@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0143: (2017-12-16 )
MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLSDMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPPTRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVLGSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLLMLL
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.-.---------......20--....-------..------..-------------30...-.....-------40.......-------------------.50.----.......60..--------......70..------......--------80.......-----..90.-----.------------...-------------....--100.......110.......120.--.-----.....130..----..--....140.....---..------150.---....------..160..---------------...-..-170..-.---------------....180----------.......190...-..---.-.200..-.-----..----------..210-.......220---------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
K
I
ISH
R
Y
F
I
I
-
V
---------
F
L
L
V
IADQ--
K
F
S
V
-------
L
V
------
L
R
-------------
S
D
L
V
A
-
G
L
S
D
F
-------
A
Y
Y
L
S
D
M
M
L
-------------------
N
F
L
V
----
V
L
F
A
L
I
A
M
I
WS--------GK
W
Q
KINSRK------FK
G
S
Y
L
--------
F
-
Y
S
F
L
A
L
L
-----
A
F
V
-
A
-----
W
------------
N
F
V
-------------
T
F
F
L
--FPPTRNEISYQHAAPTF
T
G
A
T
A
F
L
--
M
-----
Y
F
F
Y
P
VI-A
G
----
P
I
--
F
E
D
M
I
Y
R
G
L
V
M
T
---
A
L
------
E
KGK---KW
G
L
------
D
V
L
G
S
A
V
---------------
L
F
G
-
V
S
-
H
ISNH-G---------------W
V
L
T
D
F
V
----------
F
Y
MG
G
G
L
I
F
A
V
L
F
-
R
M
---
T
-
K
SIYW
P
-
I
-----
G
L
----------
H
I
V
Y
N
-
G
I
G
Q
L
L
M
LL----------------------------------------------------------------------------------------------
18
Fugue
65.49
17%
-54
- C3 -
-
5B3F
-
?
A:
[26-339]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N
F
R
E
V
I
R
H
S
P
--
L
-
V
---------
Y
L
I
G
V
A
G
D
--
S
G
S
----------------
G
K
-------------
S
T
F
T
R
-
A
I
S
D
I
FGEEL
V
S
S
I
T
V
D
D
Y
H
L
YD
R
K
T
R
S
E
M
GITPLLHTAN
N
L
K
L
----
L
E
E
N
L
M
D
L
K
A
G
--------
R
T
I
Q
K
P
V
Y
L
H
------
D
H
G
T
F
G
--------
E
-
P
E
L
F
S
P
T
-----
K
F
I
-
I
-----
I
E
GLHPYAT
K
S
L
R
A
L
Y
-------------
D
Y
T
I
--
F
V
D
P
E
R
D
V
K
Y
D
W
K
I
R
R
D
N
E
V
L
R
E
I
--
L
Q
R
E
P
D
Y
F
Q
Y
V
F
P
-
Q
R
----
E
V
--
A
D
A
V
I
Q
I
S
Y
S
S
Y
---
G
K
------
E
E
G
E
---
K
R
N
V
------
Y
R
V
M
L
S
M
P
AQEYCF
E
D
I
E
L
N
I
D
L
C
D
-
L
F
-
K
K
S
S
H
-
D
---------------
F
S
L
S
C
I
S
H
T
P
DS
R
N
M
R
A
L
V
V
D
G
E
L
M
P
D
T
I
H
-
K
I
---
E
-
R
Q
I
E
F
Q
-
T
-----
G
I
SPINIFRGQE
H
I
T
G
T
-
D
L
V
R
L
I
L
S
W
Q
I
I
N
G
R
I
A
L
S
N-----------------------------------------------------------------------------------
20
Fugue
64.34
19%
-185
* C4 *
-
5JKI
5
YODM_BACSU
A:
[20-220]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
K
P
V
S
L
F
L
F
F
L
-
I
---------
L
A
A
A
I
H
T
N
--
A
V
Q
S
-------
A
D
------
E
A
-------------
I
S
K
A
A
-
V
L
I
R
Q
-------
P
W
L
N
E
V
M
T
G
-------------------
I
T
H
L
G
A
S
S
F
L
L
P
L
I
V
I
I
G
A
--------
G
M
F
F
Y
R
K
T
W
D
------
G
L
L
M
L
L
--------
V
-
F
G
T
D
R
L
L
-----
N
K
V
-
L
-----
K
------------
E
W
I
-------------
E
R
V
R
PD
F
A
P
L
V
H
E
S
S
F
-----
S
F
P
S
G
H
S
M
N
--
A
-----
A
C
V
Y
P
V
I
-
A
Y
----
F
L
--
V
K
H
L
P
F
L
S
---------------
K
H
K
K
---
M
V
Y
I
------
I
A
G
V
I
A
V
---------------
L
V
G
-
I
S
-
R
V
Y
L
G
-
V
---------------
H
F
V
T
D
V
L
----------
G
G
F
S
L
G
L
L
L
F
F
L
V
-
K
G
---
F
-
D
E
K
I
K
R
-
F
-----
R
------------------------------------------------------------------------------------------------------------------------
21
Fugue
63.48
18%
-44
- C4 -
-
5FYP
2
?
A:
[2-298]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QESPAFID
P
A
S
W
N
TPFNG
I
A
Q
V
A
C
H
NCYEKQYANT
F
S
S
V
L
D
S
---
V
R
-
T
---------
L
E
L
D
F
W
D
Q
--
R
D
A
V
S
G
G
S
P
H
H
W
F
------
V
R
HNPGSGNDNNCTK
N
D
L
E
A
-
C
L
N
D
V
-------
K
N
W
S
D
K
H
P
G
-------------------
H
F
P
I
----
T
L
I
L
D
K
K
Q
G
W
S
K
ESSGRT
P
K
D
F
D
E
L
V
A
R
V
------
F
Q
G
K
L
F
--------
T
-
P
Q
D
L
A
T
H
I
GSGA
G
A
L
-
Q
-----
G
------------
N
L
K
GKSWPTANDLQG
K
V
L
L
V
--
L
N
H
S
E
N
Q
K
L
S
Q
Y
A
E
A
R
T
S
K
A
K
V
F
I
S
P
V
-----
T
N
G
Q
N
D
I
-
S
G
----
K
V
SG
M
S
S
Q
S
S
G
Y
V
A
M
N
---
N
M
G
-----
K
G
D
K
---
S
W
A
K
------
Q
A
F
A
Y
----------------------
S
-
H
I
G
R
V
W
G
---------------
D
D
E
V
S
F
A
----------
Q
H
I
N
Q
K
I
N
L
S
A
Y
Y
-
R
F
---
A
-
A
Q
--
S
A
-
G
-----
G
Y
----------
R
I
R
P
F
--------------------------------------------------------------------------------------------------------
13
Fugue
60.64
16%
-68
- C3 -
-
3C24
1
?
A:
[6-285]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
D
V
G
P
K
T
V
A
I
-
L
GAGGKMG
A
R
I
T
R
K
I
H
D
S
--
A
H
H
L
-------
A
A
I
E
IA
P
E
G
R
-------------
D
R
L
Q
G
M
G
I
P
L
T
-------
D
G
--
D
G
W
I
D
-------------------
E
A
D
V
----
V
V
L
A
L
P
D
N
I
I
E
--------
K
V
A
E
D
I
V
P
R
V
------
R
P
G
T
I
V
--------
L
I
L
D
A
A
A
P
Y
-----
A
G
V
M
P
ERAD
I
T
------------
Y
F
I
-------------
G
H
P
C
--
H
P
P
L
F
N
D
E
T
D
P
A
A
R
T
D
Y
H
G
G
I
A
----
K
-----
Q
A
I
V
C
A
L
M
Q
G
----
P
E
--
E
H
Y
A
I
G
A
D
I
C
E
T
M
W
S
P
V
------
T
R
T
H
---
R
V
T
T
------
E
Q
L
A
I
L
E
PG-------------
L
S
E
M
V
A
M
P
F
V
E
T
M
V
---------------
H
A
V
D
E
C
A
----------
D
R
Y
G
I
D
R
Q
A
A
L
D
F
M
I
G
---
H
-
L
N
V
E
I
A
M
W
F
GYSP
K
V
----------
A
A
L
R
L
M
E
F
A
K
D
I
V
V
K
EDWREALN
P
A
K
V
K
Q
A
A
E
L
I
A
G-------------------------------------------------------------------------
22
Fugue
57.74
16%
-52
- C2 -
-
2PO4
-
RPOLV_BPN4
A:
[11-1104]
G
I
D
A
V
Y
PSLVGTADSKAEGIKN
Y
F
K
L
S
F
TLPEEQKSRTVGSEA
P
L
K
D
V
A
Q
A
L
SS
R
A
R
Y
E
L
F
T
EKETANPAFN
G
E
V
I
K
R
Y
K
E
L
M
E
H
G
E
G
I
A
D
I
L
R
S
R
L
A
K
F
L
N
TKD
V
G
K
R
F
A
Q
GTEANRWVGGKLLNI
V
E
Q
D
GD
T
F
K
Y
N
E
Q
L
L
Q
T
A
V
L
A
G
L
Q
W
R
L
TATSNTAIKD
A
K
D
V
A
A
I
T
GIDQALLP
E
G
L
V
E
Q
F
D
T
G
MT
L
T
E
A
V
S
S
L
A
Q
K
I
E
S
Y
W
GLSRNPNAPLGYT
K
G
I
P
T
A
M
A
A
E
I
L
A
A
F
V
E
S
TD
V
V
E
N
I
V
D
MSEIDPDNK
K
T
I
G
L
Y
T
I
TELDSFD
P
I
N
S
F
PT
A
I
E
E
A
V
L
V
NPT
E
K
M
F
F
GDDIPPVANTQLRNPAVRNT
P
E
Q
K
A
A
L
K
A
E
Q
A
T
E
F
Y
V
H
T
P
M
V
Q
F
Y
E
T
L
G
K
D
R
I
L
E
L
M
G
AGTLNKELLN
D
N
H
A
K
S
L
E
G
K
N
R
S
V
E
D
S
Y
N
Q
L
F
S
V
I
E
Q
V
R
A
Q
SEDIST
V
P
I
H
Y
A
Y
N
M
T
RVG
R
M
Q
M
L
GKYNPQSA
K
L
V
R
E
A
I
LP
T
K
A
T
L
DLSNQNN
E
D
F
S
A
F
Q
L
G
L
A
Q
A
L
DIKVHTMT
R
E
V
M
S
D
E
L
T
K
L
L
E
G
NL
K
P
A
I
D
M
M
V
E
F
N
T
TGSLPEN
A
V
D
V
L
N
T
A
L
GDRKS
F
V
A
L
M
A
L
M
E
Y
S
R
Y
L
V
AEDKS
A
F
V
T
P
L
Y
V
E
ADGVT
N
G
P
I
N
A
M
M
L
MTGGLFT
P
D
W
I
R
N
I
A
K
G
GLFIGSPNKT
M
N
E
H
R
S
TADNND
L
Y
Q
A
S
T
N
A
L
M
E
S
L
G
K
L
R
S
N
Y
A
SN
M
P
I
Q
S
Q
I
D
S
L
L
S
L
M
D
L
FLPDINLGENGALELKRGIAKN
P
L
T
I
T
I
Y
GSG
A
R
G
I
A
G
K
L
V
S
S
V
T
D
A
I
Y
E
R
M
S
D
V
L
K
A
R
A
K
DPNIS
A
A
M
A
M
FGKQAAS
E
A
H
A
E
E
L
L
A
R
F
L
K
D
M
E
T
L
T
S
T
V
P
V
K
R
KG
V
L
E
L
Q
S
TGTGA
K
G
K
I
N
P
K
T
Y
T
I
K
G
E
---------
Q
L
K
A
L
Q
E
N
M
L
H
F
F
V
-------
E
P
------
L
R
-------------
N
G
I
T
Q
-
T
V
G
E
S
-------
L
V
Y
S
T
E
Q
L
Q
-------------------
K
A
T
Q
----
I
Q
S
V
V
L
E
D
M
F
K
--------
Q
R
V
Q
E
K
L
A
E
K
A
K
DPTW
K
K
G
D
F
L
T
Q
K
E
L
N
D
I
Q
-
A
S
L
N
N
L
A
-----
P
M
I
-
E
-----
T
------------
G
S
Q
-------------
T
F
Y
I
--
A
G
S
E
N
A
E
V
A
N
Q
V
L
A
T
N
L
D
D
R
M
R
V
P
--
M
-----
S
I
Y
A
P
A
Q
-
A
G
VA
G
I
P
F
--
M
T
I
G
T
G
D
G
M
M
M
Q
---
T
L
------
S
T
M
K
GAP
K
N
T
L
------
K
I
F
D
-
G
M
---------------
N
I
G
-
L
N
-
D
I
T
D
A
-
S
---------------
R
K
A
N
E
A
V
----------
Y
T
S
W
Q
G
N
P
I
K
N
V
Y
-
E
S
---
Y
-
A
K
F
M
K
N
-
V
-----
D
F
----------
S
K
L
S
P
-
E
A
L
E
A
I
G
K
S
A
L
EYDQRENAT
V
D
D
I
A
N
A
A
S
L
I
E
R
N
L
R
N
I
A
L
G
V
D
I
R
H
K
V
L
D
K
V
N
L
S
I
DQMAAVG
A
P
Y
Q
NNGKIDLSNMT
P
E
Q
Q
A
D
E
L
N
K
L
F
R
E
E
L
E
A
R
K
Q
K
V
A
K
15
Fugue
57.30
18%
-97
- C1 -
-
2MHL
-
?
A:
[1-192]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
H
E
--
A
G
E
F
F
M
R
-
A
---------
G
S
A
T
V
R
P
T
--
E
G
A
-------------------------------
G
G
T
L
G
-
S
L
G
G
F
---------------------------------------------------------------
S
V
T
N
N
T
Q
L
G
------
L
T
F
T
Y
M
--------
A
-
T
D
N
I
G
V
E
-----
L
L
A
-
A
-----
T
------------
P
F
R
-------------
H
K
I
G
--
T
R
A
T
G
D
I
A
T
V
H
H
L
P
P
-------
T
L
--
M
-----
A
Q
W
Y
F
G
D
-
A
S
----
S
K
--
F
R
P
Y
V
G
A
G
I
N
Y
T
---
T
F
F
D
N
GFN
D
H
G
K
---
E
A
G
L
SDLS
L
K
D
S
W
G
A
A
G
---------------
Q
V
G
-
V
D
-
Y
L
I
N
R
-
D
---------------
W
L
V
N
M
S
V
----------
W
Y
M
D
I
D
--
T
T
A
N
Y
-
K
L
G
G
A
Q
-
Q
H
D
S
V
R
-
L
-----
D
P
----------
W
V
F
M
F
-
S
A
G
Y
R
F
-------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
57.03
25%
-247
- C5 -
-
4LMK
-
GLIC_GLOVI
A:
[198-269]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
I
P
N
I
I
L
-------------------
P
M
L
F
----
I
L
F
I
S
W
T
A
F
W
S
--------
T
S
Y
E
---------------
A
N
V
--------
T
-
L
V
V
S
T
L
I
-----
A
H
I
-
A
-----
F
------------
N
I
L
-------------
V
E
T
N
--
L
P
K
T
--------
P
A
M
T
Y
T
G
A
I
I
F
M
--
I
-----
Y
L
F
Y
F
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
55.36
25%
-249
- C5 -
-
3TLT
1
GLIC_GLOVI
A:
[201-272]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
I
P
N
I
I
L
-------------------
P
M
L
F
----
I
L
F
I
S
W
T
A
F
W
S
--------
T
S
Y
E
---------------
A
N
V
--------
T
-
L
V
V
S
T
L
I
-----
A
F
I
-
A
-----
F
------------
N
I
L
-------------
V
E
T
N
--
L
P
K
T
--------
P
Y
M
T
Y
T
G
A
I
I
F
M
--
I
-----
Y
L
F
Y
F
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
51.61
24%
-
- C5 -
-
4YEU
-
ELIC_DICCH (first)
A:
[187-275]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
S
R
-------
I
T
------
V
R
-------------
I
D
A
V
----
R
N
Y
-------
F
S
Y
I
P
N
I
I
L
-------------------
P
M
L
F
----
I
L
F
I
S
W
T
A
F
W
S
--------
T
S
Y
E
---------------
A
N
V
--------
T
-
L
V
V
S
T
L
I
-----
A
H
I
-
A
-----
F
------------
N
I
L
-------------
V
E
T
N
--
L
P
K
T
--------
P
Y
M
T
Y
T
G
A
I
I
F
M
--
I
-----
Y
L
F
Y
F
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
45.37
19%
-175
- C5 -
-
4CAD
1
RCE1_METMP
I:
[127-237]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-----
P
V
L
F
L
L
L
-
L
A
----
A
T
--
F
E
E
L
G
W
R
G
Y
A
F
D
---
S
L
------
Q
S
R
Y
---
S
L
F
K
------
A
S
I
L
F
G
I
---------------
F
W
S
-
L
W
-
H
F
P
L
I
-
F
VNNSYQYEIFNQSIW
Y
G
L
N
F
F
L
----------
S
I
L
P
M
G
I
I
I
T
W
M
C
-
L
K
---
N
R
K
S
I
I
L
A
-
I
-----
I
F
----------
H
F
L
I
N
-
L
N
Q
E
L
L
-------------------------------------------------------------------------------------------------
4
HHSearch
44.80
19%
-160
- C5 -
-
4CAD
1
RCE1_METMP
F:
[127-237]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-----
P
V
L
F
L
L
L
-
L
A
----
A
T
--
F
E
E
L
G
W
R
G
Y
A
F
D
---
S
L
------
Q
S
R
Y
---
S
L
F
K
------
A
S
I
L
F
G
I
---------------
F
W
S
-
L
W
-
H
F
P
L
I
-
F
VNNSYQYEIFNQSIW
Y
G
L
N
F
F
L
----------
S
I
L
P
M
G
I
I
I
T
W
M
C
-
L
K
---
N
R
K
S
I
I
L
A
-
I
-----
I
F
----------
H
F
L
I
N
-
L
N
Q
E
L
L
-------------------------------------------------------------------------------------------------
14
Fugue
44.69
9%
-170
- C3 -
-
1T6S
-
?
A:
[1-162]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
E
Q
R
Q
Q
L
L
R
S
L
-
E
---------
A
L
I
F
S
S
E
E
--
P
V
N
L
-------
Q
T
------
L
S
-------------
Q
I
T
A
H
-
K
F
T
-----------------
P
-------------------
S
E
L
Q
----
E
A
V
D
E
L
N
R
D
Y
E
--------
A
T
G
R
T
F
R
I
H
A
------
I
A
G
G
Y
R
--------
F
-
L
T
E
P
E
F
A
-----
D
L
V
-
R
-----
Q
------------
L
L
A
-------------
P
V
I
Q
--
R
R
L
S
R
S
M
L
E
V
L
A
V
V
A
W
H
Q
P
V
T
K
G
E
--
I
-----
Q
Q
I
R
G
A
S
-
P
D
----
Y
S
--
I
D
R
L
L
A
R
G
L
I
E
V
---
R
G
------
R
A
D
S
---
P
------------
G
R
P
L
---------------
Q
Y
G
-
T
T
--------------------------
E
V
F
L
----------
D
L
F
H
L
------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
43.50
35%
-475
- C5 -
-
2MN4
-
?
A:
[22-38]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
----
K
I
--
L
E
E
L
L
R
R
G
L
L
T
P
---
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
27.52
22%
-143
* C3 *
-
1RKL
-
OST4_YEAST
A:
[1-36]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
S
D
E
Q
L
-------------------
N
S
L
A
----
I
T
F
G
I
V
M
M
T
L
I
--------
V
I
Y
H
A
V
D
S
T
M
------
S
P
K
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
18.98
45%
150
* C5 *
-
1PEI
2
?
?:
[1-22]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
E
K
S
I
D
L
I
----------
Q
K
W
E
E
-
K
S
R
E
------
F
I
G
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
18.22
11%
-74
- C5 -
-
5FN5
-
APH1A_HUMAN
C:
[72-98]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
F
G
A
A
-
V
S
----
V
L
--
L
Q
E
V
-
F
R
F
A
Y
Y
K
---
L
L
------
K
K
A
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
14.74
31%
-14
- C5 -
-
2HAC
-
CD3Z_HUMAN
A:
[9-24]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
I
Y
G
V
I
L
T
A
L
F
-
L
R
---
V
-
K
-------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
14.56
20%
98
- C5 -
-
1DC1
-
T2B1_GEOSE
B:
[109-132]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
--
I
D
E
L
I
F
R
Y
L
L
F
Q
---
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
14.22
21%
-114
* C6 *
-
2CB2
-
SOR_ACIAM
D:
[289-308]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
Y
I
R
I
-
L
N
----
P
M
--
M
E
G
T
F
W
R
E
Y
L
N
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
13.16
11%
-
- C5 -
-
5A63
-
APH1A_HUMAN
C:
[72-98]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
F
G
A
A
-
V
S
----
V
L
--
L
Q
E
V
-
F
R
F
A
Y
Y
K
---
L
L
------
K
K
A
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------