@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu02430: (2016-06-04 )
MKELIKEHQKDINPALQLHDWVEYYRPFAANGQSANYIPALGKVNDSQLGICVLEPDGTMIHAGDWNVSFTMQSISKVISFIAACMSRGIPYVLDRVDVEPTGDAFNSIIRLEINKPGKPFNPMINAGALTIASILPGESAYEKLEFLYSVMETLIGKRPRIHEEVFRSEWETAHRNRALAYYLKETNFLEAEVEETLEVYLKQCAMESTTEDIALIGLILAHDGYHPIRHEQVIPKDVAKLAKALMLTCGMYNASGKYAAFVGVPAKSGVSGGIMALVPPSARREQPFQSGCGIGIYGPAIDEYGNSLTGGMLLKHMAQEWELSIF
Atome Classification :
(28 SA)
---------------------------------------------------------------.........10....----..----..20.....---...30--------.........40........50........60........70........80........90........100.......110....-...120.......130....--.-.-.--140.........150.....-..-160........170.......180.......190-.--.-.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.....-------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------
M
K
E
L
I
K
E
H
Q
K
DIN
P
A
----
L
Q
----
L
H
D
W
V
E
Y
Y
R
---
P
FAA---------NGQSANYIPALGKVNDSQ
L
G
I
C
V
LEPDG
T
M
I
H
AGDW
N
V
S
F
T
M
Q
S
I
S
K
V
I
S
F
I
A
A
C
M
SRGIP
Y
V
L
D
RVDVEPT
G
D
A
F
N
S
I
I
R
L
E
INK-PGKPFNPMINAGAL
T
I
A
S
IL--P-G-
E
--
S
--
A
Y
E
K
L
E
F
L
Y
S
V
M
E
T
L
IG-KR-P-
R
I
H
E
E
V
F
R
S
E
W
E
T
A
HRNR
A
L
A
Y
Y
LKETN
F
L
---
E
--
A
-
E
V
E
E
T
L
E
V
Y
L
K
Q
CAMESTT
E
D
I
A
L
I
G
L
I
LAHDGYHPI
R
H
EQV
I
P
K
D
V
A
K
L
A
K
A
L
M
L
T
CGMYNASG
K
Y
A
A
F
VGVPAKSGVSG
G
I
M
A
LVPPSARREQPFQSGCGIGIYGP
A
I
D
EYGNSL
T
G
G
M
L
L
K
H
M
A
Q
E
WELSIF-------------------------------------------------------------------------------------------
57
HHSearch
89.41
99%
-113
- C6 -
1MKI
4
GLSA1_BACSU
A:
[4-330]
---------------------------------------------------------------
M
K
E
L
I
-------
N
P
A
----
L
Q
----
L
H
D
W
V
E
Y
Y
R
---
P
F
A
A
---------
N
G
Q
S
A
N
---------
D
S
Q
L
G
I
C
V
L
E
P
D
G
T
M
I
H
A
G
D
W
N
V
S
F
T
M
Q
S
I
S
K
V
I
S
F
I
A
A
C
M
S
R
G
I
P
Y
V
L
D
R
V
D
V
E
P
T
G
D
A
F
N
S
I
I
R
-
L
E
I
N
K
P
G
K
P
F
N
P
M
I
N
A
G
A
L
T
I
A
S
I
L
--
P
-
G
-
E
--
S
--
A
Y
E
K
L
E
F
L
Y
S
V
M
E
T
L
I
G
-
K
R
-
P
-
R
I
H
E
E
V
F
R
S
E
W
E
T
A
H
R
N
R
A
L
A
Y
Y
L
K
E
T
N
F
L
---
E
--
A
-
E
V
E
E
T
L
E
V
Y
L
K
Q
C
A
M
E
S
T
T
E
D
I
A
L
I
G
L
I
L
A
H
D
G
Y
H
P
I
R
H
E
Q
V
I
P
K
D
V
A
K
L
A
K
A
L
M
L
T
C
G
M
Y
N
A
S
G
K
Y
A
A
F
V
G
V
P
A
K
S
G
V
S
G
G
I
M
A
L
V
P
P
S
A
R
R
E
Q
P
F
Q
S
G
C
G
I
G
I
Y
G
P
A
I
D
E
Y
G
N
S
L
T
G
G
M
L
L
K
H
M
A
Q
E
W
E
L
S
I
F
-------------------------------------------------------------------------------------------
1
PsiBlast_PDB
89.24
100%
-119
- C6 -
3AGF
-
GLSA1_BACSU
A:
[13-327]
---------------------------------------------------------------------------
N
P
A
----
L
Q
----
L
H
D
W
V
E
Y
Y
R
---
P
F
A
A
---------
N
G
Q
------------
D
S
Q
L
G
I
C
V
L
E
P
D
G
T
M
I
H
A
G
D
W
N
V
S
F
T
M
Q
S
I
S
K
V
I
S
F
I
A
A
C
M
S
R
G
I
P
Y
V
L
D
R
V
D
V
E
P
T
G
D
A
F
N
S
I
I
R
L
E
I
N
K
-
P
G
K
P
F
N
P
M
I
N
A
G
A
L
T
I
A
S
I
L
--
P
-
G
-
E
--
S
--
A
Y
E
K
L
E
F
L
Y
S
V
M
E
T
L
I
G
-
K
R
-
P
-
R
I
H
E
E
V
F
R
S
E
W
E
T
A
H
R
N
R
A
L
A
Y
Y
L
K
E
T
N
F
L
---
E
--
A
-
E
V
E
E
T
L
E
V
Y
L
K
Q
C
A
M
E
S
T
T
E
D
I
A
L
I
G
L
I
L
A
H
D
G
Y
H
P
I
R
H
E
Q
V
I
P
K
D
V
A
K
L
A
K
A
L
M
L
T
C
G
M
Y
N
A
S
G
K
Y
A
A
F
V
G
V
P
A
K
S
G
V
S
G
G
I
M
A
L
V
P
P
S
----
Q
P
F
Q
S
G
C
G
I
G
I
Y
G
P
A
I
D
E
Y
G
N
S
L
T
G
G
M
L
L
K
H
M
A
Q
E
W
E
L
S
I
F
-------------------------------------------------------------------------------------------
2
PsiBlast_PDB
88.82
96%
-126
- C6 -
2OSU
1
GLSA1_BACSU
A:
[5-330]
----------------------------------------------------------------
K
E
L
I
K
E
H
---
I
N
P
A
----
L
Q
----
L
H
D
W
V
E
Y
Y
R
---
P
F
A
A
---------
N
G
Q
S
A
N
Y
I
P
A
L
G
K
V
N
D
S
Q
L
G
I
C
V
L
E
P
D
G
T
M
I
H
A
G
D
W
N
V
S
F
T
M
Q
S
I
S
K
V
I
S
F
I
A
A
C
M
S
R
G
I
P
Y
V
L
D
R
V
D
V
E
-----------------
P
G
K
P
F
N
P
M
I
N
A
G
A
L
T
I
A
S
I
L
--
P
-
G
-
E
--
S
--
A
Y
E
K
L
E
F
L
Y
S
V
M
E
T
L
I
G
-
K
R
-
P
-
R
I
H
E
E
V
F
R
S
E
W
E
T
A
H
R
N
R
A
L
A
Y
Y
L
K
E
T
N
F
L
---
E
--
A
-
E
V
E
E
T
L
E
V
Y
L
K
Q
C
A
M
E
S
T
T
E
D
I
A
L
I
G
L
I
L
A
H
D
G
Y
H
P
I
R
H
E
Q
V
I
P
K
D
V
A
K
L
A
K
A
L
M
L
T
C
G
M
Y
N
A
S
G
K
Y
A
A
F
V
G
V
P
A
K
S
G
V
S
G
G
I
M
A
L
V
P
P
S
A
---
Q
P
F
Q
S
G
C
G
I
G
I
Y
G
P
A
I
D
E
Y
G
N
S
L
T
G
G
M
L
L
K
H
M
A
Q
E
W
E
L
S
I
F
-------------------------------------------------------------------------------------------
3
PsiBlast_PDB
86.64
96%
-122
- C6 -
3BRM
1
GLSA1_BACSU
A:
[16-330]
---------------------------------------------------------------------------
N
P
A
----
L
Q
----
L
H
D
W
V
E
Y
Y
R
---
P
F
A
A
---------
N
G
Q
S
A
---
P
A
L
G
K
-
N
D
S
Q
L
G
I
C
V
L
E
P
D
G
T
M
I
H
A
G
D
W
N
V
S
F
T
M
Q
S
I
S
K
V
I
S
F
I
A
A
C
M
S
R
G
I
P
Y
V
L
D
R
V
D
V
E
P
------------------
K
P
F
N
P
M
I
N
A
G
A
L
T
I
A
S
I
L
--
P
-
G
-
E
--
S
--
A
Y
E
K
L
E
F
L
Y
S
V
M
E
T
L
I
G
-
K
R
-
P
-
R
I
H
E
E
V
F
R
S
E
W
E
T
A
H
R
N
R
A
L
A
Y
Y
L
K
E
T
N
F
L
---
E
--
A
-
E
V
E
E
T
L
E
V
Y
L
K
Q
C
A
M
E
S
T
T
E
D
I
A
L
I
G
L
I
L
A
H
D
G
Y
H
P
I
R
H
E
Q
V
I
P
K
D
V
A
K
L
A
K
A
L
M
L
T
C
G
M
Y
N
A
S
G
K
Y
A
A
F
V
G
V
P
A
K
S
G
V
S
G
G
I
M
A
L
V
P
P
S
----
Q
P
F
Q
S
G
C
G
I
G
I
Y
G
P
A
I
D
E
Y
G
N
S
L
T
G
G
M
L
L
K
H
M
A
Q
E
W
E
L
S
I
F
-------------------------------------------------------------------------------------------
58
HHSearch
74.04
49%
-132
* C6 *
2PBY
-
GLSA_GEOKA
A:
[5-308]
----------------------------------------------------------------------------
N
Q
----
E
E
----
L
V
R
F
V
E
E
A
K
---
Q
Y
A
R
---------
Y
G
K
V
A
D
Y
I
P
A
L
G
K
A
N
P
N
E
L
S
I
A
I
Y
T
P
D
D
E
V
V
S
A
G
D
V
T
V
K
V
T
L
Q
S
I
S
K
I
I
A
L
A
L
V
L
I
D
R
G
E
D
E
V
F
H
K
V
G
M
E
P
------------------
K
P
L
N
P
M
I
N
A
G
A
L
V
V
T
S
M
I
--
Q
-
G
-
G
--
S
--
V
S
E
R
L
E
R
L
L
A
F
V
R
R
L
A
G
-
N
E
R
I
-
S
Y
S
D
E
V
A
R
S
E
F
E
T
A
F
L
N
R
S
L
C
Y
F
L
K
Q
H
R
I
I
---
D
--
E
-
D
V
E
E
L
M
E
L
Y
T
K
Q
C
A
I
E
M
T
C
I
D
L
A
R
I
G
L
V
L
A
L
D
G
R
D
P
H
S
S
E
P
L
M
P
L
D
V
A
R
I
C
K
T
F
M
V
T
C
G
M
Y
N
S
S
G
E
F
A
I
K
V
G
I
P
A
K
S
G
V
S
G
G
I
L
A
A
V
P
G
----------
R
C
G
I
G
V
F
G
P
A
L
D
D
K
G
N
S
L
T
G
V
K
L
L
E
R
L
S
K
T
Y
S
L
S
I
F
-------------------------------------------------------------------------------------------
4
PsiBlast_PDB
73.47
48%
-134
- C6 -
2PBY
-
GLSA_GEOKA
A:
[8-308]
-----------------------------------------------------------------------------------
E
----
L
V
R
F
V
E
E
A
K
---
Q
Y
A
R
---------
Y
G
K
V
A
D
Y
I
P
A
L
G
K
A
N
P
N
E
L
S
I
A
I
Y
T
P
D
D
E
V
V
S
A
G
D
V
T
V
K
V
T
L
Q
S
I
S
K
I
I
A
L
A
L
V
L
I
D
R
G
E
D
E
V
F
H
K
V
G
M
E
P
------------------
K
P
L
N
P
M
I
N
A
G
A
L
V
V
T
S
M
I
--
Q
-
G
-
G
--
S
--
V
S
E
R
L
E
R
L
L
A
F
V
R
R
L
A
G
N
E
R
-
I
-
S
Y
S
D
E
V
A
R
S
E
F
E
T
A
F
L
N
R
S
L
C
Y
F
L
K
Q
H
R
I
I
---
D
--
E
-
D
V
E
E
L
M
E
L
Y
T
K
Q
C
A
I
E
M
T
C
I
D
L
A
R
I
G
L
V
L
A
L
D
G
R
D
P
H
S
S
E
P
L
M
P
L
D
V
A
R
I
C
K
T
F
M
V
T
C
G
M
Y
N
S
S
G
E
F
A
I
K
V
G
I
P
A
K
S
G
V
S
G
G
I
L
A
A
V
P
----------
G
R
C
G
I
G
V
F
G
P
A
L
D
D
K
G
N
S
L
T
G
V
K
L
L
E
R
L
S
K
T
Y
S
L
S
I
F
-------------------------------------------------------------------------------------------
48
Fugue
72.75
31%
-127
- C6 -
3UO9
4
GLSK_HUMAN
A:
[67-489]
PS
L
E
D
L
L
F
Y
T
I
A
E
GQEKIP
V
H
K
F
I
T
A
L
K
S
T
GLRTSDPRL
K
E
C
M
D
M
L
R
L
T
L
Q
T
TSDGV
M
L
D
K
D
L
F
K
K
C
V
Q
S
N
I
V
L
L
T
Q
A
----
F
R
RKFV
I
P
D
F
M
S
F
T
S
---
H
I
D
E
L
Y
E
S
A
K
K
Q
S
G
G
K
V
A
D
Y
I
P
Q
L
A
K
F
S
P
D
L
W
G
V
S
V
C
T
V
D
G
Q
R
H
S
T
G
D
T
K
V
P
F
C
L
Q
S
C
V
K
P
L
K
Y
A
I
A
V
N
D
L
G
T
E
Y
V
H
R
Y
V
G
K
E
P
S
G
L
R
F
N
K
L
F
L
N
E
----
D
D
K
P
H
N
P
M
V
N
A
G
A
I
V
V
T
S
L
I
K-
Q
-
G
-
V
--
N
--
N
A
E
K
F
D
Y
V
M
Q
F
L
N
K
M
A
G
-
N
E
-
Y
V
G
F
S
N
A
T
F
Q
S
E
R
E
S
G
D
R
N
F
A
I
G
Y
Y
L
K
E
K
K
C
F
---
P
EG
T
-
D
M
V
G
I
L
D
F
Y
F
Q
L
C
S
I
E
V
T
C
E
S
A
S
V
M
A
A
T
L
A
N
G
G
F
C
P
I
T
G
E
R
V
L
S
P
E
A
V
R
N
T
L
S
L
M
H
S
C
G
M
Y
D
F
S
G
Q
F
A
F
H
V
G
L
P
A
K
S
G
V
A
G
G
I
L
L
V
V
P
N
V
----------
M
G
M
M
C
W
S
P
P
L
D
K
M
G
N
S
V
K
G
I
H
F
C
H
D
L
V
S
L
C
N
F
H
N
Y
DNLRHFAKKLDPRREGE--------------------------------------------------------------------------
61
HHSearch
72.26
32%
-124
- C6 -
3UO9
4
GLSK_HUMAN
A:
[147-472]
----------------------------------------------------------------------
R
K
F
V
I
P
D
F
M
S
F
T
S
H
----
I
D
E
L
Y
E
S
A
----
K
K
Q
S
---------
G
G
K
V
A
D
Y
I
P
Q
L
A
K
F
S
P
D
L
W
G
V
S
V
C
T
V
D
G
Q
R
H
S
T
G
D
T
K
V
P
F
C
L
Q
S
C
V
K
P
L
K
Y
A
I
A
V
N
D
L
G
T
E
Y
V
H
R
Y
V
G
K
E
P
S
G
L
R
F
N
K
L
F
--
L
N
-
E
-
D
D
K
P
H
N
P
M
V
N
A
G
A
I
V
V
T
S
L
I
--
K
-
Q
G
V
--
N
--
N
A
E
K
F
D
Y
V
M
Q
F
L
N
K
M
A
G
-
N
E
Y
V
-
G
F
S
N
A
T
F
Q
S
E
R
E
S
G
D
R
N
F
A
I
G
Y
Y
L
K
E
K
K
C
F
PEG
T
--
D
--
M
V
G
I
L
D
F
Y
F
Q
L
C
S
I
E
V
T
C
E
S
A
S
V
M
A
A
T
L
A
N
G
G
F
C
P
I
T
G
E
R
V
L
S
P
E
A
V
R
N
T
L
S
L
M
H
S
C
G
M
Y
D
F
S
G
Q
F
A
F
H
V
G
L
P
A
K
S
G
V
A
G
G
I
L
L
V
V
P
N
----------
V
M
G
M
M
C
W
S
P
P
L
D
K
M
G
N
S
V
K
G
I
H
F
C
H
D
L
V
S
L
C
N
F
H
N
Y
-------------------------------------------------------------------------------------------
50
Fugue
70.55
36%
-108
- C6 -
3IF5
-
?
A:
[1-448]
---------------------------------------------------------------
M
R
H
P
I
P
D
Y
L
A
S
L
V
T
E
----
L
G
----
A
V
N
----------------------
P
G
E
T
A
Q
Y
I
P
V
L
A
E
A
D
P
D
R
F
G
I
A
L
A
T
P
T
G
R
L
H
C
A
G
D
A
D
V
E
F
T
I
Q
S
A
S
K
P
F
T
Y
A
A
A
L
V
D
R
G
F
A
A
V
D
R
Q
V
G
L
N
P
S
G
E
A
F
N
E
-
L
S
L
E
-
A
E
-
S
H
R
P
D
N
A
M
I
N
A
G
A
L
A
V
H
Q
L
L
--
V
-
G
-
P
EA
S
--
R
K
E
R
L
D
R
A
V
E
I
M
S
L
L
A
G
-
R
R
-
L
-
S
V
D
W
E
T
Y
E
S
E
M
A
V
S
D
R
N
L
S
L
A
H
M
L
R
S
Y
G
V
L
---
Q
--
D
-
S
A
E
E
I
V
A
G
Y
V
A
Q
C
A
V
L
V
T
V
K
D
L
A
V
M
G
A
C
L
A
T
G
G
I
H
P
M
T
G
E
R
M
L
P
S
I
V
A
R
R
V
V
S
V
M
T
S
S
G
M
Y
D
A
A
G
Q
W
L
A
D
V
G
I
P
A
K
S
G
V
A
G
G
V
L
G
A
L
P
G
R
----------
V
G
I
G
V
F
S
P
R
L
D
E
V
G
N
S
A
R
G
V
L
A
C
R
R
L
S
E
D
F
R
L
H
L
M
DGDSLGGTAVRFVEREGD
R
V
F
L
H
L
Q
G
VIR
F
G
G
A
E
A
V
L
D
A
L
T
D
LRTGIR
T
V
V
L
N
LARVDRID
D
V
G
R
R
L
I
A
E
G
V
R
R
L
Q
A
D
G
V
R
V
E
V
EDPERIL
62
HHSearch
69.13
35%
-116
- C6 -
3AGD
-
?
A:
[3-317]
--------------------------------------------------------------------------
H
P
I
P
----
D
Y
----
L
A
S
L
V
T
E
L
G
----
A
V
N
---------
P
G
E
T
A
Q
Y
I
P
V
L
A
E
A
D
P
D
R
F
G
I
A
L
A
T
P
T
G
R
L
H
C
A
G
D
A
D
V
E
F
T
I
Q
S
A
S
K
P
F
T
Y
A
A
A
L
V
D
R
G
F
A
A
V
D
R
Q
V
G
L
N
P
S
G
E
A
F
N
E
L
S
--
L
E
A
E
-
S
H
R
P
D
N
A
M
I
N
A
G
A
L
A
V
H
Q
L
L
--
V
-
G
-
P
--
E
AS
R
K
E
R
L
D
R
A
V
E
I
M
S
L
L
A
G
-
R
R
-
L
-
S
V
D
W
E
T
Y
E
S
E
M
A
V
S
D
R
N
L
S
L
A
H
M
L
R
S
Y
G
V
L
---
Q
--
D
-
S
A
E
E
I
V
A
G
Y
V
A
Q
C
A
V
L
V
T
V
K
D
L
A
V
M
G
A
C
L
A
T
G
G
I
H
P
M
T
G
E
R
M
L
P
S
I
V
A
R
R
V
V
S
V
M
T
S
S
G
M
Y
D
A
A
G
Q
W
L
A
D
V
G
I
P
A
K
S
G
V
A
G
G
V
L
G
A
L
P
G
----------
R
V
G
I
G
V
F
S
P
R
L
D
E
V
G
N
S
A
R
G
V
L
A
C
R
R
L
S
E
D
F
R
L
H
L
M
-------------------------------------------------------------------------------------------
60
HHSearch
67.55
31%
-137
- C6 -
4BQM
5
GLSL_HUMAN
A:
[21-333]
-----------------------------------------------------------------------
Q
S
M
I
P
D
F
E
E
F
T
G
H
----
V
D
R
I
F
E
D
V
K
----
E
L
-------------------------
P
D
L
W
G
V
S
L
C
T
V
D
G
Q
R
H
S
V
G
H
T
K
I
P
F
C
L
Q
S
C
V
K
P
L
T
Y
A
I
S
I
S
T
L
G
T
D
Y
V
H
K
F
V
G
K
E
P
S
------
L
S
--
L
N
-
E
-
E
G
I
P
H
N
P
M
V
N
A
G
A
I
V
V
S
S
L
I
--
K
-
M
-
D
C-
N
--
K
A
E
K
F
D
F
V
L
Q
Y
L
N
K
M
A
G
-
N
E
Y
M
-
G
F
S
N
A
T
F
Q
S
E
K
E
T
G
D
R
N
Y
A
I
G
Y
Y
L
K
E
K
K
C
F
---
P
K-
G
V
D
M
M
A
A
L
D
L
Y
F
Q
L
C
S
V
E
V
T
C
E
S
G
S
V
M
A
A
T
L
A
N
G
G
I
C
P
I
T
G
E
S
V
L
S
A
E
A
V
R
N
T
L
S
L
M
H
S
C
G
M
Y
D
F
S
G
Q
F
A
F
H
V
G
L
P
A
K
S
A
V
S
G
A
I
L
L
V
V
P
N
----------
V
M
G
M
M
C
L
S
P
P
L
D
K
L
G
N
S
H
R
G
T
S
F
C
Q
K
L
V
S
L
F
N
F
H
N
Y
-------------------------------------------------------------------------------------------
11
PsiBlast_PDB
67.20
36%
-114
- C6 -
3AGE
1
?
A:
[22-310]
------------------------------------------------------------------------------------------------------------------
G
E
T
A
Q
Y
I
P
V
L
A
E
A
D
P
D
R
F
G
I
A
L
A
T
P
T
G
R
L
H
C
A
G
D
A
D
V
E
F
T
I
Q
S
A
S
K
P
F
T
Y
A
A
A
L
V
D
R
G
F
A
A
V
D
R
Q
V
G
L
N
P
S
G
E
A
F
N
E
L
-
S
L
E
A
E
S
-
H
-
R
P
D
N
A
M
I
N
A
G
A
L
A
V
H
Q
L
L
VG
P
-
E
-
A
--
S
--
R
K
E
R
L
D
R
A
V
E
I
M
S
L
L
A
G
-
R
R
-
L
-
S
V
D
W
E
T
Y
E
S
E
M
A
V
S
D
R
N
L
S
L
A
H
M
L
R
S
Y
G
V
L
---
Q
--
D
-
S
A
E
E
I
V
A
G
Y
V
A
Q
C
A
V
L
V
T
V
K
D
L
A
V
M
G
A
C
L
A
T
G
G
I
H
P
M
T
G
E
R
M
L
P
S
I
V
A
R
R
V
V
S
V
M
T
S
S
G
M
Y
D
A
A
G
Q
W
L
A
D
V
G
I
P
A
K
S
G
V
A
G
G
V
L
G
A
L
P
G
R
----------
V
G
I
G
V
F
S
P
R
L
D
E
V
G
N
S
A
R
G
V
L
A
C
R
R
L
S
E
D
F
R
L
H
L
M
-------------------------------------------------------------------------------------------
23
PsiBlast_CBE
66.46
36%
-109
- C6 -
3AGE
1
?
B:
[22-319]
------------------------------------------------------------------------------------------------------------------
G
E
T
A
Q
Y
I
P
V
L
A
E
A
D
P
D
R
F
G
I
A
L
A
T
P
T
G
R
L
H
C
A
G
D
A
D
V
E
F
T
I
Q
S
A
S
K
P
F
T
Y
A
A
A
L
V
D
R
G
F
A
A
V
D
R
Q
V
G
L
N
P
S
G
E
A
F
N
E
L
-
S
L
E
A
E
S
-
H
-
R
P
D
N
A
M
I
N
A
G
A
L
A
V
H
Q
L
L
VG
P
-
E
-
A
--
S
--
R
K
E
R
L
D
R
A
V
E
I
M
S
L
L
A
G
-
R
R
-
L
-
S
V
D
W
E
T
Y
E
S
E
M
A
V
S
D
R
N
L
S
L
A
H
M
L
R
S
Y
G
V
L
---
Q
--
D
-
S
A
E
E
I
V
A
G
Y
V
A
Q
C
A
V
L
V
T
V
K
D
L
A
V
M
G
A
C
L
A
T
G
G
I
H
P
M
T
G
E
R
M
L
P
S
I
V
A
R
R
V
V
S
V
M
T
S
S
G
M
Y
D
A
A
G
Q
W
L
A
D
V
G
I
P
A
K
S
G
V
A
G
G
V
L
G
A
L
P
G
R
----------
V
G
I
G
V
F
S
P
R
L
D
E
V
G
N
S
A
R
G
V
L
A
C
R
R
L
S
E
D
F
R
L
H
L
M
-------------------------------------------------------------------------------------------
59
HHSearch
66.29
34%
-104
- C6 -
1U60
8
GLSA1_ECOLI
A:
[4-308]
-----------------------------------------------------------------------------
A
----
N
K
----
L
Q
Q
A
V
D
Q
A
Y
T
Q
F
H
S
L
N
---------
G
G
Q
N
A
D
Y
I
P
F
L
A
N
V
P
G
Q
L
A
A
V
A
I
V
T
C
D
G
N
V
Y
S
A
G
D
S
D
Y
R
F
A
L
E
S
I
S
K
V
C
T
L
A
L
A
L
E
D
V
G
P
Q
A
V
Q
D
K
I
G
A
D
P
T
G
L
P
F
N
S
V
I
A
-
L
E
L
H
-
G
G
K
P
L
S
P
L
V
N
A
G
A
I
A
T
T
S
L
I
--
N
-
A
-
E
--
N
--
V
E
Q
R
W
Q
R
I
L
H
I
Q
Q
Q
L
A
G
-
E
Q
-
V
-
A
L
S
D
E
V
N
Q
S
E
Q
T
T
N
F
H
N
R
A
I
A
W
L
L
Y
S
A
G
Y
L
---
Y
--
C
-
D
A
M
E
A
C
D
V
Y
T
R
Q
C
S
T
L
L
N
T
I
E
L
A
T
L
G
A
T
L
A
A
G
G
V
N
P
L
T
H
K
R
V
L
Q
A
D
N
V
P
Y
I
L
A
E
M
M
M
E
G
L
Y
G
R
S
G
D
W
A
Y
R
V
G
L
P
G
K
S
G
V
G
G
G
I
L
A
V
V
P
G
----------
V
M
G
I
A
A
F
S
P
P
L
D
E
D
G
N
S
V
R
G
Q
K
M
V
A
S
V
A
K
Q
L
G
Y
N
V
F
-------------------------------------------------------------------------------------------
10
PsiBlast_PDB
65.96
36%
-114
- C6 -
3AGD
-
?
A:
[22-317]
------------------------------------------------------------------------------------------------------------------
G
E
T
A
Q
Y
I
P
V
L
A
E
A
D
P
D
R
F
G
I
A
L
A
T
P
T
G
R
L
H
C
A
G
D
A
D
V
E
F
T
I
Q
S
A
S
K
P
F
T
Y
A
A
A
L
V
D
R
G
F
A
A
V
D
R
Q
V
G
L
N
P
S
G
E
A
F
N
E
L
-
S
L
E
A
E
S
-
H
-
R
P
D
N
A
M
I
N
A
G
A
L
A
V
H
Q
L
L
VG
P
-
E
-
A
--
S
--
R
K
E
R
L
D
R
A
V
E
I
M
S
L
L
A
G
-
R
R
-
L
-
S
V
D
W
E
T
Y
E
S
E
M
A
V
S
D
R
N
L
S
L
A
H
M
L
R
S
Y
G
V
L
---
Q
--
D
-
S
A
E
E
I
V
A
G
Y
V
A
Q
C
A
V
L
V
T
V
K
D
L
A
V
M
G
A
C
L
A
T
G
G
I
H
P
M
T
G
E
R
M
L
P
S
I
V
A
R
R
V
V
S
V
M
T
S
S
G
M
Y
D
A
A
G
Q
W
L
A
D
V
G
I
P
A
K
S
G
V
A
G
G
V
L
G
A
L
P
G
R
----------
V
G
I
G
V
F
S
P
R
L
D
E
V
G
N
S
A
R
G
V
L
A
C
R
R
L
S
E
D
F
R
L
H
L
M
-------------------------------------------------------------------------------------------
8
PsiBlast_PDB
65.24
36%
-110
- C6 -
3IHA
1
?
A:
[22-320]
------------------------------------------------------------------------------------------------------------------
G
E
T
A
Q
Y
I
P
V
L
A
E
A
D
P
D
R
F
G
I
A
L
A
T
P
T
G
R
L
H
C
A
G
D
A
D
V
E
F
T
I
Q
S
A
S
K
P
F
T
Y
A
A
A
L
V
D
R
G
F
A
A
V
D
R
Q
V
G
L
N
P
S
G
E
A
F
N
E
L
-
S
L
E
A
E
S
-
H
-
R
P
D
N
A
M
I
N
A
G
A
L
A
V
H
Q
L
L
VG
P
-
E
-
A
--
S
--
R
K
E
R
L
D
R
A
V
E
I
M
S
L
L
A
G
-
R
R
-
L
-
S
V
D
W
E
T
Y
E
S
E
M
A
V
S
D
R
N
L
S
L
A
H
M
L
R
S
Y
G
V
L
---
Q
--
D
-
S
A
E
E
I
V
A
G
Y
V
A
Q
C
A
V
L
V
T
V
K
D
L
A
V
M
G
A
C
L
A
T
G
G
I
H
P
M
T
G
E
R
M
L
P
S
I
V
A
R
R
V
V
S
V
M
T
S
S
G
M
Y
D
A
A
G
Q
W
L
A
D
V
G
I
P
A
K
S
G
V
A
G
G
V
L
G
A
L
P
G
R
----------
V
G
I
G
V
F
S
P
R
L
D
E
V
G
N
S
A
R
G
V
L
A
C
R
R
L
S
E
D
F
R
L
H
L
M
-------------------------------------------------------------------------------------------
6
PsiBlast_PDB
65.17
36%
-109
- C6 -
3IH8
-
?
A:
[22-337]
------------------------------------------------------------------------------------------------------------------
G
E
T
A
Q
Y
I
P
V
L
A
E
A
D
P
D
R
F
G
I
A
L
A
T
P
T
G
R
L
H
C
A
G
D
A
D
V
E
F
T
I
Q
S
A
S
K
P
F
T
Y
A
A
A
L
V
D
R
G
F
A
A
V
D
R
Q
V
G
L
N
P
S
G
E
A
F
N
E
L
-
S
L
E
A
E
S
-
H
-
R
P
D
N
A
M
I
N
A
G
A
L
A
V
H
Q
L
L
VG
P
-
E
-
A
--
S
--
R
K
E
R
L
D
R
A
V
E
I
M
S
L
L
A
G
-
R
R
-
L
-
S
V
D
W
E
T
Y
E
S
E
M
A
V
S
D
R
N
L
S
L
A
H
M
L
R
S
Y
G
V
L
---
Q
--
D
-
S
A
E
E
I
V
A
G
Y
V
A
Q
C
A
V
L
V
T
V
K
D
L
A
V
M
G
A
C
L
A
T
G
G
I
H
P
M
T
G
E
R
M
L
P
S
I
V
A
R
R
V
V
S
V
M
T
S
S
G
M
Y
D
A
A
G
Q
W
L
A
D
V
G
I
P
A
K
S
G
V
A
G
G
V
L
G
A
L
P
G
R
----------
V
G
I
G
V
F
S
P
R
L
D
E
V
G
N
S
A
R
G
V
L
A
C
R
R
L
S
E
D
F
R
L
H
L
M
-------------------------------------------------------------------------------------------
21
PsiBlast_CBE
64.76
36%
-111
- C6 -
3IHB
2
?
B:
[22-307]
------------------------------------------------------------------------------------------------------------------
G
E
T
A
Q
Y
I
P
V
L
A
E
A
D
P
D
R
F
G
I
A
L
A
T
P
T
G
R
L
H
C
A
G
D
A
D
V
E
F
T
I
Q
S
A
S
K
P
F
T
Y
A
A
A
L
V
D
R
G
F
A
A
V
D
R
Q
V
G
L
N
P
S
G
E
A
F
N
E
L
-
S
L
E
A
E
S
-
H
-
R
P
D
N
A
M
I
N
A
G
A
L
A
V
H
Q
L
L
VG
P
-
E
-
A
--
S
--
R
K
E
R
L
D
R
A
V
E
I
M
S
L
L
A
G
-
R
R
-
L
-
S
V
D
W
E
T
Y
E
S
E
M
A
V
S
D
R
N
L
S
L
A
H
M
L
R
S
Y
G
V
L
---
Q
--
D
-
S
A
E
E
I
V
A
G
Y
V
A
Q
C
A
V
L
V
T
V
K
D
L
A
V
M
G
A
C
L
A
T
G
G
I
H
P
M
T
G
E
R
M
L
P
S
I
V
A
R
R
V
V
S
V
M
T
S
S
G
M
Y
D
A
A
G
Q
W
L
A
D
V
G
I
P
A
K
S
G
V
A
G
G
V
L
G
A
L
P
G
R
----------
V
G
I
G
V
F
S
P
R
L
D
E
V
G
N
S
A
R
G
V
L
A
C
R
R
L
S
E
D
F
R
L
H
L
M
-------------------------------------------------------------------------------------------
22
PsiBlast_CBE
64.60
36%
-111
- C6 -
3IHA
1
?
B:
[22-317]
------------------------------------------------------------------------------------------------------------------
G
E
T
A
Q
Y
I
P
V
L
A
E
A
D
P
D
R
F
G
I
A
L
A
T
P
T
G
R
L
H
C
A
G
D
A
D
V
E
F
T
I
Q
S
A
S
K
P
F
T
Y
A
A
A
L
V
D
R
G
F
A
A
V
D
R
Q
V
G
L
N
P
S
G
E
A
F
N
E
L
-
S
L
E
A
E
S
-
H
-
R
P
D
N
A
M
I
N
A
G
A
L
A
V
H
Q
L
L
VG
P
-
E
-
A
--
S
--
R
K
E
R
L
D
R
A
V
E
I
M
S
L
L
A
G
-
R
R
-
L
-
S
V
D
W
E
T
Y
E
S
E
M
A
V
S
D
R
N
L
S
L
A
H
M
L
R
S
Y
G
V
L
---
Q
--
D
-
S
A
E
E
I
V
A
G
Y
V
A
Q
C
A
V
L
V
T
V
K
D
L
A
V
M
G
A
C
L
A
T
G
G
I
H
P
M
T
G
E
R
M
L
P
S
I
V
A
R
R
V
V
S
V
M
T
S
S
G
M
Y
D
A
A
G
Q
W
L
A
D
V
G
I
P
A
K
S
G
V
A
G
G
V
L
G
A
L
P
G
R
----------
V
G
I
G
V
F
S
P
R
L
D
E
V
G
N
S
A
R
G
V
L
A
C
R
R
L
S
E
D
F
R
L
H
L
M
-------------------------------------------------------------------------------------------
7
PsiBlast_PDB
64.58
36%
-108
- C6 -
3IH9
-
?
A:
[22-307]
------------------------------------------------------------------------------------------------------------------
G
E
T
A
Q
Y
I
P
V
L
A
E
A
D
P
D
R
F
G
I
A
L
A
T
P
T
G
R
L
H
C
A
G
D
A
D
V
E
F
T
I
Q
S
A
S
K
P
F
T
Y
A
A
A
L
V
D
R
G
F
A
A
V
D
R
Q
V
G
L
N
P
S
G
E
A
F
N
E
L
-
S
L
E
A
E
S
-
H
-
R
P
D
N
A
M
I
N
A
G
A
L
A
V
H
Q
L
L
VG
P
-
E
-
A
--
S
--
R
K
E
R
L
D
R
A
V
E
I
M
S
L
L
A
G
-
R
R
-
L
-
S
V
D
W
E
T
Y
E
S
E
M
A
V
S
D
R
N
L
S
L
A
H
M
L
R
S
Y
G
V
L
---
Q
--
D
-
S
A
E
E
I
V
A
G
Y
V
A
Q
C
A
V
L
V
T
V
K
D
L
A
V
M
G
A
C
L
A
T
G
G
I
H
P
M
T
G
E
R
M
L
P
S
I
V
A
R
R
V
V
S
V
M
T
S
S
G
M
Y
D
A
A
G
Q
W
L
A
D
V
G
I
P
A
K
S
G
V
A
G
G
V
L
G
A
L
P
G
R
----------
V
G
I
G
V
F
S
P
R
L
D
E
V
G
N
S
A
R
G
V
L
A
C
R
R
L
S
E
D
F
R
L
H
L
M
-------------------------------------------------------------------------------------------
9
PsiBlast_PDB
64.49
36%
-111
- C6 -
3IHB
2
?
A:
[22-307]
------------------------------------------------------------------------------------------------------------------
G
E
T
A
Q
Y
I
P
V
L
A
E
A
D
P
D
R
F
G
I
A
L
A
T
P
T
G
R
L
H
C
A
G
D
A
D
V
E
F
T
I
Q
S
A
S
K
P
F
T
Y
A
A
A
L
V
D
R
G
F
A
A
V
D
R
Q
V
G
L
N
P
S
G
E
A
F
N
E
L
-
S
L
E
A
E
S
-
H
-
R
P
D
N
A
M
I
N
A
G
A
L
A
V
H
Q
L
L
VG
P
-
E
-
A
--
S
--
R
K
E
R
L
D
R
A
V
E
I
M
S
L
L
A
G
-
R
R
-
L
-
S
V
D
W
E
T
Y
E
S
E
M
A
V
S
D
R
N
L
S
L
A
H
M
L
R
S
Y
G
V
L
---
Q
--
D
-
S
A
E
E
I
V
A
G
Y
V
A
Q
C
A
V
L
V
T
V
K
D
L
A
V
M
G
A
C
L
A
T
G
G
I
H
P
M
T
G
E
R
M
L
P
S
I
V
A
R
R
V
V
S
V
M
T
S
S
G
M
Y
D
A
A
G
Q
W
L
A
D
V
G
I
P
A
K
S
G
V
A
G
G
V
L
G
A
L
P
G
R
----------
V
G
I
G
V
F
S
P
R
L
D
E
V
G
N
S
A
R
G
V
L
A
C
R
R
L
S
E
D
F
R
L
H
L
M
-------------------------------------------------------------------------------------------
26
PsiBlast_CBE
64.29
34%
-103
- C6 -
1U60
6
GLSA1_ECOLI
B:
[24-308]
------------------------------------------------------------------------------------------------------------------
G
Q
N
A
D
Y
I
P
F
L
A
N
V
P
G
Q
L
A
A
V
A
I
V
T
C
D
G
N
V
Y
S
A
G
D
S
D
Y
R
F
A
L
E
S
I
S
K
V
C
T
L
A
L
A
L
E
D
V
G
P
Q
A
V
Q
D
K
I
G
A
D
P
T
G
L
P
F
N
S
V
I
A
L
E
L
H
G
--
G
K
P
L
S
P
L
V
N
A
G
A
I
A
T
T
S
L
I
--
N
-
A
-
E
--
N
--
V
E
Q
R
W
Q
R
I
L
H
I
Q
Q
Q
L
A
G
-
E
Q
-
V
-
A
L
S
D
E
V
N
Q
S
E
Q
T
T
N
F
H
N
R
A
I
A
W
L
L
Y
S
A
G
Y
L
---
Y
--
C
-
D
A
M
E
A
C
D
V
Y
T
R
Q
C
S
T
L
L
N
T
I
E
L
A
T
L
G
A
T
L
A
A
G
G
V
N
P
L
T
H
K
R
V
L
Q
A
D
N
V
P
Y
I
L
A
E
M
M
M
E
G
L
Y
G
R
S
G
D
W
A
Y
R
V
G
L
P
G
K
S
G
V
G
G
G
I
L
A
V
V
P
G
V
----------
M
G
I
A
A
F
S
P
P
L
D
E
D
G
N
S
V
R
G
Q
K
M
V
A
S
V
A
K
Q
L
G
Y
N
V
F
-------------------------------------------------------------------------------------------
12
PsiBlast_PDB
64.21
34%
-104
- C6 -
1U60
8
GLSA1_ECOLI
A:
[24-308]
------------------------------------------------------------------------------------------------------------------
G
Q
N
A
D
Y
I
P
F
L
A
N
V
P
G
Q
L
A
A
V
A
I
V
T
C
D
G
N
V
Y
S
A
G
D
S
D
Y
R
F
A
L
E
S
I
S
K
V
C
T
L
A
L
A
L
E
D
V
G
P
Q
A
V
Q
D
K
I
G
A
D
P
T
G
L
P
F
N
S
V
I
A
L
E
L
H
G
--
G
K
P
L
S
P
L
V
N
A
G
A
I
A
T
T
S
L
I
--
N
-
A
-
E
--
N
--
V
E
Q
R
W
Q
R
I
L
H
I
Q
Q
Q
L
A
G
-
E
Q
-
V
-
A
L
S
D
E
V
N
Q
S
E
Q
T
T
N
F
H
N
R
A
I
A
W
L
L
Y
S
A
G
Y
L
---
Y
--
C
-
D
A
M
E
A
C
D
V
Y
T
R
Q
C
S
T
L
L
N
T
I
E
L
A
T
L
G
A
T
L
A
A
G
G
V
N
P
L
T
H
K
R
V
L
Q
A
D
N
V
P
Y
I
L
A
E
M
M
M
E
G
L
Y
G
R
S
G
D
W
A
Y
R
V
G
L
P
G
K
S
G
V
G
G
G
I
L
A
V
V
P
G
V
----------
M
G
I
A
A
F
S
P
P
L
D
E
D
G
N
S
V
R
G
Q
K
M
V
A
S
V
A
K
Q
L
G
Y
N
V
F
-------------------------------------------------------------------------------------------
24
PsiBlast_CBE
63.71
34%
-103
- C6 -
1U60
4
GLSA1_ECOLI
D:
[24-308]
------------------------------------------------------------------------------------------------------------------
G
Q
N
A
D
Y
I
P
F
L
A
N
V
P
G
Q
L
A
A
V
A
I
V
T
C
D
G
N
V
Y
S
A
G
D
S
D
Y
R
F
A
L
E
S
I
S
K
V
C
T
L
A
L
A
L
E
D
V
G
P
Q
A
V
Q
D
K
I
G
A
D
P
T
G
L
P
F
N
S
V
I
A
L
E
L
H
G
--
G
K
P
L
S
P
L
V
N
A
G
A
I
A
T
T
S
L
I
--
N
-
A
-
E
--
N
--
V
E
Q
R
W
Q
R
I
L
H
I
Q
Q
Q
L
A
G
-
E
Q
-
V
-
A
L
S
D
E
V
N
Q
S
E
Q
T
T
N
F
H
N
R
A
I
A
W
L
L
Y
S
A
G
Y
L
---
Y
--
C
-
D
A
M
E
A
C
D
V
Y
T
R
Q
C
S
T
L
L
N
T
I
E
L
A
T
L
G
A
T
L
A
A
G
G
V
N
P
L
T
H
K
R
V
L
Q
A
D
N
V
P
Y
I
L
A
E
M
M
M
E
G
L
Y
G
R
S
G
D
W
A
Y
R
V
G
L
P
G
K
S
G
V
G
G
G
I
L
A
V
V
P
G
V
----------
M
G
I
A
A
F
S
P
P
L
D
E
D
G
N
S
V
R
G
Q
K
M
V
A
S
V
A
K
Q
L
G
Y
N
V
F
-------------------------------------------------------------------------------------------
17
PsiBlast_PDB
63.06
34%
-106
- C6 -
3CZD
4
GLSK_HUMAN
A:
[24-296]
-------------------------------------------------------------------------------------------------------
S
---------
G
G
K
V
A
D
Y
I
P
Q
L
A
K
F
S
P
D
L
W
G
V
S
V
C
T
V
D
G
Q
R
H
S
T
G
D
T
K
V
P
F
C
L
Q
S
C
V
K
P
L
K
Y
A
I
A
V
N
D
L
G
T
E
Y
V
H
R
Y
V
G
K
E
P
S
G
L
R
------
L
F
L
N
E
-
D
D
K
P
H
N
P
M
V
N
A
G
A
I
V
V
T
S
L
I
--
K
Q
G
-
V
--
N
--
N
A
E
K
F
D
Y
V
M
Q
F
L
N
K
M
A
G
-
N
E
Y
V
-
G
F
S
N
A
T
F
Q
S
E
R
E
S
G
D
R
N
F
A
I
G
Y
Y
L
K
E
K
K
C
F
---
P
EG
T
-
D
M
V
G
I
L
D
F
Y
F
Q
L
C
S
I
E
V
T
C
E
S
A
S
V
M
A
A
T
L
A
N
G
G
F
C
P
I
T
G
E
R
V
L
S
P
E
A
V
R
N
T
L
S
L
M
H
S
C
G
M
Y
D
F
S
G
Q
F
A
F
H
V
G
L
P
A
K
S
G
V
A
G
G
I
L
L
V
V
P
N
V
M
----------
G
M
M
C
W
S
P
P
L
D
K
M
G
N
S
V
K
G
-----------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
62.95
34%
-105
- C6 -
3VP1
4
GLSK_HUMAN
A:
[24-296]
-------------------------------------------------------------------------------------------------------
S
---------
G
G
K
V
A
D
Y
I
P
Q
L
A
K
F
S
P
D
L
W
G
V
S
V
C
T
V
D
G
Q
R
H
S
T
G
D
T
K
V
P
F
C
L
Q
S
C
V
K
P
L
K
Y
A
I
A
V
N
D
L
G
T
E
Y
V
H
R
Y
V
G
K
E
P
S
G
L
R
F
N
---
K
L
F
L
N
E
-
D
D
K
P
H
N
P
M
V
N
A
G
A
I
V
V
T
S
L
I
--
K
Q
G
-
V
--
N
--
N
A
E
K
F
D
Y
V
M
Q
F
L
N
K
M
A
G
-
N
E
Y
V
-
G
F
S
N
A
T
F
Q
S
E
R
E
S
G
D
R
N
F
A
I
G
Y
Y
L
K
E
K
K
C
F
---
P
EG
T
-
D
M
V
G
I
L
D
F
Y
F
Q
L
C
S
I
E
V
T
C
E
S
A
S
V
M
A
A
T
L
A
N
G
G
F
C
P
I
T
G
E
R
V
L
S
P
E
A
V
R
N
T
L
S
L
M
H
S
C
G
M
Y
D
F
S
G
Q
F
A
F
H
V
G
L
P
A
K
S
G
V
A
G
G
I
L
L
V
V
P
N
V
M
----------
G
M
M
C
W
S
P
P
L
D
K
M
G
N
S
V
K
G
-----------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
62.46
34%
-104
- C6 -
4O7D
1
GLSK_HUMAN
A:
[24-296]
-------------------------------------------------------------------------------------------------------
S
---------
G
G
K
V
A
D
Y
I
P
Q
L
A
K
F
S
P
D
L
W
G
V
S
V
C
T
V
D
G
Q
R
H
S
T
G
D
T
K
V
P
F
C
L
Q
S
C
V
K
P
L
K
Y
A
I
A
V
N
D
L
G
T
E
Y
V
H
R
Y
V
G
K
E
P
S
G
L
R
F
N
---
K
L
F
L
N
E
-
D
D
K
P
H
N
P
M
V
N
A
G
A
I
V
V
T
S
L
I
--
K
Q
G
-
V
--
N
--
N
A
E
K
F
D
Y
V
M
Q
F
L
N
K
M
A
G
-
N
E
Y
V
-
G
F
S
N
A
T
F
Q
S
E
R
E
S
G
D
R
N
F
A
I
G
Y
Y
L
K
E
K
K
C
F
---
P
EG
T
-
D
M
V
G
I
L
D
F
Y
F
Q
L
C
S
I
E
V
T
C
E
S
A
S
V
M
A
A
T
L
A
N
G
G
F
C
P
I
T
G
E
R
V
L
S
P
E
A
V
R
N
T
L
S
L
M
H
S
C
G
M
Y
D
F
S
G
Q
F
A
F
H
V
G
L
P
A
K
S
G
V
A
G
G
I
L
L
V
V
P
N
V
M
----------
G
M
M
C
W
S
P
P
L
D
K
M
G
N
S
V
K
G
-----------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
61.58
34%
-103
- C6 -
3VP0
3
GLSK_HUMAN
A:
[24-296]
-------------------------------------------------------------------------------------------------------
S
---------
G
G
K
V
A
D
Y
I
P
Q
L
A
K
F
S
P
D
L
W
G
V
S
V
C
T
V
D
G
Q
R
H
S
T
G
D
T
K
V
P
F
C
L
Q
S
C
V
K
P
L
K
Y
A
I
A
V
N
D
L
G
T
E
Y
V
H
R
Y
V
G
K
E
P
S
G
L
------
K
L
F
L
N
E
-
D
D
K
P
H
N
P
M
V
N
A
G
A
I
V
V
T
S
L
I
--
K
Q
G
-
V
--
N
--
N
A
E
K
F
D
Y
V
M
Q
F
L
N
K
M
A
G
-
N
E
Y
V
-
G
F
S
N
A
T
F
Q
S
E
R
E
S
G
D
R
N
F
A
I
G
Y
Y
L
K
E
K
K
C
F
---
P
EG
T
-
D
M
V
G
I
L
D
F
Y
F
Q
L
C
S
I
E
V
T
C
E
S
A
S
V
M
A
A
T
L
A
N
G
G
F
C
P
I
T
G
E
R
V
L
S
P
E
A
V
R
N
T
L
S
L
M
H
S
C
G
M
Y
D
F
S
G
Q
F
A
F
H
V
G
L
P
A
K
S
G
V
A
G
G
I
L
L
V
V
P
N
V
M
----------
G
M
M
C
W
S
P
P
L
D
K
M
G
N
S
V
K
G
-----------------------------------------------------------------------------------------------------------