@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TZY7: (2017-12-17 )
MGTYQRSKELKIVLFLSEFSNLLPKADETPLFLCYFIFSTTFFYQRKVDKTIVK
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.-----.......20.....-.-.--.30.....-------...40.......---.50...------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGTYQRSK
E
L
K
I
-----
V
L
F
L
S
E
F
S
N
LLPKA-D-E--T
P
L
F
L
C
Y
F
-------
I
F
S
T
T
F
F
Y
QR
K
V
---
D
K
T
IVK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
65.77
27%
-44
* C6 *
-
4BB7
-
RSC2_YEAST
A:
[16-251]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HMD
E
V
I
V
NN
I
S
Y
H
VG
D
W
A
L
L
RNQNDPQK
P
I
V
G
Q
I
F
R
L
W
K
T
PDG
K
Q
W
L
N
A
C
W
Y
Y
R
PEQTVHRVD
R
L
F
Y
KN
E
V
M
K
T
G
Q
Y
R
D
H
L
V
S
N
L
V
G
K
C
Y
V
I
H
F
T
R
Y
Q
R
G
N
P
D
M
-
K
-
E
--
G
P
L
F
V
C
E
F
-------
R
Y
N
E
S
----------
D
K
I
F
N
K
I
RTWKACLPEEIRD
L
D
E
A
T
I
P
V
N
G
R
K
F
F
K
Y
P
S
PIRHLLPANATPHD
R
V
P
E
P
T
M
G
SPDAPPL
V
G
A
V
Y
M
R
P
K
M
QRDDLGEYATSDDCPRYIIRPNDSPE
E
G
Q
V
D
IETGTITT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
64.02
28%
-316
- C7 -
-
5KXI
-
?
B:
[251-295]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-----
T
V
F
L
L
L
I
S
K
I
V
P
P
T
-
S
L
D
--
V
P
L
V
G
K
Y
L
-------
M
F
T
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
63.59
21%
-48
- C2 -
-
5K7L
2
KCNH1_RAT
A:
[10-722]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVAPQNT
F
L
E
N
I
V
R
R
SND
T
N
F
V
L
G
N
AQIVDWPIVYSN
D
G
F
C
K
L
SGYHRAEVMQKSSACSFMYGELTD
K
D
T
V
E
K
V
R
Q
T
F
E
N
Y
E
M
N
S
F
E
I
L
M
Y
K
K
N
R
T
P
-----
V
W
F
F
V
K
I
A
P
I
R
N
E
Q
-
D
-
K
--
V
V
L
F
L
C
T
F
---------
S
D
I
T
A
F
K
Q
P
I
---
E
D
D
S
C
K
G
W
G
K
F
A
R
L
T
R
A
L
TSSRGVLQQLAPSVQKGENV
H
K
H
S
R
L
A
E
V
L
Q
L
G
S
D
I
LPQYKQE
A
P
K
T
P
P
HIILHYC
V
F
K
T
T
W
D
W
I
I
L
I
L
T
F
Y
T
A
I
L
V
P
Y
N
V
S
FKTRQNNV
A
W
L
V
V
D
S
I
V
D
V
I
F
L
V
D
I
V
L
N
F
H
T
T
F
V
G
PAGEVISD
P
K
L
I
R
M
N
Y
L
K
T
W
F
V
I
D
L
L
S
C
LP
Y
D
V
I
N
A
F
ENVD
E
G
I
S
S
L
F
S
S
L
KVVRLLRLGRV
A
R
K
L
D
H
Y
IEY
G
A
A
V
L
V
L
L
V
C
V
F
G
L
A
A
H
W
M
A
C
I
W
Y
S
I
G
D
Y
E
I
FDEDTKTIRNNS
W
L
Y
Q
L
A
L
D
I
G
T
P
Y
Q
F
NK
W
E
G
G
P
S
K
N
S
V
Y
I
S
S
L
Y
F
T
M
T
S
L
T
SVGFGN
I
A
P
S
T
D
I
E
K
I
F
A
V
A
I
M
M
I
G
S
L
L
Y
A
T
I
F
G
N
V
T
T
I
F
Q
Q
M
Y
A
N
T
N
R
Y
H
E
M
L
N
S
V
R
D
F
L
K
L
Y
QVP
K
G
L
S
E
R
V
M
D
Y
I
V
S
T
W
S
M
SRGID
T
E
K
V
L
Q
I
C
PK
D
M
R
A
D
I
C
V
H
L
N
R
K
V
F
K
E
HPAFRLAS
D
G
C
L
R
A
L
A
M
E
F
Q
T
V
H
C
A
PGDLIYHAGESVD
S
L
C
F
V
V
S
G
S
L
E
V
I
Q
DDEVV
A
I
L
G
K
G
D
V
F
G
D
VFWKEA
T
L
A
Q
SC
A
N
V
R
A
LTY
C
D
L
H
V
I
K
R
D
A
L
Q
K
V
L
E
F
Y
T
A
F
S
H
S
F
S
R
N
LILTYNLR
K
R
I
V
F
R
K
I
S
D
V
K
R
E
E
E
E
R
M
K
RLPP
D
H
P
V
R
R
L
F
Q
R
F
R
Q
Q
K
E
9
HHSearch
62.12
26%
-349
- C7 -
-
5KXI
-
ACHB2_HUMAN
A:
[260-298]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
F
L
L
L
I
T
E
I
I
P
S
T
-
S
-
L
V-
I
P
L
I
G
E
Y
L
-------
L
F
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
61.91
32%
0
- C- -
-
2BG9
-
?
C:
[268-396]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
F
L
L
L
T
S
Q
R
L
P
E
T
-
A
L
A
--
V
P
L
I
G
K
Y
L
-------
M
F
I
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
53.39
16%
62
- C5 -
-
1JBK
-
CLPB_ECOLI
A:
[1-195]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HM
Q
A
L
K
K
YTID
L
T
E
R
A
E
Q
GKLDPVIGR
D
E
E
I
R
R
T
I
Q
V
L
Q
RRTKN
N
P
V
L
I
G
E
PGVG
K
T
A
I
V
E
G
L
A
Q
R
I
I
N
GEVPEGLKG
R
R
V
L
A
LD
M
G
A
L
V
AGAKY
R
G
E
F
E
E
R
L
K
G
V
L
N
D
L
A
K
Q
E
G
N
V
-----
I
L
F
I
D
E
L
H
T
M
V
G
A
M
-
D
-
A
--
G
N
M
L
K
P
A
L
A
R
GE
L
H
C
V
G
A
T
T
L
D
E
Y
R
Q
Y
IEK
D
A
A
L
E
R
R
F
Q
K
V
F
V
A
EPS
V
E
D
T
I
AILR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
47.11
22%
111
* C7 *
-
5MQF
-
SYF2_HUMAN
N:
[128-242]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAAQLRQYHRLTKQIKPD
M
E
T
Y
E
R
L
R
E
K
H
G
-----
E
E
F
F
P
T
S
N
S
L
L
H
G
T
-
H
-
V
--
P
S
---------------------
T
E
E
I
---
D
R
M
V
I
D
LEKQIEKRDKYSRRRPYNDDADIDYINERNAKFNKKAERFYGKYTAEIKQNLERGTA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
47.06
29%
0
- C- -
-
2BG9
-
?
E:
[262-389]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
F
L
F
L
I
A
Q
K
V
P
E
T
-
S
-
L
N-
V
P
L
I
G
K
Y
L
-------
I
F
V
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
45.39
16%
64
- C6 -
-
5CMN
-
AGRL3_HUMAN
E:
[3-260]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LCPGLLKGVYQSEHLFESDHQSGAWCKDPLQASDKIYYMPWTPYRTDT
L
T
E
Y
S
S
K
D
D
F
I
A
-----
G
R
P
T
T
T
Y
K
-
L
P
H
R
V
-
D
-
G
--
T
G
----
F
V
-------
V
Y
D
G
A
L
F
F
N
K
E
R
---
T
R
N
I
V
K
FDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVDENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYSLDF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
43.88
22%
0
- C- -
-
2BG9
-
?
B:
[260-377]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
F
L
L
L
L
A
D
K
V
P
E
T
-
S
-
L
S-
V
P
I
I
I
S
Y
L
-------
M
F
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
43.25
29%
0
- C- -
-
2BG9
-
ACHA_TORMA
A:
[254-349]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
F
L
L
V
I
V
E
L
I
P
S
T
S
S
-
A
--
V
P
L
I
G
K
Y
M
-------
L
F
T
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
HHSearch
41.55
32%
-132
- C7 -
-
2E9K
-
A:
[99-120]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
S
M
-----
V
M
Y
L
S
K
F
Y
E
L
F
R
G
T
-
P
-
L
--
R
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
40.18
16%
-1
- C7 -
-
1IQ0
-
SYR_THET8
A:
[1-592]
ML
R
R
A
L
E
E
A
I
A
Q
A
L
K
E
M
GVP
V
R
L
K
V
A
RAPKDKPGD
Y
G
V
P
LFALAKELRKP
P
Q
A
I
A
Q
E
L
K
D
R
LPLPEFVE
E
A
V
P
V
GG
Y
L
N
F
R
L
R
T
E
A
L
L
R
E
A
L
RPKAPF
P
R
R
P
G
V
V
L
V
E
H
TSVNPN
K
E
L
H
VGH
L
R
N
I
A
L
G
D
A
I
A
R
I
L
A
Y
A
GRE
V
L
V
L
N
Y
I
DDTG
R
Q
A
A
E
T
L
F
A
L
R
H
Y
GLTWDGKEK
Y
D
H
F
A
G
R
A
Y
V
R
L
H
Q
DPEYERL
Q
P
A
I
E
E
V
L
H
A
L
E
R
GEL
R
E
E
V
N
R
I
L
L
A
Q
M
A
T
M
H
A
L
NARYD
L
L
V
W
E
S
D
I
V
R
A
G
L
L
Q
K
A
L
A
L
L
E
Q
SPH
V
F
R
P
REGKYAG
A
L
V
M
D
ASPVIPGLEDPFFVLLRSNGTAT
Y
Y
A
K
D
I
A
F
Q
F
W
K
M
GILEG
L
R
F
R
P
YENPYYPG
L
R
T
S
A
PEGEAYTPKAE
E
T
I
N
V
V
D
VRQSHPQ
A
L
V
R
A
A
L
A
L
A
GY
P
A
L
A
E
K
AHHL
A
Y
E
T
V
L
L
EGRQMSGAVS
V
D
E
V
L
E
E
A
T
R
R
A
R
A
I
V
E
E
K
N
PDHPD
K
E
E
A
A
R
M
V
A
L
G
A
I
R
F
S
M
V
KTEPK
K
Q
I
D
F
R
Y
Q
E
A
L
SFEGDT
G
P
Y
V
Q
Y
A
H
A
R
A
H
S
I
L
R
K
A
GEWGAPD
L
S
Q
A
-
T
P
Y
E
R
A
L
-----
A
L
D
L
L
D
F
E
E
A
V
L
E
A
-
A
-
E
E
R
T
P
H
V
L
A
Q
Y
-------
L
L
D
L
A
A
S
W
N
A
Y
Y
---
N
A
R
E
N
G
QPATPVLTAPE
G
L
R
E
L
R
L
S
L
V
Q
S
L
Q
R
T
L
A
T
G
L
D
L
L
G
I
P
A
P
EVM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
36.81
64%
-13
- C1 -
-
1S5Q
-
B:
[79-89]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
E
F
G
Q
F
L
P
D
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
36.10
25%
-401
- C4 -
-
4AG6
-
?
B:
[258-277]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
R
R
E
R
T
-----
V
L
V
V
D
E
A
W
M
L
V
D
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
35.46
23%
-178
- C7 -
-
2CR7
-
SIN3B_MOUSE
A:
[65-77]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
V
G
F
N
A
F
L
P
S
G
-
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
32.35
42%
-77
- C7 -
-
2IBF
-
D:
[5-23]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
E
K
A
K
E
V
S
----------
S
A
L
S
K
V
L
S
K
I
-
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
32.19
28%
47
- C7 -
-
2IBF
-
IPAA_SHIFL
B:
[1-25]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
H
A
I
Y
E
K
A
-----
K
E
V
S
S
A
L
S
K
V
L
S
K
I
-
D
-
D
--
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
30.82
30%
36
- C7 -
-
2HSQ
-
B:
[1-23]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
Y
E
K
A
-----
K
E
V
S
S
A
L
S
K
V
L
S
K
I
-
D
-
D
--
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
30.21
17%
-570
- C3 -
-
2K06
-
NUSG_ECOLI
A:
[58-75]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
K
-
S
-
E
--
R
K
F
F
P
G
Y
V
-------
L
V
Q
M
V
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------