@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y1A8: (2018-01-24 )
MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFALRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGYVDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNSWLFSFVMNGASGLSTAIVTIIVLLGIQQTTPSIFVPDKRQEL
Atome Classification :
(20 SA)
.........10........20.......-.-30........40........50........60........70........80........90........100.......110.-....---..120.......130.......140.......150.......160.......170.......180.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MGK
N
R
V
W
V
E
G
T
I
V
A
A
L
A
M
V
L
S
L
I
P
IQIG-S-S
F
S
I
SLGQI
P
L
T
L
F
A
L
RRGTK
A
G
M
L
A
G
F
I
W
G
I
L
H
FPL
G
Q
V
Y
Y
L
S
V
V
Q
V
L
I
EYPI
A
Y
T
FAG
A
A
G
L
M
A
S
NVQKGYVDD
N
T
K
Q
I
R
K
S
-
I
V
F
G
---
A
L
I
G
A
L
S
R
Y
F
W
H
F
I
A
G
V
V
F
W
G
A
Y
A
L
W
G
M
N
S
W
L
F
S
F
V
M
NGAS
G
L
S
T
A
I
V
T
I
I
V
L
LGIQQTTP
S
I
FVPDKRQEL
44
HHSearch
93.17
44%
-171
- C6 -
-
4TKR
11
?
B:
[32-212]
-
K
R
L
I
I
L
L
E
C
A
I
F
A
A
V
A
M
V
L
S
F
I
P
L
D
I
G
-
S
-
S
F
S
I
S
L
G
M
I
P
M
Y
V
I
A
I
R
R
G
F
W
A
A
G
F
A
G
L
L
W
G
L
L
H
F
L
T
G
K
A
Y
I
L
M
P
S
Q
A
I
I
E
Y
I
L
A
F
S
F
I
A
F
S
G
V
F
S
K
Q
V
R
S
N
L
A
A
N
Q
L
K
K
A
I
E
W
-
A
W
G
T
---
M
I
I
G
G
V
A
R
Y
F
W
H
Y
V
A
G
V
L
F
W
G
A
Y
A
F
Q
G
W
G
A
Q
L
F
S
I
V
M
N
G
A
S
C
L
G
T
V
L
V
S
G
I
I
I
S
I
L
L
K
T
S
P
K
L
F
L
-------
1
PsiBlast_PDB
86.17
46%
-165
- C6 -
-
4TKR
7
?
A:
[38-213]
-------
L
E
C
A
I
F
A
A
V
A
M
V
L
S
F
I
P
L
D
I
G
-
S
-
S
F
S
I
S
L
G
M
I
P
M
Y
V
I
A
I
R
R
G
F
W
A
A
G
F
A
G
L
L
W
G
L
L
H
F
L
T
G
K
A
Y
I
L
M
P
S
Q
A
I
I
E
Y
I
L
A
F
S
F
I
A
F
S
G
V
F
S
K
Q
V
R
S
---
N
L
A
A
N
Q
L
K
K
A
-
I
E
W
A
W
G
T
M
I
I
G
G
V
A
R
Y
F
W
H
Y
V
A
G
V
L
F
W
G
A
Y
A
F
Q
G
W
G
A
Q
L
F
S
I
V
M
N
G
A
S
C
L
G
T
V
L
V
S
G
I
I
I
S
I
L
L
K
T
S
P
K
L
F
L
P
------
21
PsiBlast_CBE
86.09
46%
-165
- C6 -
-
4TKR
11
?
B:
[38-213]
-------
L
E
C
A
I
F
A
A
V
A
M
V
L
S
F
I
P
L
D
I
G
-
S
-
S
F
S
I
S
L
G
M
I
P
M
Y
V
I
A
I
R
R
G
F
W
A
A
G
F
A
G
L
L
W
G
L
L
H
F
L
T
G
K
A
Y
I
L
M
P
S
Q
A
I
I
E
Y
I
L
A
F
S
F
I
A
F
S
G
V
F
S
K
Q
V
R
S
---
N
L
A
A
N
Q
L
K
K
A
-
I
E
W
A
W
G
T
M
I
I
G
G
V
A
R
Y
F
W
H
Y
V
A
G
V
L
F
W
G
A
Y
A
F
Q
G
W
G
A
Q
L
F
S
I
V
M
N
G
A
S
C
L
G
T
V
L
V
S
G
I
I
I
S
I
L
L
K
T
S
P
K
L
F
L
P
------
34
Fugue
81.66
35%
-176
- C6 -
-
3RLB
8
?
A:
[17-192]
--
N
V
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
R
Q
K
--------
T
A
P
L
K
L
A
P
-
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
Y
---
46
HHSearch
79.24
36%
-192
- C6 -
-
3RLB
8
?
A:
[17-189]
--
N
V
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
-
T
V
Y
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
R
Q
K
T
A
P
---
L
-----
K
L
A
P
-
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
------
2
PsiBlast_PDB
78.58
34%
-181
- C6 -
-
3RLB
8
?
A:
[19-191]
----
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
---------
R
Q
K
T
A
P
L
K
L
A
P
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
----
45
HHSearch
77.55
36%
-194
* C6 *
-
4MES
16
?
B:
[6-179]
-
F
N
V
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
-
T
V
-
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
R
Q
K
T
A
P
L
--------
K
L
A
P
-
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
------
8
PsiBlast_PDB
76.95
34%
-183
- C6 -
-
4N4D
19
?
A:
[9-181]
----
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
---------
R
Q
K
T
A
P
L
K
L
A
P
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
----
23
PsiBlast_CBE
76.77
34%
-185
- C6 -
-
4POP
8
THIT_LACLM
B:
[19-191]
----
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
---------
R
Q
K
T
A
P
L
K
L
A
P
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
----
26
PsiBlast_CBE
76.63
34%
-188
- C6 -
-
3RLB
8
?
B:
[19-191]
----
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
---------
R
Q
K
T
A
P
L
K
L
A
P
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
----
22
PsiBlast_CBE
76.60
34%
-183
- C6 -
-
4POV
12
THIT_LACLM
B:
[19-191]
----
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
---------
R
Q
K
T
A
P
L
K
L
A
P
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
----
28
PsiBlast_CBE
76.46
34%
-187
- C6 -
-
4MES
16
?
B:
[9-181]
----
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
---------
R
Q
K
T
A
P
L
K
L
A
P
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
----
24
PsiBlast_CBE
76.12
34%
-182
- C6 -
-
4MUU
15
?
B:
[19-191]
----
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
---------
R
Q
K
T
A
P
L
K
L
A
P
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
----
25
PsiBlast_CBE
75.91
34%
-180
- C6 -
-
4MHW
13
?
B:
[19-191]
----
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
---------
R
Q
K
T
A
P
L
K
L
A
P
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
----
5
PsiBlast_PDB
75.83
34%
-185
- C6 -
-
4POP
29
THIT_LACLM
A:
[19-191]
----
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
---------
R
Q
K
T
A
P
L
K
L
A
P
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
----
7
PsiBlast_PDB
75.81
34%
-184
- C6 -
-
4MES
29
?
A:
[9-181]
----
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
---------
R
Q
K
T
A
P
L
K
L
A
P
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
----
3
PsiBlast_PDB
75.61
34%
-185
- C6 -
-
4MHW
21
?
A:
[19-191]
----
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
---------
R
Q
K
T
A
P
L
K
L
A
P
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
----
4
PsiBlast_PDB
75.59
34%
-186
- C6 -
-
4MUU
22
?
A:
[19-191]
----
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
---------
R
Q
K
T
A
P
L
K
L
A
P
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
----
27
PsiBlast_CBE
75.37
34%
-183
- C6 -
-
4N4D
14
?
B:
[9-181]
----
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
---------
R
Q
K
T
A
P
L
K
L
A
P
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
----
6
PsiBlast_PDB
75.12
34%
-190
- C6 -
-
4POV
25
THIT_LACLM
A:
[19-191]
----
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
-
G
-
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
---------
R
Q
K
T
A
P
L
K
L
A
P
V
L
L
G
---
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
N
----