@TOME V2.3
(Nov 2016)

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Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : BTK_HUMAN: (2015-10-04 )
MAAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILENRNGSLKPGSSHRKTKKPLPPTPEEDQILKKPLPPEPAAAPVSTSELKKVVALYDYMPMNANDLQLRKGDEYFILEESNLPWWRARDKNGQEGYIPSNYVTEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKAGKYTVSVFAKSTGDPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEES

Atome Classification :

(100 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240...-..-..250...-.-.-..260.......270.......280.......290-....-...-300.......-310.......--320.......330.......340.......350.......360.......370.......380......--------------.390.--........400....-...410.......420---.------.--------.-----....430....--..---.--440.......450-.-......460.....-..470.......480.......-490-------------.------.--------..-.....500.......510.......520.......530.---......540.......--550......-...560.......570.......580.......590.......600-.-......610.......620.......630.......640.......650.......
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MAAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEKITCVETVVPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEELRKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILENRNGSLKPGSSHRKTKKPLPPTPEEDQILKKPLPPEPAAAPVSTSELKKVVALYDYMPMNANDLQLRKGDEYFILE-ES-NLPWWRAR-D-K-NGQEGYIPSNYVTEAEDSIEMYEWYSKHMTRSQAE-QLLK-QEG-KEGGFIVRDS-SKAGKYTVSV--FAKSTGDPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTA--------------GL--G--YGSWEIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREM-R---------------H------R--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEES
5 PsiBlast_PDB 84.1699%-125 - C1 -3GEN A:[16-282] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YGSWEIDPKDLTFLK-ELG---FGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREM-R---------------H------R--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
18 PsiBlast_PDB 83.5699%-133 - C1 -3OCT A:[3-265] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SWEIDPKDLTFLK-ELG--QFGVVKYGKWR---G------Q--------Y-----DVAIKMIK-----MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREM-R---------------H------R--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSR-------------------FPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMD---
24 PsiBlast_CBE 83.46100%-118 - C1 -4YHF B:[9-277] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L--G--YGSWEIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREM-R---------------H------R--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
11 PsiBlast_PDB 83.4599%-133 - C1 -3PJ1 A:[6-274] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G--YGSWEIDPKDLTFLK-ELGT---GVVKYGKWR---G------Q--------Y-----DVAIKMI-------S---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ---IFIITEYMANGCLLNYLREM-R-------------------------------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGL---------------------FPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEES
8 PsiBlast_PDB 82.9999%-123 - C1 -3PIX A:[6-273] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G--YGSWEIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREM-R---------------H------R--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
14 PsiBlast_PDB 82.98100%-120 - C1 -4ZLY A:[1-270] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GL--G--YGSWEIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREM-R---------------H------R--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
12 PsiBlast_PDB 82.9599%-131 - C1 -3PJ2 A:[6-274] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G--YGSWEIDPKDLTFLK-ELGT---GVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREM-R---------------H------R--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDF-----------------------FPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEES
13 PsiBlast_PDB 82.8499%-129 - C1 -3PJ3 A:[6-274] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G--YGSWEIDPKDLTFLK-ELGT---GVVKYGKWR---G------Q--------Y-----DVAIKMI--------------DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREM-R---------------H------R--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDF------------------------PVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEES
10 PsiBlast_PDB 82.6799%-127 - C1 -3PIZ A:[6-274] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G--YGSWEIDPKDLTFLK-ELGT---GVVKYGKWR---G------Q--------Y-----DVAIKMI-------S---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREM-R---------------H------R--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGL---------------------FPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEES
22 PsiBlast_CBE 82.6698%-121 - C1 -4RFZ A:[20-282] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREA-R---------------H------A--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
7 PsiBlast_PDB 82.5299%-129 - C1 -3K54 A:[16-282] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YGSWEIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIK--------------EFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREM-R---------------H------R--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFG----------------------FPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
21 PsiBlast_CBE 82.4498%-122 - C1 -4RG0 A:[20-282] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREA-R---------------H------A--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
3 PsiBlast_PDB 82.2398%-122 - C1 -4OTQ A:[20-282] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREA-R---------------H------A--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
15 PsiBlast_PDB 82.16100%-120 - C1 -4ZLZ A:[1-270] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GL--G--YGSWEIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREM-R---------------H------R--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
114 HHSearch 82.0539% -94 - C1 -2H8H SRC_HUMAN A:[87-523] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TFVALYDYESRTETDLSFKKGERLQIVN-NT-EGDWWLAH-S-LSTGQTGYIPSNYVAP-SDSIQAEEWYFGKITRRESE-RLLLNAEN-PRGTFLVRESETTKGAYCLSV--SDFD-NAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT---SKPQTQ--------------GL--A--KDAWEIPRESLRLEV-KLGQGCFGEVWMGTWN---G------T--------T-----RVAIKTLKPGT--MS---P--EAFLQEAQVMKKL-R-HEKLVQLYAVVS-E-EPIYIVTEYMSKGSLLDFLKGETG---------------K------Y--------LR-LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENL---VCKVADFGLARLIEDN--E--YTARQG-AKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMV-N-REVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTE
6 PsiBlast_PDB 82.0299%-117 - C1 -4Z3V A:[13-283] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GL--G--YGSWEIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREM-R---------------H------R--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEES
9 PsiBlast_PDB 82.0099%-118 - C1 -3PIY A:[6-273] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G--YGSWEIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMI-----------E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREM-R---------------H------R--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
117 HHSearch 81.9642% -95 - C1 -1OPK ABL1_MOUSE A:[44-480] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLFVALYDFVASGDNTLSITKGEKLRVLG-YNHNGEWCEAQ-T-K-NG-QGWVPSNYITPV-NSLEKHSWYHGPVSRNAAE-YLLS-S-G-INGSFLVRESESSPGQRSISL--RY------EGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKR--NKPTIY--------------GV--SPNYDKWEMERTDITMKH-KLGGGQYGEVYEGVWK---KY-----S--------L-----TVAVKTLKEDT--ME---V--EEFLKEAAVMKEI-K-HPNLVQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNR---------------Q------E--------VS-AVVLLYMATQISSAMEYLEKKNFIHRNLAARNCLVGENH---LVKVADFGLSRLMTGD--T--YTAHAG-AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGID-L-SQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESS
17 PsiBlast_PDB 81.86100%-119 - C1 -3OCS A:[4-266] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WEIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREM-R---------------H------R--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEN-
121 HHSearch 81.6899%-122 - C1 -4OT5 A:[20-282] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREA-R---------------H------A--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
4 PsiBlast_PDB 81.6598%-121 - C1 -4OTR A:[20-282] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREA-R---------------H------A--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
2 PsiBlast_PDB 81.6098%-121 - C1 -4OT6 A:[18-282] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SWEIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREA-R---------------H------A--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
1 PsiBlast_PDB 81.3898%-122 - C1 -4OT5 A:[20-282] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREA-R---------------H------A--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
23 PsiBlast_CBE 81.2998%-122 - C1 -4RFY A:[20-282] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EIDPKDLTFLK-ELGTGQFGVVKYGKWR---G------Q--------Y-----DVAIKMIKEGS--MS---E--DEFIEEAKVMMNL-S-HEKLVQLYGVCTKQ-RPIFIITEYMANGCLLNYLREA-R---------------H------A--------FQ-TQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQG---VVKVSDFGLSRYVLDD--E--YTSSVG-SKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFT-N-SETAEHIAQGLRLYRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEE-
116 HHSearch 79.7039% -98 - C1 -1QCF HCK_HUMAN A:[9-444] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IIVVALYDYEAIHHEDLSFQKGDQMVVLE-ES--GEWWKARSL-A-TRKEGYIPSNYVARV-DSLETEEWFFKGISRKDAE-RQLLAPGN-MLGSFMIRDSETTKGSYSLSV--RDYDP-RQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSS---KPQKP--------------W---E--KDAWEIPRESLKLEK-KLGAGQFGEVWMATYN---K------H--------T-----KVAVKTMKPGS--MS---V--EAFLAEANVMKTL-Q-HDKLVKLHAVVT-K-EPIYIITEFMAKGSLLDFLKSDEG---------------S------K--------QP-LPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASL---VCKIADFGLARVIEDN--E--YTAREG-AKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMS-N-PEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATE
56 PsiBlast_CBE 79.4042% -93 - C1 -1OPK ABL1_MOUSE A:[47-466] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VALYDFVASGDNTLSITKGEKLRVLGYNH-NGEWCEAQ-T-K-NGQ-GWVPSNYITPV-NSLEKHSWYHGPVSRNAAE-YLLS-S-G-INGSFLVRESESSPGQRSISL--RY------EGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNK--PTIY--------------GVSPN--YDKWEMERTDITMKH-KLGGGQYGEVYEGVWK---KY-----S--------L-----TVAVKTLKEDT--ME---V--EEFLKEAAVMKEI-K-HPNLVQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNR---------------Q------E--------VS-AVVLLYMATQISSAMEYLEKKNFIHRNLAARNCLVGENH---LVKVADFGLSRLMTGD--T--YTAHAG-AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGID-L-SQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESS
97 PsiBlast_CBE 79.0039% -97 - C1 -4LUE HCK_HUMAN B:[11-441] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VVALYDYEAIHHEDLSFQKGDQMVVLE-ES-G-EWWKAR-SLA-TRKEGYIPSNYVARV-DSLETEEWFFKGISRKDAERQLLA-PGN-MLGSFMIRDSETTKGSYSLSVRDYDPRQGD---TVKHYKIRT----GFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQKPWEK--------------D--------AWEIPRESLKLEK-KLGAGQFGEVWMATYN---K------H--------T-----KVAVKTMKP---------------LAEANVMKTL-Q-HDKLVKLHAVVTKE--PIYIITEFMAKGSLLDFLKSD-E---------------G------S--------KQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASL---VCKIADFGLARVI------------------PIKWTAPEAINF---TIKSDVWSFGILLMEIVTYGRIPYPGMS-N-PEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATE
55 PsiBlast_CBE 78.9742% -93 - C1 -1OPL ABL1_HUMAN A:[86-505] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VALYDFVASGDNTLSITKGEKLRVLGYNH-NGEWCEAQ-T-K-NGQ-GWVPSNYITPV-NSLEKHSWYHGPVSRNAAE-YLLS-S-G-INGSFLVRESESSPGQRSISL--RY------EGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNK--PTVY--------------GVSPN--YDKWEMERTDITMKH-KLGGGQYGEVYEGVWK---KY-----S--------L-----TVAVKTLKEDT--ME---V--EEFLKEAAVMKEI-K-HPNLVQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNR---------------Q------E--------VN-AVVLLYMATQISSAMEYLEKKNFIHRNLAARNCLVGENH---LVKVADFGLSRLMTGD--T--YTAHAG-AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGID-L-SQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESS
57 PsiBlast_CBE 78.5642% -93 - C1 -2FO0 ABL1_HUMAN A:[44-463] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VALYDFVASGDNTLSITKGEKLRVLGYNH-NGEWCEAQ-T-K-NGQ-GWVPSNYITPV-NSLEKHSWYHGPVSRNAAE-YLLS-S-G-INGSFLVRESESSPGQRSISL--RY------EGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNK--PTVY--------------GVSPN--YDKWEMERTDITMKH-KLGGGQYGEVYEGVWK---KY-----S--------L-----TVAVKTLKEDT--ME---V--EEFLKEAAVMKEI-K-HPNLVQLLGVCTRE-PPFYIITEFMTYGNLLDYLRECNR---------------Q------E--------VN-AVVLLYMATQISSAMEYLEKKNFIHRNLAARNCLVGENH---LVKVADFGLSRLMTGD--T--YTAHAG-AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGID-L-SQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESS
102 PsiBlast_CBE 78.3739% -94 - C1 -3VS6 HCK_HUMAN B:[11-441] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VVALYDYEAIHHEDLSFQKGDQMVVLE-ES-G-EWWKAR-SLA-TRKEGYIPSNYVARV-DSLETEEWFFKGISRKDAERQLLA-PGN-MLGSFMIRDSETTKGSYSLSVRDYDPRQGD---TVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQKPWEK--------------D--------AWEIPRESLKLEK-KLGAGQFGEVWMATYN---K------H--------T-----KVAVKTMKPGS--MS---V--EAFLAEANVMKTL-Q-HDKLVKLHAVVTKE--PIYIITEFMAKGSLLDFLKSD-E---------------G------S--------KQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASL---VCKIADFGLARVI-----------------FPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMS-N-PEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATE
98 PsiBlast_CBE 77.8339% -96 - C1 -4LUE HCK_HUMAN A:[11-441] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VVALYDYEAIHHEDLSFQKGDQMVVLE-ES-G-EWWKAR-SLA-TRKEGYIPSNYVARV-DSLETEEWFFKGISRKDAERQLLA-PGN-MLGSFMIRDSETTKGSYSLSVRDYDPRQGD---TVKHYKIRT----GFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQKPWEK--------------D--------AWEIPRESLKLEK-KLGAGQFGEVWMATYN---K------H--------T-----KVAVKTMKPGS-------------LAEANVMKTL-Q-HDKLVKLHAVVTKE--PIYIITEFMAKGSLLDFLKSD-E---------------G------S--------KQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASL---VCKIADFGLARVI------------------PIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMS-N-PEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATE
100 PsiBlast_CBE 77.5139%-100 - C1 -4LUD HCK_HUMAN A:[11-441] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VVALYDYEAIHHEDLSFQKGDQMVVLE-ES-G-EWWKAR-SLA-TRKEGYIPSNYVAR----LETEEWFFKGISRKDAERQLLA-PGN-MLGSFMIRDSETTKGSYSLSVRDYDPRQGD---TVKHYKIRTLD--GFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQKPWEK--------------D--------AWEIPRESLKLEK-KLGAGQFGEVWMATYN---K------H--------T-----KVAVKTMKP-----S---V--EAFLAEANVMKTL-Q-HDKLVKLHAVVTKE--PIYIITEFM<