Atome 3 Filter

@TOME V3
(Feb 2022)

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Sequence color : MutatedHelixStrandConserved

Query sequence : R7Y0S1_9ACTN: (2019-02-02 )
MHTHDVTVMGDVVRKRYVSWDDREPEREWAGLVHLSRESPGLAPTPVAREVEDGRPVVVMSLVPGEPLTSALSAAQSKAFAEVLRRLFAVPVPEDLAERANGPQVMRDHVREWLSEDYDLTQCQDQALVRTAKDRAVAWLAVVQLPDLVDRVVAQGDGNLDNVLWDGEVCRLIDWEEYGASDLTYEIADVVEHASSRLTRSLDVDALLADLDLDPTQRERLAVHRLLLACFWLMMLLPGNGGFKRNPAGSTEDQARHVLALLDQS

Atome Classification :

	(20 SA)										-------------------------------------------------...-..----....10........20-----.--....-------....30.-.......40.-.-......-----50---.-.------.----...---------...60....-.-.-------------..70.----.--------.......--80.....-...90--.---....--.---...--100--------------.-.......----110....---...120-..----..----..---..------.130...-....140--..--......150-........160...-..----.-.170.....----..180...-....190.---....---------------..200.......210------.----.-.--.------------.-------...220..----.....230.......240.......250....-----...260...---------------
		(Atome)	(Ident)	(Tito)	(Num)	(QMean)		(Ligand)	(Uniprot)		-------------------------------------------------MHT-HD----VTVMGDVVRKRYVSW------D--DREP-------EREWAGL-VHLSRESPGL-A-PTPVAR-----E----V-E------D----GRP---------VVVMSLVPG-E-P-------------LTS-A----L--------SAAQSKA--FAEVLRR-LFAV---P---VPED--L---AER--AN---------------G-PQVMRDH----VREWLSE---DYDL---TQ----CQ----DQ---AL------VRTAKDR-AVAWLA---VV--QLPDLVDR--VVAQGDGNLDNVLW-DG----E-VCRLIDWEE----YGASDLTY-EIADVVEH---ASSR---------------LTRSLDVDALLADL-------D----L-D--P------------T-------QRERLAVH----RLLLACFWLMMLLPGNGGFKRNPAGSTEDQAR-----HVLALLDQS---------------
58	SP3	80.32	21%	7	- C4 -	-	1ND4		KKA2_KLEPN	A:[10-264]	-----------------------------GSPAAWVERLFGYDWAQQTIGCS-DAAVFRLSAQGRPV--LFVKT------D--LSGALNEL---QDEAARL-SWLATT--GV-PCAAVLDV-----V----T-E------A----GRD---------WLLLGEVPG-Q-D-------------LLS-SHL--A--------PAEKVSI--MADAMRR-LHTL---DPATCPFDHQA---KHR---------------------IERARTR----MEAGLVD---QDDL---------------DE---EH------QGLAPAE-LFARLK---A---RMPDGEDL--VVTHGDACLPNIMVENG----R-FSGFIDCGR----LGVADRYQ-DIALATRD---IAEE---------------LGGEW-ADRFLVLY-------G----I-A--A------------P-------DSQRIAFY----RLLDEFF------------------------------------------------------
31	Fugue	78.00	20%	22	- C4 -	-	1J7L		KKA3_ENTFL	A:[2-264]	-------------------------AKMRISPELKKLIEKYRCVKDTEGMSP-AK----VYKLVGENENLYLKM------T--DSRYKGTTYDVEREKDMM-LWLEGKLP---V-PKVLHF-----E----R-H------D----GWS---------NLLMSEADG-V-L-------------CSE-E----YEDEQS---PEKIIEL--YAECIRL-FHSI---D---ISD-------CPY--TN---------------S-LDSRLAE----LDYLLNN---DLAD---VD----CE----NW---EE------DTPFKDP-RELYDF---LK--TEKPEEEL--VFSHGDLGDSNIFVKDG----K-VSGFIDLGR----SGRADKWY-DIAFCVRS---IRED---------------IGEEQYVELFFDLL-------G----I-K--P------------D--------WEKIKYY----ILLDELF------------------------------------------------------
32	Fugue	74.59	13%	13	- C4 -	-	3JR1		?	A:[14-309]	-----------------NLYFQGMWKSISQVLAEQFGAYYFIKHKEKLYSGEMNE----IWLINDEVQTVFVKI------N--ERSYRSMF---RAEADQL-ALLAKTNSIN-V-PLVYGI-----G----N-S------Q----GHS---------FLLLEALNK-S-K-------------NKQ-S----------------SFTI--FAEKIAQ-LHQI---Q---GPDK--YGLDFDT--WL---------------G-PIYQPNDWQTSWAKFFSENRIGWQL---QI----CK----EK---GL------IFGNIDL-IVQIVA---DT--LSKHNPKP--SILHGNLWIENCIQ-VD----D-KIFVCNP-----------ACY-WGDRECDI---AFSS---------------LFEPFP-TNFYQRY-------N----E-I--Y------------P-------LEEGYLER----KLIYQLYYLLNFSYRYYN----KKQSYVSLTQ-----KLINQILHK---------------
44	HHSearch	69.62	18%	-24	- C4 -	-	3TDW		?	A:[37-279]	------------------------------------------------------------LVNGDWVFRFPKSQ------QG-ADEL-------NKEIQLL-PLLVGCVKVN-I-PQYVYI-----G----KRS------D----GNP---------FVGYRKVQG-Q-I-------------LGE-DGMAVLPDDA----KDRLALQ--LAEFMNE-LSAF---P---VET---A---ISA--GV---------------P-VTNLKNK----ILLLSEA---VEDQ---VF----PL----LD---ES------LRDYLTLRFQSYMT----H--PVYTRYTP--RLIHGDLSPDHFLT-NLNSRQTPLTGIIDFGD----AAISDPDY-DYVYLLED---CGE--------------------L-FTRQVMAY-------R----GEVDLD------------T-------HIRKVSLF----VTFDQVSYLLEGLR-----------------------------------------------
50	HHSearch	69.01	19%	-1	* C4 *	-	4GKI		?	C:[51-270]	---------------------------------------------------------------PELFLKHGKGS------V--ANDV-------TDEMVRL-NWLTA--FMP-L-PTIKHF-----I----R-T------P----DDA---------WLLTTAIPG-K-T-------------AFQ-V----LEEYPDS--GENIVDA--LAVFLRR-LHSI---P---VCN---C---PFN--SD---------------R-VFRLAQA----QSRMNNG---LVDA---SD----F-----DD---ER------NGWPVEQ-VWKEMH---KL---LPFSPDS--VVTHGDFSLDNLIF-DEG---K-LIGCIDVGR----VGIADRYQ-DLAILWNC---LGEF-----------------SPSLQKRLFQKY-------G----I-D--N------------P-------DMNKLQFH----LMLDE--------------------------------------------------------
57	SP3	68.86	16%	33	- C4 -	-	1J7L		KKA3_ENTFL	A:[2-264]	-----------------AKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVG-EN----ENLYLKMTDSRYKG-------T--TYDV-------EREKDMM-LWLEGKLP---V-PKVLHF-----E----R-H------D----GWS---------NLLMSEADG-V-L-------------CSE-E----YEDEQS---PEKIIEL--YAECIRL-FHSI---D---ISD-------CPY--TN---------------S-LDSRLAE----LDYLLNN---DLAD---VD----CE----NW---EE------DTPFKDP-RELYDF---LK--TEKPEEEL--VFSHGDLGDSNIFVKDG----K-VSGFIDLGR----SGRADKWY-DIAFCVRS---IRED---------------IGEEQYVELFFDLL-------G----I-K--P------------D--------WEKIKYY----ILLDELF------------------------------------------------------
51	HHSearch	67.03	19%	-2	- C4 -	-	4GKH		?	A:[51-270]	---------------------------------------------------------------PELFLKHGKGS------V--ANDV-------TDEMVRL-NWLTA--FMP-L-PTIKHF-----I----R-T------P----DDA---------WLLTTAIPG-K-T-------------AFQ-V----LEEYPDS--GENIVDA--LAVFLRR-LHSI---P---VCN---C---PFN--SD---------------R-VFRLAQA----QSRMNNG---LVDA---SD----F-----DD---ER------NGWPVEQ-VWKEMH---KL---LPFSPDS--VVTHGDFSLDNLIF-DEG---K-LIGCIDVGR----VGIADRYQ-DLAILWNC---LGEF-----------------SPSLQKRLFQKY-------G----I-D--N------------P-------DMNKLQFH----LMLDE--------------------------------------------------------
55	HHSearch	66.83	16%	-21	- C4 -	-	3C5I		?	A:[67-334]	---------------------------------------------------------------TRVLFRIYGKH------VDELYNT-------ISEFEVY-KTMSK-YKI--A-PQLLNT-----F-------------------NG---------GRIEEWLYG-D-P-------------LRI-DDL--K--------NPTILIG--IANVLGK-FHTL---S---RKRH--L---PEH--WD---------------R-TPCIFKM----MEKWKNQ---LFKY---KN----IEKYC-DI---HK------YIKESDK-FIKFMK---VYSKSDNLANTI--VFCHNDLQENNIIN-TN------CLRLIDFEY----SGFNFLAT-DIANFFIE---TSIDYSVSSYPFFEIDKKKYISYENRKLFITAY-------L----SNY--L------------PTPKLIDEILEAVEVQ----ALGAHLLWGFWSIIRG---------------------------------------------
54	HHSearch	66.03	16%	-2	- C4 -	-	3C5I		?	D:[67-330]	---------------------------------------------------------------TRVLFRIYGKH------VDELYNT-------ISEFEVY-KTMSK-YKI--A-PQLLNT-----F-------------------NG---------GRIEEWLYG-D-P-------------LRI-DDL--K--------NPTILIG--IANVLGK-FHTL---S---RKRH--L---PEH--WD---------------R-TPCIFKM----MEKWKNQ---LFKY---KN----IEKYNCDI---HK------YIKESDK-FIKFMK---VYSKSDNLANTI--VFCHNDLQENNIIN-TN----K-CLRLIDFEY----SGFNFLAT-DIANFFIE---TSIDYSVSSYPFFEIDKKKYISYENRKLFITAY-------L----SNY--LDKVV--------PTPKLIDEILEAVEVQ----ALGAHLLWGFWSIIRG---------------------------------------------
28	Fugue	65.77	15%	27	- C4 -	-	2PPQ	-	KHSE_AGRFC	A:[5-320]	-----------------------TDITEDELRNFLTQYDVGSLTSYKGIAEN-SN----FLLHTTKDPLILTLY------E--KKND-------LPFFLGLMQHLAAKGLSC-P-LPLPRKDGELLG----E-L------S----GRP---------AALISFLEGMW-L-------------RKP---------------EAKHCRE--VGKALAAMHLAS---E---GFEI--K---RPN--AL---------------S-VDGWKVL----WDKSEER---ADEV---EK----GL----RE---EI------RPEIDYL-AAHW-----------PKDLPA--GVIHADLFQDNVFF-LGD---E-LSGLIDFYF----ACNDLLAY-DVSICLNAWCFEKDG---------------AYNVTKGKALLEGY-------QSVRPL-S--E------------A-------ELEALPLL----SRGSALRFFLTRLYDWLTTPAGALVVKKDPLE-----YLRKLRFHRTIANVAEYGLA----
25	Fugue	65.45	14%	5	- C4 -	-	3ATS		Y3168_MYCTU	A:[1-357]	TLPAVISRWLSSVLPGGAAPEVTVESGVDSTGMSSETIILTARWQQDGRSIQ-QK----LVARVAPAAEDVPVF------P--TYRL-------DHQFEVI-RLVGELT-DV-P-VPRVRW-----I----E-T------TGDVLGTP---------FFLMDYVEG-V-VPPDVMPYTFGDNWFAD-A----P--------AERQRQL--QDATVAA-LATLH--S---IPNA--Q---NTF--SF---------------L-TDTTLHR----HFNWVRS---WYDF---AV----EG----IG---RS--------PLLER-TFEWLQ---SH--WPDDAAAREPVLLWGDARVGNVLYRDF----Q-PVAVLDWEMVALGPRELDVAWMIFAHRVFQ---ELAG---------------LATLPGLPEVMRED-------D----V-R--A------------T-------YQALTGVELGDLHWFYVYSGVMWACVFMRTGARRVHFGEIEKPD-----DVESLFYHAGLMKHLLGEEH----
48	HHSearch	64.94	16%	-6	- C- -	-	3N4U	-	?	A:[40-283]	--------------------------------------------------------------NRDFIFKFPKHS------RG-STNL-------FNEVNIL-KRIHNKLPLP-I-PEVVFT-----G----M-PSET---Y----QMS---------FAGFTKIKG-V-P-------------LTP-L----LLNNLPKQSQNQAAKD--LARFLSE-LHSI---N---ISG---F---KSN--L------------------VLDFREK----INEDNKK---IK------K----LL----SR---EL------KGPQMKK-VDDFYRDILEN--EIYFKYYP--CLIHNDFSSDHILF-DTEKN-T-ICGIIDFGD----AAISDPDN-DFISLMED---DEE-----------------YGMEFVSKILNHY-------K----HKDI-P------------T-------VLEKYRMK----EKYWSFEKIIYGKEYG---------------------------------------------
41	HHSearch	63.93	14%	-21	- C4 -	-	1NW1	-	CKA2_CAEEL	A:[105-395]	--------------------------------------------------------------PNKVLLRVYFNP------ET-ESHL-------VAESVIF-TLLSE-RHLG---PKLYGI-----F-------------------SG---------GRLEEYIPS-R-P-------------LSC-HEI--S--------LAHMSTK--IAKRVAK-VHQL---E---VPI---W---KE---P-------------------DYLCEA----LQRWLKQ---LTGT---VDAEHRFD----LP---EECGVSSVNCLDLAR-ELEFLR---AH--ISLSKSPV--TFCHNDLQEGNILL-PK------RLVLIDFEY----ASYNYRAF-DFANHFIE---WTIDYDIDEAPFYKIQTENFPENDQMLEFFLNY-------L----REQ--GNTRENELYKKSED-------LVQETLPF----VPVSHFFWGVWGLLQV---------------------------------------------
46	HHSearch	63.83	19%	9	- C4 -	-	5IGH	-	?	A:[46-283]	--------------------------------------------------------------GRRWVLRIPRRA------EV-SAKV-------EPEARVL-AMLKNRLPFA-V-PDWRVA-----N----A-EL-----VAYPMLED---------STAMVIQPG-S-S-------------TPD-WVVPQD--------SEVFAES--FATALAA-LHAV---P---ISA---A---VDA--GM---------------L-IRTPTQA----RQKVADD---VD------R----VR----REF--VV------NDKRLHR-WQRWLD---DD--S-SWPDFS--VVVHGDLYVGHVLI-DNTE--R-VSGMIDWSE----ARVDDPAI-DMAAHLMV---FGE--------------------EGLAKLLLTY-------E----AAG--GRVWP--------R-------LAHHIAER----LAFGAVTYALFALD-----------------------------------------------
42	HHSearch	63.83	14%	-21	- C4 -	-	1NW1	-	CKA2_CAEEL	B:[105-395]	--------------------------------------------------------------PNKVLLRVYFNP------ET-ESHL-------VAESVIF-TLLSE-RHLG---PKLYGI-----F-------------------SG---------GRLEEYIPS-R-P-------------LSC-HEI--S--------LAHMSTK--IAKRVAK-VHQL---E---VPI---W---KE---P-------------------DYLCEA----LQRWLKQ---LTGT---VDAEHRFD----LP---EECGVSSVNCLDLAR-ELEFLR---AH--ISLSKSPV--TFCHNDLQEGNILL-PK------RLVLIDFEY----ASYNYRAF-DFANHFIE---WTIDYDIDEAPFYKIQTENFPENDQMLEFFLNY-------L----REQ--GNTRENELYKKSED-------LVQETLPF----VPVSHFFWGVWGLLQV---------------------------------------------
40	HHSearch	63.79	14%	-17	- C4 -	-	3DXQ	-	?	B:[37-261]	---------------------------------------------------------------GDLCLRIP--------------NR-------ANEAVAA-REAAK-AGVS---PEVLHV-----D----P-------------ATG---------VMVTRYIAG-AQT-------------MSP-EK---FKT------RPGSPAR--AGEAFRK-LHGS---G---AVFP--F---RF------------------------ELFAM----IDDYLKV---LSTK---NV----T-----LP---AG------YHDVVRE-AGGVRS----A--LAAHPLPL--AACHCDPLCENFLD-TG----E-RMWIVDWEY----SGMNDPLW-DLGDLSVE---GKFN------------------ANQDEELMRAY-------F----GGEARP------------A-------ERGRVVIY----KAMCDLLWTLWGLIQL---------------------------------------------
53	HHSearch	63.46	15%	-8	- C4 -	-	3I1A		?	B:[46-291]	--------------------------------------------------------------SKSYFIKLKYGY------H-----D-------EINLSII-RLLHD-SGIKEI-IFPIHT-----L----E-AKLFQQLK----HFK---------IIAYPFIHA-P-N-------------GFTQN----L--------TGKQWKQ--LGKVLRQ-IHET---S---VPIS--I---QQQLRKE---------------IYSPKWREI----VRSFYNQ---IEFDNSDDK----LTAA--FKSFFNQ------NSAAIHR-LVDTSEKLSKK--IQPDLDKY--VLCHSDIHAGNVLV-GNE---E-SIYIIDWDE----PMLAPKER-DLMFIGGG---VGNV---------------WNKPHEIQYFYEGY-------G----EIN--V--------------------DKTILSYY----RHERIVEDIAV--------------------------------------------------
26	Fugue	63.20	15%	28	- C4 -	-	3I1A		?	A:[3-330]	-------------------KQPIQAQQLIELLKVHYGIDIHTAQFIQGGADT-NA----FAYQADSESKSYFIK------L--KYGY-------HDEINLS-IIRLLHDSGI-K-EIIFPI-----H----T-L------E----AKLFQQLKHFKIIAYPFIHAP-N-G-------------FTQ-N----L--------TGKQWKQ--LGKVLRQ-IHET---S---VPIS--I---QQQ--LRKEIYSPKWREIVRSFY-NQIEFDN----SDDKLTA---AFKS---FF----NQ----NS---AA------IHRLVDT-SEKLSK---KI--Q-PDLDKY--VLCHSDIHAGNVLVGNE----E-SIYIIDWDE----PMLAPKER-DLMFIGGG---VGNV---------------WNKPHEIQYFYEGYGEI----N----V-D--K------------T-------ILSYYRHE----RIVEDIAVYGQDLLSRNQNNQSRLESFKYFKEMFDPNNVVEIAFATE--------------
6	PsiBlast_PDB	62.40	26%	27	- C4 -	-	1ND4		KKA2_KLEPN	A:[85-260]	-----------------------------------------------------------------------------------------------------------------------------------T-E------A----GRD---------WLLLGEVPG-Q-D-------------LLS-S----H--------LAPAEKVSIMADAMRR-LHTLDPAT---CPFD------HQA--KH---------------R-IERARTR----MEAGLVD---QDDL---DE-----E----HQ---GL---------APAE-LFARLK---A---RMPDGEDL--VVTHGDACLPNIMVENG----R-FSGFIDCGR----LGVADRYQ-DIALATRD---IAEE---------------LGGEW-ADRFLVLY-------G----I-A--A------------P-------DSQRIAFY----RLL----------------------------------------------------------
23	Fugue	61.96	14%	14	- C4 -	-	1ZYL	-	SRKA_ECOLI	A:[4-328]	----------------SAFTFQTLHPDTIMDALFEHGIRVDSGLTPLNSYEN-RV----YQFQDEDRRRFVVKFYRPERWT--ADQI-------LEEHQFA-LQLVNDEVPV-A-APVAFN-----GQTLLN-H------Q----GFY---------FAVFPSVGG-R-Q-------------FEA-D-------------NIDQMEA--VGRYLGR-MHQT---G---RKQL--F---IHR--PTI--------------G-LNEYLIE----PRKLFED---ATLI---PS----GL----KA---AF------LKATDEL-IAAVTA---H----WREDFTV--LRLHGDCHAGNILW-RD----G--PMFVDLDD----ARNGPAVQ-DLWMLL-----NGDK---------------AEQRMQLETIIEAYEEFSEFDT----A-E--I------------G-------LIEPLRAM----RLVYYLAWLMRRWADPAFPKNFPWLTGEDYWL-----RQTATFIEQAKVLQEPPLQLTPMY