@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VPJ7: (2017-11-21 )
MRVRRPTMSFAFWSRLKALVRKETKQLLRDKGSLGIGLVLPVILILLFGYGLSFDLNQARVGVVVDQSSPQVNQVLAGLNGSRYLTSLEFRNLPEAEQAIRNGKIDAILHLPSDFANQVQQGNAKVQLLLNGRSTTIATALEGYVAGALATAPSIQIDRSPILASASAVKIEQRIWFNESGNSTWFLVPGLMILILTLIGAFLTGLLIARERERGTLEALFVTPVRPFEIVLAKLIPYVVVGMIDIVICIVAAHFIFEVPMRGSLFSILFASFLYLIVSLLLGLTISGFAQSQFQASQIALLASFMPALMLSGFVFDTRNLPLVVQIISQLLPATHFMVLIKTLFMGGDDWKLWFKECGILLGYIVVLICAVNFSLKKRLR
Atome Classification :
(20 SA)
---------------------.........10...----------.....20------------........30........40........50---........60......--..70........80-.......-----.--90........----100.....-----..110.-......120-.-.--....--.130.......140---------------..----.----.....---150.---.-----------.....160.......170---------------...------.....---180.......190----....-...200.-......210...-....220....-..-..230......-----.-240-----.......250.......260..------------......270.......280--------.......290.......300--------------.........310..-......320.......330....--....340..-------....----...350-----------------------.--------------------------------.-......360.....----.-----.370.-......380--
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------MRVRRP
T
M
S
F
A
F
W
S
----------
R
L
K
A
L
V
R
------------
K
E
T
K
Q
L
L
R
DKGSL
G
I
G
L
V
L
P
V
I
L
I
L
L
F
GYG---L
S
F
DLNQ
A
R
V
G
V
V
V
DQ--SSP
Q
V
N
Q
V
L
AGLNG-S
R
Y
L
T
S
L-----E--FRNLP
E
A
E
Q
A
----
I
RNGK
I
D
A
-----
I
L
HL
P
S
-
D
F
A
N
Q
V
QQG-N-
A
--
K
V
Q
L
--
L
LNGRS
T
T
I
A
T
A
L
----------------
E
G
----
Y
----
V
AGAL---ATA
P
---
S
-----------
I
Q
IDRSPILASA
S
A
V
K
I
----------------
E
Q
R
------
I
W
FNE---SG
N
S
T
W
F
L
V
P
G
L
M
----
I
L
I
L
-
T
L
I
G
A
F
L
-
T
G
L
L
I
A
RERERG-
T
L
E
A
L
-
F
VTPV-
R
P
-
F
E
I
V
L
A
K
L
I
P
Y
-----
V
-
V
V
G
-----
M
I
D
I
V
I
C
I
V
A
A
H
F
I
F
EVPM-RG------------
S
L
F
S
I
L
F
A
S
F
L
Y
L
I
V
S
L
L
L
--------
G
L
T
I
S
G
F
A
Q
S
QF
Q
A
S
Q
I
A
----------------
L
L
A
S
F
M
P
A
L
M
L
-
S
G
-
F
V
FDTRN
L
P
L
V
V
Q
I
I
S
Q
-
L
L
P
A
T
--
H
F
M
V
L
--
I
K
-------
T
L
FM----GG
D
D
W
------------------------
K
--------------------------------
L
-
W
F
K
E
C
G
I
L
L
G
Y
I
V
V
----
L
-----
I
C
AV
N
-
F
S
L
K
K
RLR---
38
Fugue
58.75
18%
-17
* C5 *
-
5TZJ
1
?
A:
[1-349]
---------------------
M
K
F
S
V
I
V
P
T
Y
N
S
E
K
----------
Y
I
T
E
L
L
N
------------
S
L
A
K
Q
-----------------------------
D
F
P
K
T
E
F
E
V
V
V
V
D
D
C
--
S
T
D
Q
T
L
Q
I
V
E
K
Y
R
N
-
K
L
N
L
K
V
S
-----
Q
--
L
E
T
N
S
G
G
P
G
K
----
P
R
N
V
A
L
K
Q
AEGE
F
V
L
F
V
D
S
D
D
Y
I
N
K
E
T
L
K
-
D
-
A
--
A
A
F
I
--
D
E
H
-
H
S
D
V
L
L
I
K
M
----------------
K
G
----
V
NG
R
G
V
P
Q
S
M
FK-
E
T
A
P
---
E
-----------
V
T
L
L
N
S
R
I
I
Y
T
L
S
P
T
K
I
YR
T
A
L
L
K
---------
D
N
D
------
I
Y
F
P
E
ELK
S
A
E
D
Q
L
F
T
M
K
A
Y
L
N
AN
R
I
S
V
L
-
S
D
------
K
A
Y
Y
Y
A
T
K
R
E
G
E
-
H
M
S
S
A
-
Y
V
S
P
E
-
D
F
-
Y
E
V
M
R
L
I
A
V
E
I
-----
L
------------------------
N
A
D
L
-
E
E
------------
A
H
K
D
Q
I
L
A
E
F
L
N
R
H
F
S
F
S
R
--------
T
N
G
F
S
L
K
V
K
L
E
E
Q
P
Q
W
I
N
----------------
A
L
G
D
F
I
Q
A
V
------------
P
E
R
V
D
A
L
V
M
S
K
-
L
R
P
L
L
--
H
Y
A
R
A
KD
I
D
-------
N
Y
R
T
----
V
E
E
S
Y
------------------------
R
--------------------------------
Q
-
G
Q
Y
Y
R
F
D
I
V
D
G
K
L
N
----
I
-----
Q
F
N
E
G
-
E
P
Y
F
E
G
I
D
---
13
PsiBlast_PDB
49.55
25%
-243
- C4 -
-
5KHN
-
?
B:
[715-806]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
I
S
A
F
L
-
H
A
A
L
W
S
I
I
-----
S
I
T
I
L
-
L
W
I
T
L
-
R
R
-
F
G
D
V
L
R
T
L
V
P
L
-----
L
-
V
S
G
-----
I
V
T
L
E
M
C
V
V
L
G
-------------------------
M
S
L
N
F
A
N
I
I
A
L
P
L
M
L
G
V
--------
G
V
A
F
K
V
Y
F
V
M
A
W
R
A
G
Q
T
G
----------------
L
L
H
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
49.14
18%
-127
- C2 -
-
4QFR
3
AAKG1_RAT
C:
[28-322]
---------------------------
Y
T
T
F
M
K
S
H
----------
R
C
Y
D
L
I
P
------------
T
S
S
K
L
V
V
-----
F
D
T
S
L
Q
V
K
K
A
F
F
A
L
V
T
N
G
---
V
-------
R
A
A
P
L
W
D
S
--
K
----
K
Q
S
F
V
G
M
L
T
-
I
T
D
F
I
N
I
-----
L
--
H
R
Y
Y
K
S
A
L
V
Q
----
I
Y
E
L
E
E
H
K
-----
I
E
T
W
R
E
-
V
Y
L
Q
D
S
F
K
---------
P
L
--
V
C
I
S
P
N
A
S
L
F
D
A
V
----------------
S
S
----
L
----
I
R
N
-------------------------
K
I
H
R
L
P
V
I
D
P
-----------------------------------
E
---
S
G
N
T
L
Y
I
L
T
---
H
----
K
R
I
L
-
K
F
L
K
L
F
I
-
T
S
---
L
E
E
L
Q
I
G
-
T
Y
A
N
I
A
M
V
R
T
T
-
T
P
-
V
Y
V
A
L
G
I
F
V
Q
H
RVS
A
L
P
-
V
V
D
-----
E
K
G
R
V
V
D
I
Y
S
K
F
D
V
I
N
L
A
A
-
E
K
------------
T
Y
N
N
--------
L
D
V
S
V
T
K
--------
A
L
Q
H
R
V
L
-
K
C
Y
L
H
E
T
L
E
A
----------------
I
I
N
R
L
V
E
A
E
V
H
-
R
L
-
V
V
V
D
E
H
D
V
V
K
G
I
V
S
L
S
D
-
I
L
Q
A
L
--
V
--------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
47.48
25%
-231
- C4 -
-
5KHS
-
?
B:
[715-806]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
I
S
A
F
L
-
H
A
A
L
W
S
I
I
-----
S
I
T
I
L
-
L
W
I
T
L
-
R
R
-
F
G
D
V
L
R
T
L
V
P
L
-----
L
-
V
S
G
-----
I
V
T
L
E
M
C
V
V
L
G
-------------------------
M
S
L
N
F
A
N
I
I
A
L
P
L
M
L
G
V
--------
G
V
A
F
K
V
Y
F
V
M
A
W
R
A
G
Q
T
G
----------------
L
L
H
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
47.10
12%
-209
- C4 -
-
5NJ3
1
?
A:
[447-661]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
F
S
S
-
V
S
A
V
E
L
F
V
V
E
K
K
-
L
F
I
H
E
-
Y
I
S
G
Y
-
Y
R
V
S
S
Y
F
L
G
K
L
L
S
D
-----
L
L
P
M
R
-----
M
L
P
S
I
I
F
T
C
I
V
Y
F
M
L
G
L
K
P
K
A
D
------------
A
F
F
V
M
M
F
T
L
M
M
V
A
Y
S
A
S
S
M
--------
A
L
A
I
A
A
G
Q
S
V
V
S
V
A
T
L
L
M
-----------------
T
I
C
F
V
F
M
M
I
F
-
S
G
-
L
L
V
N
L
T
T
I
A
S
W
L
S
W
L
Q
Y
-
F
S
I
P
R
--
Y
G
F
T
A
--
L
Q
-------
H
N
E
F
----
L
G
Q
N
F
------------------------
C
PGLNATGNNPCNYATCT
G
E
E
Y
L
V
K
Q
GIDLS
P
W
G
-
L
W
K
N
H
V
A
L
A
C
M
I
V
I
----
F
-----
L
T
I
A
Y
-
L
K
L
L
F
L
K
----
16
HHSearch
46.94
12%
-209
- C4 -
-
5NJG
1
?
B:
[447-661]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
F
S
S
-
V
S
A
V
E
L
F
V
V
E
K
K
-
L
F
I
H
E
-
Y
I
S
G
Y
-
Y
R
V
S
S
Y
F
L
G
K
L
L
S
D
-----
L
L
P
M
R
-----
M
L
P
S
I
I
F
T
C
I
V
Y
F
M
L
G
L
K
P
K
A
D
------------
A
F
F
V
M
M
F
T
L
M
M
V
A
Y
S
A
S
S
M
--------
A
L
A
I
A
A
G
Q
S
V
V
S
V
A
T
L
L
M
-----------------
T
I
C
F
V
F
M
M
I
F
-
S
G
-
L
L
V
N
L
T
T
I
A
S
W
L
S
W
L
Q
Y
-
F
S
I
P
R
--
Y
G
F
T
A
--
L
Q
-------
H
N
E
F
----
L
G
Q
N
F
------------------------
C
PGLNATGNNPCNYATCTGEEYLVKQGIDLSPW
G
-
L
W
K
N
H
V
A
L
A
C
M
I
V
I
----
F
-----
L
T
I
A
Y
-
L
K
L
L
F
L
K
----
20
HHSearch
46.28
13%
-170
- C4 -
-
5DO7
-
ABCG5_HUMAN
C:
[438-646]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
N
L
F
P
V
L
R
A
V
-
S
D
Q
E
S
-
Q
D
G
L
Y
-
Q
K
-
W
Q
M
M
L
A
Y
A
L
H
V
-----
L
-
P
F
S
-----
V
V
A
T
M
I
F
S
S
V
C
Y
W
T
L
G
L
H
P
E
V
A
------------
R
F
G
Y
F
S
A
A
L
L
A
P
H
L
I
G
E
F
L
--------
T
L
V
L
L
G
I
V
Q
N
P
N
I
V
N
S
V
V
-----------------
A
L
L
S
I
A
G
V
L
V
G
S
G
-
F
L
R
N
I
Q
E
M
P
I
P
F
K
I
I
S
Y
-
F
T
F
Q
K
--
Y
C
S
E
I
--
L
V
-------
V
N
E
F
----
Y
G
L
N
F
------------------------
T
CGSMCAFTQ
G
I
Q
F
I
E
K
TCPGATS---------
R
-
F
T
M
N
F
L
I
L
Y
S
F
I
P
A
----
L
-----
V
I
L
G
I
-
V
V
F
K
I
R
D
----
40
Fugue
46.08
17%
-81
- C3 -
-
3WDO
-
?
A:
[3-455]
----------------DYKMT
P
G
E
R
R
A
T
W
G
L
G
T
V
F
----------
S
L
R
M
L
G
M
------------
F
M
V
L
P
V
L
T
T
Y
G
M
A
L
Q
G
A
S
E
A
L
I
G
I
A
I
G
I
Y
G
---
L
T
Q
A
V
F
Q
I
P
F
G
L
L
S
D
R
IG
R
K
P
L
I
V
G
G
L
A
V
F
A
A
-
G
S
V
I
A
A
L
-----
S
DS
I
W
G
I
I
L
G
R
A
L
----
Q
G
S
G
A
I
A
A
A
----
V
M
A
L
L
S
-
D
L
T
R
E
Q
N
R
T
-
K
-
A
--
M
A
F
I
--
G
V
S
F
G
I
T
F
A
I
A
M
V
----------------
L
G
----
P
----
I
I
T
H
K
---
L
G
L
H
---
A
-----------
L
F
W
M
I
A
I
L
A
T
T
G
I
A
L
T
I
W
V
VPNS
S
T
H
V
L
N
R
E
SG
M
V
K
------
G
S
F
S
K
---
V
L
A
E
P
R
L
L
K
L
N
F
G
----
I
M
C
L
-
H
M
L
L
M
S
T
-
F
V
A
L
P
G
Q
L
A
D
A
G
F
P
A
A
E
H
-
W
K
V
Y
L
-
A
T
-
M
L
I
A
F
G
S
V
V
P
F
-----
I
-
I
Y
A
E
VKRK
M
K
Q
V
F
V
F
C
V
G
L
I
V
V
A
E
I
V
L
-
W
N
AQTQ
F
W
Q
L
V
V
G
V
Q
L
F
F
V
A
F
N
L
M
E
A
L
L
P
S
L
I
S
K
E
SPAGY
K
G
T
A
M
G
V
Y
S
T
S
Q
F
L
G
V
A
I
G
G
S
L
G
G
W
I
D
G
M
FD
G
Q
G
V
F
L
A
G
A
M
L
A
A
V
W
-
L
A
-
V
A
S
T
M
K
E
P
P
Y
V
S
S
L
R
I
E
-
I
P
A
D
I
--
A
A
N
E
A
--
L
K
-------
V
R
L
L
----
E
T
E
G
V
------------------------
K
--------------------------------
E
-
V
L
I
A
E
E
E
H
S
A
Y
V
K
I
----
D
-----
S
K
V
T
N
R
F
E
V
E
Q
A
I
R
QAL
21
HHSearch
45.23
13%
-162
- C4 -
-
5DO7
-
ABCG5_HUMAN
A:
[438-646]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
N
L
F
P
V
L
R
A
V
-
S
D
Q
E
S
-
Q
D
G
L
Y
-
Q
K
-
W
Q
M
M
L
A
Y
A
L
H
V
-----
L
-
P
F
S
-----
V
V
A
T
M
I
F
S
S
V
C
Y
W
T
L
G
L
H
P
E
V
A
------------
R
F
G
Y
F
S
A
A
L
L
A
P
H
L
I
G
E
F
L
--------
T
L
V
L
L
G
I
V
Q
N
P
N
I
V
N
S
V
V
-----------------
A
L
L
S
I
A
G
V
L
V
G
S
G
-
F
L
R
N
I
Q
E
M
P
I
P
F
K
I
I
S
Y
-
F
T
F
Q
K
--
Y
C
S
E
I
--
L
V
-------
V
N
E
F
----
Y
G
L
N
F
------------------------
T
CAFTQ
G
I
Q
F
I
E
K
TCPGATS-------------
R
-
F
T
M
N
F
L
I
L
Y
S
F
I
P
A
----
L
-----
V
I
L
G
I
-
V
V
F
K
I
R
D
----
41
Fugue
43.55
15%
-23
- C5 -
-
1DIK
-
?
?:
[510-874]
---------------------
I
E
T
Q
E
A
S
V
S
G
S
F
E
R
----------
I
M
V
W
A
D
K
F
RT
L
K
V
R
T
NADT
P
E
D
T
L
N
A
V
K
L
G
A
E
G
I
G
L
C
R
T
E
H
M
F
F
---------
E
A
D
R
I
M
K
I
R
K
M
I
L
S
D
--
S
V
E
A
R
E
E
A
L
N
E
L
I
P
-
F
Q
K
G
D
F
K
-----
A
M
-
Y
K
A
L
E
G
R
P
M
T
----
V
R
Y
--
L
D
P
-----
P
L
H
E
----
F
V
P
H
T
E
E
E
-
Q
-
A
--
E
L
A
K
--
N
M
G
L
T
L
A
E
V
K
A
K
V
----------------
D
E
----
L
----
H
E
F
N
P
---
M
M
G
H
R
G
C
R
-----------
L
A
V
T
Y
P
E
I
A
K
M
Q
T
R
A
V
M
----------------
E
A
A
------
I
E
V
K
E
---
E
T
G
I
D
--
I
V
P
E
I
M
----
I
P
--------------
L
V
G
E
K
K
E
L
K
-
F
V
K
D
V
-
V
V
E
V
A
-
E
Q
-
V
K
K
E
K
G
S
D
M
Q
Y
-----
H
-
I
G
T
-----
M
I
E
I
P
R
A
A
L
T
A
D
A
I
A
E
E
A
----------------
E
F
F
S
F
G
----
T
N
D
L
T
Q
M
T
F
--------
G
F
S
---------
R
D
D
A
G
K
----------------
F
L
D
S
Y
Y
K
A
K
I
Y
-
E
S
-
D
P
F
A
R
L
D
Q
T
G
V
G
Q
L
V
E
M
-
A
V
K
K
G
--
R
Q
T
R
P
--
G
L
-------
K
C
G
I
C
G
EH
G
G
D
P
S
------------------------
S
--------------------------------
V
E
F
C
H
K
V
G
--
L
N
Y
V
S
C
S
PFR
V
-----
P
I
A
R
L
-
A
A
A
Q
A
A
L
N
N
K-
33
Fugue
41.85
12%
-36
- C4 -
-
4B28
-
DDDP_ROSDO
A:
[32-468]
RKIDPSRGATLGDGSPNDMNR
V
E
I
G
P
T
Q
L
A
F
A
E
W
H
T
A
R
L
D
L
P
D
L
A
A
M
R
R
F
R
H
------------
R
R
L
T
D
H
V
V
A
R
G
Y
A
G
L
L
M
F
D
P
L
N
I
R
Y
A
T
D
S
T
NM
Q
L
W
N
T
H
N
P
F
R
A
T
L
L
C
A
D
--
G
Y
----
M
V
M
W
D
Y
K
N
-
S
P
F
L
S
E
F
NPLVR
E
--
Q
R
A
G
A
D
L
F
Y
F
----
D
R
G
D
K
V
D
V
-----
A
A
D
V
F
A
-
N
E
V
R
I
L
L
R
D
-
H
-
A
PG
L
R
R
L
--
A
V
D
K
V
M
L
H
G
L
R
A
L
----------------
Q
A
Q
GFE
I
----
M
D
G
E
E
---
V
T
E
K
---
A
R
SVKG
P
D
E
I
R
A
M
R
C
A
S
H
A
C
E
V
A
V
R
K
M
E
D
----------------
F
A
R
------
S
K
V
G
D
---
G
V
T
C
E
N
D
I
W
A
I
L
H
----
S
E
N
V
-
R
R
G
G
E
W
I
E
T
R
L
L
A
S
G
P
R
S
N
P
-
W
F
Q
E
C
-
G
P
R
V
C
-
Q
R
-
N
E
I
I
S
F
D
T
D
---------
L
V
G
-----
A
Y
G
I
C
T
D
I
S
R
S
W
W
I
G
D
Q
K
P
-
R
A
------------
D
M
I
Y
A
M
Q
H
G
V
E
H
I
R
T
N
M
E
M
LKP-----
G
V
M
I
P
E
L
S
A
N
T
H
V
L
D
A
K
F
----------------
Q
K
Q
K
Y
G
C
L
M
H
G
-
V
G
-
L
C
D
E
W
P
L
V
A
Y
P
D
H
A
V
A
G
-
A
Y
D
Y
P
L
E
P
G
M
T
L
--
C
V
-------
E
A
L
I
----
S
E
E
G
G
------------------------
D
--------------------------------
F
------
S
I
K
L
E
D
Q
V
L
----
I
T
ED
G
Y
E
N
L
T
K
-
Y
P
F
D
P
A
L
M
G--
18
HHSearch
38.64
13%
-171
- C4 -
-
5DO7
-
ABCG8_HUMAN
B:
[472-667]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
C
Y
S
E
R
A
-
M
L
Y
Y
E
-
L
E
D
G
L
Y
T
T
-
G
P
Y
F
F
A
K
I
L
G
E
-----
L
-
P
E
H
-----
C
A
Y
I
I
I
Y
G
M
P
T
Y
W
L
A
N
L
R
P
G
L
Q
------------
P
F
L
L
H
F
L
L
V
W
L
V
V
F
C
C
R
I
M
--------
A
L
A
A
A
A
L
L
P
T
F
H
M
A
S
F
F
S
-----------------
N
A
L
Y
N
S
F
Y
L
A
-
G
G
-
F
M
I
N
L
S
S
L
W
T
V
P
A
W
I
S
K
-
V
S
F
L
R
--
W
C
F
E
G
--
L
M
-------
K
I
Q
F
----
S
R
R
T
Y
K
M
P
L
G
NLTIAVSGD
K
I
L
S
V
M
ELDS
Y
--------------------------------
P
-
L
Y
A
I
Y
L
I
V
I
G
L
S
G
G
----
F
-----
M
V
L
Y
Y
-
V
S
L
R
F
I
-----
19
HHSearch
38.30
13%
-170
- C4 -
-
5DO7
-
ABCG8_HUMAN
D:
[472-667]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
C
Y
S
E
R
A
-
M
L
Y
Y
E
-
L
E
D
G
L
Y
T
T
-
G
P
Y
F
F
A
K
I
L
G
E
-----
L
-
P
E
H
-----
C
A
Y
I
I
I
Y
G
M
P
T
Y
W
L
A
N
L
R
P
G
L
Q
------------
P
F
L
L
H
F
L
L
V
W
L
V
V
F
C
C
R
I
M
--------
A
L
A
A
A
A
L
L
P
T
F
H
M
A
S
F
F
S
-----------------
N
A
L
Y
N
S
F
Y
L
A
-
G
G
-
F
M
I
N
L
S
S
L
W
T
V
P
A
W
I
S
K
-
V
S
F
L
R
--
W
C
F
E
G
--
L
M
-------
K
I
Q
F
----
S
R
R
T
Y
K
M
P
L
GNL
T
I
A
V
S
GD
K
I
L
S
V
M
ELDS
Y
--------------------------------
P
-
L
Y
A
I
Y
L
I
V
I
G
L
S
G
G
----
F
-----
M
V
L
Y
Y
-
V
S
L
R
F
I
-----
15
HHSearch
38.24
9%
-118
- C4 -
-
5XJY
2
?
A:
[531-1115]
---------------------------------------------------------------------------------------------------------------------------------------
L
E
-----
P
--
I
A
T
E
V
W
L
I
N
K
S
M
E
L
L
D
E
R
K
F
W
A
-----
G
I
V
F
T
G
-
I
T
P
G
S
I
E
L
P
-
H
H
V
--
K
Y
K
I
--
R
M
D
I
D
N
V
E
R
T
N
K
I
KDGYWDPGPRADPFED
M
R
----
Y
----
V
W
G
G
F
A
Y
L
Q
D
V
V
---
E
-----------
Q
A
I
I
R
V
L
-
T
G
T
E
K
K
T
G
V
----------------
Y
M
Q
Q
MPYPC
Y
V
D
D
I
---
F
L
R
V
M
S
R
S
M
P
L
F
M
----
T
L
A
W
-
I
Y
S
-
V
A
V
-
I
I
K
G
I
V
Y
E
K
E
A
R
-
L
K
E
T
M
-
R
I
M
G
L
-
D
N
-
S
I
L
W
F
S
W
F
I
S
S
-------
L
I
P
-----
L
L
V
S
A
G
L
L
V
V
I
L
K
L
G
N
L
L
P
-
Y
S
------------
D
P
S
V
V
F
V
F
L
S
V
F
A
V
V
T
I
L
Q
--------
C
F
L
I
S
T
L
F
S
R
A
N
L
A
A
A
C
G
-----------------
G
I
I
Y
F
T
L
Y
L
P
-
Y
V
L
C
V
A
W
Q
D
Y
V
G
F
T
L
K
I
F
A
S
L
L
S
P
V
A
--
F
G
F
G
C
--
E
Y
F
A
L
F
EEQ-------------------------------------------------------------------------
G
F
N
L
T
T
S
V
S
M
M
L
F
----
D
-----
T
F
L
Y
G
-
V
M
T
W
Y
I
-----
22
HHSearch
37.59
19%
-38
- C4 -
-
3CNI
-
?
A:
[11-105]
--------------------------------------------------------------------------------------------------------
Q
K
V
A
I
V
R
E
D
--
T
G
T
I
A
E
L
A
E
K
A
L
G
---
N
M
V
D
I
V
Y----
A
--
G
S
D
L
K
E
A
E
E
A
----
V
K
K
E
K
A
P
A
-----
I
I
V
I
P
K
-
G
F
S
Q
S
L
E
S
G
-
E
K
A
--
R
L
E
I
V
W
Y
L
R
G
T
G
L
-
S
E
A
V
S
----------------
T
G
----
T
----
I
S
S
L
I
---
E
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
36.58
12%
-105
* C6 *
-
5AOO
-
?
B:
[13-370]
--------------------------------------------------------------------
N
V
T
T
D
V
G
A
----------------
N
G
---
W
A
P
T
V
S
T
G
L
G
D
G
P
V
S
A
--
S
A
D
S
L
P
G
R
S
G
G
A
S
S
-
E
K
T
K
V
G
S
-----
R
--
F
S
K
W
W
E
P
A
P
S
----
S
---
T
A
N
P
-----
Q
P
S
L
I
A
-
L
N
P
S
A
T
Q
S
G
-
N
-
A
--
S
I
L
T
--------
G
S
T
A
P
S
L
----------------
L
A
----
Y
----
P
T
A
T
P
---
V
P
L
P
---
N
-----------
P
D
E
P
S
Q
P
G
P
S
G
D
R
T
W
L
L
----------------
D
T
V
------
T
W
S
Q
E
---
F
T
R
G
W
N
I
A
G
S
N
G
M
---------
Q
W
T
G
L
E
S
-
L
I
F
P
V
S
T
D
T
N
W
T
-
S
T
S
S
----
P
T
A
-
Y
P
-
L
P
F
S
F
V
R
A
Y
P
D
-----
S
-
S
W
A
-----
A
M
Y
N
T
H
S
M
W
N
C
G
W
R
V
Q
V
T
V
-
N
G
------------
S
Q
F
H
A
G
A
L
I
L
Y
M
V
P
E
A
T
T
H
--------
A
I
Q
T
A
R
D
N
A
G
F
V
F
P
Y
V
I
L
----------------
N
L
Y
E
S
N
T
A
T
I
E
-
V
P
-
Y
I
S
P
T
P
N
T
S
S
G
L
H
------
A
P
W
T
--
F
Y
L
Q
V
--
L
S
-------
P
L
N
P
----
P
P
S
L
P
------------------------
T
---------------------------------------
S
L
S
C
S
I
Y
V
T
----
P
-----
V
D
S
S
F
-
H
G
L
R
Y
L
A
P
Q--
32
Fugue
35.13
15%
-22
- C4 -
-
3CNI
-
?
A:
[11-155]
--------------------------------------------------------------------------------------------------------
Q
K
V
A
I
V
R
E
D
--
T
G
T
I
A
E
L
A
E
K
A
L
G
N
M
V
D
I
V
Y
A
---------
G
S
D
L
K
E
A
E
E
A
----
V
K
K
E
K
A
P
A
-----
I
I
V
I
P
K
-
G
F
S
Q
S
L
E
S
G
-
E
K
A
--
R
L
E
I
--
V
W
Y
L
R
G
T
G
L
S
E
A
V
----------------
S
T
----
G
----
T
I
S
S
L
---
I
E
S
L
---
K
-----------
V
Q
L
A
S
F
L
L
N
D
P
K
K
A
Q
L
L
----------------
F
D
P
------
L
E
I
V
Q
---
H
T
Y
L
R
G
S
L
F
K
N
H
S
----
P
E
A
I
M
N
V
F
Y
S
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
35.10
19%
-125
* C4 *
-
5H0N
-
?
B:
[1-31]
----------------------------
M
T
W
E
E
W
D
----------
K
K
I
E
E
Y
T
------------
K
K
I
E
E
L
I
K
K
S
Q
N
Q
Q
I
D
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
31.95
25%
-59
- C4 -
-
3CNI
-
?
A:
[43-109]
---------------------------------------------------------------------------------------------------------------------------------------------------
D
L
K
E
A
E
E
A
----
V
K
K
E
K
A
P
A
-----
I
I
V
I
P
K
-
G
F
S
Q
S
L
E
S
G
E
K
-
A
--
R
L
E
I
--
V
W
Y
L
R
G
T
G
L
S
E
A
V
----------------
S
T
----
G
----
T
I
S
S
L
---
I
E
S
L
---
K
-----------
V
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
29.40
26%
-196
- C4 -
-
5DO7
-
ABCG5_HUMAN
C:
[363-414]
-------------------------------
G
V
F
S
----------
K
L
G
V
L
L
R
------------
R
V
T
R
N
L
V
R
N
K
L
A
V
I
T
R
L
L
Q
N
L
I
M
G
L
F
L
L
F
F
---
V
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------