@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y130: (2018-01-23 )
MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGKMIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPTHVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLNGIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGFLGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS
Atome Classification :
(16 SA)
---------------------.........10........20........30.......-.40.-------------........50.---------.....----.-.60...-....---.70......--.--.--80..---...------....90........100.-.....------..110..-.....-120...-....130..----....--.-..140.......----150.......160.......170.......180..-..--...190--.------------------------........200.-......210----------...-------....220.-------------------------.---------------------------------.....230.......240--.........250....--------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------MF
N
L
Y
F
T
A
L
K
S
L
A
I
K
E
T
N
R
Y
L
R
I
W
V
Q
T
LV
P
P
V
I
T
T
S
L
Y
-
F
V
-
I
-------------
F
G
K
M
IGGRIGD---------MG
G
F
S
----
Y
-
M
E
F
I
V
P
-
G
L
I
M
---
M
S
A
I
T
S
S
Y
A
--
N
--
V
--
S
-
S
S
---
F
F
S
------
Q
K
F
Q
K
N
I
E
E
I
LVAPV-P
T
-
H
V
I
I
W
------
G
F
V
I
GGV-
G
R
S
I
L
-
V
G
S
L
V
T
-
I
I
S
L
F
--
F
V
----
P
L
H
V
--
Y
-
S
W
F
M
V
I
I
T
L
L
M
T
----
A
I
L
F
S
L
A
G
L
L
N
G
I
F
AQSYDD
V
S
I
V
P
T
F
V
L
Q
P
L
T
Y
L
-
G
G
--
V
F
Y
A
----
I
------------------------
S
ML
P
P
F
W
Q
A
V
S
K-VN
P
I
V
Y
M
IS----------GFR-------YG
F
L
G
T
ID-------------------------V---------------------------------
P
V
A
T
S
M
I
V
L
V
L
F
I
V
V
L
----
Y
A
V
T
W
Y
LINKGRGLRS--------
4
HHSearch
75.92
12%
-145
- C3 -
-
5NJ3
1
?
A:
[380-664]
-----------------------
T
S
F
C
H
Q
L
R
W
V
S
K
R
S
F
K
N
L
L
G
N
P
Q
-
A
S
I
A
Q
I
I
V
T
V
V
L
-
G
L
-
V
-------------
I
G
A
I
Y
F
G
L
K
N
D
------------
S
T
------
G
I
Q
N
R
A
-
G
V
L
F
---
F
L
T
T
N
Q
C
F
S
--
S
--
V
--
S
-
A
V
---
E
L
F
------
V
V
E
K
K
L
F
I
H
E
Y
I
S
G
Y
-
Y
R
V
S
S
Y
F
L
------
G
K
L
L
S
D
L
L
P
M
R
M
L
-
P
S
I
I
F
T
-
C
I
V
Y
F
--
M
L
----
G
L
K
P
K
A
D
-
A
F
F
V
M
M
F
T
L
M
M
V
----
A
Y
S
A
S
S
M
A
L
A
I
A
A
G
Q
S
V
V
S
V
A
T
L
L
M
T
I
C
F
V
F
M
M
I
F
-
S
G
--
L
L
V
N
----
L
------------------------
T
T
I
A
S
W
L
S
W
L
Q
Y
-
F
S
I
P
R
Y
G
F
T
----------
A
L
Q
-------
H
N
E
F
L
G
Q
N
-------------------------
F
CPGLNATGNNPCNYATCT
G
E
E
Y
L
V
K
Q
GIDLS
P
W
G
L
W
K
N
H
V
A
L
A
C
M
I
V
I
F
----
L
T
I
A
Y
L
K
L
L
F
L
K
K
Y
S
---------
3
HHSearch
75.58
12%
-145
- C3 -
-
5NJG
1
?
B:
[380-664]
-----------------------
T
S
F
C
H
Q
L
R
W
V
S
K
R
S
F
K
N
L
L
G
N
P
Q
-
A
S
I
A
Q
I
I
V
T
V
V
L
-
G
L
-
V
-------------
I
G
A
I
Y
F
G
L
K
N
D
------------
S
T
------
G
I
Q
N
R
A
-
G
V
L
F
---
F
L
T
T
N
Q
C
F
S
--
S
--
V
--
S
-
A
V
---
E
L
F
------
V
V
E
K
K
L
F
I
H
E
Y
I
S
G
Y
-
Y
R
V
S
S
Y
F
L
------
G
K
L
L
S
D
L
L
P
M
R
M
L
-
P
S
I
I
F
T
-
C
I
V
Y
F
--
M
L
----
G
L
K
P
KA
D
-
A
F
F
V
M
M
F
T
L
M
M
V
----
A
Y
S
A
S
S
M
A
L
A
I
A
A
G
Q
S
V
V
S
V
A
T
L
L
M
T
I
C
F
V
F
M
M
I
F
-
S
G
--
L
L
V
N
----
L
------------------------
T
T
I
A
S
W
L
S
W
L
Q
Y
-
F
S
I
P
R
Y
G
F
T
----------
A
L
Q
-------
H
N
E
F
L
G
Q
N
-------------------------
F
CPGLNATGNNPCNYATCTGEEYLVKQGIDLSPW
G
L
W
K
N
H
V
A
L
A
C
M
I
V
I
F
----
L
T
I
A
Y
L
K
L
L
F
L
K
K
Y
S
---------
8
HHSearch
70.44
10%
-163
- C3 -
-
5DO7
-
ABCG8_HUMAN
D:
[395-671]
-----------------------
P
G
A
V
Q
Q
F
T
T
L
I
R
R
Q
I
S
N
D
F
R
D
L
P
-
T
L
L
I
H
G
A
E
A
C
L
M
-
S
M
-
T
-------------
I
G
F
L
Y
F
G
H
G
S
I
-------------
Q
----
L
-
S
F
M
D
T
A
-
A
L
L
F
---
M
I
G
A
L
I
P
F
N
--
V
--
I
--
L
D
V
I
---
S
K
C
------
Y
S
E
R
A
M
L
Y
Y
E
L
E
D
G
L
Y
T
T
-
G
P
Y
F
F
------
A
K
I
L
G
E
L
-
P
E
H
C
A
-
Y
I
I
I
Y
G
-
M
P
T
Y
W
--
L
A
----
N
L
R
P
GL
Q
-
P
F
L
L
H
F
L
L
V
W
L
V
----
V
F
C
C
R
I
M
A
L
A
A
A
A
L
L
P
T
F
H
M
A
S
F
F
S
N
A
L
Y
N
S
F
Y
L
A
-
G
G
--
F
M
I
N
----
L
------------------------
S
S
L
W
T
V
P
A
W
I
S
K
-
V
S
F
L
R
W
C
F
E
----------
G
L
M
-------
K
I
Q
F
S
R
R
T
Y
K
M
P
L
GNL
T
I
A
V
S
GD
K
I
L
S
V
M
ELDS
Y
---------------------------------
P
L
Y
A
I
Y
L
I
V
I
G
L
S
G
G
F
----
M
V
L
Y
Y
V
S
L
R
F
I
K
Q
K
P
---------
6
HHSearch
66.20
11%
-152
- C3 -
-
5DO7
-
ABCG5_HUMAN
A:
[362-649]
-----------------------
P
G
V
F
S
K
L
G
V
L
L
R
R
V
T
R
N
L
V
R
N
K
L
-
A
V
I
T
R
L
L
Q
N
L
I
M
-
G
L
-
F
-------------
L
L
F
F
V
L
R
V
R
S
N
-----------
V
L
K
----
G
-
A
I
Q
D
R
V
-
G
L
L
Y
Q
F
V
G
A
T
P
Y
T
G
M
---
L
--
N
--
A
-
V
N
---
L
F
P
------
V
L
R
A
V
S
D
Q
E
S
Q
D
G
L
Y
-
Q
K
-
W
Q
M
M
L
------
A
Y
A
L
H
V
L
-
P
F
S
V
V
-
A
T
M
I
F
S
-
S
V
C
Y
W
--
T
L
----
G
L
H
P
E
V
A
-
R
F
G
Y
F
S
A
A
L
L
A
P
----
H
L
I
G
E
F
L
T
L
V
L
L
G
I
V
Q
N
P
N
I
V
N
S
V
V
A
L
L
S
I
A
G
V
L
V
G
S
G
--
F
L
R
N
----
I
------------------------
Q
E
M
P
I
P
F
K
I
I
S
Y
-
F
T
F
Q
K
Y
C
S
E
----------
I
L
V
-------
V
N
E
F
Y
G
L
N
-------------------------
F
T
CAFTQ
G
I
Q
F
I
E
K
TCPGATS-------------
R
F
T
M
N
F
L
I
L
Y
S
F
I
P
A
L
----
V
I
L
G
I
V
V
F
K
I
R
D
H
L
I
---------
5
HHSearch
63.66
11%
-142
- C3 -
-
5DO7
-
ABCG5_HUMAN
C:
[362-649]
-----------------------
P
G
V
F
S
K
L
G
V
L
L
R
R
V
T
R
N
L
V
R
N
K
L
-
A
V
I
T
R
L
L
Q
N
L
I
M
-
G
L
-
F
-------------
L
L
F
F
V
L
R
V
R
S
N
-----------
V
L
K
----
G
-
A
I
Q
D
R
V
-
G
L
L
Y
Q
F
V
G
A
T
P
Y
T
G
M
---
L
--
N
--
A
-
V
N
---
L
F
P
------
V
L
R
A
V
S
D
Q
E
S
Q
D
G
L
Y
-
Q
K
-
W
Q
M
M
L
------
A
Y
A
L
H
V
L
-
P
F
S
V
V
-
A
T
M
I
F
S
-
S
V
C
Y
W
--
T
L
----
G
L
H
P
E
V
A
-
R
F
G
Y
F
S
A
A
L
L
A
P
----
H
L
I
G
E
F
L
T
L
V
L
L
G
I
V
Q
N
P
N
I
V
N
S
V
V
A
L
L
S
I
A
G
V
L
V
G
S
G
--
F
L
R
N
----
I
------------------------
Q
E
M
P
I
P
F
K
I
I
S
Y
-
F
T
F
Q
K
Y
C
S
E
----------
I
L
V
-------
V
N
E
F
Y
G
L
N
-------------------------
F
TCGSMCAFTQ
G
I
Q
F
I
E
K
TCPGATS---------
R
F
T
M
N
F
L
I
L
Y
S
F
I
P
A
L
----
V
I
L
G
I
V
V
F
K
I
R
D
H
L
I
---------
19
Fugue
58.46
13%
-94
- C1 -
-
5CR9
3
?
A:
[15-309]
-------------------------------
H
F
P
L
T
I
T
N
C
G
V
D
V
T
F
D
G
P
P
E
R
I
I
L
L
E
S
A
-
P
V
A
T
M
------------
R
A
L
G
V
L
D
S
V
V
L
---------
R
A
G
A
F
----
P
-
P
E
Y
Y
D
A
-
E
T
N
A
---
A
L
R
A
I
P
S
L
G
--
E
--
E
--
L
-
D
S
-----
S
------
G
H
L
Q
I
S
E
E
V
I
I
A
Q
Q
P
-
D
----
L
V
L
------
G
L
P
D
G
V
T
-
R
E
G
L
E
-
A
V
G
I
N
V
-
L
V
Q
P
T
M-
C
P
GGVG
A
T
T
F
--
D
-
D
V
Y
E
Q
I
N
T
Y
G
R
L
F
DR
Q
D
R
A
A
E
L
V
A
S
L
R
Q
R
V
A
A
V
E
K
A
V
E
K
R
R
S
A
A
V
L
Y
P
T
I
G
-
G
G
--
V
G
Y
A
----
Y
G
NESM
A
H
P
Q
L
E
S
A
GFTNVYADVDE
R
V
F
E
V
T
L
E
D
V
L
E
-
Q
D
P
D
V
L
V
L
L
H
VDGD
P
D
A
V
K
D
A
V
-------
V
N
L
P
G
A
D
A
-------------------------
L
---------------------------------
T
A
V
R
N
D
D
I
L
V
Q
L
F
N
F
T
EPPT
P
L
S
V
D
G
L
E
R
I
H
E
T
F
G
A
--------
9
HHSearch
57.10
11%
-199
- C3 -
-
5XJY
-
?
A:
[656-1118]
----------------------------------------------------------------------------------------------------------
V
-
M
S
R
S
M
P
-
L
F
M
T
---
L
A
W
I
Y
S
-
V
A
--
V
--
I
--
I
-
K
G
---
I
V
Y
------
E
K
E
A
R
L
K
E
T
M
R
I
M
G
L
-
D
N
-
S
I
L
W
F
------
S
W
F
I
S
S
--
L
I
P
L
L
-
V
S
A
G
L
L
-
V
V
I
L
K
--
L
G
----
N
L
L
P
--
Y
S
D
P
S
V
V
F
V
F
L
S
V
F
----
A
V
V
T
I
L
Q
C
F
L
I
S
T
L
F
S
R
A
N
L
A
A
A
C
G
G
I
I
Y
F
T
L
Y
L
P
-
Y
V
L
-
C
V
A
W
----
Q
------------------------
D
Y
V
G
F
T
L
K
I
F
A
S
L
L
S
P
V
A
F
G
F
G
----------
C
E
Y
F
A
L
F
EEQ---------------------------------------------------------------------
G
F
N
L
T
T
S
V
S
M
M
L
F
D
----
T
F
L
Y
G
V
M
T
W
Y
I
E
A
V
----------
15
Fugue
56.79
14%
-55
- C3 -
-
5KDR
1
ACCA_STAA8
A:
[15-327]
LDFE
K
P
L
F
E
I
R
N
K
I
E
SQ
E
E
I
D
M
L
E
A
S
L
E
R
E
T
K
K
I
Y
T
N
L
K
P
W
D
R
V
Q
I
A
R
L
Q
E
R
P
T
T
L
D
Y
I
-
P
Y
-
I
-------------
F
D
S
F
M
E
L
H
-
G
D
R
N
F
R
D
D
PA
M
I
G
G
I
G
----
F
-
L
N
G
R
A
V
-
T
V
I
G
---
Q
Q
R
G
K
D
T
K
D
--
N
--
I
--
Y
-
R
N
---
F
G
M
AH
P
E
G
Y
R
K
A
L
R
L
M
K
Q
A
E
K
F
N
R
-
P
I
-
F
T
F
I
D
T
KGAYP
G
K
A
A
E
E
R
-
G
Q
S
E
S
-
I
A
T
N
L
I
-
E
M
A
S
L
--
K
V
----
P
--------
V
I
A
I
V
I
G
E
G
G
S
----
G
G
A
L
G
I
-
G
I
A
N
K
V
L
M
L
E
N
S
T
Y
S
V
I
S
P
E
G
A
A
A
L
L
W
K
-
D
S
NL
A
K
I
A
----
A
------------------------
E
T
M
K
I
T
A
H
D
I
K
Q
-
L
G
I
I
D
D
V
I
S
----------
E
P
L
-------
G
G
A
H
K
D
I
E
-------------------------
Q
---------------------------------
Q
A
L
A
I
K
S
A
F
V
A
Q
L
D
S
L
----
E
S
L
S
R
D
E
I
A
N
D
R
F
E
K
F
R
N
I
G
S
Y
I
E
17
Fugue
44.48
24%
-145
* C2 *
-
2NVJ
-
A:
[1-25]
----------------------------
E
F
C
L
N
C
V
S
H
T
A
S
Y
L
R
L
W
A
L
S
L
A
H
A
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
42.93
18%
-35
- C3 -
-
3CWX
-
?
A:
[47-176]
-----------------------------------------------
E
V
N
P
D
I
I
K
D
E
V
F
D
F
V
-
I
-------------
V
N
R
V
L
K
-
K
I
K
D
---------
L
K
H
Y
D
----
P
M
I
E
K
I
F
E
M
G
L
N
V
---
E
I
Q
I
N
P
E
V
K
--
D
F
F
T
--
F
-
K
S
---
I
S
T
------
T
N
K
Q
R
C
F
L
S
L
------------------------
R
G
E
-
T
R
E
I
L
C
D
N
K
L
Y
N
M
L
L
A
V
F
N
S
Y
D
----
P
N
D
L
--
L
-
K
H
I
S
T
V
E
S
L
K
K
I
----
F
Y
T
I
T
C
E
A
V
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
28.28
8%
0
- C- -
-
5XJY
1
?
A:
[1598-1916]
------------------------
L
G
R
F
M
T
G
L
D
T
K
N
N
V
K
V
W
F
N
N
K
G
-
W
H
A
I
S
S
F
L
N
V
I
N
-
N
A
-
I
L
R
A
NLQKGENPSH
Y
G
I
T
A
F
N
H
P
L
N
---------
L
T
K
Q
Q
L
S
E
V
A
-
L
M
T
T
S
V
-
D
V
L
V
---
S
I
C
V
I
F
A
M
S
F
V
P
--
A
S
F
V
-
V
F
---
L
I
Q
------
E
R
V
S
K
A
K
H
L
Q
F
I
S
G
V
-
K
P
-
V
I
Y
W
L
------
S
N
F
V
W
D
M
C
N
Y
V
V
P
-
A
T
L
V
I
I
-
I
F
I
C
F
--
Q
Q
----
K
S
Y
V
SS
T
-
N
L
P
V
L
A
L
L
L
L
L
Y
----
G
W
S
I
T
P
L
M
Y
P
A
S
F
V
F
K
I
P
S
T
A
Y
V
V
L
T
S
V
N
L
F
I
G
I
N
-
G
S
--
V
A
T
F
VLEL-------------------------
N
N
I
N
D
I
L
K
S
V
F
L
-
I
F
P
H
F
C
L
G
R
----------
G
L
I
-------
D
M
-------------------------------------------------------------------------------------------------------------
13
Fugue
27.89
24%
-35
- C3 -
-
2JTW
-
A:
[1-25]
---------------------------------
K
K
S
H
T
A
S
Y
L
R
L
W
A
L
S
L
A
H
A
Q
L
S
S
K
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
27.35
38%
8
- C2 -
-
3AWK
-
?
A:
[345-385]
-----------------------------------------------------------------------------------------------------------------------------
V
L
A
S
Y
G
--
N
--
M
--
S
-
S
A
S
V
L
F
V
L
------
D
Q
I
R
K
N
S
E
E
L
H
L
-
P
T
-
T
G
-
E
G
F
E
W
------
G
F
V
I
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
27.31
24%
-110
* C3 *
-
2RPW
-
X:
[1-25]
---------------------------------
K
K
S
H
T
A
S
Y
L
R
L
W
A
L
S
L
A
H
A
Q
L
S
S
K
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
25.14
38%
18
- C2 -
-
3AWJ
-
?
A:
[345-385]
-----------------------------------------------------------------------------------------------------------------------------
V
L
A
S
Y
G
--
N
--
M
--
S
-
S
A
S
V
L
F
V
L
------
D
Q
I
R
K
N
S
E
E
L
H
L
-
P
T
-
T
G
-
E
G
F
E
W
------
G
F
V
I
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
16.45
12%
-125
- C3 -
-
2LX0
-
?
A:
[15-31]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
T
F
----
L
A
F
G
F
W
L
F
K
Y
L
Q
K
-----------