@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKS7: (2017-10-29 )
MKLQTIACAVAIATGGLFFSHTMNEARAATNTAAVSQSIQPTQEQALVARQLATLVDRQHYLNMRLDANTSNRILDMYLDSLDPDHSLFLDAEVQNYKKLYGSNFGASLKAGNLTGPFAIHQQYRERLKQFYEFMLAELKKPQNLKQPNTFIEVDREKAPYFKTSAEQQNHWRKMLVSQLINLTISREEEQAKQKALKENPSLADGQDLTGPEDLTPAQTLTKRYTRQLERISRVKSDDVLDKTLNAMLATYDPHSNYYPPIDAIELNRQTTLQLEGIGVSIRPERGNEDYTKIETIVEGGPASKSGQVKSGDRIVGVAQEGGKMIDVVGWSSSEIVGLIRGKRGTKVTLKLLGAGASMSQARNVTLVRDVIQEEDAGVRSRTVEVTRDGKKHLLGVIEIPSFYFDYRSRRAGQQYRSVSEDTANAFEALKAKKVEGIIIDLRNDPGGSLEEVARMLGQVIKSGPVVQIRDGNGNVSVFEDNDGGQQIYTGPLAVLVNLASASASEIYSAAIQDYERGIIIGSTTTGKGTAQVQLDTLAYGQATLTQRKFYRVTGGSTQNKGVVPDIKLVDIYNEEFGERKSKNALKWDTIPTAPFKREGSVQPYVAKLSQLSEQRVAVDPQFKYLNKRTAIAKVTSDQKQVVLDIDKRRAELLSLEKQTLDAENERRIATGQKPFPNWESYQASLDALAESRAKMKANQRPALPEEETFVNEAANVLMDYAKLQNR
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90.......--.100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220---.......---230...-.-....240.....-..250-.......260.......270.......280......-.--290........300.......310....---...320-.......330.------------.....--..340-........350......-.360.......370...--------.-.-.-----.--380-----------------------------.----..----.....------.390.......400.......410.....----..420.......430.......440.......450--........-460....-...---.--470.------------------------------------------------------...----------...480.......490.......500.......510.......520-.-......530..-.....540.---......550.......560........--------570...-.-..-.580.......590..----------.....600--------..---.......610.......620-...--.....630.......640...----....650...--....660.......670...-....680.......690.......700.......710.......720.....-
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MK
L
Q
T
I
A
C
A
V
A
IATG
G
L
F
FSHTMN
E
A
RAAT
N
T
A
A
V
SQSIQ
P
T
Q
E
Q
A
L
V
A
R
Q
L
A
T
L
V
D
R
Q
H
Y
L
N
M
R
LDANTSN
R
I
L
D
M
Y
L
DSLDPDH
S
L
F
L
D
A
E
V
Q
N
Y
K
--
K
L
YGSNFGASLKAGNLTG
P
F
A
I
H
Q
Q
Y
R
E
R
L
K
Q
F
Y
E
F
M
L
A
E
LKKPQNLKQPN
T
F
I
E
V
DREKAPYFKT
S
A
E
Q
Q
N
H
W
R
K
M
L
V
S
Q
L
I
N
L
TIS
R
E
E
E
Q
A
K
Q
K
A
L
KENPSLADGQDLTGPEDL
T
P
A
Q
T
L
T
---
K
R
Y
T
R
Q
L
---
E
R
-
I
S
R-V-KS
D
D
V
L
D
K
T
L
N
A
-
M
L
ATY-DPHSNYYPPI
D
A
I
E
LNR
Q
T
T
L
Q
L
E
G
I
G
V
S
I
RPERGN-E--
D
-
Y
T
K
I
E
T
I
VEGGPASKSGQVKSG
D
R
I
V
---
G
V
AQEG-
G
K
M
I
D
V
VGW-S------------S
S
E
I
V
--
G
L
I
R--GKRG
T
K
V
T
L
K
L
LGAGAS-MSQAR
N
V
T
L
V
R
D
V
I
Q
EE--------D-A-G-----V--R-------------------------------
S
----
R
T
----
V
E
VTR------DGK
K
H
L
L
G
V
IEI
P
S
F
Y
F
D
Y
R
S
RRA
G
Q
Q
Y
R----SVSED
T
A
N
A
F
E
A
L
K
AKKV
E
G
I
I
I
D
LRNDPGG
S
L
E
---
E
V
A
R
M
L
G
Q
-
V
I-KSG
P
-
V
V
Q
---
I
--RDGN------------------------------------------------------G
N
V
----------
S
V
F
EDNDGG
Q
Q
I
YT
G
P
L
A
V
L
V
N
L
ASA
S
A
S
E
I
Y
S
A
A
I
Q
DYER
G
I
I
I
G-S-TTTGK
G
T
A
Q
V
Q
-
L
D
T
L
AYG
Q
A
---TL
T
Q
R
K
F
Y
R
VTGGSTQNK-GVVPD
I
K
L
--------
V
D
I
Y
N
E
-
E
-FG-ERKSKNALKWDTIPTA----------PFKREG----------SV---
Q
P
Y
V
A
K
L
S
Q
L
S
E
Q
RVAVDP--
Q
F
K
--
Y
LNKR
T
A
I
A
KVTSDQ
K
Q
V
V
L
D
----
I
D
K
R
R
A
E
L
L
S
--
L
E
K
Q
TLDAENERRIATGQKP-FP
N
W
E
S
Y
Q
A
S
L
D
A
L
A
E
S
R
A
K
MKANQRPALP
E
E
E
T
F
V
N
E
A
A
N
V
L
M
D
Y
A
K
LQNR-
54
Fugue
70.78
28%
68
- C1 -
-
4C2E
-
CTPB_BACSU
A:
[44-478]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
S
E
R
D
K
A
M
D
K
I
E
---
K
A
Y
E
L
I
S
---
N
E
Y
V
E
K
-
V
-
D
R
E
K
L
L
E
G
A
I
Q
G
-
M
L
S
T
L
N
D
P
Y
S
V
Y
M
D
K
Q
T
A
K
Q
F
S
D
S
L
D
S
S
F
E
G
I
G
A
E
V
G
M
E
D
G
-------
K
I
I
I
V
S
P
F
K
K
S
P
A
E
K
A
G
-
L
K
P
N
D
E
I
I
---
S
I
N
G
E
S
------
M
A
G
K
-
D
------------
L
N
H
A
V
--
L
K
I
R
--
G
K
K
G
S
S
V
S
M
K
I
Q
R
P
G
T
K
---
K
Q
L
S
F
R
I
K
R
A
E
I
P
L
E
--------
T
-
V
-
F
-----
A
--
S
-------------------------------
E
----
K
K
----
V
Q
------------
G
H
S
V
G
Y
I
A
I
S
T
F
S
------------
E
----
H
T
T
E
D
F
A
K
A
L
R
E
L
E
K
K
E
I
E
G
L
V
I
D
V
R
G
N
P
G
G
Y
I
Q
---
S
V
E
E
I
L
K
H
-
F
V
T
K
D
Q
P
-
Y
I
Q
---
I
--
A
E
R
N
------------------------------------------------------
G
D
K
----------
K
R
Y
F
S
T
L
T
H
K
K
A
Y
--
P
V
N
V
I
T
D
K
G
S
A
A
A
S
E
I
L
A
G
A
L
K
E
A
G
H
Y
D
V
V
G
-
D
-
T
S
F
G
K
G
T
V
Q
Q
A
-
V
P
M
G
D
G
S
N
I
---
K
L
T
L
Y
K
W
L
T
P
N
G
N
W
I
H
K
K
-
G
I
E
P
T
I
A
I
--------
K
Q
P
D
Y
F
-
S
-
A
G
-
P
L
Q
L
K
E
P
L
K
V
D
--------------------------------
M
---
N
N
E
D
V
K
H
A
Q
V
L
L
K
G
L
S
F
D
P
--
G
R
E
DG
Y
F
S
-
K
D
M
K
K
A
V
M
A
F
Q
D
Q
N
K
L
N
KTGI
I
D
T
R
T
A
E
T
L
N
Q
Q
I
E
K
K
K
S
D
E
K
N
D
L
Q
L
Q
T
A
L
K
S
-
L
F
---------------------------------------------------
5
PsiBlast_PDB
69.91
27%
63
- C1 -
-
4C2C
-
CTPB_BACSU
A:
[23-436]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
-
V
E
K
-
V
-
D
R
E
K
L
L
E
G
A
I
Q
G
-
M
L
S
T
L
N
D
P
Y
S
V
Y
M
D
K
Q
T
A
K
Q
F
S
D
S
L
D
S
S
F
E
G
I
G
A
E
V
G
M
E
D
G
K
-------
I
I
I
V
S
P
F
K
K
S
P
A
E
K
A
G
-
L
K
P
N
D
E
I
I
---
S
I
N
G
E
S
------
M
A
G
K
-
D
------------
L
N
H
A
V
--
L
K
I
R
--
G
K
K
G
S
S
V
S
M
K
I
Q
R
P
G
T
K
---
K
Q
L
S
F
R
I
K
R
A
E
I
P
L
E
--------
T
-
V
-
F
-----
A
--
S
-------------------------------
E
----
K
K
----
V
Q
------------
G
H
S
V
G
Y
I
A
I
S
T
F
S
------------
E
----
H
T
A
E
D
F
A
K
A
L
R
E
L
E
K
K
E
I
E
G
L
V
I
D
V
R
G
N
P
G
G
Y
L
Q
---
S
V
E
E
I
L
K
H
F
V
T
-
K
D
Q
P
-
Y
I
Q
---
I
--
A
E
R
N
------------------------------------------------------
G
D
K
----------
K
R
Y
F
S
T
L
T
H
K
K
A
Y
--
P
V
N
V
I
T
D
K
G
S
A
S
A
S
E
I
L
A
G
A
L
K
E
A
G
H
Y
D
V
V
G
-
D
-
T
S
F
G
K
G
T
V
Q
Q
A
-
V
P
M
G
D
G
S
N
I
---
K
L
T
L
Y
K
W
L
T
P
N
G
N
W
I
H
K
K
-
G
I
E
P
T
I
A
I
--------
K
Q
P
D
Y
F
-
S
-
A
G
-
P
L
Q
L
K
E
P
L
K
V
D
M
-----------------------------------
N
N
E
D
V
K
H
A
Q
V
L
L
K
G
L
S
F
D
P
GR
E
D
G
--
Y
F
S
K
D
M
K
K
A
-
V
M
A
F
Q
D
Q
N
K
L
N
KTGV
I
D
T
R
T
A
E
T
L
N
Q
Q
I
E
K
K
K
S
D
E
K
N
D
L
Q
L
Q
T
A
L
K
S
L
F
----------------------------------------------------
2
PsiBlast_PDB
69.65
27%
59
- C1 -
-
4C2G
-
CTPB_BACSU
A:
[23-436]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
-
V
E
K
-
V
-
D
R
E
K
L
L
E
G
A
I
Q
G
-
M
L
S
T
L
N
D
P
Y
S
V
Y
M
D
K
Q
T
A
K
Q
F
S
D
S
L
D
S
S
F
E
G
I
G
A
E
V
G
M
E
D
G
K
-------
I
I
I
V
S
P
F
K
K
S
P
A
E
K
A
G
-
L
K
P
N
D
E
I
I
---
S
I
N
G
E
S
------
M
A
G
K
-
D
------------
L
N
H
A
V
--
L
K
I
R
--
G
K
K
G
S
S
V
S
M
K
I
Q
R
P
G
T
K
---
K
Q
L
S
F
R
I
K
R
A
E
I
P
L
E
--------
T
-
V
-
F
-----
A
--
S
-------------------------------
E
----
K
K
----
V
Q
------------
G
H
S
V
G
Y
I
A
I
S
T
F
S
------------
E
----
H
T
A
E
D
F
A
K
A
L
R
E
L
E
K
K
E
I
E
G
L
V
I
D
V
R
G
N
P
G
G
Y
L
Q
---
S
V
E
E
I
L
K
H
F
V
T
-
K
D
Q
P
-
Y
I
Q
---
I
--
A
E
R
N
------------------------------------------------------
G
D
K
----------
K
R
Y
F
S
T
L
T
H
K
K
A
Y
--
P
V
N
V
I
T
D
K
G
S
A
A
A
S
E
I
L
A
G
A
L
K
E
A
G
H
Y
D
V
V
G
-
D
-
T
S
F
G
K
G
T
V
Q
Q
A
-
V
P
M
G
D
G
S
N
I
---
K
L
T
L
Y
K
W
L
T
P
N
G
N
W
I
H
K
K
-
G
I
E
P
T
I
A
I
--------
K
Q
P
D
Y
F
-
S
-
A
G
-
P
L
Q
L
K
E
P
L
K
V
D
--------------------------------
M
---
N
N
E
D
V
K
H
A
Q
V
L
L
K
G
L
S
F
D
P
GR
E
D
G
--
Y
F
S
K
D
M
K
K
A
-
V
M
A
F
Q
D
Q
N
K
L
N
KTGV
I
D
T
R
T
A
E
T
L
N
Q
Q
I
E
K
K
K
S
D
E
K
N
D
L
Q
L
Q
T
A
L
K
S
L
F
----------------------------------------------------
1
PsiBlast_PDB
69.24
27%
57
- C1 -
-
4C2D
-
CTPB_BACSU
A:
[23-436]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
-
V
E
K
-
V
-
D
R
E
K
L
L
E
G
A
I
Q
G
-
M
L
S
T
L
N
D
P
Y
S
V
Y
M
D
K
Q
T
A
K
Q
F
S
D
S
L
D
S
S
F
E
G
I
G
A
E
V
G
M
E
D
G
K
-------
I
I
I
V
S
P
F
K
K
S
P
A
E
K
A
G
-
L
K
P
N
D
E
I
I
---
S
I
N
G
E
S
------
M
A
G
K
-
D
------------
L
N
H
A
V
--
L
K
I
R
--
G
K
K
G
S
S
V
S
M
K
I
Q
R
P
G
T
K
---
K
Q
L
S
F
R
I
K
R
A
E
I
P
L
E
--------
T
-
V
-
F
-----
A
--
S
-------------------------------
E
----
K
K
----
V
Q
------------
G
H
S
V
G
Y
I
A
I
S
T
F
S
------------
E
----
H
T
A
E
D
F
A
K
A
L
R
E
L
E
K
K
E
I
E
G
L
V
I
D
V
R
G
N
P
G
G
Y
L
Q
---
S
V
E
E
I
L
K
H
F
V
T
-
K
D
Q
P
-
Y
I
Q
---
I
--
A
E
R
N
------------------------------------------------------
G
D
K
----------
K
R
Y
F
S
T
L
T
H
K
K
A
Y
--
P
V
N
V
I
T
D
K
G
S
A
S
A
S
E
I
L
A
G
A
L
K
E
A
G
H
Y
D
V
V
G
-
D
-
T
S
F
G
K
G
T
V
Q
Q
A
-
V
P
M
G
D
G
S
N
I
---
K
L
T
L
Y
K
W
L
T
P
N
G
N
W
I
H
K
K
-
G
I
E
P
T
I
A
I
--------
K
Q
P
D
Y
F
-
S
-
A
G
-
P
L
Q
L
K
E
P
L
K
V
D
--------------------------------
M
---
N
N
E
D
V
K
H
A
Q
V
L
L
K
G
L
S
F
D
P
GR
E
D
G
--
Y
F
S
K
D
M
K
K
A
-
V
M
A
F
Q
D
Q
N
K
L
N
KTGV
I
D
T
R
T
A
E
T
L
N
Q
Q
I
E
K
K
K
S
D
E
K
N
D
L
Q
L
Q
T
A
L
K
S
L
F
----------------------------------------------------
9
PsiBlast_PDB
68.95
26%
59
- C1 -
-
4C2F
-
CTPB_BACSU
A:
[23-436]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
-
V
E
K
-
V
-
D
R
E
K
L
L
E
G
A
I
Q
G
-
M
L
S
T
L
N
D
P
Y
S
V
Y
M
D
K
Q
T
A
K
Q
F
S
D
S
L
D
S
S
F
E
G
I
G
A
E
V
G
M
E
D
G
K
-------
I
I
I
V
S
P
F
K
K
S
P
A
E
K
A
G
-
L
K
P
N
D
E
I
I
---
S
I
N
G
E
S
------
M
A
G
K
-
D
------------
L
N
H
A
V
--
L
K
I
A
--
G
K
K
G
S
S
V
S
M
K
I
Q
R
P
G
T
K
---
K
Q
L
S
F
R
I
K
R
A
E
I
P
L
E
--------
T
-
V
-
F
-----
A
--
S
-------------------------------
E
----
K
K
----
V
Q
------------
G
H
S
V
G
Y
I
A
I
S
T
F
S
------------
E
----
H
T
A
E
D
F
A
K
A
L
R
E
L
E
K
K
E
I
E
G
L
V
I
D
V
R
G
N
P
G
G
Y
L
Q
---
S
V
E
E
I
L
K
H
F
V
T
-
K
D
Q
P
-
Y
I
Q
---
I
--
A
E
R
N
------------------------------------------------------
G
D
K
----------
K
R
Y
F
S
T
L
T
H
K
K
A
Y
--
P
V
N
V
I
T
D
K
G
S
A
S
A
S
E
I
L
A
G
A
L
K
E
A
G
H
Y
D
V
V
G
-
D
-
T
S
F
G
K
G
T
V
Q
Q
A
-
V
P
M
G
D
G
S
N
I
---
K
L
T
L
Y
K
W
L
T
P
N
G
N
W
I
H
K
K
-
G
I
E
P
T
I
A
I
--------
K
Q
P
D
Y
F
-
S
-
A
G
-
P
L
Q
L
K
E
P
L
K
V
D
M
-----------------------------------
N
N
E
D
V
K
H
A
Q
V
L
L
K
G
L
S
F
D
P
GR
E
D
G
--
Y
F
S
K
D
M
K
K
A
-
V
M
A
F
Q
D
Q
N
K
L
N
KTGV
I
D
T
R
T
A
E
T
L
N
Q
Q
I
E
K
K
K
S
D
E
K
N
D
L
Q
L
Q
T
A
L
K
S
L
F
----------------------------------------------------
3
PsiBlast_PDB
68.23
26%
59
- C1 -
-
4C2E
-
CTPB_BACSU
A:
[65-478]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
-
V
E
K
-
V
-
D
R
E
K
L
L
E
G
A
I
Q
G
-
M
L
S
T
L
N
D
P
Y
S
V
Y
M
D
K
Q
T
A
K
Q
F
S
D
S
L
D
S
S
F
E
G
I
G
A
E
V
G
M
E
D
G
K
-------
I
I
I
V
S
P
F
K
K
S
P
A
E
K
A
G
-
L
K
P
N
D
E
I
I
---
S
I
N
G
E
S
------
M
A
G
K
-
D
------------
L
N
H
A
V
--
L
K
I
R
--
G
K
K
G
S
S
V
S
M
K
I
Q
R
P
G
T
K
---
K
Q
L
S
F
R
I
K
R
A
E
I
P
L
E
--------
T
-
V
-
F
-----
A
--
S
-------------------------------
E
----
K
K
----
V
Q
------------
G
H
S
V
G
Y
I
A
I
S
T
F
S
------------
E
----
H
T
T
E
D
F
A
K
A
L
R
E
L
E
K
K
E
I
E
G
L
V
I
D
V
R
G
N
P
G
G
Y
I
Q
---
S
V
E
E
I
L
K
H
F
V
T
-
K
D
Q
P
-
Y
I
Q
---
I
--
A
E
R
N
------------------------------------------------------
G
D
K
----------
K
R
Y
F
S
T
L
T
H
K
K
A
Y
--
P
V
N
V
I
T
D
K
G
S
A
A
A
S
E
I
L
A
G
A
L
K
E
A
G
H
Y
D
V
V
G
-
D
-
T
S
F
G
K
G
T
V
Q
Q
A
-
V
P
M
G
D
G
S
N
I
---
K
L
T
L
Y
K
W
L
T
P
N
G
N
W
I
H
K
K
-
G
I
E
P
T
I
A
I
--------
K
Q
P
D
Y
F
-
S
-
A
G
-
P
L
Q
L
K
E
P
L
K
V
D
--------------------------------
M
---
N
N
E
D
V
K
H
A
Q
V
L
L
K
G
L
S
F
D
P
GR
E
D
G
--
Y
F
S
K
D
M
K
K
A
-
V
M
A
F
Q
D
Q
N
K
L
N
KTGI
I
D
T
R
T
A
E
T
L
N
Q
Q
I
E
K
K
K
S
D
E
K
N
D
L
Q
L
Q
T
A
L
K
S
L
F
----------------------------------------------------
4
PsiBlast_PDB
67.13
27%
72
- C1 -
-
4C2H
-
?
A:
[65-478]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
-
V
E
K
-
V
-
D
R
E
K
L
L
E
G
A
I
Q
G
-
M
L
S
T
L
N
D
P
Y
S
V
Y
M
D
K
Q
T
A
K
Q
F
S
D
S
L
D
S
S
F
E
G
I
G
A
----
E
Y
G
M
-
E
--
D
G
K
I
I
I
V
S
P
F
K
K
S
P
A
E
K
A
G
-
L
K
P
N
D
E
I
I
---
S
I
N
G
E
S
------
M
A
G
K
-
D
------------
L
N
H
A
V
--
L
K
I
R
--
G
K
K
G
S
S
V
S
M
K
I
Q
R
P
G
T
K
---
K
Q
L
S
F
R
I
K
R
A
E
I
P
L
E
--------
T
-
V
-
F
-----
A
--
S
-------------------------------
E
----
K
K
----
V
Q
------------
G
H
S
V
G
Y
I
A
I
S
T
F
S
------------
E
----
H
T
T
E
D
F
A
K
A
L
R
E
L
E
K
K
E
I
E
G
L
V
I
D
V
R
G
N
P
G
G
Y
I
Q
---
S
V
E
E
I
L
K
H
F
V
T
-
K
D
Q
P
-
Y
I
Q
---
I
--
A
E
R
N
------------------------------------------------------
G
D
K
----------
K
R
Y
F
S
T
L
T
H
K
K
A
Y
--
P
V
N
V
I
T
D
K
G
S
A
S
A
S
E
I
L
A
G
A
L
K
E
A
G
H
Y
D
V
V
G
-
D
-
T
S
F
G
K
G
T
V
Q
Q
A
-
V
P
M
G
D
G
S
N
I
---
K
L
T
L
Y
K
W
L
T
P
N
G
N
W
I
H
K
K
-
G
I
E
P
T
I
A
I
--------
K
Q
P
D
Y
F
-
S
-
A
G
-
P
L
Q
L
K
E
P
L
K
V
D
--------------------------------
M
---
N
N
E
D
V
K
H
A
Q
V
L
L
K
G
L
S
F
D
P
GR
E
D
G
--
Y
F
S
K
D
M
K
K
A
-
V
M
A
F
Q
D
Q
N
K
L
N
KTGI
I
D
T
R
T
A
E
T
L
N
Q
Q
I
E
K
K
K
S
D
E
K
N
D
L
Q
L
Q
T
A
L
K
S
L
F
----------------------------------------------------
27
HHSearch
66.66
22%
-
- C1 -
-
4QL6
-
?
C:
[27-615]
---------------------------------------------
R
Q
D
V
R
K
T
V
D
K
L
V
E
H
H
I
D
T
Q
Q
I
S
P
Y
I
L
S
R
S
L
E
D
Y
V
R
S
F
D
S
H
K
A
Y
L
T
Q
D
E
V
F
S
H
A
FS
E
E
A
T
H
P
L
F
K
Q
Y
Q
E
D
N
F
S
S
F
K
E
L
D
T
C
I
Q
Q
S
I
S
R
A
R
E
W
R
S
S
W
L
T
D
S
I
R
V
I
Q
D
-------
K
K
P
S
A
W
A
S
S
I
E
E
V
K
Q
R
-----
Q
Y
D
L
L
L
S
Y
A
S
I
Y
------------------------
L
V
K
L
C
I
R
Q
I
E
NHE
N
P
Y
I
G
I
N
DH
G
Y
R
-
M
S
P
E
E
-
E
A
N
S
F
H
V
R
I
I
K
S
-
I
A
H
S
L
-
D
A
H
T
A
Y
F
S
Q
E
E
A
L
S
---------------------------------------------------------------------------------------------------------------------------------------------------
R
-----
V
--
D
-------------------------------
V
----
S
Y
----
E
P
Y
---------
G
-
N
G
I
I
G
K
I
T
L
H
S
F
Y
E
----------
Q
V
----
S
S
E
Q
D
L
R
K
A
I
R
E
L
Q
E
K
N
L
L
G
L
V
L
D
I
R
E
N
T
G
G
F
L
S
---
Q
A
I
K
V
S
G
L
-
F
L
-
T
N
G
V
-
V
V
V
---
S
--
R
Y
A
D
------------------------------------------------------
G
S
V
----------
K
R
Y
R
T
I
S
-
P
Q
K
F
Y
D
G
P
L
A
V
L
V
S
K
S
S
A
A
A
A
E
I
V
A
Q
T
L
Q
D
Y
G
V
A
L
I
V
G
-
D
Q
Q
T
Y
G
K
G
T
I
Q
H
Q
T------
D
F
F
---
K
V
T
V
G
R
Y
Y
S
P
S
G
K
S
T
Q
L
E
-
G
V
K
S
D
I
V
I
--------
P
S
R
Y
A
E
D
K
-
L
G
-
E
R
F
L
E
Y
A
L
P
A
D
Q
Y
D
N
V
INDNLGDLDI
N
I
R
P
W
F
Q
K
YYSPHLQK
P
E
L
V
W
R
E
M
L
P
Q
L
A
H
N
S
Q
E
R
L
E
K
N
K
--
N
F
E
--
I
F
V
Q
H
L
K
K
T
N
K
----------------------------------------------------------------------------------------------------
29
HHSearch
65.83
26%
-14
- C1 -
-
4C2H
-
?
B:
[55-395]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
K
A
Y
E
L
I
S
---
N
E
Y
V
E
K
-------
V
---
D
-
R
E
K
L
L
E
G
A
I
Q
G
M
-
L
S
T
L
N
-
D
P
Y
S
V
Y
M
D
K
Q
T
A
K
Q
F
S
D
S
L
D
S
S
F
E
G
I
G
A
E
Y
G
M
---
E
-
D
--
G
-
K
I
I
I
V
S
P
F
K
K
S
P
A
E
K
A
G
-
L
K
P
N
D
E
I
I
---
S
I
N
G
E
S
------
M
A
G
K
-
D
------------
L
N
H
A
V
--
L
K
I
R
--
G
K
K
G
S
S
V
S
M
K
I
Q
R
P
G
T
K
-
K
Q
L
--
S
F
R
I
K
R
A
E
I
P
L
E
--------
T
---------
V
--
F
-------------------------------
A
----
S
E
----
K
K
V
----------
Q
G
H
S
V
G
Y
I
A
I
S
T
F
S
E
H
T
----------------
T
E
D
F
A
K
A
L
R
E
L
E
K
K
E
I
E
G
L
V
I
D
V
R
G
N
P
G
G
Y
I
Q
---
S
V
E
E
I
L
K
H
-
F
V
-
T
K
D
Q
P
Y
I
Q
---
I
--
A
E
R
N
------------------------------------------------------
G
D
K
----------
K
R
Y
F
S
T
L
--
T
H
K
K
A
Y
P
V
N
V
I
T
D
K
G
S
A
S
A
S
E
I
L
A
G
A
L
K
E
A
G
H
Y
D
V
V
G
-
D
-
T
S
F
G
K
G
T
V
Q
Q
A
-
V
P
M
G
D
G
S
N
I
---
K
L
T
L
Y
K
W
L
T
P
N
G
N
W
I
H
K
K
-
G
I
E
P
T
I
A
I
--------
K
Q
P
-
D
Y
F
S
-
A
G
-
P
L
Q
L
K
E
P
L
K
V
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
64.95
25%
-14
- C1 -
-
4C2E
-
CTPB_BACSU
B:
[54-398]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
E
K
A
Y
E
L
I
S
---
N
E
Y
V
E
K
-------
V
---
D
-
R
E
K
L
L
E
G
A
I
Q
G
M
-
L
S
T
L
N
-
D
P
Y
S
V
Y
M
D
K
Q
T
A
K
Q
F
S
D
S
L
D
S
S
F
E
G
I
G
A
E
V
G
M
---
E
-
D
--
G
-
K
I
I
I
V
S
P
F
K
K
S
P
A
E
K
A
G
-
L
K
P
N
D
E
I
I
---
S
I
N
G
E
S
------
M
A
G
K
-
D
------------
L
N
H
A
V
--
L
K
I
R
--
G
K
K
G
S
S
V
S
M
K
I
Q
R
P
G
T
K
-
K
Q
L
--
S
F
R
I
K
R
A
E
I
P
L
E
--------
T
---------
V
--
F
-------------------------------
A
----
S
E
----
K
K
----------
V
Q
G
H
S
V
G
Y
I
A
I
S
T
F
S
E
H
T
----------------
T
E
D
F
A
K
A
L
R
E
L
E
K
K
E
I
E
G
L
V
I
D
V
R
G
N
P
G
G
Y
I
Q
---
S
V
E
E
I
L
K
H
-
F
V
-
T
K
D
Q
P
Y
I
Q
---
I
--
A
E
R
N
------------------------------------------------------
G
D
K
----------
K
R
Y
F
S
T
L
--
T
H
K
K
A
Y
P
V
N
V
I
T
D
K
G
S
A
A
A
S
E
I
L
A
G
A
L
K
E
A
G
H
Y
D
V
V
G
-
D
-
T
S
F
G
K
G
T
V
Q
Q
A
-
V
P
M
G
D
G
S
N
I
---
K
L
T
L
Y
K
W
L
T
P
N
G
N
W
I
H
K
K
-
G
I
E
P
T
I
A
I
--------
K
Q
P
-
D
Y
F
S
-
A
G
-
P
L
Q
L
K
E
P
L
K
V
D
M
N
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
63.74
22%
-
- C1 -
-
4QL6
-
?
B:
[27-615]
---------------------------------------------
R
Q
D
V
R
K
T
V
D
K
L
V
E
H
H
I
D
T
Q
Q
I
S
P
Y
I
L
S
R
S
L
E
D
Y
V
R
S
F
D
S
H
K
A
Y
L
T
Q
D
E
V
F
S
H
A
FS
E
E
A
T
H
P
L
F
K
Q
Y
Q
E
D
N
F
S
S
F
K
E
L
D
T
C
I
Q
Q
S
I
S
R
A
R
E
W
R
S
S
W
L
T
D
S
I
R
V
I
Q
D
A
M
S
H
T
I
E
K
K
P
S
A
W
A
S
S
I
E
E
V
K
Q
R
-----
Q
Y
D
L
L
L
S
Y
A
S
I
Y
L
-------
Y
Q
G
K
E
---------
H
G
L
V
K
L
C
I
R
Q
I
E
N
H
E
N
P
Y
I
G
I
N
DHG
Y
R
-
M
S
P
E
E
-
E
A
N
S
F
H
V
R
I
I
K
S
-
I
A
H
S
L
-
D
A
H
T
A
Y
F
S
Q
E
E
A
L
S
---------------------------------------------------------------------------------------------------------------------------------------------------
R
-----
V
--
D
-------------------------------
V
----
S
Y
----
E
P
Y
---------
G
-
N
G
I
I
G
K
I
T
L
H
S
F
Y
E
G
E
-------
N
Q
V
----
S
S
E
Q
D
L
R
K
A
I
R
E
L
Q
E
K
N
L
L
G
L
V
L
D
I
R
E
N
T
G
G
F
L
S
---
Q
A
I
K
V
S
G
L
-
F
L
-
T
N
G
V
-
V
V
V
---
S
--
R
Y
A
D
------------------------------------------------------
G
S
V
----------
K
R
Y
R
T
I
S
-
P
Q
K
F
Y
D
G
P
L
A
V
L
V
S
K
S
S
A
A
A
A
E
I
V
A
Q
T
L
Q
D
Y
G
V
A
L
I
V
G
-
D
Q
Q
T
Y
G
K
G
T
I
Q
H
Q
T------
D
F
F
---
K
V
T
V
G
R
Y
Y
S
P
S
G
K
S
T
Q
L
E
-
G
V
K
S
D
I
V
I
--------
P
S
R
Y
A
E
D
K
-
L
G
-
E
R
F
L
E
Y
A
L
P
A
D
Q
Y
D
N
V
INDNLGDLDI
N
I
R
P
W
F
Q
K
YYSPHLQK
P
E
L
V
W
R
E
M
L
P
Q
L
A
H
N
S
Q
E
R
L
E
K
N
K
--
N
F
E
--
I
F
V
Q
H
L
K
K
T
N
K
----------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
63.18
29%
-0
- C1 -
-
1FC9
-
CTPA_TETOB
A:
[109-438]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
---
E
T
Y
L
K
K
E
---
P
M
-
D
R
R
-
A
-
Q
T
Y
D
A
I
R
K
L
L
A
V
-
L
---
D
-
D
P
F
T
R
F
L
E
P
S
R
L
A
A
L
R
R
G
T
A
G
S
V
T
G
V
G
L
E
I
T
Y
D
G
G
S
-
G
--
K
-
D
V
V
V
L
T
P
A
P
G
G
P
A
E
K
A
G
-
A
R
A
G
D
V
I
V
---
T
V
D
G
T
A
-
V
K
-----
G
L
-
S
------------
L
Y
D
V
S
--
D
L
L
Q
--
G
E
A
D
S
Q
V
E
V
V
L
H
A
P
G
A
P
--
S
N
T
R
T
L
Q
L
T
R
Q
K
V
T
I
N
--------
P
-
V
-
T
-----
F
--
T
-------------------------------
T
----
C
S
NVAA
A
A
L
P
P
------
G
A
A
K
Q
Q
L
G
Y
V
R
L
A
T
F
--
N
S
N
T
T
A
A
A
Q
Q
--------------
A
F
T
E
L
S
K
Q
G
V
A
G
L
V
L
D
I
R
N
N
G
G
G
L
F
P
A
G
V
N
V
A
R
M
L
----
V
-
D
R
G
D
-
L
V
L
---
I
--
A
D
S
Q
------------------------------------------------------
G
I
R
----------
D
I
Y
S
-
A
D
G
N
S
I
D
S
A
T
P
L
V
V
L
V
N
R
G
T
A
S
A
S
E
V
L
A
G
A
L
K
D
S
K
R
G
L
I
A
G
-
E
-
R
T
F
G
K
G
L
I
Q
T
V
-
V
D
-
L
S
D
G
S
G
---
V
A
V
T
V
A
R
Y
Q
T
P
A
G
V
D
I
N
K
I
G
V
S
P
D
V
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
62.83
29%
-3
- C1 -
-
1FCF
-
CTPA_TETOB
A:
[33-362]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
---
E
T
Y
L
K
K
E
---
P
M
-
D
R
R
-
A
-
Q
T
Y
D
A
I
R
K
L
L
A
V
-
L
---
D
-
D
P
F
T
R
F
L
E
P
S
R
L
A
A
L
R
R
G
T
A
G
S
V
T
G
V
G
L
E
I
T
Y
D
G
G
S
-
G
--
K
-
D
V
V
V
L
T
P
A
P
G
G
P
A
E
K
A
G
-
A
R
A
G
D
V
I
V
---
T
V
D
G
T
A
-
V
K
-----
G
L
-
S
------------
L
Y
D
V
S
--
D
L
L
Q
--
G
E
A
D
S
Q
V
E
V
V
L
H
A
P
G
A
P
--
S
N
T
R
T
L
Q
L
T
R
Q
K
V
T
I
N
--------
P
-
V
-
T
-----
F
--
T
-------------------------------
T
----
C
S
NVAA
A
A
L
P
P
------
G
A
A
K
Q
Q
L
G
Y
V
R
L
A
T
F
--
N
S
N
T
T
A
A
A
Q
Q
--------------
A
F
T
E
L
S
K
Q
G
V
A
G
L
V
L
D
I
R
N
N
G
G
G
L
F
P
A
G
V
N
V
A
R
M
L
----
V
-
D
R
G
D
-
L
V
L
---
I
--
A
D
S
Q
------------------------------------------------------
G
I
R
----------
D
I
Y
S
-
A
D
G
N
S
I
D
S
A
T
P
L
V
V
L
V
N
R
G
T
A
S
A
S
E
V
L
A
G
A
L
K
D
S
K
R
G
L
I
A
G
-
E
-
R
T
F
G
K
G
L
I
Q
T
V
-
V
D
-
L
S
D
G
S
G
---
V
A
V
T
V
A
R
Y
Q
T
P
A
G
V
D
I
N
K
I
G
V
S
P
D
V
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
62.06
29%
1
- C1 -
-
1FC7
-
CTPA_TETOB
A:
[109-438]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
---
E
T
Y
L
K
K
E
---
P
M
-
D
R
R
-
A
-
Q
T
Y
D
A
I
R
K
L
L
A
V
-
L
---
D
-
D
P
F
T
R
F
L
E
P
S
R
L
A
A
L
R
R
G
T
A
G
S
V
T
G
V
G
L
E
I
T
Y
D
G
G
S
-
G
--
K
-
D
V
V
V
L
T
P
A
P
G
G
P
A
E
K
A
G
-
A
R
A
G
D
V
I
V
---
T
V
D
G
T
A
-
V
K
-----
G
L
-
S
------------
L
Y
D
V
S
--
D
L
L
Q
--
G
E
A
D
S
Q
V
E
V
V
L
H
A
P
G
A
P
--
S
N
T
R
T
L
Q
L
T
R
Q
K
V
T
I
N
--------
P
-
V
-
T
-----
F
--
T
-------------------------------
T
----
C
S
NVAA
A
A
L
P
P
------
G
A
A
K
Q
Q
L
G
Y
V
R
L
A
T
F
--
N
S
N
T
T
A
A
A
Q
Q
--------------
A
F
T
E
L
S
K
Q
G
V
A
G
L
V
L
D
I
R
N
N
G
G
G
L
F
P
A
G
V
N
V
A
R
M
L
----
V
-
D
R
G
D
-
L
V
L
---
I
--
A
D
S
Q
------------------------------------------------------
G
I
R
----------
D
I
Y
S
-
A
D
G
N
S
I
D
S
A
T
P
L
V
V
L
V
N
R
G
T
A
S
A
S
E
V
L
A
G
A
L
K
D
S
K
R
G
L
I
A
G
-
E
-
R
T
F
G
K
G
L
I
Q
T
V
-
V
D
-
L
S
D
G
S
G
---
V
A
V
T
V
A
R
Y
Q
T
P
A
G
V
D
I
N
K
I
G
V
S
P
D
V
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
62.03
24%
25
- C1 -
-
1FC6
-
CTPA_TETOB
A:
[78-463]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
S
E
Q
L
L
F
L
E
A
W
R
A
V
D
R
A
Y
V
D
K
S
F
N
G
Q
S
W
F
K
L
R
---
E
T
Y
L
K
K
---------
E
-
P
M
D
R
R
A
Q
T
Y
D
A
I
R
K
M
L
A
V
L
D
-
D
P
F
T
R
F
L
E
P
S
R
L
A
A
L
R
R
G
T
A
G
S
V
T
G
V
G
L
E
I
T
Y
D
G
G
S
-
G
--
K
-
D
V
V
V
L
T
P
A
P
G
G
P
A
E
K
A
G
-
A
R
A
G
D
V
I
V
---
T
V
D
G
T
A
-------
V
K
G
M
S
------------
L
Y
D
V
S
--
D
L
L
Q
--
G
E
A
D
S
Q
V
E
V
V
L
H
A
P
G
-
A
-
P
S
N
T
R
T
L
Q
L
T
R
Q
K
V
T
I
N
--------
P
-
V
-
T
-----
F
--
T
-------------------------------
T
C
S
NV
A
A
----
A
A
L
P
P
------
G
A
A
K
Q
Q
L
G
Y
V
R
L
A
T
F
N
------------
S
----
N
T
T
A
A
A
Q
Q
A
F
T
E
L
S
K
Q
G
V
A
G
L
V
L
D
I
R
N
N
G
G
G
L
F
P
---
A
G
V
N
V
A
-
R
M
L
V
-
D
R
G
D
-
L
V
L
---
I
--
A
D
S
Q
------------------------------------------------------
G
I
R
----------
D
I
Y
S
-
A
D
G
N
S
I
D
S
A
T
P
L
V
V
L
V
N
R
G
T
A
S
A
S
E
V
L
A
G
A
L
K
D
S
K
R
G
L
I
A
G
-
E
-
R
T
F
G
K
G
L
I
Q
T
V
-
V
D
L
S
D
G
S
G
V
---
A
V
T
V
A
R
Y
Q
T
P
A
G
V
D
I
N
K
I
-
G
V
S
P
D
V
Q
L
DPEVLPTD
L
E
G
V
C
R
-
V
-
L
G
-
S
D
A
A
P
R
L
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
61.89
20%
-
- C1 -
-
4QL6
-
?
A:
[22-644]
---------------------------------------
A
E
P
L
R
R
Q
D
V
R
K
T
V
D
K
L
V
-
E
H
H
I
D
T
Q
Q
I
S
P
Y
I
L
S
R
S
L
E
D
Y
V
R
S
F
D
S
H
K
A
Y
L
T
Q
D
E
V
F
S
H
----
A
F
S
E
E
A
T
H
P
L
F
K
Q
Y
Q
E
D
N
F
-------
S
S
F
K
E
L
D
T
C
I
Q
Q
S
I
S
R
A
R
E
W
R
S
S
W
L
T
D
S
I
R
V
I
Q
--------------------
D
A
K
P
S
A
W
A
S
S
I
E
E
V
K
Q
R
Q
Y
D
L
L
L
S
Y
A
S
I
Y
L
L
C
I
R
Q
I
E
N
H
E
N
P
Y
I
---
G
I
N
D
H
G
Y
---
R
M
-
S
P
E
-
E
-
E
A
N
S
F
H
V
R
I
I
K
S
-
I
A
H
S
L
-
D
A
H
T
A
Y
F
S
Q
E
E
A
L
R
V
D
V
S
Y
E
P
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
N
G
I
I
G
K
I
T
L
H
S
F
Y
---------
E
N
Q
V
----
S
S
E
Q
D
L
R
K
A
I
R
E
L
Q
E
K
N
L
L
G
L
V
L
D
I
R
E
N
T
G
G
F
L
S
---
Q
A
I
K
V
S
G
L
-
F
L
-
T
N
G
V
-
V
V
V
---
S
--
R
Y
A
D
------------------------------------------------------
G
S
V
----------
K
R
Y
R
T
I
S
P
-
Q
K
F
Y
D
G
P
L
A
V
L
V
S
K
S
S
A
A
A
A
E
I
V
A
Q
T
L
Q
D
Y
G
V
A
L
I
V
G
D
Q
-
Q
T
Y
G
K
G
T
I
Q
H
Q
-
T
D
-----
F
F
---
K
V
T
V
G
R
Y
Y
S
P
S
G
K
S
T
Q
L
E
-
G
V
K
S
D
I
V
I
--------
P
S
R
Y
A
E
D
K
-
L
G
-
E
R
F
L
E
Y
A
L
P
A
D
Q
Y
D
N
V
----------
I
N
D
N
L
G
----------
D
L
---
D
I
---------------------------------
N
I
R
P
W
F
Q
K
Y
Y
S
P
----
H
L
Q
K
P
E
L
V
W
R
--
E
M
L
P
Q
L
A
H
N
S
Q
E
R
L
E
K
------------
N
K
N
F
E
I
F
V
Q
H
L
K
K
-
T
N
K
Q
D
R
S
F
G
S
N
D
L
Q
M
E
E
S
V
N
I
V
K
D
M
I
L
L
K
S
I
S
10
PsiBlast_PDB
59.99
28%
10
- C1 -
-
1FC6
-
CTPA_TETOB
A:
[109-438]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
---
E
T
Y
L
K
K
E
---
P
M
-
D
R
R
-
A
-
Q
T
Y
D
A
I
R
K
M
L
A
V
-
L
---
D
-
D
P
F
T
R
F
L
E
P
S
R
L
A
A
L
R
R
G
T
A
G
S
V
T
G
V
G
L
E
I
T
Y
D
G
G
S
-
G
--
K
-
D
V
V
V
L
T
P
A
P
G
G
P
A
E
K
A
G
-
A
R
A
G
D
V
I
V
TVD
G
T
A
V
K
G
-
M
S
L
Y
D
V
S
D
-----------------------
L
L
Q
--
G
E
A
D
S
Q
V
E
V
V
L
H
A
P
G
A
P
--
S
N
T
R
T
L
Q
L
T
R
Q
K
V
T
I
N
--------
P
-
V
-
T
-----
F
--
T
-------------------------------
T
----
C
S
NVAA
A
A
L
P
P
------
G
A
A
K
Q
Q
L
G
Y
V
R
L
A
T
F
--
N
S
N
T
T
A
A
A
Q
Q
--------------
A
F
T
E
L
S
K
Q
G
V
A
G
L
V
L
D
I
R
N
N
G
G
G
L
F
P
---
A
G
V
N
V
A
R
M
-
L
V
-
D
R
G
D
-
L
V
L
---
I
--
A
D
S
Q
------------------------------------------------------
G
I
R
----------
D
I
Y
S
-
A
D
G
N
S
I
D
S
A
T
P
L
V
V
L
V
N
R
G
T
A
S
A
S
E
V
L
A
G
A
L
K
D
S
K
R
G
L
I
A
G
-
E
-
R
T
F
G
K
G
L
I
Q
T
V
-
V
D
-
L
S
D
G
S
G
---
V
A
V
T
V
A
R
Y
Q
T
P
A
G
V
D
I
N
K
I
G
V
S
P
D
V
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
57.22
24%
17
- C1 -
-
1FCF
-
CTPA_TETOB
A:
[30-376]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
F
K
L
R
---
E
T
Y
L
K
K
E
-------
P
M
-
D
-
R
R
A
Q
T
Y
D
A
I
R
K
L
-
L
A
V
L
D
-
D
P
F
T
R
F
L
E
P
S
R
L
A
A
L
R
R
G
T
A
G
S
V
T
G
V
G
L
E
I
T
Y
---
D
-
G
G
S
G
K
D
V
V
V
L
T
P
A
P
G
G
P
A
E
K
A
G
-
A
R
A
G
D
V
I
V
---
T
V
D
G
T
A
V
K
G
L
S
-------------------
L
Y
D
V
S
--
D
L
L
Q
--
G
E
A
D
S
Q
V
E
V
V
L
H
A
P
G
A
P
S
N
T
R
--
T
L
Q
L
T
R
Q
K
V
T
I
N
--------
P
-
V
T
F
T
T
C
S
N
V
--
A
-------------------------------
A
----
A
A
----
L
P
P
G
A
--------
A
K
Q
Q
L
G
Y
V
R
L
A
T
F
N
S
N
T
----------------
T
A
A
A
Q
Q
A
F
T
E
L
S
K
Q
G
V
A
G
L
V
L
D
I
R
N
N
G
G
G
L
F
P
---
A
G
V
N
V
A
R
M
-
L
V
-
D
R
G
D
-
L
V
L
---
I
--
A
D
S
Q
------------------------------------------------------
G
I
R
----------
D
I
Y
S
A
D
G
-
N
S
I
D
S
A
T
P
L
V
V
L
V
N
R
G
T
A
S
A
S
E
V
L
A
G
A
L
K
D
S
K
R
G
L
I
A
G
-
E
-
R
T
F
G
K
G
L
I
Q
T
V
-
V
D
L
S
D
G
S
G
V
---
A
V
T
V
A
R
Y
Q
T
P
A
G
V
D
I
N
K
I
-
G
V
S
P
D
V
Q
L
--------
D
P
E
V
L
P
-------
T
D
L
E
G
V
C
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
57.04
25%
15
- C1 -
-
1FC6
-
CTPA_TETOB
A:
[120-453]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-
R
R
A
Q
T
Y
D
A
I
R
K
M
-
L
A
V
L
D
-
D
P
F
T
R
F
L
E
P
S
R
L
A
A
L
R
R
G
T
A
G
S
V
T
G
V
G
L
E
I
T
Y
---
D
-
G
GS
G
K
D
V
V
V
L
T
P
A
P
G
G
P
A
E
K
A
G
-
A
R
A
G
D
V
I
V
---
T
V
D
G
T
A
V
K
G
M
S
-------------------
L
Y
D
V
S
--
D
L
L
Q
--
G
E
A
D
S
Q
V
E
V
V
L
H
A
P
G
A
P
S
N
T
R
--
T
L
Q
L
T
R
Q
K
V
T
I
N
--------
P
V
T
-
F
T
T
C
S
N
V
--
A
-------------------------------
A
----
A
A
----
L
P
P
G
--------
A
A
K
Q
Q
L
G
Y
V
R
L
A
T
F
N
S
N
T
----------------
T
A
A
A
Q
Q
A
F
T
E
L
S
K
Q
G
V
A
G
L
V
L
D
I
R
N
N
G
G
G
L
F
P
---
A
G
V
N
V
A
R
M
-
L
V
-
D
R
G
D
-
L
V
L
---
I
--
A
D
S
Q
------------------------------------------------------
G
I
R
----------
D
I
Y
S
A
D
G
-
N
S
I
D
S
A
T
P
L
V
V
L
V
N
R
G
T
A
S
A
S
E
V
L
A
G
A
L
K
D
S
K
R
G
L
I
A
G
-
E
-
R
T
F
G
K
G
L
I
Q
T
V
-
V
D
L
S
D
G
S
G
V
---
A
V
T
V
A
R
Y
Q
T
P
A
G
V
D
I
N
K
I
-
G
V
S
P
D
V
Q
L
--------
D
P
E
V
L
P
-------
T
D
L
E
G
V
C
R
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
54.77
18%
24
- C1 -
-
3DPN
-
Y858_CHLTR
A:
[85-597]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
-
S
T
S
F
C
Q
Q
V
L
A
D
F
-
I
G
G
L
N
-
D
F
H
A
G
V
T
F
F
A
I
E
----------
S
A
Y
L
P
Y
T
V
Q
K
---
S
S
D
--
G
-
R
F
Y
F
V
D
I
M
T
F
----
S
S
-
E
I
R
V
G
D
E
L
L
---
E
V
D
G
A
P
V
Q
D
V
L
A
T
L
Y
G
-
S
NHKGT
A
A
E
E
S
A
A
L
R
T
L
F
SR
M
A
S
L
GH
K
V
P
S
G
R
T
T
L
K
I
R
R
P
F
G
--
T
T
R
--
E
V
R
V
K
W
R
Y
V
P
E
G
SLFYSPMV
P
H
F
-
W
-----
A
E
L
R
N
H
Y
A
T
S
GLKSGYNIGSTDGFLPVIGPVIWES
E
----
G
L
----
F
R
A
Y
I
S
S
V
T
D
G
D
G
K
S
H
K
V
G
F
L
R
I
P
T
Y
S
W
Q
D
M
E
-----
D
F
D
PSGP
P
P
W
E
E
F
A
K
I
I
Q
V
F
-
S
S
N
T
E
A
L
I
I
D
Q
T
N
N
P
G
G
S
V
L
---
Y
L
Y
A
L
L
S
M
-
L
T
-
D
R
P
L
-
E
L
P
K
H
R
M
I
L
T
Q
D
E
V
V
D
A
L
D
W
L
T
L
L
E
NVDT
N
V
E
S
R
L
A
L
GDNMEG
Y
T
V
D
L
Q
V
A
E
Y
L
K
S
F
G
R
Q
V
L
N
C
W
S
K
G
D
I
ELSTPIPLFG
F
E
K
I
H
P
H
-
P
R
V
Q
Y
S
K
P
I
C
V
L
I
N
E
Q
D
F
A
C
A
D
F
F
P
V
V
L
K
D
N
D
R
A
L
I
V
G
-
T
-
R
T
A
G
A
G
G
F
V
F
N
-
V
Q
F
P
N
R
T
G
I
K
T
C
S
L
T
G
S
L
A
V
R
E
H
G
A
F
I
E
N
I
-
G
V
E
P
H
I
D
L
--------
P
F
T
A
N
D
I
R
Y
K
G
Y
S
E
Y
L
D
K
V
K
K
L
V
C
Q
L
I
N
----------
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------