@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VQ52: (2017-11-25 )
MSGLLFVVSAASGTGKTSLVKALLDRVSNLHVSVSHTTRGQRPGELDGVHYHFTTKDEFLDQVNQGGFIEYAEVFGNYYGTSQATVKQQLAQGHDVLLEIDWQGAEQVRKLFPESKQIFILPPTQFDLRQRLSNRGTDSVEVIEHRLSCAVEDMQHYVNFDYIIINDDFNKALHELEAVITANRLVLSQQAKRHQNLIQDLITPQPKQE
Atome Classification :
(29 SA)
.........10........20...-..--..-.30........40........50........60........70.......--.--80........90........100.......110.-.-.....120.......130.......140.......150...--....160.......170.......180.......190.......200.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MS
G
L
L
F
V
V
SAASGT
G
K
T
S
L
V
K
A
L
L
-
D
R
--VS-N
L
H
V
S
V
SHTTRGQRPGELD
G
V
H
Y
H
FT
T
K
D
E
F
L
D
Q
VNQGG
F
I
E
Y
A
E
V
F
G
NY--Y--GT
S
Q
A
T
V
K
Q
Q
L
AQG
H
D
V
L
L
E
I
DWQ
G
A
E
Q
V
R
K
LFP-E-S
K
Q
I
F
I
LPP
T
Q
F
D
L
R
Q
R
L
SNRGT
D
S
V
E
V
I
E
H
R
L
S
C
A
V
E
D
M
Q
--
H
YVNF
D
Y
I
I
IND
D
F
N
K
A
L
H
E
L
E
A
V
I
T
A
N
R
L
V
L
S
Q
Q
A
K
R
H
Q
N
L
I
Q
D
LITPQPKQE
7
PsiBlast_PDB
89.49
46%
-110
- C3 -
-
3TR0
1
KGUA_COXBU
A:
[9-205]
----
L
F
I
I
S
A
P
S
G
A
G
K
T
S
L
V
R
A
L
V
-
K
A
--
L
A
-
E
I
K
I
S
I
S
H
T
T
R
P
K
R
P
G
D
Q
E
G
V
D
Y
F
F
I
D
E
T
R
F
Q
A
M
V
K
E
G
A
F
L
E
H
A
T
I
Y
E
R
H
--
Y
--
G
T
E
K
D
W
V
L
R
Q
L
K
A
G
R
D
V
L
L
E
I
D
W
Q
G
A
R
Q
I
R
E
L
F
P
-
P
-
A
L
S
I
F
I
L
P
P
S
I
E
A
L
R
E
R
L
I
K
R
R
Q
D
D
T
A
I
I
E
Q
R
L
A
L
A
R
E
E
M
A
--
H
Y
K
E
F
D
Y
L
V
V
N
D
N
F
D
Q
A
V
Q
N
L
I
H
I
I
S
A
E
R
L
Q
R
D
V
Q
E
K
K
L
S
R
L
L
A
E
L
--------
39
HHSearch
87.98
47%
-99
- C3 -
-
3TR0
1
KGUA_COXBU
A:
[6-202]
-
K
A
N
L
F
I
I
S
A
P
S
G
A
G
K
T
S
L
V
R
A
L
V
-
K
A
--
L
A
-
E
I
K
I
S
I
S
H
T
T
R
P
K
R
P
G
D
Q
E
G
V
D
Y
F
F
I
D
E
T
R
F
Q
A
M
V
K
E
G
A
F
L
E
H
A
T
I
Y
E
R
H
--
Y
--
G
T
E
K
D
W
V
L
R
Q
L
K
A
G
R
D
V
L
L
E
I
D
W
Q
G
A
R
Q
I
R
E
L
F
P
-
P
-
A
L
S
I
F
I
L
P
P
S
I
E
A
L
R
E
R
L
I
K
R
R
Q
D
D
T
A
I
I
E
Q
R
L
A
L
A
R
E
E
M
A
--
H
Y
K
E
F
D
Y
L
V
V
N
D
N
F
D
Q
A
V
Q
N
L
I
H
I
I
S
A
E
R
L
Q
R
D
V
Q
E
K
K
L
S
R
L
L
-----------
5
PsiBlast_PDB
79.28
51%
10
- C3 -
-
2F3T
1
KGUA_ECOLI
A:
[4-206]
--
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
QP
L
Y
-
D
T
Q
V
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
Y
--
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
P
-
H
-
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
S
--
H
Y
A
E
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
K
Q
R
H
D
A
L
I
S
K
L
L
A
------
22
PsiBlast_CBE
77.41
51%
12
- C3 -
-
2F3T
1
KGUA_ECOLI
E:
[4-205]
--
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
QP
L
Y
-
D
T
Q
V
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
Y
--
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
P
-
H
-
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
S
--
H
Y
A
E
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
K
Q
R
H
D
A
L
I
S
K
L
L
-------
21
PsiBlast_CBE
77.40
51%
12
- C3 -
-
2F3T
1
KGUA_ECOLI
F:
[4-206]
--
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
QP
L
Y
-
D
T
Q
V
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
Y
--
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
P
-
H
-
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
S
--
H
Y
A
E
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
K
Q
R
H
D
A
L
I
S
K
L
L
A
------
6
PsiBlast_PDB
77.04
51%
14
- C3 -
-
1S96
-
KGUA_ECOLI
A:
[16-218]
--
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
QP
L
Y
-
D
T
Q
V
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
Y
--
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
P
-
H
-
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
S
--
H
Y
A
E
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
K
Q
R
H
D
A
L
I
S
K
L
L
A
------
3
PsiBlast_PDB
76.67
51%
11
- C3 -
-
2ANC
-
KGUA_ECOLI
A:
[4-206]
--
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
QP
L
Y
-
D
T
Q
V
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
Y
--
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
P
-
H
-
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
S
--
H
Y
A
E
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
K
Q
R
H
D
A
L
I
S
K
L
L
A
------
4
PsiBlast_PDB
76.57
51%
13
- C3 -
-
2F3R
1
KGUA_ECOLI
A:
[4-206]
--
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
Q
P
L
Y
-
D
T
Q
V
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
Y
--
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
P
-
H
-
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
----
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
S
--
H
Y
A
E
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
K
Q
R
H
D
A
L
I
S
K
L
L
A
------
1
PsiBlast_PDB
76.57
51%
18
- C3 -
-
2AN9
2
KGUA_ECOLI
A:
[4-206]
--
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
Q
P
L
Y
-
D
T
Q
V
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
Y
--
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
P
-
H
-
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
S
--
H
Y
A
E
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
K
Q
R
H
D
A
L
I
S
K
L
L
A
------
2
PsiBlast_PDB
76.56
51%
22
- C3 -
-
2ANB
1
KGUA_ECOLI
A:
[4-206]
--
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
QP
L
Y
-
D
T
Q
V
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
Y
--
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
P
-
H
-
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
S
--
H
Y
A
E
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
K
Q
R
H
D
A
L
I
S
K
L
L
A
------
23
PsiBlast_CBE
75.25
51%
9
- C3 -
-
2F3T
1
KGUA_ECOLI
B:
[4-206]
--
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
QP
L
Y
-
D
T
Q
V
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
Y
--
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
P
-
H
-
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
---
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
S
--
H
Y
A
E
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
K
Q
R
H
D
A
L
I
S
K
L
L
A
------
25
PsiBlast_CBE
73.96
51%
15
- C3 -
-
2AN9
2
KGUA_ECOLI
B:
[4-206]
--
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
QP
L
Y
-
D
T
Q
V
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
Y
--
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
P
-
H
-
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
R
G
Q
D
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
S
--
H
Y
A
E
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
K
Q
R
H
D
A
L
I
S
K
L
L
A
------
24
PsiBlast_CBE
73.87
51%
17
- C3 -
-
2F3R
1
KGUA_ECOLI
B:
[4-204]
--
G
T
L
Y
I
V
S
A
P
S
G
A
G
K
S
S
L
I
Q
A
L
L
-
K
T
QP
L
Y
-
D
T
Q
V
S
V
S
H
T
T
R
Q
P
R
P
G
E
V
H
G
E
H
Y
F
F
V
N
H
D
E
F
K
E
M
I
S
R
D
A
F
L
E
H
A
E
V
F
G
N
Y
--
Y
--
G
T
S
R
E
A
I
E
Q
V
L
A
T
G
V
D
V
F
L
D
I
D
W
Q
G
A
Q
Q
I
R
Q
K
M
P
-
H
-
A
R
S
I
F
I
L
P
P
S
K
I
E
L
D
R
R
L
R
G
----
S
E
E
V
I
A
K
R
M
A
Q
A
V
A
E
M
S
--
H
Y
A
E
Y
D
Y
L
I
V
N
D
D
F
D
T
A
L
T
D
L
K
T
I
I
R
A
E
R
L
R
M
S
R
Q
K
Q
R
H
D
A
L
I
S
K
L
--------
47
HHSearch
72.95
38%
-19
- C3 -
-
1ZNY
1
KGUA_MYCTU
A:
[19-201]
-
V
G
R
V
V
V
L
S
G
P
S
A
V
G
K
S
T
V
V
R
C
L
R
-
E
R
--
I
P
-
N
L
H
F
S
V
S
A
T
T
R
A
P
R
P
G
E
V
D
G
V
D
Y
H
F
I
D
P
T
R
F
Q
Q
L
I
D
Q
G
E
L
L
E
W
A
E
I
H
G
G
L
H
R
S
--
G
T
L
A
Q
P
V
R
A
A
A
A
T
G
V
P
V
L
I
E
V
D
L
A
G
A
R
A
I
K
K
T
M
P
-
E
-
A
V
T
V
F
L
A
P
P
S
W
Q
D
L
Q
A
R
L
I
G
R
G
T
E
T
A
D
V
I
Q
R
R
L
D
T
A
R
I
E
L
A
--
A
Q
G
D
F
D
K
V
V
V
N
R
R
L
E
S
A
C
A
E
L
V
S
L
L
V
G
---------------------------
48
HHSearch
72.01
38%
-23
- C3 -
-
1ZNW
-
KGUA_MYCTU
A:
[20-201]
-
V
G
R
V
V
V
L
S
G
P
S
A
V
G
K
S
T
V
V
R
C
L
R
-
E
R
--
I
P
-
N
L
H
F
S
V
S
A
T
T
R
A
P
R
P
G
E
V
D
G
V
D
Y
H
F
I
D
P
T
R
F
Q
Q
L
I
D
Q
G
E
L
L
E
W
A
E
I
H
G
G
L
H
R
S
--
G
T
L
A
Q
P
V
R
A
A
A
A
T
G
V
P
V
L
I
E
V
D
L
A
G
A
R
A
I
K
K
T
M
P
-
E
-
A
V
T
V
F
L
A
P
P
S
W
Q
D
L
Q
A
R
L
I
G
R
G
T
E
T
A
D
V
I
Q
R
R
L
D
T
A
R
I
E
L
A
--
A
Q
G
D
F
D
K
V
V
V
N
R
R
L
E
S
A
C
A
E
L
V
S
L
L
V
----------------------------
11
PsiBlast_PDB
71.21
38%
-24
- C3 -
-
1ZNW
-
KGUA_MYCTU
A:
[21-201]
--
G
R
V
V
V
L
S
G
P
S
A
V
G
K
S
T
V
V
R
C
L
R
-
E
R
--
I
P
-
N
L
H
F
S
V
S
A
T
T
R
A
P
R
P
G
E
V
D
G
V
D
Y
H
F
I
D
P
T
R
F
Q
Q
L
I
D
Q
G
E
L
L
E
W
A
E
I
H
G
G
L
--
H
R
S
G
T
L
A
Q
P
V
R
A
A
A
A
T
G
V
P
V
L
I
E
V
D
L
A
G
A
R
A
I
K
K
T
M
P
-
E
-
A
V
T
V
F
L
A
P
P
S
W
Q
D
L
Q
A
R
L
I
G
R
G
T
E
T
A
D
V
I
Q
R
R
L
D
T
A
R
I
E
L
A
--
A
Q
G
D
F
D
K
V
V
V
N
R
R
L
E
S
A
C
A
E
L
V
S
L
L
V
----------------------------
13
PsiBlast_PDB
71.13
38%
-21
- C3 -
-
1ZNY
1
KGUA_MYCTU
A:
[20-201]
--
G
R
V
V
V
L
S
G
P
S
A
V
G
K
S
T
V
V
R
C
L
R
-
E
R
--
I
P
-
N
L
H
F
S
V
S
A
T
T
R
A
P
R
P
G
E
V
D
G
V
D
Y
H
F
I
D
P
T
R
F
Q
Q
L
I
D
Q
G
E
L
L
E
W
A
E
I
H
G
G
L
--
H
R
S
G
T
L
A
Q
P
V
R
A
A
A
A
T
G
V
P
V
L
I
E
V
D
L
A
G
A
R
A
I
K
K
T
M
P
-
E
-
A
V
T
V
F
L
A
P
P
S
W
Q
D
L
Q
A
R
L
I
G
R
G
T
E
T
A
D
V
I
Q
R
R
L
D
T
A
R
I
E
L
A
--
A
Q
G
D
F
D
K
V
V
V
N
R
R
L
E
S
A
C
A
E
L
V
S
L
L
V
G
---------------------------
12
PsiBlast_PDB
70.20
38%
-22
- C3 -
-
1ZNX
1
KGUA_MYCTU
A:
[20-200]
--
G
R
V
V
V
L
S
G
P
S
A
V
G
K
S
T
V
V
R
C
L
R
-
E
R
--
I
P
-
N
L
H
F
S
V
S
A
T
T
R
A
P
R
P
G
E
V
D
G
V
D
Y
H
F
I
D
P
T
R
F
Q
Q
L
I
D
Q
G
E
L
L
E
W
A
E
I
H
G
G
L
--
H
R
S
G
T
L
A
Q
P
V
R
A
A
A
A
T
G
V
P
V
L
I
E
V
D
L
A
G
A
R
A
I
K
K
T
M
P
-
E
-
A
V
T
V
F
L
A
P
P
S
W
Q
D
L
Q
A
R
L
I
G
R
G
T
E
T
A
D
V
I
Q
R
R
L
D
T
A
R
I
E
L
A
--
A
Q
G
D
F
D
K
V
V
V
N
R
R
L
E
S
A
C
A
E
L
V
S
L
L
V
----------------------------
15
PsiBlast_PDB
70.02
37%
-26
- C3 -
-
1Z8F
2
KGUA_MYCTU
A:
[23-204]
--
G
R
V
V
V
L
S
G
P
S
A
V
G
K
S
T
V
V
R
C
L
R
-
E
R
--
I
P
-
N
L
H
F
S
V
S
A
T
T
R
C
P
R
P
G
E
V
D
G
V
D
Y
H
F
I
D
P
T
R
F
Q
Q
L
I
D
Q
G
E
L
L
E
W
A
E
I
H
G
G
L
--
H
R
S
G
T
L
A
Q
P
V
R
A
A
A
A
T
G
V
P
V
L
I
E
V
D
L
A
G
A
R
A
I
K
K
T
M
P
-
E
-
A
V
T
V
F
L
A
P
P
S
W
Q
D
L
Q
A
R
L
I
G
R
G
C
E
T
A
D
V
I
Q
R
R
L
D
T
A
R
I
E
L
A
--
A
Q
G
D
F
D
K
V
V
V
N
R
R
L
E
S
A
C
A
E
L
V
S
L
L
V
G
---------------------------
20
PsiBlast_PDB
69.42
38%
-54
- C3 -
-
3TAU
-
KGUA_LISMO
A:
[8-204]
--
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
E
A
V
F
K
D
P
--
E
T
-
S
F
D
Y
S
I
S
M
T
T
R
L
P
R
E
G
E
Q
D
G
V
D
Y
Y
F
R
S
R
E
V
F
E
Q
A
I
K
D
G
K
M
L
E
Y
A
E
Y
V
G
N
Y
--
Y
--
G
T
P
L
E
Y
V
E
E
K
L
A
A
G
V
D
I
F
L
E
I
E
V
Q
G
A
M
Q
V
R
K
A
M
P
-
E
-
G
I
F
I
F
L
T
P
P
D
L
S
E
L
K
N
R
-------
S
M
E
V
V
E
E
R
M
E
T
A
K
K
E
I
E
--
M
M
A
S
Y
D
Y
A
V
V
N
D
V
V
A
N
A
V
Q
K
I
K
G
I
V
E
T
E
H
L
K
T
E
R
V
I
H
R
Y
K
K
M
L
-----------
30
PsiBlast_CBE
67.28
40%
-44
- C3 -
-
2J41
1
KGUA_STAAC
C:
[5-197]
-
K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
E
D
P
--
S
T
-
S
Y
K
Y
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
Y
--
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
-
D
-
A
L
F
I
F
L
A
P
P
S
-------------------
Q
S
R
I
N
E
A
R
K
E
V
E
--
M
M
N
L
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
V
E
A
K
----------------
28
PsiBlast_CBE
67.05
40%
-40
- C3 -
-
4QRH
1
?
B:
[8-205]
-
K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
E
D
P
--
S
T
-
S
Y
K
Y
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
Y
--
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
-
D
-
A
L
F
I
F
L
A
P
P
S
L
E
H
L
-------------------
N
E
A
R
K
E
V
E
--
M
M
N
L
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
V
E
A
K
Y
R
K
M
I
-----------
26
PsiBlast_CBE
66.80
40%
-46
- C3 -
-
4QRH
4
?
D:
[8-203]
-
K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
E
D
P
--
S
T
-
S
Y
K
Y
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
Y
--
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
-
D
-
A
L
F
I
F
L
A
P
P
S
L
E
H
L
--------------
I
Q
S
R
I
N
E
A
R
K
E
V
E
--
M
M
N
L
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
V
E
A
K
Y
R
K
-------------
27
PsiBlast_CBE
66.73
40%
-40
- C3 -
-
4QRH
1
?
C:
[8-205]
-
K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
E
D
P
--
S
T
-
S
Y
K
Y
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
Y
--
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
-
D
-
A
L
F
I
F
L
A
P
P
S
L
E
H
L
------------------
I
N
E
A
R
K
E
V
E
--
M
M
N
L
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
V
E
A
K
Y
R
K
M
I
-----------
38
HHSearch
66.59
42%
-38
- C3 -
-
4QRH
1
?
B:
[7-196]
E
K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
-
E
D
--
P
S
T
S
Y
K
Y
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
Y
--
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
-
D
-
A
L
F
I
F
L
A
P
P
S
L
E
H
L
-------------------
N
E
A
R
K
E
V
E
--
M
M
N
L
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
--------------------
37
HHSearch
66.59
42%
-39
- C3 -
-
4QRH
1
?
C:
[7-196]
E
K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
-
E
D
--
P
S
T
S
Y
K
Y
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
Y
--
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
-
D
-
A
L
F
I
F
L
A
P
P
S
L
E
H
L
------------------
I
N
E
A
R
K
E
V
E
--
M
M
N
L
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
--------------------
29
PsiBlast_CBE
66.20
40%
-46
- C3 -
-
2J41
1
KGUA_STAAC
D:
[5-202]
-
K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
E
D
P
--
S
T
-
S
Y
K
Y
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
Y
--
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
-
D
-
A
L
F
I
F
L
A
P
P
S
------------------------
E
A
R
K
E
V
E
--
M
M
N
L
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
V
E
A
K
Y
R
K
M
I
-----------
31
PsiBlast_CBE
63.43
40%
-41
- C3 -
-
2J41
1
KGUA_STAAC
B:
[5-202]
-
K
G
L
L
I
V
L
S
G
P
S
G
V
G
K
G
T
V
R
K
R
I
F
E
D
P
--
S
T
-
S
Y
K
Y
S
I
S
M
T
T
R
Q
M
R
E
G
E
V
D
G
V
D
Y
F
F
K
T
R
D
A
F
E
A
L
I
K
D
D
Q
F
I
E
Y
A
E
Y
V
G
N
Y
--
Y
--
G
T
P
V
Q
Y
V
K
D
T
M
D
E
G
H
D
V
F
L
E
I
E
V
E
G
A
K
Q
V
R
K
K
F
P
-
D
-
A
L
F
I
F
L
A
P
P
S
----------------------------
E
V
E
--
M
M
N
L
Y
D
Y
V
V
V
N
D
E
V
E
L
A
K
N
R
I
Q
C
I
V
E
A
E
H
L
K
R
E
R
V
E
A
K
Y
R
K
M
I
-----------
40
HHSearch
61.74
31%
-2
- C3 -
-
2QOR
2
?
A:
[11-200]
-
R
I
P
P
L
V
V
C
G
P
S
G
V
G
K
G
T
L
I
K
K
V
L
-
S
E
--
F
P
S
R
F
R
F
S
I
S
C
T
T
R
N
K
R
E
K
E
T
N
G
V
D
Y
Y
F
V
D
K
D
D
F
E
R
K
L
K
E
G
Q
F
L
E
F
D
K
Y
A
N
N
F
--
Y
--
G
T
L
K
S
E
Y
D
L
A
V
G
E
G
K
I
C
L
F
E
M
N
I
N
G
V
K
Q
L
K
E
S
K
H
I
Q
D
G
I
Y
I
F
V
K
P
P
S
I
D
I
L
L
G
R
L
K
N
R
N
T
E
K
P
E
E
I
N
K
R
M
Q
E
L
T
R
E
M
D
E
A
D
K
V
G
F
N
Y
F
I
V
N
D
D
L
A
R
T
Y
A
E
L
R
E
Y
L
L
G
S
Y
P
Q
-----------------------