@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VQ20: (2017-11-24 )
MDKTIGIFGGGQLGRMMAQAALPLNIQCTFFEANTDCPAGVLGQVFSSQDEQGLKQFIESADVFSLEFENTPVADVDVLTQTKTLHPPRIALATAQNRLSEKALFDELAIPVAPYRAVDSLESLKKAVAELGLPIVLKTATGGYDGKGQFVLRSEDQIDTAWAELGPAKSLVAESFVKFSCEVSIIAVRGQNGEVKTWPLAENHHHNGILSHSIVPAPNSEALQPVAQDYITRLLNHLNYVGVLTLELFVTEQGLCANEMAPRVHNSGHWSIEGAVCSQFENHIRAVAGLPLGSTDVVRPTVMINIIGQHPKTKDVLALNGAHLHLYNKSERAGRKLGHITLMPVDSNELTNLCRQLAKILPEPLALTDDMTI
Atome Classification :
(23 SA)
.........10........20........30........40..---.---..---...--50.------.......60........70........80.-.......90........100.......110.......120...---....130.......140-.-.-.....150.......160.....-.-.170.......180........190-........200.......210......-.-220........230.......240.......250.-.-.-.....260.......270.......280.......290-....-...300......--.----310.--.--------.-.....320-------.......330..-......340.......350.......360.......370.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MD
K
T
I
G
I
FGG
G
Q
L
G
R
M
M
A
Q
AAL
P
L
N
I
Q
C
T
F
F
EANTDC
P
A
G
V
L
G
---
Q
---
V
F---SSQ--
D
E
Q
------
G
L
K
Q
F
I
E
SA
D
V
F
S
L
EFENTPVA
D
V
D
V
L
TQT-KTLHPP
R
I
A
L
A
T
A
Q
N
R
L
S
E
K
A
L
F
D
E
LAIPVA
P
Y
R
A
V
D
S
L
E
S
L
K
---
K
A
V
A
ELGL
P
I
V
L
K
TATG-G-Y-DGK
G
Q
F
V
L
RSEDQ
I
D
T
A
W
A
ELG
P
-
A
-
K
S
L
V
A
E
S
F
V
K
F
S
-
C
E
V
S
I
I
A
V
RGQ--NGE
V
K
T
W
PLAENHHHNGILSHSIVPAP-
N
-
S
-
E
A
L
Q
P
V
A
Q
D
Y
I
T
R
L
L
N
H
L
N
Y
V
G
V
L
T
L
E
L
F
V-TE-Q-G-L
C
A
N
E
MAPRVHNSG
H
W
S
I
E
G
A
V
C
S
Q
F
E
N
H
I
R
A
V
AGLPL-GSTD-VVR
P
T
V
M
I
N
I
IG--Q----H-PK--T--------K-
D
V
L
A
LN
G
A
-------
H
L
H
L
YNK
S
E
-RA-GRKLG
H
I
T
L
M
PV
D
S
N
E
L
T
N
L
C
R
Q
L
A
K
ILPEPLALTDDMTI
70
HHSearch
90.98
48%
-5
- C1 -
-
3AW8
1
?
A:
[1-362]
---
M
I
G
I
L
G
G
G
Q
L
G
R
M
L
A
L
A
G
Y
P
L
G
L
S
F
R
F
L
D
P
S
P
E
A
C
A
G
Q
V
G
E
L
-
V
---
V
G
---
E
F
L
--
D
E
G
------
A
L
L
R
F
A
E
G
L
A
L
V
T
Y
E
F
E
N
V
P
V
E
A
A
R
R
L
E
G
R
L
P
L
-
Y
P
P
A
K
A
L
E
V
A
Q
D
R
L
R
E
K
T
F
F
Q
G
L
G
V
P
T
P
P
F
H
P
V
D
G
P
E
D
L
E
---
E
G
L
K
R
V
G
L
P
A
L
L
K
T
R
-
R
--------
G
Q
A
L
V
R
T
E
E
E
A
L
E
A
L
K
A
L
G
G
---
R
G
L
I
L
E
G
F
V
P
F
D
-
R
E
V
S
L
L
A
V
R
G
R
--
T
G
E
V
A
F
Y
P
L
V
E
N
R
H
W
G
G
I
L
R
L
S
L
A
P
A
P
G
A
-
S
-
E
A
L
Q
K
K
A
E
A
Y
A
L
R
A
M
E
A
L
D
Y
V
G
V
L
A
L
E
F
F
Q
-
V
G
-
E
-
E
-
L
L
F
N
E
M
A
P
R
V
H
N
S
G
H
W
T
I
E
G
A
E
T
S
Q
F
E
N
H
L
R
A
V
L
G
L
P
L
-
G
S
T
A
-
P
R
G
Q
S
A
M
V
N
L
I
G
--
E
----
K
-
P
P
--
F
--------
A
-
E
V
L
K
V
E
G
A
-------
H
L
H
W
Y
G
K
A
V
-
R
P
-
G
R
K
V
G
H
I
T
L
R
R
D
G
L
K
A
L
E
E
G
L
A
R
L
S
R
L
V
S
E
----------
71
HHSearch
90.34
41%
11
- C1 -
-
4MAM
3
?
A:
[1-361]
--
M
K
I
G
I
I
G
A
G
Q
L
A
R
M
L
S
L
A
G
T
P
L
G
L
E
F
H
C
L
G
K
N
G
D
C
A
E
-
E
V
V
K
T
V
T
---
D
I
---
E
L
T
--
K
V
N
------
D
V
V
A
W
A
K
Q
F
D
V
I
T
F
E
N
E
N
I
S
H
E
L
I
K
A
I
N
H
E
V
S
V
-
Y
P
S
A
K
A
I
A
I
S
Q
D
R
L
L
E
K
S
F
M
Q
D
H
G
I
A
T
A
K
F
V
N
I
D
S
L
A
K
L
Q
---
S
A
V
D
D
H
G
L
P
A
I
L
K
T
R
-
R
F
G
-
Y
-
D
G
K
G
Q
F
V
I
R
S
Q
E
D
I
T
K
A
W
D
V
L
K
D
A
P
-
D
G
L
I
Y
E
A
F
V
D
-
F
D
Y
E
V
S
Q
I
C
T
A
D
L
--
K
G
N
I
A
F
Y
P
L
A
R
N
T
H
K
Q
G
I
I
V
E
S
E
A
P
F
E
---
N
-
V
V
L
A
E
K
A
Q
Q
I
A
K
I
L
V
K
E
F
A
Y
V
G
T
L
A
I
E
F
F
V
-
K
G
-
D
-
E
-
L
I
V
N
E
I
A
P
R
V
H
N
S
G
H
W
S
I
D
G
A
V
T
S
Q
F
E
N
H
V
R
A
I
A
G
L
I
L
-
G
D
T
T
-
S
-
R
K
T
V
M
L
N
C
I
G
--
G
----
M
-
P
A
--
T
--------
K
-
D
L
A
A
L
D
R
V
-------
K
I
H
S
Y
N
K
E
P
-
R
K
-
G
R
K
V
G
H
L
N
L
N
L
N
D
E
T
D
E
-
Y
Q
L
L
Q
V
K
K
L
I
A
L
----------
6
PsiBlast_PDB
89.90
41%
-4
- C1 -
-
4M9U
1
?
A:
[3-359]
----
I
G
I
I
G
A
G
Q
L
A
R
M
L
S
L
A
G
T
P
L
G
L
E
F
H
C
L
G
K
N
G
D
C
A
E
E
V
V
K
---
T
---
V
T
---
D
I
E
--
L
T
K
V
N
D
V
V
A
W
A
K
Q
F
----
D
V
I
T
F
E
N
E
N
I
S
H
E
L
I
K
A
I
N
H
E
-
V
S
V
Y
P
S
A
K
A
I
A
I
S
Q
D
R
L
L
E
K
S
F
M
Q
D
H
G
I
A
T
A
K
F
V
N
I
D
S
L
A
K
L
Q
---
S
A
V
D
D
H
G
L
P
A
I
L
K
T
R
R
F
-
G
-
Y
-
D
G
K
G
Q
F
V
I
R
S
Q
E
D
I
T
K
A
W
D
V
L
K
D
-
A
P
D
G
L
I
Y
E
A
F
V
D
F
D
-
Y
E
V
S
Q
I
C
T
A
D
L
--
K
G
N
I
A
F
Y
P
L
A
R
N
T
H
K
Q
G
I
I
V
E
S
E
A
P
F
E
-
N
-
V
--
V
L
A
E
K
A
Q
Q
I
A
K
I
L
V
K
E
F
A
Y
V
G
T
L
A
I
E
F
F
V
-
K
G
-
D
-
E
-
L
I
V
N
E
I
A
P
R
V
H
N
S
G
H
W
S
I
D
G
A
V
T
S
Q
F
E
N
H
V
R
A
I
A
G
L
I
L
-
G
D
T
--
T
S
R
K
T
V
M
L
N
C
I
G
--
G
----
M
-
P
A
--
T
--------
K
-
D
L
A
A
L
D
R
V
-------
K
I
H
S
Y
N
K
E
P
-
R
K
-
G
R
K
V
G
H
L
N
L
N
L
N
D
E
T
D
E
Y
Q
L
L
-
Q
V
K
K
L
I
------------
4
PsiBlast_PDB
89.21
41%
-4
- C1 -
-
4MA0
3
?
A:
[3-359]
----
I
G
I
I
G
A
G
Q
L
A
R
M
L
S
L
A
G
T
P
L
G
L
E
F
H
C
L
G
K
N
G
D
C
A
E
E
V
V
K
---
T
---
V
T
---
D
I
E
--
L
T
K
V
N
D
V
V
A
W
A
K
Q
F
----
D
V
I
T
F
E
N
E
N
I
S
H
E
L
I
K
A
I
N
H
E
-
V
S
V
Y
P
S
A
K
A
I
A
I
S
Q
D
R
L
L
E
K
S
F
M
Q
D
H
G
I
A
T
A
K
F
V
N
I
D
S
L
A
K
L
Q
---
S
A
V
D
D
H
G
L
P
A
I
L
K
T
R
R
F
-
G
-
Y
-
D
G
K
G
Q
F
V
I
R
S
Q
E
D
I
T
K
A
W
D
V
L
K
D
-
A
P
D
G
L
I
Y
E
A
F
V
D
F
D
-
Y
E
V
S
Q
I
C
T
A
D
L
--
K
G
N
I
A
F
Y
P
L
A
R
N
T
H
K
Q
G
I
I
V
E
S
E
A
P
F
E
-
N
-
V
--
V
L
A
E
K
A
Q
Q
I
A
K
I
L
V
K
E
F
A
Y
V
G
T
L
A
I
E
F
F
V
-
K
G
-
D
-
E
-
L
I
V
N
E
I
A
P
R
V
H
N
S
G
H
W
S
I
D
G
A
V
T
S
Q
F
E
N
H
V
R
A
I
A
G
L
I
L
-
G
D
T
--
T
S
R
K
T
V
M
L
N
C
I
G
--
G
----
M
-
P
A
--
T
--------
K
-
D
L
A
A
L
D
R
V
-------
K
I
H
S
Y
N
K
E
P
-
R
K
-
G
R
K
V
G
H
L
N
L
N
L
N
D
E
T
D
E
Y
Q
L
L
-
Q
V
K
K
L
I
------------
9
PsiBlast_PDB
89.15
43%
-12
- C1 -
-
3QFF
1
?
A:
[15-361]
--
K
T
I
G
I
I
G
G
G
Q
L
G
R
M
M
A
L
A
A
K
E
M
G
Y
K
I
A
V
L
D
P
T
K
N
S
P
C
A
Q
V
A
---
D
I
E
I
V
A
---
S
Y
D
--
D
L
K
------
A
I
Q
H
L
A
E
I
S
D
V
V
T
Y
E
F
E
N
I
D
Y
R
C
L
Q
W
L
E
K
H
-
A
Y
L
P
Q
G
S
Q
L
L
S
K
T
Q
N
R
F
T
E
K
N
A
I
E
K
A
G
L
P
V
A
T
Y
R
L
V
Q
N
Q
E
Q
L
T
---
E
A
I
A
E
L
S
Y
P
S
V
L
K
T
T
T
G
-
G
-
Y
-
D
G
K
G
Q
V
V
L
R
S
E
A
D
V
D
E
A
-
R
K
L
A
N
-
A
-
A
E
C
I
L
E
K
W
V
P
F
E
-
K
E
V
S
V
I
V
I
R
S
V
--
S
G
E
T
K
V
F
P
V
A
E
N
I
H
V
N
N
I
L
H
E
S
I
V
P
A
R
-
I
-
T
-
E
E
L
S
Q
K
A
I
A
Y
A
K
V
L
A
D
E
L
E
L
V
G
T
L
A
V
E
M
F
A
-
T
A
-
D
-
G
E
I
Y
I
N
E
L
A
P
R
P
H
N
S
G
H
Y
T
Q
D
A
C
E
T
S
Q
F
G
Q
H
I
R
A
I
C
N
L
P
L
-
G
E
T
N
-
L
L
K
P
V
V
M
V
N
I
L
G
--
E
----
H
-
I
E
G
V
L
--------
R
-
Q
V
N
R
L
T
G
C
-------
Y
L
H
L
Y
G
K
E
E
A
K
A
-
Q
R
K
M
G
H
V
N
I
L
------------------------------
7
PsiBlast_PDB
89.02
43%
-10
- C1 -
-
4DLK
3
?
A:
[9-355]
--
K
T
I
G
I
I
G
G
G
Q
L
G
R
M
M
A
L
A
A
K
E
M
G
Y
K
I
A
V
L
D
P
T
K
N
S
P
C
A
Q
V
A
---
D
I
E
I
V
A
---
S
Y
D
--
D
L
K
------
A
I
Q
H
L
A
E
I
S
D
V
V
T
Y
E
F
E
N
I
D
Y
R
C
L
Q
W
L
E
K
H
-
A
Y
L
P
Q
G
S
Q
L
L
S
K
T
Q
N
R
F
T
E
K
N
A
I
E
K
A
G
L
P
V
A
T
Y
R
L
V
Q
N
Q
E
Q
L
T
---
E
A
I
A
E
L
S
Y
P
S
V
L
K
T
T
T
G
-
G
-
Y
-
D
G
K
G
Q
V
V
L
R
S
E
A
D
V
D
E
A
-
R
K
L
A
N
-
A
-
A
E
C
I
L
E
K
W
V
P
F
E
-
K
E
V
S
V
I
V
I
R
S
V
--
S
G
E
T
K
V
F
P
V
A
E
N
I
H
V
N
N
I
L
H
E
S
I
V
P
A
R
-
I
-
T
-
E
E
L
S
Q
K
A
I
A
Y
A
K
V
L
A
D
E
L
E
L
V
G
T
L
A
V
E
M
F
A
-
T
A
-
D
-
G
E
I
Y
I
N
E
L
A
P
R
P
H
N
S
G
H
Y
T
Q
D
A
C
E
T
S
Q
F
G
Q
H
I
R
A
I
C
N
L
P
L
-
G
E
T
N
-
L
L
K
P
V
V
M
V
N
I
L
G
--
E
----
H
-
I
E
G
V
L
--------
R
-
Q
V
N
R
L
T
G
C
-------
Y
L
H
L
Y
G
K
E
E
A
K
A
-
Q
R
K
M
G
H
V
N
I
L
------------------------------
26
PsiBlast_CBE
88.79
43%
-9
- C1 -
-
3V4S
1
?
B:
[15-361]
--
K
T
I
G
I
I
G
G
G
Q
L
G
R
M
M
A
L
A
A
K
E
M
G
Y
K
I
A
V
L
D
P
T
K
N
S
P
C
A
Q
V
A
---
D
I
E
I
V
A
---
S
Y
D
--
D
L
K
------
A
I
Q
H
L
A
E
I
S
D
V
V
T
Y
E
F
E
N
I
D
Y
R
C
L
Q
W
L
E
K
H
-
A
Y
L
P
Q
G
S
Q
L
L
S
K
T
Q
N
R
F
T
E
K
N
A
I
E
K
A
G
L
P
V
A
T
Y
R
L
V
Q
N
Q
E
Q
L
T
---
E
A
I
A
E
L
S
Y
P
S
V
L
K
T
T
T
G
-
G
-
Y
-
D
G
K
G
Q
V
V
L
R
S
E
A
D
V
D
E
A
-
R
K
L
A
N
-
A
-
A
E
C
I
L
E
K
W
V
P
F
E
-
K
E
V
S
V
I
V
I
R
S
V
--
S
G
E
T
K
V
F
P
V
A
E
N
I
H
V
N
N
I
L
H
E
S
I
V
P
A
R
-
I
-
T
-
E
E
L
S
Q
K
A
I
A
Y
A
K
V
L
A
D
E
L
E
L
V
G
T
L
A
V
E
M
F
A
-
T
A
-
D
-
G
E
I
Y
I
N
E
L
A
P
R
P
H
N
S
G
H
Y
T
Q
D
A
C
E
T
S
Q
F
G
Q
H
I
R
A
I
C
N
L
P
L
-
G
E
T
N
-
L
L
K
P
V
V
M
V
N
I
L
G
--
E
----
H
-
I
E
G
V
L
--------
R
-
Q
V
N
R
L
T
G
C
-------
Y
L
H
L
Y
G
K
E
E
A
K
A
-
Q
R
K
M
G
H
V
N
I
L
------------------------------
10
PsiBlast_PDB
88.78
43%
-13
- C1 -
-
3R5H
2
?
A:
[15-361]
--
K
T
I
G
I
I
G
G
G
Q
L
G
R
M
M
A
L
A
A
K
E
M
G
Y
K
I
A
V
L
D
P
T
K
N
S
P
C
A
Q
V
A
---
D
I
E
I
V
A
---
S
Y
D
--
D
L
K
------
A
I
Q
H
L
A
E
I
S
D
V
V
T
Y
E
F
E
N
I
D
Y
R
C
L
Q
W
L
E
K
H
-
A
Y
L
P
Q
G
S
Q
L
L
S
K
T
Q
N
R
F
T
E
K
N
A
I
E
K
A
G
L
P
V
A
T
Y
R
L
V
Q
N
Q
E
Q
L
T
---
E
A
I
A
E
L
S
Y
P
S
V
L
K
T
T
T
G
-
G
-
Y
-
D
G
K
G
Q
V
V
L
R
S
E
A
D
V
D
E
A
-
R
K
L
A
N
-
A
-
A
E
C
I
L
E
K
W
V
P
F
E
-
K
E
V
S
V
I
V
I
R
S
V
--
S
G
E
T
K
V
F
P
V
A
E
N
I
H
V
N
N
I
L
H
E
S
I
V
P
A
R
-
I
-
T
-
E
E
L
S
Q
K
A
I
A
Y
A
K
V
L
A
D
E
L
E
L
V
G
T
L
A
V
E
M
F
A
-
T
A
-
D
-
G
E
I
Y
I
N
E
L
A
P
R
P
H
N
S
G
H
Y
T
Q
D
A
C
E
T
S
Q
F
G
Q
H
I
R
A
I
C
N
L
P
L
-
G
E
T
N
-
L
L
K
P
V
V
M
V
N
I
L
G
--
E
----
H
-
I
E
G
V
L
--------
R
-
Q
V
N
R
L
T
G
C
-------
Y
L
H
L
Y
G
K
E
E
A
K
A
-
Q
R
K
M
G
H
V
N
I
L
------------------------------
5
PsiBlast_PDB
88.45
41%
-4
- C1 -
-
4MAM
3
?
A:
[3-359]
----
I
G
I
I
G
A
G
Q
L
A
R
M
L
S
L
A
G
T
P
L
G
L
E
F
H
C
L
G
K
N
G
D
C
A
E
E
V
V
K
---
T
---
V
T
---
D
I
E
--
L
T
K
V
N
D
V
V
A
W
A
K
Q
F
----
D
V
I
T
F
E
N
E
N
I
S
H
E
L
I
K
A
I
N
H
E
-
V
S
V
Y
P
S
A
K
A
I
A
I
S
Q
D
R
L
L
E
K
S
F
M
Q
D
H
G
I
A
T
A
K
F
V
N
I
D
S
L
A
K
L
Q
---
S
A
V
D
D
H
G
L
P
A
I
L
K
T
R
R
F
-
G
-
Y
-
D
G
K
G
Q
F
V
I
R
S
Q
E
D
I
T
K
A
W
D
V
L
K
D
-
A
P
D
G
L
I
Y
E
A
F
V
D
F
D
-
Y
E
V
S
Q
I
C
T
A
D
L
--
K
G
N
I
A
F
Y
P
L
A
R
N
T
H
K
Q
G
I
I
V
E
S
E
A
P
F
E
-
N
-
V
--
V
L
A
E
K
A
Q
Q
I
A
K
I
L
V
K
E
F
A
Y
V
G
T
L
A
I
E
F
F
V
-
K
G
-
D
-
E
-
L
I
V
N
E
I
A
P
R
V
H
N
S
G
H
W
S
I
D
G
A
V
T
S
Q
F
E
N
H
V
R
A
I
A
G
L
I
L
-
G
D
T
--
T
S
R
K
T
V
M
L
N
C
I
G
--
G
----
M
-
P
A
--
T
--------
K
-
D
L
A
A
L
D
R
V
-------
K
I
H
S
Y
N
K
E
P
-
R
K
-
G
R
K
V
G
H
L
N
L
N
L
N
D
E
T
D
E
Y
Q
L
L
-
Q
V
K
K
L
I
------------
22
PsiBlast_CBE
88.37
43%
-8
- C1 -
-
4DLK
1
?
B:
[9-355]
--
K
T
I
G
I
I
G
G
G
Q
L
G
R
M
M
A
L
A
A
K
E
M
G
Y
K
I
A
V
L
D
P
T
K
N
S
P
C
A
Q
V
A
---
D
IEI
V
A
---
S
Y
D
--
D
L
K
------
A
I
Q
H
L
A
E
I
S
D
V
V
T
Y
E
F
E
N
I
D
Y
R
C
L
Q
W
L
E
K
H
-
A
Y
L
P
Q
G
S
Q
L
L
S
K
T
Q
N
R
F
T
E
K
N
A
I
E
K
A
G
L
P
V
A
T
Y
R
L
V
Q
N
Q
E
Q
L
T
---
E
A
I
A
E
L
S
Y
P
S
V
L
K
T
T
T
G
-
G
-
Y
-
D
G
K
G
Q
V
V
L
R
S
E
A
D
V
D
E
A
-
R
K
L
A
N
-
A
-
A
E
C
I
L
E
K
W
V
P
F
E
-
K
E
V
S
V
I
V
I
R
S
V
--
S
G
E
T
K
V
F
P
V
A
E
N
I
H
V
N
N
I
L
H
E
S
I
V
P
A
R
-
I
-
T
-
E
E
L
S
Q
K
A
I
A
Y
A
K
V
L
A
D
E
L
E
L
V
G
T
L
A
V
E
M
F
A
-
T
A
-
D
-
G
E
I
Y
I
N
E
L
A
P
R
P
H
N
S
G
H
Y
T
Q
D
A
C
E
T
S
Q
F
G
Q
H
I
R
A
I
C
N
L
P
L
-
G
E
T
N
-
L
L
K
P
V
V
M
V
N
I
L
G
--
E
----
H
-
I
E
GV
L
--------
R
-
Q
V
N
R
L
T
G
C
-------
Y
L
H
L
Y
G
K
E
E
A
K
A
-
Q
R
K
M
G
H
V
N
I
L
------------------------------
11
PsiBlast_PDB
87.98
43%
-10
- C1 -
-
3V4S
1
?
A:
[15-361]
--
K
T
I
G
I
I
G
G
G
Q
L
G
R
M
M
A
L
A
A
K
E
M
G
Y
K
I
A
V
L
D
P
T
K
N
S
P
C
A
Q
V
A
---
D
I
E
I
V
A
---
S
Y
D
--
D
L
K
------
A
I
Q
H
L
A
E
I
S
D
V
V
T
Y
E
F
E
N
I
D
Y
R
C
L
Q
W
L
E
K
H
-
A
Y
L
P
Q
G
S
Q
L
L
S
K
T
Q
N
R
F
T
E
K
N
A
I
E
K
A
G
L
P
V
A
T
Y
R
L
V
Q
N
Q
E
Q
L
T
---
E
A
I
A
E
L
S
Y
P
S
V
L
K
T
T
T
G
-
G
-
Y
-
D
G
K
G
Q
V
V
L
R
S
E
A
D
V
D
E
A
-
R
K
L
A
N
-
A
-
A
E
C
I
L
E
K
W
V
P
F
E
-
K
E
V
S
V
I
V
I
R
S
V
--
S
G
E
T
K
V
F
P
V
A
E
N
I
H
V
N
N
I
L
H
E
S
I
V
P
A
R
-
I
-
T
-
E
E
L
S
Q
K
A
I
A
Y
A
K
V
L
A
D
E
L
E
L
V
G
T
L
A
V
E
M
F
A
-
T
A
-
D
-
G
E
I
Y
I
N
E
L
A
P
R
P
H
N
S
G
H
Y
T
Q
D
A
C
E
T
S
Q
F
G
Q
H
I
R
A
I
C
N
L
P
L
-
G
E
T
N
-
L
L
K
P
V
V
M
V
N
I
L
G
--
E
----
H
-
I
E
G
V
L
--------
R
-
Q
V
N
R
L
T
G
C
-------
Y
L
H
L
Y
G
K
E
E
A
K
A
-
Q
R
K
M
G
H
V
N
I
L
------------------------------
74
HHSearch
87.61
38%
-6
- C1 -
-
4E4T
-
?
A:
[34-418]
P
G
A
W
L
G
M
V
G
G
G
Q
L
G
R
M
F
C
F
A
A
Q
S
M
G
Y
R
V
A
V
L
D
P
D
P
A
S
P
A
G
A
V
A
DRH
L
---
R
A
---
A
Y
D
--
D
E
A
------
A
L
A
E
L
A
G
L
C
E
A
V
S
T
E
F
E
N
V
P
A
A
S
L
D
F
L
A
R
T
-
T
F
V
A
P
A
G
R
C
V
A
V
A
Q
D
R
I
A
E
K
R
F
I
E
A
S
G
V
P
V
A
P
H
V
V
I
E
S
A
A
A
L
A
A
LD
D
A
A
L
D
A
V
L
P
G
I
L
K
T
A
-
R
L
G
-
Y
-
D
G
K
G
Q
V
R
V
S
T
A
R
E
A
R
D
A
H
A
A
L
G
G
---
V
P
C
V
L
E
K
R
L
P
-
L
--
K
Y
E
V
S
A
L
I
A
R
G
A
D
G
R
S
A
A
F
P
L
A
Q
N
V
H
H
N
G
I
L
A
L
T
I
V
P
A
P
-
A
-
A
D
T
A
R
V
E
E
A
Q
Q
A
A
V
R
I
A
D
T
L
G
Y
V
G
V
L
C
V
E
F
F
V
-
L
E
D
G
-
S
-
F
V
A
N
E
M
A
P
R
P
H
N
S
G
H
Y
T
V
D
A
C
A
T
S
Q
F
E
Q
Q
V
R
A
M
T
R
M
P
L
-
G
N
P
R
-
Q
H
S
P
A
A
M
L
N
I
L
G
--
D
VWFP
N
-
G
A
--
A
A
G
A
V
T
P
P
W
D
-
T
V
A
A
M
P
A
A
-------
H
L
H
L
Y
G
K
E
E
A
R
V
-
G
R
K
M
G
H
V
N
F
T
A
E
M
R
D
D
A
V
A
A
A
T
A
C
A
Q
L
L
R
V
P
L
--------
3
PsiBlast_PDB
87.38
41%
-7
- C1 -
-
4MA5
3
?
A:
[3-359]
----
I
G
I
I
G
A
G
Q
L
A
R
M
L
S
L
A
G
T
P
L
G
L
E
F
H
C
L
G
K
N
G
D
C
A
E
E
V
V
K
---
T
---
V
T
---
D
I
E
--
L
T
K
V
N
D
V
V
A
W
A
K
Q
F
----
D
V
I
T
F
E
N
E
N
I
S
H
E
L
I
K
A
I
N
H
E
-
V
S
V
Y
P
S
A
K
A
I
A
I
S
Q
D
R
L
L
E
K
S
F
M
Q
D
H
G
I
A
T
A
K
F
V
N
I
D
S
L
A
K
L
Q
---
S
A
V
D
D
H
G
L
P
A
I
L
K
T
R
R
F
-
G
-
Y
-
D
G
K
G
Q
F
V
I
R
S
Q
E
D
I
T
K
A
W
D
V
L
K
D
-
A
P
D
G
L
I
Y
E
A
F
V
D
F
D
-
Y
E
V
S
Q
I
C
T
A
D
L
--
K
G
N
I
A
F
Y
P
L
A
R
N
T
H
K
Q
G
I
I
V
E
S
E
A
P
F
E
-
N
-
V
--
V
L
A
E
K
A
Q
Q
I
A
K
I
L
V
K
E
F
A
Y
V
G
T
L
A
I
E
F
F
V
-
K
----
E
-
L
I
V
N
E
I
A
P
R
V
H
N
S
G
H
W
S
I
D
G
A
V
T
S
Q
F
E
N
H
V
R
A
I
A
G
L
I
L
-
G
D
T
--
T
S
R
K
T
V
M
L
N
C
I
G
--
G
----
M
-
P
A
--
T
--------
K
-
D
L
A
A
L
D
R
V
-------
K
I
H
S
Y
N
K
E
P
-
R
K
-
G
R
K
V
G
H
L
N
L
N
L
N
D
E
T
D
E
Y
Q
L
L
-
Q
V
K
K
L
I
------------
24
PsiBlast_CBE
87.19
43%
-9
- C1 -
-
3QFF
1
?
B:
[15-361]
--
K
T
I
G
I
I
G
G
G
Q
L
G
R
M
M
A
L
A
A
K
E
M
G
Y
K
I
A
V
L
D
P
T
K
N
S
P
C
A
Q
V
A
---
D
IEI
V
A
---
S
Y
D
--
D
L
K
------
A
I
Q
H
L
A
E
I
S
D
V
V
T
Y
E
F
E
N
I
D
Y
R
C
L
Q
W
L
E
K
H
-
A
Y
L
P
Q
G
S
Q
L
L
S
K
T
Q
N
R
F
T
E
K
N
A
I
E
K
A
G
L
P
V
A
T
Y
R
L
V
Q
N
Q
E
Q
L
T
---
E
A
I
A
E
L
S
Y
P
S
V
L
K
T
T
T
G
-
G
-
Y
-
D
G
K
G
Q
V
V
L
R
S
E
A
D
V
D
E
A
-
R
K
L
A
N
-
A
-
A
E
C
I
L
E
K
W
V
P
F
E
-
K
E
V
S
V
I
V
I
R
S
V
--
S
G
E
T
K
V
F
P
V
A
E
N
I
H
V
N
N
I
L
H
E
S
I
V
P
A
R
-
I
-
T
-
E
E
L
S
Q
K
A
I
A
Y
A
K
V
L
A
D
E
L
E
L
V
G
T
L
A
V
E
M
F
A
-
T
A
-
D
-
G
E
I
Y
I
N
E
L
A
P
R
P
H
N
S
G
H
Y
T
Q
D
A
C
E
T
S
Q
F
G
Q
H
I
R
A
I
C
N
L
P
L
-
G
E
T
N
-
L
L
K
P
V
V
M
V
N
I
L
G
--
E
----
H
-
I
E
GV
L
--------
R
-
Q
V
N
R
L
T
G
C
-------
Y
L
H
L
Y
G
K
E
E
A
K
A
-
Q
R
K
M
G
H
V
N
I
L
------------------------------
8
PsiBlast_PDB
87.14
43%
-13
- C1 -
-
3Q2O
-
?
A:
[15-361]
--
K
T
I
G
I
I
G
G
G
Q
L
G
R
M
M
A
L
A
A
K
E
M
G
Y
K
I
A
V
L
D
P
T
K
N
S
P
C
A
Q
V
A
---
D
I
E
I
V
A
---
S
Y
D
--
D
L
K
------
A
I
Q
H
L
A
E
I
S
D
V
V
T
Y
E
F
E
N
I
D
Y
R
C
L
Q
W
L
E
K
H
-
A
Y
L
P
Q
G
S
Q
L
L
S
K
T
Q
N
R
F
T
E
K
N
A
I
E
K
A
G
L
P
V
A
T
Y
R
L
V
Q
N
Q
E
Q
L
T
---
E
A
I
A
E
L
S
Y
P
S
V
L
K
T
T
T
G
-
G
-
Y
-
D
G
K
G
Q
V
V
L
R
S
E
A
D
V
D
E
A
-
R
K
L
A
N
-
A
-
A
E
C
I
L
E
K
W
V
P
F
E
-
K
E
V
S
V
I
V
I
R
S
V
--
S
G
E
T
K
V
F
P
V
A
E
N
I
H
V
N
N
I
L
H
E
S
I
V
P
A
R
-
I
-
T
-
E
E
L
S
Q
K
A
I
A
Y
A
K
V
L
A
D
E
L
E
L
V
G
T
L
A
V
E
M
F
A
-
T
A
-
D
-
G
E
I
Y
I
N
E
L
A
P
R
P
H
N
S
G
H
Y
T
Q
D
A
C
E
T
S
Q
F
G
Q
H
I
R
A
I
C
N
L
P
L
-
G
E
T
N
-
L
L
K
P
V
V
M
V
N
I
L
G
--
E
----
H
-
I
E
G
V
L
--------
R
-
Q
V
N
R
L
T
G
C
-------
Y
L
H
L
Y
G
K
E
E
A
K
A
-
Q
R
K
M
G
H
V
N
I
L
------------------------------
23
PsiBlast_CBE
86.89
43%
-13
- C1 -
-
3R5H
2
?
B:
[15-361]
--
K
T
I
G
I
I
G
G
G
Q
L
G
R
M
M
A
L
A
A
K
E
M
G
Y
K
I
A
V
L
D
P
T
K
N
S
P
C
A
Q
V
A
---
D
IEI
V
A
---
S
Y
D
--
D
L
K
------
A
I
Q
H
L
A
E
I
S
D
V
V
T
Y
E
F
E
N
I
D
Y
R
C
L
Q
W
L
E
K
H
-
A
Y
L
P
Q
G
S
Q
L
L
S
K
T
Q
N
R
F
T
E
K
N
A
I
E
K
A
G
L
P
V
A
T
Y
R
L
V
Q
N
Q
E
Q
L
T
---
E
A
I
A
E
L
S
Y
P
S
V
L
K
T
T
T
G
-
G
-
Y
-
D
G
K
G
Q
V
V
L
R
S
E
A
D
V
D
E
A
-
R
K
L
A
N
-
A
-
A
E
C
I
L
E
K
W
V
P
F
E
-
K
E
V
S
V
I
V
I
R
S
V
--
S
G
E
T
K
V
F
P
V
A
E
N
I
H
V
N
N
I
L
H
E
S
I
V
P
A
R
-
I
-
T
-
E
E
L
S
Q
K
A
I
A
Y
A
K
V
L
A
D
E
L
E
L
V
G
T
L
A
V
E
M
F
A
-
T
A
-
D
-
G
E
I
Y
I
N
E
L
A
P
R
P
H
N
S
G
H
Y
T
Q
D
A
C
E
T
S
Q
F
G
Q
H
I
R
A
I
C
N
L
P
L
-
G
E
T
N
-
L
L
K
P
V
V
M
V
N
I
L
G
--
E
----
H
-
I
E
GV
L
--------
R
-
Q
V
N
R
L
T
G
C
-------
Y
L
H
L
Y
G
K
E
E
A
K
A
-
Q
R
K
M
G
H
V
N
I
L
------------------------------
1
PsiBlast_PDB
86.64
46%
2
- C1 -
-
3AW8
1
?
A:
[12-362]
--------------
R
M
L
A
L
A
G
Y
P
L
G
L
S
F
R
F
L
D
P
S
P
E
A
C
A
G
Q
V
G
---
E
---
L
V
---
V
G
E
FL
D
E
G
------
A
L
L
R
F
A
E
G
L
A
L
V
T
Y
E
F
E
N
V
P
V
E
A
A
R
R
L
E
G
R
-
L
P
L
Y
P
P
A
K
A
L
E
V
A
Q
D
R
L
R
E
K
T
F
F
Q
G
L
G
V
P
T
P
P
F
H
P
V
D
G
P
E
D
L
E
---
E
G
L
K
R
V
G
L
P
A
L
L
K
T
R
R
G
---------
Q
A
L
V
R
T
E
E
E
A
L
E
A
L
K
A
L
G
--
G
-
R
G
L
I
L
E
G
F
V
P
F
D
-
R
E
V
S
L
L
A
V
R
G
R
--
T
G
E
V
A
F
Y
P
L
V
E
N
R
H
W
G
G
I
L
R
L
S
L
A
P
A
P
-
G
A
S
-
E
A
L
Q
K
K
A
E
A
Y
A
L
R
A
M
E
A
L
D
Y
V
G
V
L
A
L
E
F
F
Q
-
V
G
-
E
-
E
-
L
L
F
N
E
M
A
P
R
V
H
N
S
G
H
W
T
I
E
G
A
E
T
S
Q
F
E
N
H
L
R
A
V
L
G
L
P
L
-
G
S
T
A
-
P
R
G
Q
S
A
M
V
N
L
I
G
--
E
----
K
-
P
P
--
F
--------
A
-
E
V
L
K
V
E
G
A
-------
H
L
H
W
Y
G
K
A
V
-
R
P
-
G
R
K
V
G
H
I
T
L
R
R
D
G
L
K
A
L
E
E
G
L
A
R
L
S
R
L
V
S
E
----------
2
PsiBlast_PDB
86.54
41%
-7
- C1 -
-
5JQW
1
?
A:
[6-362]
----
I
G
I
I
G
A
G
Q
L
A
R
M
L
S
L
A
G
T
P
L
G
L
E
F
H
C
L
G
K
N
G
D
C
A
E
E
V
V
K
---
T
---
V
T
---
D
I
E
--
L
T
K
V
N
D
V
V
A
W
A
K
Q
F
----
D
V
I
T
F
E
N
E
N
I
S
H
E
L
I
K
A
I
N
H
E
-
V
S
V
Y
P
S
A
K
A
I
A
I
S
Q
D
R
L
L
E
K
S
F
M
Q
D
H
G
I
A
T
A
K
F
V
N
I
D
S
L
A
K
L
Q
---
S
A
V
D
D
H
G
L
P
A
I
L
K
T
R
R
F
-
G
-
Y
-
D
G
K
G
Q
F
V
I
R
S
Q
E
D
I
T
K
A
W
D
V
L
K
D
-
A
P
D
G
L
I
Y
E
A
F
V
D
F
D
-
Y
E
V
S
Q
I
C
T
A
D
L
--
K
G
N
I
A
F
Y
P
L
A
R
N
T
H
K
Q
G
I
I
V
E
S
E
A
P
F
E
-
N
-
V
--
V
L
A
E
K
A
Q
Q
I
A
K
I
L
V
K
E
F
A
Y
V
G
T
L
A
I
E
F
F
V
-
K
G
-
D
-
E
-
L
I
V
N
E
I
A
P
R
V
H
N
S
G
H
W
S
I
D
G
A
V
T
S
Q
F
E
N
H
V
R
A
I
A
G
L
I
L
-
G
D
T
--
T
S
R
K
T
V
M
L
N
C
I
G
--
G
----
M
-
P
A
--
T
--------
K
-
D
L
A
A
L
D
R
V
-------
K
I
H
S
Y
N
K
E
P
-
R
K
-
G
R
K
V
G
H
L
N
L
N
L
N
D
E
T
D
E
Y
Q
L
L
-
Q
V
K
K
L
I
------------
69
HHSearch
86.47
40%
7
- C1 -
-
3Q2O
-
?
B:
[13-383]
P
G
K
T
I
G
I
I
G
G
G
Q
L
G
R
M
M
A
L
A
A
K
E
M
G
Y
K
I
A
V
L
D
P
T
K
N
S
P
C
A
Q
V
A
DIE
I
---
V
A
---
S
Y
D
--
D
L
K
------
A
I
Q
H
L
A
E
I
S
D
V
V
T
Y
E
F
E
N
I
D
Y
R
C
L
Q
W
L
E
K
H
A
Y
L
P
-
Q
G
S
Q
L
L
S
K
T
Q
N
R
F
T
E
K
N
A
I
E
K
A
G
L
P
V
A
T
Y
R
L
V
Q
N
Q
E
Q
L
T
---
E
A
I
A
E
L
S
Y
P
S
V
L
K
T
T
-
T
-
G
-
G
Y
D
G
K
G
Q
V
V
L
R
S
E
A
D
V
D
E
A
R
K
L
A
N
A
---
A
E
C
I
L
E
K
W
V
P
-
F
E
K
E
V
S
V
I
V
I
R
S
V
--
S
G
E
T
K
V
F
P
V
A
E
N
I
H
V
N
N
I
L
H
E
S
I
V
P
A
R
-
I
-
T
-
E
E
L
S
Q
K
A
I
A
Y
A
K
V
L
A
D
E
L
E
L
V
G
T
L
A
V
E
M
F
A
-
T
A
-
D
G
E
-
I
Y
I
N
E
L
A
P
R
P
H
N
S
G
H
Y
T
Q
D
A
C
E
T
S
Q
F
G
Q
H
I
R
A
I
C
N
L
P
L
-
G
E
T
N
-
L
L
K
P
V
V
M
V
N
I
L
G
EH
I
----
E
-
G
V
--
L
--------
R
-
Q
V
N
R
L
T
G
C
-------
Y
L
H
L
Y
G
K
E
E
A
K
A
-
Q
R
K
M
G
H
V
N
I
L
N
D
N
I
E
V
A
L
E
K
A
K
S
L
H
I
W
D
H
Q
E
Q
--------
73
HHSearch
86.14
40%
7
* C1 *
-
4DLK
1
?
B:
[7-374]
P
G
K
T
I
G
I
I
G
G
G
Q
L
G
R
M
M
A
L
A
A
K
E
M
G
Y
K
I
A
V
L
D
P
T
K
N
S
P
C
A
Q
V
A
DIE
I
---
V
A
---
S
Y
D
--
D
L
K
------
A
I
Q
H
L
A
E
I
S
D
V
V
T
Y
E
F
E
N
I
D
Y
R
C
L
Q
W
L
E
K
H
A
Y
L
P
-
Q
G
S
Q
L
L
S
K
T
Q
N
R
F
T
E
K
N
A
I
E
K
A
G
L
P
V
A
T
Y
R
L
V
Q
N
Q
E
Q
L
T
---
E
A
I
A
E
L
S
Y
P
S
V
L
K
T
T
-
T
-
G
-
G
Y
D
G
K
G
Q
V
V
L
R
S
E
A
D
V
D
E
A
R
K
L
A
N
A
---
A
E
C
I
L
E
K
W
V
P
-
F
E
K
E
V
S
V
I
V
I
R
S
V
--
S
G
E
T
K
V
F
P
V
A
E
N
I
H
V
N
N
I
L
H
E
S
I
V
P
A
R
-
I
-
T
-
E
E
L
S
Q
K
A
I
A
Y
A
K
V
L
A
D
E
L
E
L
V
G
T
L
A
V
E
M
F
A
-
T
A
-
D
G
E
-
I
Y
I
N
E
L
A
P
R
P
H
N
S
G
H
Y
T
Q
D
A
C
E
T
S
Q
F
G
Q
H
I
R
A
I
C
N
L
P
L
-
G
E
T
N
-
L
L
K
P
V
V
M
V
N
I
L
G
EH
I
----
E
-
G
V
--
L
--------
R
-
Q
V
N
R
L
T
G
C
-------
Y
L
H
L
Y
G
K
E
E
A
K
A
-
Q
R
K
M
G
H
V
N
I
L
N
D
N
I
E
V
A
L
E
K
A
K
S
L
H
I
W
D
H
-----------
21
PsiBlast_CBE
85.37
46%
-2
- C1 -
-
3AW8
1
?
B:
[12-362]
--------------
R
M
L
A
L
A
G
Y
P
L
G
L
S
F
R
F
L
D
P
S
P
E
A
C
A
G
Q
V
G
---
E
---
L
V
---
V
G
E
FL
D
E
G
------
A
L
L
R
F
A
E
G
L
A
L
V
T
Y
E
F
E
N
V
P
V
E
A
A
R
R
L
E
G
R
-
L
P
L
Y
P
P
A
K
A
L
E
V
A
Q
D
R
L
R
E
K
T
F
F
Q
G
L
G
V
P
T
P
P
F
H
P
V
D
G
P
E
D
L
E
---
E
G
L
K
R
V
G
L
P
A
L
L
K
T
R
R
G
---------
Q
A
L
V
R
T
E
E
E
A
L
E
A
L
K
A
L
G
--
G
-
R
G
L
I
L
E
G
F
V
P
F
D
-
R
E
V
S
L
L
A
V
R
G
R
--
T
G
E
V
A
F
Y
P
L
V
E
N
R
H
W
G
G
I
L
R
L
S
L
A
P
A
P
-
G
A
S
-
E
A
L
Q
K
K
A
E
A
Y
A
L
R
A
M
E
A
L
D
Y
V
G
V
L
A
L
E
F
F
Q
-
V
G
-
E
-
E
-
L
L
F
N
E
M
A
P
R
V
H
N
S
G
H
W
T
I
E
G
A
E
T
S
Q
F
E
N
H
L
R
A
V
L
G
L
P
L
-
G
S
T
A
-
P
R
G
Q
S
A
M
V
N
L
I
G
--
E
----
K
-
P
P
--
F
--------
A
-
E
V
L
K
V
E
G
A
-------
H
L
H
W
Y
G
K
A
V
-
R
P
-
G
R
K
V
G
H
I
T
L
R
R
D
G
L
K
A
L
E
E
G
L
A
R
L
S
R
L
V
S
E
----------
72
HHSearch
79.13
34%
20
- C1 -
-
3ORQ
2
?
A:
[11-374]
F
G
A
T
I
G
I
I
G
G
G
Q
L
G
K
M
M
A
Q
S
A
Q
K
M
G
Y
K
V
V
V
L
D
P
S
E
D
C
P
C
R
Y
V
A
H
E
F
I
---
Q
A
---
K
Y
D
--
D
E
K
------
A
L
N
Q
L
G
Q
K
C
D
V
I
T
Y
E
F
E
N
I
S
A
Q
Q
L
K
L
L
C
E
K
Y
N
I
P
-
Q
G
Y
Q
A
I
Q
L
L
Q
D
R
L
T
E
K
E
T
L
K
S
A
G
T
K
V
V
P
F
I
S
V
K
E
S
T
D
I
D
---
K
A
I
E
T
L
G
Y
P
F
I
V
K
T
R
-
F
-
G
G
Y
-
D
G
K
G
Q
V
L
I
N
N
E
K
D
L
Q
E
G
F
K
L
I
E
T
---
S
E
C
V
A
E
K
Y
L
N
I
K
-
K
E
V
S
L
T
V
T
R
G
N
--
N
N
Q
I
T
F
F
P
L
Q
E
N
E
H
R
N
Q
I
L
F
K
T
I
V
P
A
R
-
I
-
D
---
K
T
A
E
A
K
E
Q
V
N
K
I
I
Q
S
I
H
F
I
G
T
F
T
V
E
F
F
I
-
D
S
-
N
N
Q
-
L
Y
V
N
E
I
A
P
R
P
H
N
S
G
H
Y
S
I
E
A
C
D
Y
S
Q
F
D
T
H
I
L
A
V
T
G
Q
S
L
-
P
N
S
I
E
L
L
K
P
A
V
M
M
N
L
L
G
--
K
----
D
L
D
L
--
L
--------
E
N
E
F
N
E
H
P
E
W
-------
H
L
H
I
Y
G
K
S
E
R
K
D
-
S
R
K
M
G
H
M
T
V
L
T
N
D
V
N
Q
T
E
Q
D
M
Y
A
K
F
E
--------------
17
PsiBlast_PDB
69.73
33%
22
- C1 -
-
3ORQ
2
?
A:
[22-364]
-----------
Q
L
G
K
M
M
A
Q
S
A
Q
K
M
G
Y
K
V
V
V
L
D
P
S
E
D
C
P
C
R
Y
V
A
---
H
---
E
F
I
Q
A
K
Y
D
--
D
E
K
------
A
L
N
Q
L
G
Q
K
C
D
V
I
T
Y
E
F
E
N
I
S
A
Q
Q
L
K
L
L
C
E
K
-
Y
N
I
P
Q
G
Y
Q
A
I
Q
L
L
Q
D
R
L
T
E
K
E
T
L
K
S
A
G
T
K
V
V
P
F
I
S
V
K
E
S
T
D
I
D
---
K
A
I
E
T
L
G
Y
P
F
I
V
K
T
R
F
G
-
G
-
Y
-
D
G
K
G
Q
V
L
I
N
N
E
K
D
L
Q
E
G
F
-
K
L
I
E
-
T
-
S
E
C
V
A
E
K
Y
L
N
I
K
-
K
E
V
S
L
T
V
T
R
G
N
--
N
N
Q
I
T
F
F
P
L
Q
E
N
E
H
R
N
Q
I
L
F
K
T
I
V
P
A
R
-
I
-
D
-
K
T
A
E
--
A
K
E
Q
V
N
K
I
I
Q
S
I
H
F
I
G
T
F
T
V
E
F
F
I
D
S
N
-
N
-
Q
-
L
Y
V
N
E
I
A
P
R
P
H
N
S
G
H
Y
S
I
E
A
C
D
Y
S
Q
F
D
T
H
I
L
A
V
T
G
Q
S
L
P
N
S
I
E
-
L
L
K
P
A
V
M
M
N
L
L
G
----------------------
K
-
D
L
D
L
L
E
N
E
FNEHPEW
H
L
H
I
Y
G
K
S
E
-
R
K
D
S
R
K
M
G
H
M
T
V
L
T
N
D
V
N
Q
------------------------