@TOME V2.3
(Nov 2016)

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3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : jhp_0235: (2015-12-13 )
MLEIKNLNCVLNSHFSLQNINISLSYSERVAIVGESGSGKSSIANLVMRLNPRFKPHNGEILFETTNLLKESEAFMQHLRGNIIAYIAQDPLSSLNPLHKIGKQMSEAYFLHHKNASQVLLKEQVLNAMKQVQLDEKFLDRYPYELSGGQRQRVCIAMGIINAPKLLICDEPTTALDAQIQNQILDLLKQLSVEKNIALLFISHDLKAVKRLADRVYVLKKGEIVETNLTKELFNDPKHEYSKLLIQASNLPAKNLKALDETLLEVKDFSVYYLQKRFFRPSLKKPLIASVDFSLKAKENIGIIGESGSGKSSLALGLLKLALNSGEEKILGQSVGLLNSKAFKPYRKILQMVFQDPYASLNPRLSIQSILIEALRFAYPKASQQEWHHLAELCLEEVCLNPELLNFYAYELSGGERQRVAIARAIALKPRIILLDEPTSALDKSIQKSVLELLLNLQEKQDLSYLFISHDLDVIKAFCDRVLVVSEGKIVETGAIEEVFDNPKHAYTKRLLESRL

Atome Classification :

(24 SA) -.........10.----.......20........30........40........-50........60........70.......-----.80........-90........100.......110.....--..120......---.130...-....140.......150.......160.--......170.......180.......190.......200.......210.......------220.....-..230.......240........-----250.--......260.......270.......280.......290.......300.......310..--.....-320-.-----......330-----------....-.....340-.....--------..350.......360---------------..----------------------------------------------....-.-..370.....----------.----------.380-----------.........390.......400..-.....410.......420.......430-.........440.......450.......460.......470.......480...------....490.......500.......510....
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) -MLEIKNLNCVLN----SHFSLQNINISLSYSERVAIVGESGSGKSSIANLVMR-LNPRFKPHNGEILFETTNLLKESEAFMQH-----LRGNIIAYIAQ-DPLSSLNPLHKIGKQMSEAYFLHHKNAS--QVLLKEQVLNA---MKQVQLD-EKFLDRYPYELSGGQRQRVCIAMGIINA--PKLLICDEPTTALDAQIQNQILDLLKQLSVEKNIALLFISHDLKAVKRLADRVYVL------KKGEIVET-NLTKELFNDPKHEY-SKLLIQAS-----NLPA--KNLKALDETLLEVKDFSVYYLQKRFFRPSLKKPLIASVDFSLKAKENIGIIGESGSGKSSL--ALGLL-KLA-L-----NSGEEKI-------------LGQS-VGLLNSKA-FKPYR--------KILQMVFQDPYAS-----------------LN----------------------------------------------PRLS-I-QSILIEALRF----------A----------YP-------------KASQQEWHHLAELCLEEVCLNPEL-LNFYAYELSGGERQRVAIARAIALKP---RIILLDEPTSALDKSIQKSVLELLLNLQEKQDLSYLFISHDLDVIKAFCDRVLVV------SEGKIVETGAIEEVFDNPKHAYTKRLLESRL
95 HHSearch 74.8020% -75 - C- -2IW3 EF3A_YEAST A:[440-979] ------EFSLAYG----AKILLNKTQLRLKRARRYGICGPNGCGKSTLMRAIAN-G---------QV--DGFPTQ---------------EECRTVYVEH-DIDG-THSDTSVLDFVFES----G--V-----GTKEAIKDK---LIEFGFT-DEMIAMPISALSGGWKMKLALARAVLRN--ADILLLDEPTNHLDTVNVAWLVNYLNTC----GITSITISHDSVFLDNVCEYIINY------EGLKLRKYKGNFTEFVKKCPAAKAYEELSNTDLEFKFPEPGYLEGVKTKQKAIVKVTNMEFQYPGT-------SKPQITDINFQCSLSSRIAVIGPNGAGKSTL--INVLT-GEL-LP----TSGEVYT-------------HENCRIAYIKQHA-FAHIESHLDKTPSEYIQWRFQTGEDRETMDRANRQ--------INENDAEAMNKIFKIEGTPRRIAGIHSRRKFKNTYEYE----------CSFL-L-GENIGMKSERWVPMMSVDNAWIPRGELVESHSKMVAEVDMKEALASGQFRPLTRKEIEEHCSMLGLDPEIVSHSRIRGLSGGQKVKLVLAAGTWQRP---HLIVLDEPTNYLDRDSLGALSKALKEF----EGGVIIITHSAEFTKNLTEEVWAV------KDGRMTPS-----------------------
4 PsiBlast_PDB 71.8832%-100 - C3 -3TUZ METN_ECOLI C:[30-268] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLL-ERP-------TEGSVLV-------------DGQE-LTTLSESE-LTKAR--------RQIGMIFQH-FNL-----------------LS----------------------------------------------SRTV-F-GNV---ALPL----------E----------LD-------------NTPKDEVKRRVTELLSLVGLGDKH--DSYPSNLSGGQKQRVAIARALASNP---KVLLCDQATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVI------SNGELIEQDTVSEVFSHPKTPLAQKFIQSTL
3 PsiBlast_PDB 71.5732% -90 - C3 -3TUI METN_ECOLI C:[30-268] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLL-ERP-------TEGSVLV-------------DGQE-LTTLSESE-LTKAR--------RQIGMIFQH-FNL-----------------LS----------------------------------------------SRTV-F-GNV---ALPL----------E----------LD-------------NTPKDEVKRRVTELLSLVGLGDKH--DSYPSNLSGGQKQRVAIARALASNP---KVLLCDQATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVI------SNGELIEQDTVSEVFSHPKTPLAQKFIQSTL
23 PsiBlast_CBE 71.2032% -92 - C3 -3TUZ METN_ECOLI D:[30-268] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLL-ERP-------TEGSVLV-------------DGQE-LTTLSESE-LTKAR--------RQIGMIFQH-FNL-----------------LS----------------------------------------------SRTV-F-GNV---ALPL----------E----------LD-------------NTPKDEVKRRVTELLSLVGLGDKH--DSYPSNLSGGQKQRVAIARALASNP---KVLLCDQATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVI------SNGELIEQDTVSEVFSHPKTPLAQKFIQSTL
22 PsiBlast_CBE 70.8432% -92 - C3 -3TUZ METN_ECOLI G:[30-268] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLL-ERP-------TEGSVLV-------------DGQE-LTTLSESE-LTKAR--------RQIGMIFQH-FNL-----------------LS----------------------------------------------SRTV-F-GNV---ALPL----------E----------LD-------------NTPKDEVKRRVTELLSLVGLGDKH--DSYPSNLSGGQKQRVAIARALASNP---KVLLCDQATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVI------SNGELIEQDTVSEVFSHPKTPLAQKFIQSTL
26 PsiBlast_CBE 70.7032% -88 - C3 -3TUI METN_ECOLI D:[30-268] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLL-ERP-------TEGSVLV-------------DGQE-LTTLSESE-LTKAR--------RQIGMIFQH-FNL-----------------LS----------------------------------------------SRTV-F-GNV---ALPL----------E----------LD-------------NTPKDEVKRRVTELLSLVGLGDKH--DSYPSNLSGGQKQRVAIARALASNP---KVLLCDQATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVI------SNGELIEQDTVSEVFSHPKTPLAQKFIQSTL
25 PsiBlast_CBE 70.4532% -91 - C3 -3TUI METN_ECOLI G:[30-268] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLL-ERP-------TEGSVLV-------------DGQE-LTTLSESE-LTKAR--------RQIGMIFQH-FNL-----------------LS----------------------------------------------SRTV-F-GNV---ALPL----------E----------LD-------------NTPKDEVKRRVTELLSLVGLGDKH--DSYPSNLSGGQKQRVAIARALASNP---KVLLCDQATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVI------SNGELIEQDTVSEVFSHPKTPLAQKFIQSTL
24 PsiBlast_CBE 69.8132% -95 - C3 -3TUI METN_ECOLI H:[30-268] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLL-ERP-------TEGSVLV-------------DGQE-LTTLSESE-LTKAR--------RQIGMIFQH-FNL-----------------LS----------------------------------------------SRTV-F-GNV---ALPL----------E----------LD-------------NTPKDEVKRRVTELLSLVGLGDKH--DSYPSNLSGGQKQRVAIARALASNP---KVLLCDQATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVI------SNGELIEQDTVSEVFSHPKTPLAQKFIQSTL
120 Fugue 69.0926% -83 - C3 -3TUZ METN_ECOLI H:[23-362] HMIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNL-LE---RPTEGSVLVDGQELTTLSESELTK-----ARRQIGMIFQHFNLLSSRTVFGNVALPLELD------NTP--KDEVKRRVTEL---LSLVGLG-DKH-DSYPSNLSGGQKQRVAIARALASN--PKVLLCDQATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVI------SNGELIEQ-DTVSEVFSHPKTPL-AQKFIQST-----LHLD--IPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKF--GIMLT-EMH---------GTQQD-------------TQAA-IAWLQEHH-VKVEV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21 PsiBlast_CBE 67.9432% -90 - C3 -3TUZ METN_ECOLI H:[30-268] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLL-ERP-------TEGSVLV-------------DGQE-LTTLSESE-LTKAR--------RQIGMIFQH-FNL-----------------LS----------------------------------------------SRTV-F-GNV---ALPL----------E----------LD-------------NTPKDEVKRRVTELLSLVGLGDKH--DSYPSNLSGGQKQRVAIARALASNP---KVLLCDQATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVI------SNGELIEQDTVSEVFSHPKTPLAQKFIQSTL
14 PsiBlast_PDB 67.7833%-122 - C3 -4YMT - ? J:[16-236] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLKGVTLKVNKGEVVVIIGPSGSGKSTL---LRCI-NLL-E-----EPTKGEV-------------FIDG-VKINNGKVNINKVR--------QKVGMVFQ--HFN-----------------LF----------------------------------------------PHLTAI-ENITLAPVKV----------K-------------------------KMNKKEAEELAVDLLAKVGL-LDK-KDQYPIKLSGGQKQRLAIARALAMQP---EVMLFDEPTSALDPEMVKEVLNVMKQLA-NEGMTMVVVTHEMGFAREVGDRVIFM------DDGVIVEEGTPEEIFYRAKNERTREFLSKIL
1 PsiBlast_PDB 67.3137% -97 - C3 -4FWI ? B:[37-257] ----------------------------------TAIVGESASGKSTIIEAMTKTLPPNGRILSGRVLYKGKDLLTMREEELRK-----IRWKEIALVPQ-AAQQSLNPTMKVIEHFKDTVEAHGVRWS--HSELIEKASEK---LRMVRLNPEAVLNSYPLQLSGGMKQRVLIALALLLD--PVVLILDEPTSALDVLTQAHIIQLLKELKKMLKITLIFVTHDIAVAAELADKVAVI------YGGNLVEY-NSTFQIFKNPLHPY-TRGLINSI-----MPIP--GDPPSLLNPPSGCRFHPRCEYAMEICKKEKPKWIRLDGEAHVACHLYEE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33 PsiBlast_CBE 67.2333%-119 - C3 -4YMU ? A:[16-236] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLKGVTLKVNKGEVVVIIGPSGSGKSTL---LRCI-NLL-E-----EPTKGEV-------------FIDG-VKINNGKVNINKVR--------QKVGMVFQ--HFN-----------------LF----------------------------------------------PHLTAI-ENITLAPVKV----------K-------------------------KMNKKEAEELAVDLLAKVGL-LDK-KDQYPIKLSGGQKQRLAIARALAMQP---EVMLFDEPTSALDPEMVKEVLNVMKQLA-NEGMTMVVVTHEMGFAREVGDRVIFM------DDGVIVEEGTPEEIFYRAKNERTREFLSKIL
13 PsiBlast_PDB 67.2333%-123 - C3 -4YMS - ? J:[16-236] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLKGVTLKVNKGEVVVIIGPSGSGKSTL---LRCI-NLL-E-----EPTKGEV-------------FIDG-VKINNGKVNINKVR--------QKVGMVFQ--HFN-----------------LF----------------------------------------------PHLTAI-ENITLAPVKV----------K-------------------------KMNKKEAEELAVDLLAKVGL-LDK-KDQYPIKLSGGQKQRLAIARALAMQP---EVMLFDEPTSALDPEMVKEVLNVMKQLA-NEGMTMVVVTHEMGFAREVGDRVIFM------DDGVIVEEGTPEEIFYRAKNERTREFLSKIL
107 HHSearch 67.1828%-104 - C3 -1Z47 ? A:[11-247] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSMTIEFVGVEKIYPGG--------ARSVRGVSFQIREGEMVGLLGPSGSGKTTI--LRLIA-GLE-RP----TKGDVWI-------------GGKR-VTDLP------PQK--------RNVGLVFQNYA-------------------LF----------------------------------------------QHMT-V-YDNVSFGLRE----------K----------R---------------VPKDEMDARVRELLRFMRLE-SY-ANRFPHELSGGQQQRVALARALAPRP---QVLLFDEPFAAIDTQIRRELRTFVRQVHDEMGVTSVFVTHDQEEALEVADRVLVL------HEGNVEQFGTPEEVYEKPGTLFVASFIGESN
15 PsiBlast_PDB 66.9333%-119 - C3 -4YMU ? J:[16-236] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLKGVTLKVNKGEVVVIIGPSGSGKSTL---LRCI-NLL-E-----EPTKGEV-------------FIDG-VKINNGKVNINKVR--------QKVGMVFQ--HFN-----------------LF----------------------------------------------PHLTAI-ENITLAPVKV----------K-------------------------KMNKKEAEELAVDLLAKVGL-LDK-KDQYPIKLSGGQKQRLAIARALAMQP---EVMLFDEPTSALDPEMVKEVLNVMKQLA-NEGMTMVVVTHEMGFAREVGDRVIFM------DDGVIVEEGTPEEIFYRAKNERTREFLSKIL
101 HHSearch 66.6824% -61 - C4 -2VF7 ? A:[362-839] ---------------------------------------------------------------------------------------------------------------------------------------------V---LLHLGLG-YLGLDRSTPTLSPGELQRLRLATQLYSNLFGVVYVLDEPSAGLHPADTEALLSALENLKR-GGNSLFVVEHDLDVIRR-ADWLVDVGPEAGEKGGEILYS-GPPEGLKHVPESQT-GQYLFADR-----H-TE--PHTPREPAGWLELNGVT--------------RNNLDNLDVRFPLGVMTSVTGVSGSGKSTL--VSQALVDAL-AAHFGQ--GSARLGGDLAQITRLVRVDQKP-IGRTPR----SNMA--------TYTGLFDQVRKLFAATPLAKKRGYNAGRFSFNVKGGRCEHCQGEGWVMVELLFLPSVYAPCPVCHGTRYNAETLEVEYRGKN-I-ADVLALTVDE----------A----------HD-------------FFADESAIFRALDTLREVGLGYLR-LGQPATELSGGEAQRIKLATELRRSGRGGTVYVLDEPTTGLHPADVERLQRQLVKLVD-AGNTVIAVEHKMQVVA-ASDWVLDIGPGAGEDGGRLVAQGTPAEVAQAAG-SVTAPYLRAAL
16 PsiBlast_PDB 66.4633%-120 - C3 -4YMV ? J:[16-236] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLKGVTLKVNKGEVVVIIGPSGSGKSTL---LRCI-NLL-E-----EPTKGEV-------------FIDG-VKINNGKVNINKVR--------QKVGMVFQ--HFN-----------------LF----------------------------------------------PHLTAI-ENITLAPVKV----------K-------------------------KMNKKEAEELAVDLLAKVGL-LDK-KDQYPIKLSGGQKQRLAIARALAMQP---EVMLFDEPTSALDPEMVKEVLNVMKQLA-NEGMTMVVVTHEMGFAREVGDRVIFM------DDGVIVEEGTPEEIFYRAKNERTREFLSKIL
2 PsiBlast_PDB 65.1432% -87 - C3 -3DHW - METN_ECOLI C:[7-245] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLL-ERP-------TEGSVLV-------------DGQE-LTTLSESE-LTKAR--------RQIGMIFQH-FNL-----------------LS----------------------------------------------SRTV-F-GNV---ALPL----------E----------LD-------------NTPKDEVKRRVTELLSLVGLGDKH--DSYPSNLSGGQKQRVAIARALASNP---KVLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVI------SNGELIEQDTVSEVFSHPKTPLAQKFIQSTL
17 PsiBlast_PDB 65.0933%-121 - C3 -4YMW - ? J:[16-236] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLKGVTLKVNKGEVVVIIGPSGSGKSTL---LRCI-NLL-E-----EPTKGEV-------------FIDG-VKINNGKVNINKVR--------QKVGMVFQ--HFN-----------------LF----------------------------------------------PHLTAI-ENITLAPVKV----------K-------------------------KMNKKEAEELAVDLLAKVGL-LDK-KDQYPIKLSGGQKQRLAIARALAMQP---EVMLFDEPTSALDPEMVKEVLNVMKQLA-NEGMTMVVVTHEMGFAREVGDRVIFM------DDGVIVEEGTPEEIFYRAKNERTREFLSKIL
32 PsiBlast_CBE 64.6333%-120 - C3 -4YMV ? A:[16-236] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLKGVTLKVNKGEVVVIIGPSGSGKSTL---LRCI-NLL-E-----EPTKGEV-------------FIDG-VKINNGKVNINKVR--------QKVGMVFQ--HFN-----------------LF----------------------------------------------PHLTAI-ENITLAPVKV----------K-------------------------KMNKKEAEELAVDLLAKVGL-LDK-KDQYPIKLSGGQKQRLAIARALAMQP---EVMLFDEPTSALDPEMVKEVLNVMKQLA-NEGMTMVVVTHEMGFAREVGDRVIFM------DDGVIVEEGTPEEIFYRAKNERTREFLSKIL
10 PsiBlast_PDB 62.4732% -99 - C3 -4U00 ? A:[19-239] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLKGIHLEVAPGEKLVIIGPSGSGKSTL--IRTIN-RLEDF-----QEGEVVV-------------DGLS-VK--DDRA-LREIR--------REVGMVFQQ--FN-----------------LF----------------------------------------------PHMT-VLENVTLAPMRV----------RR---------WP-------------REKAEK---KALELLERVGILDQA-RK-YPAQLSGGQQQRVAIARALAMEP---KIMLFDEPTSALDPEMVGEVLDVMRDLAQG-GMTMVVVTHEMGFAREVADRVVFM------DGGQIVEEGRPEEIFTRPKEERTRSFLQRVL
70 PsiBlast_CBE 45.1731% -85 - C3 -4S0F ? A:[505-725] ---------------------LKNINLTIPKGKTVAIVGESGSGKTTLAKLLMN-F---YSPEKGDILINGHSIKNIS---LEL-----IRKKI-AFVSQ-D-------VFIFSGTVKENLCLGNENVDMDEIIKAAKMANAHDFIEKLPLKYDTFLNESGANLSEGQKQRLAIARALLKK--PDILILDQATSNLDSITENHIKDAIYGL--EDDVTVIIIAHRLSTIVN-CDKIYLL------KDGEIVES-GSHTELIA-LKGCY-FKMWKQTE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47 PsiBlast_CBE 43.8231% -81 - C3 -2FF7 A:[25-241] ---------------------LDNINLSIKQGEVIGIVGRSGSGKSTLTKLIQR-F---YIPENGQVLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSIIDNISLANP----GMSVEKVIY-----AA--KLAGAHDFISE---LREGY---NTIVGEQGAGLSGGQRQRIAIARALVNN--PKILIFDEATSALDYESEHVIMRNMHKIC--KGRTVIIIAHRLSTVKN-ADRIIVM------EKGKIVEQ-GKHKELLSEPESLY-SYLYQLQS-----D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------