Atome 2 Filter

@TOME V2.3
(Mar 2018)

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Sequence color : MutatedHelixStrandConserved

Query sequence : JAK2_HUMAN: (2017-06-02 )
CHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCY

Atome Classification :

	(20 SA)										--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20........30........40-.---...--...--.50........-60----------------..-.....--.----.70........80.---------------------------------
		(Atome)	(Ident)	(Tito)	(Num)	(QMean)		(Ligand)	(Uniprot)		--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFA-V---ERE--NVI--EYKHCLITKNE-N-----------------EE-YNLSG--T----KKNFSSLKDLLNCY---------------------------------
1	PsiBlast_PDB	94.29	100%	-162	- C1 -	-	4Z32	-	JAK2_HUMAN	A:[371-452]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFA-V---ERE--NVI--EYKHCLITKNE-N-----------------EE-YNLSG--T----KKNFSSLKDLLNCY---------------------------------
13	HHSearch	62.90	29%	-139	- C1 -	-	4FL3	-	KSYK_HUMAN	A:[16-181]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVA-H---GR--------KAHHYTIEREL-N-----------------GT-YAIAG-------GRTHASPADLCHYH---------------------------------
15	HHSearch	62.01	24%	-130	- C1 -	-	3PQZ		GRB7_HUMAN	A:[17-97]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FHGRISREESQRLIGQQGLVDGLFLVRESQR-PQGFVLSLC-H---LQ----K----VKHYLILPSEEE-----------------GR-LYFSMDDG----QTRFTDLLQLVEFH---------------------------------
5	HHSearch	61.45	29%	-166	- C1 -	-	2OZO	-	ZAP70_HUMAN	A:[11-154]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLV-H---DV----R----FHHFPIERQL-N-----------------GT-YAIAG-------GKAHCGPAELCEFY---------------------------------
22	HHSearch	60.95	21%	-154	- C1 -	-	1OPK	-	ABL1_MOUSE	A:[108-182]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHGPVSRNAAEYLLS--SGINGSFLVRESESSPGQRSISLR-Y---EG----R----VYHYRINTAS-D-----------------GK-LYVSS-------ESRFNTLAELVHHH---------------------------------
8	HHSearch	60.03	29%	-148	- C1 -	-	1RJA	-	PTK6_HUMAN	A:[5-81]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVR-D---TQ----A----VRHYKIWRRA-G-----------------GR-LHLNE-------AVSFLSLPELVNYH---------------------------------
14	HHSearch	59.20	21%	-172	- C1 -	-	4EIH	-		A:[15-89]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHGPVSRSAAEYLLS--SLINGSFLVRESESSPGQLSISLR-Y---EG----R----VYHYRINTTA-D-----------------GK-VYVTA-------ESRFSTLAELVHHH---------------------------------
24	HHSearch	58.83	21%	-156	* C1 *	-	3WA4		GRB2_HUMAN	A:[7-81]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FFGKIPRAKAEEMLSK-QRHDGAFLIRESESAPGDFSLSVK-F---GN----D----VQHFKVLRDG-A-----------------GK-YFLW--------VVKFNSLNELVDYH---------------------------------
18	HHSearch	58.60	24%	-58	- C1 -	-	2H8H	-	SRC_HUMAN	A:[151-232]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVS-D---FDNAKGL---NVKHYKIRKLD-S-----------------GG-FYITS-------RTQFNSLQQLVAYY---------------------------------
21	HHSearch	57.58	19%	-151	- C1 -	-	1I3Z	-	SH21B_MOUSE	A:[6-86]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHGCLTKRECEALLLK-GGVDGNFLIRDSESVPGALCLCVS-F---KK----L----VYSYRIFREK-H-----------------GY-YRIET--DAHTPRTIFPNLQELVSKY---------------------------------
12	HHSearch	57.58	25%	-33	- C1 -	-	4U1P		FYN_HUMAN	A:[24-105]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIR-D---WDDMKGD---HVKHYKIRKLD-N-----------------GG-YYITT-------RAQFETLQQLVQHY---------------------------------
11	HHSearch	56.04	23%	-42	- C1 -	-	4D8K			A:[77-158]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVR-D---FDQNQGE---VVKHYKIRNLD-N-----------------GG-FYISP-------RITFPGLHELVRHY---------------------------------
2	PsiBlast_PDB	55.52	34%	-74	- C1 -	-	5L04	-	?	A:[411-495]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTCF---EK------QKQFKNFQIEVQK-G------------------R-YSLHG--S----DRSFPSLGDLMS-----------------------------------
3	PsiBlast_PDB	53.26	34%	-157	- C1 -	-	5IXI	-	JAK1_HUMAN	A:[422-506]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CHGPICTEYAINKLRQE------YVLRWSCTDFDNILMT--------------------NFQI-EVQ-K-----------------GR-YSLHG--S----DRSFPSLGDLMS-----------------------------------
23	HHSearch	53.22	26%	-56	- C1 -	-	1BLJ	-		A:[15-95]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FFRTISRKDAERQLLAPMNKAGSFLIRESESNKGAFSLSVK-DITTQG---EV----VKHYKIRSLD-N-----------------GG-YYISP-------RITFPTLQALVQHY---------------------------------
20	HHSearch	52.20	23%	-36	- C1 -	-	1LKK		LCK_HUMAN	A:[7-88]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVR-D---FDQNQGE---VVKHYKIRNLD-N-----------------GG-FYISP-------RITFPGLHELVRHY---------------------------------
10	HHSearch	52.01	26%	-93	- C1 -	-	1JU5		CRK_HUMAN	A:[3-93]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YWGRLSRQEAVALLQ--GQRHGVFLVRDSSTSPGDYVLSVS-E---NS----R----VSHYIINSSG-PRPPVPPSPAQPPPGVSPSR-LRI-G-------DQEFDSLPALLEFY---------------------------------
17	HHSearch	51.61	24%	-101	- C1 -	-	2DVJ	-	CRK_HUMAN	A:[14-104]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YWGRLSRQEAVALLQ--GQRHGVFLVRDSSTSPGDYVLSVS-E---NS----R----VSHYIINSSG-PRPPVPPSPAQPPPGVSPSR-LRIG--------DQEFDSLPALLEFY---------------------------------
26	Fugue	51.15	25%	-6	- C1 -	-	4PO6		TYK2_HUMAN	A:[6-546]	GGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDAGPPTHEVLVTGTGGIQWWPVEPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVA-Q---RSQ--APD--GMQSLRLRKFP-I-----------------EQAFVLEG--W----GRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRG
16	HHSearch	49.83	24%	-56	- C1 -	-	2EYZ	-	CRK_HUMAN	A:[14-104]	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YWGRLSRQEAVALLQ--GQRHGVFLVRDSSTSPGDYVLSVS-E---NS----R----VSHYIINSSG-PRPPVPPSPAQPPPGVSPSR-LRIG--------DQEFDSLPALLEFY---------------------------------