@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv2921c: (2016-05-14 )
MWEGLWIATAVIAALVVIAALTLGLVLYRRRRISLSPRPERGVVDRSGGYTASSGITFSQTPTTQPAERIDTSGLPAVGDDATVPRDAPKRTIADVHLPEFEPEPQAPEVPEADAIAPPEGRLERLRGRLARSQNALGRGLLGLIGGGDLDEDSWQDVEDTLLVADLGPAATASVVSQLRSRLASGNVRTEADARAVLRDVLINELQPGMDRSIRALPHAGHPSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGAADTFRAAAADQLQTWAARVGAAVVRGPEGADPASVAFDAVDKGIAAGADVVLIDTAGRLHTKVGLMDELDKVKRVVTRRASVDEVLLVLDATIGQNGLAQARVFAEVVDISGAVLTKLDGTAKGGIVFRVQQELGVPVKLVGLGEGPDDLAPFEPAAFVDALLG
Atome Classification :
(47 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.-......140..--..--...150---.----.----......160.......170.......180....----.----.---.---190........200.......210---.-.-----....---.-----.220.-----......230.......240.....-..-250.......260.......270.......280--...-.-...290.......300........310.......320.......330....--.--.--.--340.---........350.......360.......370.......380.......390.......400.......410.......420
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MWE
G
L
W
I
A
T
A
V
I
A
A
L
V
V
I
A
A
L
T
L
G
L
V
L
Y
R
R
RRISLSPRPERGVVDRSGGYTASS
G
I
T
FSQTPTTQ
P
A
E
RIDTSGLPAVGDDATVPRDAPK
R
T
I
A
DVHLPEFEPEPQAPEVPEADAIAPPE
G
R
L
E
R
L
R
G
R
L
A
RS-Q
N
A
L
G
R
G
L
L
G
L--IG--GGDLD----E----
D
----
S
W
Q
D
V
E
D
T
L
L
V
ADLGP
A
A
T
A
S
V
V
S
Q
L
R
S
R
L
ASG----N----V---R---T
E
-
A
D
A
R
A
V
L
R
D
V
L
I
N
ELQPGMD----
R
-
S
-----
I
R
AL---P-----HAGH
P
-----
S
V
L
L
V
V
GVNGTGKT
T
T
V
G
K
L
A
R
V
L
-VA-DG
R
R
V
V
L
GAA
D
T
F
R
A
A
A
A
D
Q
L
Q
T
W
A
A
R
V
G
A
A
V
V--RGP-E-GAD
P
A
S
V
A
F
D
A
V
D
K
-
G
IAAGA
D
V
V
L
I
DTAG
R
L
H
TKVG
L
M
D
E
L
D
K
V
K
R
V
V
T
R--R--A--
S
--
V
--
D
---
E
V
L
L
V
L
DATIGQN
G
L
A
Q
A
R
V
F
A
E
V
VDIS
G
A
V
L
TKLDGTAKG
G
I
V
F
R
V
Q
Q
ELGV
P
V
K
L
V
GLGEGPDDLAPF
E
P
A
A
F
V
D
A
L
LG
116
HHSearch
87.22
41%
-112
- C6 -
2OG2
2
CFTSY_ARATH
A:
[59-359]
----------------------------------------------------------------------------------------------------------------------------
K
V
F
S
G
F
S
K
T
-
R
E
N
L
A
V
-
I
D
E
L
--
L
L
F
W
N
L
A
E
T
----
D
----
R
----
V
L
D
E
L
E
E
A
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
D
I
M
S
G
----
K
----
L
---
K
---
S
G
-
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
---------
K
-----
T
E
L
Q
---
L
-----
G
F
R
K
P
-----
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
-
K
N
-
E
G
T
K
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
R
T
G
C
E
I
V
--
V
A
E
-
G
D
K
A
K
A
A
T
V
L
S
K
A
V
K
R
-
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
--
I
VS
G
--
A
--
P
--
N
---
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
S
128
HHSearch
86.91
48%
-108
- C6 -
1VMA
1
?
A:
[13-305]
-----------------------------------------------------------------------------------------------------------------------
M
G
L
F
D
F
L
K
K
G
L
Q
K
T
-
K
E
T
F
F
G
R
V
V
K
L
--
L
K
--
G
K
K
L
D
----
D
----
E
----
T
R
E
E
L
E
E
L
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
E
E
K
D
G
-----------------------
D
A
L
E
S
L
K
E
I
I
L
E
I
L
N
F
D
T
-------
K
-----
L
--
N
---
V
-----
P
P
E
P
P
-----
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
-
V
D
-
E
G
K
S
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
R
V
G
A
T
V
I
--
S
H
S
-
E
-
G
A
D
P
A
A
V
A
F
D
A
V
A
H
-
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
V
V
K
K
KI
P
--
D
--
A
--
P
--
H
---
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
S
21
PsiBlast_CBE
86.64
46%
-109
- C6 -
1VMA
1
?
B:
[14-304]
------------------------------------------------------------------------------------------------------------------------
G
L
F
D
F
L
K
K
G
L
Q
K
T
-
K
E
T
F
F
G
R
V
V
K
L
--
L
K
--
G
K
K
L
D
----
D
----
E
----
T
R
E
E
L
E
E
L
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
E
E
K
----------------------
D
-
G
D
A
L
E
S
L
K
E
I
I
L
E
I
L
N
--
F
D
----
T
-
K
-----
L
N
V
P
---
P
-----
E
P
--
P
-----
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
-
V
D
-
E
G
K
S
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
R
V
G
A
T
V
I
--
S
H
S
-
E
-
G
A
D
P
A
A
V
A
F
D
A
V
A
H
-
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
V
V
K
K
--
K
--
I
PD
A
--
P
--
H
---
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
-
1
PsiBlast_PDB
86.21
46%
-107
- C6 -
1VMA
1
?
A:
[14-304]
------------------------------------------------------------------------------------------------------------------------
G
L
F
D
F
L
K
K
G
L
Q
K
T
-
K
E
T
F
F
G
R
V
V
K
L
--
L
K
--
G
K
K
L
D
----
D
----
E
----
T
R
E
E
L
E
E
L
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
E
E
K
----------------------
D
-
G
D
A
L
E
S
L
K
E
I
I
L
E
I
L
N
--
F
D
----
T
-
K
-----
L
N
V
P
---
P
-----
E
P
--
P
-----
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
-
V
D
-
E
G
K
S
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
R
V
G
A
T
V
I
--
S
H
S
-
E
-
G
A
D
P
A
A
V
A
F
D
A
V
A
H
-
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
V
V
K
K
--
K
--
I
PD
A
--
P
--
H
---
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
-
120
HHSearch
86.02
41%
-107
- C6 -
3B9Q
1
CFTSY_ARATH
A:
[2-302]
----------------------------------------------------------------------------------------------------------------------------
K
V
F
S
G
F
S
K
T
-
R
E
N
L
A
V
-
I
D
E
L
L
L
F
W
--
N
L
A
E
T
----
D
----
R
----
V
L
D
E
L
E
E
A
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
D
I
M
S
G
----
K
----
L
---
K
---
S
G
-
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
--
S
------
K
-----
T
E
L
Q
---
L
-----
G
F
R
K
P
-----
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
-
K
N
-
E
G
T
K
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
R
T
G
C
E
I
V
--
V
A
E
---
K
A
K
A
A
T
V
L
S
K
A
V
K
R
-
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
--
I
VS
G
--
A
--
P
--
N
---
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
S
3
PsiBlast_PDB
85.75
45%
-114
- C6 -
2OG2
2
CFTSY_ARATH
A:
[92-358]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
E
E
A
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
D
I
M
S
G
----
K
----
L
---
K
---
S
G
-
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
K
--------
T
-----
E
L
Q
L
---
G
-----
F
R
-
K
P
-----
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
-
K
N
-
E
G
T
K
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
R
T
G
C
E
I
V
--
V
A
E
G
D
-
K
A
K
A
A
T
V
L
S
K
A
V
K
R
-
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
--
I
--
V
--
S
GA
P
--
N
---
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
-
2
PsiBlast_PDB
85.23
45%
-112
- C6 -
3B9Q
1
CFTSY_ARATH
A:
[35-301]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
E
E
A
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
D
I
M
S
G
----
K
----
L
---
K
---
S
G
-
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
--
S
----
K
-
T
-----
E
L
Q
L
---
G
-----
F
R
-
K
P
-----
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
-
K
N
-
E
G
T
K
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
R
T
G
C
E
I
V
--
V
A
E
---
K
A
K
A
A
T
V
L
S
K
A
V
K
R
-
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
--
I
--
V
--
S
GA
P
--
N
---
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
-
117
HHSearch
84.55
41%
-104
- C6 -
2YHS
5
FTSY_ECOLI
A:
[190-494]
--------------------------------------------------------------------------------------------------------------------
P
T
K
E
G
F
F
A
R
L
K
R
S
L
L
K
T
-
K
E
N
L
G
S
G
F
I
S
L
--
F
R
--
G
K
K
I
D
----
D
----
D
----
L
F
E
E
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
----
L
---
R
---
D
A
-
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
E
------
P
-----
L
N
-----
V
-----
E
G
K
A
P
-----
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
-
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
--
A
Q
H
-
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
-
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
--
L
DV
E
--
A
--
P
--
H
---
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
17
PsiBlast_PDB
83.73
47%
-126
- C6 -
2IYL
3
FTSY_THEAQ
D:
[23-282]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
---
A
S
G
----
R
---------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
-------A
T
-----
L
R
K
L
GFN
P
-----
Q
K
--
P
VEPKG
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
-
L
G
K
K
V
M
F
C
A
G
D
T
------
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
--
Q
G
P
-
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
--
A
DP
E
--
E
--
P
--
K
---
E
V
W
L
V
L
D
A
V
T
G
Q
--
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
-
131
HHSearch
83.53
47%
-113
- C6 -
1RJ9
3
FTSY_THEAQ
A:
[27-303]
---------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
-----
E
----
E
----
V
L
E
E
L
E
M
A
L
L
A
A
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
S
G
R
----------------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
E
R
R
A
T
L
R
-
K
-----
L
G
F
N
---
P
Q
KPKP
V
E
P
K
G
-----
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
-
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
--
Q
G
P
-
E
-
G
T
D
S
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
--
A
DP
E
--
E
--
P
--
K
---
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
15
PsiBlast_PDB
82.81
47%
-114
- C6 -
2J7P
7
FTSY_THEAQ
D:
[22-281]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
---
A
S
G
----
R
---------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
-------------------------------
K
P
VEPKG
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
-
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
--
Q
G
P
-
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
--
A
DP
E
--
E
--
P
--
K
---
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
-
23
PsiBlast_CBE
82.70
47%
-118
- C6 -
2Q9C
5
FTSY_THEAQ
B:
[43-302]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
---
A
S
G
----
R
---------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
----------------------------
K
P
K
P
VEPKG
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
-
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
--
Q
G
P
-
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
--
A
DP
E
--
E
--
P
--
K
---
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
-
25
PsiBlast_CBE
82.69
47%
-116
- C6 -
2Q9A
12
FTSY_THEAQ
B:
[43-302]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
---
A
S
G
----
R
---------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
----------------------------
K
P
K
P
VEPKG
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
-
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
--
Q
G
P
-
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
--
A
DP
E
--
E
--
P
--
K
---
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
-
5
PsiBlast_PDB
82.63
45%
-109
- C6 -
4AK9
-
?
A:
[108-382]
---------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
S
----
E
----
S
----
I
L
D
E
L
E
E
V
L
L
V
S
D
F
G
P
K
T
A
L
K
I
V
D
T
I
R
K
D
I
L
A
G
----
R
----
L
---
K
---
S
G
-
P
Q
I
K
E
A
L
K
K
N
I
F
K
L
L
T
E
R
V
T
----
T
-
T
-----
E
L
Q
L
---
G
-----
N
S
-
R
P
-----
A
V
L
M
I
V
G
V
N
G
G
G
K
T
T
T
L
G
K
L
A
N
R
F
-
K
K
-
E
G
V
K
V
L
M
A
A
G
D
T
--
A
A
A
G
E
Q
L
E
V
W
A
Q
R
T
G
S
E
I
V
M
A-------
P
R
P
A
A
V
L
S
Q
A
V
R
R
-
A
V
E
E
D
F
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
N
L
M
E
E
L
R
G
C
K
R
A
V
S
K
--
A
--
L
--
S
--
S
AP
N
---
E
V
L
L
V
L
D
G
T
T
G
L
N
M
L
A
Q
A
R
E
F
N
Q
V
I
G
V
T
G
F
I
L
T
K
L
D
G
T
A
R
G
G
C
V
V
S
V
V
D
E
L
S
I
P
V
K
F
V
G
V
G
E
G
I
D
D
L
Q
P
F
D
A
Q
S
F
V
D
A
L
F
-
26
PsiBlast_CBE
82.61
47%
-114
- C6 -
2J7P
9
FTSY_THEAQ
E:
[22-281]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
---
A
S
G
----
R
---------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
--------------------------------
P
VEPKG
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
-
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
--
Q
G
P
-
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
--
A
DP
E
--
E
--
P
--
K
---
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
-
4
PsiBlast_PDB
82.51
40%
-101
- C6 -
2YHS
5
FTSY_ECOLI
A:
[188-494]
------------------------------------------------------------------------------------------------------------------
E
K
P
T
K
E
G
F
F
A
R
L
K
R
S
L
L
K
T
-
K
E
N
L
G
S
G
F
I
S
L
--
F
R
--
G
K
K
I
D
----
D
----
D
----
L
F
E
E
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
----
L
---
R
----
D
-
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
----
E
-
P
-----
L
N
V
E
---
G
-----
K
A
--
P
-----
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
-
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
--
A
Q
H
-
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
-
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
--
L
DV
E
--
A
--
P
--
H
---
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
28
PsiBlast_CBE
82.33
47%
-110
- C6 -
2CNW
5
FTSY_THEAQ
E:
[23-282]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
-----
G
----
R
---------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
E
R
----
R
A
T
-----
L
R
K
L
GFN
P
-----
Q
K
P
K
P
VEPKG
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
-
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
--
Q
G
P
-
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
--
A
DP
E
--
E
--
P
--
K
---
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
-
16
PsiBlast_PDB
82.29
47%
-107
- C6 -
2CNW
5
FTSY_THEAQ
D:
[23-282]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
---
A
S
G
----
R
---------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
E
R
----
R
A
T
-----
L
R
K
L
G
F
-------
Q
K
P
K
P
V
E
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
-
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
--
Q
G
P
-
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
--
A
DP
E
--
E
--
P
--
K
---
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
-
18
PsiBlast_PDB
81.88
47%
-111
- C6 -
1RJ9
3
FTSY_THEAQ
A:
[43-302]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
---
A
S
G
----
R
---------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
E
R
----
R
A
T
-----
L
R
K
L
G
F
N
P
-----
Q
K
P
K
P
VEPKG
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
-
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
--
Q
G
P
-
E
-
G
T
D
S
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
--
A
DP
E
--
E
--
P
--
K
---
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
-
27
PsiBlast_CBE
81.51
47%
-111
- C6 -
2CNW
5
FTSY_THEAQ
F:
[23-282]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
---
A
S
G
----
R
---------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
--------------------------------
P
VEPKG
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
-
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
--
Q
G
P
-
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
--
A
DP
E
--
E
--
P
--
K
---
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
-
13
PsiBlast_PDB
81.50
47%
-115
- C6 -
1OKK
8
FTSY_THEAQ
D:
[42-301]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
---
A
S
G
----
R
---------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
--------------------------------
P
VEPKG
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
-
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
--
Q
G
P
-
E
-
G
T
D
P
A
A
L
A
Y
D
A
V
Q
A
-
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
--
A
DP
E
--
E
--
P
--
K
---
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
-
29
PsiBlast_CBE
80.17
42%
-103
- C6 -
4C7O
5
FTSY_ECOLI
D:
[1-274]
-------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
K
I
D
----
D
----
D
----
L
F
E
E
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
----
L
---
R
----
D
-
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
----
E
-
P
-----
L
N
V
E
---
G
-----
K
A
--
P
-----
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
-
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
--
A
Q
H
-
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
-
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
-
K
--
K
--
L
--
D
--
V
--
E
APH
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
-
49
PsiBlast_CBE
79.96
35%
-99
- C6 -
2J7P
11
SRP54_THEAQ
A:
[7-293]
----------------------------------------------------------------------------------------------------------------------------------
A
R
L
-
Q
E
A
I
G
R
----
L
--
R
G
--
R
G
R
I
T
----
E
----
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
---
E
S
-
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
----
G
-
E
-----
A
R
-
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
19
PsiBlast_PDB
79.59
42%
-102
- C6 -
4C7O
4
FTSY_ECOLI
B:
[5-274]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
D
----
D
----
D
----
L
F
E
E
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
----
L
---
R
----
D
-
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
----
E
-
P
-----
L
N
V
E
---
G
-----
K
A
--
P
-----
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
-
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
--
A
Q
H
-
T
-
G
A
D
S
A
S
V
I
F
D
A
I
Q
A
-
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
-
K
--
K
--
L
--
D
--
V
--
E
APH
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
-
53
PsiBlast_CBE
79.33
35%
-99
- C6 -
1OKK
17
SRP54_THEAQ
A:
[7-293]
----------------------------------------------------------------------------------------------------------------------------------
A
R
L
-
Q
E
A
I
G
R
----
L
--
R
G
--
R
G
R
I
T
----
E
----
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
---
E
S
-
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
----
G
-
E
-----
A
R
-
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
48
PsiBlast_CBE
79.31
35%
-104
- C6 -
2J7P
8
SRP54_THEAQ
B:
[7-293]
----------------------------------------------------------------------------------------------------------------------------------
A
R
L
-
Q
E
A
I
G
R
----
L
--
R
G
--
R
G
R
I
T
----
E
----
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
---
E
S
-
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
----
G
-
E
-----
A
R
-
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
46
PsiBlast_CBE
77.94
35%
-101
- C6 -
3NG1
7
SRP54_THEAQ
B:
[7-293]
----------------------------------------------------------------------------------------------------------------------------------
A
R
L
-
Q
E
A
I
G
R
----
L
--
R
G
--
R
G
R
I
T
----
E
----
E
DLKA
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
---
E
S
-
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
----
G
-
E
-----
A
R
-
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
47
PsiBlast_CBE
77.90
35%
-101
- C6 -
3NG1
6
SRP54_THEAQ
A:
[7-293]
----------------------------------------------------------------------------------------------------------------------------------
A
R
L
-
Q
E
A
I
G
R
----
L
--
R
G
--
R
G
R
I
T
----
E
----
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
---
E
S
-
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
----
G
-
E
-----
A
R
-
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
67
PsiBlast_CBE
77.56
35%
-97
- C6 -
1O87
7
SRP54_THEAQ
B:
[7-293]
----------------------------------------------------------------------------------------------------------------------------------
A
R
L
-
Q
E
A
I
G
R
----
L
--
R
G
--
R
G
R
I
T
----
E
----
E
DLKA
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
---
E
S
-
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
----
G
-
E
-----
A
R
-
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
125
HHSearch
77.17
33%
-105
- C6 -
3DM5
10
SRP54_PYRFU
A:
[3-314]
--------------------------------------------------------------------------------------------------------------------------
L
D
N
L
G
K
A
L
A
N
T
--------
L
K
K
I
--
A
R
--
A
S
S
V
D
----
E
A
L
I
K
E
----
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
KPPA
G
----
I
---
S
---
K
K
-
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
A
K
------
P
-----
I
------
E
-----
I
K
E
K
P
-----
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
-
Q
K
-
R
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
--
G
N
P
-
Q
-
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
-
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
Q
I
S
N
V
I
----------
H
--
P
--
H
---
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
68
PsiBlast_CBE
77.09
35%
-98
- C6 -
1O87
7
SRP54_THEAQ
A:
[7-293]
----------------------------------------------------------------------------------------------------------------------------------
A
R
L
-
Q
E
A
I
G
R
----
L
--
R
G
--
R
G
R
I
T
----
E
----
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
---
E
S
-
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
----
G
-
E
-----
A
R
-
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
38
PsiBlast_CBE
77.08
35%
-98
- C6 -
2NG1
4
SRP54_THEAQ
A:
[6-292]
----------------------------------------------------------------------------------------------------------------------------------
A
R
L
-
Q
E
A
I
G
R
----
L
--
R
G
--
R
G
R
I
T
----
E
----
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
---
E
S
-
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
----
G
-
E
-----
A
R
-
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
31
PsiBlast_CBE
76.97
38%
-106
- C6 -
3DMD
4
?
B:
[39-324]
-----------------------------------------------------------------------------------------------------------------------------------------
L
D
R
I
L
T
V
E
--
I
K
--
E
K
D
V
D
----
K
---------
A
L
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
----
K
----
V
---
R
---
I
G
-
T
D
K
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
----
T
-
S
RRID
L
I
E
E
I
---
R
-----
K
A
E
K
P
-----
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
-
K
N
-
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
V
I
--
K
H
S
-
Y
-
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
-
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
--------
T
--
K
--
P
--
N
---
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
30
PsiBlast_CBE
76.67
38%
-107
- C6 -
3DMD
8
?
C:
[39-324]
-----------------------------------------------------------------------------------------------------------------------------------------
L
D
R
I
L
T
V
E
--
I
K
--
E
K
D
V
D
----
K
---------
A
L
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
----
K
----
V
---
R
---
I
G
-
T
D
K
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
----
T
-
S
RRID
L
I
E
E
I
---
R
-----
K
A
E
K
P
-----
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
-
K
N
-
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
V
I
--
K
H
S
-
Y
-
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
-
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
--------
T
--
K
--
P
--
N
---
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
59
PsiBlast_CBE
76.65
35%
-96
- C6 -
1JPN
4
SRP54_THEAQ
A:
[7-293]
----------------------------------------------------------------------------------------------------------------------------------
A
R
L
-
Q
E
A
I
G
R
----
L
--
R
G
--
R
G
R
I
T
----
E
----
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
---
E
S
-
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
----
G
-
E
-----
A
R
-
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
60
PsiBlast_CBE
76.51
35%
-98
- C6 -
1JPJ
1
SRP54_THEAQ
A:
[7-293]
----------------------------------------------------------------------------------------------------------------------------------
A
R
L
-
Q
E
A
I
G
R
----
L
--
R
G
--
R
G
R
I
T
----
E
----
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
---
E
S
-
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
----
G
-
E
-----
A
R
-
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
54
PsiBlast_CBE
76.46
35%
-96
- C6 -
1NG1
13
SRP54_THEAQ
A:
[7-293]
----------------------------------------------------------------------------------------------------------------------------------
A
R
L
-
Q
E
A
I
G
R
----
L
--
R
G
--
R
G
R
I
T
----
E
----
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
---
E
S
-
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
----
G
-
E
-----
A
R
-
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
39
PsiBlast_CBE
76.07
35%
-100
- C6 -
1RJ9
3
SRP54_THEAQ
B:
[14-293]
------------------------------------------------------------------------------------------------------------------------------------------
G
R
----
L
--
R
G
--
R
G
R
I
T
----
E
----
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
---
E
S
-
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
----
G
-
E
-----
A
R
-
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
55
PsiBlast_CBE
75.98
35%
-104
- C6 -
1LS1
4
SRP54_THEAQ
A:
[7-293]
----------------------------------------------------------------------------------------------------------------------------------
A
R
L
-
Q
E
A
I
G
R
----
L
--
R
G
--
R
G
R
I
T
----
E
----
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
---
E
S
-
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
----
G
-
E
-----
A
R
-
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
------
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
124
HHSearch
75.88
39%
-101
* C6 *
3E70
3
?
C:
[52-324]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
V
----
D
----
K
----
A
L
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
----
K
----
V
RIG-----
G
-
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
R
----
I
-
D
L----
I
E
E
I
---
R
-----
K
A
E
K
P
-----
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
-
K
N
-
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
V
I
--
K
H
S
-
Y
-
G
A
D
P
A
A
V
A
Y
D
A
I
Q
H
-
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
T
----------
K
--
P
--
N
---
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
58
PsiBlast_CBE
75.85
35%
-95
- C6 -
1JPN
4
SRP54_THEAQ
B:
[7-293]
----------------------------------------------------------------------------------------------------------------------------------
A
R
L
-
Q
E
A
I
G
R
----
L
--
R
G
--
R
G
R
I
T
----
E
----
E
DLKA
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
---
E
S
-
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
----
G
-
E
-----
A
R
-
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
R
R
R
V
E
E
K
-
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
44
PsiBlast_CBE
75.39
32%
-92
- C6 -
4C7O
5
SRP54_ECOLI
C:
[2-296]
--------------------------------------------------------------------------------------------------------------------------
F
D
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
G
R
L
T
--------
E
D
N
V
----
K
----
D
----
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
----
E
----
V
---
N
---
K
S
-
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
----
E
-
E
-----
N
Q
T
L
---
N
-----
L
A
A
Q
P
P----
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
-
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
--
P
S
D
-
V
-
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
-
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
--------
H
--
A
--
S
--
I
--
N
PV-
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
45
PsiBlast_CBE
75.24
32%
-93
- C6 -
4C7O
4
SRP54_ECOLI
A:
[4-296]
----------------------------------------------------------------------------------------------------------------------------
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
G
R
L
T
--------
E
D
N
V
----
K
----
D
----
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
----
E
----
V
---
N
---
K
S
-
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
----
E
-
E
-----
N
Q
T
L
---
N
-----
L
A
A
Q
P
P----
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
-
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
--
P
S
D
-
V
-
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
-
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
--------
H
--
A
--
S
--
I
--
N
PV-
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
127
HHSearch
74.85
36%
-106
- C6 -
1LS1
4
SRP54_THEAQ
A:
[1-293]
-------------------------------------------------------------------------------------------------------------------------
M
F
Q
Q
L
S
A
R
L
Q
E
A
-
I
G
R
L
---------
R
G
--
R
G
R
I
T
E
E
D
L
K
----
A
----
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
----
V
---
L
ESL
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
R
---------------
L
---
P
-----
V
L
K
D
R
-----
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
--
E
V
M
-
D
-
G
E
S
P
E
S
I
-
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
----------
G
--
P
--
D
---
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
------
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
34
PsiBlast_CBE
73.98
32%
-101
- C6 -
3DM5
10
SRP54_PYRFU
A:
[33-314]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
----
K
----
P
---
P
---
A
G
-
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
----
T
-
E
-----
A
K
P
I
---
E
-----
I
K
E
K
P
-----
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
-
Q
K
-
R
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
--
G
N
P
-
Q
-
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
-
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
Q
I
S
N
V
I
----------
H
--
P
--
H
---
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
118
HHSearch
73.57
31%
-94
- C6 -
4C7O
4
SRP54_ECOLI
A:
[4-296]
----------------------------------------------------------------------------------------------------------------------------
N
L
T
D
R
L
S
R
T
-
L
R
N
I
S
G
R
-
G
-
R
--
L
T
---
E
D
N
V
----
K
----
D
----
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
----
E
VNKS
L
---
T
---
P
G
-
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
Q
-------------
T
L
N
---
L
-----
A
A
Q
P
P
-----
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
-
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
--
P
S
D
-
V
-
G
Q
K
P
V
D
I
V
N
A
A
L
K
E
-
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
S
I
----------
N
--
P
--
V
---
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
33
PsiBlast_CBE
72.12
32%
-101
- C6 -
3DM5
9
SRP54_PYRFU
B:
[33-315]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
----
K
----
P
---
P
---
A
G
-
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
----
T
-
E
-----
A
K
P
I
---
E
-----
I
K
E
K
P
-----
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
-
Q
K
-
R
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
--
G
N
P
-
Q
-
E
K
D
A
I
K
L
A
K
E
G
V
D
Y
-
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
-
M
K
Q
I
S
N
V
I
----------
H
--
P
--
H
---
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G