@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XYC7: (2018-01-08 )
MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHFAHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLAIEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVHCWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEKVSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLYRMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK
Atome Classification :
(20 SA)
----.........10........20........30.......-.40......---..50........60........-------70.......----.80--.--......--.90.......-------.--100.........110----.----.......120.--...--..--.130...-----....140.--....-----..150.......160.......170.......180.......190-.........200.---......210.....--..220.......230.......240--.......250.......260.......270......---.280.......290...-------------....300.......310.......320.......330-----
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----
M
L
L
A
MNEY
N
K
C
C
F
A
K
H
A
EKG
K
K
Y
Y
C
R
G
C
R
K
R
V
I
L
K
K
G
K
-
K
K
C
A
H
F
A
HQ---KSDNC
S
V
F
S
E
RE
S
K
E
H
L
Q
L
K
E
C
-------
F
M
D
W
LGQSV----
E
P
V
--
F
--
L
E
A
Y
L
P
--
R
LRQRP
D
I
L
L
-------
A
--
N
--
L
A
I
E
I
Q
C
S
RL
S
-----
H
----
Q
R
F
I
E
R
T
Q
N
Y
L--NNS--
Y
Q
--
V
W
W
I
LGN-----SFLG
Q
S
Q
F
--
S
L
I
E
-----
K
S
C
C
YYNRKRGV
H
C
W
K
ADLKKQ
K
L
Y
L
Y
H
H
I
T
E
TV
S
G
H
I
S
F
C
S
S---CWTFS
S
R
D
L
K
E
I
F---TSNEI
K
M
N
Q
M
K
K
I
E
--
K
V
S
ED
G
K
K
W
L
T
R
Q
L
I
H
KQKNT
V
S
I
Q
--
E
Q
C
Y
L
R
H
K
H
L
L
H
L
S
S
W
I
Y
QK
S
R
F
F
F
Y
L
Q
E
Q
V
F
L
Y
R
M
---
L
Y
E
E
A
LENQKVP
D
F
N
S
W
-------------
L
C
Q
I
K
E
H
K
R
EWLFPMI
D
E
E
M
V
Y
Q
Q
F
F
N
E
C
I
H
L
S
SLKK-----
31
Fugue
60.92
16%
-22
- C6 -
-
2V9P
-
VE1_BPV1
A:
[1-279]
-----
T
L
N
E
S
K
F
D
F
G
T
M
V
Q
W
A
Y
D
H
K
Y
A
E
E
S
K
I
A
Y
E
Y
A
L
A
A
G
S
D
S
N
A
R
A
F
L
A
T
---
N
S
-----
Q
A
K
H
V
K
D
C
A
T
M
V
R
H
Y
-------
L
R
A
E
T
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A
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S
----
M
P
A
--
Y
--
I
K
A
R
C
K
--
L
A
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E
G
S
W
K
S
-------
I
--
L
--
T
F
F
N
Y
Q
--
N
I
E
-----
L
----
I
T
F
I
N
A
L
K
L
W
L
--
K
G
I
PK
K
N
--
C
L
A
F
I
G
P
-----
P
N
T
G
K
S
M
L
C
N
S
L
I
H
F
L
---
G
G
S
V
L
S
F
A
N
H
K
S
H
F
W
L
A
S
L
A
D
T
R
A
A
L
V
D
D
A
T
----------
H
A
---
C
W
R
Y
F
D
T
Y
L
R
N
A
L
---
D
G
Y
P
V
S
I
D
R
-----------------------
K
H
K
A
A
V
Q
I
--------
K
A
P
P
L
L
V
T
S
N
I
D
V
Q
A
E
D
R
Y
L
Y
L
H
S
R
V
Q
T
F
R
-----
F
E
Q
P
C
T
D
E
Q
P
F
N
I
T
---------------------------------
D
A
D
W
K
S
F
F
V
R
L
W
G
R
L
D
L
I
D
-----
23
Fugue
60.54
19%
15
- C3 -
-
5CXB
1
B:
[1-369]
PSPD
E
L
K
P
F
P
T
V
Q
Q
T
I
F
R
G
H
E
G
R
--------
V
R
S
V
A
I
D
P
T
G
V
----
A
L
A
T
G
G
---
D
D
G
T
V
R
V
W
E
L
L
T
G
R
Q
V
W
S
V
K
----------
L
N
G
-
D
E
A
V
----
N
T
V
--
R
--
W
-------
R
P
T
K
D
T
F
I
L
A
-------
A
--
A
--
A
G
E
D
I
F
L
M
I
P
T
-----
H
PSVT
P
A
L
D
Q
A
S
R
D
I
L
--
N
A
G
--
F
P
P
G
K
W
A
R
P
G
T
-----
R
L
E
D
E
G
V
L
--
L
R
I
T
V
RSTI
K
A
I
S
W
H
--
R
R
G
D
H
F
A
T
V
S
P
S
G
Q
R
S
S
V
A
I
H
T
L
S
K
H
L
T
Q
I
P
F
R
K
L
NGL
A
Q
T
A
S
F
H
P
L
R
P
L
F
F
V
A
T
Q
R
S
I
R
C
Y
D
L
Q
K
L
E
LV
K
I
V
Q
P
G
A
K
W
I
S
S
F
D
V
H
P
G
G
D
N
L
V
V
G
S
Y
D
K
R
L
L
W
H
D
--
L
D
L
S
N
R
P
Y
K
T
M
R
F
H
T
E
A
I
R
A
V
R
F
H
K
G
GLP
L
F
A
D
A
S
D
D
G
S
L
Q
I
F
H
G
K
V
P
NDQL
E
N
P
T
I
V
P
V
K
M
L
K
G
H
K
V
V
N
K
L
G
V
L
D
I
D
W
H
P
R
E
P
W
--
C
V
S
A
G
A
D
G
T
A
R
L
W
M
30
Fugue
60.49
15%
-49
* C6 *
-
2GXA
1
VE1_BPV1
A:
[5-274]
--------
T
E
K
F
D
F
G
T
M
V
Q
W
A
Y
D
H
K
Y
A
E
E
S
K
I
A
Y
E
Y
A
L
A
A
G
S
-
D
S
N
A
R
A
F
L
A
---
T
N
S
----
Q
A
K
H
V
K
D
C
A
T
M
V
R
H
Y
-------
L
R
A
E
T
Q
A
L
S
----
M
P
A
--
Y
--
I
K
A
R
C
K
--
L
A
T
G
E
G
S
W
K
S
-------
I
--
L
--
T
F
F
N
Y
Q
--
N
I
E
-----
L
----
I
T
F
I
N
A
L
K
L
W
L
--
K
G
I
PK
K
N
--
C
L
A
F
I
G
P
P
NTG
K
S
M
L
C
N
S
L
I
--
H
F
L
G
-----
G
S
V
L
S
F
A
N
H
K
S
-
H
F
W
L
A
S
L
A
D
T
R
A
A
L
V
D
D
A
T
----------
H
A
---
C
W
R
Y
F
D
T
Y
L
R
N
A
L
---
D
G
Y
P
V
S
I
D
R
-----------------------
K
H
K
A
A
V
Q
I
--------
K
A
P
P
L
L
V
T
S
N
I
D
V
Q
A
E
D
R
Y
L
Y
L
H
S
R
V
Q
T
F
R
F
----
E
Q
P
C
T
D
E
S
G
E
Q
P
F
N
I
-------------------------------
T
D
A
D
W
K
S
F
F
V
R
L
W
G
R
L
D
L
-------
22
Fugue
52.39
15%
25
- C4 -
-
5MQF
-
CDC5L_HUMAN
L:
[10-795]
------
V
W
R
N
T
E
D
E
I
L
K
A
A
V
M
K
Y
G
K
N
Q
W
S
R
--
I
A
S
L
L
H
R
K
S
A
-
K
Q
C
K
A
R
W
Y
E
WLD
P
S
I
K
K
T
E
W
S
R
E
E
E
E
K
L
L
H
L
A
K
L
MPTQWRT
I
A
P
I
I
G
R
T
A
----
A
Q
C
--
L
EH
Y
E
F
L
L
D
--
K
A
A
Q
R
D
D
M
D
E
-------
D
--
E
--
L
E
M
L
S
E
A
R
A
R
L
ANTQG
K
----
K
A
K
R
K
A
R
E
K
Q
L
--
E
E
A
--
R
R
--
L
A
A
L
Q
K
R
-----
R
E
L
R
A
A
G
I
--
E
I
Q
K
-----
K
R
----
K
R
K
R
G
V
D
-
Y
N
A
E
I
P
F
E
K
K
P
A
L
G
F
Y
D
T
S
E
E
N
Y
Q
A
L
D
A
D
---
F
R
K
L
R
Q
Q
D
L
D
G
E
L
---
R
S
E
K
E
G
R
D
R
K
K
D
K
Q
--
H
L
K
R
K
K
E
S
D
L
R
L
E
-
I
N
R
G
H
M
T
T
E
A
K
--
R
A
A
K
M
E
K
K
M
K
I
L
L
G
G
Y
---
Q
S
R
A
M
G
L
M
K
Q
L
N
D
L
W
D
Q
---
I
E
Q
A
H
L
E
L
R
T
F
E
E
L
K
K
H
-------------
E
D
S
A
I
P
R
R
L
E
C
L
K
E
D
V
Q
R
Q
Q
E
R
E
K
E
L
Q
H
R
Y
A
D
L
L
L
E
K
-----
16
HHSearch
40.59
20%
-159
- C5 -
-
4QIW
-
RPOP_THEKO
W:
[23-37]
------------------------
R
E
V
R
C
P
Y
C
G
S
K
I
L
Y
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
37.18
29%
-227
- C5 -
-
5FMF
-
RPAB4_YEAST
L:
[43-63]
-----------------------
T
D
A
V
R
C
K
D
C
G
H
R
I
L
L
K
A
R
T
-
K
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
35.48
19%
-135
- C4 -
-
3OT2
3
?
B:
[108-144]
----------------------------------------------------------------------------------------------------------------------------------------
W
T
I
E
I
L
S
P
D
Q
S
-----
Q
----
T
K
V
T
K
N
I
L
H
C
L
--
K
H
G
--
T
Q
--
M
G
W
L
I
D
P
-----
D
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
34.69
18%
-208
- C5 -
-
4AYB
-
?
P:
[21-37]
-----------------------
L
P
G
V
R
C
P
Y
C
G
Y
K
I
I
F
M
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
33.91
18%
-48
- C4 -
-
3DNX
-
?
A:
[8-88]
-----------------------------------------------------------------
L
D
L
Q
P
G
Q
R
L
A
R
G
-------
V
A
R
H
L
R
A
H
G
----
F
V
S
--
V
--
E
E
F
V
P
A
--
R
-
G
L
R
V
D
V
M
G
L
------
G
PK
G
E
I
W
V
I
E
C
K
S
S
R
A
D
-----
F
----
Q
A
-
D
A
K
W
Q
G
Y
L
--
E
-
W
--
C
D
--
R
Y
F
W
A
V
D
-----
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
32.48
13%
-83
- C5 -
-
5K2M
-
?
F:
[20-34]
------------------------
Q
I
V
E
C
P
V
C
G
A
E
L
E
V
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
32.16
18%
-167
- C5 -
-
2Y0S
-
?
P:
[21-37]
-----------------------
L
P
G
V
R
C
P
Y
C
G
Y
K
I
I
F
M
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
29.54
19%
-79
- C5 -
-
3WWL
-
LYSW_THET8
A:
[20-35]
-----------------------
G
E
L
V
V
C
E
D
C
G
A
E
L
E
V
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
29.52
16%
-53
- C4 -
-
3IJM
-
?
B:
[28-120]
---------------------------------------------------------------------
I
H
Q
S
V
I
A
R
-------
L
T
A
G
L
Y
P
L
Y
Q
S
KK
I
P
F
E
P
L
--
P
E
T
M
L
T
EG
Y
S
S
P
V
P
D
V
L
L
Y
DHQTEE
A
--
K
--
V
I
I
E
V
C
Q
N
S
G
L
-----
K
----
H
D
T
S
K
I
V
K
L
I
E
D
N
A
Y
G
--
I
L
--
E
G
F
V
F
N
Y
-----
K
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
28.99
16%
-54
- C4 -
-
3IJM
2
?
A:
[28-120]
---------------------------------------------------------------------
I
H
Q
S
V
I
A
R
-------
L
T
A
G
L
Y
P
L
Y
Q
S
KK
I
P
F
E
P
L
--
P
E
T
M
L
T
EG
Y
S
S
P
V
P
D
V
L
L
Y
DHQTEE
A
--
K
--
V
I
I
E
V
C
Q
N
S
G
L
-----
K
----
H
D
T
S
K
I
V
K
L
I
E
DN
A
Y
G
--
I
L
--
E
G
F
V
F
N
Y
-----
K
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
28.66
19%
-58
- C5 -
-
3WWN
-
?
B:
[20-35]
-----------------------
G
E
L
V
V
C
E
D
C
G
A
E
L
E
V
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
26.04
13%
-26
- C5 -
-
5K2M
-
?
E:
[20-34]
------------------------
Q
I
V
E
C
P
V
C
G
A
E
L
E
V
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
25.61
24%
17
* C4 *
-
5A31
-
CDC26_HUMAN
G:
[1-25]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
R
R
K
P
---
T
R
L
E
L
K
L
D
D
I
E
E
F
E
--
N
I
R
K
D
-------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
25.57
24%
17
- C4 -
-
4UI9
-
CDC26_HUMAN
G:
[1-25]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
R
R
K
P
---
T
R
L
E
L
K
L
E
D
I
E
E
F
E
--
N
I
R
K
D
-------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
25.57
24%
17
- C4 -
-
5LCW
-
CDC26_HUMAN
G:
[1-25]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
R
R
K
P
---
T
R
L
E
L
K
L
D
D
I
E
E
F
E
--
N
I
R
K
D
-------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
22.74
27%
32
- C5 -
-
5FLM
-
RPAB4_BOVIN
L:
[15-29]
------------------------
M
I
Y
I
C
G
E
C
H
T
E
N
E
I
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------