@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VRQ2: (2017-12-04 )
MIEELLPFYEKQLQEFGQQSREFAQKYPKIAQRLSLNQEQIDDPHIERLIQAFSLIAARIDKKLTDSYDVFTRSLFEVMFPQYLRHFPACSVVSFEDINKIKQLTEPHLVPHHTVLKSRSFKGVQCEFNTTQDVRLLPIHLSGLDFKTTPSAHMHLNQNATLSLKFEIFNNAHACLTDEKLPIYLDAISNFPLQVLDSIFKKGTSFAVKYGQIIVELSKNPFELTGFAEQESLLPLDQHTHHAYRLLMEYFCFPEKFSYLKLDLDFLKRIPQHVSEFELLIHFKLNLNDQAVVRNYSELNIANFKLFTTPVINLFEKYAEPQKIVHKQLEYPLVTDAHHPEFYQVYSILEMNMVREKTNQEESYVPVLPFFAMSHYHNDTARFFYSVNYQKLQSNFVEMGYSIISKNLNPFSTRSDFISTKLLCSNRDLPHEALGQSNNVLNLNDSSLARRAIVLKRPTKPYKFEQGQSEQWRVISHLSLNSLALMKGDAVSLVKELLALYNLPQSKENYLIIESIKKLEFSLTHKLVDGKPFPMFVRGVKAELQIDSSVFRGHSLYIFSQLLSRVFNLKVQINSFVDLVVKDYSSQQELYQCSQNVGGKTLL
Atome Classification :
(20 SA)
-----------------------------------------------------------.........10.--.......20........30..------......40-...----.....50.......------.60....----....70-....---.....80.---.....--..90...-----------.....100....--...-110........120-.--..--.....130-........------------------140-----------------------........150..--.....-160.....--...--170...------...------------------.180......-.190---.......200-----..-----.....-----------..210-...----------......220........----230...--...-.240.......250---....------------...260.......270.....----....280......-.290....--...-----300.----......310...-----------------------....320.......330..-.....--------340.....---..350.....-..360.......370.......380........----390.......---400.----.-.....410....--------.-..420.......430..-----.....440........450-------------------...---.....460....-------...470.......480.......490.......500--.......510..-----.....520----------........530.......540.......550.--...---....560..------.....570--------....-------.....580.......590----.......600.-----------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------------------------------------------------------
M
I
E
E
L
L
P
F
Y
E
K
Q
--
L
Q
E
F
G
Q
Q
S
R
E
F
A
Q
K
Y
P
K
I
A
Q
R
------LSL
N
Q
EQI-D
D
P
----
H
I
E
R
L
I
Q
A
F
S
L
I
A
A
------
R
I
D
K
K
LT----D
S
Y
D
V
--
F
T
R
S
---
L
F
E
V
M
F
P
Q
---
Y
L
R
HF--PACSVV
S
-----------
F
E
D
I
N
K
I
K
Q
LTE--PHL-V
P
-
H
H
T
V
L
KSRSF--K--
G
V
--
Q
C
E
FNTT--
Q
D
V
R
L
L
P
I
------------------
H
L------------------------SGLDFKTTPS
A
H
M
--
H
LNQN-
A
T
-
L
S
L
K
F
--
E
I
F--NNAHAC------LTD------------------EKL
P
I
Y
L
D
A
I-SNF
P
---
L
Q
V
L
D
S
I
F
-------KK-----GT
S
F
A
-----------
V
K
Y
---
G
Q
I
----------
I
V
E
LSKN-P
F
E
L
TGFAE----QESLLP--LDQ-H
T
H
H
A
Y
R
L
L
M
E
YFC---FPEK------------
F
S
Y
L
KL
D
L
D
F
L
K
R
I
--
P
Q
H
V
S
----
E
F
E
L
L
I
H
F
K
LNLN-
D
Q
A
V
V
R
N
Y
--SEL-----NIA
N
----
F
K
L
F
T
T
P
V
I
N
L
F
-----------------------
E
K
YA
E
P
Q
K
I
V
H
K
QLEYPLV-TDAH
H
--------
P
E
F
Y
Q
V
Y
S
---
I
L
E
M
N
M
V
R
EK-TNQEESYVP
V
L
P
F
F
A
M
S
H
YHND
T
-
A
R
F
F
Y
S
V
N
Y
----
Q
K
L
Q
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N
F
V
E
M
---
G
Y
S
I
----
I
-SKNLNPFST
R
S
D
--------
F
-
I
S
T
K
L
L
CSNRDL
P
H
E
A
L-----GQSN
N
V
-
L
NLN
D
S
S
L
A
R
R
--------------------
A
I
V
---LKRPTKPYKFEQ-------GQSE
Q
W
R
V
I
S
HLSL
N
S
L
ALMKG
D
A
V
S
L
V
K
E
L
L
A
L
YN--LPQSKE
N
Y
L
I
I
E
-----
S
I
K
K
L
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F
-----------
S
L
T
HKLVDGKPFP
M
F
V
RG
V
K
A
E
L
Q
IDSSV-FR--G
H
S
---
L
Y
I
F
S
Q
L
L
S
------
R
V
FN
L
K
----------
V
Q
I
N
-------
S
F
V
D
L
V
V
KDYS
S
Q
Q
E
L
Y
Q
----
C
S
Q
NVGGKTLL-----------------------------------------------------------------------
23
Fugue
67.38
17%
15
- C2 -
-
4X0Q
6
DPOLQ_HUMAN
A:
[6-772]
--------------------------------------------------------------------
S
L
S
--
I
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----
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V
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L
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G
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------
Y
Y
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L
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----
P
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-----
L
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L
K
---
D
R
M
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---
C
L
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K
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V
V
I
-----------
Y
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L
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--
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G
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------------------
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------------------------
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--
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L
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--
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R
Y
R
A
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------
V
E
S
------------------
I
L
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M
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Q
L
N
S
L
L
Q
---
K
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N
L
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V
F
-------
R
K
------
V
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M
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-----------
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Q
Y
---
C
L
A
----------
L
L
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L
N
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G
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A
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C
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----
Q
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---
F
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------------
D
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--
P
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----
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-
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G
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A
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---
Q
L
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L
-
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R
L
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V
L
N
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---
A
D
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F
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S
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-
A
A
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W
K
M
I
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D
D
L
R
Q
Q
A
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---
C
Y
G
I
----
I
Y
G
M
G
A
K
S
L
G
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Q
M
G
--------
I
-
K
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N
D
A
A
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Y
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R
-
Y
-----
T
G
I
N
Q
F
-
M
T
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K
N
C
K
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D
--------------------
G
F
V
Q
T
I
L
G
R
R
R
Y
L
P
G
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K
D
-------
N
N
P
Y
R
K
A
H
A
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R
Q
A
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N
--
T
I
V
Q
G
S
A
A
D
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K
--
I
A
T
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N
--
I
Q
K
Q
L
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F
-----------
H
S
T
F
K
-----------
S
H
G
H
R
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G
M
L
Q
S
-
D
C
P
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R
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G
F
F
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Q
L
H
D
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L
-
L
Y
--
E
V
A
EED
V
V
Q
V
A
Q
I
V
K
------
N
E
M
E
S
A
----------
V
K
L
S
-------
V
K
L
K
V
K
V
K
I
G
A
S
W
G
E
L
K
D
----
F
D
V
-------------------------------------------------------------------------------
16
Fugue
61.78
18%
16
- C2 -
-
4X8E
9
EGTB_MYCT3
A:
[8-435]
------------------------------------------------------PH
R
A
E
L
A
R
Q
L
I
D
A
R
N
R
T
--
L
R
L
V
D
F
D
D
A
E
L
R
R
Q
Y
----------------------
D
P
----
L
M
S
P
L
V
W
D
L
A
H
I
G
Q
------
Q
E
E
L
W
L
L
----
R
G
G
D
--------------------------------------------------
P
R
R
P
G
L
L
E
--
P
A
V
-
E
Q
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L
Y
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A
F
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H
P
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A
--
S
--
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L
P
L
L
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--
A
Q
A
R
R
F
C
A
------------------
T
V
------------------------
R
S
A
V
L
D
A
L
D
R
------
L
P
E
D
-
A
D
--
T
F
A
F
--
G
M
V
--
V
-
S
H
E
H
------
Q
H
D
------------------
E
T
M
L
Q
A
L
N
L
R
-
S
G
E
P
---
L
L
G
S
G
T
A
L
-------
P
P
-----
G
R
P
G
V
-----------
A
G
T
---
S
V
L
----------
V
---
P
G
G
-
P
F
V
L
-
G
V
D
L
----
A
D
E
P
Y
A
--
L
D
N
-
E
-
R
P
A
H
V
V
D
V
P
A
F
R
---
I
G
--------------------------
R
V
--
P
V
T
N
A
----
E
W
R
A
F
I
D
--------
D
G
G
Y
R
Q
R
--
R
W
W
-----
S
----------------------------------------------------
D
A
G
W
A
Y
R
C
E
-
A
G
L
T
A
--------
P
Q
F
W
N
P
D
G
---
T
R
T
R
F
G
H
V
E
D
-
I
P
P
D
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P
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V
Q
H
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Y
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A
E
A
Y
A
A
W
A
G
A
R
L
P
T
E
I
E
W
----
E
K
A
C
A
---------------------
W
D
P
A
T
G
R
R
--------------------
R
R
Y
P
W
G
D
A
-----
A
P
T
A
A
L
-
A
N
L
G
G
D
A
L
-------------------------------
R
P
A
P
V
G
A
Y
P
A
-------
G
A
S
A
C
----------
G
A
E
Q
M
L
G
D
V
W
E
W
T
S
S
P
L
R
P
W
P
G
F
T
P
M
I
Y
Q
R
Y
-----------------------------
S
Q
P
F
F
E
G
A
G
S
G
------------
D
Y
R
V
-
L
R
--
G
G
S
---
W
A
V
A
A
D
I
L
R
------
P
S
F
R
-----------------------------
N
W
D
H
P
I
R
R
Q
I
F
A
----
G
V
R
L
A
W
D
V
D
-------------------------------------------------------------------------
24
Fugue
60.56
18%
22
- C1 -
-
5DZT
1
?
A:
[4-992]
NLINVLS
I
N
E
R
C
F
L
L
K
Q
S
GNEKYDI
K
N
L
Q
A
W
K
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RKSVLK
Q
D
D
L
D
Y
L
I
K
YKYES
L
D
N
F
G
L
G
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T
P
I
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N
F
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D
K
E
--
V
A
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Q
Y
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K
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Q
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W
Y
I
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F
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S
I
L
D
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------
Y
N
D
S
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Q
L
-
L
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DASY
P
F
R
Y
F
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Q
Y
A
R
L
F
L
L
------
D
L
N
S
E
L
N
----
I
C
T
K
E
--
F
I
I
N
---
L
L
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I
L
T
Q
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---
L
I
H
L
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--
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L
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I
Y
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Q
N
------------------
C
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NIQSSELNSISESQGDSHSRG
K
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T
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G
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NVTDLHYENI
I
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---
G
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----------
P
V
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I
D
N
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T
F
F
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----
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L
M
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----
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S
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K
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L
A
Y
I
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N
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Q
N
L
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R
N
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IR
P
T
Q
-----
R
Y
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----
M
L
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F
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Y
H
-
P
N
C
F
-----------------------
S
N
A
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K
V
L
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W
A
Y
P
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N
K
K
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V
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--------
Y
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N
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T
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S
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----
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---
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I
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F
Y
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---
L
K
Y
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Y
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-------
V
I
E
C
I
K
N
S
I
Y
T
I
P
S
E
D
I
L
S
A
F
F
G
K
G
S
L
I
Y
P
L
L
V
D
Y
R
--
L
N
N
D
I
N
S
L
N
V
A
V
-----
E
I
A
D
M
D
W
IHGH
N
S
I
I
K
V
L
L
L
L
S
E
I
T
E
D
E
K
Y
R
K
F
S
L
E
I
F
E
K
L
S
E
E
P
Y
F
N
F
R
GF
G
H
G
---
I
Y
S
Y
V
H
L
L
S
K
F
NRI
D
K
A
N
S
L
L
----------
H
K
I
K
NNSWCKG
T
V
G
E
L
L
A
T
D
I
N
K
T
I
E
Y
K
N
KDCL
C
H
G
N
A
G
T
L
E
G
L
I
Q
L
A
K
K
DPETY
Q
Y
K
K
N
K
L
I
S
Y
M
L
K
Y
F
E
K
N
NTLKVAGSEYLESLGFFVG
I
S
G
V
G
Y
E
L
L
R
N
L
DSEIPNALLFE
4
PsiBlast_PDB
51.84
35%
-118
- C3 -
-
3AOI
-
GFH1_THET8
X:
[12-63]
-------------------------------------------------------------------
Y
E
R
L
--
M
Q
Q
L
-
E
R
E
R
E
R
L
Q
E
A
T
K
I
L
Q
E
------
L
M
E
S
S
D
D
Y
-
D
D
S
----
G
L
E
A
A
K
Q
E
K
A
R
I
E
A
------
R
I
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
46.73
12%
28
- C2 -
-
4AM6
-
ARP8_YEAST
A:
[33-655]
------------------------------------EIDLNDPTA
T
I
V
I
H
P
G
SN
S
I
K
I
G
F
P
K
D
D
H
P
V
V
V
P
N
--
C
V
A
V
P
K
K
W
L
D
L
E
N
S
E
H
V
E
N
V
C
------
L
Q
R
E
Q
S
E
E
-
F
N
N
----
I
K
S
E
M
E
K
N
F
R
E
R
M
R
------
Y
Y
K
R
K
V
P
----
G
N
A
H
E
--
Q
V
V
S
---
F
N
E
N
S
K
P
E
---
I
I
S
E
K
--
N
D
P
S
P
I
E
-----------
W
I
F
D
D
S
K
L
Y
Y
G
S
--
D
A
L
R
C
V
-
D
E
K
F
V
I
R
K
P
F
--
R
--
G
G
--
S
F
N
V
K
S
P
YY
K
S
L
A
E
L
I
S
------------------
D
V
------------------------
T
K
L
L
E
H
A
L
N
S
E
T
L
--
N
V
K
P
T
-
K
F
-
N
Q
Y
K
V
--
V
L
V
I
P
D
I
F
K
K
S
------
H
V
E
------------------
T
F
I
R
V
L
L
T
E
L
-
Q
F
Q
A
---
V
A
I
I
Q
E
S
L
-------
A
T
-----
C
Y
G
A
G
-----------
I
S
T
---
S
T
C
----------
V
V
N
I
G
A
A
-
E
T
R
I
A
C
V
D
E
GTVL
E
H
S
A
I
T
--
L
D
Y
-
G
G
D
D
I
T
R
L
F
A
L
F
L
L
Q
S
D
F
P
L
Q
DWKIDS
K
H
G
W
L
L
A
E
R
L
K
K
N
F
T
T
F
Q
D
A
--
D
V
A
V
Q
----
L
Y
N
F
M
N
R
S
P
N
Q
P
T
-
E
K
Y
E
F
K
L
F
--
D
E
V
-----
M
L
A
P
----
L
A
L
F
F
P
Q
I
F
K
L
I
-----------------------
R
T
S
S
H
K
N
S
S
L
E
F
Q
L
--
P
E
S
-
R
D
L
F
T
--------
N
E
L
N
D
W
N
S
---
L
S
Q
F
E
S
K
E
G
N
L
Y
C
D
L
N
D
D
L
K
I
L
N
R
I
L
D
A
H
N
I
I
D
Q
-
L
Q
D
K
P
E
N
Y
G
----
N
T
L
K
E
N
F
A
P
L
---
E
K
A
I
----
V
-
Q
S
I
A
N
A
S
I
T
A
D
V
--------
T
-
R
M
N
S
F
Y
S
N
-----
I
L
I
V
-----
G
G
S
S
K
I
-
P
A
L
D
F
I
L
T
D
R
I
--------------------
N
I
W
---
R
P
S
L
L
S
S
--------------
A
S
F
P
Q
F
Y
K
K
L
T
K
E
I
K
D
L
E
G
H
Y
V
N
A
P
D
K
T
E
D
E
N
K
Q
--
I
L
Q
A
Q
I
K
E
K
I
V
E
-----
E
L
E
E
Q
H
Q
-----------
N
I
E
H
Q
N
G
N
E
H
I
F
P
V
S
I
I
P
P
P
R
D
M
N
P
A
L
I
I
-
W
K
--
G
A
S
---
V
L
A
Q
I
K
L
V
E
------
E
L
F
---------------------------------
I
T
N
S
D
W
D
V
H
----
G
S
R
I
L
Q
Y
K
C
I
F
TY---------------------------------------------------------------------
3
PsiBlast_PDB
46.70
35%
-89
- C3 -
-
3AOH
-
GFH1_THET8
X:
[12-63]
-------------------------------------------------------------------
Y
E
R
L
--
M
Q
Q
L
-
E
R
E
R
E
R
L
Q
E
A
T
K
I
L
Q
E
------
L
M
E
S
S
D
D
Y
-
D
D
S
----
G
L
E
A
A
K
Q
E
K
A
R
I
E
A
------
R
I
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
46.38
35%
-65
- C3 -
-
2F23
-
GFH1_THET2
A:
[12-63]
-------------------------------------------------------------------
Y
E
R
L
--
M
Q
Q
L
-
E
R
E
R
E
R
L
Q
E
A
T
K
I
L
Q
E
------
L
M
E
S
S
D
D
Y
-
D
D
S
----
G
L
E
A
A
K
Q
E
K
A
R
I
E
A
------
R
I
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
45.86
32%
-60
- C3 -
-
2ETN
-
GFH1_THEAQ
A:
[12-73]
-------------------------------------------------------------------
Y
E
R
L
--
M
K
Q
L
-
E
Q
E
R
E
R
L
Q
E
A
T
K
I
L
Q
E
------
L
M
E
S
S
D
D
Y
-
D
D
S
----
G
L
E
A
A
K
Q
E
K
A
R
I
E
A
------
R
I
D
S
--------
L
E
D
V
--
L
S
R
A
---
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
45.45
35%
-71
- C3 -
-
2EUL
-
GFH1_THET8
A:
[12-63]
-------------------------------------------------------------------
Y
E
R
L
--
M
Q
Q
L
-
E
R
E
R
E
R
L
Q
E
A
T
K
I
L
Q
E
------
L
M
E
S
S
D
D
Y
-
D
D
S
----
G
L
E
A
A
K
Q
E
K
A
R
I
E
A
------
R
I
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
41.03
15%
4
- C2 -
-
4HNE
1
P4K2A_HUMAN
A:
[2-384]
-----------------------------------------------------------------
P
L
G
S
P
E
--
F
A
A
Q
A
Q
A
L
A
A
Q
A
A
A
A
A
H
A
A
Q
A
------
H
R
E
R
N
E
F
P
-
E
D
P
----
E
F
E
A
V
V
R
Q
A
E
L
A
I
E
R
CI
F
P
E
R
I
Y
Q
G
S
S
----
G
S
Y
F
V
K
D
P
Q
G
R
---
I
I
A
V
F
K
P
K
---
N
E
E
P
Y
--
G
H
L
N
P
--------------
K
W
T
K
W
L
Q
K
F
G
R
--
D
C
L
-
V
L
-
N
Q
G
Y
L
S
E
A
G
A
--
S
--
L
V
D
Q
K
L
E
L
N
I
V
--
P
R
T
K
V
V
Y
L
A
S
ETF-------------
N
Y
------------------------
S
A
I
D
R
V
K
S
R
G
K
R
L
--
A
L
R
F
N
-
R
I
G
L
P
P
K
V
--
G
S
F
--
Q
L
F
V
E
G
------
Y
K
D
------------------
A
D
Y
W
L
R
R
F
E
A
-
E
P
L
P
---
E
N
T
N
R
Q
L
L
-------
L
Q
-----
F
E
R
L
V
-----------
V
L
D
---
Y
I
I
RNTDRGNDN
W
L
I
K
Y
D
C
P
-
P
V
I
K
V
A
A
I
D
----
N
G
L
A
F
P
--
L
K
H
P
D
S
W
R
A
Y
P
F
Y
W
A
W
L
P
---
Q
A
K
V
------------
P
F
S
Q
E
I
K
D
L
I
L
P
K
I
SD
P
N
F
V
K
----
D
L
E
E
D
L
Y
E
L
F
K
-
K
-
D
P
G
F
D
R
G
Q
--
F
H
K
-----
Q
I
A
V
----
M
R
G
Q
I
L
N
L
T
Q
A
L
-----------------------
K
D
N
K
S
P
L
H
L
V
Q
M
P
---
P
V
I
-
V
E
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
39.23
21%
-135
- C3 -
-
1TU3
-
RABE1_HUMAN
F:
[21-66]
--------------------------------------------------------------------
A
Q
R
--
L
Q
T
E
L
D
V
S
E
Q
V
Q
R
D
F
V
K
L
S
Q
T
------
L
Q
V
Q
L
E
R
I
-
R
Q
A
----
D
S
L
E
R
I
R
A
I
L
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
38.28
14%
-
- C- -
-
3WAI
-
MALE_ECOLI
A:
[-1-868]
----------------------------------------
M
K
I
E
EG
K
L
V
I
W
I
N
GDKG
Y
N
G
L
A
E
V
G
K
K
F
E
K
D
TG
I
K
V
T
V
E
H
P
D
K
L
E
E
K
F
P
Q
V
A
A
T
GDGPD
I
I
F
W
A
H
D
R
F
-
G
G
Y
----
A
Q
S
G
L
L
A
E
I
T
P
D
K
A
------
F
Q
D
K
L
Y
P
----
F
T
W
D
A
--
V
R
Y
N
---
G
K
L
I
A
Y
P
I
---
A
V
E
-----
A
L
S
L
I
Y
-----------
N
K
D
L
L
P
N
P
P
K
T
W
--
E
E
I
-
P
A
-
L
D
K
E
L
K
A
K
G
K
--
S
--
A
L
--
M
--
F
N
L
Q
--
E
P
Y
F
T
W
P
L
I
A
ADGGYAFKDVGVDN
A
G
A
K
------------------------
A
G
L
T
F
L
V
D
L
I
K
N
K
--
H
M
N
A
D
-
T
D
-
Y
S
I
A
E
--
A
A
F
--
N
K
G
E
T
A
------
M
T
I
N
G
PWA
W
S
N
I
D
T
S
KVN
Y
G
V
T
V
L
P
T
F
K
G
Q
P
-
S
K
P
F
---
V
G
V
L
S
A
G
I
N
AASPN
K
E
L
-----
A
K
E
F
L
-----------
E
N
Y
LLT
D
E
G
----------
L
E
A
V
N
K
D
K
P
L
G
A
V
A
L
K
S
----
Y
E
E
E
L
A
--
K
D
P
-
R
I
A
A
T
M
E
N
A
Q
K
G
E
I
---
M
P
N
I
------------
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
--
I
N
A
A
S
GRQT
V
D
E
A
L
K
D
A
Q
T
N
K
Q
-
W
Y
D
A
L
T
W
M
--
R
E
N
TPD
G
E
K
Y
D
E
----
Y
P
F
E
T
Y
G
V
I
S
W
W
-----------------------
D
Y
G
H
W
I
E
A
V
A
H
R
M
P
I
A
N
P
F
-
Q
A
G
I
G
--------
N
K
Y
N
N
V
P
G
---
A
S
S
F
F
T
A
E
N
E
-
S
Y
A
E
F
V
A
E
K
L
N
V
K
Y
V
V
S
D
I
E
M
E
T
-
G
K
Y
Y
A
M
A
V
W
----
A
E
G
D
L
P
L
A
E
K
Y
Y
G
G
Y
F
Y
----
Y
-
S
P
T
G
T
F
G
Y
A
N
S
Q
--------
W
D
I
P
L
N
S
I
I
I
P
L
R
I
P
S
E
L
Y
-----
Y
S
T
M
E
A
K
L
H
L
F
D
G
S
G
L
S
H
--------------------
Y
R
M
---
I
Y
E
S
D
Y
P
A
E
W
K
S
Y
S
S
Q
VNL
N
N
E
S
Q
V
L
Q
T
A
L
Y
E
A
V
M
R
A
R
Y
G
V
S
P
T
M
G
T
Q
E
V
L
Y
K
Y
A
--
Y
T
Q
L
Y
E
K
K
M
G
I
P
V
K
IAP
S
G
Y
V
K
I
F
-----------
E
R
V
K
G
A
V
V
T
G
K
V
S
A
N
V
T
E
V
S
V
N
A
T
I
K
T
N
Q
-
N
R
--
T
F
E
---
Y
W
Q
T
V
E
V
K
N
------
G
T
Y
T
V
V
L
PYSHNSDYP
V
K
P
I
-------
T
P
Y
H
I
K
A
G
N
V
V
K
E
I
T
I
Y
E
----
S
Q
V
Q
N
G
E
I
I
Q
L
D
L---------------------------------------------------------------------
7
PsiBlast_PDB
32.27
36%
-126
- C3 -
-
1NAS
1
SPRE_MOUSE
A:
[111-151]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
V
N
-
D
L
A
E
V
N
N
Y
--
W
A
L
-----
N
L
T
S
----
M
L
C
L
T
S
G
T
L
N
A
F
-----------------------
Q
D
S
P
G
L
S
K
T
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
29.88
19%
-59
* C2 *
-
2G9P
-
A:
[1-26]
-----------------------------------------------------------------
G
L
F
G
K
L
--
I
K
K
F
G
R
K
A
I
S
Y
A
V
K
K
A
R
G
K
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
29.36
36%
-111
- C3 -
-
1SEP
1
SPRE_MOUSE
A:
[113-153]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
V
N
-
D
L
A
E
V
N
N
Y
--
W
A
L
-----
N
L
T
S
----
M
L
C
L
T
S
G
T
L
N
A
F
-----------------------
Q
D
S
P
G
L
S
K
T
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
29.09
36%
-122
- C3 -
-
1OAA
1
SPRE_MOUSE
A:
[111-151]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
V
N
-
D
L
A
E
V
N
N
Y
--
W
A
L
-----
N
L
T
S
----
M
L
C
L
T
S
G
T
L
N
A
F
-----------------------
Q
D
S
P
G
L
S
K
T
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
17.40
19%
113
* C3 *
-
1KIL
-
CPLX1_RAT
E:
[9-49]
-----------------------------------------------------------------
K
K
E
E
E
R
--
Q
E
A
L
R
Q
A
E
E
E
R
K
A
K
Y
A
K
M
E
A
E
------
R
E
V
M
R
Q
G
I
-
R
D
K
----
Y
G
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
2.59
10%
0
- C- -
-
5IV5
-
BP06_BPT4
X:
[53-155]
---------------------------------------------------------------------------------------------------------------------
L
N
V
L
C
D
L
L
A
Y
N
T
L
------
Y
I
Q
Q
F
G
N
AAVY
E
S
F
M
R
--
T
A
N
L
RSS
V
V
Q
A
A
Q
D
N
GYL
P
T
S
K
S
--
A
A
Q
T
E
I
M
-----------
L
T
C
T
D
A
L
-
N
-
R
N
--
Y
I
T
-
I
P
-
R
G
T
R
F
L
A
Y
A
K
--
D
TS
V
N
--
P
Y
N
F
V
S
R
--
E
D
V
I
A
I
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
2.59
10%
0
- C- -
-
5IV5
-
BP06_BPT4 (first)
Y:
[53-155]
---------------------------------------------------------------------------------------------------------------------
L
N
V
L
C
D
L
L
A
Y
N
T
L
------
Y
I
Q
Q
F
G
N
AAVY
E
S
F
M
R
--
T
A
N
L
RSS
V
V
Q
A
A
Q
D
N
GYL
P
T
S
K
S
--
A
A
Q
T
E
I
M
-----------
L
T
C
T
D
A
L
-
N
-
R
N
--
Y
I
T
-
I
P
-
R
G
T
R
F
L
A
Y
A
K
--
D
TS
V
N
--
P
Y
N
F
V
S
R
--
E
D
V
I
A
I
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
2.59
10%
0
- C- -
-
5IV5
-
BP06_BPT4 (first)
A:
[53--506]
---------------------------------------------------------------------------------------------------------------------
L
N
V
L
C
D
L
L
A
Y
N
T
L
------
Y
I
Q
Q
F
G
N
A
A
V
Y
E
S
F
M
R
--
T
A
N
L
R
S
S
V
V
Q
A
A
Q
D
N
G
Y
L
P
T
S
K
S
--
A
A
Q
T
E
I
M
-----------
L
T
C
T
D
A
L
-
N
-
R
N
--
Y
I
T
-
I
P
-
R
G
T
R
F
L
A
Y
A
K
--
D
TS
V
N
--
P
Y
N
F
V
S
R
--
E
D
V
I
A
I
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------