@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y1G4: (2018-01-25 )
MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFDELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHYEKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIFSGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLSLVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLSTISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGGDIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY
Atome Classification :
(20 SA)
.........10........20........30........40......-..50........60-.........70........80........90--....-..-..100.......110.......120...------------....130..-...-----..140.......150.......160.......170.......180.......190-.......-.200........210-.......220.......230.......240.......250.......260.......270.......280.......290..----.----....300..--...-...310-.......-.320.......330.------.--.....-----------------.-----------------.-------------------------340-----------------.......350.......360.......370...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MS
L
L
T
FER
N
L
L
LKN
K
V
N
F
L
F
P
L
L
L
V
V
L
F
A
F
P
L
F
FDHKLAY
T
E
F
D
E
LN-H
N
Y
E
E
M
Q
R
L
I
E
T
L
--KEDE
N
E
K
E
F
V
E
S
L
E
KS
N
K
L
I
E
A
I
L
HAKNTG
N
--
V
Q
Q
M
-
V
E
-
A
T
Y
H
Y
E
K
D
I
L
D
R
L
ISGQRQGIP
I
I
E
Q
Q
K
------------
R
V
E
L
L
R
Y
M
K
-
E
HQ-----
I
Q
R
Y
S
I
FDLP
A
H
L
S
L
A
N
Y
Y
E
N
I
F
S
G
M
I
S
S
F
L
I
L
C
I
T
A
L
F
L
S
S
I
I
S
Y
E
K
R
K
Q
V
I
S
--
L
V
N
LL
P
D
-
S
M
-
V
KKH
S
I
R
F
T
I
Y
Y
-
G
A
A
M
L
S
L
V
M
P
F
L
I
V
S
I
L
V
I
I
KNGLGDFRY
P
V
G
T
IIGQE
I
R
I
L
P
M
Y
E
Y
L
F
Q
S
F
L
F
L
L
L
W
V
L
F
L
S
T
I
S
F
L
L
S
A
L
F
E
H
S
L
V
N
L
L
G
----
T
----
L
L
C
L
F
L
-
A
E
--
Y
R
L
-
F
S
SI-
G
-
W
I
E
S
I
S
H
-YLPTSYVDF
Q
N
V
--
I
------I--GGDIF-----------------S-----------------P-------------------------L
A
S
-----------------
E
Q
V
T
F
M
N
G
I
L
T
L
G
I
W
S
I
V
L
L
F
IGM
G
T
I
Y
I
KKSY
1
PsiBlast_PDB
67.11
33%
22
- C1 -
-
3V71
-
PUF7_CAEEL
A:
[44-145]
----------------------------------------------------------------
E
D
Q
I
R
K
A
V
F
E
K
F
T
E
S
T
T
L
F
V
G
L
C
H
S
R
N
-
G
N
F
I
V
Q
K
L
-
V
E
L
A
T
P
A
E
Q
R
E
L
L
R
Q
M
I
D
G
---
G
L
L
A
M
C
K
D
K
F
A
C
---------
R
V
V
Q
L
A
L
Q
K
F
D
H
S
N
V
F
Q
L
I
Q
E
L
S
T
F
D
L
A
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
64.04
25%
54
- C1 -
-
5J70
2
?
A:
[32-190]
-------------------------------
L
I
A
D
G
T
L
P
V
K
S
F
E
K
Y
G
-
E
T
Y
D
E
M
M
E
A
A
K
D
C
V
H
E
E
E
K
N
R
K
E
I
L
E
K
L
E
K
H
A
T
A
Y
R
A
K
L
K
S
G
E
----------
I
K
-
A
E
N
Q
P
K
D
N
P
L
T
R
L
S
L
K
K
R
E
K
K
A
V
L
F
N
F
K
GVKSLN
A
E
S
L
L
S
R
V
E
D
L
K
Y
L
K
-
N
L
I
-----
N
S
N
Y
K
--
D
D
P
L
K
F
S
L
G
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
63.46
25%
44
- C1 -
-
3TED
2
A:
[32-191]
-------------------------------
L
I
A
D
G
T
L
P
V
K
S
F
E
K
Y
G
-
E
T
Y
D
E
M
M
E
A
A
K
D
C
V
H
E
E
E
K
N
R
K
E
I
L
E
K
L
E
K
H
A
T
A
Y
R
A
K
L
K
S
G
E
----------
I
K
-
A
E
N
Q
P
K
D
N
P
L
T
R
L
S
L
K
K
R
E
K
K
A
V
L
F
N
F
K
GVKSLN
A
E
S
L
L
S
R
V
E
D
L
K
Y
L
K
-
N
L
I
-----
N
S
N
Y
K
--
D
D
P
L
K
F
S
L
G
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
62.49
16%
-
- C1 -
-
4RFX
-
DCTN1_CHICK
A:
[432-531]
-------------------------------------
M
V
E
T
L
T
E
R
N
L
-
D
L
E
E
K
V
R
E
L
R
E
T
V
--
G
D
L
E
A
M
N
E
M
N
D
E
L
Q
E
N
A
R
E
T
E
L
E
L
R
E
Q
L
D
L
A
--
A
A
R
V
-
R
E
-
A
E
K
R
V
E
A
A
Q
E
T
V
A
D
Y
Q
Q
T
I
K
K
Y
R
E
L
T
A
H
------------
L
Q
D
V
N
R
E
L
M
-
S
Q
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
60.53
25%
60
- C1 -
-
2XB0
2
X:
[31-190]
-------------------------------
L
I
A
D
G
T
L
P
V
K
S
F
E
K
Y
G
-
E
T
Y
D
E
M
M
E
A
A
K
D
C
VH
E
E
E
K
N
R
K
E
I
L
E
K
L
E
K
H
A
T
A
Y
R
A
K
L
K
S
G
E
----------
I
K
-
A
E
N
Q
P
K
D
N
P
L
T
R
L
S
L
K
K
R
E
K
K
A
V
L
F
N
F
K
GVKSLNAESLLS
R
V
E
D
L
K
Y
L
K
-
N
L
I
-----
N
S
N
Y
K
--
D
D
P
L
K
F
S
L
G
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
59.08
10%
-112
- C1 -
-
4QKW
-
CVN4A_DANRE
A:
[3-103]
--------------------------------
P
V
S
A
L
S
I
L
S
L
L
E
R
V
S
-
T
I
I
D
G
V
Q
A
S
Q
Q
R
M
--
E
E
R
Q
Q
Q
L
E
G
S
V
S
A
V
Q
S
E
L
L
K
L
A
R
D
H
G
A
T
A
T
T
--
V
D
K
L
-
L
Q
-
K
A
R
R
V
S
T
H
V
K
E
V
R
S
R
V
E
K
Q
N
V
R
V
K
K
V
E
T
------------
T
Q
D
E
L
L
T
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
58.98
17%
-17
- C1 -
-
5J73
-
?
A:
[6-80]
----------------------------------------------------
T
S
D
Y
I
I
E
Q
I
--
Q
R
D
Q
E
E
A
R
--
K
K
V
E
E
A
E
E
R
L
E
R
V
K
E
A
S
K
R
G
V
--
S
S
D
Q
-
L
L
-
D
L
I
R
E
L
A
E
I
I
E
E
L
I
R
I
I
R
R
S
N
E
A
I
K
E
L
I
------------
K
N
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
57.24
18%
-132
- C1 -
-
4OM3
2
TLE1_HUMAN
A:
[10-126]
--------------------------------------
K
F
T
I
P
E
S
L
D
-
R
I
K
E
E
F
Q
F
L
Q
A
Q
Y
--
H
S
L
K
L
E
C
E
K
L
A
S
E
K
T
E
M
Q
R
H
Y
V
M
Y
Y
E
M
S
Y
G
L
--
N
I
E
M
-------
H
K
Q
T
E
I
A
K
R
L
N
T
I
C
A
Q
V
I
P
F
L
S
Q
E
H
------------
Q
Q
Q
V
A
Q
A
V
E
-
R
A
K
-------
Q
V
T
M
A
E
L
N
A
I
I
G
Q
Q
Q
L
Q
A
Q
H
L
S
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
56.60
34%
-204
- C1 -
-
2FWR
2
?
A:
[197-264]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
D
E
V
H
H
L
P
A
E
S
Y
V
Q
-
I
A
Q
M
S
I
A
P
F
R
-
L
G
L
T
A
T
F
E
R
E
D
G
R
H
E
I
L
K
E
V
V
G
GK
V
F
E
L
F
P
D
-
S
L
-
A
G
K
H
L
A
K
Y
T
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
55.70
12%
-187
- C1 -
-
5XJY
-
?
A:
[673-1115]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
V
I
I
K
G
I
V
Y
E
K
E
A
R
L
K
E
--
T
M
R
I
M
G
L
-
D
N
-
S
I
L
W
F
S
W
F
I
S
S
--
L
I
P
L
L
V
S
A
G
L
L
V
V
I
L
K
L
G
N
L
L
P
Y
-------------
S
D
---------
P
S
V
V
F
V
F
L
S
V
F
A
V
V
T
I
L
Q
C
F
L
I
S
T
L
F
S
R
A
N
L
A
A
A
C
----
G
G
I
I
Y
F
T
L
Y
L
P
-
Y
V
L
C
V
A
W
-
Q
D
Y
V
G
F
-
T
L
K
I
F
A
S
L
L
S
P
V
A
F
G
F
G
C
E
Y
--
F
A
L
F
EEQ----------------------------------------------------------------------------------------------
G
F
N
L
T
T
S
V
S
M
M
L
F
D
T
F
L
Y
G
V
M
T
W
Y
I
---
17
HHSearch
55.51
14%
-178
- C1 -
-
5NJG
1
?
B:
[452-661]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
V
E
L
F
V
V
E
K
K
L
F
I
--
H
E
Y
I
S
G
Y
-
Y
R
V
S
S
Y
F
L
G
K
L
L
S
D
L
L
P
M
R
M
L
P
S
I
I
F
T
C
I
V
Y
----
F
M
L
G
L
K
---
P
K
A
-----
D
---------
A
F
F
V
M
M
F
T
L
M
M
V
A
Y
S
A
S
S
M
A
L
A
I
A
A
G
Q
S
V
V
S
V
A
T
L
L
----
M
TICF
V
F
M
M
I
F
-
S
G
--
L
L
V
N
L
T
T
I
A
S
-
W
L
S
W
L
Q
Y
-
F
S
I
P
R
Y
G
F
T
A
L
Q
--
H
NE----
F
--
L
G
Q
N
F
-----------------
C
-----------------
P
GLNATGNNPCNYATCTGEEYLVKQG
I
D
L
-----------------
S
P
W
G
L
W
K
N
H
V
A
L
A
C
M
I
V
I
F
L
T
I
A
Y
L
K
L
L
F
L
K
--
16
HHSearch
54.78
14%
-178
- C1 -
-
5NJ3
1
?
A:
[452-661]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
V
E
L
F
V
V
E
K
K
L
F
I
--
H
E
Y
I
S
G
Y
-
Y
R
V
S
S
Y
F
L
G
K
L
L
S
D
L
L
P
M
R
M
L
P
S
I
I
F
T
C
I
V
Y
----
F
M
L
G
L
K
---
P
K
A
-----
D
---------
A
F
F
V
M
M
F
T
L
M
M
V
A
Y
S
A
S
S
M
A
L
A
I
A
A
G
Q
S
V
V
S
V
A
T
L
L
----
M
T
I
C
F
V
F
M
M
I
F
-
S
G
--
L
L
V
N
L
T
T
I
A
S
-
W
L
S
W
L
Q
Y
-
F
S
I
P
R
Y
G
F
T
A
L
Q
--
H
N
E
----
F
--
L
G
Q
N
F
-----------------
C
-----------------
P
GLNATGNNPCNYATCT
G
E
E
Y
L
V
K
Q
G
I
D
L
-----------------
S
P
W
G
L
W
K
N
H
V
A
L
A
C
M
I
V
I
F
L
T
I
A
Y
L
K
L
L
F
L
K
--
23
Fugue
52.37
15%
-138
- C1 -
-
5B52
-
?
A:
[4-60]
--------------------------------
L
A
E
F
A
A
A
E
K
A
L
Q
E
Q
M
-
A
Q
L
E
A
L
K
K
D
A
G
L
K
--
R
E
I
E
F
E
Q
K
L
V
G
L
M
K
S
Y
D
K
S
L
R
D
I
I
A
I
L
D
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
50.34
12%
-170
- C1 -
-
5DO7
-
ABCG5_HUMAN
A:
[440-646]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
F
P
V
L
R
A
V
S
D
Q
--
E
S
Q
D
G
L
Y
-
Q
K
-
W
Q
M
M
L
A
Y
A
L
H
V
L
-
P
F
S
V
V
A
T
M
I
F
S
S
V
C
Y
W
----
T
L
G
L
H
-
P
E
---
V
-------------
A
R
F
G
Y
F
S
A
A
L
L
A
P
H
L
I
G
E
F
L
T
L
V
L
L
G
I
V
Q
N
P
N
I
V
N
S
V
----
V
A
L
L
S
I
A
G
V
L
V
G
S
G
--
F
L
R
N
I
Q
E
M
-
P
I
P
F
K
I
I
S
Y
-
F
T
F
Q
K
Y
C
S
E
I
L
V
--
V
------
N
E
F
Y
G
L
N
F
-----------------
T
-------------------------------------------
C
--AFTQ
G
I
Q
F
I
E
K
TCPG--
A
T
S
R
F
T
M
N
F
L
I
L
Y
S
F
I
P
A
L
V
I
L
G
I
V
V
F
K
I
R
D
--
25
Fugue
47.47
17%
-2
- C1 -
-
5D3A
1
KI21A_HUMAN
A:
[1-82]
-----------------------------------------
G
S
M
T
I
S
-
N
M
E
A
D
M
N
R
L
L
K
Q
R
--
E
E
L
T
K
R
R
E
K
L
S
K
-
R
R
E
K
I
V
K
E
N
G
E
G
D
K
N
V
A
N
--
I
N
E
E
-
M
E
-
S
L
T
A
N
I
D
Y
I
N
D
S
I
S
D
C
Q
A
N
I
M
Q
M
E
E
A
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
47.30
12%
-148
- C1 -
-
5DO7
-
ABCG5_HUMAN
C:
[440-646]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
F
P
V
L
R
A
V
S
D
Q
--
E
S
Q
D
G
L
Y
-
Q
K
-
W
Q
M
M
L
A
Y
A
L
H
V
L
-
P
F
S
V
V
A
T
M
I
F
S
S
V
C
Y
W
----
T
L
G
L
H
-
P
E
---
V
-------------
A
R
F
G
Y
F
S
A
A
L
L
A
P
H
L
I
G
E
F
L
T
L
V
L
L
G
I
V
Q
N
P
N
I
V
N
S
V
----
V
A
L
L
S
I
A
G
V
L
V
G
S
G
--
F
L
R
N
I
Q
E
M
-
P
I
P
F
K
I
I
S
Y
-
F
T
F
Q
K
Y
C
S
E
I
L
V
--
V
------
N
E
F
Y
G
L
N
F
-----------------
T
-------------------------------------------
C
G
S
MCAFTQ
G
I
Q
F
I
E
K
TCPG
A
T
S
R
F
T
M
N
F
L
I
L
Y
S
F
I
P
A
L
V
I
L
G
I
V
V
F
K
I
R
D
--
13
HHSearch
47.05
9%
-176
- C1 -
-
5DO7
-
ABCG8_HUMAN
D:
[472-668]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
C
Y
S
E
R
A
M
L
Y
--
Y
E
L
E
D
G
L
Y
T
T
-
G
P
Y
F
F
A
K
I
L
G
E
L
-
P
E
H
C
A
Y
I
I
I
Y
G
M
P
T
Y
W
L
A
----
N
L
R
---
P
G
L
--------------
Q
P
F
L
L
H
F
L
L
V
W
L
V
V
F
C
C
R
I
M
A
L
A
A
A
A
L
L
P
T
F
H
M
A
S
F
F
----
S
N
A
L
Y
N
S
F
Y
L
A
-
G
G
--
F
M
I
N
L
S
S
L
-
W
T
V
P
A
W
I
S
K
-
V
S
F
L
R
W
C
F
E
G
L
M
K
I
Q
------
F
--
S
R
R
T
Y
-----------------
K
M
P
L
GNL
T
I
A
V
S
GD
K
I
L
S
V
-------------------------
M
E
L
-----------------
D
S
Y
P
L
Y
A
I
Y
L
I
V
I
G
L
S
G
G
F
M
V
L
Y
Y
V
S
L
R
F
I
K
--
12
HHSearch
46.79
9%
-174
- C1 -
-
5DO7
-
ABCG8_HUMAN
B:
[473-668]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
Y
S
E
R
A
M
L
Y
--
Y
E
L
E
D
G
L
Y
T
T
-
G
P
Y
F
F
A
K
I
L
G
E
L
-
P
E
H
C
A
Y
I
I
I
Y
G
M
P
T
Y
W
L
A
----
N
L
R
---
P
G
--
L
------------
Q
P
F
L
L
H
F
L
L
V
W
L
V
V
F
C
C
R
I
M
A
L
A
A
A
A
L
L
P
T
F
H
M
A
S
F
F
S
N
A
L
Y
----
N
S
F
Y
L
A
-
G
G
--
F
M
I
N
L
S
S
L
-
W
T
V
P
A
W
I
S
K
-
V
S
F
L
R
W
C
F
E
G
L
M
--
K
I
Q
----
F
--
S
R
R
T
Y
K
M
P
L
G
NLTIAVSGD
K
I
L
S
-----------------
V
-------------------------
M
E
L
-----------------
D
S
Y
P
L
Y
A
I
Y
L
I
V
I
G
L
S
G
G
F
M
V
L
Y
Y
V
S
L
R
F
I
K
--
6
PsiBlast_PDB
46.49
33%
114
- C1 -
-
4LUG
-
IPYR1_ARATH
A:
[119-166]
---------------------------------------
Y
T
D
I
K
E
L
P
P
H
R
L
S
E
I
R
R
F
F
E
D
Y
--
K
K
N
E
N
K
E
V
A
V
N
D
F
L
P
S
E
S
A
V
E
A
I
Q
Y
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
45.38
19%
27
- C1 -
-
1UIX
-
ROCK2_BOVIN
A:
[-2-1045]
--------------------------------
T
S
D
V
A
N
L
A
N
E
K
E
E
L
N
-
N
K
L
K
E
A
Q
E
Q
L
S
R
L
--
K
D
E
E
I
S
A
A
A
I
K
A
Q
F
E
K
Q
L
L
T
E
R
T
L
K
T
Q
A
V
N
K
--
L
A
E
I
M
N
R
-
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------