@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3439c: (2016-05-20 )
MADRLNVAERLAEGRPAAEHTQSYVRACHLVGYQHPDLTAYPAQIHDWYGSEDGLDLHALDADCAQLRAAASVLMEALRMERSQVAVLAAAWTGSGADAAVHFVQRHCETGNSVVTEVRAAAQRCESLRDNLWQLVDSKVATAIAIDERALAQRPAWLAAAEALTTEGADRPTAVEVVRQQIQPYVDDDVRNDWLTTMRSTTAGVAASYDAVTDQLASAPRAHFEIPDDLGPGRQPSPASVPAQPSATAAITPAAALPPPDPVPAVTSRPVTPSDFGSAPGDGSATPAGVGSAGGFGDAGGTGGLGGFAGLAGLANRIVDAVDSLLGSVAEQLGDPLAADNPPGAVDPFAEDAADNADDGDDAHPEEADEAAEPKEATEPDEADEVDDADESVPAERAQDVAEEATLPPVAEPPPPAAPPVAEPPPPVAAPAPPGAPEPANGPSPEALSEGATPCEIAADELPQAGP
Atome Classification :
(20 SA)
---------.........10........20........30-----........40....-.-...50........60....-....70..-------.....-.80........90........100.......110.......120.......130.......140.......150..---...-..160.-------......170.......180.......190.......200...-....210.......220.......230.......240.......250.......260.....--..270.......280.......290........300.......310.......320.......330.......340--.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.....-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------MA
D
R
L
N
V
A
E
R
L
AEGRP
A
A
E
H
T
Q
S
Y
V
R
A
C
H
LV-----GYQHPDLTAYP
A
Q
I
-
H
-DWYGSEDG
L
D
L
HAL
D
A
D
C
A
-
Q
L
R
A
A
A
S
V
-------
L
M
E
A
L
-
R
M
E
R
S
Q
V
A
V
L
A
A
A
WTGS
G
A
D
A
A
V
H
F
V
Q
R
HCETG
N
S
V
V
T
E
V
R
A
A
A
Q
R
C
E
S
L
R
D
N
L
W
Q
L
V
D
S
KV
A
T
A
I
A
I
D
E
R
A
L
AQR---
P
A
W
-
L
A
A
A
E
A
-------
L
TTEGADR
P
T
A
V
E
V
V
R
Q
Q
I
Q
P
YVD
D
D
V
R
N
D
W
L
T
T
M
RSTTAGV-AA
S
Y
D
A
V
T
D
Q
L
ASAPRAHFEIPDDLGPGRQPSPASVPAQPSATAAITPAAALPPPDPVPAVT--SRPV
T
P
S
DFGSAPGDGSATPAGV-GSAGGFGDAGGTGGL
G
G
F
A
G
L
A
G
L
A
N
R
I
V
D
A
V
D
S
L
L
G
S
V
A
E
QLGDPLAADNP--PGAVDPFAEDAADNADDGDDAH
P
E
E
A
DEAAEPKEATEPDEADEVDDADESV
P
A
E
R
A
Q
D
V
A
E
EATLPPVAEPPPPAAPPVAEPPPPVAAPAPPGAPEPANGP
S
P
E
A
L
SEGATP
C
E
I
A
A
D
ELPQAGP-
89
Fugue
69.73
14%
17
- C2 -
4HE8
1
NQO13_THET8
G:
[1-467]
MVVLAVLLP
V
V
F
G
A
L
L
L
L
G
L
P
R
A
L
G
V
L
G
A
G
L
S
F
L
L
N
L
Y
L
F
LTHPG
G
V
A
H
A
F
Q
A
P
L
L
P
G
A
-
G
V
Y
W
A
F
G
L
D
G
L
S
A
L
F
F
L
T
I
A
L
-
T
V
F
L
G
A
L
V
ARVEGRF
L
G
L
A
L
-
L
M
E
G
L
L
L
G
L
F
A
A
----
R
D
L
L
V
F
Y
V
F
F
E
A
A
L
I
P
A
L
L
M
L
Y
L
Y
G
G
E
G
R
T
R
A
L
Y
T
F
V
L
F
T
L
V
G
S
L
P
M
L
A
A
V
L
G
A
R
L
L
S
G
S
---
P
T
F
L
L
E
D
L
L
A
-------
H
P
L
Q
E
E
A
A
F
W
V
F
L
G
F
A
L
A
F
A
I
K
T
P
L
F
P
L
H
A
W
L
P
P
F
H
Q
E
N
H
P
S
G
L
A
D
A
L
G
T
L
Y
K
V
G
V
F
A
F
F
R
F
---------------
A
I
P
L
A
P
E
G
F
A
Q
A
Q
G
L
L
L
F
L
A
A
L
S
A
L
Y
G
A
--
W
V
A
F
A
A
K
D
F
K
T
L
L
A
Y
A
G
L
S
H
M
G
V
-
A
A
L
G
V
F
--
S
G
T
P
E
G
A
M
G
G
L
Y
L
L
A
A
S
G
V
Y
T
G
G
L
F
L
L
A
G
R
L
Y
E
R
T
G
T
L
E
I
G
R
Y
R
GL
A
Q
S
A
P
G
L
A
A
-
L
A
L
I
L
F
L
A
M
V
G
L
P
G
L
S
G
F
P
G
E
F
L
T
L
L
G
A
Y
K
A
S
P
W
L
A
A
L
A
F
L
S
V
I
A
S
A
A
Y
A
L
T
A
F
Q
K
T
F
W
E
E
G
G
S
G
V
K
D
L
A
G
A
E
W
G
F
A
L
L
S
V
L
A
L
L
L
M
G
V
F
P
G
Y
F
A
-----
R
G
L
H
P
L
A
E
A
F
A
K
L
L
G
G
85
Fugue
64.82
29%
7
- C2 -
1O9G
-
AVRA_STRVR
A:
[2-250]
----------------------------------------------------
S
A
Y
R
H
A
V
E
R
M
D
S
S
D
L
A
C
G
V
V
L
H
S
A
P
G
Y
P
A
F
P
V
R
L
A
T
E
I
-------
F
Q
R
A
L
A
R
L
P
G
D
G
P
V
T
L
W
D
P
C
C
G
S
G
Y
L
L
T
V
L
G
L
L
H
R
R
S
L
R
Q
V
I
A
S
D
V
D
P
A
P
L
--
E
L
A
A
K
N
L
A
-
L
L
S
P
A
G
L
T
A
R
E
L
E
R
R
E
Q
S
E
R
FGK
P
S
Y
-
L
E
A
A
Q
A
A
R
R
L
R
E
R
L
T
A
E
G
G
A
L
P
C
A
I
R
T
----------
A
D
V
F
D
--
P
R
A
L
S
A
V
L
A
G
---
S
A
P
D
V
V
L
T
D
L
P
Y
G
E
R
T
H
W
E
-------------
G
Q
V
P
G
Q
P
V
A
G
L
L
R
S
L
A
S
A
L
P
A
H
-
A
V
I
A
V
T
D
R
S
R
K
I
P
V
A
P
V
K
A
L
E
R
L
K
I
G
T
R
S
A
V
M
V
R
A
A
D
V
L
E
A
G
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
86
Fugue
51.53
17%
-34
- C3 -
1WA8
-
B:
[601-695]
-----------------------------------------------------------------
M
T
E
Q
Q
W
N
F
A
G
I
E
A
A
A
S
-
A
I
Q
G
N
V
T
S
-------
I
H
S
L
L
-
D
E
G
K
Q
S
L
T
K
L
A
A
A
W
G
G
S
G
S
E
A
Y
Q
G
V
Q
Q
K
W
D
A
T
A
T
E
L
N
N
A
L
Q
N
L
A
R
T
I
S
E
A
G
Q
A
M
-
A
S
T
E
G
N
V
T
G
M
F
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72
HHSearch
50.00
18%
-43
- C3 -
3FAV
3
ESXB_MYCTU
A:
[12-83]
---------------------------------------------------------------------------
L
A
Q
E
A
G
-
N
F
E
R
I
S
G
D
-------
L
K
T
Q
I
-
D
Q
V
E
S
T
A
G
S
L
Q
G
Q
W
R
G
A
A
G
T
A
A
Q
A
A
V
V
R
F
Q
E
A
A
N
K
Q
K
Q
E
L
D
E
I
S
T
N
I
R
Q
A
G
V
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
49.99
44%
69
- C4 -
2PVV
-
FOLH1_HUMAN
A:
[102-132]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
E
P
P
P
P
G
Y
E
N
V
S
D
I
V
P
P
F
S
A
F
S
P
Q
G
M
P
E
------------------------------
32
PsiBlast_CBE
49.85
44%
69
- C4 -
4JYW
1
FOLH1_HUMAN
A:
[102-132]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
E
P
P
P
P
G
Y
E
N
V
S
D
I
V
P
P
F
S
A
F
S
P
Q
G
M
P
E
------------------------------
67
HHSearch
49.53
18%
-54
- C3 -
3FAV
4
ESXA_MYCTU
B:
[9-80]
--------------------------------------------------------------------------
G
I
E
A
A
A
S
-
A
I
Q
G
N
V
T
S
-------
I
H
S
L
L
-
D
E
G
K
Q
S
L
T
K
L
A
A
A
W
G
G
S
G
S
E
A
Y
Q
G
V
Q
Q
K
W
D
A
T
A
T
E
L
N
N
A
L
Q
N
L
A
R
T
I
S
E
A
G
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
49.34
44%
69
- C4 -
3BHX
-
FOLH1_HUMAN
A:
[102-132]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
E
P
P
P
P
G
Y
E
N
V
S
D
I
V
P
P
F
S
A
F
S
P
Q
G
M
P
E
------------------------------
8
PsiBlast_PDB
49.34
44%
76
- C4 -
4NGP
-
FOLH1_HUMAN
A:
[132-161]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
E
P
P
P
P
G
Y
E
N
V
S
D
I
V
P
P
F
S
A
F
S
P
Q
G
M
P
E
------------------------------
13
PsiBlast_PDB
49.32
44%
79
- C4 -
4X3R
-
FOLH1_HUMAN
A:
[132-166]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
E
P
P
P
P
G
Y
E
N
V
S
D
I
V
P
P
F
S
A
F
S
P
Q
G
M
P
E
------------------------------
66
HHSearch
49.17
15%
-36
- C3 -
4LWS
10
?
B:
[12-89]
---------------------------------------------------------------------
R
A
N
F
G
G
L
S
E
G
E
A
-
Q
F
S
M
T
A
R
A
-------
L
L
D
E
L
-
T
D
L
E
G
K
L
R
A
K
L
D
R
W
D
G
D
A
Q
A
A
Y
W
N
Y
Q
K
E
W
D
A
A
A
K
D
M
Q
N
V
V
A
Q
L
G
V
A
I
R
E
A
H
D
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
49.15
44%
86
- C4 -
4LQG
1
FOLH1_HUMAN
A:
[102-134]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
E
P
P
P
P
G
Y
E
N
V
S
D
I
V
P
P
F
S
A
F
S
P
Q
G
M
P
E
------------------------------
12
PsiBlast_PDB
48.76
44%
87
- C4 -
4NGT
-
FOLH1_HUMAN
A:
[132-164]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
E
P
P
P
P
G
Y
E
N
V
S
D
I
V
P
P
F
S
A
F
S
P
Q
G
M
P
E
------------------------------
4
PsiBlast_PDB
48.66
44%
69
- C4 -
4MCR
-
FOLH1_HUMAN
A:
[150-180]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
E
P
P
P
P
G
Y
E
N
V
S
D
I
V
P
P
F
S
A
F
S
P
Q
G
M
P
E
------------------------------
20
PsiBlast_PDB
48.40
44%
69
- C4 -
3BI1
-
FOLH1_HUMAN
A:
[102-132]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
E
P
P
P
P
G
Y
E
N
V
S
D
I
V
P
P
F
S
A
F
S
P
Q
G
M
P
E
------------------------------
19
PsiBlast_PDB
48.30
44%
76
- C4 -
3BI0
-
FOLH1_HUMAN
A:
[102-132]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
E
P
P
P
P
G
Y
E
N
V
S
D
I
V
P
P
F
S
A
F
S
P
Q
G
M
P
E
------------------------------
74
HHSearch
48.09
15%
-46
- C3 -
4LWS
5
?
A:
[38-115]
----------------------------------------------------------------------
V
D
R
A
A
M
A
Q
A
A
Q
-
D
I
E
Q
S
A
N
A
-------
I
R
G
M
Q
-
N
Q
L
A
S
A
K
D
Q
L
R
S
H
W
E
G
D
A
S
M
A
F
E
A
V
F
N
R
F
N
E
D
F
S
R
V
L
K
A
L
D
G
M
H
E
S
L
V
Q
T
R
I
T
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
76
HHSearch
47.92
16%
-58
- C3 -
3GWK
1
?
C:
[7-85]
---------------------------------------------------------------------
K
L
T
P
E
E
L
R
S
S
A
Q
-
K
Y
T
A
G
S
Q
Q
-------
V
T
E
V
L
-
N
L
L
T
Q
E
Q
A
V
I
D
E
N
W
D
G
S
T
F
D
S
F
E
A
Q
F
N
E
L
S
P
K
I
T
E
F
A
Q
L
L
E
D
I
N
Q
Q
L
L
K
V
A
D
I
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
47.85
44%
116
- C4 -
4OC2
1
FOLH1_HUMAN
A:
[102-132]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
E
P
P
P
P
G
Y
E
N
V
S
D
I
V
P
P
F
S
A
F
S
P
Q
G
M
P
E
------------------------------
11
PsiBlast_PDB
47.75
44%
116
- C4 -
4NGS
-
FOLH1_HUMAN
A:
[132-160]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
E
P
P
P
P
G
Y
E
N
V
S
D
I
V
P
P
F
S
A
F
S
P
Q
G
M
P
E
------------------------------