@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv1317c: (2016-04-30 )
MHDDFERCYRAIQSKDARFDGWFVVAVLTTGVYCRPSCPVRPPFARNVRFLPTAAAAQGEGFRACKRCRPDASPGSPEWNVRSDVVARAMRLIADGTVDRDGVSGLAAQLGYTIRQLERLLQAVVGAGPLALARAQRMQTARVLIETTNLPFGDVAFAAGFSSIRQFNDTVRLACDGTPTALRARAAARFESATASAGTVSLRLPVRAPFAFEGVFGHLAATAVPGCEEVRDGAYRRTLRLPWGNGIVSLTPAPDHVRCLLVLDDFRDLMTATARCRRLLDLDADPEAIVEALGADPDLRAVVGKAPGQRIPRTVDEAEFAVRAVLAQQVSTKAASTHAGRLVAAYGRPVHDRHGALTHTFPSIEQLAEIDPGHLAVPKARQRTINALVASLADKSLVLDAGCDWQRARGQLLALPGVGPWTAEVIAMRGLGDPDAFPASDLGLRLAAKKLGLPAQRRALTVHSARWRPWRSYATQHLWTTLEHPVNQWPPQEKIA
Atome Classification :
(22 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270....----...280.......290.......300....-...310.......320.......330.......340.......350.......360.......370---.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MH
D
D
F
E
R
C
Y
R
A
I
QSKDARFD
G
W
F
V
V
A
V
LTTG
V
Y
CRPSCPVRPPFARN
V
R
F
L
PTAAAAQG
E
G
F
R
A
C
K
RCRPDASPGSPEWN
V
R
S
D
V
V
A
R
A
M
R
L
I
ADGTVDRD
G
V
S
G
L
A
A
Q
L
G
Y
T
I
R
Q
L
E
R
L
L
Q
A
V
VGA
G
P
L
A
L
A
R
A
Q
R
M
Q
T
A
R
V
L
I
E
TTNLPF
G
D
V
A
F
A
A
G
F
S
S
I
R
Q
FN
D
T
V
R
L
ACDGT
P
T
A
L
R
A
R
A
A
A
R
FESATASA
G
T
V
S
L
R
LPVRAP
F
A
F
E
G
V
F
G
H
L
A
A
TAVP
G
C
E
E
V
RDGA
Y
R
R
T
L
RLPWGN
G
I
V
SLTPAPD
H
V
R
C
L
L
V
L
D
D
F
R
D
L
M
T
A
T
A
R
C
----
R
R
L
LDLDA
D
P
E
A
I
V
E
A
LGADP
D
L
R
A
V
VGKA-PGQRIPR
T
V
D
E
A
E
F
A
V
R
A
V
L
A
Q
Q
V
S
TKAASTHA
G
R
L
V
AAYGRPVHDRHGALTHT
F
P
S
I
E
Q
L
AEIDP---GHLAV
P
K
A
R
Q
R
T
I
N
A
L
V
A
S
LADK
S
L
V
LDAGC
D
W
Q
R
AR
G
Q
L
L
ALPGVGP
W
T
A
E
V
I
A
MRGLGDPDAFP
A
S
D
L
G
L
R
L
A
A
K
KLGLPAQ
R
R
A
L
T
VHSARWR
P
W
R
S
Y
A
T
Q
H
L
W
T
T
L
EH
P
V
NQWPPQEKIA
1
PsiBlast_PDB
88.37
32%
-78
- C2 -
3OGD
2
3MG2_ECOLI
A:
[2-288]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
I
G
S
E
F
Y
T
L
N
W
Q
P
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
C
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
46
PsiBlast_CBE
83.94
32%
-78
- C2 -
1MPG
1
3MG2_ECOLI
B:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
LAKM
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
QAL
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
3
PsiBlast_PDB
83.53
32%
-73
- C2 -
3OH9
2
3MG2_ECOLI
A:
[2-288]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
I
G
S
E
F
Y
T
L
N
W
Q
P
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
C
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
4
PsiBlast_PDB
83.39
32%
-75
- C2 -
1MPG
1
3MG2_ECOLI
A:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
8
PsiBlast_PDB
83.30
32%
-76
- C2 -
3CVT
2
3MG2_ECOLI
A:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
31
PsiBlast_CBE
82.69
32%
-78
- C2 -
3CWS
2
3MG2_ECOLI
C:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
LAKM
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
QAL
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
47
PsiBlast_CBE
82.47
32%
-79
- C2 -
1DIZ
3
3MG2_ECOLI
B:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
LAKM
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
QAL
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
2
PsiBlast_PDB
82.46
32%
-73
- C2 -
3OH6
2
3MG2_ECOLI
A:
[2-288]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
I
G
S
E
F
Y
T
L
N
W
Q
P
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
C
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
12
PsiBlast_PDB
82.39
32%
-78
- C2 -
3CWT
2
3MG2_ECOLI
A:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
9
PsiBlast_PDB
82.32
32%
-77
- C2 -
3CW7
2
3MG2_ECOLI
A:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
10
PsiBlast_PDB
82.18
32%
-77
- C2 -
3CWA
2
3MG2_ECOLI
A:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
25
PsiBlast_CBE
82.14
32%
-78
- C2 -
3CWU
2
3MG2_ECOLI
C:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
LAKM
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
QAL
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
11
PsiBlast_PDB
82.08
32%
-75
- C2 -
3CWS
2
3MG2_ECOLI
A:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
7
PsiBlast_PDB
81.83
32%
-75
- C2 -
3CVS
2
3MG2_ECOLI
A:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
5
PsiBlast_PDB
81.43
32%
-76
- C2 -
1DIZ
3
3MG2_ECOLI
A:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
30
PsiBlast_CBE
81.42
32%
-77
- C2 -
3CWS
2
3MG2_ECOLI
D:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
LAKM
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
QAL
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
6
PsiBlast_PDB
81.39
32%
-77
- C2 -
1PVS
1
3MG2_ECOLI
A:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
35
PsiBlast_CBE
81.10
32%
-75
- C2 -
3CWA
2
3MG2_ECOLI
B:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
LAKM
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
QAL
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
24
PsiBlast_CBE
80.86
32%
-79
- C2 -
3CWU
2
3MG2_ECOLI
D:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
LAKM
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
QAL
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
38
PsiBlast_CBE
80.81
32%
-75
- C2 -
3CW7
2
3MG2_ECOLI
B:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
LAKM
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
QAL
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
14
PsiBlast_PDB
80.51
32%
-74
- C2 -
3D4V
2
3MG2_ECOLI
A:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
L
A
K
M
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
Q
A
L
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---
21
PsiBlast_CBE
79.25
32%
-74
- C2 -
3D4V
2
3MG2_ECOLI
D:
[9-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Y
D
W
S
W
M
L
G
F
L
A
A
R
A
V
S
S
V
E
T
V
A
D
S
Y
Y
A
R
S
L
A
V
G
E
Y
R
G
V
V
--
T
A
I
P
D
I
A
R
H
T
L
H
I
N
L
S
A
G
L
E
P
V
A
A
E
C
LAKM
S
R
L
F
D
L
Q
C
N
P
Q
I
V
N
G
A
L
G
R
-------
L
G
A
A
R
P
G
L
R
L
P
G
C
V
D
A
F
E
Q
G
V
R
A
I
L
G
Q
L
V
S
V
A
M
A
A
K
L
T
A
R
V
A
Q
L
Y
G
E
R
L
D
D
F
P
E
Y
I
--
C
F
P
T
P
Q
R
L
A
A
A
D
P
QAL
K
A
L
G
M
P
L
K
R
A
E
A
L
I
H
L
A
N
A
A
L
E
G
T
L
P
M
T
I
P
G
D
V
E
Q
A
M
K
T
L
Q
T
F
P
G
I
G
R
W
T
A
N
Y
F
A
L
R
G
W
Q
A
K
D
V
F
L
P
D
D
Y
L
I
K
Q
R
F
P
G
M
-
T
P
A
Q
I
R
R
---
Y
A
E
R
W
K
P
W
R
S
Y
A
L
L
H
I
W
Y
T
-----
E
G
W
Q
P
D
E
---