@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VUD6: (2017-12-18 )
MQQRVIVGMSGGVDSSVSAALLLQQGYQVEGLFMKNWEEDDGTEYCTAMEDLADAQAVADKIGIKLHTANFAMEYWDRVFEHFLAEYAAGRTPNPDILCNKEIKFRAFLDHAMTLGADFIATGHYARRAETAYNSKGEAYAPLLRGLDNNKDQTYFLHAVHGREINKTLFPVGEIEKPEVRRIAEELDLATAKKKDSTGICFIGERRFNDFLKQYLPAQPGKIVLDNGKEVGEHHGLMYYTLGQRGGIGLGGMKGASEGAWFVLHKDVTNNRLVVGQGHDHPLMQSTQLWSESIDWVAGEQNIPAEGLRCTAKTRYRQPDQACTVFIDENSEHGVRVEFDEPQRAVTPGQSVVFYSDEVCLGGGVIHHTNAPTPNFI
Atome Classification :
(20 SA)
.........10........20....--....30........40........50........60...-.....70........80.....--...90........100.......-110.-.-.....120.......130.......140.......150..-......160.......170...-------....180.......190.---..--....200.......210.......220....--...230.......240.......250.......260.......270.......280.......290.......300....-.-..310.......320...-...-.330.......340.......350.......360.......370.....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MQ
Q
R
V
I
V
G
MSGGVD
S
S
V
S
A
A
L
L
L
QQ--G
Y
Q
V
E
G
L
F
MKNWEEDDG
T
E
Y
C
T
A
M
E
D
L
A
D
A
Q
A
V
A
D
KI
G
I
-
K
L
H
T
A
N
F
A
M
E
Y
W
D
R
V
F
E
H
F
L
A
E
--
Y
AAGRTPNP
D
I
L
CNKE
I
K
F
R
A
F
L
-
D
H
A
M
-
T
-L
G
A
D
F
IATGH
Y
A
R
R
A
E
TAYNSKG
E
A
Y
A
P
L
L
R
GLDNN-KD
Q
-
T
Y
F
L
H
A
VHGREINKTLFPVGEI-------E
K
P
E
V
R
R
I
A
E
E
L
D
L
A
TAK---KK--DST
G
I
C
F
I
G
E
R
R
F
N
D
F
L
K
Q
YLPAQP
G
K
I
V
LD--NGK
E
V
G
E
HH
G
L
M
Y
Y
T
LGQRGGIGLGGMKGASE
G
A
W
F
V
L
H
KDVTNN
R
L
V
V
GQGHDH
P
L
M
Q
S
T
Q
L
W
S
ESIDWVAGEQNIPAE-G-
L
R
CTAKTRYRQPDQ
A
C
T
V
-
F
I
D-ENSEH
G
V
R
V
EFDEPQRAVTPG
Q
S
V
V
F
YSD
E
V
C
LGG
G
V
I
HHTNAPTPNFI
27
HHSearch
79.09
58%
-90
- C2 -
-
2HMA
-
MNMA_STRPN
A:
[9-370]
-
K
T
R
V
V
V
G
M
S
G
G
V
D
S
S
V
T
A
L
L
L
K
E
Q
--
G
Y
D
V
I
G
I
F
M
K
N
W
D
D
T
D
----
C
T
A
T
E
D
Y
K
D
V
V
A
V
A
D
Q
I
G
I
-
P
Y
Y
S
V
N
F
E
K
E
Y
W
D
R
V
F
E
Y
F
L
A
E
--
Y
R
A
G
R
T
P
N
P
D
V
M
C
N
K
E
I
K
F
K
A
F
L
-
D
Y
A
I
-
T
-
L
G
A
D
Y
V
A
T
G
H
Y
A
R
V
A
R
D
--
E
-
D
G
T
--
V
H
M
L
R
G
V
D
N
G
-
K
D
Q
-
T
Y
F
L
S
Q
L
S
Q
E
Q
L
Q
K
T
M
F
P
L
G
H
L
-------
E
K
P
E
V
R
R
L
A
E
E
A
G
L
S
T
A
K
---
K
K
--
D
S
T
G
I
C
F
I
G
E
K
N
F
K
N
F
L
S
N
Y
L
P
A
Q
P
G
R
M
M
T
V
--
D
G
R
D
M
G
E
H
A
G
L
M
Y
Y
T
I
G
Q
R
G
G
L
G
I
G
----
G
D
N
A
P
W
F
V
V
G
K
D
L
S
K
N
I
L
Y
V
G
Q
G
F
Y
H
D
S
L
M
S
T
S
L
E
A
S
Q
V
H
F
T
R
E
M
P
--
E
E
F
-
T
-
L
E
C
T
A
K
F
R
Y
R
Q
P
D
S
K
V
T
V
-
H
V
K
-
G
---
E
K
T
E
V
I
F
A
E
P
Q
R
A
I
T
P
G
Q
A
V
V
F
Y
D
G
E
E
C
L
G
G
G
L
I
D
N
A
Y
R
D
G
----
28
HHSearch
75.35
66%
-37
- C2 -
-
2DER
-
MNMA_ECOLI
B:
[17-378]
-
A
K
K
V
I
V
G
M
S
G
G
V
D
S
S
V
S
A
W
L
L
Q
Q
Q
--
G
Y
Q
V
E
G
L
F
M
K
N
W
E
E
D
D
G
E
E
Y
C
T
A
A
A
D
L
A
D
A
Q
A
V
C
D
K
L
G
I
-
E
L
H
T
V
N
F
A
A
E
Y
W
D
N
V
F
E
L
F
L
A
E
--
Y
K
A
G
R
T
P
N
P
D
I
L
C
N
K
E
I
K
F
K
A
F
L
E
F
A
A
E
-
D
-
L
G
A
D
Y
I
A
T
G
H
Y
V
R
R
A
D
V
------
D
G
K
S
R
L
L
R
G
L
D
S
N
-
K
D
Q
-
S
Y
F
L
Y
T
L
S
H
E
Q
I
A
Q
S
L
F
P
V
G
E
L
-------
E
K
P
Q
V
R
K
I
A
E
D
L
G
L
V
T
-----------
T
G
I
C
F
I
G
E
R
K
F
R
E
F
L
G
R
Y
L
P
A
Q
P
G
K
I
I
T
V
--
D
G
D
E
I
G
E
H
Q
G
L
M
Y
H
T
L
G
Q
R
K
G
L
G
I
G
G
T
K
E
G
T
E
E
P
W
Y
V
V
D
K
D
V
E
N
N
I
L
V
V
A
Q
G
H
E
H
P
R
L
M
S
V
G
L
I
A
Q
Q
L
H
W
V
D
R
E
--
P
F
T
G
-
T
-
M
R
C
T
V
K
T
R
Y
R
Q
T
D
I
P
C
T
V
-
K
A
L
-
D
D
--
D
R
I
E
V
I
F
D
E
P
V
A
A
V
T
P
G
Q
S
A
V
F
Y
N
G
E
V
C
L
G
G
G
I
I
E
Q
R
L
P
L
-----
21
PsiBlast_CBE
74.83
65%
-19
- C2 -
-
2DEU
1
MNMA_ECOLI
B:
[18-379]
--
K
K
V
I
V
G
M
S
G
G
V
D
S
S
V
S
A
W
L
L
Q
Q
Q
--
G
Y
Q
V
E
G
L
F
M
K
N
W
E
E
D
D
G
E
E
Y
C
T
A
A
A
D
L
A
D
A
Q
A
V
C
D
K
L
G
I
-
E
L
H
T
V
N
F
A
A
E
Y
W
D
N
V
F
E
L
F
L
A
E
--
Y
K
A
G
R
T
P
N
P
D
I
L
C
N
K
E
I
K
F
K
A
F
L
-
E
F
A
A
-
E
D
L
G
A
D
Y
I
A
T
G
H
Y
V
R
R
A
D
V
D
G
K
S
R
------
L
L
R
G
L
D
S
N
-
K
D
Q
-
S
Y
F
L
Y
T
L
S
H
E
Q
I
A
Q
S
L
F
P
V
G
E
L
-------
E
K
P
Q
V
R
K
I
A
E
D
L
G
L
V
T
A
K
---
K
K
--
D
S
T
G
I
C
F
I
G
E
R
K
F
R
E
F
L
G
R
Y
L
P
A
Q
P
G
K
I
I
T
V
--
D
G
D
E
I
G
E
H
Q
G
L
M
Y
H
T
L
G
Q
R
K
G
L
G
I
G
G
T
K
E
G
T
E
E
P
W
Y
V
V
D
K
D
V
E
N
N
I
L
V
V
A
Q
G
H
E
H
P
R
L
M
S
V
G
L
I
A
Q
Q
L
H
W
V
D
R
E
---
P
F
T
-
G
T
M
R
C
T
V
K
T
R
Y
R
Q
T
D
I
P
C
T
V
K
A
L
D
-
D
D
R
---
I
E
V
I
F
D
E
P
V
A
A
V
T
P
G
Q
S
A
V
F
Y
N
G
E
V
C
L
G
G
G
I
I
E
Q
-
R
L
P
L
P
---
29
HHSearch
74.73
66%
-32
- C2 -
-
2DET
-
MNMA_ECOLI
A:
[17-378]
-
A
K
K
V
I
V
G
M
S
G
G
V
D
S
S
V
S
A
W
L
L
Q
Q
Q
--
G
Y
Q
V
E
G
L
F
M
K
N
W
E
E
D
D
G
E
E
Y
C
T
A
A
A
D
L
A
D
A
Q
A
V
C
D
K
L
G
I
-
E
L
H
T
V
N
F
A
A
E
Y
W
D
N
V
F
E
L
F
L
A
E
--
Y
K
A
G
R
T
P
N
P
D
I
L
C
N
K
E
I
K
F
K
A
F
L
E
F
A
A
E
-
D
-
L
G
A
D
Y
I
A
T
G
H
Y
V
R
R
A
D
V
------
D
G
K
S
R
L
L
R
G
L
D
S
N
-
K
D
Q
-
S
Y
F
L
Y
T
L
S
H
E
Q
I
A
Q
S
L
F
P
V
G
E
L
-------
E
K
P
Q
V
R
K
I
A
E
D
L
G
L
V
T
A
K
---
K
K
--
D
S
T
G
I
C
F
I
G
E
R
K
F
R
E
F
L
G
R
Y
L
P
A
Q
P
G
K
I
I
T
V
--
D
G
D
E
I
G
E
H
Q
G
L
M
Y
H
T
L
G
Q
R
K
G
L
G
I
G
G
T
K
E
G
T
E
E
P
W
Y
V
V
D
K
D
V
E
N
N
I
L
V
V
A
Q
G
H
E
H
P
R
L
M
S
V
G
L
I
A
Q
Q
L
H
W
V
D
R
E
--
P
F
T
G
-
T
-
M
R
C
T
V
K
T
R
Y
R
Q
T
D
I
P
C
T
V
-
K
A
L
-
D
D
--
D
R
I
E
V
I
F
D
E
P
V
A
A
V
T
P
G
Q
S
A
V
F
Y
N
G
E
V
C
L
G
G
G
I
I
E
Q
R
L
P
L
-----
2
PsiBlast_PDB
74.29
65%
-24
- C2 -
-
2DET
-
MNMA_ECOLI
A:
[18-379]
--
K
K
V
I
V
G
M
S
G
G
V
D
S
S
V
S
A
W
L
L
Q
Q
Q
--
G
Y
Q
V
E
G
L
F
M
K
N
W
E
E
D
D
G
E
E
Y
C
T
A
A
A
D
L
A
D
A
Q
A
V
C
D
K
L
G
I
-
E
L
H
T
V
N
F
A
A
E
Y
W
D
N
V
F
E
L
F
L
A
E
--
Y
K
A
G
R
T
P
N
P
D
I
L
C
N
K
E
I
K
F
K
A
F
L
-
E
F
A
A
-
E
D
L
G
A
D
Y
I
A
T
G
H
Y
V
R
R
A
D
V
D
G
K
S
R
------
L
L
R
G
L
D
S
N
-
K
D
Q
-
S
Y
F
L
Y
T
L
S
H
E
Q
I
A
Q
S
L
F
P
V
G
E
L
-------
E
K
P
Q
V
R
K
I
A
E
D
L
G
L
V
T
A
K
---
K
K
--
D
S
T
G
I
C
F
I
G
E
R
K
F
R
E
F
L
G
R
Y
L
P
A
Q
P
G
K
I
I
T
V
--
D
G
D
E
I
G
E
H
Q
G
L
M
Y
H
T
L
G
Q
R
K
G
L
G
I
G
G
T
K
E
G
T
E
E
P
W
Y
V
V
D
K
D
V
E
N
N
I
L
V
V
A
Q
G
H
E
H
P
R
L
M
S
V
G
L
I
A
Q
Q
L
H
W
V
D
R
E
---
P
F
T
-
G
T
M
R
C
T
V
K
T
R
Y
R
Q
T
D
I
P
C
T
V
K
A
L
D
-
D
D
R
---
I
E
V
I
F
D
E
P
V
A
A
V
T
P
G
Q
S
A
V
F
Y
N
G
E
V
C
L
G
G
G
I
I
E
Q
-
R
L
P
L
P
---
3
PsiBlast_PDB
73.91
65%
-19
- C2 -
-
2DEU
1
MNMA_ECOLI
A:
[18-379]
--
K
K
V
I
V
G
M
S
G
G
V
D
S
S
V
S
A
W
L
L
Q
Q
Q
--
G
Y
Q
V
E
G
L
F
M
K
N
W
E
E
D
D
G
E
E
Y
C
T
A
A
A
D
L
A
D
A
Q
A
V
C
D
K
L
G
I
-
E
L
H
T
V
N
F
A
A
E
Y
W
D
N
V
F
E
L
F
L
A
E
--
Y
K
A
G
R
T
P
N
P
D
I
L
C
N
K
E
I
K
F
K
A
F
L
-
E
F
A
A
-
E
D
L
G
A
D
Y
I
A
T
G
H
Y
V
R
R
A
D
V
D
G
K
S
R
------
L
L
R
G
L
D
S
N
-
K
D
Q
-
S
Y
F
L
Y
T
L
S
H
E
Q
I
A
Q
S
L
F
P
V
G
E
L
-------
E
K
P
Q
V
R
K
I
A
E
D
L
G
L
V
T
A
K
---
K
K
--
D
S
T
G
I
C
F
I
G
E
R
K
F
R
E
F
L
G
R
Y
L
P
A
Q
P
G
K
I
I
T
V
--
D
G
D
E
I
G
E
H
Q
G
L
M
Y
H
T
L
G
Q
R
K
G
L
G
I
G
G
T
K
E
G
T
E
E
P
W
Y
V
V
D
K
D
V
E
N
N
I
L
V
V
A
Q
G
H
E
H
P
R
L
M
S
V
G
L
I
A
Q
Q
L
H
W
V
D
R
E
---
P
F
T
-
G
T
M
R
C
T
V
K
T
R
Y
R
Q
T
D
I
P
C
T
V
K
A
L
D
-
D
D
R
---
I
E
V
I
F
D
E
P
V
A
A
V
T
P
G
Q
S
A
V
F
Y
N
G
E
V
C
L
G
G
G
I
I
E
Q
-
R
L
P
L
P
---
1
PsiBlast_PDB
72.66
65%
-17
- C2 -
-
2DER
-
MNMA_ECOLI
A:
[18-379]
--
K
K
V
I
V
G
M
S
G
G
V
D
S
S
V
S
A
W
L
L
Q
Q
Q
--
G
Y
Q
V
E
G
L
F
M
K
N
W
E
E
D
D
G
E
E
Y
C
T
A
A
A
D
L
A
D
A
Q
A
V
C
D
K
L
G
I
-
E
L
H
T
V
N
F
A
A
E
Y
W
D
N
V
F
E
L
F
L
A
E
--
Y
K
A
G
R
T
P
N
P
D
I
L
C
N
K
E
I
K
F
K
A
F
L
-
E
F
A
A
-
E
D
L
G
A
D
Y
I
A
T
G
H
Y
V
R
R
A
D
V
D
G
K
S
R
------
L
L
R
G
L
D
S
N
-
K
D
Q
-
S
Y
F
L
Y
T
L
S
H
E
Q
I
A
Q
S
L
F
P
V
G
E
L
-------
E
K
P
Q
V
R
K
I
A
E
D
L
G
L
V
---------------------
K
F
R
E
F
L
G
R
Y
L
P
A
Q
P
G
K
I
I
T
V
--
D
G
D
E
I
G
E
H
Q
G
L
M
Y
H
T
L
G
Q
R
K
G
L
G
I
G
G
T
K
E
G
T
E
E
P
W
Y
V
V
D
K
D
V
E
N
N
I
L
V
V
A
Q
G
H
E
H
P
R
L
M
S
V
G
L
I
A
Q
Q
L
H
W
V
D
R
E
---
P
F
T
-
G
T
M
R
C
T
V
K
T
R
Y
R
Q
T
D
I
P
C
T
V
K
A
L
D
-
D
D
R
---
I
E
V
I
F
D
E
P
V
A
A
V
T
P
G
Q
S
A
V
F
Y
N
G
E
V
C
L
G
G
G
I
I
E
Q
-
R
L
P
L
P
---
48
Fugue
72.28
63%
-25
- C2 -
-
2DER
-
MNMA_ECOLI
A:
[17-380]
-
A
K
K
V
I
V
G
M
S
G
G
V
D
S
S
V
S
A
W
L
L
Q
Q
Q
--
G
Y
Q
V
E
G
L
F
M
K
N
W
E
E
D
D
G
E
E
Y
C
T
A
A
A
D
L
A
D
A
Q
A
V
C
D
K
L
G
I
-
E
L
H
T
V
N
F
A
A
E
Y
W
D
N
V
F
E
L
F
L
A
E
--
Y
K
A
G
R
T
P
N
P
D
I
L
C
N
K
E
I
K
F
K
A
F
L
-
E
F
A
A
E
D
-
L
G
A
D
Y
I
A
T
G
H
Y
V
R
R
A
D
V
------
D
G
K
S
R
L
L
R
G
L
D
S
N
-
K
D
Q
-
S
Y
F
L
Y
T
L
S
H
E
Q
I
A
Q
S
L
F
P
V
G
E
L
-------
E
K
P
Q
V
R
K
I
A
E
D
---------------------
L
G
L
V
K
F
R
E
F
L
G
R
Y
L
P
A
Q
P
G
K
I
I
T
V
--
D
G
D
E
I
G
E
H
Q
G
L
M
Y
H
T
L
G
Q
R
K
G
L
G
I
G
G
T
K
E
G
T
E
E
P
W
Y
V
V
D
K
D
V
E
N
N
I
L
V
V
A
Q
G
H
E
H
P
R
L
M
S
V
G
L
I
A
Q
Q
L
H
W
V
D
R
E
P
--
F
T
G
-
T
-
M
R
C
T
V
K
T
R
Y
R
Q
T
D
I
P
C
T
V
-
K
A
L
-
D
D
D
R
--
I
E
V
I
F
D
E
P
V
A
A
V
T
P
G
Q
S
A
V
F
Y
N
G
E
V
C
L
G
G
G
I
I
E
Q
R
L
P
L
P
V
---
4
PsiBlast_PDB
71.87
56%
-73
- C2 -
-
2HMA
-
MNMA_STRPN
A:
[25-363]
-----------------
T
A
L
L
L
K
E
Q
--
G
Y
D
V
I
G
I
F
M
K
N
W
D
D
T
D
----
C
T
A
T
E
D
Y
K
D
V
V
A
V
A
D
Q
I
G
I
-
P
Y
Y
S
V
N
F
E
K
E
Y
W
D
R
V
F
E
Y
F
L
A
E
--
Y
R
A
G
R
T
P
N
P
D
V
M
C
N
K
E
I
K
F
K
A
F
L
-
D
Y
A
I
-
T
-
L
G
A
D
Y
V
A
T
G
H
Y
A
R
---
V
A
R
D
E
D
G
T
V
H
M
--
L
R
G
V
D
N
G
-
K
D
Q
-
T
Y
F
L
S
Q
L
S
Q
E
Q
L
Q
K
T
M
F
P
L
G
H
L
-------
E
K
P
E
V
R
R
L
A
E
E
A
G
L
S
T
A
K
---
K
K
--
D
S
T
G
I
C
F
I
G
E
K
N
F
K
N
F
L
S
N
Y
L
P
A
Q
P
G
R
M
M
T
V
--
D
G
R
D
M
G
E
H
A
G
L
M
Y
Y
T
I
G
Q
R
G
G
L
G
I
G
----
G
D
N
A
P
W
F
V
V
G
K
D
L
S
K
N
I
L
Y
V
G
Q
G
F
Y
H
D
S
L
M
S
T
S
L
E
A
S
Q
V
H
F
T
---
R
E
M
P
E
E
F
T
-
L
E
C
T
A
K
F
R
Y
R
Q
P
D
S
K
V
T
V
-
H
V
K
G
E
K
T
E
----
V
I
F
A
E
P
Q
R
A
I
T
P
G
Q
A
V
V
F
Y
D
G
E
E
C
L
G
G
G
L
I
-----------
34
HHSearch
38.79
20%
-81
* C2 *
-
5GHA
2
?
B:
[47-253]
-
G
E
R
V
L
V
A
V
S
G
G
K
D
S
L
A
L
W
D
V
L
S
R
L
--
G
Y
Q
A
V
G
L
H
I
E
L
G
I
G
E
------
Y
S
K
R
S
L
E
V
T
Q
A
F
A
R
E
R
G
L
-
E
L
L
V
V
D
L
K
E
A
Y
G
F
G
-
V
P
E
L
------
A
R
L
S
G
R
V
A
C
S
A
C
G
L
-
S
K
R
Y
I
I
N
-
Q
V
A
V
-
E
-
E
G
F
R
V
V
A
T
G
H
N
L
D
D
E
A
A
------
V
L
F
G
N
L
L
N
P
Q
--------
G
P
V
L
P
--
E
K
P
G
L
A
A
R
V
K
P
F
Y
R
F
-------
S
E
R
E
V
L
S
Y
T
L
L
R
G
I
R
Y
L
H
---
E
E
--
C
P
N
A
-
K
G
A
K
S
L
L
Y
K
E
A
L
N
L
V
E
R
S
M
P
G
A
K
L
R
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
38.76
22%
-61
- C2 -
-
3VRH
1
?
A:
[47-256]
-
D
E
R
I
L
V
A
V
S
G
G
K
D
S
A
V
T
A
Y
V
L
K
K
L
--
G
Y
N
I
E
C
L
H
I
N
L
G
I
S
G
------
Y
S
E
K
S
E
E
Y
A
K
K
Q
C
K
L
I
G
A
-
P
L
H
I
V
R
I
K
E
I
L
G
Y
-
G
I
G
----
E
--
V
K
--
T
R
R
P
P
C
S
Y
C
G
L
-
T
K
R
Y
I
M
N
-
K
F
A
Y
-
D
-
N
G
F
D
A
I
A
T
G
H
N
L
D
D
E
A
S
------
F
L
L
N
N
I
L
H
W
N
T
E
Y
L
A
K
G
-
G
P
I
L
-
P
Q
-
Q
G
K
F
I
K
K
V
K
P
L
Y
E
V
-------
T
E
R
E
V
V
A
Y
A
L
A
V
G
L
E
Y
I
V
---
E
E
CP
Y
-------
T
T
L
D
M
K
G
V
L
N
E
L
E
E
K
R
P
G
T
K
F
N
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
38.31
20%
-82
- C2 -
-
5GHA
1
?
C:
[47-256]
-
G
E
R
V
L
V
A
V
S
G
G
K
D
S
L
A
L
W
D
V
L
S
R
L
--
G
Y
Q
A
V
G
L
H
I
E
L
G
I
G
E
------
Y
S
K
R
S
L
E
V
T
Q
A
F
A
R
E
R
G
L
-
E
L
L
V
V
D
L
K
E
A
Y
G
F
G
-
V
P
E
L
------
A
R
L
S
G
R
V
A
C
S
A
C
G
L
-
S
K
R
Y
I
I
N
-
Q
V
A
V
-
E
-
E
G
F
R
V
V
A
T
G
H
N
L
D
D
E
A
A
------
V
L
F
G
N
L
L
N
P
Q
--------
G
P
V
L
P
--
E
K
P
G
L
A
A
R
V
K
P
F
Y
R
F
-------
S
E
R
E
V
L
S
Y
T
L
L
R
G
I
R
Y
L
H
---
E
E
--
C
------
A
K
S
L
L
Y
K
E
A
L
N
L
V
E
R
S
M
P
G
A
K
L
R
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
37.88
44%
-183
- C2 -
-
2C5S
1
THII_BACAN
A:
[189-231]
---
K
V
M
V
L
L
S
G
G
I
D
S
P
V
A
A
Y
L
T
M
K
R
--
G
V
S
V
E
A
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
HHSearch
36.81
17%
-108
- C2 -
-
3K32
1
Y690_METJA
B:
[6-162]
-
L
M
D
V
H
V
L
F
S
G
G
K
D
S
S
L
S
A
V
I
L
K
K
L
--
G
Y
N
P
H
L
I
T
I
N
F
G
V
I
----------
P
S
Y
K
L
A
E
E
T
A
K
I
L
G
F
-
K
H
K
V
I
T
L
D
R
K
I
V
E
K
A
A
D
M
I
I
E
------
H
K
Y
P
G
--
P
A
I
Q
Y
-
V
H
K
T
V
L
E
-
I
L
A
----
D
E
Y
S
I
L
A
D
G
T
R
R
D
D
R
V
P
------
K
L
---
S
Y
S
E
I
Q
S
------------
L
E
M
R
K
N
I
Q
Y
I
T
P
L
M
G
F
-------
G
Y
K
T
L
R
H
L
A
S
E
F
F
I
L
E
E
I
---
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
36.76
21%
-58
- C2 -
-
5MKO
2
?
A:
[50-260]
-
D
E
R
I
L
V
A
V
S
G
G
K
D
S
A
V
T
A
Y
V
L
K
K
L
--
G
Y
N
I
E
C
L
H
I
N
L
G
I
S
G
------
Y
S
E
K
S
E
E
Y
A
K
K
Q
C
K
L
I
G
A
-
P
L
H
I
V
R
I
K
E
I
L
G
Y
-
G
I
G
----
E
--
V
K
--
T
R
R
P
P
C
S
Y
C
G
L
-
T
K
R
Y
I
M
N
-
K
F
A
Y
-
D
-
N
G
F
D
A
I
A
T
G
H
N
L
D
D
E
A
S
------
F
L
L
N
N
I
L
H
W
N
T
E
Y
-
L
A
K
G
G
P
I
L
-
P
Q
-
Q
G
K
F
I
K
K
V
K
P
L
Y
E
V
-------
T
E
R
E
V
V
A
Y
A
L
A
V
G
L
E
Y
I
V
---
E
E
CP
Y
A
R
G
A
---
T
T
L
D
M
K
G
V
L
N
E
L
E
E
K
R
P
G
T
K
F
N
F
V
R
G
Y
L
K
K
K
-----------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
36.47
34%
-82
- C2 -
-
2E18
-
NADE_PYRHO
A:
[25-83]
----
V
V
I
G
I
S
G
G
V
D
S
A
T
V
A
Y
L
A
T
K
A
LG
K
E
K
V
L
G
L
I
M
P
Y
F
E
N
----------
K
D
V
E
D
A
K
L
V
A
E
K
L
G
I
-
G
Y
K
V
I
N
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
35.70
77%
-135
- C2 -
-
5TW7
-
GUAA_NEIG2
A:
[228-274]
----
V
I
L
G
L
S
G
G
V
D
S
S
V
A
A
A
L
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
35.52
27%
-120
- C2 -
-
3FIU
2
?
A:
[33-105]
-----
V
I
G
L
S
G
G
I
D
S
A
V
A
A
S
L
A
V
K
T
--
G
L
P
T
T
A
L
I
L
P
S
----
D
N
N
Q
H
----
Q
D
M
Q
D
A
L
E
L
I
E
M
L
N
I
-
E
H
Y
T
I
S
I
Q
P
A
Y
-----
E
A
F
L
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
35.50
17%
-100
- C2 -
-
3K32
-
Y690_METJA
A:
[6-167]
-
L
M
D
V
H
V
L
F
S
G
G
K
D
S
S
L
S
A
V
I
L
K
K
L
--
G
Y
N
P
H
L
I
T
I
N
F
G
V
I
----------
P
S
Y
K
L
A
E
E
T
A
K
I
L
G
F
-
K
H
K
V
I
T
L
D
R
K
I
V
E
K
A
A
D
M
I
I
E
------
H
K
Y
P
G
--
P
A
I
Q
Y
-
V
H
K
T
V
L
E
-
I
L
A
----
D
E
Y
S
I
L
A
D
G
T
R
R
D
D
R
V
P
------
K
L
---
S
Y
S
E
I
Q
S
------------
L
E
M
R
K
N
I
Q
Y
I
T
P
L
M
G
F
-------
G
Y
K
T
L
R
H
L
A
S
E
F
F
I
L
E
E
I
---
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
34.77
16%
-29
- C2 -
-
1VL2
-
ASSY_THEMA
A:
[2-215]
-
K
E
K
V
V
L
A
Y
S
G
G
L
D
T
S
V
I
L
K
W
L
C
E
K
--
G
F
D
V
I
A
Y
V
A
N
V
G
Q
K
----------
D
D
F
V
A
I
K
E
K
A
L
K
T
G
A
S
K
V
Y
V
E
D
L
R
R
E
F
V
T
D
Y
I
F
T
A
L
L
G
NA
M
Y
E
G
R
Y
L
L
G
T
A
I
A
R
P
-
L
I
A
K
R
Q
V
-
E
I
A
E
-
K
-
E
G
A
Q
Y
V
A
H
G
A
T
G
K
G
N
D
Q
------
V
---
R
F
E
L
T
Y
A
------------
A
L
N
-
P
N
-
L
K
V
I
S
P
W
K
D
P
E
F
L
A
K
F
K--
T
D
L
I
N
Y
A
M
E
K
G
I
P
I
K
V
SKK
R
P
--
Y
S
E
D
E
N
L
M
H
I
S
H
E
A
G
K
L
E
D
P
A
H
I
P
D
E
D
V
F
T
W
-------------------------------------------------------------------------------------------------------------------------------------------------------------