@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0373: (2016-01-02 )
MFGSNDDKKAPQGGEKKGLFGWWRKKPQAGEQPADQPVEPVSETAAAEQRAPADDVAQSLTEQPGRQQPSAAEPAEPPAPVAEAPLAGDEPASAEEHSPRPEAPVAQPEPILAAEPEPEPEPEPEPEPEPVAPLAAAPAVSEPATRPGFFARLRQGLSKTSASIGEGMASLFLGRKEIDDDLLDDIETRLLTADVGVEATTLIVQNLTKRVARKELADSGALYKALQEELASLLRPVEQPLQVDVAREPYVILVVGVNGVGKTTTIGKLAKKLQLEGKKVMLAAGDTFRAAAVEQLQVWGERNRIPVIAQHTGADSASVIFDAVQAAKARGIDVLIADTAGRLHTKDNLMEELKKVRRVIGKLDETAPHEVLLVLDAGTGQNAINQAKQFNLAVELTGLALTKLDGTAKGGVIFALAKQFGLPIRYIGVGEGIDDLRTFEADAFVQALFAERENA
Atome Classification :
(47 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170..-.-..----.-.-----------180---...----....190.......200.......210..----..--------...--------220---...-.....230..---...-------..--240.-..-----------..-...-250.......260.......270.-......280.......290.......300....-...310-.-......320.......330.......340......-.350--.........360.......370.......380.......390.......400.......410.......420.......430.......440.......450...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MFGSNDDKKAPQGGEKKGL
F
G
W
WRKKPQAGEQPADQPVEP
V
S
E
T
A
A
AEQRA
P
A
D
D
V
A
Q
S
L
T
EQPGRQQPSAAEPAEPPAPVAEAPLAGDEPASAEEHSPRPEAPVAQPEPILAAEPEPEPEPEPEPEPEPVAPLAAAPAVSEPATR
P
G
F
F
A
R
L
R
Q
G
L
S
K
T
S
A
S
I
G
E
G
M
A
S
L
F
LG-R-KE----I-
D
-----------
D
D
L
---
L
D
D
----
I
E
T
R
L
L
T
ADVG
V
E
A
T
T
L
I
V
Q
N
L
T
K
R
V
A
R
K
----
E
L--------ADS--------
G
A
----
L
Y
K
-
A
L
Q
E
E
L
A
S
L
L
---
R
PV-------EQ--P-LQ-VD-----------VA-RE
P
-
Y
V
I
L
V
V
GVNGVGKT
T
T
I
G
K
L
A
K
K
L
-QLEG
K
K
V
M
L
AAGD
T
F
R
A
A
A
V
E
Q
L
Q
V
WGERNR
I
P
-
V
I
A
QHT-G-A
D
S
A
S
V
I
F
D
A
V
Q
A
A
KARG
I
D
V
L
I
ADTAGRLH
T
K
D
N
-
L
M
----
E
E
L
K
K
V
R
R
V
I
G
KLDETAP
H
E
V
L
L
V
L
DAGTG
Q
N
A
I
N
Q
A
K
Q
F
N
L
A
V
E
L
T
G
L
A
L
T
KLDGTAKG
G
V
I
F
A
L
A
K
QFGL
P
I
R
Y
I
GVGEG
I
D
D
L
R
T
F
E
A
D
A
F
V
Q
A
L
F
A
ERENA
84
HHSearch
97.11
67%
-118
- C6 -
2YHS
5
FTSY_ECOLI
A:
[188-495]
---------------------------------------------------------------------------------------------------------------------------------------------
E
K
P
T
K
E
G
F
F
A
R
L
K
R
S
L
L
K
T
K
E
N
L
G
S
G
F
I
S
L
F
R
G
-
K
--
K
----
I
-
D
-----------
D
D
L
---
F
E
E
----
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
--------
R
D
A
--------
E
A
----
L
Y
G
-
L
L
K
E
E
M
G
E
I
L
---
A
K
V
-------
D
E
--
P
-
L
N
-
V
------------
E
G
-
K
A
P
-
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
-
V
I
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
-
L
M
----
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
----
1
PsiBlast_PDB
96.76
65%
-119
- C6 -
2YHS
5
FTSY_ECOLI
A:
[188-494]
---------------------------------------------------------------------------------------------------------------------------------------------
E
K
P
T
K
E
G
F
F
A
R
L
K
R
S
L
L
K
T
K
E
N
L
G
S
G
F
I
S
L
F
R
G
-
K
-
K
-----
I
-
D
-----------
D
D
L
---
F
E
E
----
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
--------
R
D
A
--------
E
A
----
L
Y
G
-
L
L
K
E
E
M
G
E
I
L
---
A
K
V
-------
D
E
--
P
-
L
N
-
V
E
------------
G
-
K
A
P
-
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
-
V
I
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
-
L
M
----
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
----
3
PsiBlast_PDB
94.75
66%
-121
- C6 -
2QY9
-
FTSY_ECOLI
A:
[196-495]
-----------------------------------------------------------------------------------------------------------------------------------------------------
F
A
R
L
K
R
S
L
L
K
T
K
E
N
L
G
S
G
F
I
S
L
F
R
G
-
K
-
K
-----
I
-
D
-----------
D
D
L
---
F
E
E
----
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
--------
R
D
A
--------
E
A
----
L
Y
G
-
L
L
K
E
E
M
G
E
I
L
---
A
K
V
-------
D
E
--
P
-
L
N
-
V
E
------------
G
-
K
A
P
-
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
-
V
I
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
-
L
M
----
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
----
4
PsiBlast_PDB
93.45
67%
-120
- C6 -
1FTS
-
FTSY_ECOLI
A:
[201-494]
----------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
L
L
K
T
K
E
N
L
G
S
G
F
I
S
L
F
R
G
-
K
-
K
-----
I
-
D
-----------
D
D
L
---
F
E
E
----
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
--------
R
D
A
--------
E
A
----
L
Y
G
-
L
L
K
E
E
M
G
E
I
L
---
A
K
V
-------
D
E
--
P
-
L
N
-
V
E
------------
G
-
K
A
P
-
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
-
V
I
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
-
L
M
----
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
----
22
PsiBlast_CBE
91.85
68%
-114
- C6 -
4C7O
5
FTSY_ECOLI
D:
[2-277]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
----
I
-
D
-----------
D
D
L
---
F
E
E
----
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
--------
R
D
A
--------
E
A
----
L
Y
G
-
L
L
K
E
E
M
G
E
I
L
---
A
K
V
-------
D
E
--
P
-
L
N
-
V
E
------------
G
-
K
A
P
-
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
-
V
I
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
-
L
M
----
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
E
---
5
PsiBlast_PDB
91.84
67%
-118
- C6 -
3ZN8
-
FTSY_ECOLI
D:
[1-294]
----------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
L
L
K
T
K
E
N
L
G
S
G
F
I
S
L
F
R
G
-
K
-
K
-----
I
-
D
-----------
D
D
L
---
F
E
E
----
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
--------
R
D
A
--------
E
A
----
L
Y
G
-
L
L
K
E
E
M
G
E
I
L
---
A
K
V
-------
D
E
--
P
-
L
N
-
V
E
------------
G
-
K
A
P
-
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
-
V
I
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
-
L
M
----
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
----
2
PsiBlast_PDB
89.67
67%
-112
- C6 -
2XXA
3
FTSY_ECOLI
B:
[20-302]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
L
F
R
G
-
K
-
K
-----
I
-
D
-----------
D
D
L
---
F
E
E
----
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
--------
R
D
A
--------
E
A
----
L
Y
G
-
L
L
K
E
E
M
G
E
I
L
---
A
K
V
-------
D
E
--
P
-
L
N
-
V
E
------------
G
-
K
A
P
-
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
-
V
I
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
-
L
M
----
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
E
D
--
6
PsiBlast_PDB
89.42
68%
-114
- C6 -
4C7O
4
FTSY_ECOLI
B:
[5-275]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-----------
D
D
L
---
F
E
E
----
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
--------
R
D
A
--------
E
A
----
L
Y
G
-
L
L
K
E
E
M
G
E
I
L
---
A
K
V
-------
D
E
--
P
-
L
N
-
V
E
------------
G
-
K
A
P
-
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
-
V
I
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
-
L
M
----
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
-----
21
PsiBlast_CBE
89.31
67%
-112
- C6 -
2XXA
3
FTSY_ECOLI
D:
[20-302]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
L
F
R
G
-
K
-
K
-----
I
-
D
-----------
D
D
L
---
F
E
E
----
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
R
K
----
Q
L
--------
R
D
A
--------
E
A
----
L
Y
G
-
L
L
K
E
E
M
G
E
I
L
---
A
K
V
-------
D
E
--
P
-
L
N
-
V
E
------------
G
-
K
A
P
-
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
-
V
I
A
Q
H
T
-
G
-
A
D
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
-
L
M
----
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
E
D
--
23
PsiBlast_CBE
86.85
51%
-110
- C6 -
1VMA
1
?
B:
[14-306]
---------------------------------------------------------------------------------------------------------------------------------------------------
G
L
F
D
F
L
K
K
G
L
Q
K
T
K
E
T
F
F
G
R
V
V
K
L
L
K
G
-
K
-
K
-----
L
-
D
-----------
D
E
T
---
R
E
E
----
L
E
E
L
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
E
E
K
-------------------
D
G
--------
D
A
----
L
-
E
-
S
L
K
E
I
I
L
E
I
L
---
N
F
------------
D
-
T
K
-
L
N
-----------
V
P
-
P
E
P
P
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
-
V
D
E
G
K
S
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
R
V
G
A
T
-
V
I
S
H
S
E
-
G
-
A
D
P
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
-
L
M
----
E
E
L
R
K
V
H
R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
S
E
----
95
HHSearch
86.78
52%
-106
- C6 -
1VMA
1
?
A:
[13-305]
--------------------------------------------------------------------------------------------------------------------------------------------------
M
G
L
F
D
F
L
K
K
G
L
Q
K
T
K
E
T
F
F
G
R
V
V
K
L
L
K
G
---
K
K
----
L
-
D
-----------
D
E
T
---
R
E
E
----
L
E
E
L
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
E
E
K
D
G
----------------------------
D
----
A
L
E
-
S
L
K
E
I
I
L
E
I
L
---
N
F
D
-------
T
---
K
-
L
N
--
V
-----------
P
P
-
E
P
P
-
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
-
V
D
E
G
K
S
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
R
V
G
A
T
-
V
I
S
H
S
E
-
G
-
A
D
P
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
-
L
M
----
E
E
L
R
K
V
H
R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
S
E
----
7
PsiBlast_PDB
86.62
51%
-110
- C6 -
1VMA
1
?
A:
[14-306]
---------------------------------------------------------------------------------------------------------------------------------------------------
G
L
F
D
F
L
K
K
G
L
Q
K
T
K
E
T
F
F
G
R
V
V
K
L
L
K
G
-
K
-
K
-----
L
-
D
-----------
D
E
T
---
R
E
E
----
L
E
E
L
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
E
E
K
-------------------
D
G
--------
D
A
----
L
-
E
-
S
L
K
E
I
I
L
E
I
L
---
N
F
------------
D
-
T
K
-
L
N
-----------
V
P
-
P
E
P
P
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
-
V
D
E
G
K
S
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
R
V
G
A
T
-
V
I
S
H
S
E
-
G
-
A
D
P
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
-
L
M
----
E
E
L
R
K
V
H
R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
S
E
----
86
HHSearch
84.22
43%
-116
- C6 -
3B9Q
1
CFTSY_ARATH
A:
[2-302]
-------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
F
S
G
F
S
K
T
R
E
N
L
A
V
-
I
D
E
L
L
L
F
-
W
N
L
A
----
E
-
T
-----------
D
R
V
---
L
D
E
----
L
E
E
A
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
D
I
M
S
G
----
K
L
--------
K
S
G
--------
S
E
----
I
K
D
-
A
L
K
E
S
V
L
E
M
L
---
A
K
---------
S
KT
E
-
L
Q
--
L
-----------
G
F
-
R
K
P
-
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
-
K
N
E
G
T
K
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
R
T
G
C
E
-
I
V
V
A
E
---K
A
K
A
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
-
L
M
----
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
S
-----
85
HHSearch
83.97
42%
-116
- C6 -
2OG2
2
CFTSY_ARATH
A:
[55-359]
---------------------------------------------------------------------------------------------------------------------------------------------------
S
D
V
E
K
V
F
S
G
F
S
K
T
R
E
N
L
A
V
-
I
D
E
L
L
L
F
W
N
-
L
A
----
E
-
T
-----------
D
R
V
---
L
D
E
----
L
E
E
A
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
D
I
M
S
G
----
K
L
--------
K
S
G
--------
S
E
----
I
K
D
-
A
L
K
E
S
V
L
E
M
L
---
A
K
K
---------T-
E
-
L
Q
-
L
------------
G
F
-
R
K
P
-
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
-
K
N
E
G
T
K
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
R
T
G
C
E
-
I
V
V
A
E
G
D
K
-
A
K
A
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
-
L
M
----
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
S
-----
24
PsiBlast_CBE
83.84
48%
-99
- C6 -
2Q9C
6
FTSY_THEAQ
B:
[2-302]
---------------------------------------------------------------------------------------------------------------------------------------------------
G
F
F
D
R
L
K
A
G
L
A
K
T
R
E
R
L
---
L
K
A
I
P
W
G
-
G
-
N
L
----
E
-
E
-----------
V
L
E
---
E
L
E
----
M
A
L
L
--
A
A
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
-
R
A
S
G
R
K
----
D
L
--------
K
E
-------------------
A
V
K
E
K
L
V
G
M
L
---
E
P
D
------------------KPKP-------
V
E
-
P
K
G
-
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
Q
G
P
E
-
G
-
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
-
L
M
----
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
D
----
26
PsiBlast_CBE
83.38
48%
-98
- C6 -
2Q9A
12
FTSY_THEAQ
B:
[2-302]
---------------------------------------------------------------------------------------------------------------------------------------------------
G
F
F
D
R
L
K
A
G
L
A
K
T
R
E
R
L
---
L
K
A
I
P
W
G
-
G
-
N
L
----
E
-
E
-----------
V
L
E
---
E
L
E
----
M
A
L
L
--
A
A
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
-
R
A
S
G
R
K
----
D
L
--------
K
E
-------------------
A
V
K
E
K
L
V
G
M
L
---
E
P
D
------------------KPKP-------
V
E
-
P
K
G
-
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
Q
G
P
E
-
G
-
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
-
L
M
----
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
D
----
98
HHSearch
82.66
50%
-116
* C6 *
1RJ9
3
FTSY_THEAQ
A:
[27-303]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
----
L
-------------
E
E
V
---
L
E
E
----
L
E
M
A
L
L
A
A
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
S
G
R
---------------------------
K
D
----
L
K
E
-
A
V
K
E
K
L
V
G
M
L
---
E
P
D
E
R
R
A
T
L
R
K
L
--
G
-
F
N
-
P
Q
KPKP-------
V
E
-
P
K
G
-
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
Q
G
P
E
-
G
-
T
D
S
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
-
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
----
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
-----
16
PsiBlast_PDB
82.13
48%
-95
- C6 -
2Q9C
8
FTSY_THEAQ
A:
[2-302]
---------------------------------------------------------------------------------------------------------------------------------------------------
G
F
F
D
R
L
K
A
G
L
A
K
T
R
E
R
L
---
L
K
A
I
P
W
G
-
G
-
N
L
----
E
-
E
-----------
V
L
E
---
E
L
E
----
M
A
L
L
--
A
A
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
-
R
A
S
G
R
K
----
D
L
--------
K
E
-------------------
A
V
K
E
K
L
V
G
M
L
---
E
P
D
-------
E
R
--
R
-
A
T
-
L
R
K
L
GFNPQKPKP
V
E
-
P
K
G
-
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
Q
G
P
E
-
G
-
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
-
L
M
----
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
D
----
8
PsiBlast_PDB
82.04
41%
-118
- C6 -
2OG2
2
CFTSY_ARATH
A:
[55-359]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
V
E
K
V
F
S
G
F
S
K
-
T
-
R
E
N
L
A
V
I
-
D
E
L
L
L
F
WNLAE
T
D
R
V
---
L
D
E
----
L
E
E
A
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
E
D
I
M
S
G
----
K
L
--------
K
S
G
--------
S
E
----
I
K
D
-
A
L
K
E
S
V
L
E
M
L
---
A
K
K
-------------
T
E
-
L
Q
-----------
L
G
F
R
K
P
-
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
-
K
N
E
G
T
K
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
R
T
G
C
E
I
V
V
A
E
G
D
-
K
-
A
K
A
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
-
L
M
----
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
S
-----
18
PsiBlast_PDB
81.96
52%
-118
- C6 -
2IYL
3
FTSY_THEAQ
D:
[23-282]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
-
R
A
S
G
R
K
----
D
L
--------
K
E
-------------------
A
V
K
E
K
L
V
G
M
L
---
E
P
D
-------------
A
T
-
L
R
KLGFNPQKP--
V
E
-
P
K
G
-
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
------
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
Q
G
P
E
-
G
-
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
-
L
M
----
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
--
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
D
----
15
PsiBlast_PDB
81.90
48%
-98
- C6 -
2Q9B
12
FTSY_THEAQ
A:
[2-302]
---------------------------------------------------------------------------------------------------------------------------------------------------
G
F
F
D
R
L
K
A
G
L
A
K
T
R
E
R
L
---
L
K
A
I
P
W
G
-
G
-
N
L
----
E
-
E
-----------
V
L
E
---
E
L
E
----
M
A
L
L
--
A
A
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
-
R
A
S
G
R
K
----
D
L
--------
K
E
-------------------
A
V
K
E
K
L
V
G
M
L
---
E
P
D
-------
E
R
--
R
-
A
T
-
L
R
K
L
GFNPQKPKP
V
E
-
P
K
G
-
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
Q
G
P
E
-
G
-
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
-
L
M
----
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
-----
25
PsiBlast_CBE
81.89
48%
-102
- C6 -
2Q9B
13
FTSY_THEAQ
B:
[2-302]
---------------------------------------------------------------------------------------------------------------------------------------------------
G
F
F
D
R
L
K
A
G
L
A
K
T
R
E
R
L
---
L
K
A
I
P
W
G
-
G
-
N
L
----
E
-
E
-----------
V
L
E
---
E
L
E
----
M
A
L
L
--
A
A
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
-
R
A
S
G
-------
L
--------
K
E
-------------------
A
V
K
E
K
L
V
G
M
L
---
E
P
D
------------------KP
K
P
-------
V
E
-
P
K
G
-
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
Q
G
P
E
-
G
-
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
-
L
M
----
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
D
----
19
PsiBlast_PDB
81.10
52%
-109
- C6 -
2J7P
7
FTSY_THEAQ
D:
[22-281]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
-
R
A
S
G
R
K
----
D
L
--------
K
E
-------------------
A
V
K
E
K
L
V
G
M
L
---
E
P
-------------------KP---------
V
E
-
P
K
G
-
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
Q
G
P
E
-
G
-
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
-
L
M
----
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
-----
29
PsiBlast_CBE
80.05
52%
-108
- C6 -
2J7P
9
FTSY_THEAQ
E:
[22-281]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
-
R
A
S
G
R
K
----
D
L
--------
K
E
-------------------
A
V
K
E
K
L
V
G
M
L
---
E
P
-------------------P----------
V
E
-
P
K
G
-
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
Q
G
P
E
-
G
-
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
-
L
M
----
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
-----
11
PsiBlast_PDB
79.58
48%
-98
- C6 -
1RJ9
3
FTSY_THEAQ
A:
[27-302]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
----
E
-
E
-----------
V
L
E
---
E
L
E
----
M
A
L
L
--
A
A
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
-
R
A
S
G
R
K
----
D
L
--------
K
E
-------------------
A
V
K
E
K
L
V
G
M
L
---
E
P
D
-------
E
R
--
R
-
A
T
-
L
R
K
L
G
F
N
P
Q
KPKP
V
E
-
P
K
G
-
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
Q
G
P
E
-
G
-
T
D
S
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
-
L
M
----
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
-----
12
PsiBlast_PDB
79.45
48%
-102
- C6 -
1OKK
8
FTSY_THEAQ
D:
[20-301]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
P
W
G
-
G
-
N
L
----
E
-
E
-----------
V
L
E
---
E
L
E
----
M
A
L
L
--
A
A
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
-
R
A
S
G
R
K
----
D
L
--------
K
E
-------------------
A
V
K
E
K
L
V
G
M
L
---
E
P
-------------------P----------
V
E
-
P
K
G
-
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
-
Q
N
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
-
V
I
Q
G
P
E
-
G
-
T
D
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
-
L
M
----
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
-----
94
HHSearch
74.82
36%
-102
- C6 -
3DM5
10
SRP54_PYRFU
A:
[29-297]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
L
---
V
R
D
----
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
KPPA
G
I
--------
S
K
K
--------
E
H
----
I
I
K
-
I
V
Y
E
E
L
T
K
F
L
---
G
T
E
-------
A
K
--
P
-
I
E
--------------
I
K
-
E
K
P
-
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
-
Q
K
R
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
-
V
F
G
N
P
Q
-
E
-
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
-
L
I
----
E
E
M
K
Q
I
S
N
V
I
------
H
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
35
PsiBlast_CBE
74.56
36%
-106
- C6 -
3DM5
10
SRP54_PYRFU
A:
[30-295]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
---
V
R
D
----
I
Q
R
A
L
I
Q
A
D
V
N
V
R
----
L
V
L
Q
L
T
R
E
I
Q
R
R
----
A
L
E
EKPPAGI
S
K
K
--------
E
H
----
I
I
K
-
I
V
Y
E
E
L
T
K
F
L
---
G
T
E
-------
A
K
--
P
----
I
E
-----------
I
K
-
E
K
P
-
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
-
Q
K
R
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
-
V
F
G
N
P
Q
-
E
-
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
-
H
K
E
D
K
A
L
I
----
E
E
M
K
Q
I
S
N
V
I
------
H
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
34
PsiBlast_CBE
74.50
36%
-107
- C6 -
3DM5
9
SRP54_PYRFU
B:
[30-295]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
---
V
R
D
----
I
Q
R
A
L
I
Q
A
D
V
N
V
R
----
L
V
L
Q
L
T
R
E
I
Q
R
R
----
A
L
E
EKPPAGI
S
K
K
--------
E
H
----
I
I
K
-
I
V
Y
E
E
L
T
K
F
L
---
G
T
E
-------
A
K
--
P
----
I
E
-----------
I
K
-
E
K
P
-
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
-
Q
K
R
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
-
V
F
G
N
P
Q
-
E
-
K
D
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
-
H
K
E
D
K
A
L
I
----
E
-
M
K
Q
I
S
N
V
I
------
H
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
52
PsiBlast_CBE
74.38
35%
-94
- C6 -
2J7P
10
SRP54_THEAQ
A:
[3-282]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
-
G
-
R
-
G
R
----
I
T
E
-----------
E
D
L
K
A
T
L
R
E
----
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
--------
L
E
S
LT
P
A
E
V
I
L
A
T
----
V
Y
E
-
A
L
K
E
A
L
G
G
E
A
---
R
------------------
L
P
-----------
V
L
-
K
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
-
L
M
----
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
----
90
HHSearch
74.21
43%
-110
- C6 -
3E70
3
?
C:
[53-324]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
A
---
L
D
E
----
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
----
K
V
RIG-------
G
--------
K
I
----
I
E
E
-
A
V
K
E
A
V
S
E
I
L
---
E
T
S
-------
R
R
I-
D
L
I
E
E
I
R
-----------
K
A
-
E
K
P
-
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
-
K
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
-
V
I
K
H
S
Y
-
G
-
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
-
L
M
----
D
E
M
K
K
I
A
R
V
T
------
K
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
-----
30
PsiBlast_CBE
73.93
43%
-104
- C6 -
3E70
3
?
C:
[53-324]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
A
---
L
D
E
----
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
----
K
V
RIG----------------
G
K
----
I
I
E
E
A
V
K
E
A
V
S
E
I
L
ETS
R
R
I
-------
D
L
--
I
-
E
E
-
I
R
-----------
K
A
-
E
K
P
-
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
-
K
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
-
V
I
K
H
S
Y
-
G
-
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
-
L
M
----
D
E
M
K
K
I
A
R
V
------
T
K
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
-----
32
PsiBlast_CBE
73.92
43%
-104
- C6 -
3DMD
6
?
A:
[53-324]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
A
---
L
D
E
----
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
----
K
V
R
IG-----
T
D
K
--------
G
K
----
I
I
E
E
A
V
K
E
A
V
S
E
I
L
ETS
R
R
I
-------
D
L
--
I
-
E
E
-
I
R
-----------
K
A
-
E
K
P
-
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
-
K
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
-
V
I
K
H
S
Y
-
G
-
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
-
L
M
----
D
E
M
K
K
I
A
R
V
------
T
K
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
-----
57
PsiBlast_CBE
73.91
35%
-92
- C6 -
1NG1
12
SRP54_THEAQ
A:
[2-282]
------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
-
G
-
R
-
G
R
----
I
T
E
-----------
E
D
L
K
A
T
L
R
E
----
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
--------
L
E
S
LT
P
A
E
V
I
L
A
T
----
V
Y
E
-
A
L
K
E
A
L
G
G
E
A
---
R
------------------
L
P
-----------
V
L
-
K
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
-
L
M
----
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
----
51
PsiBlast_CBE
73.87
35%
-96
- C6 -
2J7P
7
SRP54_THEAQ
B:
[4-282]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
-
G
-
R
-
G
R
----
I
T
E
-----------
E
D
L
K
A
T
L
R
E
----
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
--------
L
E
S
LT
P
A
E
V
I
L
A
T
----
V
Y
E
-
A
L
K
E
A
L
G
G
E
A
---
R
------------------
L
P
-----------
V
L
-
K
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
-
L
M
----
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
----
64
PsiBlast_CBE
73.57
35%
-94
- C6 -
1O87
7
SRP54_THEAQ
B:
[2-282]
------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
-
G
-
R
-
G
R
----
I
T
E
-----------
E
D
L
KAT
L
R
E
----
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
--------
L
E
S
LTPAEVIL
A
T
----
V
Y
E
-
A
L
K
E
A
L
G
G
E
A
---
R
------------------
L
P
-----------
V
L
-
K
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
-
L
M
----
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
---
60
PsiBlast_CBE
73.35
35%
-92
- C6 -
1JPJ
1
SRP54_THEAQ
A:
[2-282]
------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
-
G
-
R
-
G
R
----
I
T
E
-----------
E
D
L
K
A
T
L
R
E
----
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
--------
L
E
S
LT
P
A
E
V
I
L
A
T
----
V
Y
E
-
A
L
K
E
A
L
G
G
E
A
---
R
------------------
L
P
-----------
V
L
-
K
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
-
L
M
----
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
----
56
PsiBlast_CBE
73.30
35%
-93
- C6 -
1OKK
16
SRP54_THEAQ
A:
[4-282]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
-
G
-
R
-
G
R
----
I
T
E
-----------
E
D
L
K
A
T
L
R
E
----
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
--------
L
E
S
LT
P
A
E
V
I
L
A
T
----
V
Y
E
-
A
L
K
E
A
L
G
G
E
A
---
R
------------------
L
P
-----------
V
L
-
K
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
-
L
M
----
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
-----
37
PsiBlast_CBE
73.29
33%
-101
- C6 -
4C7O
5
SRP54_ECOLI
C:
[2-288]
-----------------------------------------------------------------------------------------------------------------------------------------------------
F
D
N
L
T
D
R
L
S
R
T
L
R
N
I
S
--------
G
-
R
-
G
R
----
L
-
T
-----------
E
D
N
---
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
----
E
V
--------
N
K
S
--------
L
T
P
G
Q
E
F
V
K
-
I
V
R
N
E
L
V
A
A
M
---
G
E
E
-------
N
Q
--
T
-
L
N
-
L
------------
A
A
-
Q
P
P
-
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
-
F
F
P
S
D
V
-
G
-
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
-
M
M
----
D
E
I
K
Q
V
H
A
S
I
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
---
20
PsiBlast_PDB
73.10
43%
-102
- C6 -
3DMD
4
?
B:
[53-324]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
A
---
L
D
E
----
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
----
K
V
R
IG-----
T
D
K
--------
G
K
----
I
I
E
E
A
V
K
E
A
V
S
E
I
L
ETS
R
R
I
-------
D
L
--
I
-
E
E
-
I
R
-----------
K
A
-
E
K
P
-
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
-
K
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
-
V
I
K
H
S
Y
-
G
-
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
-
L
M
----
D
E
M
K
K
I
A
R
V
------
T
K
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
-----
59
PsiBlast_CBE
72.90
35%
-94
- C6 -
1JPN
4
SRP54_THEAQ
A:
[2-282]
------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
-
G
-
R
-
G
R
----
I
T
E
-----------
E
D
L
K
A
T
L
R
E
----
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
--------
L
E
S
LT
P
A
E
V
I
L
A
T
----
V
Y
E
-
A
L
K
E
A
L
G
G
E
A
---
R
------------------
L
P
-----------
V
L
-
K
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
-
L
M
----
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
--
65
PsiBlast_CBE
72.68
35%
-95
- C6 -
1O87
7
SRP54_THEAQ
A:
[2-282]
------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
-
G
-
R
-
G
R
----
I
T
E
-----------
E
D
L
K
A
T
L
R
E
----
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
--------
L
E
S
LT
P
A
E
V
I
L
A
T
----
V
Y
E
-
A
L
K
E
A
L
G
G
E
A
---
R
------------------
L
P
-----------
V
L
-
K
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
-
L
M
----
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
---
31
PsiBlast_CBE
72.40
43%
-106
- C6 -
3DMD
7
?
C:
[53-324]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
A
---
L
D
E
----
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
----
K
V
R
IG-----
T
D
K
--------
G
K
----
I
I
E
E
A
V
K
E
A
V
S
E
I
L
ETS
R
R
I
-------
D
L
--
I
-
E
E
-
I
R
-----------
K
A
-
E
K
P
-
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
-
K
N
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
-
V
I
K
H
S
Y
-
G
-
A
D
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
-
L
M
----
D
E
M
K
K
I
A
R
V
------
T
K
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
-----
58
PsiBlast_CBE
71.92
35%
-94
- C6 -
1JPN
4
SRP54_THEAQ
B:
[2-282]
------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
-
G
-
R
-
G
R
----
I
T
E
-----------
E
D
L
KAT
L
R
E
----
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
--------
L
E
S
LTPAEVIL
A
T
----
V
Y
E
-
A
L
K
E
A
L
G
G
E
A
---
R
------------------
L
P
-----------
V
L
-
K
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
-
L
M
----
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
---
38
PsiBlast_CBE
71.86
33%
-99
- C6 -
4C7O
4
SRP54_ECOLI
A:
[4-288]
-------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
T
D
R
L
S
R
T
L
R
N
I
S
--------
G
-
R
-
G
R
----
L
-
T
-----------
E
D
N
---
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
----
E
V
--------
N
K
S
--------
L
T
P
G
Q
E
F
V
K
-
I
V
R
N
E
L
V
A
A
M
---
G
E
E
-------
N
Q
--
T
-
L
N
-
L
------------
A
A
-
Q
P
P
-
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
-
F
F
P
S
D
V
-
G
-
Q
K
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
-
M
M
----
D
E
I
K
Q
V
H
A
S
I
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
-----
46
PsiBlast_CBE
71.53
35%
-92
- C6 -
2NG1
4
SRP54_THEAQ
A:
[1-281]
------------------------------------------------------------------------------------------------------------------------------------------------------------
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
-
G
-
R
-
G
R
----
I
T
E
-----------
E
D
L
K
A
T
L
R
E
----
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
--------
L
E
S
LT
P
A
E
V
I
L
A
T
----
V
Y
E
-
A
L
K
E
A
L
G
G
E
A
---
R
------------------
L
P
-----------
V
L
-
K
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
-
L
M
----
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
----
47
PsiBlast_CBE
70.89
35%
-98
- C6 -
1RJ9
3
SRP54_THEAQ
B:
[14-282]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
L
R
-
G
-
R
-
G
R
----
I
T
E
-----------
E
D
L
K
A
T
L
R
E
----
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
----
Q
V
--------
L
E
S
LT
P
A
E
V
I
L
A
T
----
V
Y
E
-
A
L
K
E
A
L
G
G
E
A
---
R
------------------
L
P
-----------
V
L
-
K
D
R
-
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
-
K
G
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
-
V
L
E
V
M
D
-
G
-
E
S
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
-
L
M
----
G
E
L
A
R
L
K
E
V
L
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
---