@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VMS3: (2017-11-10 )
MAKILVTGGAGYIGSHTCVELLEAGHEVIVFDNLSNSSKESLNRVQEITHKSLTFVEGDIRNSGELDQVFQEHAIDAVIHFAGLKAVGESQEKPLIYFDNNIAGSIQLVKSMEKAGVYTLVFSSSATVYDEANTSPLNEEMPTGMPSNNYGYTKLIVEQLLQKLSVADSKWSIALLRYFNPVGAHKSGRIGEDPQGIPNNLMPYVTQVAVGRREKLSIYGNDYDTIDGTGVRDYIHVVDLANAHLCALNNRLQAQGCRAWNIGTGNGSSVLQVKNTFEQVNGVPVAFEFAPRRAGDVATSFADNARAVAELGWKPQYGLEDMLKDSWNWQKQNPNGYN
Atome Classification :
(48 SA)
.........10........20........30.......------.------40........50........60........70...-.....80........90........100.......110.......120.......130----.----......140.......150.......160......-------------.170........180.......190--.......200.......210.......220.......230.......240.......250....----.-----...260.......270.......280.......290.......300.......310.......320.......330......-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
A
K
I
L
V
TGGAGYI
G
S
H
T
C
V
E
L
L
EAG
H
E
V
I
V
FDNLSNS
S
------
K
------
E
S
L
N
R
V
Q
E
I
T
H
KS
L
T
F
V
EGDIRNSG
E
L
D
Q
V
F
Q
E
H
A
-
I
D
A
V
I
H
F
A
G
L
K
AVGESQEK
P
L
I
Y
FDNNIA
G
S
I
Q
L
V
K
S
M
E
KA
G
V
Y
T
L
V
FSSS
A
T
V
YDEA----N----TSPLNEEMPTGMPSNNY
G
Y
T
K
L
I
V
E
Q
L
L
Q
K
LSVAD-------------SK-
W
S
I
A
L
L
R
YFNPVGAHKSGRIGE--DPQGIP
N
N
L
M
P
Y
V
T
Q
V
AVGR
R
E
K
L
S
I
YGNDYDTIDGTG
V
R
D
Y
I
H
V
V
DLAN
A
H
L
C
ALNN-
R
L
Q
AQ----G-----C
R
A
W
NIGTGNGS
S
V
L
Q
V
K
N
T
F
E
QVNG
V
P
V
A
F
E
FAPRRAG
D
V
A
T
S
FAD
N
A
R
A
V
A
ELGWKPQY
G
L
E
D
M
L
K
DSWNWQKQNPNGYN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
96.27
55%
-77
- C1 -
-
1KVT
3
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
V
A
T
V
Y
G
D
N
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
96.24
55%
-84
- C1 -
-
1LRK
3
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
N
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
C
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
HHSearch
96.11
55%
-79
* C1 *
-
1A9Y
2
GALE_ECOLI
A:
[1-336]
-
M
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
A
A
T
V
Y
G
D
Q
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
F
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
96.10
55%
-79
- C1 -
-
1XEL
4
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
N
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
95.71
55%
-77
- C1 -
-
1NAI
4
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
N
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
95.29
55%
-79
- C1 -
-
1KVU
4
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
Q
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
F
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
95.16
55%
-77
- C1 -
-
1UDB
4
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
N
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
95.11
54%
-79
- C1 -
-
1A9Z
3
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
A
A
T
V
Y
G
D
N
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
F
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
95.10
55%
-78
- C1 -
-
1NAH
4
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
N
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
94.86
55%
-79
- C1 -
-
1LRL
3
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
N
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
C
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
94.81
54%
-78
- C1 -
-
1A9Y
2
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
A
A
T
V
Y
G
D
Q
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
F
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
94.58
55%
-78
- C1 -
-
1UDC
6
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
Q
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
94.53
55%
-80
- C1 -
-
1KVS
3
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
T
A
T
V
Y
G
D
N
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
94.53
55%
-78
- C1 -
-
2UDP
3
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
Q
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
65
HHSearch
94.51
55%
-75
- C1 -
-
5GY7
3
GALE_ECOLI
A:
[1-336]
-
M
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
Q
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
I
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
94.43
55%
-80
- C1 -
-
2UDP
2
GALE_ECOLI
B:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
Q
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
94.31
55%
-78
- C1 -
-
1KVR
4
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
A
A
T
V
Y
G
D
Q
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
94.31
55%
-78
- C1 -
-
1LRJ
3
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
N
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
94.23
55%
-78
- C1 -
-
1KVQ
3
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
A
A
T
V
Y
G
D
N
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
93.76
55%
-74
- C1 -
-
5GY7
3
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
Q
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
I
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
93.05
55%
-76
- C1 -
-
5GY7
2
GALE_ECOLI
B:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
Q
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
I
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
93.02
55%
-76
- C1 -
-
1UDA
4
GALE_ECOLI
A:
[2-336]
--
R
V
L
V
T
G
G
S
G
Y
I
G
S
H
T
C
V
Q
L
L
Q
N
G
H
D
V
I
I
L
D
N
L
C
N
S
K
------
R
------
S
V
L
P
V
I
E
R
L
G
G
K
H
P
T
F
V
E
G
D
I
R
N
E
A
L
M
T
E
I
L
H
D
H
A
-
I
D
T
V
I
H
F
A
G
L
K
A
V
G
E
S
V
Q
K
P
L
E
Y
Y
D
N
N
V
N
G
T
L
R
L
I
S
A
M
R
A
A
N
V
K
N
F
I
F
S
S
S
A
T
V
Y
G
D
N
----
P
----
K
I
P
Y
V
E
S
F
P
T
G
T
P
Q
S
P
Y
G
K
S
K
L
M
V
E
Q
I
L
T
D
L
Q
K
A
Q
-------------
P
D
-
W
S
I
A
L
L
R
Y
F
N
P
V
G
A
H
P
S
G
D
M
G
E
--
D
P
Q
G
I
P
N
N
L
M
P
Y
I
A
Q
V
A
V
G
R
R
D
S
L
A
I
F
G
N
D
Y
P
T
E
D
G
T
G
V
R
D
Y
I
H
V
M
D
L
A
D
G
H
V
V
A
M
E
K
-
L
A
N
K
P
----
G
-----
V
H
I
Y
N
L
G
A
G
V
G
N
S
V
L
D
V
V
N
A
F
S
K
A
C
G
K
P
V
N
Y
H
F
A
P
R
R
E
G
D
L
P
A
Y
W
A
D
A
S
K
A
D
R
E
L
N
W
R
V
T
R
T
L
D
E
M
A
Q
D
T
W
H
W
Q
S
R
H
P
Q
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
92.56
52%
-89
- C1 -
-
3ENK
2
?
A:
[8-340]
---
I
L
V
T
G
G
A
G
Y
I
G
S
H
T
A
V
E
L
L
A
H
G
Y
D
V
V
I
A
D
N
L
V
N
S
K
------
R
------
E
A
I
A
R
I
E
K
I
T
G
K
T
P
A
F
H
E
T
D
V
S
D
E
R
A
L
A
R
I
F
D
A
H
P
-
I
T
A
A
I
H
F
A
A
L
K
A
V
G
E
S
V
A
K
P
I
E
Y
Y
R
N
N
L
D
S
L
L
S
L
L
R
V
M
R
E
R
A
V
K
R
I
V
F
S
S
S
A
T
V
Y
G
V
P
----
E
----
R
S
P
I
D
E
T
F
P
L
S
A
-
T
N
P
Y
G
Q
T
K
L
M
A
E
Q
I
L
R
D
V
E
A
A
D
-------------
P
S
-
W
R
V
A
T
L
R
Y
F
N
P
V
G
A
H
E
S
G
L
I
G
E
--
D
P
A
G
I
P
N
N
L
M
P
Y
V
A
Q
V
A
V
G
K
L
E
K
L
R
V
F
G
S
D
Y
P
T
P
D
G
T
G
V
R
D
Y
I
H
V
V
D
L
A
R
G
H
I
A
A
L
D
A
-
L
E
R
R
D
----
A
-----
S
L
T
V
N
L
G
T
G
R
G
Y
S
V
L
E
V
V
R
A
F
E
K
A
S
G
R
A
V
P
Y
E
L
V
A
R
R
P
G
D
V
A
E
C
Y
A
N
P
A
A
A
A
E
T
I
G
W
K
A
E
R
D
L
E
R
M
C
A
D
H
W
R
W
Q
E
N
N
P
R
G
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------