@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu37820: (2016-08-03 )
MTKVLVTGAGGQLGLELCRQLKQAGYEVIALTKKMMNIADQRSVRHSFGHYQPDIVVNSAAFTSVDQCEKELDKAYLINGIGAYYTALESTRIGAQYVHISTDYVFNGKGTQPYREDDPLDPKTIYGKSKRLGEELIRLTTKDSTIIRTSWVYGHGGSNFVETMLKLAETKQELRVVSDQIGSPTYTKDLAEAVIKLFSHPPGIYHVSNSGICSWYEFATAIMEESGLETAILSVTTEEYGNKTPRPAYSVLSHRAIEEAGIRPRHWREALREYLQERSSACD
Atome Classification :
(23 SA)
--.........10........20........---30-------..-------.-------..-...40........50--........60.......----.---70.---..-......80........90........100......-.110.--........120.......130.......140.......150..----...-.---.160...-....170.....----..180.......190.---....----.-.-200.--.------.......210..--.......220...---....------230.---.------.....240.......250-......-.-260-.-...-.-...270.....-------..280.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--M
T
K
V
L
V
TGAG
G
Q
L
G
L
E
L
C
R
Q
L
K
QAGY
E
V
I
---
A
L
-------
T
K
-------
K
-------
M
M
-
N
I
A
D
Q
R
S
V
R
H
SFGHY--QP
D
I
V
VNSAAFT
S
V
D
Q
C
----
E
---
K
-
E
---
L
D
-
K
A
Y
L
ING
I
G
A
Y
Y
T
A
L
E
STRI
G
A
Q
Y
V
H
I
S
T
D
Y
V
FNG-KG--T--QPYREDDPLDPKTIYG
K
S
K
R
L
G
E
E
L
I
R
LTTKD
S
T
I
I
R
T
S
W
V
YG----HG
G
-
S
---
N
F
V
E
T
M
L
-
K
L
A
E
T
K
Q
E
L
R
V
V
----
S
D
QIGSP
T
Y
T
K
D
L
A
E
A
---
V
I
K
L
----F-S-H--P--P------
G
I
Y
H
VSNS--G
I
--
C
S
W
Y
E
F
A
T
A
I
M
E
E---SGL
E
------
T
A
I
L
---
S
------
V
T
T
E
E
YGNKTP
R
P
A
Y
S
V
L
-
S
H
R
A
I
E
-
E
-A-G-I-R
P
R
-
H
-
W
R
E
A
L
R
E
Y
L
Q
E
-------
R
SSACD
1
PsiBlast_PDB
77.27
42%
-57
- C1 -
1VL0
2
?
A:
[14-287]
----
K
I
L
I
T
G
A
N
G
Q
L
G
R
E
I
Q
K
Q
L
K
G
K
N
V
E
V
I
---
P
T
-------
D
V
-------
Q
-------
D
L
-
D
I
T
N
V
L
A
V
N
K
F
F
N
E
K
--
K
P
N
V
V
I
N
C
A
A
H
T
A
V
D
K
C
----
E
---
E
-
Q
---
Y
D
-
L
A
Y
K
I
N
A
I
G
P
K
N
L
A
A
A
A
Y
S
V
G
A
E
I
V
Q
I
S
T
D
Y
V
F
D
G
-
E
A
--
K
--
E
P
I
T
E
F
D
E
V
N
P
Q
S
A
Y
G
K
T
K
L
E
G
E
N
F
V
K
A
L
N
P
K
Y
Y
I
V
R
T
A
W
L
Y
G
----
D
-
G
-
N
---
N
F
V
K
T
M
I
-
N
L
G
K
T
H
D
E
L
K
V
V
----
H
D
Q
V
G
T
P
T
S
T
V
D
L
A
R
V
---
V
L
K
V
----
I
-
D
-
E
--
K
--
N
Y-----
G
T
F
H
C
T
C
K
--
G
I
--
C
S
W
Y
D
F
A
V
E
I
F
R
L
---
T
G
I
D
------
V
K
V
T
---
P
------
C
T
T
E
E
F
P
R
P
A
K
R
P
K
Y
S
V
L
-
R
N
Y
M
L
E
L
T
-
T
-
G
-
D
-
I
T
R
-
E
-
W
K
E
S
L
K
E
Y
I
---------------
24
PsiBlast_CBE
75.39
41%
-61
- C1 -
3SC6
3
?
C:
[7-284]
----
R
V
I
I
T
G
A
N
G
Q
L
G
K
Q
L
Q
E
E
L
N
P
E
E
Y
D
I
Y
---
P
F
-------
D
K
-------
K
-------
L
L
-
D
I
T
N
I
S
Q
V
Q
Q
V
V
Q
E
I
--
R
P
H
I
I
I
H
C
A
A
Y
T
K
V
D
Q
A
----
E
---
K
-
E
---
R
D
-
L
A
Y
V
I
N
A
I
G
A
R
N
V
A
V
A
S
Q
L
V
G
A
K
L
V
Y
I
S
T
D
Y
V
F
Q
G
-
D
R
--
P
--
E
G
Y
D
E
F
H
N
P
A
P
I
N
I
Y
G
A
S
K
Y
A
G
E
Q
F
V
K
E
L
H
N
K
Y
F
I
V
R
T
S
W
L
Y
G
----
K
Y
G
-
N
---
N
F
V
K
T
M
I
-
R
L
G
K
E
R
E
E
I
S
V
V
----
A
D
Q
I
G
S
P
T
Y
V
A
D
L
N
V
M
---
I
N
K
L
----
I
H
T
-
S
--
L
--
Y
------
G
T
Y
H
V
S
N
T
--
G
S
--
C
S
W
F
E
F
A
K
K
I
F
S
Y
---
A
N
M
K
------
V
N
V
L
---
P
------
V
S
T
E
E
F
G
A
A
A
A
R
P
K
Y
S
I
F
-
Q
H
N
M
L
R
-
L
-
N
-
G
F
L
-
Q
M
P
-
S
-
W
E
E
G
L
E
R
F
F
I
E
-------
T
-----
22
PsiBlast_CBE
75.21
41%
-59
- C1 -
3SC6
5
?
E:
[7-285]
----
R
V
I
I
T
G
A
N
G
Q
L
G
K
Q
L
Q
E
E
L
N
P
E
E
Y
D
I
Y
---
P
F
-------
D
K
-------
K
-------
L
L
-
D
I
T
N
I
S
Q
V
Q
Q
V
V
Q
E
I
--
R
P
H
I
I
I
H
C
A
A
Y
T
K
V
D
Q
A
----
E
---
K
-
E
---
R
D
-
L
A
Y
V
I
N
A
I
G
A
R
N
V
A
V
A
S
Q
L
V
G
A
K
L
V
Y
I
S
T
D
Y
V
F
Q
G
-
D
R
--
P
--
E
G
Y
D
E
F
H
N
P
A
P
I
N
I
Y
G
A
S
K
Y
A
G
E
Q
F
V
K
E
L
H
N
K
Y
F
I
V
R
T
S
W
L
Y
G
----
K
Y
G
-
N
---
N
F
V
K
T
M
I
-
R
L
G
K
E
R
E
E
I
S
V
V
----
A
D
Q
I
G
S
P
T
Y
V
A
D
L
N
V
M
---
I
N
K
L
----
I
H
T
-
S
--
L
--
Y
------
G
T
Y
H
V
S
N
T
--
G
S
--
C
S
W
F
E
F
A
K
K
I
F
S
Y
---
A
N
M
K
------
V
N
V
L
---
P
------
V
S
T
E
E
F
---
A
A
R
P
K
Y
S
I
F
-
Q
H
N
M
L
R
-
L
-
N
-
G
F
L
-
Q
M
P
-
S
-
W
E
E
G
L
E
R
F
F
I
E
-------
T
K
----
2
PsiBlast_PDB
75.04
41%
-55
- C1 -
3SC6
3
?
A:
[7-285]
----
R
V
I
I
T
G
A
N
G
Q
L
G
K
Q
L
Q
E
E
L
N
P
E
E
Y
D
I
Y
---
P
F
-------
D
K
-------
K
-------
L
L
-
D
I
T
N
I
S
Q
V
Q
Q
V
V
Q
E
I
--
R
P
H
I
I
I
H
C
A
A
Y
T
K
V
D
Q
A
----
E
---
K
-
E
---
R
D
-
L
A
Y
V
I
N
A
I
G
A
R
N
V
A
V
A
S
Q
L
V
G
A
K
L
V
Y
I
S
T
D
Y
V
F
Q
G
-
D
R
--
P
--
E
G
Y
D
E
F
H
N
P
A
P
I
N
I
Y
G
A
S
K
Y
A
G
E
Q
F
V
K
E
L
H
N
K
Y
F
I
V
R
T
S
W
L
Y
G
----
K
Y
G
-
N
---
N
F
V
K
T
M
I
-
R
L
G
K
E
R
E
E
I
S
V
V
----
A
D
Q
I
G
S
P
T
Y
V
A
D
L
N
V
M
---
I
N
K
L
----
I
H
T
-
S
--
L
--
Y
------
G
T
Y
H
V
S
N
T
--
G
S
--
C
S
W
F
E
F
A
K
K
I
F
S
Y
---
A
N
M
K
------
V
N
V
L
---
P
------
V
S
T
E
E
F
G
A
A
A
A
R
P
K
Y
S
I
F
-
Q
H
N
M
L
R
-
L
-
N
-
G
F
L
-
Q
M
P
-
S
-
W
E
E
G
L
E
R
F
F
I
E
-------
T
K
----
23
PsiBlast_CBE
74.86
41%
-61
- C1 -
3SC6
3
?
D:
[7-284]
----
R
V
I
I
T
G
A
N
G
Q
L
G
K
Q
L
Q
E
E
L
N
P
E
E
Y
D
I
Y
---
P
F
-------
D
K
-------
K
-------
L
L
-
D
I
T
N
I
S
Q
V
Q
Q
V
V
Q
E
I
--
R
P
H
I
I
I
H
C
A
A
Y
T
K
V
D
Q
A
----
E
---
K
-
E
---
R
D
-
L
A
Y
V
I
N
A
I
G
A
R
N
V
A
V
A
S
Q
L
V
G
A
K
L
V
Y
I
S
T
D
Y
V
F
Q
G
-
D
R
--
P
--
E
G
Y
D
E
F
H
N
P
A
P
I
N
I
Y
G
A
S
K
Y
A
G
E
Q
F
V
K
E
L
H
N
K
Y
F
I
V
R
T
S
W
L
Y
G
----
K
Y
G
-
N
---
N
F
V
K
T
M
I
-
R
L
G
K
E
R
E
E
I
S
V
V
----
A
D
Q
I
G
S
P
T
Y
V
A
D
L
N
V
M
---
I
N
K
L
----
I
H
T
-
S
--
L
--
Y
------
G
T
Y
H
V
S
N
T
--
G
S
--
C
S
W
F
E
F
A
K
K
I
F
S
Y
---
A
N
M
K
------
V
N
V
L
---
P
------
V
S
T
E
E
F
G
A
A
A
A
R
P
K
Y
S
I
F
-
Q
H
N
M
L
R
-
L
-
N
-
G
F
L
-
Q
M
P
-
S
-
W
E
E
G
L
E
R
F
F
I
E
-------
T
-----
21
PsiBlast_CBE
74.54
41%
-59
- C1 -
3SC6
2
?
F:
[7-284]
----
R
V
I
I
T
G
A
N
G
Q
L
G
K
Q
L
Q
E
E
L
N
P
E
E
Y
D
I
Y
---
P
F
-------
D
K
-------
K
-------
L
L
-
D
I
T
N
I
S
Q
V
Q
Q
V
V
Q
E
I
--
R
P
H
I
I
I
H
C
A
A
Y
T
K
V
D
Q
A
----
E
---
K
-
E
---
R
D
-
L
A
Y
V
I
N
A
I
G
A
R
N
V
A
V
A
S
Q
L
V
G
A
K
L
V
Y
I
S
T
D
Y
V
F
Q
G
-
D
R
--
P
--
E
G
Y
D
E
F
H
N
P
A
P
I
N
I
Y
G
A
S
K
Y
A
G
E
Q
F
V
K
E
L
H
N
K
Y
F
I
V
R
T
S
W
L
Y
G
----
K
Y
G
-
N
---
N
F
V
K
T
M
I
-
R
L
G
K
E
R
E
E
I
S
V
V
----
A
D
Q
I
G
S
P
T
Y
V
A
D
L
N
V
M
---
I
N
K
L
----
I
H
T
-
S
--
L
--
Y
------
G
T
Y
H
V
S
N
T
--
G
S
--
C
S
W
F
E
F
A
K
K
I
F
S
Y
---
A
N
M
K
------
V
N
V
L
---
P
------
V
S
T
E
E
F
G
A
A
A
A
R
P
K
Y
S
I
F
-
Q
H
N
M
L
R
-
L
-
N
-
G
F
L
-
Q
M
P
-
S
-
W
E
E
G
L
E
R
F
F
I
E
-------
T
-----
56
HHSearch
71.51
41%
-13
- C1 -
1VL0
2
?
A:
[12-291]
--
H
M
K
I
L
I
T
G
A
N
G
Q
L
G
R
E
I
Q
K
Q
L
K
G
K
N
V
E
V
I
---
P
T
-------
D
V
-------
Q
-------
D
L
-
D
I
T
N
V
L
A
V
N
K
F
--
F
N
E
K
K
P
N
V
V
I
N
C
A
A
H
T
A
V
D
K
C
----
E
E
Q
Y
D
-
L
A
--
Y
K
I
N
A
I
G
P
K
N
L
---
A
A
A
A
Y
S
--
V
G
A
E
I
V
Q
I
S
T
D
Y
V
F
D
G
-
E
A
--
K
--
E
P
I
T
E
F
D
E
V
N
P
Q
S
A
Y
G
K
T
K
L
E
G
E
N
F
V
K
A
L
N
P
K
Y
Y
I
V
R
T
A
W
L
Y
G
----
D
G
N
-----
N
F
V
K
T
M
I
-
N
L
G
K
T
H
D
E
L
K
V
V
----
H
D
Q
V
G
T
P
T
S
T
V
D
L
A
R
V
---
V
L
K
V
----
I
-
D
-
E
K-
N
--
Y
------
G
T
F
H
C
T
C
K
--
G
I
--
C
S
W
Y
D
F
A
V
E
I
F
R
L
---
T
G
I
D
------
V
-
K
V
T
--
P
------
C
T
T
E
E
F
P
R
P
A
K
R
P
K
Y
S
V
L
-
R
N
Y
M
L
E
-
L
T
T
-
G
-
D
-
I
T
R
-
E
-
W
K
E
S
L
K
E
Y
I
D
L
-------
L
Q
----
63
HHSearch
69.35
37%
-25
- C1 -
4WPG
3
?
A:
[4-288]
--
L
E
M
I
L
I
T
G
S
N
G
Q
L
G
T
E
L
R
Y
L
L
D
E
R
G
V
D
Y
V
---
A
V
-------
D
V
-------
A
-------
E
M
-
D
I
T
N
E
D
K
V
E
A
V
--
F
A
Q
V
K
P
T
L
V
Y
H
C
A
A
Y
T
A
V
D
A
A
E
DEG
K
---
A
-
L
N
--
E
A
I
N
V
T
G
S
E
N
I
---
A
K
A
C
G
K
--
Y
G
A
T
L
V
Y
I
S
T
D
Y
V
F
D
G
-
N
K
PV
G
--
Q
E
W
V
E
T
D
H
P
D
P
K
T
E
Y
G
R
T
K
R
L
G
E
L
A
V
E
R
Y
A
E
H
F
Y
I
I
R
T
A
W
V
F
G
----
N
Y
G
-
K
---
N
F
V
F
T
M
E
-
Q
L
A
E
N
H
S
R
L
T
V
V
----
N
D
Q
H
G
R
P
T
W
T
R
T
L
A
E
F
---
M
C
Y
L
----
T
-
E
-
N
QK
A
--
F
------
G
Y
Y
H
L
S
N
D
AK
E
D
--
T
T
W
Y
D
F
A
K
E
I
L
K
D
---
K
A
V
E
------
V
--
V
---
P
------
V
D
S
S
A
F
P
A
K
A
K
R
P
L
N
S
T
M
-
N
L
D
K
A
K
-
A
-
T
-
G
-
F
-
V
I
P
-
T
-
W
Q
E
A
L
K
A
F
Y
Q
Q
-------
G
L
K
---
55
HHSearch
68.39
39%
-22
- C1 -
3SC6
3
?
A:
[5-285]
--
K
E
R
V
I
I
T
G
A
N
G
Q
L
G
K
Q
L
Q
E
E
L
N
P
E
E
Y
D
I
Y
---
P
F
-------
D
K
-------
K
-------
L
L
-
D
I
T
N
I
S
Q
V
Q
Q
V
--
V
Q
E
I
R
P
H
I
I
I
H
C
A
A
Y
T
K
V
D
Q
A
----
E
KE-
R
D
L
A
--
Y
V
I
N
A
I
G
A
R
N
V
---
A
V
A
S
Q
L
--
V
G
A
K
L
V
Y
I
S
T
D
Y
V
F
Q
G
-
D
R
--
P
--
E
G
Y
D
E
F
H
N
P
A
P
I
N
I
Y
G
A
S
K
Y
A
G
E
Q
F
V
K
E
L
H
N
K
Y
F
I
V
R
T
S
W
L
Y
G
----
K
Y
G
-
N
---
N
F
V
K
T
M
I
-
R
L
G
K
E
R
E
E
I
S
V
V
----
A
D
Q
I
G
S
P
T
Y
V
A
D
L
N
V
M
---
I
N
K
L
----
I
-
H
-
T
S-
L
--
Y
------
G
T
Y
H
V
S
N
T
--
G
S
--
C
S
W
F
E
F
A
K
K
I
F
S
Y
---
A
N
M
K
------
V
N
V
L
---
P
------
V
S
T
E
E
F
G
A
A
A
A
R
P
K
Y
S
I
F
-
Q
-
H
N
M
L
-
R
L
N
-
G
-
F
L
Q
M
P
-
S
-
W
E
E
G
L
E
R
F
F
I
E
-------
T
K
----
3
PsiBlast_PDB
68.29
37%
-3
- C1 -
4WPG
3
?
A:
[7-285]
-----
I
L
I
T
G
S
N
G
Q
L
G
T
E
L
R
Y
L
L
D
E
R
G
V
D
Y
V
---
A
V
-------
D
V
-------
A
-------
E
M
-
D
I
T
N
E
D
K
V
E
A
V
F
A
Q
V
--
K
P
T
L
V
Y
H
C
A
A
Y
T
A
V
D
A
A
----
E
---
D
-
E
G
K
A
L
N
-
E
A
--
I
N
V
T
G
S
E
N
I
A
K
A
C
G
K
Y
G
A
T
L
V
Y
I
S
T
D
Y
V
F
D
G
-
N
K
--
P
VG
Q
E
W
V
E
T
D
H
P
D
P
K
T
E
Y
G
R
T
K
R
L
G
E
L
A
V
E
R
Y
A
E
H
F
Y
I
I
R
T
A
W
V
F
G
----
N
Y
G
-
K
---
N
F
V
F
T
M
E
-
Q
L
A
E
N
H
S
R
L
T
V
V
----
N
D
Q
H
G
R
P
T
W
T
R
T
L
A
E
F
---
M
C
Y
L
----
T
-
E
-
N
--
Q
--
K
A
F
----
G
Y
Y
H
L
S
N
D
--
A
K
ED
T
T
W
Y
D
F
A
K
E
I
L
K
D
---
K
A
V
E
--------
V
V
---
P
------
V
D
S
S
A
F
P
A
K
A
K
R
P
L
N
S
T
M
-
N
L
D
K
A
K
-
A
-
T
-
G
-
F
-
V
I
P
-
T
-
W
Q
E
A
L
K
A
F
Y
Q
Q
-------------
46
Fugue
62.29
32%
3
- C1 -
1N2S
2
RMLD_SALTY
A:
[1-298]
---
M
N
I
L
L
F
G
K
T
G
Q
V
G
W
E
L
Q
R
S
L
A
P
V
G
N
L
I
A
L
D
V
H
S
-------
K
E
-------
F
-------
C
G
-
D
F
S
N
P
K
G
V
A
E
T
V
R
K
L
--
R
P
D
V
I
V
N
A
A
A
H
T
A
V
D
K
A
----
E
---
S
-
E
---
P
E
-
L
A
Q
L
L
N
A
T
S
V
E
A
I
A
K
A
A
N
E
T
G
A
W
V
V
H
Y
S
T
D
Y
V
F
P
G
-
T
G
--
D
--
I
P
W
Q
E
T
D
A
T
S
P
L
N
V
Y
G
K
T
K
L
A
G
E
K
A
L
Q
D
N
C
P
K
H
L
I
F
R
T
S
W
V
Y
A
----
G
K
G
-
N
---
N
F
A
K
T
M
L
-
R
L
A
K
E
R
Q
T
L
S
V
I
----
N
D
Q
Y
G
A
P
T
G
A
E
L
L
A
D
C
---
T
A
H
A
----
I
-
R
-
V
--
A
--
L
N
K
PEV
A
G
L
Y
H
L
V
A
G
--
G
T
--
T
T
W
H
D
Y
A
A
L
V
F
D
E
---
A
R
K
A
GITLAL
T
E
L
N
---
A
------
V
P
T
S
A
Y
P
T
P
A
S
R
P
G
N
S
R
L
-
N
T
E
K
F
Q
-
R
-
N
F
D
-
L
-
I
L
P
-
Q
-
W
E
L
G
V
K
R
M
L
T
E
-------
M
F
T
T
T
T
11
PsiBlast_PDB
61.46
28%
5
- C1 -
4KTT
-
MAT2B_HUMAN
E:
[23-312]
----
R
V
L
V
T
G
A
T
G
L
L
G
R
A
V
H
K
E
F
Q
Q
N
N
W
H
A
V
---
G
C
-------
G
F
-------
R
RARPK
F
E
Q
V
-
N
L
L
D
S
N
A
V
H
H
I
I
H
D
F
--
Q
P
H
V
I
V
H
C
A
A
E
R
R
P
D
V
V
----
E
---
N
-
Q
---
P
D
-
A
A
S
Q
L
N
V
D
A
S
G
N
L
A
K
E
A
A
A
V
G
A
F
L
I
Y
I
S
S
D
Y
V
F
D
G
-
T
N
--
P
---
P
Y
R
E
E
D
I
P
A
P
L
N
L
Y
G
K
T
K
L
D
G
E
K
A
V
L
E
N
N
L
G
A
A
V
L
R
I
P
I
L
Y
G
----
E
V
E
-
K
LEE
S
A
V
T
V
M
F
D
K
V
Q
F
S
N
K
S
A
N
M
D
----
H
W
Q
Q
R
F
P
T
H
V
K
D
V
A
T
V
---
C
R
Q
L
A
E
K
R
M
-
L
-
D
--
P
SI
K
------
G
T
F
H
W
S
G
N
--
E
Q
--
M
T
K
Y
E
M
A
C
A
I
A
D
A
---
F
N
L
P
------
S
S
H
L
---
R
------
P
I
T
D
S
P
V
L
--
Q
R
P
R
N
A
Q
L
-
D
C
S
K
L
E
-
T
-
L
-
G
-
I
-
G
Q
R
T
P
-
F
R
I
G
I
K
E
S
L
---------------
12
PsiBlast_PDB
61.15
28%
9
- C1 -
4KTV
1
MAT2B_HUMAN
E:
[23-312]
----
R
V
L
V
T
G
A
T
G
L
L
G
R
A
V
H
K
E
F
Q
Q
N
N
W
H
A
V
---
G
C
-------
G
F
-------
R
RARPK
F
E
Q
V
-
N
L
L
D
S
N
A
V
H
H
I
I
H
D
F
--
Q
P
H
V
I
V
H
C
A
A
E
R
R
P
D
V
V
----
E
---
N
-
Q
---
P
D
-
A
A
S
Q
L
N
V
D
A
S
G
N
L
A
K
E
A
A
A
V
G
A
F
L
I
Y
I
S
S
D
Y
V
F
D
G
-
T
N
--
P
---
P
Y
R
E
E
D
I
P
A
P
L
N
L
Y
G
K
T
K
L
D
G
E
K
A
V
L
E
N
N
L
G
A
A
V
L
R
I
P
I
L
Y
G
----
E
V
E
-
K
L
E
E
S
A
V
T
V
M
F
D
K
V
Q
F
S
N
K
S
A
N
M
D
----
H
W
Q
Q
R
F
P
T
H
V
K
D
V
A
T
V
---
C
R
Q
L
A
E
K
R
M
-
L
-
D
--
P
S
I
K
------
G
T
F
H
W
S
G
N
--
E
Q
--
M
T
K
Y
E
M
A
C
A
I
A
D
A
---
F
N
L
P
------
S
S
H
L
---
R
------
P
I
T
D
S
P
V
L
G
A
Q
R
P
R
N
A
Q
L
-
D
C
S
K
L
E
-
T
-
L
-
G
-
I
-
G
Q
R
T
P
-
F
R
I
G
I
K
E
S
L
---------------
10
PsiBlast_PDB
61.06
28%
8
- C1 -
4NDN
2
MAT2B_HUMAN
E:
[19-308]
----
R
V
L
V
T
G
A
T
G
L
L
G
R
A
V
H
K
E
F
Q
Q
N
N
W
H
A
V
---
G
C
-------
G
F
-------
R
RARPK
F
E
Q
V
-
N
L
L
D
S
N
A
V
H
H
I
I
H
D
F
--
Q
P
H
V
I
V
H
C
A
A
E
R
R
P
D
V
V
----
E
---
N
-
Q
---
P
D
-
A
A
S
Q
L
N
V
D
A
S
G
N
L
A
K
E
A
A
A
V
G
A
F
L
I
Y
I
S
S
D
Y
V
F
D
G
-
T
N
--
P
---
P
Y
R
E
E
D
I
P
A
P
L
N
L
Y
G
K
T
K
L
D
G
E
K
A
V
L
E
N
N
L
G
A
A
V
L
R
I
P
I
L
Y
G
----
E
V
E
-
K
L
E
E
S
A
V
T
V
M
F
D
K
V
Q
F
S
N
K
S
A
N
M
D
----
H
W
Q
Q
R
F
P
T
H
V
K
D
V
A
T
V
---
C
R
Q
L
A
EKR
M
-
L
-
D
--
P
S
I
K
------
G
T
F
H
W
S
G
N
--
E
Q
--
M
T
K
Y
E
M
A
C
A
I
A
D
A
---
F
N
L
P
------
S
S
H
L
---
R
------
P
I
T
D
S
P
V
L
G
A
Q
R
P
R
N
A
Q
L
-
D
C
S
K
L
E
-
T
-
L
-
G
-
I
-
G
Q
R
T
P
-
F
R
I
G
I
K
E
S
L
---------------
4
PsiBlast_PDB
59.80
35%
-13
- C1 -
1KBZ
-
RMLD_SALTY
A:
[2-267]
----
N
I
L
L
F
G
K
T
G
Q
V
G
W
E
L
Q
R
S
L
A
P
V
G
-
N
L
I
---
A
L
D
VH----
S
K
-------
E
-------
F
C
G
D
F
S
N
P
K
G
V
A
E
T
V
R
K
L
--
R
P
D
V
I
V
N
A
A
A
H
T
A
V
D
K
A
----
E
---
S
-
E
---
P
E
-
L
A
Q
L
L
N
A
T
S
V
E
A
I
A
K
A
A
N
E
T
G
A
W
V
V
H
Y
S
T
D
Y
V
F
P
G
-
T
G
--
D
--
I
P
W
Q
E
T
D
A
T
S
P
L
N
V
Y
G
K
T
K
L
A
G
E
K
A
L
Q
D
N
C
P
K
H
L
I
F
R
T
S
W
V
Y
A
----
G
K
G
-
N
---
N
F
A
K
T
M
L
-
R
L
A
K
E
R
Q
T
L
S
V
I
----
N
D
Q
Y
G
A
P
T
G
A
E
L
L
A
D
C
T
A
H
A
I
R
V
----
A
-
L
-
N
--
K
--
P
EV
A
---
G
L
Y
H
L
V
A
G
--
G
T
--
T
T
W
H
D
Y
A
A
L
V
F
D
E
A
R
K
A
G
I
T
------
L
A
L
T
E
L
N
A
------
V
P
T
S
A
Y
P
T
P
A
S
R
P
G
N
S
R
L
-
N
--------------------------------------------
6
PsiBlast_PDB
59.66
35%
-11
- C1 -
1KC3
2
RMLD_SALTY
A:
[2-267]
----
N
I
L
L
F
G
K
T
G
Q
V
G
W
E
L
Q
R
S
L
A
P
V
G
-
N
L
I
---
A
L
D
VH----
S
K
-------
E
-------
F
C
G
D
F
S
N
P
K
G
V
A
E
T
V
R
K
L
--
R
P
D
V
I
V
N
A
A
A
H
T
A
V
D
K
A
----
E
---
S
-
E
---
P
E
-
L
A
Q
L
L
N
A
T
S
V
E
A
I
A
K
A
A
N
E
T
G
A
W
V
V
H
Y
S
T
D
Y
V
F
P
G
-
T
G
--
D
--
I
P
W
Q
E
T
D
A
T
S
P
L
N
V
Y
G
K
T
K
L
A
G
E
K
A
L
Q
D
N
C
P
K
H
L
I
F
R
T
S
W
V
Y
A
----
G
K
G
-
N
---
N
F
A
K
T
M
L
-
R
L
A
K
E
R
Q
T
L
S
V
I
----
N
D
Q
Y
G
A
P
T
G
A
E
L
L
A
D
C
T
A
H
A
I
R
V
----
A
-
L
-
N
--
K
--
P
EVA---
G
L
Y
H
L
V
A
G
--
G
T
--
T
T
W
H
D
Y
A
A
L
V
F
D
E
A
R
K
A
G
I
T
------
L
A
L
T
E
L
N
A
------
V
P
T
S
A
Y
P
T
P
A
S
R
P
G
N
S
R
L
-
N
--------------------------------------------
9
PsiBlast_PDB
58.75
28%
10
- C1 -
2YDX
7
MAT2B_HUMAN
A:
[4-293]
----
R
V
L
V
T
G
A
T
G
L
L
G
R
A
V
H
K
E
F
Q
Q
N
N
W
H
A
V
---
G
C
-------
G
F
-------
R
RARPK
F
E
Q
V
-
N
L
L
D
S
N
A
V
H
H
I
I
H
D
F
--
Q
P
H
V
I
V
H
C
A
A
E
R
R
P
D
V
V
----
E
---
N
-
Q
---
P
D
-
A
A
S
Q
L
N
V
D
A
S
G
N
L
A
K
E
A
A
A
V
G
A
F
L
I
Y
I
S
S
D
Y
V
F
D
G
-
T
N
--
P
---
P
Y
R
E
E
D
I
P
A
P
L
N
L
Y
G
K
T
K
L
D
G
E
K
A
V
L
E
N
N
L
G
A
A
V
L
R
I
P
I
L
Y
G
----
E
V
E
-
K
LEE
S
A
V
T
V
M
F
D
K
V
Q
F
S
N
K
S
A
N
M
D
----
H
W
Q
Q
R
F
P
T
H
V
K
D
V
A
T
V
---
C
R
Q
L
A
E
K
R
M
-
L
-
D
--
P
SI
K
------
G
T
F
H
W
S
G
N
--
E
Q
--
M
T
K
Y
E
M
A
C
A
I
A
D
A
---
F
N
L
P
------
S
S
H
L
---
R
------
P
I
T
D
S
P
V
L
G
A
Q
R
P
R
N
A
Q
L
-
D
C
S
K
L
E
-
T
-
L
-
G
-
I
-
G
Q
R
T
P
-
F
R
I
G
I
K
E
S
L
---------------
7
PsiBlast_PDB
58.56
35%
-13
- C1 -
1N2S
1
RMLD_SALTY
A:
[2-267]
----
N
I
L
L
F
G
K
T
G
Q
V
G
W
E
L
Q
R
S
L
A
P
V
G
-
N
L
I
---
A
L
D
VH----
S
K
-------
E
-------
F
C
G
D
F
S
N
P
K
G
V
A
E
T
V
R
K
L
--
R
P
D
V
I
V
N
A
A
A
H
T
A
V
D
K
A
----
E
---
S
-
E
---
P
E
-
L
A
Q
L
L
N
A
T
S
V
E
A
I
A
K
A
A
N
E
T
G
A
W
V
V
H
Y
S
T
D
Y
V
F
P
G
-
T
G
--
D
--
I
P
W
Q
E
T
D
A
T
S
P
L
N
V
Y
G
K
T
K
L
A
G
E
K
A
L
Q
D
N
C
P
K
H
L
I
F
R
T
S
W
V
Y
A
----
G
K
G
-
N
---
N
F
A
K
T
M
L
-
R
L
A
K
E
R
Q
T
L
S
V
I
----
N
D
Q
Y
G
A
P
T
G
A
E
L
L
A
D
C
T
A
H
A
I
R
V
----
A
-
L
-
N
--
K
--
P
EV
A
---
G
L
Y
H
L
V
A
G
--
G
T
--
T
T
W
H
D
Y
A
A
L
V
F
D
E
A
R
K
A
G
I
T
------
L
A
L
T
E
L
N
A
------
V
P
T
S
A
Y
P
T
P
A
S
R
P
G
N
S
R
L
-
N
--------------------------------------------
47
Fugue
58.35
28%
25
- C1 -
4NDN
1
MAT2B_HUMAN
F:
[15-323]
IP
N
R
R
V
L
V
T
G
A
T
G
L
L
G
R
A
V
H
K
E
F
Q
Q
N
N
W
H
A
V
---
G
C
GFRRARP
K
F
-------
E
-------
Q
V
-
N
L
L
D
S
N
A
V
H
H
I
I
H
D
F
--
Q
P
H
V
I
V
H
C
A
A
E
R
R
------------
P
-
D
---
V
D
-
A
A
S
Q
L
N
V
D
A
S
G
N
L
A
K
E
A
A
A
V
G
A
F
L
I
Y
I
S
S
D
Y
V
F
D
G
-
T
N
--
P
---
P
Y
R
E
E
D
I
P
A
P
L
N
L
Y
G
K
T
K
L
D
G
E
K
A
V
L
E
N
N
L
G
A
A
V
L
R
I
P
I
L
Y
G
EVEK
L
E
E
-
S
---
A
V
T
V
M
F
D
-
K
V
Q
F
S
N
K
S
A
N
M
D
----
H
W
Q
Q
R
F
P
T
H
V
K
D
V
A
T
V
---
C
R
Q
L
----
A
-
E
-
K
--
R
--
M
LDPSIK
G
T
F
H
W
S
G
N
--
E
Q
--
M
T
K
Y
E
M
A
C
A
I
A
D
A
---
F
N
L
P
------
S
S
H
L
---
R
------
P
I
T
D
S
P
V
L
G
A
Q
R
P
R
N
A
Q
L
-
D
C
S
K
L
E
-
T
-
L
-
G
-
I
-
G
Q
R
-
T
P
F
R
I
G
I
K
E
S
L
W
P
FLIDKRW
R
Q
T
V
F
H
68
HHSearch
58.22
32%
-8
- C1 -
1N2S
2
RMLD_SALTY
A:
[1-296]
---
M
N
I
L
L
F
G
K
T
G
Q
V
G
W
E
L
Q
R
S
L
A
P
V
G
N
-
L
I
---
A
L
-------
D
V
-------
H
SKEF---
C
G
-
D
F
S
N
P
K
G
V
A
E
T
--
V
R
K
L
R
P
D
V
I
V
N
A
A
A
H
T
A
V
D
K
A
----
E
S
E
P
E
-
L
A
--
Q
L
L
N
A
T
S
V
E
A
I
---
A
K
A
A
N
E
--
T
G
A
W
V
V
H
Y
S
T
D
Y
V
F
P
G
-
T
G
--
D
--
I
P
W
Q
E
T
D
A
T
S
P
L
N
V
Y
G
K
T
K
L
A
G
E
K
A
L
Q
D
N
C
P
K
H
L
I
F
R
T
S
W
V
Y
A
----
G
K
G
-
N
---
N
F
A
K
T
M
L
-
R
L
A
K
E
R
Q
T
L
S
V
I
ND
Q
Y
G
A
P
T
G
A
E
L
L
A
D
C
T
A
H
A
---
I
R
V
A
----
L
-
N
-
K
PE
V
--
A
------
G
L
Y
H
L
V
A
G
--
G
T
--
T
T
W
H
D
Y
A
A
L
V
F
D
E
---
A
R
K
A
------
G
I
T
L
---
A
LT
E
L
N
A
V
P
T
S
A
Y
P
T
P
A
S
R
P
G
N
S
R
L
-
N
T
E
K
F
Q
-
R
N
F
-
D
-
L
-
I
L
P
-
Q
-
W
E
L
G
V
K
R
M
L
T
E
-------
M
F
T
T
--
5
PsiBlast_PDB
57.92
35%
-12
- C1 -
1KC1
3
RMLD_SALTY
A:
[2-267]
----
N
I
L
L
F
G
K
T
G
Q
V
G
W
E
L
Q
R
S
L
A
P
V
G
-
N
L
I
---
A
L
DVH----
S
K
-------
E
-------
F
C
G
D
F
S
N
P
K
G
V
A
E
T
V
R
K
L
--
R
P
D
V
I
V
N
A
A
A
H
T
A
V
D
K
A
----
E
---
S
-
E
---
P
E
-
L
A
Q
L
L
N
A
T
S
V
E
A
I
A
K
A
A
N
E
T
G
A
W
V
V
H
Y
S
T
D
Y
V
F
P
G
-
T
G
--
D
--
I
P
W
Q
E
T
D
A
T
S
P
L
N
V
Y
G
K
T
K
L
A
G
E
K
A
L
Q
D
N
C
P
K
H
L
I
F
R
T
S
W
V
Y
A
----
G
K
G
-
N
---
N
F
A
K
T
M
L
-
R
L
A
K
E
R
Q
T
L
S
V
I
----
N
D
Q
Y
G
A
P
T
G
A
E
L
L
A
D
C
T
A
H
A
I
R
V
----
A
-
L
-
N
--
K
--
P
EVA---
G
L
Y
H
L
V
A
G
--
G
T
--
T
T
W
H
D
Y
A
A
L
V
F
D
E
A
R
K
A
G
I
T
------
L
A
L
T
E
L
N
A
------
V
P
T
S
A
Y
P
T
P
A
S
R
P
G
N
S
R
L
-
N
--------------------------------------------
45
Fugue
54.18
32%
25
* C1 *
2GGS
1
?
A:
[1-273]
---
M
R
T
L
I
T
G
A
S
G
Q
L
G
I
E
L
S
R
L
L
S
E
R
H
-
E
V
I
---
K
V
-------
Y
N
SSEIQG
G
Y
-------
K
L
-
D
L
T
D
F
P
R
L
E
D
F
I
I
K
K
--
R
P
D
V
I
I
N
A
A
A
M
T
D
V
D
K
C
----
E
---
I
-
E
---
K
E
-
K
A
Y
K
I
N
A
E
A
V
R
H
I
V
R
A
G
K
V
I
D
S
Y
I
V
H
I
S
T
D
Y
V
F
D
G
-
E
K
--
G
---
N
Y
K
E
E
D
I
P
N
P
I
N
Y
Y
G
L
S
K
L
L
G
E
T
F
A
L
--
Q
D
D
S
L
I
I
R
T
S
G
I
F
R
------
N
-
K
---
G
F
P
I
Y
V
Y
-
K
T
L
K
E
G
K
T
V
F
A
F
-----
K
G
Y
Y
S
P
I
S
A
R
K
L
A
S
A
---
I
L
E
L
----
L
-
E
L
R
--
K
--
T
------
G
I
I
H
V
A
G
E
--
R
---
I
S
R
F
E
L
A
L
K
I
K
E
K
---
F
N
L
P
------
G
E
V
K
---
E
------
V
D
E
V
-
R
G
W
I
A
K
R
P
Y
D
S
S
L
-
D
S
S
R
A
R
-
K
-
I
L
S
-
T
-
D
F
Y
-
T
-
L
D
L
D
G
M
V
V
----------------
8
PsiBlast_PDB
51.54
35%
10
- C1 -
2GGS
1
?
A:
[2-255]
----
R
T
L
I
T
G
A
S
G
Q
L
G
I
E
L
S
R
L
L
S
E
R
-
H
E
V
I
---
K
V
-------
Y
N
-------
S
SEIQG
G
Y
K
L
-
D
L
T
D
F
P
R
L
E
D
F
I
I
K
K
--
R
P
D
V
I
I
N
A
A
A
M
T
D
V
D
K
C
----
E
---
I
-
E
---
K
E
-
K
A
Y
K
I
N
A
E
A
V
R
H
I
V
R
A
G
K
V
I
D
S
Y
I
V
H
I
S
T
D
Y
V
F
D
G
E
K
G
--
N
----
Y
K
E
E
D
I
P
N
P
I
N
Y
Y
G
L
S
K
L
L
G
E
T
F
--
A
L
Q
D
D
S
L
I
I
R
T
S
G
I
F
R
----
N
K
G
F
P
---
I
Y
V
Y
K
T
L
-
K
E
G
K
T
V
F
A
F
K
--------
G
Y
Y
S
P
I
S
A
R
K
L
A
S
A
---
I
L
E
L
----
L
-
E
L
R
--
K
--
T
------
G
I
I
H
V
A
G
E
--
R
I
---
S
R
F
E
L
A
L
K
I
K
E
K
---
F
N
L
P
------
G
E
V
K
---
E
------
V
-
D
E
V
R
G
W
I
A
K
R
P
Y
D
S
S
L
D
S
S
R
A
-----------------------------------------