@TOME V2.3
(Mar 2018)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : B0VL64: (2017-10-31 )
MTELTPYHEDQELDNNTSDNIHFRDILEQHISRRSLITKAASGAVALTLASTLTGCNDNDDDSGSNNGGTTPVDPNKKPEKLTFTPVAKNLNDIVTVPEGYEANVIYALGDSINPRVGDWDDNNIPSGPSFQFRSGDCHDGMHYFGLNTSTNRFDETVSAQGLLVMNHEYINQTFLHPKGPTKVDGRRPEDEVIRETNANGVSVIHIKKDPTTQKVEIIKNSIFNRRITASTVMEFAGAAAGSSLLATRFSPAGRQTRGTHNNCGNGYTPWGTYLTTEENFIGYFQRSGSDEYARTDAEKITLKRYGLGVKKDEPYLYEKDEKGAPKKDKDGKIIYLKDKNGELIPNVDEQGRQIYLGTSSRYGWETAIGQVESQDLYDRWNADVKAAQATQDYRNGPNTFGWMVEIDPFDGRQNPVKRTSLGRFAHEDSACRAVVGQPLAFYMGDDSRGEYIYKFVSTAVWDTKDINGGYTAGDKYMNAGKLYVAKFNNDGSGQWIELAYGKNGLNESNTTYPFKSQADVVTFARLAADSVGATKMDRPEWCTINPLNGEIYVTLTNNSNRGKDYATDAANPRNYTDLYAGTKEQKGNVNGHIIRFKETDDKTTAETFKWDIYLFGAEAAMASNINLSGLTDNNDFSSPDGMWFDPRGVLWIETDDGAYTDVTNCMMLAALPGQIGDGGTATTSNGQQTITGAKVTDATLRRFLVGPKQCEITGIAMTPDYKAIFINVQHPGEDSPSYAKPESNWPATQKDPSNKTARPRSATVVITRKDGGVIAG

Atome Classification :

(20 SA) -------------------------------------------.........10........20.--.......30........40.....-------------...50........60........70........80........90.-......---------.100.......110.......--120--.......130.......-----140.......150.......160.......170.......180.......190-------------.......200...--------....210.......220.......230.......240.----------.....-----.250.......260....------...270.......280.-......290.......300.......310--.......320-----.......330--........340.......350.......360.......370......-.380.......390.......400...-----------....410-----.......420.......430...-....440.......450...--------....460.......470--....--------.....480-........490------.--------........-----500---.......510.......520.....------..530.--------......540...----....550.......560--.--------..-.-...570.......580........590.......600.......610.......620..---.....630-.........640......-.----650.......-----660.....--..670.......680.......690.......700.....-..710.......-720--........730.......740.......750----.......760.......770.....---------------
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) -------------------------------------------MTELTPYHEDQELDNNTSDNIH--FRDILEQHISRRSLITKAASGAVA-------------LTLASTLTGCNDNDDDSGSNNGGTTPVDPNKKPEKLTFTPVAKNLN-DIVTVP---------EGYEANVIYALGDSINPRVGD--WDD--NNIPSGPSFQFRSGDCH-----DGMHYFGLNTSTNRFDETVSAQGLLVMNHEYINQTFLHPKGPTKVDGRRPEDE-------------VIRETNANGVSVI--------HIKKDPTTQKVEIIKNSIFNRRITASTVMEFAGAAAGS----------SLLAT-----RFSPAGRQTRGTHNNCGN------GYTPWGTYLTTEENFIG-YFQRSGSDEYARTDAEKITLKRYGLGVKK--DEPYLYEKDE-----KGAPKKDKD---GKIIYLKDKNGELIPNVDEQGRQIYLGTSSRYGWETAIGQVESQDLY-DRWNADVKAAQATQDYRNGPNTFGWMV-----------EIDPFDG-----RQNPVKRTSLGRFAHEDSACRAV-VGQPLAFYMGDDSRGEYIYK--------FVSTAVWDTKDINGG----YTAG--------DKYMNAG--KLYVAKFNN--------D--------GSGQWIEL-----AYG---KNGLNESNTTYPFKSQADVVTFARL------AADSVG--------ATKMDRPEWCTI----NPLNGEIYVTLTNNSNR--G--------KD-Y-ATDAANPRNYTDLYA-GTKEQKGNVNGHIIRFKETDDKTTAETFKWDIYLFGAEAAMAS---NINLSG---LTDNNDFSSPDGMWFDPR-G----VLWIETDDGA-----YTDVTNCM--MLAALPGQIGDGGTATTSNGQQTITGAKVTDATLRRFLVG-PKQCEITGIAMT-PD---YKAIFINVQHPGEDSPSYAKPESNWPATQKD----PSNKTARPRSATVVITRKDGGVIAG---------------
16 Fugue 74.4638% 17 - C4 - - 3ZWU ? A:[9-588] -----------------------------------------------------------------------------------------------------------------------------------------RLLGFDSIPAATT-DTISLP---------KGYKSSVLISWGQPLHKNGPA--FDP--SGNGTAAAQEVQFGDNN-----DGMSLFEFPG--------EKNRALMAINNEYTNYRYLYPHGGM----PQSAED-------------VRKALACEGVSVI--------EVQRKN--GQWQFVQGSRYNRRIHGNSPLRISGPAAGH----------ELMKT-----SADKHGKKVLGTFQNCAN------GKTPWGTYLTCEENFTD-CFGSSNAQ-----QQFDPAQKRYGVS----------------------------------------------------------AASREINWHPF---------D-PRFDM--------AKNPNELNRHGWVV-----------EIDPFDP-----QSTPVKRTALGRFKHENAALAET-DDGRAVVYMGDDERGEFIYK--------FVSRDKINHRN--------AKAN--------RDILDHG--TLYVARFDAGDGNPDHPK--------GQGQWIEL-----THG---KNGIDASS---GFADQAEVLIHARL------AASVVG--------ATRMDRPEWIVV----SPKDGQVYCTLTNNAKR--G--------EDGQ-PVGGPNPR-------------EKNVYGQILRWRTDRDDHASKTFAWDLFVVAGNPSVHA---GTPKGGSSNITPQNMFNSPDGLGFDKA-G----RLWILTDGD-------------------------SSNAGDFAGMGNNQMLCADPATGEIRRFMVG-PIGCEVTGISFS-PD---QKTLFVGIQHPGENGGS------TFPEHLPN----G-----KPRSSVMAITREDGGIVGAHH-------------
27 HHSearch 73.8439% 15 - C4 - - 4A9V ? A:[8-585] ----------------------------------------------------------------------------------------------------------------------------------------SRLLGFDSIPAATT-DTISLP---------KGYKSSVLISWGQPLHKNGPA--FDP--SGNGTAAAQEVQFGDNN-----DGMSLFEFPG--------EKNRALMAINNEYTNYRYLYPHGG----MPQSAED-------------VRKALACEGVSVI--------EVQRK--NGQWQFVQGSRYNRRIHGNSPLRISGPAAGH----------ELMKT-----SADKHGKKVLGTFQNCAN------GKTPWGTYLTCEENFTD-CFGSSNAQ-----QQFDPAQKRYGVSAA----------------------------------------------------------SREINWHPFDP----------RFDMA--------KNPNELNRHGWVV-----------EIDPFDP-----QSTPVKRTALGRFKHENAALAET-DDGRAVVYMGDDERGEFIYK--------FVSRDKINHRN---A----KANR---------DILDHG--TLYVARFDA--------GDGNPDHPKGQGQWIEL-----THG---KNGI---DASSGFADQAEVLIHARL------AASVVG--------ATRMDRPEWIVV----SPKDGQVYCTLTNNAKR--G--------ED-GQPVGGPNPREK-------------NVYGQILRWRTDRDDHASKTFAWDLFVVAGNPSVHAGTPKGGSSN---ITPQNMFNSPDGLGFDKA-G----RLWILTDGDSSNAGDFAGMGNNQ--MLCADPA-----------------------TGEIRRFMVG-PIGCEVTGISFS-PD---QKTLFVGIQHPGENGG------STFPEHL---------PNGKPRSSVMAITREDGGIVG----------------
26 HHSearch 73.5839% 15 - C4 - - 4AMF ? A:[4-581] ----------------------------------------------------------------------------------------------------------------------------------------SRLLGFDSIPAATT-DTISLP---------KGYKSSVLISWGQPLHKNGPA--FDP--SGNGTAAAQEVQFGDNN-----DGMSLFEFPG--------EKNRALMAINNEYTNYRYLYPHGG----MPQSAED-------------VRKALACEGVSVI--------EVQRK--NGQWQFVQGSRYNRRIHGNSPLRISGPAAGH----------ELMKT-----SADKHGKKVLGTFQNCAN------GKTPWGTYLTCEENFTD-CFGSSNAQ-----QQFDPAQKRYGVSAA----------------------------------------------------------SREINWHPFDP----------RFDMA--------KNPNELNRHGWVV-----------EIDPFDP-----QSTPVKRTALGRFKHENAALAET-DDGRAVVYMGDDERGEFIYK--------FVSRDKINHRN---A----KANR---------DILDHG--TLYVARFDA--------GDGNPDHPKGQGQWIEL-----THG---KNGI---DASSGFADQAEVLIHARL------AASVVG--------ATRMDRPEWIVV----SPKDGQVYCTLTNNAKR--G--------ED-GQPVGGPNPREK-------------NVYGQILRWRTDRDDHASKTFAWDLFVVAGNPSVHAGTPKGGSSN---ITPQNMFNSPDGLGFDKA-G----RLWILTDGDSSNAGDFAGMGNNQ--MLCADPA-----------------------TGEIRRFMVG-PIGCEVTGISFS-PD---QKTLFVGIQHPGENGG------STFPEHL---------PNGKPRSSVMAITREDGGIVG----------------
13 PsiBlast_CBE 68.9731% 18 - C4 - - 4ALF ? B:[11-585] -------------------------------------------------------------------------------------------------------------------------------------------LGFDSIPAATT-DTISLP---------KGYKSSVLISWGQPLHKNGPA--FDP--SGNGTAAAQEVQFGDNN-----DGMSLFEFPGEKNR--------ALMAINNEYTNYRYLYPHGGMP----QSAED-------------VRKALACEGVSVI--------EVQR--KNGQWQFVQGSRYNRRIHGNSPLRISGPAAGH----------ELMKT-----SADKHGKKVLGTFQNCAN------GKTPWGTYLTCEENFTD-CFGSSNAQQ--QFDPAQ---KRYGVSAAS--REINWHPFD---------PRFD---------MAKNPN-EL----------------NRHGWVVEIDPFDPQ-------------------------------------------------------STPVKRTALGRFKHENAALAET-DDGRAVVYMGDDERGEFIYK--------FVSRDKINHRNAK--------AN--------RDILDHG--TLYVARFDAGDGNPDHPK--------GQGQWIEL-----THG---KNGIDASSG---FADQAEVLIHARL------AASVVG--------ATRMDRPEWIVV----SPKDGQVYCTLTNNAKR--G--------EDGQ-PVGGPNPR-------------EKNVYGQILRWRTDRDDHASKTFAWDLFVVAGNPSVHA---GTPKGGSSNITPQNMFNSPDGLGFDKA-G----RLWILTDG---------DSSNAG--DFAGM--------------GNNQMLCADPATGEIRRFMVG-PIGCEVTGISFS-PD---QKTLFVGIQHPGENG------GSTFP--EHL----PNGK---PRSSVMAITREDGGIVG----------------
2 PsiBlast_PDB 68.9431% 18 - C4 - - 4A9V ? A:[11-585] -------------------------------------------------------------------------------------------------------------------------------------------LGFDSIPAATT-DTISLP---------KGYKSSVLISWGQPLHKNGPA--FDP--SGNGTAAAQEVQFGDNN-----DGMSLFEFPGEKNR--------ALMAINNEYTNYRYLYPHGGMP----QSAED-------------VRKALACEGVSVI--------EVQR--KNGQWQFVQGSRYNRRIHGNSPLRISGPAAGH----------ELMKT-----SADKHGKKVLGTFQNCAN------GKTPWGTYLTCEENFTD-CFGSSNAQQ--QFDPAQ---KRYGVSAAS--REINWHPFD---------PRFD---------MAKNPN-EL----------------NRHGWVVEIDPFDPQ-------------------------------------------------------STPVKRTALGRFKHENAALAET-DDGRAVVYMGDDERGEFIYK--------FVSRDKINHRNAK--------AN--------RDILDHG--TLYVARFDAGDGNPDHPK--------GQGQWIEL-----THG---KNGIDASSG---FADQAEVLIHARL------AASVVG--------ATRMDRPEWIVV----SPKDGQVYCTLTNNAKR--G--------EDGQ-PVGGPNPR-------------EKNVYGQILRWRTDRDDHASKTFAWDLFVVAGNPSVHA---GTPKGGSSNITPQNMFNSPDGLGFDKA-G----RLWILTDG---------DSSNAG--DFAGM--------------GNNQMLCADPATGEIRRFMVG-PIGCEVTGISFS-PD---QKTLFVGIQHPGENG------GSTFP--EHL----PNGK---PRSSVMAITREDGGIVG----------------
1 PsiBlast_PDB 68.8131% 18 - C4 - - 3ZWU ? A:[11-585] -------------------------------------------------------------------------------------------------------------------------------------------LGFDSIPAATT-DTISLP---------KGYKSSVLISWGQPLHKNGPA--FDP--SGNGTAAAQEVQFGDNN-----DGMSLFEFPGEKNR--------ALMAINNEYTNYRYLYPHGGMP----QSAED-------------VRKALACEGVSVI--------EVQR--KNGQWQFVQGSRYNRRIHGNSPLRISGPAAGH----------ELMKT-----SADKHGKKVLGTFQNCAN------GKTPWGTYLTCEENFTD-CFGSSNAQQ--QFDPAQ---KRYGVSAAS--REINWHPFD---------PRFD---------MAKNPN-EL----------------NRHGWVVEIDPFDPQ-------------------------------------------------------STPVKRTALGRFKHENAALAET-DDGRAVVYMGDDERGEFIYK--------FVSRDKINHRNAK--------AN--------RDILDHG--TLYVARFDAGDGNPDHPK--------GQGQWIEL-----THG---KNGIDASSG---FADQAEVLIHARL------AASVVG--------ATRMDRPEWIVV----SPKDGQVYCTLTNNAKR--G--------EDGQ-PVGGPNPR-------------EKNVYGQILRWRTDRDDHASKTFAWDLFVVAGNPSVHA---GTPKGGSSNITPQNMFNSPDGLGFDKA-G----RLWILTDG---------DSSNAG--DFAGM--------------GNNQMLCADPATGEIRRFMVG-PIGCEVTGISFS-PD---QKTLFVGIQHPGENG------GSTFP--EHL----PNGK---PRSSVMAITREDGGIVG----------------
5 PsiBlast_PDB 68.6131% 17 - C4 - - 4AMF ? A:[7-581] -------------------------------------------------------------------------------------------------------------------------------------------LGFDSIPAATT-DTISLP---------KGYKSSVLISWGQPLHKNGPA--FDP--SGNGTAAAQEVQFGDNN-----DGMSLFEFPGEKNR--------ALMAINNEYTNYRYLYPHGGMP----QSAED-------------VRKALACEGVSVI--------EVQR--KNGQWQFVQGSRYNRRIHGNSPLRISGPAAGH----------ELMKT-----SADKHGKKVLGTFQNCAN------GKTPWGTYLTCEENFTD-CFGSSNAQQ--QFDPAQ---KRYGVSAAS--REINWHPFD---------PRFD---------MAKNPN-EL----------------NRHGWVVEIDPFDPQ-------------------------------------------------------STPVKRTALGRFKHENAALAET-DDGRAVVYMGDDERGEFIYK--------FVSRDKINHRNAK--------AN--------RDILDHG--TLYVARFDAGDGNPDHPK--------GQGQWIEL-----THG---KNGIDASSG---FADQAEVLIHARL------AASVVG--------ATRMDRPEWIVV----SPKDGQVYCTLTNNAKR--G--------EDGQ-PVGGPNPR-------------EKNVYGQILRWRTDRDDHASKTFAWDLFVVAGNPSVHA---GTPKGGSSNITPQNMFNSPDGLGFDKA-G----RLWILTDG---------DSSNAG--DFAGM--------------GNNQMLCADPATGEIRRFMVG-PIGCEVTGISFS-PD---QKTLFVGIQHPGENG------GSTFP--EHL----PNGK---PRSSVMAITREDGGIVG----------------
15 PsiBlast_CBE 68.6031% 19 - C4 - - 4AMF ? B:[7-581] -------------------------------------------------------------------------------------------------------------------------------------------LGFDSIPAATT-DTISLP---------KGYKSSVLISWGQPLHKNGPA--FDP--SGNGTAAAQEVQFGDNN-----DGMSLFEFPGEKNR--------ALMAINNEYTNYRYLYPHGGMP----QSAED-------------VRKALACEGVSVI--------EVQR--KNGQWQFVQGSRYNRRIHGNSPLRISGPAAGH----------ELMKT-----SADKHGKKVLGTFQNCAN------GKTPWGTYLTCEENFTD-CFGSSNAQQ--QFDPAQ---KRYGVSAAS--REINWHPFD---------PRFD---------MAKNPN-EL----------------NRHGWVVEIDPFDPQ-------------------------------------------------------STPVKRTALGRFKHENAALAET-DDGRAVVYMGDDERGEFIYK--------FVSRDKINHRNAK--------AN--------RDILDHG--TLYVARFDAGDGNPDHPK--------GQGQWIEL-----THG---KNGIDASSG---FADQAEVLIHARL------AASVVG--------ATRMDRPEWIVV----SPKDGQVYCTLTNNAKR--G--------EDGQ-PVGGPNPR-------------EKNVYGQILRWRTDRDDHASKTFAWDLFVVAGNPSVHA---GTPKGGSSNITPQNMFNSPDGLGFDKA-G----RLWILTDG---------DSSNAG--DFAGM--------------GNNQMLCADPATGEIRRFMVG-PIGCEVTGISFS-PD---QKTLFVGIQHPGENG------GSTFP--EHL----PNGK---PRSSVMAITREDGGIVG----------------
4 PsiBlast_PDB 68.4931% 18 - C4 - - 4ALF ? A:[11-585] -------------------------------------------------------------------------------------------------------------------------------------------LGFDSIPAATT-DTISLP---------KGYKSSVLISWGQPLHKNGPA--FDP--SGNGTAAAQEVQFGDNN-----DGMSLFEFPGEKNR--------ALMAINNEYTNYRYLYPHGGMP----QSAED-------------VRKALACEGVSVI--------EVQR--KNGQWQFVQGSRYNRRIHGNSPLRISGPAAGH----------ELMKT-----SADKHGKKVLGTFQNCAN------GKTPWGTYLTCEENFTD-CFGSSNAQQ--QFDPAQ---KRYGVSAAS--REINWHPFD---------PRFD---------MAKNPN-EL----------------NRHGWVVEIDPFDPQ-------------------------------------------------------STPVKRTALGRFKHENAALAET-DDGRAVVYMGDDERGEFIYK--------FVSRDKINHRNAK--------AN--------RDILDHG--TLYVARFDAGDGNPDHPK--------GQGQWIEL-----THG---KNGIDASSG---FADQAEVLIHARL------AASVVG--------ATRMDRPEWIVV----SPKDGQVYCTLTNNAKR--G--------EDGQ-PVGGPNPR-------------EKNVYGQILRWRTDRDDHASKTFAWDLFVVAGNPSVHA---GTPKGGSSNITPQNMFNSPDGLGFDKA-G----RLWILTDG---------DSSNAG--DFAGM--------------GNNQMLCADPATGEIRRFMVG-PIGCEVTGISFS-PD---QKTLFVGIQHPGENG------GSTFP--EHL----PNGK---PRSSVMAITREDGGIVG----------------
3 PsiBlast_PDB 68.4931% 19 - C4 - - 4A9X ? A:[11-585] -------------------------------------------------------------------------------------------------------------------------------------------LGFDSIPAATT-DTISLP---------KGYKSSVLISWGQPLHKNGPA--FDP--SGNGTAAAQEVQFGDNN-----DGMSLFEFPGEKNR--------ALMAINNEYTNYRYLYPHGGMP----QSAED-------------VRKALACEGVSVI--------EVQR--KNGQWQFVQGSRYNRRIHGNSPLRISGPAAGH----------ELMKT-----SADKHGKKVLGTFQNCAN------GKTPWGTYLTCEENFTD-CFGSSNAQQ--QFDPAQ---KRYGVSAAS--REINWHPFD---------PRFD---------MAKNPN-EL----------------NRHGWVVEIDPFDPQ-------------------------------------------------------STPVKRTALGRFKHENAALAET-DDGRAVVYMGDDERGEFIYK--------FVSRDKINHRNAK--------AN--------RDILDHG--TLYVARFDAGDGNPDHPK--------GQGQWIEL-----THG---KNGIDASSG---FADQAEVLIHARL------AASVVG--------ATRMDRPEWIVV----SPKDGQVYCTLTNNAKR--G--------EDGQ-PVGGPNPR-------------EKNVYGQILRWRTDRDDHASKTFAWDLFVVAGNPSVHA---GTPKGGSSNITPQNMFNSPDGLGFDKA-G----RLWILTDG---------DSSNAG--DFAGM--------------GNNQMLCADPATGEIRRFMVG-PIGCEVTGISFS-PD---QKTLFVGIQHPGENG------GSTFP--EHL----PNGK---PRSSVMAITREDGGIVG----------------
14 PsiBlast_CBE 68.3731% 18 - C4 - - 3ZWU ? B:[11-585] -------------------------------------------------------------------------------------------------------------------------------------------LGFDSIPAATT-DTISLP---------KGYKSSVLISWGQPLHKNGPA--FDP--SGNGTAAAQEVQFGDNN-----DGMSLFEFPGEKNR--------ALMAINNEYTNYRYLYPHGGMP----QSAED-------------VRKALACEGVSVI--------EVQR--KNGQWQFVQGSRYNRRIHGNSPLRISGPAAGH----------ELMKT-----SADKHGKKVLGTFQNCAN------GKTPWGTYLTCEENFTD-CFGSSNAQQ--QFDPAQ---KRYGVSAAS--REINWHPFD---------PRFD---------MAKNPN-EL----------------NRHGWVVEIDPFDPQ-------------------------------------------------------STPVKRTALGRFKHENAALAET-DDGRAVVYMGDDERGEFIYK--------FVSRDKINHRNAK--------AN--------RDILDHG--TLYVARFDAGDGNPDHPK--------GQGQWIEL-----THG---KNGIDASSG---FADQAEVLIHARL------AASVVG--------ATRMDRPEWIVV----SPKDGQVYCTLTNNAKR--G--------EDGQ-PVGGPNPR-------------EKNVYGQILRWRTDRDDHASKTFAWDLFVVAGNPSVHA---GTPKGGSSNITPQNMFNSPDGLGFDKA-G----RLWILTDG---------DSSNAG--DFAGM--------------GNNQMLCADPATGEIRRFMVG-PIGCEVTGISFS-PD---QKTLFVGIQHPGENG------GSTFP--EHL----PNGK---PRSSVMAITREDGGIVG----------------
17 Fugue 40.9431%-207 - C5 - - 1T6O - B:[1-19] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QDSRRSADA-------------LLRLQAMAGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23 Fugue 35.5118% 34 - C3 - - 3V97 RLMKL_ECOLI A:[1-703] ------------------------------------------AMNSLFASTAR-----------G--LEELLKTELENL--------GAVE-------------CQVVQ---------------GGVHFKGDTRLVYQSLMWSRLASRIM-LPLGEC---------KVYSDLDLYLGVQAIN-------WTE--MFNPGAT---------------FAVHFSGLNDTIRN-----SQYGAMKVKDAIVDAFTRKNLPRPNVDRDAPDIR-------------VNVWLHKETASIALDLSGDGLHLRGYRDRAGIAPIK------ETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIE-----AAMLATDRAPGLHRG------------RWG--------FSG-WAQH---DEAIWQEVKAEAQTRARKGLAE--YSSHFYGSDSDARVIQRARTNARLAGIGELITFEVKDVAQLTNPLPKGPYGTVLSNPPYG----------ESEP-ALIALHSLLGRIMKNQFGGWNLSLFSA-----------SPDLLSC-----LQLRADKQYKAKNGPLDCVQKNYHVAESMV---AEDYTNRLRKN--------LKKFEKWARQEGIEC----YRLY--------DADLPEY--NVAVDRYAD---------------------WVVV-----QE--------------YAHKARQRLFDIIAA------TISVLGIAPNKLVLKTREEKGEFLEV----TEYNAHLWVNLTDYLDT--GLFLDHRIARR-M-LGQMSKGKDFLNLFS-YT----GSATVHAGL---GGARSTTTVDMSRTYLEWAERNLRL---N-GLTG----RAHRLIQADCLAWLREA-NEQFDLIFIDPPTFS-----AFDVQRDHLALMKDLKRLLRAGGTIMFSNNKR---GFRMDLDGLAKL--G-LKAQEITQKTLS-QD---FA-------------------------------------RNRQIHNCWLITAA----------------------
19 Fugue 29.6218% 32 - C4 - - 5JSD ? A:[172-719] -------------------------------------------QTQYYLKYFNPEIVYPKNARIM--LDN--------------------G-------------DIVRSTVVN---NTSNPNVDMTGWVKVSSVSQIFDETYNITQSVIN-GNLITV---------DNFGAK-----GDGVTDDSAA--FQAYCDSALTGQNLYLGAKG-----------RYILKNQVDLKGKGLVGNGCGKVSEFYYNLGCID------VDGSSPDLQ--------------------GKTAFI--------NC--GPTIQ---------------------------------------NLTAR-----CSNGAGKQ-------------------------------VS-FIEIDGY----LANIDHITLINFY-----------------------------------NQIVVK----QALVGFNFTNAWLYY-----------------------------------------SQNAGIYC-----------E-DPLN-----------RVSTTGTFHN----IYFQ-LGDGHAMIFDRDVHGCDFDN--------IIFE------SMNGG----IKA---------RTVAHCGFGKFWCENLKT--------A--------TSKDWLEVTGANSCYG---NSFTGYVKLLGGWTSKTSP-TLDSL------PTNNYG--------GVSVSAEGISIV----NAGNKAKMLMLPSGFKT--G--------NA-T-IDETHISSSTVTPLV-KRRVIGADSSG---AQYLASDTYTKLSRKWGTYNHGSNNAGAF---Y-APMM---LTYDQSFSTPQ----NNN-G----WKIVKESTGV-----YRVERV--------------SGNTSVITNGHIVVGSPLMGSR------LG-TGTGATHGIQMI-ET---YA--------GSWTSYTEA---AGFKVFWRD----SSNALVDPHRFTVAFTATS---------------------
30 HHSearch 28.7720% -94 - C4 - - 5GX2 ? A:[211-276] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGYPDGQTIDEE-G----NLWVAVFQ------------GQR--IIKISTQQP---E------------------VLLDTV-KI-P-DPQVTSVAFGGPN---LDELYVTSAG-----------------------------------------------------------------
39 HHSearch 28.3218%-129 - C4 - - 2P4O - ? A:[72-133] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKVSGLAFTSN-G----DLVATGWNAD----------SIP--VVSLVKSD----G-------------------TVETLLTL-PDAIFLNGITPL-SD---TQ-YLTA--------------------------------------------------------------------
29 HHSearch 28.0320% -95 - C4 - - 5GTQ ? A:[211-276] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGYPDGQTIDEE-G----NLWVAVFQ------------GQR--IIKISTQQP---E------------------VLLDTV-KI-P-DPQVTSVAFGGPN---LDELYVTSAG-----------------------------------------------------------------
45 HHSearch 26.0817% -88 - C4 - - 2P4O ? A:[212-278] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TNIDDFAFDVE-G----NLYGATHI------------YNS--VVRIAPD-----R-------------------STTIIAQAEQGVIGSTAVAFG-QTEGDCTAIYVVTNG-----------------------------------------------------------------
22 Fugue 25.6215% 63 - C1 - - 2IPC - SECA_THET8 A:[1-939] MLGLLRRLFDNNEREIARYYKQVVEPVNRLEAEVEKLPDLAAAYRELKEKHEKGASLDELLPMAFALTRESAKRYLGMRHFDVQLIGGAVLHEGKIAEMKTGEGKTLVATLAVALNAL--TGKGVHVVTVNDYLARRDAEWMGPVYRGLGLSVGVIQHASTPAERRKAYLADVTYVT----NSELGFDYLRD--NMAISPDQLVLRHDHPLHYAIIDEVDSILIDEARTPLIISGPAEKATDLYYKMAEIAKKLERGLPAEPGVRKEPTGDYTVEEKNRSVHLTLQGIAKAEKLL--------GIEGLFSPENMELAHMLIQAIRAKELYHRDRDYIVQDG----------QVIIVDEFTGRLMPGRRYGEGLHQAIEAKEGVRIERENQTLATITYQNFFRLYEKRAGMTGTAKTEEKEFQ-EIYGMDVVVVPTNRPVIRKDF-----PDVVYRTEK---GKFYAVVEEIAEKYER----GQPVLVGTISIEKSERLSQMLKEPRLYLPRLEMRLELFKKASQKQQGPEWERLRKLLERPAQLKDEDLAPFEGLIPPKGNLRTAWEGLKRAVHTLAVLRQG-IPHQVLNAKHHAREAEIVAQAGRSKTVTIATNMAGRGTDIKLGGNPEYLAAALLEKEGFDRYEWKV--ELFIKKMVA--------G--------KEEEARAL-----AQELGIREELLERIREIREECKQDEERVRALGGLFIIGTERHE--------SRRIDNQLRGRAGRQGDPGGSRFYVSFDDDLMRLFA--------SD-R-VIAMLDRMGFDDSEPIEHPMVTRSIERAQKRVEDRNFAIRKQLLQFDDVLSRQREVIYA---QRRLIL---LGKDEEVKEAAIGMVEET-V----ASLAENFLNP-----EVHPED-W--DLEGLKATLLDTAPQLQDFPFAELRALKAEEAVERLVEAA-LKAYEAREAELS-PP---LMRAVERFVILNVVDNAWKEHLHNLDVLRQGIFLRGYGQKDPFQEYKIEATRLFNEMVAFIKSEVAKFLFRLKVE
41 HHSearch 24.3911% -51 - C4 - - 3SOV LRP6_HUMAN A:[121-185] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDQPRAIALDPSSG----FMYWTDWGE-----------VPK--IERAGMD-----G------------------SSRFIIINS--EIYWPNGLTLD-YE---EQKLYWADA------------------------------------------------------------------