Atome 2 Filter

@TOME V2.3
(Mar 2018)

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3D Common Core:

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Modeller Result :

Complexes Modeling

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Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]

Sequence color : MutatedHelixStrandConserved

Query sequence : CRK1: (2018-07-12 )
MTSRYERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRHENIVKLLDVCHSEHRLTIVFEYLDLDLKKYLDRENGNLDAATVQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKELKLGDFGLGRSFAIPVRKFTNEVVTLWYRPPDVLLGSMQYGPPVDVWSVGCIFSEMATGTPLFAGKNDADQLMRIFRFLGTPNNRVWPSMNQYPNSNNMLSQPEFLQNFEPEWSNVLGSVPGYEKLGCAGVDLLEKLLRYEPSERITAADALNHPYFSLQF

Atome Classification :

	(27 SA)										.........10........20........30........40........50........60........70.------.......80........90...--..-...100.......110.......120.......130...--....140.......150.....----..160.......170.......180.......190.....-..200.......-.-210.......220.......230.......240.......250.-.......260...-....270.......280.......290.......300
		(Atome)	(Ident)	(Tito)	(Num)	(QMean)		(Ligand)	(Uniprot)		MTSRYERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRHENIVKLLDVCH------SEHRLTIVFEYLDLDLKKYLDR--EN-GNLDAATVQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLI--SREKELKLGDFGLGRSFAIPVR----KFTNEVVTLWYRPPDVLLGSMQYGPPVDVWSVGCIFSEMA-TGT-PLFAGKND-A-DQLMRIFRFLGTPNNRVWPSMNQYPNSNNMLSQPEFLQNFEP-E-WSNVLGSVPGYEK-LGCAGVDLLEKLLRYEPSERITAADALNHPYFSLQF
28	HHSearch	94.87	58%	-114	- C1 -	-	1V0B	-	CDC2H_PLAFK	A:[2-286]	--EKYHGLEKIGEGTYGVVYKAQNN-YGETFALKKIRLEKEDEGIPSTTIREISILKELKHSNIVKLYDVIH------TKKRLVLVFEHLDQDLKKLLDV--CE-GGLESVTAKSFLLQLLNGIAYCHDRRVLHRDLKPQNLLI--NREGELKIADFGLARAFGIPVR----KYTHEVVTLWYRAPDVLMGSKKYSTTIDIWSVGCIFAEMV-NGA-PLFPGVSE-A-DQLMRIFRILGTPNSKNWPNVTELPKYDPNFTVYEP-----L-P-WES------FLKG-LDESGIDLLSKMLKLDPNQRITAKQALEHAYFKE--
3	PsiBlast_PDB	93.99	57%	-104	- C1 -	-	1V0P		CDC2H_PLAFK	A:[3-285]	---KYHGLEKIGEGTYGVVYKAQN-NYGETFALKKIRLEKEDEGIPSTTIREISILKELKHSNIVKLYDVIH------TKKRLVLVFEHLDQDLKKLLDV--CE-GGLESVTAKSFLLQLLNGIAYCHDRRVLHRDLKPQNLLI--NREGELKIADFGLARAFG-------------IVTLWYRAPDVLMGSKKYSTTIDIWSVGCIFAEMV-NGT-PLFPGVSE-A-DQLMRIFRILGTPNSKNWPNVTELPKYD-----PNF-TVYEPLP-WESFL------KG-LDESGIDLLSKMLKLDPNQRITAKQALEHAYFK---
4	PsiBlast_PDB	93.41	57%	-96	- C1 -	-	1V0B	-	CDC2H_PLAFK	A:[3-285]	---KYHGLEKIGEGTYGVVYKAQN-NYGETFALKKIRLEKEDEGIPSTTIREISILKELKHSNIVKLYDVIH------TKKRLVLVFEHLDQDLKKLLDV--CE-GGLESVTAKSFLLQLLNGIAYCHDRRVLHRDLKPQNLLI--NREGELKIADFGLARAFGIPVR----KYTHEVVTLWYRAPDVLMGSKKYSTTIDIWSVGCIFAEMV-NGA-PLFPGVSE-A-DQLMRIFRILGTPNSKNWPNVTELPKYD-----PNF-TVYEPLP-WESFL------KG-LDESGIDLLSKMLKLDPNQRITAKQALEHAYFK---
6	PsiBlast_PDB	87.83	56%	-98	- C1 -	-	3NIZ		?	A:[19-304]	LMEKYQKLEKVGEGTYGVVYKAKD-SQGRIVALKRIR------GIPSTAIREISLLKELHHPNIVSLIDVIH------SERCLTLVFEFMEKDLKKVLDE--NK-TGLQDSQIKIYLYQLLRGVAHCHQHRILHRDLKPQNLLI--NSDGALKLADFGLARAFGIPVR-------HEVVTLWYRAPDVLMGSKKYSTSVDIWSIGCIFAEMI-TGK-PLFPGVTD-D-DQLPKIFSILGTPNPREWPQVQELP-----LWKQRTFQVFEK-KPWSSI---IPGFCQ----EGIDLLSNMLCFDPNKRISARDAMNHPYF----
1	PsiBlast_PDB	87.47	57%	-91	- C1 -	-	1V0O		CDC2H_PLAFK	A:[3-285]	---KYHGLEKIGEGTYGVVYKAQN-NYGETFALKKIRL--------STTIREISILKELKHSNIVKLYDVIH------TKKRLVLVFEHLDQDLKKLLDV--CE-GGLESVTAKSFLLQLLNGIAYCHDRRVLHRDLKPQNLLI--NREGELKIADFGLARAFGIPVR----KYTHEVVTLWYRAPDVLMGSKKYSTTIDIWSVGCIFAEMV-NGT-PLFPGVSE-A-DQLMRIFRILGTPNSKNWPNVTELPKYD-----PNFTV-YEPLP-WESFL------KG-LDESGIDLLSKMLKLDPNQRITAKQALEHAYFK---
11	PsiBlast_PDB	84.40	55%	-80	- C1 -	-	1UNL		CDK5_HUMAN	A:[3-287]	---KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLH------SDKKLTLVFEFCDQDLKKYFDS--CN-GDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLI--NRNGELKLANFGLARAFGIPVR----CYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGR-PLFPGNDV-D-DQLKRIFRLLGTPTEEQWPSMTKLPDYK---PYPMY-----P-A-TTSLVNVVP---K-LNATGRDLLQNLLKCNPVQRISAEEALQHPYFS---
12	PsiBlast_PDB	84.21	55%	-80	- C1 -	-	3O0G	-	CDK5_HUMAN	A:[3-287]	---KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLH------SDKKLTLVFEFCDQDLKKYFDS--CN-GDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLI--NRNGELKLANFGLARAFGIPVR----CYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGR-PLFPGNDV-D-DQLKRIFRLLGTPTEEQWPSMTKLPDYK---PYPMY-----P-A-TTSLVNVVP---K-LNATGRDLLQNLLKCNPVQRISAEEALQHPYFS---
9	PsiBlast_PDB	83.83	55%	-84	- C1 -	-	1UNG		CDK5_HUMAN	A:[3-287]	---KYEKLEKI----YGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLH------SDKKLTLVFEFCDQDLKKYFDS--CN-GDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLI--NRNGELKLANFGLARAFGIPVR----CYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGR-PLFPGNDV-D-DQLKRIFRLLGTPTEEQWPSMTKLPDYK---PYPMY-----P-A-TTSLVNVVP---K-LNATGRDLLQNLLKCNPVQRISAEEALQHPYFS---
35	HHSearch	83.71	54%	-42	* C1 *	-	3QHW		CDK2_HUMAN	A:[4-291]	--ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIH------TENKLYLVFEFLHQDLKKFMDA--SALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI--NTEGAIKLADFGLARAFGVPVR----TYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-TRR-ALFPGDSE-I-DQLFRIFRTLGTPDEVVWPGVTSMPDYKP----------SFP-K-WARQDF-SKVVPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDV-
8	PsiBlast_PDB	83.33	55%	-89	- C1 -	-	1H4L	-	CDK5_HUMAN	A:[3-287]	---KYEKLEKI----YGTVFKAKNRETHEIVALKRVRLD----GVPSSALREICLLKELKHKNIVRLHDVLH------SDKKLTLVFEFCDQDLKKYFDS--CN-GDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLI--NRNGELKLADFGLARAFGIPVR----CYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELA-NAARPLFPGNDV-D-DQLKRIFRLLGTPTEEQWPSMTKLPDYK---PYPMY-----P-A-TTSLVNVVP---K-LNATGRDLLQNLLKCNPVQRISAEEALQHPYFS---
10	PsiBlast_PDB	82.99	55%	-89	- C1 -	-	1UNH	-	CDK5_HUMAN	A:[3-287]	---KYEKLEKI----YGTVFKAKNR--HEIVALKRVRLD----GVPSSALREICLLKELKHKNIVRLHDVLH------SDKKLTLVFEFCDQDLKKYFDS--CN-GDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLI--NRNGELKLANFGLARAFGIPVR----CYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGR-PLFPGNDV-D-DQLKRIFRLLGTPTEEQWPSMTKLPDYK---PYPMY-----P-A-TTSLVNVVP---K-LNATGRDLLQNLLKCNPVQRISAEEALQHPYFS---
29	HHSearch	82.70	56%	-81	- C1 -	-	1UNL		CDK5_HUMAN	A:[2-288]	--QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLH------SDKKLTLVFEFCDQDLKKYFDS--CN-GDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLI--NRNGELKLANFGLARAFGIPVR----CYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELA-NAG-RPLFPGND-VDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYPMY--------P-A-TTSL---VNVVPK-LNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD--
33	HHSearch	81.05	52%	-115	- C1 -	-	5G6V		CDK16_HUMAN	B:[2-288]	--ETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEG-APCTAIREVSLLKDLKHANIVTLHDIIH------TEKSLTLVFEYLDKDLKQYLDD--CG-NIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLI--NERGELKLADFGLARA----------------VTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMA-TGR-PLFPGSTV-E-EQLHFIFRILGTPTEETWPGILSNEE----FKTYNYPKYRAE-A-LLS------HAPR-LDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSL-
32	HHSearch	80.99	52%	-101	- C1 -	-	5G6V		CDK16_HUMAN	A:[2-288]	--ETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEG-APCTAIREVSLLKDLKHANIVTLHDIIH------TEKSLTLVFEYLDKDLKQYLDD--CG-NIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLI--NERGELKLADFGLARAK---------TYDNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMA-TGR-PLFPGSTV-E-EQLHFIFRILGTPTEETWPGILSNEE----FKTYNYPKYRAE-A-LLS------HAPR-LDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSL-
20	PsiBlast_PDB	80.90	53%	-49	- C1 -	-	1FIN		CDK2_HUMAN	A:[4-286]	----FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIH------TENKLYLVFEFLHQDLKKFMDA--SALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI--NTEGAIKLADFGLARAFGVPVR----TYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-TRR-ALFPGDSE-I-DQLFRIFRTLGTPDEVVWPGVTSMPD-----YKPSFPKWARQ-D-FSKV---VPPLDE----DGRSLLSQMLHYDPNKRISAKAALAHPFF----
19	PsiBlast_PDB	80.76	53%	-53	- C1 -	-	3PJ8		CDK2_HUMAN	A:[5-287]	----FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR---ETEGVPSTAIREISLLKELNHPNIVKLLDVIH------TENKLYLVFEFLHQDLKKFMDA--SALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI--NTEGAIKLADFGLARAFGV------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-TRR-ALFPGDSE-I-DQLFRIFRTLGTPDEVVWPGVTSMPD-----YKPSFPKWARQ-D-FSKV---VPPLDE----DGRSLLSQMLHYDPNKRISAKAALAHPFF----
7	PsiBlast_PDB	80.66	55%	-71	- C1 -	-	4AU8		CDK5_HUMAN	A:[5-291]	-SQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV---------PSSALREICLLKELKHKNIVRLHDVLH---------KLTLVFEFCDQDLKKYFDS--CN-GDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLI--NRNGELKLADFGLARAFGIPVR------SAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGR-PLFPGNDV-D-DQLKRIFRLLGTPTEEQWPSMTKLPDYK---PYPMY-----P-A-TTSLVNVVP---K-LNATGRDLLQNLLKCNPVQRISAEEALQHPYFS---
5	PsiBlast_PDB	80.62	56%	-111	- C1 -	-	2QKR	-	?	A:[19-304]	LMEKY--LEKVGEG---VVYKAKD-SQ-RIVALKRI----------STAIREISLLKELHHPNIVSLIDVIH------SE-CLTLVFEFMEKDLKKVLDE--NK-TGLQDSQIKIYLYQLLRGVAHCHQHRILHRDLKPQNLLI--NSD-ALKLADFGLARAFGIPVR---------VVTLWYRAPDVLMGSKKYSTSVDIWSIGCIFAEMI-TGK-PLFPGVTD-D-DQLPKIFSILGTPNPREWPQVQELP-----LWKQRTFQVFEK-KPWSSI---IPGFCQ----EGIDLLSNMLCFDPNKRISARDAMNHPYF----
34	HHSearch	80.43	54%	-51	- C1 -	-	4EK4		CDK2_HUMAN	A:[3-289]	--ENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKI---------PSTAIREISLLKELNHPNIVKLLDVIH------TENKLYLVFEFLHQDLKKFMDA--SALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI--NTEGAIKLADFGLARAFGVPVR----TYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-TRR-ALFPGDSE-I-DQLFRIFRTLGTPDEVVWPGVTSMPDYKPS----------FP-K-WARQDF-SKVVPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQD--
31	HHSearch	79.06	56%	-71	- C1 -	-	4AU8		CDK5_HUMAN	A:[5-293]	-SQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV---------PSSALREICLLKELKHKNIVRLHDVLH---------KLTLVFEFCDQDLKKYFDS--CN-GDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLI--NRNGELKLADFGLARAFGIPVR------SAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELA-NAG-RPLFPGNDVD-DQLKRIFRLLGTPTEEQWPSMTKLPDYKPYPMY--------P-A-TTS---LVNVVPK-LNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDF-
18	PsiBlast_PDB	78.89	53%	-49	- C1 -	-	5K4J		CDK2_HUMAN	A:[5-287]	----FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR-------VPSTAIREISLLKELNHPNIVKLLDVIH------TENKLYLVFEFLHQDLKKFMDA--SALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI--NTEGAIKLADFGLARA--------------EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMV-TRR-ALFPGDSE-I-DQLFRIFRTLGTPDEVVWPGVTSMPD-----YKPSFPKWARQ-D-FSKV---VPPLDE----DGRSLLSQMLHYDPNKRISAKAALAHPFF----
15	PsiBlast_PDB	76.52	55%	-15	- C1 -	-	5HQ0		CDK1_HUMAN	A:[9-293]	----YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLM------QDSRLYLIFEFLSMDLKKYLDSIPPG-QYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLI--DDKGTIKLADFGLARAFGIPIR----VYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELA-TKK-PLFHGDSE-I-DQLFRIFRALGTPNNEVWPEVESLQDYKNTF----------P-K-WKP--GSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN---
14	PsiBlast_PDB	76.52	55%	-15	- C1 -	-	4Y72		CDK1_HUMAN	A:[9-293]	----YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLM------QDSRLYLIFEFLSMDLKKYLDSIPPG-QYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLI--DDKGTIKLADFGLARAFGIPIR----VYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELA-TKK-PLFHGDSE-I-DQLFRIFRALGTPNNEVWPEVESLQDYKNTF----------P-K-WKP--GSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN---
17	PsiBlast_PDB	74.90	55%	-15	- C1 -	-	4YC3		CDK1_HUMAN	A:[9-293]	----YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLM------QDSRLYLIFEFLSMDLKKYLDSIPPG-QYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLI--DDKGTIKLADFGLARAFGIPIR----VYT---VTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELA-TKK-PLFHGDSE-I-DQLFRIFRALGTPNNEVWPEVESLQDYKNTF----------P-K-WKP--GSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN---
38	HHSearch	71.74	52%	-47	- C1 -	-	3GC0		?	A:[34-325]	--DRYRRITKLGEGTYGEVYKAIDTVTNETVAIKRIRLEH-------TAIREVSLLKELQHRNIIELKSVIH------HNHRLHLIFEYAENDLKKYMDK--N--PDVSMRVIKSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSV-ETPVLKIGDFGLARAF-------------EIITLWYRPPEILLGSRHYSTSVDIWSIACIWAEML-MKT-PLFPGDSE-I-DQLFKIFEVLGLPDDTTWPGVTALPDWKQSF----------P-K-FRGKTLKRVLGAL-LDDEGLDLLTAMLEMDPVKRISAKNALEHPYFSHN-
37	HHSearch	69.65	36%	-109	- C1 -	-	4BGQ		CDKL5_HUMAN	A:[11-301]	-MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFK-------VKETTLRELKMLRTLKQENIVELKEAFR------RRGKLYLVFEYVEKNMLELLEE--MP-NGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLI--SHNDVLKLCDFGFARNLSE--------------TRWYRSPELLLGA-PYGKSVDMWSVGCILGELS-DGQ-PLFPGESE-I-DQLFTIQKVLGPLPSEQMKLFYSNPRFHG-LRFPAV---NHP-Q-SL----ERRYLGI-LNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ-
27	HHSearch	58.10	36%	1	- C1 -	-	5BYZ		MK07_HUMAN	A:[5-302]	-GDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHS--S--QPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLV--NENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEML-ARR-QLFPGKNY-V-HQLQLIMMVLGTPSPAVIQAVGAERV--RAYI-QSLPPRQPV-P-WET------VYPG-ADRQALSLLGRMLRFEPSARISAAAALRHPFLAK--