@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu30940: (2016-07-21 )
MNHSKTLLLTAAAGLMLTCGAVSSQAKHKLSDPYHFTVNAAAETEPVDTAGDAADDPAIWLDPKTPQNSKLITTNKKSGLVVYSLDGKMLHSYNTGKLNNVDIRYDFPLNGKKVDIAAASNRSEGKNTIEIYAIDGKNGTLQSMTDPDHPIATAINEVYGFTLYHSQKTGKYYAMVTGKEGEFEQYELKADKNGYISGKKVRAFKMNSQTEGMAADDEYGRLYIAEEDEAIWKFSAEPDGGSNGTVIDRADGRHLTRDIEGLTIYYAADGKGYLMASSQGNSSYAIYDRQGKNKYVADFRITDGPETDGTSDTDGIDVLGFGLGPEYPFGIFVAQDGENIDHGQKANQNFKIVPWERIADQIGFRPLANEQVDPRKLTDRSGK
Atome Classification :
(20 SA)
.........10........---------20........30........40........--50........60........70........80......--.--.90........100..--.....110.......120--------......--.130....--...140...-....150.......160.......170.......180.......190....---...200.......210.......220......----------------------------------------.-230......-.240.......250-........260.......270.......280.......290.......300.......310.-----------......320.......330.......340.......350.......360.......370.......380.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNHS
K
T
L
L
L
TAAA
G
L
M
L
T
C---------GAV
S
S
Q
AKHKLSDP
Y
H
F
T
V
NAAAETEPVDT--AGDAADD
P
A
I
W
LDPKTPQN
S
K
L
I
T
TNKKS
G
L
V
V
Y
SLDG--
K
--
M
L
H
SYNTGKL
N
N
V
D
I
R
--
Y
DFPLNG
K
K
V
D
I
A
AASNR--------SEGK
N
T
--
I
E
I
Y
A
IDG--KNGTLQSMT-DPD
H
P
I
A
T
A
I
N
E
VY
G
F
T
L
Y
H
SQKT
G
K
Y
Y
A
M
V
TGKEGE
F
E
Q
Y
E
LKADKNGYI---SG
K
K
V
R
A
F
K
MNSQTEGMAADDEY
G
R
L
Y
I
AEED----------------------------------------E-
A
I
W
K
F
SAEP-DGGSNG
T
V
I
DRAD--G
R
H
L
T
RDIE
G
L
T
I
Y
Y
AADGK
G
Y
L
M
A
SSQGNS
S
Y
A
I
Y
DRQGKN
K
Y
V
A
D
F
R
ITDGPETDGTSDT-----------DG
I
D
V
L
GFGLGPEY
P
F
G
I
F
V
AQDGENIDHGQKANQN
F
K
I
V
P
W
E
R
I
A
D
Q
IGFRPLANEQVDPRKLTDRSGK
2
PsiBlast_PDB
95.46
100%
-41
- C2 -
3AMS
12
PHYC_BACIU
A:
[2-353]
--------------------------------------
L
S
D
P
Y
H
F
T
V
N
A
A
A
E
T
E
P
V
D
T
--
A
G
D
A
A
D
D
P
A
I
W
L
D
P
K
T
P
Q
N
S
K
L
I
T
T
N
K
K
S
G
L
V
V
Y
S
L
D
G
--
K
--
M
L
H
S
Y
N
T
G
K
L
N
N
V
D
I
R
--
Y
D
F
P
L
N
G
K
K
V
D
I
A
A
A
S
N
R
--------
S
E
G
K
N
T
--
I
E
I
Y
A
I
D
G
--
K
N
G
T
L
Q
S
M
T
-
D
P
D
H
P
I
A
T
A
I
N
E
V
Y
G
F
T
L
Y
H
S
Q
K
T
G
K
Y
Y
A
M
V
T
G
K
E
G
E
F
E
Q
Y
E
L
K
A
D
K
N
G
Y
I
---
S
G
K
K
V
R
A
F
K
M
N
S
Q
T
E
G
M
A
A
D
D
E
Y
G
R
L
Y
I
A
E
E
D
----------------------------------------
E
-
A
I
W
K
F
S
A
E
P
-
D
G
G
S
N
G
T
V
I
D
R
A
D
--
G
R
H
L
T
R
D
I
E
G
L
T
I
Y
Y
A
A
D
G
K
G
Y
L
M
A
S
S
Q
G
N
S
S
Y
A
I
Y
D
R
Q
G
K
N
K
Y
V
A
D
F
R
I
T
D
G
P
E
T
D
G
T
S
D
T
-----------
D
G
I
D
V
L
G
F
G
L
G
P
E
Y
P
F
G
I
F
V
A
Q
D
G
E
N
I
D
H
G
Q
K
A
N
Q
N
F
K
I
V
P
W
E
R
I
A
D
Q
I
G
F
R
P
L
A
N
E
Q
V
D
P
R
K
L
T
D
R
S
--
1
PsiBlast_PDB
94.77
100%
-41
- C2 -
3AMR
12
PHYC_BACIU
A:
[2-353]
--------------------------------------
L
S
D
P
Y
H
F
T
V
N
A
A
A
E
T
E
P
V
D
T
--
A
G
D
A
A
D
D
P
A
I
W
L
D
P
K
T
P
Q
N
S
K
L
I
T
T
N
K
K
S
G
L
V
V
Y
S
L
D
G
--
K
--
M
L
H
S
Y
N
T
G
K
L
N
N
V
D
I
R
--
Y
D
F
P
L
N
G
K
K
V
D
I
A
A
A
S
N
R
--------
S
E
G
K
N
T
--
I
E
I
Y
A
I
D
G
--
K
N
G
T
L
Q
S
M
T
-
D
P
D
H
P
I
A
T
A
I
N
E
V
Y
G
F
T
L
Y
H
S
Q
K
T
G
K
Y
Y
A
M
V
T
G
K
E
G
E
F
E
Q
Y
E
L
K
A
D
K
N
G
Y
I
---
S
G
K
K
V
R
A
F
K
M
N
S
Q
T
E
G
M
A
A
D
D
E
Y
G
R
L
Y
I
A
E
E
D
----------------------------------------
E
-
A
I
W
K
F
S
A
E
P
-
D
G
G
S
N
G
T
V
I
D
R
A
D
--
G
R
H
L
T
R
D
I
E
G
L
T
I
Y
Y
A
A
D
G
K
G
Y
L
M
A
S
S
Q
G
N
S
S
Y
A
I
Y
D
R
Q
G
K
N
K
Y
V
A
D
F
R
I
T
D
G
P
E
T
D
G
T
S
D
T
-----------
D
G
I
D
V
L
G
F
G
L
G
P
E
Y
P
F
G
I
F
V
A
Q
D
G
E
N
I
D
H
G
Q
K
A
N
Q
N
F
K
I
V
P
W
E
R
I
A
D
Q
I
G
F
R
P
L
A
N
E
Q
V
D
P
R
K
L
T
D
R
S
--
34
Fugue
94.63
92%
-47
- C2 -
1CVM
8
PHYT_BACSD
A:
[1-353]
-------------------------------------
K
L
S
D
P
Y
H
F
T
V
N
A
A
A
E
T
E
P
V
D
T
--
A
G
D
A
A
D
D
P
A
I
W
L
D
P
K
N
P
Q
N
S
K
L
I
T
T
N
K
K
S
G
L
A
V
Y
S
L
E
G
--
K
--
M
L
H
S
Y
H
T
G
K
L
N
N
V
D
I
R
--
Y
D
F
P
L
N
G
K
K
V
D
I
A
A
A
S
N
R
--------
S
E
G
K
N
T
--
I
E
I
Y
A
I
D
G
--
K
N
G
T
L
Q
S
I
T
-
D
P
N
R
P
I
A
S
A
I
D
E
V
Y
G
F
S
L
Y
H
S
Q
K
T
G
K
Y
Y
A
M
V
T
G
K
E
G
E
F
E
Q
Y
E
L
N
A
D
K
N
G
Y
I
---
S
G
K
K
V
R
A
F
K
M
N
S
Q
T
E
G
M
A
A
D
D
E
Y
G
S
L
Y
I
A
E
E
D
----------------------------------------
E
-
A
I
W
K
F
S
A
E
P
-
D
G
G
S
N
G
T
V
I
D
R
A
D
--
G
R
H
L
T
P
D
I
E
G
L
T
I
Y
Y
A
A
D
G
K
G
Y
L
L
A
S
S
Q
G
N
S
S
Y
A
I
Y
E
R
Q
G
Q
N
K
Y
V
A
D
F
Q
I
T
D
G
P
E
T
D
G
T
S
D
T
-----------
D
G
I
D
V
L
G
F
G
L
G
P
E
Y
P
F
G
L
F
V
A
Q
N
G
E
N
I
D
H
G
Q
K
A
N
Q
N
F
K
M
V
P
W
E
R
I
A
D
K
I
G
F
H
P
Q
V
N
K
Q
V
D
P
R
K
M
T
D
R
S
--
6
PsiBlast_PDB
94.49
92%
-47
- C2 -
1CVM
8
PHYT_BACSD
A:
[1-353]
-------------------------------------
K
L
S
D
P
Y
H
F
T
V
N
A
A
A
E
T
E
P
V
D
T
--
A
G
D
A
A
D
D
P
A
I
W
L
D
P
K
N
P
Q
N
S
K
L
I
T
T
N
K
K
S
G
L
A
V
Y
S
L
E
G
--
K
--
M
L
H
S
Y
H
T
G
K
L
N
N
V
D
I
R
--
Y
D
F
P
L
N
G
K
K
V
D
I
A
A
A
S
N
R
--------
S
E
G
K
N
T
--
I
E
I
Y
A
I
D
G
--
K
N
G
T
L
Q
S
I
T
-
D
P
N
R
P
I
A
S
A
I
D
E
V
Y
G
F
S
L
Y
H
S
Q
K
T
G
K
Y
Y
A
M
V
T
G
K
E
G
E
F
E
Q
Y
E
L
N
A
D
K
N
G
Y
I
---
S
G
K
K
V
R
A
F
K
M
N
S
Q
T
E
G
M
A
A
D
D
E
Y
G
S
L
Y
I
A
E
E
D
----------------------------------------
E
-
A
I
W
K
F
S
A
E
P
-
D
G
G
S
N
G
T
V
I
D
R
A
D
--
G
R
H
L
T
P
D
I
E
G
L
T
I
Y
Y
A
A
D
G
K
G
Y
L
L
A
S
S
Q
G
N
S
S
Y
A
I
Y
E
R
Q
G
Q
N
K
Y
V
A
D
F
Q
I
T
D
G
P
E
T
D
G
T
S
D
T
-----------
D
G
I
D
V
L
G
F
G
L
G
P
E
Y
P
F
G
L
F
V
A
Q
N
G
E
N
I
D
H
G
Q
K
A
N
Q
N
F
K
M
V
P
W
E
R
I
A
D
K
I
G
F
H
P
Q
V
N
K
Q
V
D
P
R
K
M
T
D
R
S
--
13
HHSearch
94.46
100%
-39
- C2 -
3AMR
12
PHYC_BACIU
A:
[3-353]
---------------------------------------
S
D
P
Y
H
F
T
V
N
A
A
A
E
T
E
P
V
D
T
--
A
G
D
A
A
D
D
P
A
I
W
L
D
P
K
T
P
Q
N
S
K
L
I
T
T
N
K
K
S
G
L
V
V
Y
S
L
D
G
--
K
--
M
L
H
S
Y
N
T
G
K
L
N
N
V
D
I
R
--
Y
D
F
P
L
N
G
K
K
V
D
I
A
A
A
S
N
R
--------
S
E
G
K
N
T
--
I
E
I
Y
A
I
D
G
--
K
N
G
T
L
Q
S
M
T
-
D
P
D
H
P
I
A
T
A
I
N
E
V
Y
G
F
T
L
Y
H
S
Q
K
T
G
K
Y
Y
A
M
V
T
G
K
E
G
E
F
E
Q
Y
E
L
K
A
D
K
N
G
Y
I
---
S
G
K
K
V
R
A
F
K
M
N
S
Q
T
E
G
M
A
A
D
D
E
Y
G
R
L
Y
I
A
E
E
D
----------------------------------------
E
-
A
I
W
K
F
S
A
E
P
-
D
G
G
S
N
G
T
V
I
D
R
A
D
--
G
R
H
L
T
R
D
I
E
G
L
T
I
Y
Y
A
A
D
G
K
G
Y
L
M
A
S
S
Q
G
N
S
S
Y
A
I
Y
D
R
Q
G
K
N
K
Y
V
A
D
F
R
I
T
D
G
P
E
T
D
G
T
S
D
T
-----------
D
G
I
D
V
L
G
F
G
L
G
P
E
Y
P
F
G
I
F
V
A
Q
D
G
E
N
I
D
H
G
Q
K
A
N
Q
N
F
K
I
V
P
W
E
R
I
A
D
Q
I
G
F
R
P
L
A
N
E
Q
V
D
P
R
K
L
T
D
R
S
--
33
Fugue
94.38
92%
-42
- C2 -
1H6L
9
PHYT_BACSD
A:
[1-353]
-------------------------------------
K
L
S
D
P
Y
H
F
T
V
N
A
A
A
E
T
E
P
V
D
T
--
A
G
D
A
A
D
D
P
A
I
W
L
D
P
K
N
P
Q
N
S
K
L
I
T
T
N
K
K
S
G
L
A
V
Y
S
L
E
G
--
K
--
M
L
H
S
Y
H
T
G
K
L
N
N
V
D
I
R
--
Y
D
F
P
L
N
G
K
K
V
D
I
A
A
A
S
N
R
--------
S
E
G
K
N
T
--
I
E
I
Y
A
I
D
G
--
K
N
G
T
L
Q
S
I
T
-
D
P
N
R
P
I
A
S
A
I
D
E
V
Y
G
F
S
L
Y
H
S
Q
K
T
G
K
Y
Y
A
M
V
T
G
K
E
G
E
F
E
Q
Y
E
L
N
A
D
K
N
G
Y
I
---
S
G
K
K
V
R
A
F
K
M
N
S
Q
T
E
G
M
A
A
D
D
E
Y
G
S
L
Y
I
A
E
E
D
----------------------------------------
E
-
A
I
W
K
F
S
A
E
P
-
D
G
G
S
N
G
T
V
I
D
R
A
D
--
G
R
H
L
T
P
D
I
E
G
L
T
I
Y
Y
A
A
D
G
K
G
Y
L
L
A
S
S
Q
G
N
S
S
Y
A
I
Y
E
R
Q
G
Q
N
K
Y
V
A
D
F
Q
I
T
D
G
P
E
T
D
G
T
S
D
T
-----------
D
G
I
D
V
L
G
F
G
L
G
P
E
Y
P
F
G
L
F
V
A
Q
N
G
E
N
I
D
H
G
Q
K
A
N
Q
N
F
K
M
V
P
W
E
R
I
A
D
K
I
G
F
H
P
Q
V
N
K
Q
V
D
P
R
K
M
T
D
R
S
--
7
PsiBlast_PDB
94.25
92%
-42
- C2 -
1H6L
9
PHYT_BACSD
A:
[1-353]
-------------------------------------
K
L
S
D
P
Y
H
F
T
V
N
A
A
A
E
T
E
P
V
D
T
--
A
G
D
A
A
D
D
P
A
I
W
L
D
P
K
N
P
Q
N
S
K
L
I
T
T
N
K
K
S
G
L
A
V
Y
S
L
E
G
--
K
--
M
L
H
S
Y
H
T
G
K
L
N
N
V
D
I
R
--
Y
D
F
P
L
N
G
K
K
V
D
I
A
A
A
S
N
R
--------
S
E
G
K
N
T
--
I
E
I
Y
A
I
D
G
--
K
N
G
T
L
Q
S
I
T
-
D
P
N
R
P
I
A
S
A
I
D
E
V
Y
G
F
S
L
Y
H
S
Q
K
T
G
K
Y
Y
A
M
V
T
G
K
E
G
E
F
E
Q
Y
E
L
N
A
D
K
N
G
Y
I
---
S
G
K
K
V
R
A
F
K
M
N
S
Q
T
E
G
M
A
A
D
D
E
Y
G
S
L
Y
I
A
E
E
D
----------------------------------------
E
-
A
I
W
K
F
S
A
E
P
-
D
G
G
S
N
G
T
V
I
D
R
A
D
--
G
R
H
L
T
P
D
I
E
G
L
T
I
Y
Y
A
A
D
G
K
G
Y
L
L
A
S
S
Q
G
N
S
S
Y
A
I
Y
E
R
Q
G
Q
N
K
Y
V
A
D
F
Q
I
T
D
G
P
E
T
D
G
T
S
D
T
-----------
D
G
I
D
V
L
G
F
G
L
G
P
E
Y
P
F
G
L
F
V
A
Q
N
G
E
N
I
D
H
G
Q
K
A
N
Q
N
F
K
M
V
P
W
E
R
I
A
D
K
I
G
F
H
P
Q
V
N
K
Q
V
D
P
R
K
M
T
D
R
S
--
3
PsiBlast_PDB
93.85
92%
-41
- C2 -
1POO
2
PHYT_BACSD
A:
[1-353]
-------------------------------------
K
L
S
D
P
Y
H
F
T
V
N
A
A
A
E
T
E
P
V
D
T
--
A
G
D
A
A
D
D
P
A
I
W
L
D
P
K
N
P
Q
N
S
K
L
I
T
T
N
K
K
S
G
L
A
V
Y
S
L
E
G
--
K
--
M
L
H
S
Y
H
T
G
K
L
N
N
V
D
I
R
--
Y
D
F
P
L
N
G
K
K
V
D
I
A
A
A
S
N
R
--------
S
E
G
K
N
T
--
I
E
I
Y
A
I
D
G
--
K
N
G
T
L
Q
S
I
T
-
D
P
N
R
P
I
A
S
A
I
D
E
V
Y
G
F
S
L
Y
H
S
Q
K
T
G
K
Y
Y
A
M
V
T
G
K
E
G
E
F
E
Q
Y
E
L
N
A
D
K
N
G
Y
I
---
S
G
K
K
V
R
A
F
K
M
N
S
Q
T
E
G
M
A
A
D
D
E
Y
G
S
L
Y
I
A
E
E
D
----------------------------------------
E
-
A
I
W
K
F
S
A
E
P
-
D
G
G
S
N
G
T
V
I
D
R
A
D
--
G
R
H
L
T
P
D
I
E
G
L
T
I
Y
Y
A
A
D
G
K
G
Y
L
L
A
S
S
Q
G
N
S
S
Y
A
I
Y
E
R
Q
G
Q
N
K
Y
V
A
D
F
Q
I
T
D
G
P
E
T
D
G
T
S
D
T
-----------
D
G
I
D
V
L
G
F
G
L
G
P
E
Y
P
F
G
L
F
V
A
Q
D
G
E
N
I
D
H
G
Q
K
A
N
Q
N
F
K
M
V
P
W
E
R
I
A
D
K
I
G
F
H
P
Q
V
N
K
Q
V
D
P
R
K
M
T
D
R
S
--
5
PsiBlast_PDB
93.51
92%
-45
- C2 -
1QLG
5
PHYT_BACSD
A:
[1-353]
-------------------------------------
K
L
S
D
P
Y
H
F
T
V
N
A
A
A
E
T
E
P
V
D
T
--
A
G
D
A
A
D
D
P
A
I
W
L
D
P
K
N
P
Q
N
S
K
L
I
T
T
N
K
K
S
G
L
A
V
Y
S
L
E
G
--
K
--
M
L
H
S
Y
H
T
G
K
L
N
N
V
D
I
R
--
Y
D
F
P
L
N
G
K
K
V
D
I
A
A
A
S
N
R
--------
S
E
G
K
N
T
--
I
E
I
Y
A
I
D
G
--
K
N
G
T
L
Q
S
I
T
-
D
P
N
R
P
I
A
S
A
I
D
E
V
Y
G
F
S
L
Y
H
S
Q
K
T
G
K
Y
Y
A
M
V
T
G
K
E
G
E
F
E
Q
Y
E
L
N
A
D
K
N
G
Y
I
---
S
G
K
K
V
R
A
F
K
M
N
S
Q
T
E
G
M
A
A
D
D
E
Y
G
S
L
Y
I
A
E
E
D
----------------------------------------
E
-
A
I
W
K
F
S
A
E
P
-
D
G
G
S
N
G
T
V
I
D
R
A
D
--
G
R
H
L
T
P
D
I
E
G
L
T
I
Y
Y
A
A
D
G
K
G
Y
L
L
A
S
S
Q
G
N
S
S
Y
A
I
Y
E
R
Q
G
Q
N
K
Y
V
A
D
F
Q
I
T
D
G
P
E
T
D
G
T
S
D
T
-----------
D
G
I
D
V
L
G
F
G
L
G
P
E
Y
P
F
G
L
F
V
A
Q
N
G
E
N
I
D
H
G
Q
K
A
N
Q
N
F
K
M
V
P
W
E
R
I
A
D
K
I
G
F
H
P
Q
V
N
K
Q
V
D
P
R
K
M
T
D
R
S
--
4
PsiBlast_PDB
93.37
92%
-42
- C2 -
2POO
6
PHYT_BACSD
A:
[1-353]
-------------------------------------
K
L
S
D
P
Y
H
F
T
V
N
A
A
A
E
T
E
P
V
D
T
--
A
G
D
A
A
D
D
P
A
I
W
L
D
P
K
N
P
Q
N
S
K
L
I
T
T
N
K
K
S
G
L
A
V
Y
S
L
E
G
--
K
--
M
L
H
S
Y
H
T
G
K
L
N
N
V
D
I
R
--
Y
D
F
P
L
N
G
K
K
V
D
I
A
A
A
S
N
R
--------
S
E
G
K
N
T
--
I
E
I
Y
A
I
D
G
--
K
N
G
T
L
Q
S
I
T
-
D
P
N
R
P
I
A
S
A
I
D
E
V
Y
G
F
S
L
Y
H
S
Q
K
T
G
K
Y
Y
A
M
V
T
G
K
E
G
E
F
E
Q
Y
E
L
N
A
D
K
N
G
Y
I
---
S
G
K
K
V
R
A
F
K
M
N
S
Q
T
E
G
M
A
A
D
D
E
Y
G
S
L
Y
I
A
E
E
D
----------------------------------------
E
-
A
I
W
K
F
S
A
E
P
-
D
G
G
S
N
G
T
V
I
D
R
A
D
--
G
R
H
L
T
P
D
I
E
G
L
T
I
Y
Y
A
A
D
G
K
G
Y
L
L
A
S
S
Q
G
N
S
S
Y
A
I
Y
E
R
Q
G
Q
N
K
Y
V
A
D
F
Q
I
T
D
G
P
E
T
D
G
T
S
D
T
-----------
D
G
I
D
V
L
G
F
G
L
G
P
E
Y
P
F
G
L
F
V
A
Q
D
G
E
N
I
D
H
G
Q
K
A
N
Q
N
F
K
M
V
P
W
E
R
I
A
D
K
I
G
F
H
P
Q
V
N
K
Q
V
D
P
R
K
M
T
D
R
S
--
42
Fugue
34.39
10%
11
- C2 -
1IJQ
-
LDLR_HUMAN
A:
[377-692]
----
I
A
Y
L
F
F
T
N
R
H
E
V
R
K
M
---------
T
L
D
R
S
E
Y
T
S
L
I
P
N
L
----------
R
N
V
V
A
L
--
D
T
E
V
A
S
N
R
I
Y
W
S
D
L
S
---
Q
R
M
I
C
S
T
Q
L
Y
D
T
V
I
S
R
D
I
Q
A
PD
G
--
L
A
V
D
W
I
H
S
N
I
Y
W
T
D
-------------------------------
S
V
L
G
T
--
V
S
V
A
D
T
K
G
--
V
K
R
K
T
L
F
R
E
-
N
G
S
K
P
R
A
I
V
V
D
----------
P
V
H
G
F
M
Y
W
T
D
W
G
T
P
A
K
I
K
K
G
G
L
N
G
V
D
I
Y
S
L
---
V
T
E
N
I
------
Q
W
P
N
G
I
T
L
D
L
L
S
G
R
L
Y
W
V
D
S
K
----------------------------------------
L
-
H
S
I
S
S
I
D
-
V
-
N
G
G
N
R
K
T
I
L
E
D
E
K
RL
A
H
P
F
S
L
A
V
F
E
D
K
V
F
W
T
D
I
I
N
E
A
I
F
S
A
N
R
L
T
G
S
D
V
N
L
L
A
E
N
L
L
S
-
P
E
D
M
V
L
F
H
N
L
T
Q
P
R
G
V
N
W
CERTTLSNGGC
Q
Y
L
C
L
P
A
P
Q
I
N
P
H
S
P
K
F
T
C
A
C
P
D
G
M
L
L
A
R
D
M
R
S
C
L
T
----------------------------------
35
Fugue
32.91
13%
24
- C2 -
1Q7F
-
BRAT_DROME
A:
[759-1037]
-
I
K
R
Q
R
M
I
Y
H
C
K
F
G
----------------
E
F
G
V
M
E
G
Q
F
T
E
P
S
G
V
A
V
N
----------------------------
A
Q
N
D
I
I
V
A
D
T
N
N
H
R
I
Q
I
F
D
K
E
G
--
R
--
F
K
F
Q
F
G
E
C
G
K
R
D
S
Q
L
L
YP
N
R
V
A
V
V
R
N
S
G
D
I
I
V
T
E
R
S
--------
P
T
--
H
Q
--
I
Q
I
Y
N
Q
Y
G
--
Q
F
V
R
K
F
G
A
T
-
I
L
Q
H
P
R
G
V
T
V
D
N
K
G
R
I
I
V
V
E
C
---
K
V
M
R
V
I
I
F
D
Q
N
G
N
V
L
H
K
F
G
C
S
K
H
L
E
F
P
---
N
G
V
V
V
---------------
N
D
K
Q
E
I
F
I
S
D
N
R
----------------------------------------
A
H
C
V
K
V
F
N
-------
Y
E
G
Q
Y
L
R
Q
I
G
--
G
E
G
I
T
N
Y
P
I
G
V
G
I
---
N
S
N
G
E
I
L
I
A
D
N
H
N
N
F
N
L
T
I
F
T
Q
D
G
Q
L
I
S
A
L
E
S
K
V
K
H
A
Q
C
F
D
V
A
L
M
D
-----------
D
G
--------------
S
V
V
L
A
S
K
----------
D
Y
R
L
Y
I
Y
R
Y
V
Q
L
A
P
--------------------
V
G
M
29
HHSearch
31.52
18%
-62
- C2 -
1PBY
1
?
B:
[114-162]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
R
V
A
L
Y
D
A
E
T
L
----------
S
R
R
K
A
F
E
A
P
R
Q
I
T
M
L
A
W
A
R
D
G
S
K
L
Y
G
L
G
R
D
-------------------------------------------
L
H
V
M
D
P
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
29.79
9%
14
- C2 -
2QXV
-
EED_MOUSE
A:
[81-432]
F
K
C
V
N
S
L
K
E
D
H
N
Q
P
L
F
G
V
Q
F
NWHSKEGD
P
L
V
F
A
T
V
G
S
N
R
V
T
L
Y
E
C
H
S
Q
G
E
I
R
L
L
Q
S
Y
V
D
A
D
A
D
E
N
F
Y
T
C
A
W
T
Y
D
S
N
T
S
H
P
L
L
A
V
A
G
S
R
G
I
I
R
I
I
N
P
I
T
--
M
--
Q
C
I
K
H
Y
V
G
H
G
N
A
I
N
E
L
--
K
F
H
P
R
D
P
N
--
L
L
L
S
V
S
K
D
H
A
L
R
L
W
NI
Q
T
D
T
L
V
--
A
I
F
G
G
V
E
G
--
H
R
D
E
V
L
S
A
D
Y
D
L
L
G
E
K
I
M
S
C
G
M
D
H
S
L
K
L
W
R
I
-
N
S
K
R
M
M
N
A
I
K
E
S
Y
D
Y
N
F
I
S
Q
K
I
H
F
P
D
F
S
T
RDI
H
R
N
Y
V
D
C
V
R
W
L
G
D
L
I
L
S
K
S
C
E
N
A
I
V
C
W
K
P
G
K
M
----------------------------------------
E
-
D
--
D
I
D
K
I
K
-
P
S
E
S
N
V
T
I
L
G
R
F
D
--
Y
S
Q
C
D
I
W
----
Y
M
R
F
S
M
D
F
W
Q
K
M
L
A
L
G
N
Q
V
G
K
L
Y
V
W
D
L
E
V
E
D
P
H
K
A
K
C
T
T
L
T
H
H
K
C
G
A
A
------------------
I
R
Q
T
S
F
S
R
D
S
S
I
L
I
A
V
C
D
D
A
-------------
S
I
W
R
W
D
R
L
-------------------------
41
Fugue
29.04
23%
-25
- C3 -
2JTD
-
A:
[1-122]
-----------------------------------------------------
E
E
E
M
K
--
R
L
L
A
L
S
Q
E
H
K
F
--
P
T
V
P
T
K
S
E
L
A
V
E
I
L
E
K
G
Q
V
R
F
W
M
Q
A
--
E
--
K
L
S
S
-------
N
A
K
V
S
--
Y
I
F
--
N
E
K
E
I
F
E
G
P
K
Y
K
M
--------
H
I
D
R
N
T
G
I
I
E
M
F
M
----------
E
K
L
Q
-
D
E
D
E
G
-------
T
Y
T
F
Q
I
Q
D
G
K
A
T
G
H
S
T
L
V
L
I
G
D
V
Y
K
K
L
Q
K
E
A
E
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
28.50
10%
35
- C2 -
1RI6
-
6PGL_ECOLI
A:
[2-334]
-
S
L
K
Q
T
V
Y
I
A
S
P
E
S
Q
Q
I
H
V
---------
W
N
L
N
H
E
G
A
L
T
L
T
Q
V
V
D
----
V
P
G
Q
V
Q
P
M
V
V
--
S
P
D
--------------
K
R
Y
L
Y
V
G
V
R
P
E
F
R
V
L
A
Y
R
I
A
P
--
D
DG
A
L
T
F
A
A
E
S
A
L
P
G
S
L
T
H
--
I
S
T
D
H
Q
G
Q
F
V
F
V
G
S
-------------
Y
N
A
G
N
--
V
S
V
T
R
L
E
D
GL
P
V
G
V
V
D
V
V
E
-
G
L
D
G
C
H
S
A
N
I
S
-----------
P
D
N
R
T
L
W
V
P
A
L
K
Q
D
R
I
C
L
F
T
V
S
D
D
G
H
L
V
A
---
Q
D
P
A
E
V
T
T
V
E
G
A
G
P
R
H
M
V
F
H
P
N
E
Q
Y
A
Y
C
V
N
E
L
----------------------------------------
N
-
S
S
V
D
V
W
E
L
K
-
D
P
H
G
N
I
E
C
V
Q
T
L
D
MM
P
E
N
F
S
D
T
R
W
A
A
D
I
H
I
T
P
D
G
R
-
H
L
Y
A
C
D
R
T
A
S
L
I
T
V
F
S
V
--------------------
S
E
D
G
-----------
S
V
L
S
K
E
G
F
Q
P
T
E
T
Q
P
R
G
F
N
V
D
H
S
G
K
Y
L
I
A
A
G
Q
K
S
H
H
I
S
V
Y
E
I
V
G
E
Q
G
L
L
H
E
K
G
R
Y
A
V
G
Q
G
P
M
W
V
V
V
N
A
H
E
16
HHSearch
28.39
6%
-28
- C2 -
5I5M
3
?
A:
[213-346]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
F
N
V
I
D
A
E
K
----------
M
E
V
A
F
Q
V
M
V
D
G
N
L
D
N
T
D
A
D
Y
D
G
K
Y
F
F
S
T
C
Y
N
SEMGMN
L
G
E
M
I
TAE
R
D
H
V
V
V
F
S
L
E
R
C
L
A
A
L
K
A
GK
F
T
N
Y
NG
N
-
K
V
P
V
L
D
G
R
K
G
S
D
-----
L
T
R
Y
I
P
-----
V
P
K
S
P
H
G
I
N
T
A
P
---
D
G
K
Y
F
V
A
N
G
K
L
S
P
T
V
S
V
V
E
I
A
R
-------------------------------------------------------------------------------------------------------
30
HHSearch
28.11
15%
-16
- C2 -
3M0C
-
LDLR_HUMAN
C:
[558-632]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
W
P
N
G
I
T
L
D
L
L
S
G
R
L
Y
W
V
D
S
K
----------------------------------------
L
H
S
I
S
S
I
D
V
N
G
-
G
N
--
R
K
T
I
L
E
D
-----
E
K
R
L
A
H
P
F
S
L
A
V
F
-----
E
D
K
V
F
W
T
D
I
I
N
E
A
I
F
S
A
N
R
L
T
-------------------------------------------------------------------------------------------------------
18
HHSearch
25.22
15%
-15
- C2 -
1N7D
1
LDLR_HUMAN
A:
[540-614]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
W
P
N
G
I
T
L
D
L
L
S
G
R
L
Y
W
V
D
S
K
L---------------------------------------
H
-
S
I
S
S
I
D
V
N
G
-
G
N
---
R
K
T
I
L
E
D
----
E
K
R
L
A
H
P
F
S
L
A
V
F
-----
E
D
K
V
F
W
T
D
I
I
N
E
A
I
F
S
A
N
R
L
T
-------------------------------------------------------------------------------------------------------
26
HHSearch
24.91
14%
-8
- C2 -
3V64
-
LRP4_RAT
C:
[203-275]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
W
P
N
G
L
T
I
D
Y
A
G
R
R
M
Y
W
V
D
A
K
----------------------------------------
H
H
V
I
E
R
A
N
L
D
G
-
S
H
R
--
K
A
V
I
-
S
Q
------
G
L
P
H
P
F
A
I
T
V
F
-----
E
D
S
L
Y
W
T
D
W
H
T
K
S
I
N
S
A
N
K
F
T
-------------------------------------------------------------------------------------------------------