--
G
P
H
K
I
R
V
N
S
V
N
P
T
V
V
L
T
-
D
M
-
G
K
K
V
-----
S
A
D
P
---
E
F
A
R
K
L
---------
K
E
R
H
P
L
R
--
K
F
--
A
E
V
E
D
V
V
N
S
I
L
F
L
L
S
D
R
S
----------------------------------
85
PsiBlast_CBE
70.81
34%
-81
* C1 *
2JAP
2
?
D:
[5-192]
---
L
Q
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
--
R
A
L
A
A
E
G
-
A
A
V
A
I
A
A
R
R
V
E
K
L
R
A
L
G
D
E
L
-
T
A
---
A
G
-
A
-
K
-
V
H
V
---
L
E
L
D
V
A
D
R
Q
G
----
V
DAAV
A
S
T
V
----
E
A
L
G
G
L
D
I
L
V
N
N
A
G
I
---
M
L
-
L
G
P
V
E
D
A
D
T
T
D
W
T
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
R
A
A
L
P
H
--
L
L
-
R
-
S
--
K
G
T
V
V
Q
M
S
S
I
A
G
R
V
N
V
R
N
A
--
A
V
Y
Q
A
T
K
F
G
V
N
A
F
S
E
T
L
R
Q
E
V
--
T
E
R
G
V
R
V
V
V
I
E
P
G
T
T
D
T
-
E
L
-------------------------------------------------------------------------------------------------
43
PsiBlast_CBE
70.28
33%
-96
- C1 -
3AI3
4
?
G:
[5-210]
---
I
S
G
K
V
A
V
I
T
G
S
S
S
G
I
G
L
A
I
A
--
E
G
F
A
K
E
G
-
A
H
I
V
L
V
A
R
Q
V
D
R
L
H
E
A
A
R
S
L
-
K
E
---
K
F
-
G
V
R
-
V
L
E
---
V
A
V
D
V
A
T
P
E
G
VDAV
V
----
E
S
V
R
----
S
S
F
G
G
A
D
I
L
V
N
N
A
G
T
---
G
S
-
N
E
T
I
M
E
A
A
D
E
K
W
Q
F
Y
W
E
L
L
V
M
A
A
V
R
L
A
R
G
L
V
P
G
--
M
R
A
R
-
G
--
G
G
A
I
I
H
N
A
S
I
C
A
V
Q
P
L
W
Y
E
--
P
I
Y
N
V
T
K
A
A
L
M
M
F
S
K
T
L
A
T
E
V
--
I
K
D
N
I
R
V
N
C
I
N
P
G
L
I
L
T
P
D
W
-
I
K
T
A
KELTK
D
N
G
----
G
----
D
---------
W
----------------------------------------------------------------
87
PsiBlast_CBE
70.24
34%
-82
- C1 -
2JAP
2
?
B:
[5-192]
---
L
Q
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
--
R
A
L
A
A
E
G
-
A
A
V
A
I
A
A
R
R
V
E
K
L
R
A
L
G
D
E
L
-
T
A
---
A
G
-
A
-
K
-
V
H
V
---
L
E
L
D
V
A
D
R
Q
G
----
V
D
A
A
V
A
S
T
V
----
E
A
L
G
G
L
D
I
L
V
N
N
A
G
I
---
M
L
-
L
G
P
V
E
D
A
D
T
T
D
W
T
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
R
A
A
L
P
H
--
L
L
-
R
-
S
--
K
G
T
V
V
Q
M
S
S
I
A
G
R
V
N
V
R
N
A
--
A
V
Y
Q
A
T
K
F
G
V
N
A
F
S
E
T
L
R
Q
E
V
--
T
E
R
G
V
R
V
V
V
I
E
P
G
T
T
D
T
-
E
L
-------------------------------------------------------------------------------------------------
88
PsiBlast_CBE
68.67
34%
-82
- C1 -
2JAP
2
?
A:
[5-192]
---
L
Q
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
--
R
A
L
A
A
E
G
-
A
A
V
A
I
A
A
R
R
V
E
K
L
R
A
L
G
D
E
L
-
T
A
---
A
G
-
A
-
K
-
V
H
V
---
L
E
L
D
V
A
D
R
Q
G
----
V
D
A
A
V
A
S
T
V
----
E
A
L
G
G
L
D
I
L
V
N
N
A
G
I
---
M
L
-
L
G
P
V
E
D
A
D
T
T
D
W
T
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
R
A
A
L
P
H
--
L
L
-
R
-
S
--
K
G
T
V
V
Q
M
S
S
I
A
G
R
V
N
V
R
N
A
--
A
V
Y
Q
A
T
K
F
G
V
N
A
F
S
E
T
L
R
Q
E
V
--
T
E
R
G
V
R
V
V
V
I
E
P
G
T
T
D
T
-
E
L
-------------------------------------------------------------------------------------------------
86
PsiBlast_CBE
67.01
34%
-81
- C1 -
2JAP
2
?
C:
[5-192]
---
L
Q
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
--
R
A
L
A
A
E
G
-
A
A
V
A
I
A
A
R
R
V
E
K
L
R
A
L
G
D
E
L
-
T
A
---
A
G
-
A
-
K
-
V
H
V
---
L
E
L
D
V
A
D
R
Q
G
----
V
DAAV
A
S
T
V
----
E
A
L
G
G
L
D
I
L
V
N
N
A
G
I
---
M
L
-
L
G
P
V
E
D
A
D
T
T
D
W
T
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
R
A
A
L
P
H
--
L
L
-
R
-
S
--
K
G
T
V
V
Q
M
S
S
I
A
G
R
V
N
V
R
N
A
--
A
V
Y
Q
A
T
K
F
G
V
N
A
F
S
E
T
L
R
Q
E
V
--
T
E
R
G
V
R
V
V
V
I
E
P
G
T
T
D
T
-
E
L
-------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
64.70
34%
-92
- C1 -
3P19
1
?
A:
[17-198]
------
K
L
V
V
I
T
G
A
S
S
G
I
G
E
A
I
A
--
R
R
F
S
E
E
G
-
H
P
L
L
L
L
A
R
R
V
E
R
L
K
A
L
N
--
L
-
P
N
---
T
L
-
C
A
Q
-
V
D
V
TD
K
Y
T
F
D
T
A
--------
I
----
T
R
A
E
----
K
I
Y
G
P
A
D
A
I
V
N
N
A
G
M
---
M
L
-
L
G
Q
I
D
T
Q
E
A
N
E
W
Q
R
M
F
D
V
N
V
L
G
L
L
N
G
M
Q
A
V
L
A
P
--
M
K
A
R
-
N
--
C
G
T
I
I
N
I
S
S
I
A
G
K
K
T
F
P
D
H
--
A
A
Y
C
G
T
K
F
A
V
H
A
I
S
E
N
V
R
E
E
V
--
A
A
S
N
V
R
V
M
T
I
A
P
S
A
V
K
T
-
E
L
-
L
S
----------------------------------------------------------------------------------------------
30
PsiBlast_CBE
64.09
34%
-13
- C1 -
1XG5
2
DHR11_HUMAN
C:
[37-263]
----------
V
T
G
A
S
G
G
I
G
A
A
V
A
--
R
A
L
V
Q
Q
G
-
L
K
V
V
G
C
A
R
T
V
G
N
I
E
E
L
A
A
E
C
K
S
A
---
G
Y
-
P
G
T
-
L
I
P
---
Y
R
C
D
L
S
N
E
E
D
----
I
LSMF
S
A
I
R
----
S
Q
H
S
G
V
D
I
C
I
N
N
A
G
L
---
A
R
-
P
D
T
L
L
S
G
S
T
S
G
W
K
D
M
F
N
V
N
V
L
A
L
S
I
C
T
R
E
A
Y
Q
S
--
M
K
E
R
-
N
VD
D
G
H
I
I
N
I
N
S
M
S
G
H
R
V
L
P
L
S
VT
H
F
Y
S
A
T
K
Y
A
V
T
A
L
T
E
G
L
R
Q
E
L
RE
A
Q
T
H
I
R
A
T
C
I
S
P
G
V
V
E
T
-
Q
F
A
F
K
L
H
-----
D
K
D
----
P
----
E
---------
K
A
A
A
T
Y
E
--
Q
M
KC
L
K
P
E
D
V
A
E
A
V
I
Y
V
L
S
T
------------------------------------
32
PsiBlast_CBE
62.11
34%
-91
- C1 -
3P19
1
?
D:
[17-198]
------
K
L
V
V
I
T
G
A
S
S
G
I
G
E
A
I
A
--
R
R
F
S
E
E
G
-
H
P
L
L
L
L
A
R
R
V
E
R
L
K
A
L
N
--
L
-
P
N
---
T
L
-
C
A
Q
-
V
D
V
TDK
Y
T
F
D
T
A
--------
I
----
T
R
A
E
----
K
I
Y
G
P
A
D
A
I
V
N
N
A
G
M
---
M
L
-
L
G
Q
I
D
T
Q
E
A
N
E
W
Q
R
M
F
D
V
N
V
L
G
L
L
N
G
M
Q
A
V
L
A
P
--
M
K
A
R
-
N
--
C
G
T
I
I
N
I
S
S
I
A
G
K
K
T
F
P
D
H
--
A
A
Y
C
G
T
K
F
A
V
H
A
I
S
E
N
V
R
E
E
V
--
A
A
S
N
V
R
V
M
T
I
A
P
S
A
V
K
T
-
E
L
-
L
S
----------------------------------------------------------------------------------------------
31
PsiBlast_CBE
59.86
34%
-28
- C1 -
1XG5
1
DHR11_HUMAN
B:
[37-263]
----------
V
T
G
A
S
G
G
I
G
A
A
V
A
--
R
A
L
V
Q
Q
G
-
L
K
V
V
G
C
A
R
T
V
G
N
I
E
E
L
A
A
E
C
K
S
A
---
G
Y
-
P
G
T
-
L
I
P
---
Y
R
C
D
L
S
N
E
E
D
----
I
LSMF
S
A
I
R
----
S
Q
H
S
G
V
D
I
C
I
N
N
A
G
L
---
A
R
-
P
D
T
L
L
S
G
S
T
S
G
W
K
D
M
F
N
V
N
V
L
A
L
S
I
C
T
R
E
A
Y
Q
S
--
M
K
E
R
-
N
VD
D
G
H
I
I
N
I
N
S
M
S
G
H
R
V
L
P
L
S
VT
H
F
Y
S
A
T
K
Y
A
V
T
A
L
T
E
G
L
R
Q
E
L
RE
A
Q
T
H
I
R
A
T
C
I
S
P
G
V
V
E
T
-
Q
F
A
F
K
L
H
-------------------------------------
M
KC
L
K
P
E
D
V
A
E
A
V
I
Y
V
L
S
T
------------------------------------
75
PsiBlast_CBE
48.90
36%
-39
- C1 -
3RI3
3
ACT3_STRCO
B:
[31-220]
----------
V
T
G
A
T
S
G
I
G
L
E
I
A
--
R
R
L
G
K
E
G
-
L
R
V
F
V
C
A
R
G
E
E
G
L
R
T
T
L
K
E
L
-
R
E
A
GV
E
A
-
D
G
R
T
C
D
V
-----
R
S
V
P
E
I
E
A
L
---
V
----
A
A
V
V
----
E
R
Y
G
P
V
D
V
L
V
N
N
A
G
R
L
G
G
G
A
-
T
A
E
L
A
D
E
L
W
L
D
V
---
V
E
T
N
L
T
G
V
F
R
V
T
K
Q
V
L
K
A
GG
M
L
E
R
-
G
--
T
G
R
I
V
N
I
A
S
T
G
G
K
Q
G
V
V
H
A
--
A
P
Y
S
A
S
K
H
G
V
V
G
F
T
K
A
L
G
L
E
L
--
A
R
T
G
I
T
V
N
A
V
C
P
G
F
V
E
T
----------------------------------------------------------------------------------------------------
79
PsiBlast_CBE
47.71
36%
-39
- C1 -
3CSD
3
ACT3_STRCO
B:
[31-220]
----------
V
T
G
A
T
S
G
I
G
L
E
I
A
--
R
R
L
G
K
E
G
-
L
R
V
F
V
C
A
R
G
E
E
G
L
R
T
T
L
K
E
L
-
R
E
A
GV
E
A
-
D
G
R
T
C
D
V
-----
R
S
V
P
E
I
E
A
L
---
V
----
A
A
V
V
----
E
R
Y
G
P
V
D
V
L
V
N
N
A
G
R
L
G
G
G
A
-
T
A
E
L
A
D
E
L
W
L
D
V
---
V
E
T
N
L
T
G
V
F
R
V
T
K
Q
V
L
K
A
GG
M
L
E
R
-
G
--
T
G
R
I
V
N
I
A
S
T
G
G
K
Q
G
V
V
H
A
--
A
P
Y
S
A
S
K
H
G
V
V
G
F
T
K
A
L
G
L
E
L
--
A
R
T
G
I
T
V
N
A
V
C
P
G
F
V
E
T
----------------------------------------------------------------------------------------------------
62
PsiBlast_CBE
47.33
36%
-36
- C1 -
1XR3
2
ACT3_STRCO
A:
[11-192]
----------
V
T
G
A
T
S
G
I
G
L
E
I
A
--
R
R
L
G
K
E
G
-
L
R
V
F
V
C
A
R
G
E
E
G
L
R
T
T
L
K
E
L
-
R
E
A
GV
E
A
-
D
G
R
T
C
D
V
-----
R
S
V
P
E
I
E
A
L
---
V
----
A
A
V
V
----
E
R
Y
G
P
V
D
V
L
V
N
N
A
G
R
P
G
G
G
A
-
T
A
E
L
A
D
E
L
W
L
D
V
---
V
E
T
N
L
T
G
V
F
R
V
T
K
Q
V
L
K
A
GG
M
L
E
R
-
G
--
T
G
R
I
V
N
I
A
S
T
G
G
K
Q
G
V
V
H
A
--
A
P
Y
S
A
S
K
H
G
V
V
G
F
T
K
A
L
G
L
E
L
--
A
R
T
G
I
T
V
N
A
V
C
P
G
F
V
E
T
----------------------------------------------------------------------------------------------------
72
PsiBlast_CBE
46.85
36%
-41
- C1 -
2RHR
3
ACT3_STRCO
A:
[27-208]
----------
V
T
G
A
T
S
G
I
G
L
E
I
A
--
R
R
L
G
K
E
G
-
L
R
V
F
V
C
A
R
G
E
E
G
L
R
T
T
L
K
E
L
-
R
E
A
GV
E
A
-
D
G
R
T
C
D
V
-----
R
S
V
P
E
I
E
A
L
---
V
----
A
A
V
V
----
E
R
Y
G
P
V
D
V
L
V
N
N
A
G
R
L
G
G
G
A
-
T
A
E
L
A
D
E
L
W
L
D
V
---
V
E
T
N
L
T
G
V
F
R
V
T
K
Q
V
L
K
A
GG
M
L
E
R
-
G
--
T
G
R
I
V
N
I
A
S
T
G
G
K
Q
G
V
V
H
A
--
A
P
Y
S
A
S
K
H
G
V
V
G
F
T
K
A
L
G
L
E
L
--
A
R
T
G
I
T
V
N
A
V
C
P
G
F
V
E
T
----------------------------------------------------------------------------------------------------
76
PsiBlast_CBE
45.78
36%
-34
- C1 -
3RI3
3
ACT3_STRCO
A:
[31-212]
----------
V
T
G
A
T
S
G
I
G
L
E
I
A
--
R
R
L
G
K
E
G
-
L
R
V
F
V
C
A
R
G
E
E
G
L
R
T
T
L
K
E
L
-
R
E
A
GV
E
A
-
D
G
R
T
C
D
V
-----
R
S
V
P
E
I
E
A
L
---
V
----
A
A
V
V
----
E
R
Y
G
P
V
D
V
L
V
N
N
A
G
R
L
G
G
G
A
-
T
A
E
L
A
D
E
L
W
L
D
V
---
V
E
T
N
L
T
G
V
F
R
V
T
K
Q
V
L
K
A
GG
M
L
E
R
-
G
--
T
G
R
I
V
N
I
A
S
T
G
G
K
Q
G
V
V
H
A
--
A
P
Y
S
A
S
K
H
G
V
V
G
F
T
K
A
L
G
L
E
L
--
A
R
T
G
I
T
V
N
A
V
C
P
G
F
V
E
T
----------------------------------------------------------------------------------------------------