@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu40920: (2016-08-08 )
MALTAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVEVPDDRLQKLTELVNPKKTVPTAFEFTDIAGIVKGASKGEGLGNKFLSHIRQVDAICHVVRAFSDDNITHVSGKVDPIDDIETINLELILADMETVEKRITRVSKLAKQKDKDAVFEFEILSKLKEAFESEKPARSVEFTEEQQKLVKQLHLLTSKPILYVANVSEDEVADPSGNENVAKIREYAAGENAEVIVVCAKIESEIAELEGEEKQMFLEELGIQESGLDQLIKASYSLLGLATYFTAGEQEVRAWTFKKGMKAPECAGIIHSDFERGFIRAETVAYEDLLAGGGMAGAKEAGKVRLEGKEYVVQDGDVIHFRFNV
Atome Classification :
(21 SA)
-------.........10........20.....-.-..30........40....-....50....------....----60........70........80...--...---..90....-....100.......110.......120.......130.......140.......-150.----------.------.....160-...--------.....170..-......-----180.....-..190.......200........210......-.220.......230-.......--.240........250.......260-....-------...270--------........280.......290----.....-----.-.300.......310.......320.......330.......340.......350.......360....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------MALTAGIVGLPNV
G
K
S
T
L
F
N
A
I
T
QAG-A-ESANY
P
F
C
T
IDPNV
G
I
V
E-V
P
D
D
R
L
Q
K
L
T
------
E
LVN----PKKTVP
T
A
F
E
F
T
D
I
A
G
I
VKGASKGE--
G
L
G
---
N
K
F
L
S
H
I
R
-
Q
V
D
A
I
C
H
V
V
R
A
FSDDN
I
T
HVSGKVDPIDD
I
E
T
I
N
L
E
L
I
LA
D
M
E
T
V
E
K
R
I
T
R
V
S
K
-
L
A
KQ----------K------DK
D
A
V
F
E
--
F
E
I
--------
L
S
K
L
K
E
A
-
F
E-SEKPAR-----SVEF
T
E
E
Q
-
Q
K
L
V
K
Q
L
H
L
LTSK
P
-
I
L
Y
V
A
NVSEDEVADPSG-N
E
N
V
A
K
I
R
E
Y
AAG--ENA
E
V
I
V
--
V
C
-
A
K
I
E
S
E
I
A
ELE
G
E
E
K
Q
M
F
L
E
E
L-GIQ
E
-------
S
G
L
D
Q
---------
L
I
K
A
S
Y
S
L
L
G
L
A
T
Y
FTAGE
Q
E
----
V
R
A
W
T
-----
F
-KKGMKA
P
E
C
A
G
I
I
H
S
D
F
ERGF
I
R
A
E
T
V
A
Y
E
D
L
LAGGGMAGAKEA
G
K
V
R
LEG
K
E
Y
V
VQDG
D
V
I
H
F
R
FNV
1
PsiBlast_PDB
85.40
58%
-112
- C1 -
1JAL
-
YCHF_HAEIN
A:
[1-363]
-------
M
G
F
K
C
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
K
A
G
--------
P
F
C
T
I
E
P
N
T
G
V
V
P
-
M
P
D
P
R
L
D
A
L
A
------
E
I
V
K
----
P
E
R
I
L
P
T
T
M
E
F
V
D
I
A
G
L
V
A
G
A
S
K
G
E
--
G
L
G
---
N
K
F
L
A
N
I
R
-
E
T
D
A
I
G
H
V
V
R
C
F
E
N
---------
I
D
P
L
D
D
I
D
T
I
N
T
E
L
A
L
A
D
L
D
S
C
E
R
A
I
Q
R
L
Q
K
-
R
A
K
G
----------
G
------
D
K
E
A
K
F
E
--
L
S
V
--------
M
E
K
I
L
P
V
-
L
E
-
N
A
G
M
I
R
-----
S
V
G
L
D
K
E
E
-
L
Q
A
I
K
S
Y
N
F
L
T
L
K
P
-
T
M
Y
I
A
N
V
N
E
D
G
F
E
N
----
N
P
Y
L
D
R
V
R
E
I
A
A
K
--
E
G
A
V
V
V
P
--
V
C
-
A
A
I
E
S
E
I
A
E
L
D
D
E
E
K
V
E
F
L
Q
D
L
-
G
I
E
E
-------
P
G
L
N
R
---------
V
I
R
A
G
Y
A
L
L
N
L
Q
T
Y
F
T
A
G
V
K
E
----
V
R
A
W
T
-----
V
-
S
V
G
A
T
A
P
K
A
A
A
V
I
H
T
D
F
E
K
G
F
I
R
A
E
V
I
A
Y
E
D
F
I
Q
F
N
G
E
N
G
A
K
E
A
G
K
W
R
L
E
G
K
D
Y
I
V
Q
D
G
D
V
M
H
F
R
F
N
V
64
HHSearch
77.08
57%
-48
- C1 -
1JAL
-
YCHF_HAEIN
A:
[2-363]
--------
G
F
K
C
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
K
A
G
--------
P
F
C
T
I
E
P
N
T
G
V
V
P
-
M
P
D
P
R
L
D
A
L
A
------
E
I
V
K
----
P
E
R
I
L
P
T
T
M
E
F
V
D
I
A
G
L
V
A
G
A
S
K
G
E
--
G
L
G
---
N
K
F
L
A
N
I
R
-
E
T
D
A
I
G
H
V
V
R
C
F
E
N
---------
I
D
P
L
D
D
I
D
T
I
N
T
E
L
A
L
A
D
L
D
S
C
E
R
A
I
Q
R
L
Q
K
-
R
A
K
G
----------
G
D-----
K
E
A
K
F
E
L
--
S
V
M
--------
E
K
I
L
-
P
V
-
L
E
-
N
A
G
M
I
R
-----
S
V
G
L
D
K
E
E
-
L
Q
A
I
K
S
Y
N
F
L
T
L
K
P
-
T
M
Y
I
A
N
V
N
E
D
G
F
E
N
-
N
---
P
Y
L
D
R
V
R
E
I
A
A
K
--
E
G
A
V
V
V
P
--
V
C
-
A
A
I
E
S
E
I
A
E
L
D
D
E
E
K
V
E
F
L
Q
D
L
-
G
I
E
E
-------
P
G
L
N
R
---------
V
I
R
A
G
Y
A
L
L
N
L
Q
T
Y
F
T
A
G
V
K
E
----
V
R
A
W
T
-----
V
-
S
V
G
A
T
A
P
K
A
A
A
V
I
H
T
D
F
E
K
G
F
I
R
A
E
V
I
A
Y
E
D
F
I
Q
F
N
G
E
N
G
A
K
E
A
G
K
W
R
L
E
G
K
D
Y
I
V
Q
D
G
D
V
M
H
F
R
F
N
V
63
HHSearch
76.47
53%
-8
- C1 -
2DBY
4
?
A:
[1-366]
--------
M
L
A
V
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
R
A
N
-
A
-
L
A
A
N
Y
P
F
A
T
I
D
K
N
V
G
V
V
P
-
L
E
D
E
R
L
Y
A
L
Q
------
R
T
F
A
KGE
R
V
P
P
V
V
P
T
H
V
E
F
V
D
I
A
G
L
V
K
G
A
H
K
G
E
--
G
L
G
---
N
Q
F
L
A
H
I
R
-
E
V
A
A
I
A
H
V
L
R
C
F
P
D
P
-----------
L
E
D
A
E
V
V
E
T
E
L
L
L
A
D
L
A
T
L
E
R
R
L
E
R
L
R
K
-
E
A
R
A
----------
D
-------
R
E
R
L
P
L
--
L
E
A
--------
A
E
G
L
Y
V
H
-
L
Q
-
E
G
K
P
A
R
-----
T
F
P
P
S
E
A
V
-
A
R
F
L
K
E
T
P
L
L
T
A
K
P
-
V
I
Y
V
A
N
V
A
E
E
D
L
P
D
-
G
R
G
N
P
Q
V
E
A
V
R
R
K
A
L
E
--
E
G
A
E
V
V
V
--
V
S
-
A
R
L
E
A
E
L
A
E
L
S
G
E
E
A
R
E
L
L
A
A
Y
-
G
L
Q
E
-------
S
G
L
Q
R
---------
L
A
R
A
G
Y
R
A
L
D
L
L
T
F
F
T
A
G
E
K
E
----
V
R
A
W
T
-----
V
-
R
R
G
T
K
A
P
R
A
A
G
E
I
H
S
D
M
E
R
G
F
I
R
A
E
V
I
P
W
D
K
L
V
E
A
G
G
W
A
R
A
K
E
R
G
W
V
R
L
E
G
K
D
Y
E
V
Q
D
G
D
V
I
Y
V
L
F
--
22
PsiBlast_CBE
75.12
43%
-57
- C1 -
5EE3
5
?
B:
[26-388]
---------
L
K
I
G
I
V
G
L
P
N
V
G
K
S
T
F
F
N
I
V
T
K
L
S
-
I
-
P
A
E
N
F
P
F
C
T
I
D
P
N
E
A
R
V
Y
-
V
P
D
E
R
F
D
W
L
C
------
Q
L
Y
K
----
P
K
S
E
V
S
A
Y
L
E
I
N
D
I
A
G
L
V
R
----
G
E
--
G
L
G
---
N
A
F
L
S
H
I
R
-
A
V
D
G
I
F
H
V
L
R
A
F
E
D
K
------
D
S
V
D
P
V
R
D
L
E
T
I
G
E
E
L
R
L
K
D
I
E
F
V
Q
N
K
I
D
D
L
E
K
S
M
K
R
S
----------
N
------
D
K
Q
L
K
L
E
--
H
E
L
--------
C
E
K
V
K
A
H
-
L
E
-
D
G
K
D
V
R
-----
F
G
D
W
K
S
A
D
-
I
E
I
L
N
T
F
Q
L
L
T
A
K
P
-
V
V
Y
L
V
N
M
S
E
K
D
Y
Q
R
-
K
K
-
N
K
F
L
P
K
I
H
A
W
V
Q
E
--
H
G
G
E
T
I
I
P
F
S
C
-
A
-
F
E
R
L
L
A
D
M
P
P
D
E
A
A
K
Y
C
A
E
N
-
Q
I
A
--------
S
V
I
P
K
---------
I
I
K
T
G
F
A
A
I
H
L
I
Y
F
F
T
A
G
P
D
E
----
V
K
C
W
Q
-----
I
-
R
R
Q
T
K
A
P
Q
A
A
G
T
I
H
T
D
F
E
R
G
F
I
C
A
E
V
M
K
F
D
D
L
K
E
L
G
S
E
S
A
V
K
A
A
G
K
Y
R
Q
E
G
K
T
Y
V
V
Q
D
G
D
I
I
F
F
K
F
N
-
4
PsiBlast_PDB
74.41
43%
-54
- C1 -
5EE1
-
?
A:
[25-387]
---------
L
K
I
G
I
V
G
L
P
N
V
G
K
S
T
F
F
N
I
V
T
K
L
S
-
I
-
P
A
E
N
F
P
F
C
T
I
D
P
N
E
A
R
V
Y
-
V
P
D
E
R
F
D
W
L
C
------
Q
L
Y
K
----
P
K
S
E
V
S
A
Y
L
E
I
N
D
I
A
G
L
V
R
--
H
A
G
E
--
G
L
G
---
N
A
F
L
S
H
I
R
-
A
V
D
G
I
F
H
V
L
R
A
F
E
D
--------
S
V
D
P
V
R
D
L
E
T
I
G
E
E
L
R
L
K
D
I
E
F
V
Q
N
K
I
D
D
L
E
K
S
M
K
R
S
----------
N
------
D
K
Q
L
K
L
E
--
H
E
L
--------
C
E
K
V
K
A
H
-
L
E
-
D
G
K
D
V
R
-----
F
G
D
W
K
S
A
D
-
I
E
I
L
N
T
F
Q
L
L
T
A
K
P
-
V
V
Y
L
V
N
M
S
E
K
D
Y
Q
R
-
K
K
-
N
K
F
L
P
K
I
H
A
W
V
Q
E
--
H
G
G
E
T
I
I
P
F
S
C
-
A
-
F
E
R
L
L
A
D
M
P
P
D
E
A
A
K
Y
C
A
E
N
-
Q
I
A
--------
S
V
I
P
K
---------
I
I
K
T
G
F
A
A
I
H
L
I
Y
F
F
T
A
G
P
D
E
----
V
K
C
W
Q
-----
I
-
R
R
Q
T
K
A
P
Q
A
A
G
T
I
H
T
D
F
E
R
G
F
I
C
A
E
V
M
K
F
D
D
L
K
E
L
G
S
E
S
A
V
K
A
A
G
K
Y
R
Q
E
G
K
T
Y
V
V
Q
D
G
D
I
I
F
F
K
F
N
-
5
PsiBlast_PDB
73.92
43%
-54
- C1 -
5EE3
5
?
A:
[26-388]
---------
L
K
I
G
I
V
G
L
P
N
V
G
K
S
T
F
F
N
I
V
T
K
L
S
-
I
-
P
A
E
N
F
P
F
C
T
I
D
P
N
E
A
R
V
Y
-
V
P
D
E
R
F
D
W
L
C
------
Q
L
Y
K
----
P
K
S
E
V
S
A
Y
L
E
I
N
D
I
A
-------------
L
G
---
N
A
F
L
S
H
I
R
-
A
V
D
G
I
F
H
V
L
R
A
F
E
D
K
------
D
S
V
D
P
V
R
D
L
E
T
I
G
E
E
L
R
L
K
D
I
E
F
V
Q
N
K
I
D
D
L
E
K
S
M
K
R
S
----------
N
------
D
K
Q
L
K
L
E
--
H
E
L
--------
C
E
K
V
K
A
H
-
L
E
-
D
G
K
D
V
R
-----
F
G
D
W
K
S
A
D
-
I
E
I
L
N
T
F
Q
L
L
T
A
K
P
-
V
V
Y
L
V
N
M
S
E
K
D
Y
Q
R
-
K
K
-
N
K
F
L
P
K
I
H
A
W
V
Q
E
--
H
G
G
E
T
I
I
P
F
S
C
-
A
-
F
E
R
L
L
A
D
M
P
P
D
E
A
A
K
Y
C
A
E
N
-
Q
I
A
--------
S
V
I
P
K
---------
I
I
K
T
G
F
A
A
I
H
L
I
Y
F
F
T
A
G
P
D
E
----
V
K
C
W
Q
-----
I
-
R
R
Q
T
K
A
P
Q
A
A
G
T
I
H
T
D
F
E
R
G
F
I
C
A
E
V
M
K
F
D
D
L
K
E
L
G
S
E
S
A
V
K
A
A
G
K
Y
R
Q
E
G
K
T
Y
V
V
Q
D
G
D
I
I
F
F
K
F
N
-
21
PsiBlast_CBE
73.60
43%
-55
- C1 -
5EE9
2
?
B:
[26-388]
---------
L
K
I
G
I
V
G
L
P
N
V
G
K
S
T
F
F
N
I
V
T
K
L
S
-
I
-
P
A
E
N
F
P
F
C
T
I
D
P
N
E
A
R
V
Y
-
V
P
D
E
R
F
D
W
L
C
------
Q
L
Y
K
----
P
K
S
E
V
S
A
Y
L
E
I
N
D
I
A
G
L
V
R
---------
L
G
---
N
A
F
L
S
H
I
R
-
A
V
D
G
I
F
H
V
L
R
A
F
E
D
--------
S
V
D
P
V
R
D
L
E
T
I
G
E
E
L
R
L
K
D
I
E
F
V
Q
N
K
I
D
D
L
E
K
S
M
K
R
S
----------
N
------
D
K
Q
L
K
L
E
--
H
E
L
--------
C
E
K
V
K
A
H
-
L
E
-
D
G
K
D
V
R
-----
F
G
D
W
K
S
A
D
-
I
E
I
L
N
T
F
Q
L
L
T
A
K
P
-
V
V
Y
L
V
N
M
S
E
K
D
Y
Q
R
-
K
K
-
N
K
F
L
P
K
I
H
A
W
V
Q
E
--
H
G
G
E
T
I
I
P
F
S
C
-
A
-
F
E
R
L
L
A
D
M
P
P
D
E
A
A
K
Y
C
A
E
N
-
Q
I
A
--------
S
V
I
P
K
---------
I
I
K
T
G
F
A
A
I
H
L
I
Y
F
F
T
A
G
P
D
E
----
V
K
C
W
Q
-----
I
-
R
R
Q
T
K
A
P
Q
A
A
G
T
I
H
T
D
F
E
R
G
F
I
C
A
E
V
M
K
F
D
D
L
K
E
L
G
S
E
S
A
V
K
A
A
G
K
Y
R
Q
E
G
K
T
Y
V
V
Q
D
G
D
I
I
F
F
K
F
N
-
6
PsiBlast_PDB
73.42
43%
-58
- C1 -
5EE9
2
?
A:
[26-388]
---------
L
K
I
G
I
V
G
L
P
N
V
G
K
S
T
F
F
N
I
V
T
K
L
S
-
I
-
P
A
E
N
F
P
F
C
T
I
D
P
N
E
A
R
V
Y
-
V
P
D
E
R
F
D
W
L
C
------
Q
L
Y
K
----
P
K
S
E
V
S
A
Y
L
E
I
N
D
I
A
G
L
V
R
--------------
N
A
F
L
S
H
I
R
-
A
V
D
G
I
F
H
V
L
R
A
F
E
D
--------
S
V
D
P
V
R
D
L
E
T
I
G
E
E
L
R
L
K
D
I
E
F
V
Q
N
K
I
D
D
L
E
K
S
M
K
R
S
----------
N
------
D
K
Q
L
K
L
E
--
H
E
L
--------
C
E
K
V
K
A
H
-
L
E
-
D
G
K
D
V
R
-----
F
G
D
W
K
S
A
D
-
I
E
I
L
N
T
F
Q
L
L
T
A
K
P
-
V
V
Y
L
V
N
M
S
E
K
D
Y
Q
R
-
K
K
-
N
K
F
L
P
K
I
H
A
W
V
Q
E
--
H
G
G
E
T
I
I
P
F
S
C
-
A
-
F
E
R
L
L
A
D
M
P
P
D
E
A
A
K
Y
C
A
E
N
-
Q
I
A
--------
S
V
I
P
K
---------
I
I
K
T
G
F
A
A
I
H
L
I
Y
F
F
T
A
G
P
D
E
----
V
K
C
W
Q
-----
I
-
R
R
Q
T
K
A
P
Q
A
A
G
T
I
H
T
D
F
E
R
G
F
I
C
A
E
V
M
K
F
D
D
L
K
E
L
G
S
E
S
A
V
K
A
A
G
K
Y
R
Q
E
G
K
T
Y
V
V
Q
D
G
D
I
I
F
F
K
F
N
-
3
PsiBlast_PDB
72.42
53%
25
- C1 -
2DBY
4
?
A:
[2-366]
---------
L
A
V
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
R
A
N
-
A
-
L
A
A
N
Y
P
F
A
T
I
D
K
N
V
G
V
V
P
-
L
E
D
E
R
L
Y
A
L
Q
R
T
F
AKG
E
R
V
P
----
P
--
V
V
P
T
H
V
E
F
V
D
I
A
G
L
V
K
G
A
H
K
G
E
--
G
L
G
---
N
Q
F
L
A
H
I
R
-
E
V
A
A
I
A
H
V
L
R
C
F
P
D
P
-----------
L
E
D
A
E
V
V
E
T
E
L
L
L
A
D
L
A
T
L
E
R
R
L
E
R
L
R
K
-
E
A
R
A
-----------------
D
R
E
R
L
P
L
--
L
E
A
--------
A
E
G
L
Y
V
H
-
L
Q
-
E
G
K
P
A
R
-----
T
F
P
P
S
E
A
V
-
A
R
F
L
K
E
T
P
L
L
T
A
K
P
-
V
I
Y
V
A
N
V
A
E
E
D
L
P
D
G
R
G
-
N
P
Q
V
E
A
V
R
R
K
A
L
E
--
E
G
A
E
V
V
V
--
V
S
-
A
R
L
E
A
E
L
A
E
L
S
G
E
E
A
R
E
L
L
A
A
Y
-
G
L
Q
E
-------
S
G
L
Q
R
---------
L
A
R
A
G
Y
R
A
L
D
L
L
T
F
F
T
A
G
E
K
E
----
V
R
A
W
T
-----
V
-
R
R
G
T
K
A
P
R
A
A
G
E
I
H
S
D
M
E
R
G
F
I
R
A
E
V
I
P
W
D
K
L
V
E
A
G
G
W
A
R
A
K
E
R
G
W
V
R
L
E
G
K
D
Y
E
V
Q
D
G
D
V
I
Y
V
L
F
--
2
PsiBlast_PDB
68.96
53%
34
- C1 -
2DWQ
-
?
A:
[2-367]
---------
L
A
V
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
R
A
N
-
A
-
L
A
A
-----
T
I
D
K
N
V
G
V
V
P
-
L
E
D
E
R
L
Y
A
L
Q
R
T
F
AKG
E
R
V
P
----
P
--
V
V
P
T
H
V
E
F
V
D
I
A
G
L
V
K
G
A
H
K
G
E
--
G
L
G
---
N
Q
F
L
A
H
I
R
-
E
V
A
A
I
A
H
V
L
R
C
F
P
D
P
---------
D
P
L
E
D
A
E
V
V
E
T
E
L
L
L
A
D
L
A
T
L
E
R
R
L
E
R
L
R
K
-
E
A
R
A
-----------------
D
R
E
R
L
P
L
--
L
E
A
--------
A
E
G
L
Y
V
H
-
L
Q
-
E
G
K
P
A
R
-----
T
F
P
P
S
E
A
V
-
A
R
F
L
K
E
T
P
L
L
T
A
K
P
-
V
I
Y
V
A
N
V
A
E
E
D
L
P
D
G
R
G
-
N
P
Q
V
E
A
V
R
R
K
A
L
E
--
E
G
A
E
V
V
V
--
V
S
-
A
R
L
E
A
E
L
A
E
L
S
G
E
E
A
R
E
L
L
A
A
Y
-
G
L
Q
E
-------
S
G
L
Q
R
---------
L
A
R
A
G
Y
R
A
L
D
L
L
T
F
F
T
A
G
E
K
E
----
V
R
A
W
T
-----
V
-
R
R
G
T
K
A
P
R
A
A
G
E
I
H
S
D
M
E
R
G
F
I
R
A
E
V
I
P
W
D
K
L
V
E
A
G
G
W
A
R
A
K
E
R
G
W
V
R
L
E
G
K
D
Y
E
V
Q
D
G
D
V
I
Y
V
L
F
N
-
93
Fugue
67.95
43%
41
- C1 -
5EE0
-
?
A:
[16-387]
PILGRFS
S
H
L
K
I
G
I
V
G
L
P
N
V
G
K
S
T
F
F
N
I
V
T
K
L
S
-
I
-
P
A
E
N
F
P
F
C
T
I
D
P
N
E
A
R
V
Y
-
V
P
D
E
R
F
D
W
L
C
------
Q
L
Y
K
----
P
K
S
E
V
S
A
Y
L
E
I
N
D
I
A
G
L
----------
G
L
G
---
N
A
F
L
S
H
I
R
-
A
V
D
G
I
F
H
V
L
R
A
F
E
D
K
E
V
T
H
I
D
D
S
V
D
P
V
R
D
L
E
T
I
G
E
E
L
R
L
K
D
I
E
F
V
Q
N
K
I
D
D
L
E
K
-
S
M
K
R
S
---------
N
------
D
K
Q
L
K
L
E
--
H
E
L
--------
C
E
K
V
K
A
H
-
L
E
-
D
G
K
D
V
R
-----
F
G
D
W
K
S
A
D
-
I
E
I
L
N
T
F
Q
L
L
T
A
K
P
-
V
V
Y
L
V
N
M
S
E
K
D
Y
Q
R
K
K
--
N
K
F
L
P
K
I
H
A
W
V
Q
E
--
H
G
G
E
T
I
I
--
P
F
S
C
A
F
E
R
L
L
A
D
M
P
P
D
E
A
A
K
Y
C
A
E
N
-
Q
I
A
--------
S
V
I
P
K
---------
I
I
K
T
G
F
A
A
I
H
L
I
Y
F
F
T
A
G
P
D
E
----
V
K
C
W
Q
-----
I
-
R
R
Q
T
K
A
P
Q
A
A
G
T
I
H
T
D
F
E
R
G
F
I
C
A
E
V
M
K
F
D
D
L
K
E
L
G
S
E
S
A
V
K
A
A
G
K
Y
R
Q
E
G
K
T
Y
V
V
Q
D
G
D
I
I
F
F
K
F
N
-
66
HHSearch
63.56
40%
23
- C1 -
1NI3
1
OLA1_SCHPO
A:
[21-388]
---------
L
K
T
G
I
V
G
M
P
N
V
G
K
S
T
F
F
R
A
I
T
K
S
V
-
L
G
N
P
A
N
Y
P
Y
A
T
I
D
P
E
E
A
K
V
A
-
V
P
D
E
R
F
D
W
L
C
------
E
A
Y
K
----
P
K
S
R
V
P
A
F
L
T
V
F
D
I
A
G
L
T
K
G
A
S
T
G
V
--
G
L
G
---
N
A
F
L
S
H
V
R
-
A
V
D
A
I
Y
Q
V
V
R
A
F
D
D
A
E
I
I
H
V
E
G
D
V
D
P
I
R
D
L
S
I
I
V
D
E
L
L
I
K
D
A
E
F
V
E
K
H
L
E
G
L
R
K
-
I
T
S
R
----------
G
ANTLE
M
K
A
K
K
E
E
Q
--
A
I
I
--------
E
K
V
Y
Q
-
Y
-
L
T
E
T
K
Q
P
I
R
-----
K
G
D
W
S
N
R
E
-
V
E
I
I
N
S
L
Y
L
L
T
A
K
P
-
V
I
Y
L
V
N
M
S
E
R
D
F
L
R
-
Q
K
-
N
K
Y
L
P
K
I
K
K
W
I
D
E
NS
P
G
D
T
L
I
P
--
M
S
-
V
A
F
E
E
R
L
T
N
F
T
E
E
E
A
I
E
E
C
K
K
L
-
N
T
K
--------
S
M
L
P
K
---------
I
I
V
T
G
Y
N
A
L
N
L
I
N
Y
F
T
C
G
E
D
E
----
V
R
S
W
T
-----
I
-
R
K
G
T
K
A
P
Q
A
A
G
V
I
H
T
D
F
E
K
A
F
V
V
G
E
I
M
H
Y
Q
D
L
F
D
Y
K
T
E
N
A
C
R
A
A
G
K
Y
L
T
K
G
K
E
Y
V
M
E
S
G
D
I
A
H
W
K
---
7
PsiBlast_PDB
60.98
39%
34
- C1 -
1NI3
1
OLA1_SCHPO
A:
[21-388]
---------
L
K
T
G
I
V
G
M
P
N
V
G
K
S
T
F
F
R
A
I
T
K
S
V
L
G
-
N
P
A
N
Y
P
Y
A
T
I
D
P
E
E
A
K
V
A
-
V
P
D
E
R
F
D
W
L
C
------
E
A
Y
K
----
P
K
S
R
V
P
A
F
L
T
V
F
D
I
A
G
L
T
K
G
A
S
T
G
V
--
G
L
G
---
N
A
F
L
S
H
V
R
-
A
V
D
A
I
Y
Q
V
V
R
A
F
D
D
A
E
I
I
H
V
E
G
D
V
D
P
I
R
D
L
S
I
I
V
D
E
L
L
I
K
D
A
E
F
V
E
K
H
L
E
G
L
R
K
-
I
T
S
R
GANTLE
M
K
A
K
K
------
E
E
Q
A
I
I
E
K
V
Y
Q
Y
--------
L
T
-------
E
-
T
K
Q
P
I
R
-----
K
G
D
W
S
N
R
E
-
V
E
I
I
N
S
L
Y
L
L
T
A
K
P
-
V
I
Y
L
V
N
M
S
E
R
D
F
L
R
-
Q
K
-
N
K
Y
L
P
K
I
K
K
W
I
D
E
--
N
S
P
G
D
T
L
--
I
P
-
M
S
V
A
F
E
------
E
R
L
T
N
F
T
E
E
E
-
A
I
E
E
C
K
K
L
NTK
S
M
L
P
K
---------
I
I
V
T
G
Y
N
A
L
N
L
I
N
Y
F
T
C
G
E
D
E
----
V
R
S
W
T
-----
I
-
R
K
G
T
K
A
P
Q
A
A
G
V
I
H
T
D
F
E
K
A
F
V
V
G
E
I
M
H
Y
Q
D
L
F
D
Y
K
T
E
N
A
C
R
A
A
G
K
Y
L
T
K
G
K
E
Y
V
M
E
S
G
D
I
A
H
W
K
---
91
HHSearch
41.77
25%
-176
- C1 -
2QTF
3
HFLX_SULSO
A:
[179-270]
--------
I
P
S
I
G
I
V
G
Y
T
N
S
G
K
T
S
L
F
N
S
L
T
G
L
-------------
M
S
P
K
R
Y
A
I
P
-
I
N
N
---------------------------
R
K
I
M
L
V
D
T
V
G
F
I
R
G
I
P
--
P
--
Q
I
V
D
A
F
F
V
T
L
S
E
A
K
-
Y
S
D
A
L
I
L
V
I
D
S
T
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
94
Fugue
41.08
21%
40
- C1 -
1WXQ
-
?
A:
[2-395]
----------
E
I
G
V
V
G
K
P
N
V
G
K
S
T
F
F
S
A
A
T
----------------
L
A
N
V
G
V
T
Y
A
I
T
D
H
P
C
K
E
L
G
------
C
S
P
N
----
P
Q
N
-----
Y
E
Y
R
N
G
L
A
L
I
P
V
K
M
------
V
D
---
V
A
F
L
D
D
L
R
M
A
S
A
L
I
H
V
V
D
A
T
G
K
T
D
P
E
G
Q
P
T
D
Y
H
D
P
V
E
D
I
E
F
L
E
R
E
I
D
Y
W
I
Y
G
I
L
S
K
G
W
D
K
F
A
K
-
R
I
K
L
----------
Q
------
K
I
K
L
E
S
A
--
I
A
E
H
L
SGIGVN
E
N
D
V
W
E
A
M
H
K
-
L
N
L
P
E
D
-----
P
T
K
W
S
Q
D
D
-
L
L
A
F
A
S
E
I
R
R
V
N
K
P
M
V
I
A
A
N
K
A
D
A
------
A
S
-
D
E
Q
I
K
R
L
V
R
E
E
E
K
--
R
G
Y
I
V
I
P
--
T
S
-
A
A
A
E
L
T
L
R
K
A
A
K
A
G
F
I
E
Y
I
P
A
L
M
V
I
K
E
-------
K
V
L
D
R
FGSTG
V
Q
E
V
I
N
R
V
V
F
D
L
L
K
L
I
P
V
Y
P
V
H
D
E
Q
FGNV
L
P
H
V
F
-----
L
M
K
K
G
S
T
P
R
D
L
A
F
K
V
H
T
D
L
G
K
G
F
L
Y
A
I
N
-----------------
A
R
T
K
R
R
V
G
E
D
Y
E
L
Q
F
N
D
I
V
K
I
V
S
V
-
74
HHSearch
38.87
45%
-123
- C1 -
1UDX
3
OBG_THET8
A:
[157-251]
--------
I
A
D
V
G
L
V
G
Y
P
N
A
G
K
S
S
L
L
A
A
M
T
R
A
H
-
P
-
K
I
A
P
Y
P
F
T
T
L
S
P
N
L
G
V
V
E
-
V
S
E
E
--------------------------
E
R
F
T
L
A
D
I
P
G
I
I
E
G
A
S
E
G
K
--
G
L
G
---
L
E
F
L
R
H
I
A
-
R
T
R
V
L
L
Y
V
L
D
A
A
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
75
HHSearch
38.41
40%
-136
- C1 -
1LNZ
2
OBG_BACSU
A:
[158-249]
--------
L
A
D
V
G
L
V
G
F
P
S
V
G
K
S
T
L
L
S
V
V
S
S
A
K
-
P
-
K
I
A
D
Y
H
F
T
T
L
V
P
N
L
G
M
V
E
-
T
D
D
G
--------------------------
R
S
F
V
M
A
D
L
P
G
L
I
E
G
A
H
Q
G
V
--
G
L
G
---
H
Q
F
L
R
H
I
E
-
R
T
R
V
I
V
H
V
I
D
M
S
G
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
85
HHSearch
38.01
28%
-105
- C1 -
2DYK
1
?
A:
[2-91]
---------
H
K
V
V
I
V
G
R
P
N
V
G
K
S
S
L
F
N
R
L
L
K
K
R
-
S
-----------
D
L
K
E
G
V
V
E
-
T
D
R
---------------------------
G
R
F
L
L
V
D
T
G
G
L
W
S
G
D
K
W
E
K
--
K
I
Q
---
E
K
V
D
R
A
L
E
-
D
A
E
V
V
L
F
A
V
D
G
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
36.67
35%
-122
- C1 -
1LNZ
2
OBG_BACSU
A:
[162-275]
------------
G
L
V
G
F
P
S
V
G
K
S
T
L
L
S
V
V
S
S
A
K
-
P
-
K
I
A
D
Y
H
F
T
T
L
V
P
N
L
G
M
V
E
-
T
D
D
G
R
--------------------------
S
F
V
M
A
D
L
P
G
L
I
E
G
A
H
Q
G
V
--
G
L
G
---
H
Q
F
L
R
H
I
E
-
R
T
R
V
I
V
H
V
I
------
D
M
S
G
L
E
G
R
-
D
P
Y
D
D
Y
L
T
I
N
Q
E
L
S
E
Y
N
L
R
L
T
E
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69
HHSearch
35.97
18%
-22
- C1 -
4A9A
-
RBG1_YEAST
A:
[65-369]
--------
V
A
S
V
G
F
V
G
F
P
S
V
G
K
S
T
L
L
S
K
L
T
G
T
E
-
S
-
E
A
A
E
Y
E
F
T
T
L
V
T
V
P
G
V
I
R
-
Y
K
G
---------------------------
A
K
I
Q
M
L
D
L
P
G
I
I
D
G
-------
G
R
G
---
K
Q
V
I
A
V
A
R
-
T
C
N
L
L
F
I
I
L
D
V
N
K
P
------------
L
H
H
K
Q
I
I
E
K
E
L
E
G
V
G
I
R
L
N
K
T
P
P
D
I
L
I
K
-
K
K
E
K
----------
G
G
I
S
I
T
-
N
T
V
P
L
T
H
--
L
G
---------
N
D
E
I
R
A
V
-
M
S
-
E
Y
R
I
N
S
A
E
I
A
F
R
C
D
A
T
V
D
D
L
I
D
V
L
E
A
-
S
S
R
R
Y
M
P
-
A
I
Y
V
L
N
K
I
D
S
L
S
I
E
------
E
L
E
L
L
-----
Y
--
R
I
P
N
A
V
P
--
I
S
-
S
G
Q
D
W
------------------------------
N
L
D
E
---------
L
L
Q
V
M
W
D
R
L
N
L
V
R
I
Y
T
K
P
K
G
Q
----
I
P
D
F
T
DPVVL
R
-
S
D
R
C
S
V
K
D
F
C
N
Q
I
H
K
S
L
V
D
D
F
R
N
A
L
V
Y
G
---------
S
-
S
V
K
H
Q
P
--
Q
Y
V
G
L
S
H
I
L
E
D
E
D
V
V
T
I
L
K
K
-
72
HHSearch
34.39
32%
-96
- C1 -
1MKY
2
DER_THEMA
A:
[180-276]
--------
A
I
K
V
A
I
V
G
R
P
N
V
G
K
S
T
L
F
N
A
I
L
N
K
E
-
R
A
L
V
S
P
I
P
------
V
D
D
E
V
F
-
I
D
G
---------------------------
R
K
Y
V
F
V
D
T
A
G
L
--------EK
Y
S
N
---
Y
R
V
V
D
S
I
E
-
K
A
D
V
V
V
I
V
L
D
A
T
Q
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------