@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3U2Q2: (2017-12-23 )
MMSNSSVIDAMCYNNSVKSKMKWRKDMDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGVLPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDEVMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDEVTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEVAQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIALFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE
Atome Classification :
(22 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......-240......---.---------250--------.---------...----....260-.......270-........280.......290...--.-..--.300-.-.-.-.....310..--.....320-.........330.-----
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MMSNS
S
V
I
D
A
M
CYNN
S
V
K
S
K
M
K
W
R
KD
M
D
G
L
L
P
L
W
K
ERGMT
S
H
D
C
V
F
K
L
R
K
I
L
H
TKKIGHGGTLDPDVD
G
V
L
P
I
CIG
K
A
T
K
V
I
E
Y
LTDSG
K
I
Y
V
G
E
I
T
L
GFSTTTEDRSGERVETKPVDM
S
L
S
E
K
K
I
D
E
V
M
A
S
F
I
G
E
I
TQIPPMY
S
A
V
KVN
G
K
R
L
Y
E
Y
ARNN
E
T
V
E
R
P
V
R
K
A
Q
I
Y
R
F
I
R
T
SELTRDE
V
T
G
T
I
S
W
R
F
E
V
ECGK
G
T
Y
V
R
T
L
AVDTGKKLGYP
A
H
M
S
D
L
T
R
T
A
SAGMSQKDAL-
T
L
E
E
V
A
Q
A
V
---K---------NG---------T---------I
D
D
----
C
L
L
P
I
E
K
-
G
V
E
R
F
KRVD--I
T
D
E
V
W
Q
K
V
KNG
M
R
L
D
Y
T
V
F
ALPE--M-PS--E
E
-
I
-
A
-
L
-
F
-YK
G
K
V
V
S
I
YQ--PNPKEK---NKL
K
P
S
K
VLRNEE-----
31
Fugue
92.31
33%
-71
- C3 -
-
1R3E
3
TRUB_THEMA
A:
[1-309]
-------------------------
M
K
H
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
Y
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
E
C
--
N
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
D
V
N
I
E
G
R
-------
D
V
S
F
R
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
E
S
L
-
N
V
F
E
A
-------
A
---------
P
E
---------
E
---------
I
E
N
----
R
I
I
P
L
E
K
-
C
L
E
W
L
P
R
V
V
--
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
I
H
L
E
M
L
K
E
W
D
GF
K
-
K
G
--
E
V
-
V
-
R
-
V
-
F
N
E
E
G
R
L
L
A
L
A
E
A
E
R
N
S
S
F
L
---
E
T
L
R
K
E
R
V
L
T
L
R
K
VFNTR
39
HHSearch
90.36
33%
-80
- C3 -
-
1R3E
3
TRUB_THEMA
A:
[1-288]
-------------------------
M
K
H
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
Y
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
E
--
C
N
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
D
V
N
I
E
-------
G
R
D
V
S
F
R
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
E
S
L
-
N
V
F
E
A
A
P
E
E
----------------------------------
I
E
N
----
R
I
I
P
L
E
K
-
C
L
E
W
L
P
R
V
V
--
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
I
H
L
E
M
L
K
-
E
W
--
D
-
G
F
KK
G
E
V
V
R
V
-
F
-
N
-
E
E
G
R
L
L
A
L
A
E
--
A
E
R
N
S
----------------------
3
PsiBlast_PDB
89.05
34%
-102
- C3 -
-
1R3E
3
TRUB_THEMA
A:
[4-273]
----------------------------
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
Y
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
--
E
C
N
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
D
V
N
I
E
G
R
D
-----
V
S
F
R
--
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
E
S
L
-
N
V
F
E
A
A
P
E
-------------------------
E
---------
I
E
N
----
R
I
I
P
L
E
K
-
C
L
E
W
L
P
R
V
V
--
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
I
H
L
E
M
L
------------
K
E
-
W
-
D
-
G
-
F
-
K
K
G
E
V
V
R
V
F
N
-----------------------------
38
HHSearch
88.97
33%
-54
- C3 -
-
1K8W
1
TRUB_ECOLI
A:
[22-325]
------------------------
M
D
I
N
G
V
L
L
L
D
K
P
Q
G
M
S
S
N
D
A
L
Q
K
V
K
R
I
Y
N
A
N
R
A
G
H
T
G
A
L
D
P
L
A
T
G
M
L
P
I
C
L
G
E
A
T
K
F
S
Q
Y
L
L
D
S
D
K
R
Y
R
V
I
A
R
L
G
Q
R
T
D
T
S
D
A
D
G
Q
I
V
E
E
R
P
V
--
T
F
S
A
E
Q
L
A
A
A
L
D
T
F
R
G
D
I
E
Q
I
P
S
M
Y
S
A
L
K
Y
Q
G
K
K
L
Y
E
Y
A
R
Q
G
I
E
V
P
R
E
A
R
P
I
T
V
Y
E
L
L
F
I
R
H
E
-------
G
N
E
L
E
L
E
I
H
C
S
K
G
T
Y
I
R
T
I
I
D
D
L
G
E
K
L
G
C
G
A
H
V
I
Y
L
R
R
L
A
V
S
K
Y
P
V
E
R
M
V
-
T
L
E
H
L
R
E
L
V
---
E
Q
A
E
Q
Q
DIP
A
A
E
---------
L
---------
L
D
P
----
L
L
M
P
M
D
S
-
P
A
S
D
Y
P
V
V
N
--
L
P
L
T
S
S
V
Y
F
K
N
G
N
P
V
R
T
S
G
A
P
L
-
E
--------
G
L
-
V
-
R
V
T
E
G
-
E
N
G
K
F
I
G
M
G
E
--
I
D
D
E
G
-----
R
V
A
P
R
R
L
V
V
E
Y
------
29
Fugue
88.29
33%
-48
- C3 -
-
1K8W
1
TRUB_ECOLI
A:
[22-324]
------------------------
M
D
I
N
G
V
L
L
L
D
K
P
Q
G
M
S
S
N
D
A
L
Q
K
V
K
R
I
Y
N
A
N
R
A
G
H
T
G
A
L
D
P
L
A
T
G
M
L
P
I
C
L
G
E
A
T
K
F
S
Q
Y
L
L
D
S
D
K
R
Y
R
V
I
A
R
L
G
Q
R
T
D
T
S
D
A
D
G
Q
I
V
E
E
R
P
V
--
T
F
S
A
E
Q
L
A
A
A
L
D
T
F
R
G
D
I
E
Q
I
P
S
M
Y
S
A
L
K
Y
Q
G
K
K
L
Y
E
Y
A
R
Q
G
I
E
V
P
R
E
A
R
P
I
T
V
Y
E
L
L
F
I
R
H
E
G
N
-------
E
L
E
L
E
I
H
C
S
K
G
T
Y
I
R
T
I
I
D
D
L
G
E
K
L
G
C
G
A
H
V
I
Y
L
R
R
L
A
V
S
K
Y
P
V
E
R
M
V
-
T
L
E
H
L
R
E
L
V
---
E
---------
Q
A
---------
E
Q
Q
DIP
A
A
E
L
L
D
P
----
L
L
M
P
M
D
S
-
P
A
S
D
Y
P
V
V
N
--
L
P
L
T
S
S
V
Y
F
K
N
G
N
P
V
R
T
S
--
G
A
P
L
--
E
-
G
L
--
V
R
-
V
-
T
-
E
-
G
-
E
N
G
K
F
I
G
M
G
E
--
I
D
--
D
E
---
G
R
V
A
P
R
R
L
V
V
E
-------
2
PsiBlast_PDB
86.06
36%
-70
- C3 -
-
1K8W
1
TRUB_ECOLI
A:
[23-284]
-------------------------
D
I
N
G
V
L
L
L
D
K
P
Q
G
M
S
S
N
D
A
L
Q
K
V
K
R
I
Y
N
A
N
R
A
G
H
T
G
A
L
D
P
L
A
T
G
M
L
P
I
C
L
G
E
A
T
K
F
S
Q
Y
L
L
D
S
D
K
R
Y
R
V
I
A
R
L
G
Q
R
T
D
T
S
D
A
D
G
Q
I
V
E
E
R
P
V
--
T
F
S
A
E
Q
L
A
A
A
L
D
T
F
R
G
D
I
E
Q
I
P
S
M
Y
S
A
L
K
Y
Q
G
K
K
L
Y
E
Y
A
R
Q
G
I
E
V
P
R
E
A
R
P
I
T
V
Y
E
L
L
----
F
I
R
H
E
G
N
---
E
L
E
L
E
I
H
C
S
K
G
T
Y
I
R
T
I
I
D
D
L
G
E
K
L
G
C
G
A
H
V
I
Y
L
R
R
L
A
V
S
K
Y
P
V
E
R
M
V
-
T
L
E
H
L
R
E
L
V
---
E
---------
Q
A
E
Q
Q
DIP
A
A
E
L
---------
L
D
P
----
L
L
M
P
M
D
S
-
P
A
S
D
Y
P
V
V
N
L
P
L
T
S
S
V
Y
F
K
N
G
N
P
V
R
--------------------------------------------------------------------
6
PsiBlast_PDB
85.63
36%
-68
- C3 -
-
1ZL3
1
TRUB_ECOLI
A:
[23-284]
-------------------------
D
I
N
G
V
L
L
L
D
K
P
Q
G
M
S
S
N
D
A
L
Q
K
V
K
R
I
Y
N
A
N
R
A
G
H
T
G
A
L
N
P
L
A
T
G
M
L
P
I
C
L
G
E
A
T
K
F
S
Q
Y
L
L
D
S
D
K
R
Y
R
V
I
A
R
L
G
Q
R
T
D
T
S
D
A
D
G
Q
I
V
E
E
R
P
V
--
T
F
S
A
E
Q
L
A
A
A
L
D
T
F
R
G
D
I
E
Q
I
P
S
M
Y
S
A
L
K
Y
Q
G
K
K
L
Y
E
Y
A
R
Q
G
I
E
V
P
R
E
A
R
P
I
T
V
Y
E
L
L
----
F
I
R
H
E
G
N
---
E
L
E
L
E
I
H
C
S
K
G
T
Y
I
R
T
I
I
D
D
L
G
E
K
L
G
C
G
A
H
V
I
Y
L
R
R
L
A
V
S
K
Y
P
V
E
R
M
V
-
T
L
E
H
L
R
E
L
V
---
E
---------
Q
A
E
Q
Q
DIP
A
A
E
L
---------
L
D
P
----
L
L
M
P
M
D
S
-
P
A
S
D
Y
P
V
V
N
L
P
L
T
S
S
V
Y
F
K
N
G
N
P
V
R
--------------------------------------------------------------------
4
PsiBlast_PDB
85.48
34%
-103
- C3 -
-
1ZE2
2
TRUB_THEMA
A:
[4-277]
----------------------------
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
Y
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
--
E
C
N
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
D
V
N
I
E
G
R
D
-----
V
S
F
R
--
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
E
S
L
-
N
V
F
E
A
A
P
E
-------------------------
E
---------
I
E
N
----
R
I
I
P
L
E
K
-
C
L
E
W
L
P
R
V
V
--
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
I
H
L
E
M
L
------------
K
E
-
W
-
D
-
G
-
F
-
K
K
G
E
V
V
R
V
F
N
-----------------------------
7
PsiBlast_PDB
84.49
34%
-106
- C3 -
-
2AB4
1
TRUB_THEMA
A:
[4-277]
----------------------------
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
F
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
--
E
C
N
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
D
V
N
I
E
G
R
D
-----
V
S
F
R
--
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
E
S
L
-
N
V
F
E
A
A
P
E
-------------------------
E
---------
I
E
N
----
R
I
I
P
L
E
K
-
C
L
E
W
L
P
R
V
V
--
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
I
H
L
E
M
L
------------
K
E
-
W
-
D
-
G
-
F
-
K
K
G
E
V
V
R
V
F
N
-----------------------------
5
PsiBlast_PDB
84.41
34%
-98
- C3 -
-
1ZE1
-
TRUB_THEMA
A:
[4-269]
----------------------------
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
Y
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
--
E
C
N
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
D
V
N
I
E
G
R
D
-----
V
S
F
R
--
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
E
S
L
-
N
V
F
E
A
A
P
E
-------------------------
E
---------
I
E
N
----
R
I
I
P
L
E
K
-
C
L
E
W
L
P
R
V
V
--
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
I
H
L
E
M
L
------------
K
E
-
W
-
D
-
G
-
F
-
K
K
G
E
V
V
R
V
F
N
-----------------------------
40
HHSearch
84.28
33%
-77
- C3 -
-
1ZE1
-
TRUB_THEMA
B:
[1-284]
-------------------------
M
K
H
G
I
L
V
A
Y
K
P
K
G
P
T
S
H
D
V
V
D
E
V
R
K
K
L
K
T
R
K
V
G
H
G
G
T
L
D
P
F
A
C
G
V
L
I
I
G
V
N
Q
G
T
R
I
L
E
F
Y
K
D
L
K
K
V
Y
W
V
K
M
R
L
G
L
I
T
E
T
F
D
I
T
G
E
V
V
E
E
R
E
--
C
N
V
T
E
E
E
I
R
E
A
I
F
S
F
V
G
E
Y
D
Q
V
P
P
A
Y
S
A
K
K
Y
K
G
E
R
L
Y
K
L
A
R
E
G
K
I
I
N
L
P
P
K
R
V
K
I
F
K
I
W
D
V
N
I
E
-------
G
R
D
V
S
F
R
V
E
V
S
P
G
T
Y
I
R
S
L
C
M
D
I
G
Y
K
L
G
C
G
A
T
A
V
E
L
V
R
E
S
V
G
P
H
T
I
E
E
S
L
-
N
V
F
E
A
A
P
E
E
----------------------------------
I
E
N
----
R
I
I
P
L
E
K
-
C
L
E
W
L
P
R
V
V
--
V
H
Q
E
S
T
K
M
I
L
N
G
S
Q
I
H
L
E
M
L
K
E
W
D
G-
F
K
K
G
--
E
V
-
V
R
V
-
F
-
N
-
E
E
G
R
L
L
A
L
A
E
--
A
E
R
N
S
----------------------
37
HHSearch
80.92
34%
-78
- C3 -
-
1SGV
-
TRUB_MYCTU
B:
[3-294]
------------------------
A
T
G
P
G
I
V
V
I
D
K
P
A
G
M
T
S
H
D
V
V
G
R
C
R
R
I
F
A
T
R
R
V
G
H
A
G
T
L
D
P
M
A
T
G
V
L
V
I
G
I
E
R
A
T
K
I
L
G
L
L
T
A
A
P
K
S
Y
A
A
T
I
R
L
G
Q
T
T
S
T
E
D
A
E
G
Q
V
L
Q
S
V
P
A
-
K
H
L
T
I
E
A
I
D
A
A
M
E
R
L
R
----------------------------
S
V
Q
L
E
A
R
P
I
R
I
D
R
F
E
L
L
A
A
R
R
R
D
---
Q
L
I
D
I
D
V
E
I
D
C
S
S
G
T
Y
I
R
A
L
A
R
D
L
G
D
A
L
G
V
G
G
H
V
T
A
L
R
R
T
R
V
G
R
F
E
L
D
Q
A
R
-
S
L
D
D
L
A
E
R
P
------------------------------------
A
----
L
S
L
S
L
D
E
A
C
L
L
M
F
A
R
R
D
--
L
T
A
A
E
A
S
A
A
A
N
G
R
S
L
P
A
V
G
I
D
G
V
Y
-----------
A
-
A
-
C
-
D
-
A
D
G
R
V
I
A
L
L
R
--
D
E
G
S
R
T
R
S
V
A
V
L
R
P
A
T
-----------
13
PsiBlast_PDB
79.52
34%
-93
- C3 -
-
3LWP
-
TRUB_PYRFU
A:
[47-269]
----------------------------
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
---------------------------
L
R
T
R
K
V
Y
-
Y
I
E
V
L
E
I
E
G
R
D
V
L
------
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
E
T
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
---------
E
D
---------
G
---------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
-
A
V
E
H
L
P
K
V
W
--
I
K
D
S
A
V
A
A
V
T
H
G
A
D
L
-------------------------------------------------------------------
11
PsiBlast_PDB
79.38
34%
-81
- C3 -
-
3HAY
1
TRUB_PYRFU
A:
[47-269]
----------------------------
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
P
P
L
R
S
A
V
K
-----------------
R
R
L
R
T
R
K
V
Y
-
Y
I
E
V
L
E
I
E
G
R
D
V
L
------
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
E
T
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
---------
E
D
---------
G
---------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
-
A
V
E
H
L
P
K
V
W
--
I
K
D
S
A
V
A
A
V
T
H
G
A
D
L
-------------------------------------------------------------------
9
PsiBlast_PDB
79.29
34%
-91
- C3 -
-
2HVY
1
TRUB_PYRFU
A:
[47-269]
----------------------------
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
P
P
L
------------------------
L
R
T
R
K
V
Y
-
Y
I
E
V
L
E
I
E
G
R
D
V
L
------
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
E
T
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
---------
E
D
---------
G
---------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
-
A
V
E
H
L
P
K
V
W
--
I
K
D
S
A
V
A
A
V
T
H
G
A
D
L
-------------------------------------------------------------------
20
PsiBlast_PDB
79.23
34%
-85
- C3 -
-
3HJY
2
TRUB_PYRFU
A:
[40-262]
----------------------------
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
P
P
L
------------------------
L
R
T
R
K
V
Y
-
Y
I
E
V
L
E
I
E
G
R
D
V
L
------
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
E
T
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
---------
E
D
---------
G
---------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
-
A
V
E
H
L
P
K
V
W
--
I
K
D
S
A
V
A
A
V
T
H
G
A
D
L
-------------------------------------------------------------------
19
PsiBlast_PDB
79.07
34%
-83
- C3 -
-
3HJW
1
TRUB_PYRFU
A:
[40-262]
----------------------------
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
P
P
L
R
S
A
V
K
-----------------
R
R
L
R
T
R
K
V
Y
-
Y
I
E
V
L
E
I
E
G
R
D
V
L
------
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
E
T
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
---------
E
D
---------
G
---------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
-
A
V
E
H
L
P
K
V
W
--
I
K
D
S
A
V
A
A
V
T
H
G
A
D
L
-------------------------------------------------------------------
12
PsiBlast_PDB
79.07
34%
-90
- C3 -
-
3LWO
1
TRUB_PYRFU
A:
[47-269]
----------------------------
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
---------------------------
L
R
T
R
K
V
Y
-
Y
I
E
V
L
E
I
E
G
R
D
V
L
------
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
E
T
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
---------
E
D
---------
G
---------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
-
A
V
E
H
L
P
K
V
W
--
I
K
D
S
A
V
A
A
V
T
H
G
A
D
L
-------------------------------------------------------------------
16
PsiBlast_PDB
78.74
34%
-87
- C3 -
-
3LWV
1
TRUB_PYRFU
A:
[47-269]
----------------------------
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
---------------------------
L
R
T
R
K
V
Y
-
Y
I
E
V
L
E
I
E
G
R
D
V
L
------
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
E
T
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
---------
E
D
---------
G
---------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
-
A
V
E
H
L
P
K
V
W
--
I
K
D
S
A
V
A
A
V
T
H
G
A
D
L
-------------------------------------------------------------------
18
PsiBlast_PDB
78.68
34%
-94
- C3 -
-
3MQK
2
TRUB_PYRFU
A:
[40-262]
----------------------------
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
P
P
L
R
S
A
V
K
-----------------
R
R
L
R
T
R
K
V
Y
-
Y
I
E
V
L
E
I
E
G
R
D
V
L
------
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
E
T
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
---------
E
D
---------
G
---------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
-
A
V
E
H
L
P
K
V
W
--
I
K
D
S
A
V
A
A
V
T
H
G
A
D
L
-------------------------------------------------------------------
15
PsiBlast_PDB
77.60
34%
-88
- C3 -
-
3LWR
1
TRUB_PYRFU
A:
[47-269]
----------------------------
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
---------------------------
L
R
T
R
K
V
Y
-
Y
I
E
V
L
E
I
E
G
R
D
V
L
------
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
E
T
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
---------
E
D
---------
G
---------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
-
A
V
E
H
L
P
K
V
W
--
I
K
D
S
A
V
A
A
V
T
H
G
A
D
L
-------------------------------------------------------------------
10
PsiBlast_PDB
75.91
34%
-81
- C3 -
-
3HAX
5
TRUB_PYRFU
A:
[47-269]
----------------------------
G
V
I
N
L
D
K
P
P
G
P
T
S
H
E
V
V
A
W
I
K
K
I
L
N
L
E
K
A
G
H
G
G
T
L
D
P
K
V
S
G
V
L
P
V
A
L
E
K
A
T
R
V
V
Q
A
L
L
P
A
G
K
E
Y
V
A
L
M
H
L
-------------------
H
G
D
V
P
E
D
K
I
I
Q
V
M
K
E
F
E
G
E
I
I
Q
R
P
P
L
R
S
A
V
K
-----------------
R
R
L
R
T
R
K
V
Y
-
Y
I
E
V
L
E
I
E
G
R
D
V
L
------
F
R
V
G
V
E
A
G
T
Y
I
R
S
L
I
H
H
I
G
L
A
L
G
V
G
A
H
M
S
E
L
R
R
T
R
S
G
P
F
K
E
D
E
T
L
I
T
L
H
D
L
V
D
Y
Y
Y
F
W
K
---------
E
D
---------
G
---------
I
E
E
Y
F
R
K
A
I
Q
P
M
E
K
-
A
V
E
H
L
P
K
V
W
--
I
K
D
S
A
V
A
A
V
T
H
G
A
D
L
-------------------------------------------------------------------