@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3599c: (2016-05-21 )
MPASSLGTGSPAADRLDATHERRREVI
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.......----..10.-....--------..---.20.-..-----...---------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPASSLG----TGSPA-ADRL--------DA---THER-RR-----EVI---------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
74.85
28%
-67
- C8 -
2H1Z
-
?
A:
[1-39]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
C
V
P
----
V
D
Q
P
C
-
S
L
N
T
Q
P
C
C
D---
D
A
---
T
C
T
Q
-
E
R
N
ENG
H
T
V
Y
Y
C
R
A-----------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
71.47
33%
-11
- C10 -
1TRE
-
TPIS_ECOLI
A:
[3-257]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
R
H
P
L
V
M
G
NWKLNGS
R
H
M
V
H
E
L
V
S
N
L
R
K
E
L
A
GVAG
C
A
V
A
I
A
P
PEMY
I
D
M
A
K
R
E
A
EGSH
I
M
L
G
A
QNVNLNLSGAFTGETS
A
A
M
L
K
D
I
GAQ
Y
I
I
I
GH
S
E
R
R
T
YHKES
D
E
L
I
A
K
K
F
A
V
L
K
E
Q
GLTPV
L
C
I
G
E
T
E
A
E
N
E
A
GK
T
E
E
V
C
A
R
Q
I
D
AVLKTQGAAAFEG
A
V
I
A
Y
E
P
V
W
A
I
G
----
T
G
K
S
A
T
P
A
Q
A
--------
Q
A
---
V
H
K
F
-
I
R
-----
D
H
I
A
K
V
D
A
N
I
A
E
Q
V
I
I
Q
Y
GGSVNASN
A
A
E
L
F
A
QPDIDGALVG
G
A
S
L
K
A
D
A
F
A
V
I
V
K
A
A
E
A
A
K
QA--------------------------------------------------------------------------------------------------------
19
Fugue
66.37
37%
-8
- C10 -
4IMP
1
?
A:
[31-550]
SD
P
A
A
G
W
F
W
Q
A
V
A
R
QD
L
K
S
V
S
D
A
L
DLDADAP
L
S
A
T
L
P
A
L
S
V
W
H
R
Q
E
R
E
R
V
L
A
D
G
W
R
Y
R
V
D
W
V
R
V
A
P
Q
P
VRR
T
R
E
T
W
L
L
V
V
P
PGGIE
E
A
L
V
E
R
L
T
D
A
L
N
T
R
G
I
S
T
L
R
L
D
V
P
P
AAT
S
G
E
L
A
T
E
L
R
A
A
A
D
G
DPVK
A
I
L
S
LTALDERPHPECKDVP
S
G
I
A
L
L
L
N
L
V
K
A
L
G
E
A
DLR
I
P
L
W
T
I
T
R
GAVKAGPADRLLR
P
M
Q
A
Q
A
W
G
L
G
R
V
A
A
L
E
HPERWG
G
L
I
D
L
P
DSLDGD
V
L
T
R
L
G
E
A
L
T
NGLAED
Q
L
A
I
R
QS
G
V
L
A
R
R
L
V
P
A
P
ANQPAGRK
W
R
P
R
G
S
A
L
I
T
GGLG
A
V
G
A
Q
V
A
R
W
L
A
E
I
GAE
R
I
V
L
T
S
RRGNQAAG
A
A
E
L
E
A
E
L
R
A
L
G
A
Q
V
S
I
V
ACDVTD
R
A
E
M
S
A
L
L
A
E
F
DVT
A
V
F
H
A
A
G
V
G
R
L
L
P
LAETD
Q
N
G
L
A
E
I
C
A
A
K
V
R
G
A
Q
V
L
D
E
L
C
DSTDLDAF
V
L
F
S
S
GAGVWGGGGQ
G
A
Y
G
A
A
N
A
F
L
D
T
L
A
E
Q
R
R
A
R
G
L
P
A
T
S
I
S
W
G
S
W
A
G
G
G
M
-
A
D
G
A
--------
A
G
---
E
H
L
R
-
R
R
-----
G
I
R
P
M
P
A
A
S
A
I
L
A
L
Q
E
V
L
D
Q
DET
C
V
S
I
A
DVD
W
D
R
F
V
P
T
F
A
A
TRATRLFDEV
P
A
A
R
K
AM--------------------------------------------------------------------------------------------------------------
12
HHSearch
65.88
25%
-9
- C10 -
2J27
1
TPIS_TRYBB
A:
[168-192]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
W
A
I
G
----
T
G
K
V
A
T
P
Q
Q
A
--------
Q
E
---
A
H
A
L
-
I
R
-----
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
60.57
25%
-41
- C10 -
1IF2
1
TPIS_LEIME
A:
[3-251]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AK
P
Q
P
I
A
A
A
N
WKCNGT
T
A
S
I
E
K
L
V
Q
V
F
N
E
HTIS
H
D
V
Q
C
V
V
A
P
T
FVH
I
P
L
V
Q
A
K
LRNPK
Y
V
I
S
A
QNAIAKSGAFTGEVS
M
P
I
L
K
D
I
GVH
W
V
I
L
GH
S
E
R
R
T
YYGET
D
E
I
V
A
Q
K
V
S
E
A
C
K
Q
GFMVI
A
C
I
G
E
T
L
Q
Q
R
E
A
NQ
T
A
K
V
V
L
S
Q
T
S
A
I
A
A
K
LTKDAWNQ
V
V
L
A
Y
E
P
V
W
A
I
G
----
T
G
K
V
A
T
P
E
Q
A
--------
Q
E
---
V
H
L
L
-
L
R
-----
K
W
V
S
E
NIG
T
D
V
A
A
K
L
R
I
L
Y
G
G
SVNAAN
A
A
T
L
Y
A
KPDIN
G
F
L
V
G
G
A
S
L
K
PE
F
R
D
I
I
D
A
T
R-------------------------------------------------------------------------------------------------------------
22
Fugue
57.50
30%
-7
- C10 -
2YKA
-
B:
[1-23]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
L
G
S
-
S
----
C
K
T
S
W
-
A
D
R
V
--------
R
E
---
A
A
A
Q
-
R
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
51.81
50%
-127
- C2 -
4PK9
-
PAT17_SOLCD
A:
[256-265]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
L
G
----
T
G
T
T
S
-
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
50.77
25%
4
* C10 *
4NY2
4
?
A:
[5-408]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PK
G
T
I
Y
L
T
F
D
DGPV
N
A
S
V
E
V
I
K
V
L
N
Q
G
G
V
K
A
T
F
YFNAWHLDGIGDENEDR
A
L
E
A
L
K
L
A
L
D
S
G
H
I
V
G
N
HSYDHMIHNCVEEFGPT
S
G
A
D
C
N
A
T
GNHQIHSYQD
P
V
R
D
A
A
S
F
E
Q
N
L
I
T
L
E
K
Y
L
PTIRSYPNYKGYE
L
A
R
L
P
YTNGWRVTKH
F
Q
A
D
GLCATSDNLKPWEPG
Y
V
C
D
PANPS
N
S
V
K
A
S
I
Q
V
Q
N
I
L
A
N
Q
G
Y
Q
T
H
G
W
DVDWAPENWGIP
M
P
A
N
S
L
T
----
E
A
V
P
F
-
L
A
Y
V
--------
D
K
---
A
L
N
S
-
C
S
-----
P
T
T
IEPINSKTQEFPCGTPLHAD
K
V
I
V
L
T
H
DFLFEDGKRGMGATQN
L
P
K
L
A
E
F
I
R
I
A
K
E
A
G
Y
V
F
D
T
MDNYTPRWSVG
K
T
Y
Q
AG
E
Y
V
L
Y
QG
V
V
Y
K
A
V
I
S
H
T
A
Q
QDWAPSSTSSLWTNADPATNWTLNVSYEQG
D
I
V
N
Y
KG
K
R
Y
L
V
S
V
P
H
V
S
Q
QDWTPDTQNTL
F
T
A
L
E
L
11
HHSearch
50.00
44%
-82
- C6 -
4H3K
-
SSU72_HUMAN
B:
[53-61]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
S
F
G
----
T
G
T
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
48.93
50%
-72
- C3 -
3P9Y
-
?
A:
[37-44]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
S
Y
G
----
T
G
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
48.58
25%
16
- C9 -
3DSM
1
?
A:
[1-327]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A
S
G
L
F
I
T
N
EGNFQYSN
A
T
L
S
Y
Y
D
PATC
E
V
E
N
E
V
F
Y
R
A
N
GFKLGDVA
Q
S
M
V
I
R
DG
I
G
W
I
V
V
NNSH
V
I
F
A
I
DINTFKEV
G
R
I
T
GFTSP
R
Y
I
H
F
LSDE
K
A
Y
V
T
Q
I
WDY
R
I
F
I
I
N
PKTYEIT
G
Y
I
E
C
P
DMDMES
G
S
T
E
Q
M
V
Q
Y
GK
Y
V
Y
V
N
C
W
SY
Q
N
R
I
L
K
I
D
TETDKVV
D
E
L
T
I
G
IQPT
S
L
V
M
D
KYN
K
M
W
T
I
T
DGG
Y
E
G
S
P
Y
G
----
Y
E
A
P
S
-
L
Y
R
I
--------
D
A
E--
T
F
T
V
-
E
K
-----
Q
F
K
F
K
LGDWP
S
E
V
Q
L
N
GTRD
T
L
Y
W
I
N
N
D
I
W
R
M
P
VEADRVPVRPFLEFRDTKYY
G
L
T
V
NPNNG
E
V
Y
V
A
D
AIDYQ
Q
Q
G
I
V
Y
R
Y
S
PQGKLI
D
E
F
Y
V
G
I
IPG
A
F
C
W
K
L
E
H
H
H
H
H----------------------------------------------------------
3
HHSearch
47.19
35%
-40
- C10 -
4TT0
3
LTP_HHV11
A:
[114-131]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
----
L
L
T
R
Q
-
G
A
R
L
--------
Q
A
---
L
F
D
T
-
R
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
40.53
11%
14
- C10 -
4IMY
-
AFF4_HUMAN
G:
[36-68]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L
F
A
E
P
Y
K
V
T
S
----
K
E
D
K
L
-
S
S
R
I
--------
Q
S
M
L
G
N
Y
D
E
-
M
K
-----
D
F
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
35.98
14%
15
- C10 -
2JPM
-
LCGB_LACLL
A:
[1-35]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
W
G
W
L
A
----
W
V
D
P
A
-
Y
E
F
I
K
GFGKGAI
K
E
---
G
N
K
D
-
K
W
-----
K
N
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
35.78
22%
34
- C10 -
2E62
-
?
A:
[4-21]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
----
S
S
G
N
G
-
M
D
----------
E
E
---
Q
R
Q
K
-
R
R
-----
R
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
34.99
33%
-0
- C10 -
3WOA
-
MALE_ECOLI (first)
A:
[15-29]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-
A
R
R
L
--------
K
A
---
I
Y
E
K
-
K
K
-----
N
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
28.87
40%
27
- C5 -
3QNK
-
?
A:
[438-447]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
---
R
K
E
R
-
R
I
-----
E
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
27.92
30%
36
- C4 -
3IHV
-
?
A:
[454-463]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
---
R
K
E
R
-
S
Y
-----
E
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
26.96
3%
48
- C7 -
1ZFO
1
LASP1_PIG
A:
[4-31]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MN
P
N
C
A
R
C
G
----
K
I
V
Y
P
-
T
E
K
V
--------
N
C
---
L
D
K
F
W
H
K
-----
A
C
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
20.51
17%
-10
- C1 -
3MVU
1
?
A:
[2-13]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
E
P
----
Y
G
K
A
F
--
S
L
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------