@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA3746: (2016-02-20 )
MFENLTDRLSQTLRHVTGKAKLTEDNIKDTLREVRMALLEADVALPVVKDFVNKVKERAVGTEVSKSLTPGQAFVKIVRAELEELMGAANEDLALSVAPPAVILMAGLQGAGKTTTAGKLARFLKERKKKSVMVVSADVYRPAAIKQLETLAGEVGVTFFPSDVSQKPVAIAEAAIREARLKFIDVVIVDTAGRLHIDADMMDEIKQVHAAIKPAETLFVVDAMTGQDAANTAKAFNDALPLTGVVLTKVDGDARGGAALSVRAITGKPIKFLGMGEKSEALDPFHPDRVASRILGMGDVLSLIEQAEQNLDRDKAEKLAKKIKKGKGFDLEDFRDQLQQMKNMGGLGGLMDKLPMLGGVNLAQMGNAQGAAEKQFKQMEAIINSMTPGERRDPEMISGSRKRRIALGSGTQVQDVGRLIKQHKQMQKMMKKVTAKGGMAKMMRGMGSMFPGGMPKL
Atome Classification :
(46 SA)
.........10........-----------20........30........40........50........60...-.....70........80........90------.-.-..--..-----.---..--100.......110.......120.......130.......140.......150.......160.....-..170.......180.......190.......200.......210----.------.------.------......220.......230.......240..-.....250.......260.......270.......280.......290.......300....-...310...-....320.......330.......340.......350.......360.......370.........380.......390.......400.......410.......420.......430.......440.......450.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MF
E
N
L
T
D
R
L
S
Q
T
L
R
H
VTGK-----------AKL
T
E
D
N
I
K
D
T
L
R
E
V
R
M
A
L
L
EADVA
L
P
V
V
K
D
F
V
N
K
V
K
E
R
AVGT
E
V
-
S
KSLT
P
G
Q
A
F
V
K
I
V
R
A
E
L
E
E
L
MGAAN-------E-
D
-
L
A
--
L
S-----V---AP--P
A
V
I
L
M
AGLQGAGKTT
T
A
G
K
L
A
R
F
L
K
E
RKKK
S
V
M
V
V
SADVYR
P
A
A
I
K
Q
L
E
T
L
A
GEVG
V
T
FFPSDVSQK-
P
V
A
I
A
E
A
A
I
R
E
A
R
L
K
F
I
D
V
V
I
VDTA
G
R
L
H
I
D
A
D
M
M
D
E
I
K
Q
V
H
A
------A------I------K------PA
E
T
L
F
V
V
DAMTGQDAA
N
T
A
K
A
F
NDALPL
T
G
-
V
V
L
T
KVDGDARG
G
A
A
L
S
V
R
AITGK
P
I
K
F
L
GMGEKSEALDPF
H
P
D
R
V
A
S
R
I
LG
M
G
D
V
L
S
L
I
E
Q
-
A
E
Q
NL
D
R
D
K
-
A
E
K
L
A
K
K
I
KKGKGF
D
L
E
D
F
R
D
Q
L
Q
Q
M
K
NMGGL
G
G
L
M
D
KLPMLGGV
N
L
A
QMGNAQ
G
--
A
A
E
K
Q
F
K
Q
M
E
A
I
I
N
SMTPGERR
D
P
E
MISGSR
K
R
R
I
ALGSGT
Q
V
Q
D
V
G
R
L
I
K
Q
H
K
Q
M
Q
K
M
M
K
K
V
TAKG
G
M
A
K
M
M
R
G
M
G
SMFPGGMPKL
68
HHSearch
92.67
72%
-104
- C- -
2XXA
3
SRP54_ECOLI
A:
[4-432]
---
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
-
G
H
E
V
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
-------
Q
-
T
-
L
N
--
L
A
-----
A
---
Q
P
--
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
-
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
------
S
------
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
-
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
D
V
L
S
L
I
E
D
-
I
E
S
K
V
D
R
A
Q
-
A
E
K
L
A
S
K
L
K
K
G
D
G
F
D
L
N
D
F
L
E
Q
L
R
Q
M
K
N
M
G
G
M
A
S
L
M
G
K
--------------------
D
D
K
V
L
V
R
M
E
A
I
I
N
S
M
T
M
K
E
R
A
K
P
E
I
I
K
G
S
R
K
R
R
I
A
A
G
S
G
M
Q
V
Q
D
V
N
R
L
L
K
Q
F
D
D
M
Q
R
M
M
K
K
M
K
K
----------------------
1
PsiBlast_PDB
91.49
72%
-92
- C7 -
2XXA
3
SRP54_ECOLI
A:
[4-425]
---
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
-
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
-------
Q
-
T
-
L
N
--
L
A
-----
A
---
Q
P
--
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
-
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
------
S
------
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
-
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
D
V
L
S
L
I
E
D
-
I
E
S
K
V
D
R
A
Q
-
A
E
K
L
A
S
K
L
K
K
G
D
G
F
D
L
N
D
F
L
E
Q
L
R
Q
M
K
N
M
G
G
M
A
S
L
M
G
K
------------
D
--------
D
K
V
L
V
R
M
E
A
I
I
N
S
M
T
M
K
E
R
A
K
P
E
I
I
K
G
S
R
K
R
R
I
A
A
G
S
G
M
Q
V
Q
D
V
N
R
L
L
K
Q
F
D
D
M
Q
R
-----------------------------
21
PsiBlast_CBE
90.29
72%
-96
- C7 -
2XXA
3
SRP54_ECOLI
C:
[7-425]
------
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
-
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
-------
Q
-
T
-
L
N
--
L
A
-----
A
---
Q
P
--
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
-
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
------
S
------
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
-
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
D
V
L
S
L
I
E
D
-
I
E
S
K
V
D
R
A
Q
-
A
E
K
L
A
S
K
L
K
K
G
D
G
F
D
L
N
D
F
L
E
Q
L
R
Q
M
K
N
M
G
G
M
A
S
L
M
G
-------------
D
--------
D
K
V
L
V
R
M
E
A
I
I
N
S
M
T
M
K
E
R
A
K
P
E
I
I
K
G
S
R
K
R
R
I
A
A
G
S
G
M
Q
V
Q
D
V
N
R
L
L
K
Q
F
D
D
M
Q
R
-----------------------------
22
PsiBlast_CBE
87.12
78%
-104
- C7 -
4C7O
5
SRP54_ECOLI
C:
[2-298]
-
F
D
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
-
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
-------
Q
-
T
-
L
N
--
L
A
-----
A
---
Q
P
--
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
-
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
------
S
------
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
-
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
M
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
84.80
78%
-103
- C7 -
4C7O
4
SRP54_ECOLI
A:
[4-296]
---
N
L
T
D
R
L
S
R
T
L
R
N
I
S
G
R
-----------
G
R
L
T
E
D
N
V
K
D
T
L
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
-
N
K
S
L
T
P
G
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
E
E
N
-------
Q
-
T
-
L
N
--
L
A
-----
A
---
Q
P
--
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
Q
V
G
V
D
F
F
P
S
D
V
G
Q
K
-
P
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
------
S
------
I
------
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
-
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
R
I
A
S
R
I
L
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
77.01
35%
-86
- C7 -
3DM5
10
SRP54_PYRFU
A:
[2-435]
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
-----------
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
-
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
A
-------
K
-
P
-
I
E
--
I
K
---------
E
K
--
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
R
G
Y
K
-
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
G
N
P
Q
E
K
D
-
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
Q
I
S
N
------
V
------
I
------
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
-
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
F
K
E
L
E
K
E
V
E
I
-
K
E
E
D
I
E
R
F
L
R
G
K
-
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
----------------------
I
S
--
I
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
N
-
K
R
Q
L
S
-----------------
69
HHSearch
76.61
44%
-82
- C7 -
2FFH
7
SRP54_THEAQ
A:
[1-418]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
-
G
K
Q
V
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
E
A
---------
R
-
L
---
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
-
K
G
R
R
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
A
S
L
A
E
K
-
V
R
A
A
------------------
E
L
S
L
E
D
F
L
K
Q
M
Q
N
L
K
R
L
G
P
F
S
E
I
L
G
L
L
P
G
-
V
P
Q
G
L
-------
K
--
V
D
E
K
A
I
K
R
L
E
A
I
V
L
S
M
T
P
E
E
R
K
D
P
R
I
L
N
G
S
R
R
K
R
I
A
K
G
S
G
T
S
V
Q
E
V
N
R
F
I
K
A
F
E
E
M
K
A
L
M
K
S
L
E
K
----------------------
24
PsiBlast_CBE
76.46
43%
-81
- C7 -
2FFH
7
SRP54_THEAQ
B:
[1-418]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
A
S
L
A
E
K
-
V
R
A
A
------------
E
L
------
S
L
E
D
F
L
K
Q
M
Q
N
L
K
R
L
G
P
F
S
E
I
L
G
L
L
P
----------
G
V
P
Q
G
LK
V
D
E
K
A
I
K
R
L
E
A
I
V
L
S
M
T
P
E
E
R
K
D
P
R
I
L
N
G
S
R
R
K
R
I
A
K
G
S
G
T
S
V
Q
E
V
N
R
F
I
K
A
F
E
E
M
K
A
L
M
K
S
L
E
K
----------------------
70
HHSearch
76.41
35%
-84
- C7 -
3DM5
10
SRP54_PYRFU
A:
[2-434]
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
-----------
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
-
E
E
K
P
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
A
-------
K
-
P
-
I
E
--
I
------
K
---
E
K
--
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
-
R
G
Y
K
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
G
N
P
Q
E
K
D
-
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
Q
I
S
N
------
V
------
I
------
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
-
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
-
F
K
E
L
E
K
E
V
E
I
K
E
E
D
I
E
R
F
L
R
G
-
K
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
----------------------
I
S
--
I
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
N
K
R
Q
L
-------------------
25
PsiBlast_CBE
76.24
35%
-86
- C7 -
3DM5
9
SRP54_PYRFU
B:
[2-434]
V
L
D
N
L
G
K
A
L
A
N
T
L
K
K
I
A
R
A
-----------
S
S
V
D
E
A
L
I
K
E
L
V
R
D
I
Q
R
A
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
R
R
A
L
E
E
K
P
-
P
A
G
I
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
A
-------
K
-
P
-
I
E
--
I
K
---------
E
K
--
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
R
G
Y
K
-
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
R
Y
H
I
E
V
F
G
N
P
Q
E
K
D
-
A
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
-
M
K
Q
I
S
N
------
V
------
I
------
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
-
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
D
I
Q
G
L
L
E
K
F
K
E
L
E
K
E
V
E
I
-
K
E
E
D
I
E
R
F
L
R
G
K
-
F
T
L
K
D
M
Y
A
Q
L
E
A
M
R
K
M
G
P
-----------------------
S
--
I
G
E
E
R
L
K
K
F
K
V
I
M
D
S
M
T
E
E
E
L
L
N
P
E
I
I
N
Y
S
R
I
K
R
I
A
R
G
S
G
T
S
T
K
D
V
K
E
L
L
D
Q
Y
R
Q
M
K
K
L
F
K
S
M
N
-
K
R
Q
L
------------------
3
PsiBlast_PDB
76.18
43%
-78
- C7 -
2FFH
7
SRP54_THEAQ
A:
[1-418]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
A
S
L
A
E
K
-
V
R
A
A
------------
E
L
------
S
L
E
D
F
L
K
Q
M
Q
N
L
K
R
L
G
P
F
S
E
I
L
G
L
L
P
----------
G
V
P
Q
G
LK
V
D
E
K
A
I
K
R
L
E
A
I
V
L
S
M
T
P
E
E
R
K
D
P
R
I
L
N
G
S
R
R
K
R
I
A
K
G
S
G
T
S
V
Q
E
V
N
R
F
I
K
A
F
E
E
M
K
A
L
M
K
S
L
E
K
----------------------
23
PsiBlast_CBE
75.87
43%
-77
- C7 -
2FFH
9
SRP54_THEAQ
C:
[1-418]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
A
S
L
A
E
K
-
V
R
A
A
------------
E
L
------
S
L
E
D
F
L
K
Q
M
Q
N
L
K
R
L
G
P
F
S
E
I
L
G
L
L
P
----------
G
V
P
Q
G
LK
V
D
E
K
A
I
K
R
L
E
A
I
V
L
S
M
T
P
E
E
R
K
D
P
R
I
L
N
G
S
R
R
K
R
I
A
K
G
S
G
T
S
V
Q
E
V
N
R
F
I
K
A
F
E
E
M
K
A
L
M
K
S
L
E
K
----------------------
6
PsiBlast_PDB
75.57
36%
-82
- C7 -
3NDB
1
SRP54_METJA
B:
[1-437]
-
M
D
K
L
G
E
N
L
N
K
A
L
N
K
L
K
A
A
-----------
A
F
V
D
K
K
L
I
K
E
V
I
K
D
I
Q
R
A
L
I
Q
A
D
V
N
V
K
L
V
L
K
M
S
K
E
I
E
R
R
A
L
E
E
K
T
-
P
K
G
L
S
K
K
E
H
I
I
K
I
V
Y
E
E
L
V
K
L
L
G
E
E
A
-------
K
-
K
-
L
E
--
L
N
-----
P
---
K
K
--
Q
N
V
I
L
L
V
G
I
Q
G
S
G
K
T
T
T
A
A
K
L
A
R
Y
I
Q
K
R
G
L
K
P
A
L
-
I
A
A
D
T
Y
R
P
A
A
Y
E
Q
L
K
Q
L
A
E
K
I
H
V
P
I
Y
G
D
E
T
R
T
K
S
P
V
D
I
V
K
E
G
M
E
--
K
F
K
K
A
D
V
L
I
I
D
T
A
G
R
H
K
E
E
K
G
L
L
E
E
M
K
Q
I
K
E
------
I
------
T
------
N
------
P
D
E
I
I
L
V
I
D
G
T
I
G
Q
Q
A
G
I
Q
A
K
A
F
K
E
A
V
G
E
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
E
T
K
A
P
I
K
F
I
G
I
G
E
G
I
D
D
L
E
P
F
D
P
K
K
F
I
S
R
L
L
G
M
G
D
L
E
S
L
L
E
K
-
A
E
D
M
V
D
-
E
K
-
T
E
E
S
I
D
A
I
M
R
G
K
-
F
T
L
N
E
L
M
T
Q
L
E
A
I
E
N
M
-----------------------
L
T
E
--
A
K
I
K
K
Y
K
---
V
I
I
S
S
M
T
K
E
E
R
E
N
P
K
I
I
K
A
S
R
I
R
R
I
A
R
G
S
G
T
T
E
N
D
V
R
E
V
L
R
Y
Y
E
T
T
K
N
A
I
D
K
L
------------------------
27
PsiBlast_CBE
73.64
46%
-100
- C7 -
2J46
5
SRP54_THEAQ
B:
[1-297]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
72.51
45%
-93
- C7 -
2CNW
5
SRP54_THEAQ
B:
[4-293]
---
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
72.47
45%
-93
- C7 -
2J7P
11
SRP54_THEAQ
A:
[3-294]
--
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
72.02
46%
-97
- C7 -
2C03
10
SRP54_THEAQ
B:
[1-297]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
71.96
46%
-89
- C7 -
1O87
7
SRP54_THEAQ
B:
[1-295]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
71.86
45%
-94
- C7 -
1JPN
4
SRP54_THEAQ
A:
[1-296]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
71.85
46%
-97
- C7 -
2C04
2
SRP54_THEAQ
B:
[1-296]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
71.56
45%
-94
- C7 -
1JPN
4
SRP54_THEAQ
B:
[1-295]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
71.46
45%
-92
- C7 -
1JPJ
1
SRP54_THEAQ
A:
[1-294]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
71.44
45%
-95
- C7 -
2J7P
8
SRP54_THEAQ
B:
[4-294]
---
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
71.38
45%
-92
- C7 -
1OKK
17
SRP54_THEAQ
A:
[4-293]
---
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
71.27
45%
-95
- C7 -
3NG1
6
SRP54_THEAQ
A:
[1-294]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
71.27
46%
-95
- C7 -
1O87
7
SRP54_THEAQ
A:
[1-295]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
70.97
45%
-91
- C7 -
1NG1
13
SRP54_THEAQ
A:
[1-294]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
70.67
45%
-95
- C7 -
3NG1
7
SRP54_THEAQ
B:
[1-294]
M
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
69.27
45%
-89
- C7 -
2NG1
4
SRP54_THEAQ
A:
[1-293]
-
F
Q
Q
L
S
A
R
L
Q
E
A
I
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
67.83
46%
-89
- C7 -
1RJ9
3
SRP54_THEAQ
B:
[14-295]
-------------
G
R
L
R
G
R
-----------
G
R
I
T
E
E
D
L
K
A
T
L
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
E
E
A
L
G
K
Q
V
-
L
E
S
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
--
G
-------
E
-
A
-
R
L
--
P
V
-----
L
---
K
D
--
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
P
L
L
V
-
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
K
V
G
V
P
V
L
E
V
M
D
G
E
S
-
P
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
------
V
------
L
------
G
------
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
-
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
Y
P
E
R
L
A
G
R
I
L
G
M
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
79
HHSearch
67.49
36%
-100
- C7 -
3E70
3
?
C:
[7-324]
M
F
G
K
L
R
E
K
L
K
S
F
V
K
R
V
E
E
E
VEKEEEEVILT
V
E
I
K
E
K
D
V
D
K
A
L
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
-
G
K
K
V
R
I
G
---
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
-------
R
I
D
L
I
E
EI
R
K
-----
A
---
E
K
--
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
-
H
G
F
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
V
I
K
H
S
Y
G
A
D
-
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
------
V
------
T
------
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
-
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
81
HHSearch
67.48
35%
-96
- C7 -
2YHS
5
FTSY_ECOLI
A:
[225-495]
--------------------------------------
D
D
L
F
E
E
L
E
E
Q
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
-
R
K
----
Q
L
R
D
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
-------
E
-
P
-
L
N
--
V
E
-----
G
---
K
A
--
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
-
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
A
Q
H
T
G
A
D
-
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
------
V
M
K
K
L
DV
E
------
A
------
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
-
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
67.10
36%
-93
- C7 -
4C7O
5
FTSY_ECOLI
D:
[19-267]
---------------------------------------------------
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
-----
R
K
Q
L
R
D
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
-------
E
-
P
-
L
N
--
V
E
-----
G
---
K
A
--
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
A
Q
H
T
G
A
D
-
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
------
V
------
M
------
K
K
L
DVEA
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
-
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
PsiBlast_CBE
66.04
36%
-89
- C7 -
4C7O
4
FTSY_ECOLI
B:
[19-267]
---------------------------------------------------
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
-----
R
K
Q
L
R
D
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
-------
E
-
P
-
L
N
--
V
E
-----
G
---
K
A
--
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
A
Q
H
T
G
A
D
-
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
------
V
------
M
------
K
K
L
DVEA
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
-
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
PsiBlast_CBE
64.93
37%
-100
- C7 -
3E70
3
?
C:
[46-324]
-------------------------------
E
I
K
E
K
D
V
D
K
A
L
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
K
V
-
R
I
G
---
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
-------
R
I
D
-
L
I
--
E
E
-----
I
RKA
E
K
--
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
H
G
F
-
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
V
I
K
H
S
Y
G
A
D
-
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
------
V
------
T
------
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
-
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
64.88
35%
-98
- C7 -
2YHS
5
FTSY_ECOLI
A:
[238-495]
---------------------------------------------------
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
E
G
A
S
-----
R
K
Q
L
R
D
A
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
-------
E
-
P
-
L
N
--
V
E
-----
G
---
K
A
--
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
-
E
Q
Q
G
K
S
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
R
N
N
I
P
V
I
A
Q
H
T
G
A
D
-
S
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
------
V
------
M
------
K
K
L
DVEA
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
-
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
64.84
37%
-98
- C7 -
3DMD
4
?
B:
[46-324]
-------------------------------
E
I
K
E
K
D
V
D
K
A
L
D
E
L
E
I
D
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
Q
K
L
V
G
K
K
V
-
R
I
G
T
D
K
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
-------
R
I
D
-
L
I
--
E
E
-----
I
R
K
A
E
K
--
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
H
G
F
-
S
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
I
G
V
K
V
I
K
H
S
Y
G
A
D
-
P
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
------
V
------
T
------
K
------
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
-
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
88
HHSearch
64.09
31%
-103
- C7 -
1RJ9
3
FTSY_THEAQ
A:
[27-303]
------------------------------------
N
L
E
E
V
L
E
E
L
E
M
A
L
L
A
A
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
A
S
G
R
-
K
-----------
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
E
R
R
A
T
L
R
K
L
-
G
-
F
N
--
P
Q
KPKPV
E
---
P
K
--
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
-
L
G
K
K
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
S
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
------
E
------
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
61.77
42%
-100
- C7 -
1VMA
1
?
B:
[85-304]
----------------------------------------------------------------------------------------------
E
I
I
L
E
I
L
N
-------
F
-
D
-
T
K
--
L
N
-----
V
---
P
P
EP
P
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
V
D
-
E
G
K
S
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
R
V
G
A
T
V
I
S
H
S
E
G
A
D
-
P
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
------
V
------
V
------
K
KKIPDA
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
-
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
56.41
37%
-85
- C7 -
2J7P
5
FTSY_THEAQ
D:
[94-281]
-------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
------
A
------
I
A
K
A
DPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
64
PsiBlast_CBE
56.19
36%
-84
- C7 -
1RJ9
3
FTSY_THEAQ
A:
[115-302]
-------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
S
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
------
A
------
I
A
K
A
DPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
PsiBlast_CBE
55.86
37%
-82
- C7 -
1OKK
8
FTSY_THEAQ
D:
[114-301]
-------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
------
A
------
I
AKADPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
55.58
37%
-86
- C7 -
2J7P
9
FTSY_THEAQ
E:
[94-281]
-------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
------
A
------
I
AKADPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
PsiBlast_CBE
54.08
37%
-89
- C7 -
2Q9C
7
FTSY_THEAQ
A:
[115-302]
-------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
------
A
------
I
A
K
A
DPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
PsiBlast_CBE
53.05
37%
-90
- C7 -
2IYL
3
FTSY_THEAQ
D:
[95-282]
-------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
------
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
------
A
------
I
AKADPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
--
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
52.48
37%
-89
- C7 -
2Q9B
11
FTSY_THEAQ
A:
[115-302]
-------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
R
L
S
I
P
V
I
Q
G
P
E
G
T
D
-
P
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
------
A
------
I
A
K
A
DPE
E
------
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
-
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------