@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0913: (2015-12-19 )
MVHQSEMENYNIGQASIEEVSDPAYKGAKIVVVGVGGGGSNMIKHLVEYGVHQDVTPIATNTDGQHLKNNPAPVKILLGKESTGGLGAGGVPDIGKKAAEESADEIREAIKDAKLVIVSTGLGGGTGTGATPTIVKIAKEVGALTIAIVTKPFKYEGNQKRKRAEEGLKELEQSSDSILVIPNDKILLTMKKNASTTECYREVDDVLVRAVSGISTIITKPGNINVDFADLKSALGFKGFALMGIGEATGEDSAKLAVQNAIQSPLLDDASIEGAKSIIVFFEHHPDYPMMAYSQACDFIQDQAHQDVDVKFGQHTSENIPIDHVRVTIIATGSERNSNGAGLESIATPSQPVVKPTRKVGNGEYLRIPTEEELSIPTTIRIQQD
Atome Classification :
(47 SA)
.........10........20....---....30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.--......340.......350.......360.......370.......380...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MV
H
Q
S
E
MENYNIG
Q
A
S
I
E
EVSDPAY---KG
A
K
I
V
V
V
G
VGGG
G
S
N
M
I
K
H
L
V
E
YGVHQDVTPIATNTDGQHLKNNPA
P
V
K
I
L
L
GKESTGGLGAGGV
P
D
I
G
K
K
A
A
E
E
S
A
D
E
I
R
E
A
IKDA
K
L
V
I
V
S
TGLGGGTGTGA
T
P
T
I
V
K
I
A
K
EVG
A
L
T
I
A
I
V
TK
P
F
KYEG
N
Q
K
R
K
R
A
E
E
G
L
K
E
L
E
QSSD
S
I
L
V
IPN
D
K
I
L
L
T
MKKNA
S
T
T
E
C
Y
R
E
V
D
D
V
L
V
R
A
V
SG
I
S
T
I
ITKPGN
I
N
V
D
F
A
D
L
K
S
A
LGFK
G
F
A
L
M
G
IGEATGE
D
S
A
K
L
A
V
Q
N
A
I
QSPLLDDASIEGA
K
S
I
I
V
F
F
EHHPDY
P
M
M
A
Y
S
Q
A
C
D
F
I
Q
D
QAHQDV
D
V
KFGQHTSENIPI
D
H
V
R
V
T
I
I
A
TG--SERNSNGAGLESIATPSQPVVK
P
T
RKVGNG
E
Y
L
RIP
T
E
EELSI
P
T
T
I
R
I
QQD
43
PsiBlast_CBE
97.28
41%
-93
- C3 -
2VAP
1
FTSZ1_METJA
A:
[20-341]
------------
L
E
L
S
P
E
D
K
E
L
L
E
Y
L
Q
Q
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
W
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
-------------------------------------
70
HHSearch
97.23
41%
-91
- C3 -
2VAP
1
FTSZ1_METJA
A:
[33-348]
----------------------
L
Q
Q
---
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
-
E
G
A
K
T
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
L
F
E
I
V
P
-
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
W
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
-------------------------------------
65
HHSearch
97.23
43%
-101
* C3 *
2VXY
2
FTSZ_BACSU
A:
[11-316]
-----------------------------
L
A
S
I
K
V
I
G
V
G
G
G
G
N
N
A
V
N
R
M
I
E
N
E
V
-
Q
G
V
E
Y
I
A
V
N
T
D
A
Q
A
L
N
L
S
K
A
E
V
K
M
Q
I
G
A
K
L
T
R
G
L
G
A
G
A
N
P
E
V
G
K
K
A
A
E
E
S
K
E
Q
I
E
E
A
L
K
G
A
D
M
V
F
V
T
A
G
M
G
G
G
T
G
T
G
A
A
P
V
I
A
Q
I
A
K
D
L
G
A
L
T
V
G
V
V
T
R
P
F
T
F
E
G
R
K
R
Q
L
Q
A
A
G
G
I
S
A
M
K
E
A
V
D
T
L
I
V
I
P
N
D
R
I
L
E
I
V
D
K
N
T
P
M
L
E
A
F
R
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
T
P
G
L
I
N
L
D
F
A
D
V
K
T
I
M
S
N
K
G
S
A
L
M
G
I
G
I
A
T
G
E
N
R
A
A
E
A
A
K
K
A
I
S
S
P
L
L
E
-
A
A
I
D
G
A
Q
G
V
L
M
N
I
T
G
G
T
N
L
S
L
Y
E
V
Q
E
A
A
D
I
V
A
S
A
S
D
Q
D
V
N
M
I
F
G
S
V
I
N
E
N
L
K
-
D
E
I
V
V
T
V
I
A
T
G
--
F
I
--------------------------------------------------
69
HHSearch
96.87
43%
-92
- C3 -
1OFU
1
FTSZ_PSEAE
A:
[11-317]
-----------------------------
T
A
V
I
K
V
I
G
V
G
G
G
G
G
N
A
V
N
H
M
A
K
N
N
V
-
E
G
V
E
F
I
C
A
N
T
D
A
Q
A
L
K
N
I
A
A
R
T
V
L
Q
L
G
P
G
V
T
K
G
L
G
A
G
A
N
P
E
V
G
R
Q
A
A
L
E
D
R
E
R
I
S
E
V
L
E
G
A
D
M
V
F
I
T
T
G
M
G
G
G
T
G
T
G
A
A
P
I
I
A
E
V
A
K
E
M
G
I
L
T
V
A
V
V
T
R
P
F
P
F
E
G
R
K
R
M
Q
I
A
D
E
G
I
R
A
L
A
E
S
V
D
S
L
I
T
I
P
N
E
K
L
L
T
I
L
G
K
D
A
S
L
L
A
A
F
A
K
A
D
D
V
L
A
G
A
V
R
G
I
S
D
I
I
K
R
P
G
M
I
N
V
D
F
A
D
V
K
T
V
M
S
E
M
G
M
A
M
M
G
T
G
C
A
S
G
P
N
R
A
R
E
A
T
E
A
A
I
R
N
P
L
L
E
D
V
N
L
Q
G
A
R
G
I
L
V
N
I
T
A
G
P
D
L
S
L
G
E
Y
S
D
V
G
N
I
I
E
Q
F
A
S
E
H
A
T
V
K
V
G
T
V
I
D
A
D
M
R
-
D
E
L
H
V
T
V
V
A
T
G
--
L
G
--------------------------------------------------
49
PsiBlast_CBE
96.58
41%
-87
- C3 -
1W59
1
FTSZ1_METJA
A:
[12-341]
----
S
K
L
E
E
F
--
L
E
L
S
P
E
D
K
E
L
L
E
Y
L
Q
Q
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
W
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
-------------------------------------
66
HHSearch
96.31
40%
-87
- C3 -
2VAW
1
FTSZ_PSEAE
A:
[6-316]
---------------------
D
N
I
A
---
Q
T
A
V
I
K
V
I
G
V
G
G
G
G
G
N
A
V
N
H
M
A
K
N
N
V
-
E
G
V
E
F
I
C
A
N
T
D
A
Q
A
L
K
N
I
A
A
R
T
V
L
Q
L
G
P
G
V
T
K
G
L
G
A
G
A
N
P
E
V
G
R
Q
A
A
L
E
D
R
E
R
I
S
E
V
L
E
G
A
D
M
V
F
I
T
T
G
M
G
G
G
T
G
T
G
A
A
P
I
I
A
E
V
A
K
E
M
G
I
L
T
V
A
V
V
T
R
P
F
P
F
E
G
R
K
R
M
Q
I
A
D
E
G
I
R
A
L
A
E
S
V
D
S
L
I
T
I
P
N
E
K
L
L
T
I
L
G
K
D
A
S
L
L
A
A
F
A
K
A
D
D
V
L
A
G
A
V
R
G
I
S
D
I
I
K
R
P
G
M
I
N
V
D
F
A
D
V
K
T
V
M
S
E
M
G
M
A
M
M
G
T
G
C
A
S
G
P
N
R
A
R
E
A
T
E
A
A
I
R
N
P
L
L
E
D
V
N
L
Q
G
A
R
G
I
L
V
N
I
T
A
G
P
D
L
S
L
G
E
Y
S
D
V
G
N
I
I
E
Q
F
A
S
E
H
A
T
V
K
V
G
T
V
I
D
A
D
M
R
-
D
E
L
H
V
T
V
V
A
T
G
--
L
---------------------------------------------------
45
PsiBlast_CBE
95.87
41%
-91
- C3 -
1W5B
1
FTSZ1_METJA
A:
[22-341]
--------------
L
S
P
E
D
K
E
L
L
E
Y
L
Q
Q
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
W
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
K
------------------------------------
67
HHSearch
95.80
43%
-97
- C3 -
1RQ2
1
FTSZ_MYCTU
A:
[11-315]
-----------------------------
L
A
V
I
K
V
V
G
I
G
G
G
G
V
N
A
V
N
R
M
I
E
Q
G
L
-
K
G
V
E
F
I
A
I
N
T
D
A
Q
A
L
L
M
S
D
A
D
V
K
L
D
V
G
R
D
S
T
-----
G
A
D
P
E
V
G
R
K
A
A
E
D
A
K
D
E
I
E
E
L
L
R
G
A
D
M
V
F
V
T
A
G
E
G
G
G
T
G
T
G
G
A
P
V
V
A
S
I
A
R
K
L
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
K
R
R
S
N
Q
A
E
N
G
I
A
A
L
R
E
S
C
D
T
L
I
V
I
P
N
D
R
L
L
Q
M
G
D
A
A
V
S
L
M
D
A
F
R
S
A
D
E
V
L
L
N
G
V
Q
G
I
T
D
L
I
T
T
P
G
L
I
N
V
D
F
A
D
V
K
G
I
M
S
G
A
G
T
A
L
M
G
I
G
S
A
R
G
E
G
R
S
L
K
A
A
E
I
A
I
N
S
P
L
L
E
-
A
S
M
E
G
A
Q
G
V
L
M
S
I
A
G
G
S
D
L
G
L
F
E
I
N
E
A
A
S
L
V
Q
D
A
A
H
P
D
A
N
I
I
F
G
T
V
I
D
D
S
L
G
-
D
E
V
R
V
T
V
I
A
A
G
--
F
---------------------------------------------------
59
PsiBlast_CBE
95.79
41%
-84
- C3 -
1W5E
1
FTSZ1_METJA
A:
[23-341]
---------------
S
P
E
D
K
E
L
L
E
Y
L
Q
Q
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
Y
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
-------------------------------------
56
PsiBlast_CBE
95.57
41%
-86
- C3 -
1W5E
1
FTSZ1_METJA
D:
[23-341]
---------------
S
P
E
D
K
E
L
L
E
Y
LQQ
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
Y
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
-------------------------------------
53
PsiBlast_CBE
95.53
41%
-85
- C3 -
1W5E
1
FTSZ1_METJA
G:
[23-341]
---------------
S
P
E
D
K
E
L
L
E
Y
LQQ
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
Y
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
-------------------------------------
54
PsiBlast_CBE
95.52
41%
-88
- C3 -
1W5E
1
FTSZ1_METJA
F:
[23-341]
---------------
S
P
E
D
K
E
L
L
E
Y
LQQ
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
Y
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
-------------------------------------
47
PsiBlast_CBE
95.52
41%
-85
- C3 -
1W5A
2
FTSZ1_METJA
A:
[22-341]
--------------
L
S
P
E
D
K
E
L
L
E
Y
L
Q
Q
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
W
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
K
------------------------------------
46
PsiBlast_CBE
95.46
41%
-88
- C3 -
1W5A
1
FTSZ1_METJA
B:
[22-341]
--------------
L
S
P
E
D
K
E
L
L
E
Y
LQQ
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
W
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
K
L
E
----------------------------------
55
PsiBlast_CBE
95.20
41%
-85
- C3 -
1W5E
1
FTSZ1_METJA
E:
[23-341]
---------------
S
P
E
D
K
E
L
L
E
Y
LQQ
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
Y
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
K
------------------------------------
57
PsiBlast_CBE
95.00
41%
-86
- C3 -
1W5E
1
FTSZ1_METJA
C:
[23-341]
---------------
S
P
E
D
K
E
L
L
E
Y
LQQ
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
Y
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
-------------------------------------
52
PsiBlast_CBE
95.00
41%
-85
- C3 -
1W5E
1
FTSZ1_METJA
H:
[23-341]
---------------
S
P
E
D
K
E
L
L
E
Y
LQQ
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
Y
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
K
------------------------------------
51
PsiBlast_CBE
94.92
41%
-85
- C3 -
1W5E
1
FTSZ1_METJA
I:
[23-341]
---------------
S
P
E
D
K
E
L
L
E
Y
LQQ
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
Y
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
-------------------------------------
48
PsiBlast_CBE
94.91
41%
-85
- C3 -
1W59
1
FTSZ1_METJA
B:
[22-341]
--------------
L
S
P
E
D
K
E
L
L
E
Y
L
Q
Q
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
W
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
K
L
E
L
T
G
I
P
K
I
---------------------------
44
PsiBlast_CBE
94.52
41%
-86
- C3 -
1W5B
1
FTSZ1_METJA
B:
[22-341]
--------------
L
S
P
E
D
K
E
L
L
E
Y
LQQ
T
K
A
K
I
T
V
V
G
C
G
G
A
G
N
N
T
I
T
R
L
K
M
E
G
I
E
G
A
K
T
-
V
A
I
N
T
D
A
Q
Q
L
I
R
T
K
A
D
K
K
I
L
I
G
K
K
L
T
R
G
L
G
A
G
G
N
P
K
I
G
E
E
A
A
K
E
S
A
E
E
I
K
A
A
I
Q
D
S
D
M
V
F
I
T
C
G
L
G
G
G
T
G
T
G
S
A
P
V
V
A
E
I
S
K
K
I
G
A
L
T
V
A
V
V
T
L
P
F
V
M
E
G
K
V
R
M
K
N
A
M
E
G
L
E
R
L
K
Q
H
T
D
T
L
V
V
I
P
N
E
K
-
L
F
E
I
V
P
N
M
P
L
K
L
A
F
K
V
A
D
E
V
L
I
N
A
V
K
G
L
V
E
L
I
T
K
D
G
L
I
N
V
D
F
A
D
V
K
A
V
M
N
N
G
G
L
A
M
I
G
I
G
E
S
D
S
E
K
R
A
K
E
A
V
S
M
A
L
N
S
P
L
L
D
-
V
D
I
D
G
A
T
G
A
L
I
H
V
M
G
P
E
D
L
T
L
E
E
A
R
E
V
V
A
T
V
S
S
R
L
D
P
N
A
T
I
I
W
G
A
T
I
D
E
N
L
E
-
N
T
V
R
V
L
L
V
I
T
G
--
V
Q
S
R
I
E
F
T
D
T
G
L
K
R
K
K
L
E
----------------------------------
22
PsiBlast_CBE
94.07
45%
-89
- C3 -
2RHL
1
FTSZ_BACSU
B:
[19-308]
-----------------------------------------------
R
M
I
E
N
E
V
-
Q
G
V
E
Y
I
A
V
N
T
D
A
Q
A
L
N
L
S
K
A
E
V
K
M
Q
I
G
A
K
L
T
R
G
L
G
A
G
A
N
P
E
V
G
K
K
A
A
E
E
S
K
E
Q
I
E
E
A
L
K
G
A
D
M
V
F
V
T
A
G
M
G
G
G
T
G
T
G
A
A
P
V
I
A
Q
I
A
K
D
L
G
A
L
T
V
G
V
V
T
R
P
F
T
F
E
G
R
K
R
Q
L
Q
A
A
G
G
I
S
A
M
K
E
A
V
D
T
L
I
V
I
P
N
D
R
I
L
E
I
V
D
K
N
T
P
M
L
E
A
F
R
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
T
P
G
L
I
N
L
D
F
A
D
V
K
T
I
M
S
N
K
G
S
A
L
M
G
I
G
I
A
T
G
E
N
R
A
A
E
A
A
K
K
A
I
S
S
P
L
L
-
E
A
A
I
D
G
A
Q
G
V
L
M
N
I
T
G
G
T
N
L
S
L
Y
E
V
Q
E
A
A
D
I
V
A
S
A
S
D
Q
D
V
N
M
I
F
G
S
V
I
N
E
N
L
K
-
D
E
I
V
V
T
V
I
A
T
G
--
F
L
E
N
L
Y
F
Q
G
H
H
H
----------------------------------------
5
PsiBlast_PDB
93.31
45%
-98
- C3 -
2RHL
1
FTSZ_BACSU
A:
[19-306]
-----------------------------------------------
R
M
I
E
N
E
V
-
Q
G
V
E
Y
I
A
V
N
T
D
A
Q
A
L
N
L
S
K
A
E
V
K
M
Q
I
G
A
K
L
T
R
G
L
G
A
G
A
N
P
E
V
G
K
K
A
A
E
E
S
K
E
Q
I
E
E
A
L
K
G
A
D
M
V
F
V
T
A
G
M
G
G
G
T
G
T
G
A
A
P
V
I
A
Q
I
A
K
D
L
G
A
L
T
V
G
V
V
T
R
P
F
T
F
E
G
R
K
R
Q
L
Q
A
A
G
G
I
S
A
M
K
E
A
V
D
T
L
I
V
I
P
N
D
R
I
L
E
I
V
D
K
N
T
P
M
L
E
A
F
R
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
T
P
G
L
I
N
L
D
F
A
D
V
K
T
I
M
S
N
K
G
S
A
L
M
G
I
G
I
A
T
G
E
N
R
A
A
E
A
A
K
K
A
I
S
S
P
L
L
-
E
A
A
I
D
G
A
Q
G
V
L
M
N
I
T
G
G
T
N
L
S
L
Y
E
V
Q
E
A
A
D
I
V
A
S
A
S
D
Q
D
V
N
M
I
F
G
S
V
I
N
E
N
L
K
-
D
E
I
V
V
T
V
I
A
T
G
--
F
L
--------------------------------------------------
21
PsiBlast_CBE
93.26
45%
-93
- C3 -
2RHO
1
FTSZ_BACSU
B:
[19-305]
-----------------------------------------------
R
M
I
E
N
E
V
-
Q
G
V
E
Y
I
A
V
N
T
D
A
Q
A
L
N
L
S
K
A
E
V
K
M
Q
I
G
A
K
L
T
R
G
L
G
A
G
A
N
P
E
V
G
K
K
A
A
E
E
S
K
E
Q
I
E
E
A
L
K
G
A
D
M
V
F
V
T
A
G
M
G
G
G
T
G
T
G
A
A
P
V
I
A
Q
I
A
K
D
L
G
A
L
T
V
G
V
V
T
R
P
F
T
F
E
G
R
K
R
Q
L
Q
A
A
G
G
I
S
A
M
K
E
A
V
D
T
L
I
V
I
P
N
D
R
I
L
E
I
V
D
K
N
T
P
M
L
E
A
F
R
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
T
P
G
L
I
N
L
D
F
A
D
V
K
T
I
M
S
N
--
S
A
L
M
G
I
G
I
A
T
G
E
N
R
A
A
E
A
A
K
K
A
I
S
S
P
L
L
-
E
A
A
I
D
G
A
Q
G
V
L
M
N
I
T
G
G
T
N
L
S
L
Y
E
V
Q
E
A
A
D
I
V
A
S
A
S
D
Q
D
V
N
M
I
F
G
S
V
I
N
E
N
L
K
-
D
E
I
V
V
T
V
I
A
T
G
--
F
---------------------------------------------------
13
PsiBlast_PDB
92.99
43%
-95
- C3 -
4KWE
1
FTSZ_MYCTU
A:
[25-314]
-------------------------------------------
N
A
V
N
R
M
I
E
Q
G
L
-
K
G
V
E
F
I
A
I
N
T
D
A
Q
A
L
L
M
S
D
A
D
V
K
L
D
V
G
R
D
S
T
R
G
L
G
A
G
A
D
P
E
V
G
R
K
A
A
E
D
A
K
D
E
I
E
E
L
L
R
G
A
D
M
V
F
V
T
A
G
E
G
G
G
T
G
T
G
G
A
P
V
V
A
S
I
A
R
K
L
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
K
R
R
S
N
Q
A
E
N
G
I
A
A
L
R
E
S
C
D
T
L
I
V
I
P
N
D
R
L
L
Q
M
G
D
A
A
V
S
L
M
D
A
F
R
S
A
D
E
V
L
L
N
G
V
Q
G
I
T
D
L
I
T
T
P
G
L
I
N
V
D
F
A
D
V
K
G
I
M
S
G
A
G
T
A
L
M
G
I
G
S
A
R
G
E
G
R
S
L
K
A
A
E
I
A
I
N
S
P
L
L
-
E
A
S
M
E
G
A
Q
G
V
L
M
S
I
A
G
G
S
D
L
G
L
F
E
I
N
E
A
A
S
L
V
Q
D
A
A
H
P
D
A
N
I
I
F
G
T
V
I
D
D
S
L
G
-
D
E
V
R
V
T
V
I
A
A
G
--
F
---------------------------------------------------
6
PsiBlast_PDB
92.87
45%
-95
- C3 -
2RHO
1
FTSZ_BACSU
A:
[19-306]
-----------------------------------------------
R
M
I
E
N
E
V
-
Q
G
V
E
Y
I
A
V
N
T
D
A
Q
A
L
N
L
S
K
A
E
V
K
M
Q
I
G
A
K
L
T
R
G
L
G
A
G
A
N
P
E
V
G
K
K
A
A
E
E
S
K
E
Q
I
E
E
A
L
K
G
A
D
M
V
F
V
T
A
G
M
G
G
G
T
G
T
G
A
A
P
V
I
A
Q
I
A
K
D
L
G
A
L
T
V
G
V
V
T
R
P
F
T
F
E
G
R
K
R
Q
L
Q
A
A
G
G
I
S
A
M
K
E
A
V
D
T
L
I
V
I
P
N
D
R
I
L
E
I
V
D
K
N
T
P
M
L
E
A
F
R
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
T
P
G
L
I
N
L
D
F
A
D
V
K
T
I
M
S
N
K
G
S
A
L
M
G
I
G
I
A
T
G
E
N
R
A
A
E
A
A
K
K
A
I
S
S
P
L
L
-
E
A
A
I
D
G
A
Q
G
V
L
M
N
I
T
G
G
T
N
L
S
L
Y
E
V
Q
E
A
A
D
I
V
A
S
A
S
D
Q
D
V
N
M
I
F
G
S
V
I
N
E
N
L
K
-
D
E
I
V
V
T
V
I
A
T
G
--
F
L
--------------------------------------------------
34
PsiBlast_CBE
92.64
42%
-87
- C3 -
2VAW
1
FTSZ_PSEAE
A:
[25-315]
-------------------------------------------
N
A
V
N
H
M
A
K
N
N
V
-
E
G
V
E
F
I
C
A
N
T
D
A
Q
A
L
K
N
I
A
A
R
T
V
L
Q
L
G
P
G
V
T
K
G
L
G
A
G
A
N
P
E
V
G
R
Q
A
A
L
E
D
R
E
R
I
S
E
V
L
E
G
A
D
M
V
F
I
T
T
G
M
G
G
G
T
G
T
G
A
A
P
I
I
A
E
V
A
K
E
M
G
I
L
T
V
A
V
V
T
R
P
F
P
F
E
G
R
K
R
M
Q
I
A
D
E
G
I
R
A
L
A
E
S
V
D
S
L
I
T
I
P
N
E
K
L
L
T
I
L
G
K
D
A
S
L
L
A
A
F
A
K
A
D
D
V
L
A
G
A
V
R
G
I
S
D
I
I
K
R
P
G
M
I
N
V
D
F
A
D
V
K
T
V
M
S
E
M
G
M
A
M
M
G
T
G
C
A
S
G
P
N
R
A
R
E
A
T
E
A
A
I
R
N
P
L
L
E
D
V
N
L
Q
G
A
R
G
I
L
V
N
I
T
A
G
P
D
L
S
L
G
E
Y
S
D
V
G
N
I
I
E
Q
F
A
S
E
H
A
T
V
K
V
G
T
V
I
D
A
D
M
R
-
D
E
L
H
V
T
V
V
A
T
G
--
L
---------------------------------------------------
32
PsiBlast_CBE
92.47
42%
-88
- C3 -
1OFU
1
FTSZ_PSEAE
B:
[25-315]
-------------------------------------------
N
A
V
N
H
M
A
K
N
N
V
-
E
G
V
E
F
I
C
A
N
T
D
A
Q
A
L
K
N
I
A
A
R
T
V
L
Q
L
G
P
G
V
T
K
G
L
G
A
G
A
N
P
E
V
G
R
Q
A
A
L
E
D
R
E
R
I
S
E
V
L
E
G
A
D
M
V
F
I
T
T
G
M
G
G
G
T
G
T
G
A
A
P
I
I
A
E
V
A
K
E
M
G
I
L
T
V
A
V
V
T
R
P
F
P
F
E
G
R
K
R
M
Q
I
A
D
E
G
I
R
A
L
A
E
S
V
D
S
L
I
T
I
P
N
E
K
L
L
T
I
L
G
K
D
A
S
L
L
A
A
F
A
K
A
D
D
V
L
A
G
A
V
R
G
I
S
D
I
I
K
R
P
G
M
I
N
V
D
F
A
D
V
K
T
V
M
S
E
M
G
M
A
M
M
G
T
G
C
A
S
G
P
N
R
A
R
E
A
T
E
A
A
I
R
N
P
L
L
E
D
V
N
L
Q
G
A
R
G
I
L
V
N
I
T
A
G
P
D
L
S
L
G
E
Y
S
D
V
G
N
I
I
E
Q
F
A
S
E
H
A
T
V
K
V
G
T
V
I
D
A
D
M
R
-
D
E
L
H
V
T
V
V
A
T
G
--
L
G
--------------------------------------------------
9
PsiBlast_PDB
92.36
43%
-92
- C3 -
2Q1Y
1
FTSZ_MYCTU
A:
[22-311]
-------------------------------------------
N
A
V
N
R
M
I
E
Q
G
L
-
K
G
V
E
F
I
A
I
N
T
D
A
Q
A
L
L
M
S
D
A
D
V
K
L
D
V
G
R
D
S
T
R
G
L
G
A
G
A
D
P
E
V
G
R
K
A
A
E
D
A
K
D
E
I
E
E
L
L
R
G
A
D
M
V
F
V
T
A
G
E
G
G
G
T
G
T
G
G
A
P
V
V
A
S
I
A
R
K
L
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
K
R
R
S
N
Q
A
E
N
G
I
A
A
L
R
E
S
C
D
T
L
I
V
I
P
N
D
R
L
L
Q
M
G
D
A
A
V
S
L
M
D
A
F
R
S
A
D
E
V
L
L
N
G
V
Q
G
I
T
D
L
I
T
T
P
G
L
I
N
V
D
F
A
D
V
K
G
I
M
S
G
A
G
T
A
L
M
G
I
G
S
A
R
G
E
G
R
S
L
K
A
A
E
I
A
I
N
S
P
L
L
-
E
A
S
M
E
G
A
Q
G
V
L
M
S
I
A
G
G
S
D
L
G
L
F
E
I
N
E
A
A
S
L
V
Q
D
A
A
H
P
D
A
N
I
I
F
G
T
V
I
D
D
S
L
G
-
D
E
V
R
V
T
V
I
A
A
G
--
F
---------------------------------------------------
37
PsiBlast_CBE
92.09
42%
-92
- C3 -
3WGL
1
FTSZ_STAAM
B:
[31-314]
-----------------------------------------------
R
M
I
D
H
G
M
N
-
N
V
E
F
I
A
I
N
T
D
G
Q
A
L
N
L
S
K
A
E
S
K
I
Q
I
G
E
K
L
T
R
G
L
G
A
G
A
N
P
E
I
G
K
K
A
A
E
E
S
R
E
Q
I
E
D
A
I
Q
G
A
D
M
V
F
V
T
S
G
M
G
G
G
T
G
T
G
A
A
P
V
V
A
K
I
A
K
E
M
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
R
K
R
Q
T
Q
A
A
A
G
V
E
A
M
K
A
A
V
D
T
L
I
V
I
P
N
D
R
L
L
D
I
V
D
K
S
T
P
M
M
E
A
F
K
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
V
G
A
N
L
--
D
F
A
D
V
K
T
I
M
S
N
Q
G
S
A
L
M
G
I
G
V
S
S
G
E
N
R
A
V
E
A
A
K
K
A
I
S
S
P
L
L
-
E
T
S
I
V
G
A
Q
G
V
L
M
N
I
T
G
G
E
S
L
S
L
F
E
A
Q
E
A
A
D
I
V
Q
D
A
A
D
E
D
V
N
M
I
F
G
T
V
I
N
P
E
L
Q
-
D
E
I
V
V
T
V
I
A
T
G
--
F
D
--------------------------------------------------
10
PsiBlast_PDB
91.90
43%
-92
- C3 -
1RLU
2
FTSZ_MYCTU
A:
[25-314]
-------------------------------------------
N
A
V
N
R
M
I
E
Q
G
L
-
K
G
V
E
F
I
A
I
N
T
D
A
Q
A
L
L
M
S
D
A
D
V
K
L
D
V
G
R
D
S
T
R
G
L
G
A
G
A
D
P
E
V
G
R
K
A
A
E
D
A
K
D
E
I
E
E
L
L
R
G
A
D
M
V
F
V
T
A
G
E
G
G
G
T
G
T
G
G
A
P
V
V
A
S
I
A
R
K
L
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
K
R
R
S
N
Q
A
E
N
G
I
A
A
L
R
E
S
C
D
T
L
I
V
I
P
N
D
R
L
L
Q
M
G
D
A
A
V
S
L
M
D
A
F
R
S
A
D
E
V
L
L
N
G
V
Q
G
I
T
D
L
I
T
T
P
G
L
I
N
V
D
F
A
D
V
K
G
I
M
S
G
A
G
T
A
L
M
G
I
G
S
A
R
G
E
G
R
S
L
K
A
A
E
I
A
I
N
S
P
L
L
-
E
A
S
M
E
G
A
Q
G
V
L
M
S
I
A
G
G
S
D
L
G
L
F
E
I
N
E
A
A
S
L
V
Q
D
A
A
H
P
D
A
N
I
I
F
G
T
V
I
D
D
S
L
G
-
D
E
V
R
V
T
V
I
A
A
G
--
F
---------------------------------------------------
33
PsiBlast_CBE
91.85
42%
-88
- C3 -
1OFU
1
FTSZ_PSEAE
A:
[25-315]
-------------------------------------------
N
A
V
N
H
M
A
K
N
N
V
-
E
G
V
E
F
I
C
A
N
T
D
A
Q
A
L
K
N
I
A
A
R
T
V
L
Q
L
G
P
G
V
T
K
G
L
G
A
G
A
N
P
E
V
G
R
Q
A
A
L
E
D
R
E
R
I
S
E
V
L
E
G
A
D
M
V
F
I
T
T
G
M
G
G
G
T
G
T
G
A
A
P
I
I
A
E
V
A
K
E
M
G
I
L
T
V
A
V
V
T
R
P
F
P
F
E
G
R
K
R
M
Q
I
A
D
E
G
I
R
A
L
A
E
S
V
D
S
L
I
T
I
P
N
E
K
L
L
T
I
L
G
K
D
A
S
L
L
A
A
F
A
K
A
D
D
V
L
A
G
A
V
R
G
I
S
D
I
I
K
R
P
G
M
I
N
V
D
F
A
D
V
K
T
V
M
S
E
M
G
M
A
M
M
G
T
G
C
A
S
G
P
N
R
A
R
E
A
T
E
A
A
I
R
N
P
L
L
E
D
V
N
L
Q
G
A
R
G
I
L
V
N
I
T
A
G
P
D
L
S
L
G
E
Y
S
D
V
G
N
I
I
E
Q
F
A
S
E
H
A
T
V
K
V
G
T
V
I
D
A
D
M
R
-
D
E
L
H
V
T
V
V
A
T
G
--
L
G
--------------------------------------------------
11
PsiBlast_PDB
91.71
43%
-94
- C3 -
1RQ2
1
FTSZ_MYCTU
A:
[25-314]
-------------------------------------------
N
A
V
N
R
M
I
E
Q
G
L
-
K
G
V
E
F
I
A
I
N
T
D
A
Q
A
L
L
M
S
D
A
D
V
K
L
D
V
G
R
D
S
T
-----
G
A
D
P
E
V
G
R
K
A
A
E
D
A
K
D
E
I
E
E
L
L
R
G
A
D
M
V
F
V
T
A
G
E
G
G
G
T
G
T
G
G
A
P
V
V
A
S
I
A
R
K
L
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
K
R
R
S
N
Q
A
E
N
G
I
A
A
L
R
E
S
C
D
T
L
I
V
I
P
N
D
R
L
L
Q
M
G
D
A
A
V
S
L
M
D
A
F
R
S
A
D
E
V
L
L
N
G
V
Q
G
I
T
D
L
I
T
T
P
G
L
I
N
V
D
F
A
D
V
K
G
I
M
S
G
A
G
T
A
L
M
G
I
G
S
A
R
G
E
G
R
S
L
K
A
A
E
I
A
I
N
S
P
L
L
-
E
A
S
M
E
G
A
Q
G
V
L
M
S
I
A
G
G
S
D
L
G
L
F
E
I
N
E
A
A
S
L
V
Q
D
A
A
H
P
D
A
N
I
I
F
G
T
V
I
D
D
S
L
G
-
D
E
V
R
V
T
V
I
A
A
G
--
F
---------------------------------------------------
38
PsiBlast_CBE
91.36
42%
-92
- C3 -
3WGL
1
FTSZ_STAAM
A:
[31-314]
-----------------------------------------------
R
M
I
D
H
G
M
N
-
N
V
E
F
I
A
I
N
T
D
G
Q
A
L
N
L
S
K
A
E
S
K
I
Q
I
G
E
K
L
T
R
G
L
G
A
G
A
N
P
E
I
G
K
K
A
A
E
E
S
R
E
Q
I
E
D
A
I
Q
G
A
D
M
V
F
V
T
S
G
M
G
G
G
T
G
T
G
A
A
P
V
V
A
K
I
A
K
E
M
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
R
K
R
Q
T
Q
A
A
A
G
V
E
A
M
K
A
A
V
D
T
L
I
V
I
P
N
D
R
L
L
D
I
V
D
K
S
T
P
M
M
E
A
F
K
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
V
G
A
N
L
--
D
F
A
D
V
K
T
I
M
S
N
Q
G
S
A
L
M
G
I
G
V
S
S
G
E
N
R
A
V
E
A
A
K
K
A
I
S
S
P
L
L
-
E
T
S
I
V
G
A
Q
G
V
L
M
N
I
T
G
G
E
S
L
S
L
F
E
A
Q
E
A
A
D
I
V
Q
D
A
A
D
E
D
V
N
M
I
F
G
T
V
I
N
P
E
L
Q
-
D
E
I
V
V
T
V
I
A
T
G
--
F
---------------------------------------------------
2
PsiBlast_PDB
91.23
41%
-98
- C3 -
2VXY
2
FTSZ_BACSU
A:
[29-316]
-----------------------------------------------
R
M
I
E
N
E
V
-
Q
G
V
E
Y
I
A
V
N
T
D
A
Q
A
L
N
L
S
K
A
E
V
K
M
Q
I
G
A
K
L
T
R
G
L
G
A
G
A
N
P
E
V
G
K
K
A
A
E
E
S
K
E
Q
I
E
E
A
L
K
G
A
D
M
V
F
V
T
A
G
M
G
G
G
T
G
T
G
A
A
P
V
I
A
Q
I
A
K
D
L
G
A
L
T
V
G
V
V
T
R
P
F
T
F
E
G
R
K
R
Q
L
Q
A
A
G
G
I
S
A
M
K
E
A
V
D
T
L
I
V
I
P
N
D
R
I
L
E
I
V
D
K
N
T
P
M
L
E
A
F
R
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
T
P
G
L
I
N
L
D
F
A
D
V
K
T
I
M
S
N
K
G
S
A
L
M
G
I
G
I
A
T
G
E
N
R
A
A
E
A
A
K
K
A
I
S
S
P
L
L
-
E
A
A
I
D
G
A
Q
G
V
L
M
N
I
T
G
G
T
N
L
S
L
Y
E
V
Q
E
A
A
D
I
V
A
S
A
S
D
Q
D
V
N
M
I
F
G
S
V
I
N
E
N
L
K
-
D
E
I
V
V
T
V
I
A
T
G
FI----------------------------------------------------
35
PsiBlast_CBE
90.77
42%
-90
- C3 -
3WGM
1
FTSZ_STAAM
B:
[31-314]
-----------------------------------------------
R
M
I
D
H
G
M
N
-
N
V
E
F
I
A
I
N
T
D
G
Q
A
L
N
L
S
K
A
E
S
K
I
Q
I
G
E
K
L
T
R
G
L
G
A
G
A
N
P
E
I
G
K
K
A
A
E
E
S
R
E
Q
I
E
D
A
I
Q
G
A
D
M
V
F
V
T
S
G
M
G
G
G
T
G
T
G
A
A
P
V
V
A
K
I
A
K
E
M
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
R
K
R
Q
T
Q
A
A
A
G
V
E
A
M
K
A
A
V
D
T
L
I
V
I
P
N
D
R
L
L
D
I
V
D
K
S
T
P
M
M
E
A
F
K
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
V
G
A
N
L
--
D
F
A
D
V
K
T
I
M
S
N
Q
G
S
A
L
M
G
I
G
V
S
S
G
E
N
R
A
V
E
A
A
K
K
A
I
S
S
P
L
L
-
E
T
S
I
V
G
A
Q
G
V
L
M
N
I
T
G
G
E
S
L
S
L
F
E
A
Q
E
A
A
D
I
V
Q
D
A
A
D
E
D
V
N
M
I
F
G
T
V
I
N
P
E
L
Q
-
D
E
I
V
V
T
V
I
A
T
G
------------------------------------------------------
42
PsiBlast_CBE
90.70
42%
-96
- C3 -
3WGK
1
FTSZ_STAAM
A:
[31-314]
-----------------------------------------------
R
M
I
D
H
G
M
N
-
N
V
E
F
I
A
I
N
T
D
G
Q
A
L
N
L
S
K
A
E
S
K
I
Q
I
G
E
K
L
T
R
G
L
G
A
G
A
N
P
E
I
G
K
K
A
A
E
E
S
R
E
Q
I
E
D
A
I
Q
G
A
D
M
V
F
V
T
S
G
M
G
G
G
T
G
T
G
A
A
P
V
V
A
K
I
A
K
E
M
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
R
K
R
Q
T
Q
A
A
A
G
V
E
A
M
K
A
A
V
D
T
L
I
V
I
P
N
D
R
L
L
D
I
V
D
K
S
T
P
M
M
E
A
F
K
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
V
G
A
G
L
--
D
F
A
D
V
K
T
I
M
S
N
Q
G
S
A
L
M
G
I
G
V
S
S
G
E
N
R
A
V
E
A
A
K
K
A
I
S
S
P
L
L
-
E
T
S
I
V
G
A
Q
G
V
L
M
N
I
T
G
G
E
S
L
S
L
F
E
A
Q
E
A
A
D
I
V
Q
D
A
A
D
E
D
V
N
M
I
F
G
T
V
I
N
P
E
L
Q
-
D
E
I
V
V
T
V
I
A
T
G
--
F
D
--------------------------------------------------
18
PsiBlast_PDB
90.48
42%
-85
- C3 -
4M8I
2
FTSZ_STAEQ
A:
[35-327]
-----------------------------------------------
R
M
I
D
H
G
M
N
-
N
V
E
F
I
A
I
N
T
D
G
Q
A
L
N
L
S
K
A
E
S
K
I
Q
I
G
E
K
L
T
R
G
L
G
A
G
A
N
P
E
I
G
K
K
A
A
E
E
S
R
E
Q
I
E
D
A
I
Q
G
A
D
M
V
F
V
T
A
G
M
G
G
G
T
G
T
G
A
A
P
V
V
A
K
I
A
K
E
M
G
A
L
T
V
G
V
V
T
R
P
F
G
F
E
G
R
K
R
Q
T
Q
A
A
A
G
V
E
S
M
K
A
A
V
D
T
L
I
V
I
P
N
D
R
L
L
D
I
V
D
K
S
T
P
M
M
E
A
F
K
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
V
S
G
E
V
N
L
D
F
A
D
V
K
T
I
M
S
N
Q
G
S
A
L
M
G
I
G
V
S
S
G
E
N
R
A
V
E
A
A
K
K
A
I
S
S
P
L
L
-
E
T
S
I
V
G
A
Q
G
V
L
M
N
I
T
G
G
E
S
L
S
L
F
E
A
Q
E
A
A
D
I
V
Q
D
A
A
D
E
D
V
N
M
I
F
G
T
V
I
N
P
E
L
Q
-
D
E
I
V
V
T
V
I
A
T
G
--
F
E
D
K
P
S
S
---------------------------------------------
36
PsiBlast_CBE
90.22
42%
-92
- C3 -
3WGM
1
FTSZ_STAAM
A:
[31-314]
-----------------------------------------------
R
M
I
D
H
G
M
N
-
N
V
E
F
I
A
I
N
T
D
G
Q
A
L
N
L
S
K
A
E
S
K
I
Q
I
G
E
K
L
T
R
G
L
G
A
G
A
N
P
E
I
G
K
K
A
A
E
E
S
R
E
Q
I
E
D
A
I
Q
G
A
D
M
V
F
V
T
S
G
M
G
G
G
T
G
T
G
A
A
P
V
V
A
K
I
A
K
E
M
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
R
K
R
Q
T
Q
A
A
A
G
V
E
A
M
K
A
A
V
D
T
L
I
V
I
P
N
D
R
L
L
D
I
V
D
K
S
T
P
M
M
E
A
F
K
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
V
G
A
N
L
--
D
F
A
D
V
K
T
I
M
S
N
Q
G
S
A
L
M
G
I
G
V
S
S
G
E
N
R
A
V
E
A
A
K
K
A
I
S
S
P
L
L
-
E
T
S
I
V
G
A
Q
G
V
L
M
N
I
T
G
G
E
S
L
S
L
F
E
A
Q
E
A
A
D
I
V
Q
D
A
A
D
E
D
V
N
M
I
F
G
T
V
I
N
P
E
L
Q
-
D
E
I
V
V
T
V
I
A
T
G
------------------------------------------------------
31
PsiBlast_CBE
90.19
43%
-85
- C3 -
3VO8
2
FTSZ_STAAM
B:
[31-316]
-----------------------------------------------
R
M
I
D
H
G
M
N
-
N
V
E
F
I
A
I
N
T
D
G
Q
A
L
N
L
S
K
A
E
S
K
I
Q
I
G
E
K
L
T
R
G
L
G
A
G
A
N
P
E
I
G
K
K
A
A
E
E
S
R
E
Q
I
E
D
A
I
Q
G
A
D
M
V
F
V
T
S
G
M
G
G
G
T
G
T
G
A
A
P
V
V
A
K
I
A
K
E
M
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
R
K
R
Q
T
Q
A
A
A
G
V
E
A
M
K
A
A
V
D
T
L
I
V
I
P
N
D
R
L
L
D
I
V
D
K
S
T
P
M
M
E
A
F
K
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
V
S
G
E
V
N
L
D
F
A
D
V
K
T
I
M
S
N
Q
G
S
A
L
M
G
I
G
V
S
S
G
E
N
R
A
V
E
A
A
K
K
A
I
S
S
P
L
L
-
E
T
S
I
V
G
A
Q
G
V
L
M
N
I
T
G
G
E
S
L
S
L
F
E
A
Q
E
A
A
D
I
V
Q
D
A
A
D
E
D
V
N
M
I
F
G
T
V
I
N
P
E
L
Q
-
D
E
I
V
V
T
V
I
A
T
G
--
F
---------------------------------------------------
20
PsiBlast_PDB
90.07
43%
-86
- C3 -
3WGN
1
FTSZ_STAAM
A:
[31-316]
-----------------------------------------------
R
M
I
D
H
G
M
N
-
N
V
E
F
I
A
I
N
T
D
G
Q
A
L
N
L
S
K
A
E
S
K
I
Q
I
G
E
K
L
T
R
G
L
G
A
G
A
N
P
E
I
G
K
K
A
A
E
E
S
R
E
Q
I
E
D
A
I
Q
G
A
D
M
V
F
V
T
S
G
M
G
G
G
T
G
T
G
A
A
P
V
V
A
K
I
A
K
E
M
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
R
K
R
Q
T
Q
A
A
A
G
V
E
A
M
K
A
A
V
D
T
L
I
V
I
P
N
D
R
L
L
D
I
V
D
K
S
T
P
M
M
E
A
F
K
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
V
S
G
E
V
N
L
D
F
A
D
V
K
T
I
M
S
N
Q
G
S
A
L
M
G
I
G
V
S
S
G
E
N
R
A
V
E
A
A
K
K
A
I
S
S
P
L
L
-
E
T
S
I
V
G
A
Q
G
V
L
M
N
I
T
G
G
E
S
L
S
L
F
E
A
Q
E
A
A
D
I
V
Q
D
A
A
D
E
D
V
N
M
I
F
G
T
V
I
N
P
E
L
Q
-
D
E
I
V
V
T
V
I
A
T
G
--
F
---------------------------------------------------
15
PsiBlast_PDB
90.06
43%
-88
- C3 -
3VOA
2
FTSZ_STAAM
A:
[21-306]
-----------------------------------------------
R
M
I
D
H
G
M
N
-
N
V
E
F
I
A
I
N
T
D
G
Q
A
L
N
L
S
K
A
E
S
K
I
Q
I
G
E
K
L
T
R
G
L
G
A
G
A
N
P
E
I
G
K
K
A
A
E
E
S
R
E
Q
I
E
D
A
I
Q
G
A
D
M
V
F
V
T
S
G
M
G
G
G
T
G
T
G
A
A
P
V
V
A
K
I
A
K
E
M
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
R
K
R
Q
T
Q
A
A
A
G
V
E
A
M
K
A
A
V
D
T
L
I
V
I
P
N
D
R
L
L
D
I
V
D
K
S
T
P
M
M
E
A
F
K
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
V
S
G
E
V
N
L
D
F
A
D
V
K
T
I
M
S
N
Q
G
S
A
L
M
G
I
G
V
S
S
G
E
N
R
A
V
E
A
A
K
K
A
I
S
S
P
L
L
-
E
T
S
I
V
G
A
Q
G
V
L
M
N
I
T
G
G
E
S
L
S
L
F
E
A
Q
E
A
A
D
I
V
Q
D
A
A
D
E
D
V
N
M
I
F
G
T
V
I
N
P
E
L
Q
-
D
E
I
V
V
T
V
I
A
T
G
--
F
---------------------------------------------------
8
PsiBlast_PDB
90.04
43%
-93
- C3 -
2Q1X
1
FTSZ_MYCTU
A:
[22-311]
-------------------------------------------
N
A
V
N
R
M
I
E
Q
G
L
-
K
G
V
E
F
I
A
I
N
T
D
A
Q
A
L
L
M
S
D
A
D
V
K
L
D
V
G
R
D
S
-------
A
D
P
E
V
G
R
K
A
A
E
D
A
K
D
E
I
E
E
L
L
R
G
A
D
M
V
F
V
T
A
G
E
G
G
G
T
G
T
G
G
A
P
V
V
A
S
I
A
R
K
L
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
K
R
R
S
N
Q
A
E
N
G
I
A
A
L
R
E
S
C
D
T
L
I
V
I
P
N
D
R
L
L
Q
M
G
D
A
A
V
S
L
M
D
A
F
R
S
A
D
E
V
L
L
N
G
V
Q
G
I
T
D
L
I
T
T
P
G
L
I
N
V
D
F
A
D
V
K
G
I
M
S
G
A
G
T
A
L
M
G
I
G
S
A
R
G
E
G
R
S
L
K
A
A
E
I
A
I
N
S
P
L
L
-
E
A
S
M
E
G
A
Q
G
V
L
M
S
I
A
G
G
S
D
L
G
L
F
E
I
N
E
A
A
S
L
V
Q
D
A
A
H
P
D
A
N
I
I
F
G
T
V
I
D
D
S
L
G
-
D
E
V
R
V
T
V
I
A
A
G
--
F
---------------------------------------------------
30
PsiBlast_CBE
89.95
43%
-89
- C3 -
3WGN
1
FTSZ_STAAM
B:
[31-316]
-----------------------------------------------
R
M
I
D
H
G
M
N
-
N
V
E
F
I
A
I
N
T
D
G
Q
A
L
N
L
S
K
A
E
S
K
I
Q
I
G
E
K
L
T
R
G
L
G
A
G
A
N
P
E
I
G
K
K
A
A
E
E
S
R
E
Q
I
E
D
A
I
Q
G
A
D
M
V
F
V
T
S
G
M
G
G
G
T
G
T
G
A
A
P
V
V
A
K
I
A
K
E
M
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
R
K
R
Q
T
Q
A
A
A
G
V
E
A
M
K
A
A
V
D
T
L
I
V
I
P
N
D
R
L
L
D
I
V
D
K
S
T
P
M
M
E
A
F
K
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
V
S
G
E
V
N
L
D
F
A
D
V
K
T
I
M
S
N
Q
G
S
A
L
M
G
I
G
V
S
S
G
E
N
R
A
V
E
A
A
K
K
A
I
S
S
P
L
L
-
E
T
S
I
V
G
A
Q
G
V
L
M
N
I
T
G
G
E
S
L
S
L
F
E
A
Q
E
A
A
D
I
V
Q
D
A
A
D
E
D
V
N
M
I
F
G
T
V
I
N
P
E
L
Q
-
D
E
I
V
V
T
V
I
A
T
G
--
F
---------------------------------------------------
19
PsiBlast_PDB
89.60
43%
-87
- C3 -
3VO8
2
FTSZ_STAAM
A:
[31-316]
-----------------------------------------------
R
M
I
D
H
G
M
N
-
N
V
E
F
I
A
I
N
T
D
G
Q
A
L
N
L
S
K
A
E
S
K
I
Q
I
G
E
K
L
T
R
G
L
G
A
G
A
N
P
E
I
G
K
K
A
A
E
E
S
R
E
Q
I
E
D
A
I
Q
G
A
D
M
V
F
V
T
S
G
M
G
G
G
T
G
T
G
A
A
P
V
V
A
K
I
A
K
E
M
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
R
K
R
Q
T
Q
A
A
A
G
V
E
A
M
K
A
A
V
D
T
L
I
V
I
P
N
D
R
L
L
D
I
V
D
K
S
T
P
M
M
E
A
F
K
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
V
S
G
E
V
N
L
D
F
A
D
V
K
T
I
M
S
N
Q
G
S
A
L
M
G
I
G
V
S
S
G
E
N
R
A
V
E
A
A
K
K
A
I
S
S
P
L
L
-
E
T
S
I
V
G
A
Q
G
V
L
M
N
I
T
G
G
E
S
L
S
L
F
E
A
Q
E
A
A
D
I
V
Q
D
A
A
D
E
D
V
N
M
I
F
G
T
V
I
N
P
E
L
Q
-
D
E
I
V
V
T
V
I
A
T
G
--
F
D
--------------------------------------------------
17
PsiBlast_PDB
89.55
43%
-90
- C3 -
4DXD
2
FTSZ_STAAU
A:
[35-320]
-----------------------------------------------
R
M
I
D
H
G
M
N
-
N
V
E
F
I
A
I
N
T
D
G
Q
A
L
N
L
S
K
A
E
S
K
I
Q
I
G
E
K
L
T
R
G
L
G
A
G
A
N
P
E
I
G
K
K
A
A
E
E
S
R
E
Q
I
E
D
A
I
Q
G
A
D
M
V
F
V
T
S
G
M
G
G
G
T
G
T
G
A
A
P
V
V
A
K
I
A
K
E
M
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
R
K
R
Q
T
Q
A
A
A
G
V
E
A
M
K
A
A
V
D
T
L
I
V
I
P
N
D
R
L
L
D
I
V
D
K
S
T
P
M
M
E
A
F
K
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
V
S
G
E
V
N
L
D
F
A
D
V
K
T
I
M
S
N
Q
G
S
A
L
M
G
I
G
V
S
S
G
E
N
R
A
V
E
A
A
K
K
A
I
S
S
P
L
L
-
E
T
S
I
V
G
A
Q
G
V
L
M
N
I
T
G
G
E
S
L
S
L
F
E
A
Q
E
A
A
D
I
V
Q
D
A
A
D
E
D
V
N
M
I
F
G
T
V
I
N
P
E
L
Q
-
D
E
I
V
V
T
V
I
A
T
G
--
F
D
D
K
------------------------------------------------
41
PsiBlast_CBE
89.50
42%
-92
- C3 -
3WGK
1
FTSZ_STAAM
B:
[31-314]
-----------------------------------------------
R
M
I
D
H
G
M
N
-
N
V
E
F
I
A
I
N
T
D
G
Q
A
L
N
L
S
K
A
E
S
K
I
Q
I
G
E
K
L
T
R
G
L
G
A
G
A
N
P
E
I
G
K
K
A
A
E
E
S
R
E
Q
I
E
D
A
I
Q
G
A
D
M
V
F
V
T
S
G
M
G
G
G
T
G
T
G
A
A
P
V
V
A
K
I
A
K
E
M
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
R
K
R
Q
T
Q
A
A
A
G
V
E
A
M
K
A
A
V
D
T
L
I
V
I
P
N
D
R
L
L
D
I
V
D
K
S
T
P
M
M
E
A
F
K
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
V
G
A
G
L
--
D
F
A
D
V
K
T
I
M
S
N
Q
G
S
A
L
M
G
I
G
V
S
S
G
E
N
R
A
V
E
A
A
K
K
A
I
S
S
P
L
L
-
E
T
S
I
V
G
A
Q
G
V
L
M
N
I
T
G
G
E
S
L
S
L
F
E
A
Q
E
A
A
D
I
V
Q
D
A
A
D
E
D
V
N
M
I
F
G
T
V
I
N
P
E
L
Q
-
D
E
I
V
V
T
V
I
A
T
G
--
F
D
--------------------------------------------------
16
PsiBlast_PDB
89.43
43%
-85
- C3 -
3VOB
3
FTSZ_STAAM
A:
[21-306]
-----------------------------------------------
R
M
I
D
H
G
M
N
-
N
V
E
F
I
A
I
N
T
D
G
Q
A
L
N
L
S
K
A
E
S
K
I
Q
I
G
E
K
L
T
R
G
L
G
A
G
A
N
P
E
I
G
K
K
A
A
E
E
S
R
E
Q
I
E
D
A
I
Q
G
A
D
M
V
F
V
T
S
G
M
G
G
G
T
G
T
G
A
A
P
V
V
A
K
I
A
K
E
M
G
A
L
T
V
G
V
V
T
R
P
F
S
F
E
G
R
K
R
Q
T
Q
A
A
A
G
V
E
A
M
K
A
A
V
D
T
L
I
V
I
P
N
D
R
L
L
D
I
V
D
K
S
T
P
M
M
E
A
F
K
E
A
D
N
V
L
R
Q
G
V
Q
G
I
S
D
L
I
A
V
S
G
E
V
N
L
D
F
A
D
V
K
T
I
M
S
N
Q
G
S
A
L
M
G
I
G
V
S
S
G
E
N
R
A
V
E
A
A
K
K
A
I
S
S
P
L
L
-
E
T
S
I
V
G
A
Q
G
V
L
M
N
I
T
G
G
E
S
L
S
L
F
E
A
Q
E
A
A
D
I
V
Q
D
A
A
D
E
D
V
N
M
I
F
G
T
V
I
N
P
E
L
Q
-
D
E
I
V
V
T
V
I
A
T
G
--
F
---------------------------------------------------