@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VVC1: (2017-12-23 )
MLDKKSVHRKTFKQEELILIKKLDLNETTVAMPENLFQLLIWTSDLAQHNHALFIQNKNELELVGENDQNKKQELTDKINFYKKNALIENQTKDFYLNKLLNQGDLAVKGYIQHPTRTQTKYAIIPYQGYDFITFATREIIEKFPIHFIDFKNEGAPQTLEDIHADTEELLSKVKDFVKSFREKYKEAVKKNKLIKEHNAAVHEIYIKIKNGEAKLIKDVAEEVPRVEETAPIQTVNSNEKPIKVIKKRKFALVKNE
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........--10-.........20........30-------.........-------40----------.....------------------....50..-----------...--...60........70.---.......80-.........90--.........100-.........-110--....-....120...-...-.130---------------.......140---..-......150.......160---.---------....--...-----------170.......180----------.........190.------......200----------------.---..------.---------..-------.210---------.......220--......---...230--------..-------------.....240-------....----.....250.....-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLD
K
K
S
V
H
R
--
K
--TFKQE
E
L
I
L
I
K
KLDLNETTV--------A
M
P
E
N
L
F
Q
L
-------
L
-----------
I
W
T
S
D
------------------
L
AQHN
H
A
L
-----------
F
I
Q--NKN
E
L
E
L
VGENDQ
N
K
K
---
Q
E
L
T
D
K
I
N
--
F
Y
K
KNALIEN---Q
T
K
D
F
Y
L
N
K
L
---LNQGD
L
A
V
K
-
G
Y
---IQHP-TRTQ
T
K
Y
A
I
I
-PYQ-GY
D
F
---------------
I
T
F
A
T
R
E
I
I
----
E
K-FP
I
H
F
I
D
FKNEGAP
Q
T
L
E
----
D
---------
I
HA
D
--
T
E
E
-----------
L
L
S
K
V
K
D
F
V
K
S
------------
F
R
E
K
Y
K
E
A
V
K
KN
K
------
L
I
K
E
HNA
A
V
----------------
H
---
E
I
------
Y
---------
I
K
-------
I
KNG---------
E
A
K
L
I
K
D
V
----
A
E
EVPR---VEETAP--------IQ-------------TVNSNE---------
K
P
I
K
----
V
I
K
KR
K
F
A
LVKNE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
65.13
17%
33
* C2 *
-
5FUB
6
?
A:
[1-337]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GDAWQ
D
D
E
Y
F
G
N
Y
G
T
L
R
L
H
L
E
M
L
S
D
K
P
--
R
--
T
E
T
Y
R
Q
V
I
L
S
N
S
A
A
L
R
E
K
V
V
L
DLGCGTG
V
I
S
L
F
C
A
L
L
AKPA
G
V
Y
A
-----------
V
E
A
S
S
------------------
M
A
E
H
T
E
E
L
-----------
V
K
Q
--
N
G
C
D
G
V
V
T
V
F
Q
E
R
A
E
N
---
L
T
L
P
T
K
V
D
--
V
L
V
S
E
W
M
G
N
C
---
L
L
F
E
Y
M
L
E
S
V
---
L
L
A
R
D
R
W
L
K
K
G
G
---
M
M
W
P
-
S
--
S
A
C
L
T
I
V
-
P
C
Q
-
A
F
S
D
---------------
Y
R
Q
K
V
E
F
W
E
----
N
P
-
Y
G
L
N
F
S
Y
L
Q
S
L
A
Q
K
E
F
L
S
K
P
K
F
S
---------
H
H
L
Q
--
P
E
D
-----------
C
L
S
T
P
A
D
V
I
T
L
DMVTIQVSDLE
R
L
K
G
E
F
T
F
T
V
E
K
S
G
------
M
F
H
G
F
T
V
W
F
----------------
S
---
A
H
------
F
Q
C
LEED
G
P
S
I
E
-------
L
N
T
G
PYSEITHWK
Q
T
L
F
M
L
D
A
----
P
V
S
V
E
E
G
D
I
I
A
G
S
I
R
--------
L
Q
R
NPIWRR
H
L
S
I
T
F
L
W
N
I
N
S
---------
T
E
V
S
----
T
V
K
T
K
C
F
P
M
W
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
49.13
16%
55
- C3 -
-
5H5V
-
FLID_ECOLI
A:
[8-375]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
A
Y
G
T
L
K
S
--
A
L
T
T
F
Q
T
A
N
T
A
L
S
K
A
D
L
F
S
A
T
S
T
--------
T
S
S
T
T
A
F
S
A
-------
T
T
A
G
N
A
I
A
G
K
Y
T
I
S
V
T
H
------------------
L
A
Q
A
Q
T
L
T
T
RTTRDDTKTA
I
A
T
--
S
D
S
K
L
T
I
Q
Q
G
G
D
K
D
P
I
---
T
I
D
I
S
A
A
N
SS
L
S
G
I
R
D
A
I
N
N
---
A
K
A
G
V
S
A
S
I
I
NVG
N
G
E
Y
R
L
S
V
T
-
S
N
DTG
L
D
N
A
M
T
L
S
V
S
G
D
D
A
L
-
Q
S
F
M
G
Y
D
A
SASSNGMEVSV
A
A
Q
N
A
Q
L
T
V
N
N
V
A
----
I
E
-
N
S
S
N
T
I
S
D
A
L
E
N
I
T
L
N
L
N
----
D
VTT
G
N
Q
T
L
T
I
T
Q
D
--
T
S
K
-----------
A
Q
T
A
I
K
D
W
V
N
A
------------
Y
N
S
L
I
D
T
F
S
S
L
T
K
ALLGD
S
T
L
R
T
I
Q
T
Q
L
K
S
M
L
S
N
TVSSSSYKTL
A
---
Q
I
------
G
---------
I
T
T
DPSDG
K
L
E
L
D
---------
A
D
K
L
T
A
A
L
----
K
K
D
A
S
G
---
V
G
A
L
I
V
GDGKKTG
I
T
T
-------------
T
I
G
S
N
L
---------
T
S
W
L
STTG
I
I
K
A
A
T
D
G
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
46.49
14%
100
- C3 -
-
4CMP
-
CAS9_STRP1
A:
[8-1367]
K
Y
S
I
G
L
D
I
G
TN
S
V
G
W
A
V
I
T
DEY
K
V
P
S
K
K
F
K
V
LGNTDRH
S
I
K
K
N
L
I
G
A
L
L
F
D
SGET
A
E
A
T
R
L
KRT
A
R
R
R
Y
T
R
R
K
N
R
I
C
Y
L
Q
E
I
F
S
N
E
M
A
K
V
DDSFFHRLERHPIFGN
I
V
D
E
V
A
Y
H
E
K
Y
PT
I
Y
H
L
R
K
K
L
V
D
STDKAD
L
R
L
I
Y
L
A
L
A
H
M
I
K
F
RGHFLIEGDLNPDNSD
V
D
K
L
F
I
Q
L
V
Q
T
Y
N
Q
L
F
EE
N
P
I
N
ASGVD
A
K
A
I
L
S
ARLS
K
S
R
R
L
E
N
L
I
A
Q
L
PGEKKNG
L
F
G
N
L
I
A
L
S
L
G
L
T
P
N
FKSNFDLA
E
D
A
K
L
Q
LSKDT
Y
D
D
D
L
D
N
L
L
A
Q
IGDQY
A
D
L
F
L
A
A
K
N
L
S
D
A
I
L
L
S
D
I
L
RKA
P
L
S
A
S
M
I
K
R
Y
D
E
H
H
Q
D
L
T
L
L
K
A
L
V
R
Q
QLPEKYKEIFFDQSKNG
Y
A
G
Y
I
DGGAS
Q
E
E
F
Y
K
F
I
K
P
I
L
E
K
M
DGTE
E
L
L
V
K
L
N
R
EDLLRKQRTFDN
G
S
I
P
H
Q
I
H
L
G
E
L
H
A
I
L
R
R
Q
EDFY
P
F
L
K
D
N
R
E
K
I
E
K
I
L
T
FRPN
E
K
V
L
PKHS
L
L
Y
E
Y
F
T
V
Y
N
E
L
TKVLS
G
E
Q
K
K
A
I
V
D
--
L
--
L
F
K
T
N
R
K
V
T
V
K
Q
L
K
E
D
F
N
A
----------------------------------------
S
L
------------------
G
T
Y
H
D
L
L
K
-----------
I
I
K
--
D
K
D
F
L
D
--
N
E
E
N
E
D
I
L
---
E
D
I
V
L
T
L
T
--
L
F
E
D
R
E
M
I
E
E
---
R
L
K
T
Y
--
A
H
L
---
F
D
D
K
V
M
K
Q
L
-
K
R
---
R
R
Y
T
-
G
W
G
R
L
S
R
K
L
I
N
G
I
R
-
D
K
T
I
---------------
L
D
F
L
K
R
N
F
M
----
Q
L
-
I
H
D
D
S
L
T
F
K
E
D
I
Q
K
A
Q
V
S
----
D
---------
S
L
H
E
--
H
I
A
-----------
N
L
A
G
S
P
A
I
K
K
G
------------
I
L
Q
T
V
K
V
V
D
E
L
V
K
------
V
M
G
R
H
K
P
E
---------------------
N
I
------
V
---------
I
E
-------
M
A
K
N
---------
S
R
E
R
M
K
R
I
----
E
E
G
I
K
E
---
L
H
P
V
E
----------
N
-------------
T
Q
L
Q
N
E
---------
K
L
Y
L
----
Y
Y
L
Q
N
G
R
D
M
Y
V
D
Q
E
L
D
I
NRLSDY
D
V
D
H
IVPQSFLKDDSIDN
K
V
L
T
RKNRGKSDNVPSEEVVKKM
K
N
Y
W
R
Q
L
L
N
A
KLIT
Q
R
K
F
D
N
L
T
KLS
E
L
D
K
A
G
F
I
K
R
Q
L
VETR
Q
I
T
K
H
V
A
Q
I
L
D
S
R
M
N
TKYDENDKLIRE
V
K
V
I
T
L
K
S
K
L
V
S
D
F
R
K
D
F
QFYKVREINN
Y
H
H
A
H
D
A
Y
L
N
A
V
V
G
T
A
L
I
K
K
YPKLESEFVYGDYKVYDVRKMIAKSEQYFFYSNIMNFFKT
E
I
T
L
ANG
E
I
R
K
R
P
L
I
E
T
N
GETGEIVWDKG
R
D
F
A
T
V
R
K
V
L
S
MP
Q
V
N
I
V
K
K
T
E
V
Q
TPTVA
Y
S
V
L
V
VS
V
K
E
L
L
G
I
T
I
M
E
R
S
S
F
E
K
N
P
I
D
F
L
E
A
K
GKDLI
I
K
L
P
KY
S
L
F
E
L
E
NG
R
K
R
M
L
ASAGELQKG
N
E
L
A
L
P
S
K
Y
V
N
F
L
Y
L
A
S
H
YVEQH
K
H
Y
L
D
E
I
I
E
Q
I
S
E
F
S
K
R
VILA
D
A
N
L
D
K
V
L
S
A
Y
N
K
H
R
DKP
I
R
E
Q
A
E
N
I
I
H
L
F
T
L
T
NLG
A
P
A
A
F
K
Y
FD
T
T
I
D
R
KRYTST
K
E
V
L
D
A
T
L
I
H
Q
S
ITGL
Y
E
T
R
I
D
LS
47
Fugue
46.30
12%
61
- C3 -
-
3H2U
-
RAVR1_HUMAN
B:
[39-317]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LD
P
E
E
I
R
K
R
L
E
H
T
E
--
R
--
Q
F
R
N
R
R
K
I
L
I
R
G
L
P
G
D
V
T
N
Q
--------
E
V
H
D
L
L
S
D
Y
-------
E
-----------
L
K
Y
C
F
------------------
V
D
K
Y
K
G
T
A
-----------
F
V
T
L
L
N
G
E
Q
A
E
A
A
I
N
A
F
H
Q
S
R
LRE
R
E
L
S
V
Q
L
Q
--
P
T
D
A
L
L
C
V
A
N
LPP
S
L
T
Q
Q
Q
F
E
E
L
---
V
R
P
F
G
S
L
E
R
-
C
F
---
L
V
Y
S
-
E
R
T
G
-------
Q
S
K
-
G
Y
G
F
---------------
A
E
Y
M
K
K
D
S
A
----
A
R
-
A
K
S
D
L
L
G
K
P
L
G
P
R
T
L
Y
V
H
----
W
---------
T
D
A
G
QL
T
P
A
-----------
L
L
H
S
R
C
L
C
V
D
R
------------
L
P
P
G
F
N
D
V
D
A
L
C
R
------
A
L
S
A
V
H
S
P
T
----------------
F
---
C
Q
------
L
---------
A
C
-------
G
Q
D
G
---------
Q
L
K
G
F
A
V
L
E
Y
ET
A
E
M
A
E
E
---
A
Q
Q
Q
A
D
--------
G
L
-------------
S
L
G
G
S
H
L
R
V
S
F
C
APG
P
P
G
R
----
S
M
L
A
A
L
I
A
A
Q
A
T
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
Fugue
45.51
18%
59
- C2 -
-
1CPO
14
?
?:
[121-299]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NSND
F
I
D
N
R
N
F
D
A
--
E
--
T
F
Q
T
S
L
D
V
V
A
G
K
T
H
F
D
-----------------------------------------------------------------------------------
Y
A
--
D
M
N
E
I
R
L
Q
R
E
S
L
S
N
E
L
-------
D
F
P
G
--
W
F
T
E
S
K
P
I
Q
N
---
V
E
S
G
F
I
F
A
L
V
---
S
D
F
-------------
N
L
P
-
D
N
D
E
N
P
L
V
R
I
-
D
W
W
-
K
Y
W
F
---------------
T
N
-----------
E
S
-
F
P
Y
H
L
-
G
W
H
P
P
S
P
A
R
E
I
E
----
F
---------
V
T
S
A
--
S
S
A
-----------
V
L
A
A
--------------------------
S
V
T
S
T
P
------
S
S
L
P
S
G
A
------------------------------------------------------------------
I
G
P
G
----
A
E
A
V
P
L
---
S
F
A
S
T
M
--------
T
P
-------------
F
L
L
A
T
N
---------
A
P
Y
Y
----
A
Q
D
P
T
---
L
G
P
N
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
43.94
28%
3
- C4 -
-
2YJE
2
ACTS_RABIT
A:
[194-278]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
-
T
E
R
-
G
Y
S
F
---------------
V
T
T
A
E
R
E
I
V
R
D
I
K
E
K
-
L
C
Y
V
A
L
D
F
E
N
E
M
A
T
A
A
S
S
----
S
---------
S
L
E
K
--
S
Y
E
-----------
L
P
D
G
Q
V
I
T
I
G
N
------------
E
R
F
R
C
P
E
T
L
F
Q
P
S
------
F
I
G
M
E
S
A
G
I
----------------
H
---
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
43.74
28%
8
- C4 -
-
2VYP
1
ACTS_RABIT
A:
[194-278]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
-
T
E
R
-
G
Y
S
F
---------------
V
T
T
A
E
R
E
I
V
R
D
I
K
E
K
-
L
C
Y
V
A
L
D
F
E
N
E
M
A
T
A
A
S
S
----
S
---------
S
L
E
K
--
S
Y
E
-----------
L
P
D
G
Q
V
I
T
I
G
N
------------
E
R
F
R
C
P
E
T
L
F
Q
P
S
------
F
I
G
M
E
S
A
G
I
----------------
H
---
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
43.28
28%
1
- C4 -
-
3DAW
1
ACTS_RABIT
A:
[194-278]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
-
T
E
R
-
G
Y
S
F
---------------
V
T
T
A
E
R
E
I
V
R
D
I
K
E
K
-
L
C
Y
V
A
L
D
F
E
N
E
M
A
T
A
A
S
S
----
S
---------
S
L
E
K
--
S
Y
E
-----------
L
P
D
G
Q
V
I
T
I
G
N
------------
E
R
F
R
C
P
E
T
L
F
Q
P
S
------
F
I
G
M
E
S
A
G
I
----------------
H
---
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
43.11
12%
67
- C1 -
-
1JTD
-
?
B:
[1-273]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
A
T
S
V
V
A
W
G
G
--
N
N
D
W
G
E
A
T
V
P
A
E
A
Q
S
G
V
D
A
I
--------
A
G
G
Y
F
H
G
L
A
-------
L
K
GGKVL-----
G
W
G
A
N
LNGQLTMPAATQSGVD
A
I
A
A
G
N
Y
H
S
L
-----------
A
L
K
--
D
-
G
E
V
I
A
W
G
G
N
E
D
G
Q
T
---
T
V
P
A
E
A
R
S
--
G
V
D
A
I
A
A
G
A
W
---
A
S
Y
A
L
K
D
G
K
V
---
I
A
W
G
D
-
D
S
D
-
G
Q
---
T
T
V
P
-
A
E
A
Q
S
G
V
T
A
L
-
D
G
G
-
V
Y
T
A
---------------
L
A
V
K
N
G
G
V
I
----
A
W
G
D
N
Y
F
G
Q
T
T
V
P
A
E
A
Q
S
G
V
D
----
D
---------
V
A
G
G
--
I
F
H
-----------
S
L
A
L
K
D
G
K
V
I
A
------------
W
G
D
N
R
Y
K
Q
T
T
V
P
T
------
E
A
L
S
G
V
S
A
I
----------------
A
S
G
E
W
Y
------
S
---------
L
A
-------
L
K
N
G
---------
K
V
I
A
W
G
S
S
----
R
T
A
P
S
S
---
V
Q
S
--
G
--------
V
S
-------------
S
I
E
A
G
P
---------
N
A
A
Y
----
A
L
K
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
42.83
28%
4
- C4 -
-
2V51
3
ACTS_RABIT
B:
[194-278]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
-
T
E
R
-
G
Y
S
F
---------------
V
T
T
A
E
R
E
I
V
R
D
I
K
E
K
-
L
C
Y
V
A
L
D
F
E
N
E
M
A
T
A
A
S
S
----
S
---------
S
L
E
K
--
S
Y
E
-----------
L
P
D
G
Q
V
I
T
I
G
N
------------
E
R
F
R
C
P
E
T
L
F
Q
P
S
------
F
I
G
M
E
S
A
G
I
----------------
H
---
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
42.68
28%
18
- C4 -
-
1P8Z
1
ACTS_RABIT
A:
[194-278]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
-
T
E
R
-
G
Y
S
F
---------------
V
T
T
A
E
R
E
I
V
R
D
I
K
E
K
-
L
C
Y
V
A
L
D
F
E
N
E
M
A
T
A
A
S
S
----
S
---------
S
L
E
K
--
S
Y
E
-----------
L
P
D
G
Q
V
I
T
I
G
N
------------
E
R
F
R
C
P
E
T
L
F
Q
P
S
------
F
I
G
M
E
S
A
G
I
----------------
H
---
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
42.68
28%
50
- C4 -
-
3W3D
1
ACTH_CHICK
A:
[193-275]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
-
T
E
R
-
G
Y
S
F
---------------
V
T
T
A
E
R
E
I
V
R
D
I
K
E
K
-
L
C
Y
V
A
L
D
F
E
N
E
M
A
T
A
A
S
S
----
S
---------
S
L
E
K
--
S
Y
E
-----------
L
P
D
G
Q
V
I
T
I
G
N
------------
E
R
F
R
C
P
E
T
L
F
Q
P
S
------
F
I
G
M
E
S
A
G
I
----------------
H
---
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
42.57
28%
2
- C4 -
-
3FFK
1
ACTS_RABIT
B:
[194-278]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
-
T
E
R
-
G
Y
S
F
---------------
V
T
T
A
E
R
E
I
V
R
D
I
K
E
K
-
L
C
Y
V
A
L
D
F
E
N
E
M
A
T
A
A
S
S
----
S
---------
S
L
E
K
--
S
Y
E
-----------
L
P
D
G
Q
V
I
T
I
G
N
------------
E
R
F
R
C
P
E
T
L
F
Q
P
S
------
F
I
G
M
E
S
A
G
I
----------------
H
---
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
42.36
28%
7
- C4 -
-
1IJJ
2
ACTS_RABIT
A:
[194-278]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
-
T
E
R
-
G
Y
S
F
---------------
V
T
T
A
E
R
E
I
V
R
D
I
K
E
K
-
L
C
Y
V
A
L
D
F
E
N
E
M
A
T
A
A
S
S
----
S
---------
S
L
E
K
--
S
Y
E
-----------
L
P
D
G
Q
V
I
T
I
G
N
------------
E
R
F
R
C
P
E
T
L
F
Q
P
S
------
F
I
G
M
E
S
A
G
I
----------------
H
---
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
42.27
28%
24
- C4 -
-
1SQK
2
ACTS_RABIT
A:
[194-278]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
-
T
E
R
-
G
Y
S
F
---------------
V
T
T
A
E
R
E
I
V
R
D
I
K
E
K
-
L
C
Y
V
A
L
D
F
E
N
E
M
A
T
A
A
S
S
----
S
---------
S
L
E
K
--
S
Y
E
-----------
L
P
D
G
Q
V
I
T
I
G
N
------------
E
R
F
R
C
P
E
T
L
F
Q
P
S
------
F
I
G
M
E
S
A
G
I
----------------
H
---
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
42.15
11%
-193
- C4 -
-
4B5T
3
HPCH_ECOLC
B:
[5-41]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
K
A
A
---
L
K
A
G
R
P
Q
I
G
-
L
W
---
L
G
L
S
-
S
S
Y
S
A
E
L
L
---
A
G
A
-
G
F
D
W
---------------
L
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
42.10
25%
20
- C4 -
-
4GMO
-
?
A:
[600-675]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
L
N
Q
L
F
----
D
---------
I
Y
G
D
--
E
E
L
ACDKEVFWKDG
F
L
K
H
L
E
E
F
L
P
K
------------
M
R
T
L
T
K
G
I
-
D
K
R
T
------
Q
-
P
E
L
R
T
R
A
----------------
D
---
E
A
L
L
N
L
G
R
F
---------
V
Q
-------
Y
K
K
K
---------
H
A
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
41.49
28%
3
- C4 -
-
3B5U
-
ACTS_RABIT
A:
[192-276]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
-
T
E
R
-
G
Y
S
F
---------------
V
T
T
A
E
R
E
I
V
R
D
I
K
E
K
-
L
C
Y
V
A
L
D
F
E
N
E
M
A
T
A
A
S
S
----
S
---------
S
L
E
K
--
S
Y
E
-----------
L
P
D
G
Q
V
I
T
I
G
N
------------
E
R
F
R
C
P
E
T
L
F
Q
P
S
------
F
I
G
M
E
S
A
G
I
----------------
H
---
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
41.47
28%
-17
- C4 -
-
5NOG
1
?
A:
[188-272]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
-
T
E
R
-
G
Y
S
F
---------------
V
T
T
A
E
R
E
I
V
R
D
I
K
E
K
-
L
C
Y
V
A
L
D
F
E
N
E
M
A
T
A
A
S
S
----
S
---------
S
L
E
K
--
S
Y
E
-----------
L
P
D
G
Q
V
I
T
I
G
N
------------
E
R
F
R
C
P
E
T
L
F
Q
P
S
------
F
I
G
M
E
S
A
G
I
----------------
H
---
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
41.33
28%
6
- C4 -
-
3CJC
1
ACTS_RABIT
A:
[194-278]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
-
T
E
R
-
G
Y
S
F
---------------
V
T
T
A
E
R
E
I
V
R
D
I
K
E
K
-
L
C
Y
V
A
L
D
F
E
N
E
M
A
T
A
A
S
S
----
S
---------
S
L
E
K
--
S
Y
E
-----------
L
P
D
G
Q
V
I
T
I
G
N
------------
E
R
F
R
C
P
E
T
L
F
Q
P
S
------
F
I
G
M
E
S
A
G
I
----------------
H
---
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------