@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y373: (2018-02-03 )
MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRIVYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEYTIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESSTENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMSSESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQEKAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK
Atome Classification :
(20 SA)
-----------------------------------.........10....-....20........30........-----40........50........60........70...----.....80........90..-------.....----.100----....-------------------------...110.......120--......----...130--........140.......--------150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270........280....--...290...---------....300.......310.......320..------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------------------------------MKK
T
A
T
V
L
F
V
I
L
G
L
S
-
I
I
A
A
M
IGISTSANERANE
N
L
S
F
T
V
-----KT
D
R
I
V
YDMTQ
Q
V
I
T
I
PVKPNKSVNAS
D
V
H
A
V
L
T
Y----GWDGNGSSE
K
V
I
G
E
V
Y
L
KD-------
V
Q
WTA----GI
E
Y
----
T
I
M
I
-------------------------
S
A
E
L
S
I
D
EIKSKDK----
V
D
L
I
V
F
----YDG
Q
M
---
T
I
TENLKPS
S
W
T
V
VGPPS--------STDSTSSESSTENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMSSESSTGSTSSESSTGKVNNEL
D
L
V
PIIP
T
K
E
Q
K
RNAG
S
N
L
K
S
V
LKQ
P
D
F
V
S
RG-I
D
H
Q
E
K
A
KETDNRKS--DLPET
G
S
R
T
---------
L
N
K
L
I
T
W
M
G
V
L
L
I
L
I
V
G
A
S
Y
F
R
S
L
F
H
RVK------------------------------------------------
3
HHSearch
87.99
100%
-158
- C7 -
-
5FCE
-
?
B:
[1-116]
-------------------------------------------------------------------
N
E
N
L
S
F
T
V
-----
K
T
D
R
I
V
Y
D
M
T
Q
Q
V
I
T
I
P
V
K
P
N
K
S
V
N
A
S
D
V
H
A
V
L
T
Y
----
G
W
D
G
N
G
S
S
E
K
V
I
G
E
V
Y
L
K
D
-------
V
Q
W
T
A
----
G
I
E
Y
----
T
I
M
I
-------------------------
S
A
E
L
S
I
D
E
I
K
S
K
D
K
----
V
D
L
I
V
F
----
Y
D
G
Q
M
---
T
I
T
E
N
L
K
P
S
S
W
T
V
V
G
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
87.00
97%
-158
- C7 -
-
5FCE
-
?
A:
[2-116]
--------------------------------------------------------------------
E
N
L
S
F
T
V
-----
K
T
D
R
I
V
Y
D
M
T
Q
Q
V
I
T
I
P
V
K
P
N
K
S
V
N
A
S
D
V
H
A
V
L
T
Y
----
G
W
D
G
N
G
S
S
E
K
V
I
G
E
V
Y
L
K
D
-------
V
Q
W
T
A
----
G
I
E
Y
----
T
I
M
I
-------------------------
S
A
E
L
S
I
D
E
I
K
S
K
D
K
----
V
D
L
I
V
F
----
Y
D
G
Q
M
---
T
I
T
E
N
L
K
P
S
S
W
T
V
V
G
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
41.89
23%
-280
- C7 -
-
3TLK
1
FEPB_ECOLI
A:
[104-125]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
P
S
A
E
A
V
A
A
Q
-
M
----
P
D
L
I
L
I
----
S
A
T
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
40.98
23%
-293
- C7 -
-
3TLK
1
FEPB_ECOLI
B:
[104-125]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
P
S
A
E
A
V
A
A
Q
-
M
----
P
D
L
I
L
I
----
S
A
T
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
38.80
7%
40
- C6 -
-
1DCT
4
MTH3_HAEAE
A:
[1-324]
----------------------------------------------
M
N
L
I
-
S
L
F
S
G
A
G
G
L
D
L
G
F
Q
K
A
G
F
R
I
I
C
A
N
E
YDKS
I
W
K
T
Y
E
S
N
H
S
A
K
L
I
K
G
D
I
S
K
I
S
S
D
E
F
P
K
C
D
G
I
I
G
G
P
PCQ
S
W
S
E
G
G
S
L
R
G
I
D
D
P
R
G
K
L
F
-------
Y
E
Y
I
R
----
I
L
K
Q
K
KPI
F
F
L
A
-------------------------
E
N
V
K
G
M
M
A
Q
R
H
N
K
A
----
V
Q
E
F
I
Q
----
E
F
D
N
A
---
G
Y
D
V
H
I
I
L
L
N
A
N
D
Y
G
V
A
Q
D
R
K
R
V
F
Y
I
G
F
R
K
E
L
N
I
-
N
Y
L
P
P
I
P
H
L
I
K
P
T
F
K
D
V
I
--
W
D
L
K
D
N
P
I
P
A
L
D
K
N
K
T
N
G
N
K
C
I
Y
P
N
H
E
Y
F
I
G
S
Y
S
T
I
F
M
S
R
N
R
V
R
Q
W
N
E
P
A
F
T
V
Q
A
S
----
G
R
Q
C
Q
L
H
P
Q
A
P
V
M
L
K
V
S
K
N
L
N
K
F
V
E
G
K
E
H
L
Y
R
R
-
L
T
V
R
E
C
A
R
V
Q
G
F
P
D
D
F
I
F
H
Y
E
S
L
N
D
G
---------
Y
K
M
I
G
N
A
V
P
V
N
L
A
Y
E
I
A
K
T
I
K
S
A
L
-----------------------------------------------------
16
HHSearch
35.99
14%
5
- C7 -
-
4PAG
2
?
A:
[4-120]
-----------------------------------------------------------------------------------
R
T
F
L
D
V
S
N
K
P
I
V
L
P
E
H
I
T
R
I
Y
G
S
A
P
P
I
S
F
M
I
Y
----
V
I
-
D
-
D
--
T
P
L
I
G
V
N
S
P
Q
T
NKDNNNG
E
K
F
L
S
K
H
F
M
E
L
P
I
----
L
G
G
W
HG-----------------------
N
N
I
P
N
L
E
A
I
L
A
A
-
K
----
P
D
V
I
I
T
----
W
D
T
P
L
L
N
E
K
T
A
K
D
L
A
R
I
S
I
P
A
L
K
V
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
35.41
15%
155
- C6 -
-
1R5S
-
A:
[1-132]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
L
G
S
P
S
K
D
C
G
S
P
K
Y
--------
A
Y
F
N
G
C
S
S
P
T
A
P
L
--
S
P
M
S
P
P
G
Y
K
L
V
T
G
D
R
N
N
S
S
C
R
N
Y
N
K
Q
A
S
E
Q
N
W
A
N
Y
S
A
E
Q
N
R
M
G
Q
A
G
S
T
I
S
N
S
H
A
Q
P
F
D
F
P
D
D
N
Q
N
A
K
K
V
A
A
G
H
E
L
Q
--
P
L
A
I
V
D
Q
R
P
S
S
R
A
S
S
R
A
S
S
R
P
R
P
D
D
L
E
I
------------------------------------------------------------------------------------------------------------------
19
HHSearch
33.87
33%
-154
- C7 -
-
2L69
-
?
A:
[56-95]
-------------------------------------------------------------------------------------------------------------------------------------
V
V
V
D
D
-------
K
E
W
--------------------------------------------
A
E
K
A
I
R
F
V
K
S
L
G
A
----
Q
V
L
I
I
I
----
Y
D
Q
D
Q
---
N
R
L
E
E
F
S
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
33.58
7%
17
- C6 -
-
2RH1
10
ADRB2_HUMAN (first)
A:
[36-477]
D
E
V
W
V
V
G
M
G
I
V
M
S
L
I
V
L
A
I
V
F
G
N
V
L
V
I
T
A
I
A
K
FER
L
Q
T
V
T
N
Y
F
I
T
S
L
A
C
A
D
L
V
M
G
L
A
V
V
P
F
G
A
A
H
I
L
M
K
M
W
T
F
G
N
-----
F
W
C
E
F
W
T
S
I
D
V
L
C
V
T
A
S
I
E
T
L
C
V
I
A
V
D
R
Y
F
A
I
T
S
P
----
F
K
Y
Q
S
L
L
T
K
N
K
A
R
V
I
I
L
M
V
-------
W
I
V
S
G
----
L
T
S
F
----
L
P
I
Q
M
HWYRATH
Q
E
A
I
N
C
Y
A
EETCCDFFT
N
Q
A
Y
A
I
A
S
S
I
V
S
F
Y
----
V
P
L
V
I
M
----
V
F
V
Y
S
---
R
V
F
Q
E
A
K
R
Q
L
N
I
F
E
M
L
R
I
--------
D
E
G
L
R
L
K
I
Y
K
D
T
E
G
Y
Y
T
I
G
I
G
H
L
L
T
K
S
P
S
L
N
A
A
K
S
E
L
D
K
A
I
G
R
N
T
N
G
V
I
T
K
D
E
A
E
K
L
F
N
Q
D
V
D
A
A
V
R
G
I
L
R
N
A
K
L
K
P
V
Y
D
S
L
D
A
V
R
R
A
A
L
I
N
M
V
F
Q
M
G
E
T
G
V
A
G
F
T
N
S
L
R
M
L
Q
Q
K
R
W
D
E
A
A
V
-
N
L
A
K
S
R
W
Y
N
Q
T
P
N
R
A
--
K
R
V
I
T
T
F
R
T
GTWDAYKFC
L
K
E
H
K
A
L
K
T
L
G
I
I
M
G
T
F
T
L
C
W
L
P
F
F
I
V
N
I
V
H
V
I
QDNLIR
K
E
V
Y
I
L
L
N
W
I
G
Y
V
N
S
G
F
N
PLIYCRS
P
D
F
R
I
A
F
Q
E
L
L
CL
29
Fugue
32.12
13%
23
- C2 -
-
5B22
2
NECT3_MOUSE
A:
[1-209]
------------------------------------------------
P
S
-
I
I
---
V
E
P
H
V
T
A
V
W
G
K
N
V
S
L
K
C
L
I
-----
E
V
N
E
T
I
T
Q
I
S
W
E
K
I
H
---------
G
K
S
T
Q
T
V
A
V
H
H
----
P
Q
Y
G
F
S
V
Q
G
D
Y
Q
G
R
V
L
F
K
N
-------
Y
S
L
N
------------------------------------------
D
A
T
I
T
L
H
N
I
G
F
S
D
S
G
K
Y
I
C
K
A
V
T
F
PL
G
N
A
Q
S
S
T
---
T
V
T
V
L
V
E
P
T
V
S
L
I
K
G
P
D
S
--------
L
I
D
G
-----
G
N
E
T
V
A
A
V
C
V
A
A
T
G
K
P
V
A
Q
I
D
W
E
G
D
L
G
E
M
E
S
S
T
T
S
F
P
N
E
T
A
T
I
V
S
Q
Y
K
L
F
P
T
R
F
A
R
G
R
R
I
T
C
V
V
K
H
P
A
L
E
K
D
I
R
Y
S
F
I
L
D
I
Q
------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
30.04
17%
77
- C6 -
-
1W8X
-
VP16_BPPRD
P:
[1-116]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
K
K
K
L
L
Y
W
V
G
G
G
----
L
V
L
I
L
I
----
W
L
W
F
R
---
N
R
P
A
A
Q
V
A
S
N
W
E
--
G
P
P
Y
--------
M
T
Y
N
Q
P
Q
A
G
S
V
T
L
P
V
A
D
S
I
T
S
Q
L
N
D
Y
A
S
S
L
N
D
Y
L
A
S
Q
A
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
29.10
19%
-11
- C- -
-
4MQV
-
SMAL1_HUMAN
B:
[5-30]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
E
E
Q
R
K
K
I
E
E
N
R
Q
K
--
A
L
A
R
R
A
E
K
L
---------
L
A
---------------------------------------------------------------------------
10
HHSearch
26.55
19%
-
- C1 -
-
2QHQ
-
?
B:
[108-113]
--------------------------------------------------------------------------------------------------------
D
H
Q
N
I
R
N
F
M
V
T
----
G
W
E
G
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
25.94
10%
-99
- C7 -
-
4XYD
1
?
B:
[113-133]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
Q
M
P
N
F
G
L
N
D
E
E
Y
----
R
A
L
S
D
F
----
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
25.70
34%
87
- C7 -
-
1WCH
-
A:
[13-57]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
D
E
L
A
V
L
P
V
V
K
V
L
P
S
G
K
Y
T
G
A
N
L
K
S
V
I
R
----
V
L
R
G
L
L
D
Q
G
I
P
S
K
E
L
E
N
----------------------------------------------------------------------------------------------------
22
Fugue
24.21
15%
83
* C7 *
-
2KV5
-
?
A:
[1-33]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
D
L
M
S
L
V
I
A
P
I
F
V
G
L
V
-
L
E
M
I
S
R
V
L
D
E
E
D
D
S
R
--
K
----------------------------------------------------------------------------------------------
28
Fugue
24.16
24%
104
* C6 *
-
1EHK
2
COXA_THET8
C:
[1-33]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
K
P
K
G
--
A
L
A
V
I
L
V
L
T
---------
L
T
I
L
V
F
W
L
G
V
Y
A
V
F
F
A
R
G
-----------------------------------------------------------
8
HHSearch
21.27
8%
-91
- C4 -
-
3FN2
-
?
B:
[45-69]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Y
Y
G
----
R
G
Y
V
R
I
----
T
D
K
D
G
---
Q
V
I
T
Y
E
D
G
S
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
20.91
15%
-91
- C3 -
-
4NCD
-
?
A:
[1-51]
-----------------------------------------------------------------------
N
F
M
I
-----
Y
P
I
S
K
D
L
K
N
G
N
S
-
E
L
V
R
V
Y
-
S
K
S
K
E
I
Q
Y
I
K
I
Y
T
-
K
----
K
I
I
N
P
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
11.35
21%
-
* C5 *
-
4UU4
-
?
A:
[26-52]
----------------------------------------------------------------
P
-
S
D
R
E
Q
P
I
R
V
-----
Q
A
D
S
A
E
L
D
D
K
Q
G
V
A
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------